5DQFA

Horse serum albumin (esa) in complex with cetirizine
Total Genus 238
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
238
sequence length
580
structure length
580
Chain Sequence
KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug binding site.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 238
structure length 580
sequence length 580
ec nomenclature
pdb deposition date 2015-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA05
1TF0A 1E7FA 4L8UA 5IJEA 5DQFA 1BKEA 4LB9A 1LOTA 2BXGA 4L9QA 1HA2A 1HK3A 1GNJA 2XVWA 2VUFA 3V03A 2BX8A 3JQZA 4L9KA 1HK5A 4G03A 2BXDA 1E78A 5ID9A 4PO0A 1BM0A 2BXEA 5IFOA 1E7IA 1E7EA 5FUOA 4LUHA 1J7EA 4IW2A 4LUFA 4OT2A 4Z69A 4BKEA 2BXFA 1KW2A 3B9LA 2I30A 3V09A 1E7AA 3B9MA 4N0UD 2XW0A 4K2CA 4LA0A 5IIXA 4J2VA 2VUEA 1E7CA 3TDLA 4IW1A 4K71A 2BXCA 2BXHA 5IJ5A 1E7GA 4HGKA 5IIUA 4HGMB 5IJFA 1GNIA 2BXPA 2XVQA 2BXLA 4LB2A 2XSIA 4G04A 3SQJA 2BXQA 1AO6A 5IIHA 4OR0A 4ZBQA 1N5UA 4F5UA 1H9ZA 3CX9A 1E7BA 5HOZA 3V08A 1UORA 1E7HA 4S1YA 1HK2A 1HK1A 2BXIA 2BXOA 1O9XA 3UIVA 4JK4A 1HK4A 2BXMA 2VDBA 3A73A 2YDFA 4F5TA 4ZBRA 2XW1A 5DBYA 1J78A 3JRYA 2XVUA 3LU7A 2BXAA 2I2ZA 1KXPD 3LU6A 2BXNA 4N0FD 2XVVA 4EMXA 2BXKA 4F5SA 5ID7A 4F5VA 4E99A 5GHKA 1BJ5A 2BXBA 1MA9A 3LU8A
chains in the Genus database with same CATH superfamily
1TF0A 1E7FA 2DYOA 1VZSA 2LXTA 2Z8IA 4L8UA 5IJEA 5DQFA 1BKEA 4LB9A 1LOTA 2BXGA 4GG2A 4DM0A 1MIVA 3GA9L 4L9QA 4W4UB 3WHRA 1HA2A 2QHBA 1HK3A 2LQIA 2QMCA 3H37A 2DBWA 2LXSA 1GNJA 2EFEA 2XVWA 2VUFA 3V03A 1MUSA 2BX8A 3A75A 3JQZA 4L9KA 2KWFA 1HK5A 4G03A 2BXDA 1E78A 5ID9A 4GDKB 2DYMA 4OTUA 3G9KD 4PO0A 4DHXB 1BM0A 2BXEA 2OT3A 5IFOA 3MHHB 3ECPA 1TXUA 1E7IA 1E7EA 3VQIA 2E0YA 3WHSA 3KJLA 4LUHA 5FUOA 1J7EA 1MIYA 3M99C 2E0XA 4GDLB 4IW2A 4LUFA 4OT2A 3MHSB 4I9OA 4Z69A 4BKEA 4ZUXV 1JNBA 4FIPB 1H5WA 2Z8KA 3NVKA 4ZCGA 3SIUB 5GIOA 2BXFA 1KW2A 4C31B 4N3ZA 3B9LA 2I30A 3V09A 1E7AA 2EFDA 5D7GA 4G01A 5B5TA 3B9MA 4N0UD 2XW0A 4K2CA 4LA0A 5IIXA 4J2VA 2NQOA 1E7CA 2VUEA 4ZC6A 3TDLA 4IW1A 4K71A 2BXCA 2BXHA 5IJ5A 1E7GA 