5IFOA

X-ray structure of hsa-myr-kp1019
Total Genus 200
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
200
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 200
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2016-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ifoA05
2VUEA 2XVUA 2VUFA 3CX9A 2XSIA 4L9QA 5IIXA 2BXFA 4L9KA 5DBYA 3B9MA 4J2VA 1J78A 4G04A 2BXPA 3V09A 2BXEA 1HK1A 1UORA 4PO0A 1GNJA 1HK5A 4LB2A 4OT2A 4IW2A 4OR0A 4K71A 4ZBQA 1E7FA 2BX8A 1HK2A 2XVQA 4F5SA 4LA0A 1E7AA 1HA2A 1BKEA 2YDFA 2BXGA 4Z69A 4F5VA 2XVWA 2XVVA 1E7HA 1BJ5A 4EMXA 5HOZA 4N0UD 4L8UA 3UIVA 4S1YA 4BKEA 5DQFA 4IW1A 3LU6A 5IIUA 5GHKA 4LUFA 4F5UA 4K2CA 2BXMA 2BXHA 4E99A 3SQJA 5ID9A 2BXBA 2BXLA 1KXPD 4LB9A 3V03A 5IJFA 1BM0A 3A73A 2XW1A 1LOTA 2BXCA 4HGMB 1J7EA 2BXAA 1KW2A 5FUOA 1HK3A 1H9ZA 1N5UA 2I2ZA 1O9XA 1GNIA 2I30A 1MA9A 3JRYA 3V08A 2BXKA 2BXNA 3LU8A 1TF0A 2BXOA 4HGKA 3B9LA 5IJEA 4ZBRA 3TDLA 2BXIA 1HK4A 4G03A 1E7BA 1E78A 3LU7A 5IFOA 1E7IA 5IIHA 3JQZA 5ID7A 2XW0A 4LUHA 1E7GA 1E7CA 4F5TA 1AO6A 5IJ5A 2BXDA 4JK4A 4N0FD 2BXQA 2VDBA 1E7EA
chains in the Genus database with same CATH superfamily
4OTUA 4FJCB 3KJLA 2VUEA 2XVUA 2VUFA 3CX9A 2NQOA 2XSIA 2DG5A 2LXTA 4L9QA 5IIXA 3FNMA 2LXSA 4ZCGA 3ICXA 2BXFA 4L9KA 5DBYA 1TXUA 3MHSB 3SIUB 2EFCA 2LQHA 4D7XA 3B9MA 4J2VA 2DBWA 3GA9L 1J78A 4G04A 2BXPA 3V09A 2BXEA 1HK1A 1UORA 4PO0A 1GNJA 4NAWB 4BY9C 1HK5A 4LB2A 4OT2A 4IW2A 4OR0A 1LNSA 3SIVB 4K71A 2E0XA 4ZBQA 1E7FA 3PLAA 2BX8A 1HK2A 2XVQA 3FWCC 2AGHB 4F5SA 4GG2A 2KBZA 5BPKA 3MHHB 2EFHA 3H37A 4FIPB 4LA0A 3WHQA 3ECPA 1E7AA 4FK5B 1HA2A 4MBEC 4TQ0A 1BKEA 2YDFA 3A75A 1MUHA 2BXGA 2Z8IA 4Z69A 3GQUA 2DBXA 3WHSA 4F5VA 2QMCA 2XVWA 3VQIA 2XVVA 1E7HA 1BJ5A 4EMXA 5HOZA 1MIWA 2Z8KA 4N0UD 4L8UA 3UIVA 4GDLB 4S1YA 4BKEA 5DQFA 4TQ1A 3W1SA 3G9KD 1JNBA 4IW1A 3LU6A 5B5TA 5IIUA 2DBUA 1FOUA 4LUFA 5GHKA 2Z8JA 4F5UA 4K2CA 2BXMA 2BXHA 1MIVA 1MUSA 3KIKA 4E99A 3SQJA 5ID9A 2BXBA 2LOQA 4GDKB 5D7GA 2BXLA 1VFIA 1KXPD 2V36A 2QM6A 4LB9A 4OTTA 1BM0A 2EFDA 