4HGKA 4BY9C 3KIKA 5IIUA 4HGMB 5IJFA 1GNIA 2BXPA 2XVQA 2BXLA 4ZBKA 4LB2A 2XSIA 2Z8JA 2DBUA 3BPJA 4G04A 3SQJA 2BXQA 3FWBC 3WHQA 2CKXA 1AO6A 5IIHA 2QM6A 1IJGA 4OR0A 4TQ1A 4ZBQA 1N5UA 1MIWA 2AGHB 1KDXA 4F5UA 1H9ZA 3CX9A 2EFCA 2JUHA 1LNSA 2DG5A 4FJCB 3PLAA 1E7BA 5HOZA 3V08A 1UORA 2EFHA 5GINA 4M70B 1E7HA 3SIVB 4S1YA 1HK2A 2KBZA 1HK1A 2BXIA 2BXOA 1O9XA 3GQXA 4JK4A 1HK4A 2GUTA 3UIVA 2K0NA 2LOQA 2AJEA 2DBXA 2BXMA 2VDBA 3A73A 2YDFA 4F5TA 2OZBB 4ZBRA 2XW1A 5DBYA 3NVIA 3NMUA 2V36A 4Z9OA 1VFIA 2ROHA 1MUHA 4WA6B 4NAWB 3FNMA 2LQHA 2NNWA 1J78A 3JRYA 3GQUA 4TQ0A 2XVUA 3LU7A 2XMOA 4GDXA 3NVMA 4OTTA 2BXAA 2I2ZA 1MM8A 1KXPD 1FOUA 3LU6A 2BXNA 3H3AA 4N0FD 2XVVA 3W1SA 4FK5B 4EMXA 3FWCC 2BXKA 4F5SA 3ICXA 5ID7A 5GIPA 4F5VA 1SB0A 4D7XA 5GHKA 1BJ5A 4E99A 5BPKA 4MBEC 1NT2B 2BXBA 1MA9A 3LU8A
chains in the Genus database with same CATH topology
1TF0A 1E7FA 2DYOA 1VZSA 2Z8IA 4L8UA 5IJEA 5DQFA 1BKEA 4LB9A 1LOTA 2BXGA 4GG2A 1MIVA 3GA9L 4L9QA 4W4UB 3WHRA 1HA2A 2QHBA 1HK3A 2QMCA 3H37A 2DBWA 1GNJA 2EFEA 2XVWA 2VUFA 3V03A 2BX8A 3A75A 3JQZA 4L9KA 1HK5A 4G03A 2BXDA 1E78A 5ID9A 4GDKB 2DYMA 4OTUA 3G9KD 4PO0A 4DHXB 1BM0A 2BXEA 2OT3A 5IFOA 3MHHB 1TXUA 1E7IA 1E7EA 3VQIA 2E0YA 3WHSA 3KJLA 4LUHA 5FUOA 1J7EA 1MIYA 3M99C 2E0XA 4GDLB 4IW2A 4LUFA 4OT2A 3MHSB 4Z69A 4BKEA 4ZUXV 1JNBA 4FIPB 1H5WA 2Z8KA 3NVKA 4ZCGA 3SIUB 5GIOA 2BXFA 1KW2A 4C31B 4N3ZA 3B9LA 2I30A 3V09A 1E7AA 2EFDA 5D7GA 4G01A 5B5TA 3B9MA 4N0UD 2XW0A 4K2CA 4LA0A 5IIXA 4J2VA 2NQOA 1E7CA 2VUEA 4ZC6A 3TDLA 4IW1A 4K71A 2BXCA 2BXHA 5IJ5A 1E7GA 4HGKA 4BY9C 3KIKA 5IIUA 4HGMB 5IJFA 1GNIA 2BXPA 2XVQA 2BXLA 4ZBKA 4LB2A 2XSIA 2Z8JA 2DBUA 4G04A 3SQJA 2BXQA 3FWBC 3WHQA 2CKXA 1AO6A 5IIHA 2QM6A 1IJGA 4OR0A 4TQ1A 4ZBQA 1N5UA 1MIWA 4F5UA 1H9ZA 3CX9A 2EFCA 2JUHA 1LNSA 2DG5A 4FJCB 3PLAA 1E7BA 5HOZA 3V08A 1UORA 2EFHA 5GINA 4M70B 1E7HA 3SIVB 4S1YA 1HK2A 2KBZA 1HK1A 2BXIA 2BXOA 1O9XA 3GQXA 4JK4A 1HK4A 3UIVA 2LOQA 2AJEA 2DBXA 2BXMA 2VDBA 3A73A 2YDFA 4F5TA 2OZBB 4ZBRA 2XW1A 5DBYA 3NVIA 3NMUA 2V36A 4Z9OA 1VFIA 2ROHA 4WA6B 4NAWB 3FNMA 2NNWA 1J78A 3JRYA 3GQUA 4TQ0A 2XVUA 3LU7A 2XMOA 4GDXA 3NVMA 4OTTA 2BXAA 2I2ZA 1KXPD 1FOUA 3LU6A 2BXNA 3H3AA 4N0FD 2XVVA 3W1SA 4FK5B 4EMXA 3FWCC 2BXKA 4F5SA 3ICXA 5ID7A 5GIPA 4F5VA 4E99A 5GHKA 1BJ5A 5BPKA 4MBEC 1NT2B 2BXBA 1MA9A 3LU8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TF0 A;  1E7F A;  4L8U A;  5IJE A;  5DQF A;  1BKE A;  4LB9 A;  1LOT A;  2BXG A;  4L9Q A;  1HA2 A;  1HK3 A;  1GNJ A;  2XVW A;  2VUF A;  3V03 A;  2BX8 A;  3JQZ A;  4L9K A;  1HK5 A;  4G03 A;  2BXD A;  1E78 A;  5ID9 A;  4PO0 A;  1BM0 A;  2BXE A;  5IFO A;  1E7I A;  1E7E A;  5FUO A;  4LUH A;  1J7E A;  4IW2 A;  4LUF A;  4OT2 A;  4Z69 A;  4BKE A;  2BXF A;  1KW2 A;  3B9L A;  2I30 A;  3V09 A;  1E7A A;  3B9M A;  4N0U D;  2XW0 A;  4K2C A;  4LA0 A;  5IIX A;  4J2V A;  2VUE A;  1E7C A;  3TDL A;  4IW1 A;  4K71 A;  2BXC A;  2BXH A;  5IJ5 A;  1E7G A;  4HGK A;  5IIU A;  4HGM B;  5IJF A;  1GNI A;  2BXP A;  2XVQ A;  2BXL A;  4LB2 A;  2XSI A;  4G04 A;  3SQJ A;  2BXQ A;  1AO6 A;  5IIH A;  4OR0 A;  4ZBQ A;  1N5U A;  4F5U A;  1H9Z A;  3CX9 A;  1E7B A;  5HOZ A;  3V08 A;  1UOR A;  1E7H A;  4S1Y A;  1HK2 A;  1HK1 A;  2BXI A;  2BXO A;  1O9X A;  3UIV A;  4JK4 A;  1HK4 A;  2BXM A;  2VDB A;  3A73 A;  2YDF A;  4F5T A;  4ZBR A;  2XW1 A;  5DBY A;  1J78 A;  3JRY A;  2XVU A;  3LU7 A;  2BXA A;  2I2Z A;  1KXP D;  3LU6 A;  2BXN A;  4N0F D;  2XVV A;  4EMX A;  2BXK A;  4F5S A;  5ID7 A;  4F5V A;  4E99 A;  5GHK A;  1BJ5 A;  2BXB A;  1MA9 A;  3LU8 A; 
#chains in the Genus database with same CATH topology
 1TF0 A;  1E7F A;  2DYO A;  1VZS A;  2LXT A;  2Z8I A;  4L8U A;  5IJE A;  5DQF A;  1BKE A;  4LB9 A;  1LOT A;  2BXG A;  4GG2 A;  4DM0 A;  1MIV A;  3GA9 L;  4L9Q A;  4W4U B;  3WHR A;  1HA2 A;  2QHB A;  1HK3 A;  2LQI A;  2QMC A;  3H37 A;  2DBW A;  2LXS A;  1GNJ A;  2EFE A;  2XVW A;  2VUF A;  3V03 A;  1MUS A;  2BX8 A;  3A75 A;  3JQZ A;  4L9K A;  2KWF A;  1HK5 A;  4G03 A;  2BXD A;  1E78 A;  5ID9 A;  4GDK B;  2DYM A;  4OTU A;  3G9K D;  4PO0 A;  4DHX B;  1BM0 A;  2BXE A;  2OT3 A;  5IFO A;  3MHH