4ZBKA 3V03A 5IJFA 3A73A 5GINA 2XW1A 4M70B 1LOTA 3NMUA 2BXCA 4HGMB 2DYMA 1H5WA 1J7EA 2BXAA 4G01A 1KW2A 5FUOA 1HK3A 1H9ZA 1N5UA 2I2ZA 2KWFA 2E0YA 1O9XA 4GDXA 1GNIA 5GIOA 2I30A 1MA9A 2LQIA 2DYOA 2NNWA 3NVMA 3M99C 4ZC6A 4C31B 3NVIA 3JRYA 3V08A 2BXKA 2BXNA 3LU8A 3GQXA 1TF0A 2AJEA 2BXOA 4HGKA 3B9LA 2QHBA 5IJEA 1VZSA 2K0NA 4ZBRA 1NT2B 2ROHA 2GUTA 4W4UB 3TDLA 4DM0A 2BXIA 1SB0A 2OT3A 1HK4A 4I9OA 2CKXA 4G03A 1E7BA 1E78A 3LU7A 4WA6B 2OZBB 2JUHA 5IFOA 1E7IA 5IIHA 3H3AA 3JQZA 4Z9OA 5ID7A 1MM8A 2XW0A 4LUHA 1E7GA 1MIYA 4N3ZA 4DHXB 4ZUXV 1KDXA 2EFEA 1E7CA 3WHRA 4F5TA 3FWBC 3NVKA 1AO6A 5IJ5A 3BPJA 2BXDA 4JK4A 4N0FD 1IJGA 2BXQA 2VDBA 2XMOA 5GIPA 1E7EA
chains in the Genus database with same CATH topology
4OTUA 4FJCB 3KJLA 2VUEA 2XVUA 2VUFA 3CX9A 2NQOA 2XSIA 2DG5A 4L9QA 5IIXA 3FNMA 4ZCGA 3ICXA 2BXFA 4L9KA 5DBYA 1TXUA 3MHSB 3SIUB 2EFCA 3B9MA 4J2VA 2DBWA 3GA9L 1J78A 4G04A 2BXPA 3V09A 2BXEA 1HK1A 1UORA 4PO0A 1GNJA 4NAWB 4BY9C 1HK5A 4LB2A 4OT2A 4IW2A 4OR0A 1LNSA 3SIVB 4K71A 2E0XA 4ZBQA 1E7FA 3PLAA 2BX8A 1HK2A 2XVQA 3FWCC 4F5SA 4GG2A 2KBZA 5BPKA 3MHHB 2EFHA 3H37A 4FIPB 4LA0A 3WHQA 1E7AA 4FK5B 1HA2A 4MBEC 4TQ0A 1BKEA 2YDFA 3A75A 2BXGA 2Z8IA 4Z69A 3GQUA 2DBXA 3WHSA 4F5VA 2QMCA 2XVWA 3VQIA 2XVVA 1E7HA 1BJ5A 4EMXA 5HOZA 1MIWA 2Z8KA 4N0UD 4L8UA 3UIVA 4GDLB 4S1YA 4BKEA 5DQFA 4TQ1A 3W1SA 3G9KD 1JNBA 4IW1A 3LU6A 5B5TA 5IIUA 2DBUA 1FOUA 4LUFA 5GHKA 2Z8JA 4F5UA 4K2CA 2BXMA 2BXHA 1MIVA 3KIKA 4E99A 3SQJA 5ID9A 2BXBA 2LOQA 4GDKB 5D7GA 2BXLA 1VFIA 1KXPD 2V36A 2QM6A 4LB9A 4OTTA 1BM0A 2EFDA 4ZBKA 3V03A 5IJFA 3A73A 5GINA 2XW1A 4M70B 1LOTA 3NMUA 2BXCA 4HGMB 2DYMA 1H5WA 1J7EA 2BXAA 4G01A 1KW2A 5FUOA 1HK3A 1H9ZA 1N5UA 2I2ZA 2E0YA 1O9XA 4GDXA 1GNIA 5GIOA 2I30A 1MA9A 2DYOA 2NNWA 3NVMA 3M99C 4ZC6A 4C31B 3NVIA 3JRYA 3V08A 2BXKA 2BXNA 3LU8A 3GQXA 1TF0A 2AJEA 2BXOA 4HGKA 3B9LA 2QHBA 5IJEA 1VZSA 4ZBRA 1NT2B 2ROHA 4W4UB 3TDLA 2BXIA 2OT3A 1HK4A 2CKXA 4G03A 1E7BA 1E78A 3LU7A 4WA6B 2OZBB 2JUHA 5IFOA 1E7IA 5IIHA 3H3AA 3JQZA 4Z9OA 5ID7A 2XW0A 4LUHA 1E7GA 1MIYA 4N3ZA 4DHXB 4ZUXV 2EFEA 1E7CA 3WHRA 4F5TA 3FWBC 3NVKA 1AO6A 5IJ5A 2BXDA 4JK4A 4N0FD 1IJGA 2BXQA 2VDBA 2XMOA 5GIPA 1E7EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VUE A;  2XVU A;  2VUF A;  3CX9 A;  2XSI A;  4L9Q A;  5IIX A;  2BXF A;  4L9K A;  5DBY A;  3B9M A;  4J2V A;  1J78 A;  4G04 A;  2BXP A;  3V09 A;  2BXE A;  1HK1 A;  1UOR A;  4PO0 A;  1GNJ A;  1HK5 A;  4LB2 A;  4OT2 A;  4IW2 A;  4OR0 A;  4K71 A;  4ZBQ A;  1E7F A;  2BX8 A;  1HK2 A;  2XVQ A;  4F5S A;  4LA0 A;  1E7A A;  1HA2 A;  1BKE A;  2YDF A;  2BXG A;  4Z69 A;  4F5V A;  2XVW A;  2XVV A;  1E7H A;  1BJ5 A;  4EMX A;  5HOZ A;  4N0U D;  4L8U A;  3UIV A;  4S1Y A;  4BKE A;  5DQF A;  4IW1 A;  3LU6 A;  5IIU A;  5GHK A;  4LUF A;  4F5U A;  4K2C A;  2BXM A;  2BXH A;  4E99 A;  3SQJ A;  5ID9 A;  2BXB A;  2BXL A;  1KXP D;  4LB9 A;  3V03 A;  5IJF A;  1BM0 A;  3A73 A;  2XW1 A;  1LOT A;  2BXC A;  4HGM B;  1J7E A;  2BXA A;  1KW2 A;  5FUO A;  1HK3 A;  1H9Z A;  1N5U A;  2I2Z A;  1O9X A;  1GNI A;  2I30 A;  1MA9 A;  3JRY A;  3V08 A;  2BXK A;  2BXN A;  3LU8 A;  1TF0 A;  2BXO A;  4HGK A;  3B9L A;  5IJE A;  4ZBR A;  3TDL A;  2BXI A;  1HK4 A;  4G03 A;  1E7B A;  1E78 A;  3LU7 A;  5IFO A;  1E7I A;  5IIH A;  3JQZ A;  5ID7 A;  2XW0 A;  4LUH A;  1E7G A;  1E7C A;  4F5T A;  1AO6 A;  5IJ5 A;  2BXD A;  4JK4 A;  4N0F D;  2BXQ A;  2VDB A;  1E7E A; 
#chains in the Genus database with same CATH topology
 4OTU A;  4FJC B;  3KJL A;  2VUE A;  2XVU A;  2VUF A;  3CX9 A;  2NQO A;  2XSI A;  2DG5 A;  2LXT A;  4L9Q A;  5IIX A;  3FNM A;  2LXS A;  4ZCG A;  3ICX A;  2BXF A;  4L9K A;  5DBY A;  1TXU A;  3MHS B;  3SIU B;  2EFC A;  2LQH A;  4D7X A;  3B9M A;  4J2V A;  2DBW A;  3GA9 L;  1J78 A;  4G04 A;  2BXP A;  3V09 A;  2BXE A;  1HK1 A;  1UOR A;  4PO0 A;  1GNJ A;  4NAW B;  4BY9 C;  1HK5 A;  4LB2 A;  4OT2 A;  4IW2 A;  4OR0 A;  1LNS A;  3SIV B;  4K71 A;  2E0X A;  4ZBQ A;  1E7F A;  3PLA A;  2BX8 A;  1HK2 A;  2XVQ A;  3FWC C;  2AGH B;  4F5S A;  4GG2 A;  2KBZ A;  5BPK A;  3MHH