B;  3ECP A;  1TXU A;  1E7I A;  1E7E A;  3VQI A;  2E0Y A;  3WHS A;  3KJL A;  4LUH A;  5FUO A;  1J7E A;  1MIY A;  3M99 C;  2E0X A;  4GDL B;  4IW2 A;  4LUF A;  4OT2 A;  3MHS B;  4I9O A;  4Z69 A;  4BKE A;  4ZUX V;  1JNB A;  4FIP B;  1H5W A;  2Z8K A;  3NVK A;  4ZCG A;  3SIU B;  5GIO A;  2BXF A;  1KW2 A;  4C31 B;  4N3Z A;  3B9L A;  2I30 A;  3V09 A;  1E7A A;  2EFD A;  5D7G A;  4G01 A;  5B5T A;  3B9M A;  4N0U D;  2XW0 A;  4K2C A;  4LA0 A;  5IIX A;  4J2V A;  2NQO A;  1E7C A;  2VUE A;  4ZC6 A;  3TDL A;  4IW1 A;  4K71 A;  2BXC A;  2BXH A;  5IJ5 A;  1E7G A;  4HGK A;  4BY9 C;  3KIK A;  5IIU A;  4HGM B;  5IJF A;  1GNI A;  2BXP A;  2XVQ A;  2BXL A;  4ZBK A;  4LB2 A;  2XSI A;  2Z8J A;  2DBU A;  3BPJ A;  4G04 A;  3SQJ A;  2BXQ A;  3FWB C;  3WHQ A;  2CKX A;  1AO6 A;  5IIH A;  2QM6 A;  1IJG A;  4OR0 A;  4TQ1 A;  4ZBQ A;  1N5U A;  1MIW A;  2AGH B;  1KDX A;  4F5U A;  1H9Z A;  3CX9 A;  2EFC A;  2JUH A;  1LNS A;  2DG5 A;  4FJC B;  3PLA A;  1E7B A;  5HOZ A;  3V08 A;  1UOR A;  2EFH A;  5GIN A;  4M70 B;  1E7H A;  3SIV B;  4S1Y A;  1HK2 A;  2KBZ A;  1HK1 A;  2BXI A;  2BXO A;  1O9X A;  3GQX A;  4JK4 A;  1HK4 A;  2GUT A;  3UIV A;  2K0N A;  2LOQ A;  2AJE A;  2DBX A;  2BXM A;  2VDB A;  3A73 A;  2YDF A;  4F5T A;  2OZB B;  4ZBR A;  2XW1 A;  5DBY A;  3NVI A;  3NMU A;  2V36 A;  4Z9O A;  1VFI A;  2ROH A;  1MUH A;  4WA6 B;  4NAW B;  3FNM A;  2LQH A;  2NNW A;  1J78 A;  3JRY A;  3GQU A;  4TQ0 A;  2XVU A;  3LU7 A;  2XMO A;  4GDX A;  3NVM A;  4OTT A;  2BXA A;  2I2Z A;  1MM8 A;  1KXP D;  1FOU A;  3LU6 A;  2BXN A;  3H3A A;  4N0F D;  2XVV A;  3W1S A;  4FK5 B;  4EMX A;  3FWC C;  2BXK A;  4F5S A;  3ICX A;  5ID7 A;  5GIP A;  4F5V A;  1SB0 A;  4D7X A;  5GHK A;  1BJ5 A;  4E99 A;  5BPK A;  4MBE C;  1NT2 B;  2BXB A;  1MA9 A;  3LU8 A; 
#chains in the Genus database with same CATH homology
 1TF0 A;  1E7F A;  2DYO A;  1VZS A;  2Z8I A;  4L8U A;  5IJE A;  5DQF A;  1BKE A;  4LB9 A;  1LOT A;  2BXG A;  4GG2 A;  1MIV A;  3GA9 L;  4L9Q A;  4W4U B;  3WHR A;  1HA2 A;  2QHB A;  1HK3 A;  2QMC A;  3H37 A;  2DBW A;  1GNJ A;  2EFE A;  2XVW A;  2VUF A;  3V03 A;  2BX8 A;  3A75 A;  3JQZ A;  4L9K A;  1HK5 A;  4G03 A;  2BXD A;  1E78 A;  5ID9 A;  4GDK B;  2DYM A;  4OTU A;  3G9K D;  4PO0 A;  4DHX B;  1BM0 A;  2BXE A;  2OT3 A;  5IFO A;  3MHH B;  1TXU A;  1E7I A;  1E7E A;  3VQI A;  2E0Y A;  3WHS A;  3KJL A;  4LUH A;  5FUO A;  1J7E A;  1MIY A;  3M99 C;  2E0X A;  4GDL B;  4IW2 A;  4LUF A;  4OT2 A;  3MHS B;  4Z69 A;  4BKE A;  4ZUX V;  1JNB A;  4FIP B;  1H5W A;  2Z8K A;  3NVK A;  4ZCG A;  3SIU B;  5GIO A;  2BXF A;  1KW2 A;  4C31 B;  4N3Z A;  3B9L A;  2I30 A;  3V09 A;  1E7A A;  2EFD A;  5D7G A;  4G01 A;  5B5T A;  3B9M A;  4N0U D;  2XW0 A;  4K2C A;  4LA0 A;  5IIX A;  4J2V A;  2NQO A;  1E7C A;  2VUE A;  4ZC6 A;  3TDL A;  4IW1 A;  4K71 A;  2BXC A;  2BXH A;  5IJ5 A;  1E7G A;  4HGK A;  4BY9 C;  3KIK A;  5IIU A;  4HGM B;  5IJF A;  1GNI A;  2BXP A;  2XVQ A;  2BXL A;  4ZBK A;  4LB2 A;  2XSI A;  2Z8J A;  2DBU A;  4G04 A;  3SQJ A;  2BXQ A;  3FWB C;  3WHQ A;  2CKX A;  1AO6 A;  5IIH A;  2QM6 A;  1IJG A;  4OR0 A;  4TQ1 A;  4ZBQ A;  1N5U A;  1MIW A;  4F5U A;  1H9Z A;  3CX9 A;  2EFC A;  2JUH A;  1LNS A;  2DG5 A;  4FJC B;  3PLA A;  1E7B A;  5HOZ A;  3V08 A;  1UOR A;  2EFH A;  5GIN A;  4M70 B;  1E7H A;  3SIV B;  4S1Y A;  1HK2 A;  2KBZ A;  1HK1 A;  2BXI A;  2BXO A;  1O9X A;  3GQX A;  4JK4 A;  1HK4 A;  3UIV A;  2LOQ A;  2AJE A;  2DBX A;  2BXM A;  2VDB A;  3A73 A;  2YDF A;  4F5T A;  2OZB B;  4ZBR A;  2XW1 A;  5DBY A;  3NVI A;  3NMU A;  2V36 A;  4Z9O A;  1VFI A;  2ROH A;  4WA6 B;  4NAW B;  3FNM A;  2NNW A;  1J78 A;  3JRY A;  3GQU A;  4TQ0 A;  2XVU A;  3LU7 A;  2XMO A;  4GDX A;  3NVM A;  4OTT A;  2BXA A;  2I2Z A;  1KXP D;  1FOU A;  3LU6 A;  2BXN A;  3H3A A;  4N0F D;  2XVV A;  3W1S A;  4FK5 B;  4EMX A;  3FWC C;  2BXK A;  4F5S A;  3ICX A;  5ID7 A;  5GIP A;  4F5V A;  4E99 A;  5GHK A;  1BJ5 A;  5BPK A;  4MBE C;  1NT2 B;  2BXB A;  1MA9 A;  3LU8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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