B;  2EFH A;  3H37 A;  4FIP B;  4LA0 A;  3WHQ A;  3ECP A;  1E7A A;  4FK5 B;  1HA2 A;  4MBE C;  4TQ0 A;  1BKE A;  2YDF A;  3A75 A;  1MUH A;  2BXG A;  2Z8I A;  4Z69 A;  3GQU A;  2DBX A;  3WHS A;  4F5V A;  2QMC A;  2XVW A;  3VQI A;  2XVV A;  1E7H A;  1BJ5 A;  4EMX A;  5HOZ A;  1MIW A;  2Z8K A;  4N0U D;  4L8U A;  3UIV A;  4GDL B;  4S1Y A;  4BKE A;  5DQF A;  4TQ1 A;  3W1S A;  3G9K D;  1JNB A;  4IW1 A;  3LU6 A;  5B5T A;  5IIU A;  2DBU A;  1FOU A;  4LUF A;  5GHK A;  2Z8J A;  4F5U A;  4K2C A;  2BXM A;  2BXH A;  1MIV A;  1MUS A;  3KIK A;  4E99 A;  3SQJ A;  5ID9 A;  2BXB A;  2LOQ A;  4GDK B;  5D7G A;  2BXL A;  1VFI A;  1KXP D;  2V36 A;  2QM6 A;  4LB9 A;  4OTT A;  1BM0 A;  2EFD A;  4ZBK A;  3V03 A;  5IJF A;  3A73 A;  5GIN A;  2XW1 A;  4M70 B;  1LOT A;  3NMU A;  2BXC A;  4HGM B;  2DYM A;  1H5W A;  1J7E A;  2BXA A;  4G01 A;  1KW2 A;  5FUO A;  1HK3 A;  1H9Z A;  1N5U A;  2I2Z A;  2KWF A;  2E0Y A;  1O9X A;  4GDX A;  1GNI A;  5GIO A;  2I30 A;  1MA9 A;  2LQI A;  2DYO A;  2NNW A;  3NVM A;  3M99 C;  4ZC6 A;  4C31 B;  3NVI A;  3JRY A;  3V08 A;  2BXK A;  2BXN A;  3LU8 A;  3GQX A;  1TF0 A;  2AJE A;  2BXO A;  4HGK A;  3B9L A;  2QHB A;  5IJE A;  1VZS A;  2K0N A;  4ZBR A;  1NT2 B;  2ROH A;  2GUT A;  4W4U B;  3TDL A;  4DM0 A;  2BXI A;  1SB0 A;  2OT3 A;  1HK4 A;  4I9O A;  2CKX A;  4G03 A;  1E7B A;  1E78 A;  3LU7 A;  4WA6 B;  2OZB B;  2JUH A;  5IFO A;  1E7I A;  5IIH A;  3H3A A;  3JQZ A;  4Z9O A;  5ID7 A;  1MM8 A;  2XW0 A;  4LUH A;  1E7G A;  1MIY A;  4N3Z A;  4DHX B;  4ZUX V;  1KDX A;  2EFE A;  1E7C A;  3WHR A;  4F5T A;  3FWB C;  3NVK A;  1AO6 A;  5IJ5 A;  3BPJ A;  2BXD A;  4JK4 A;  4N0F D;  1IJG A;  2BXQ A;  2VDB A;  2XMO A;  5GIP A;  1E7E A; 
#chains in the Genus database with same CATH homology
 4OTU A;  4FJC B;  3KJL A;  2VUE A;  2XVU A;  2VUF A;  3CX9 A;  2NQO A;  2XSI A;  2DG5 A;  4L9Q A;  5IIX A;  3FNM A;  4ZCG A;  3ICX A;  2BXF A;  4L9K A;  5DBY A;  1TXU A;  3MHS B;  3SIU B;  2EFC A;  3B9M A;  4J2V A;  2DBW A;  3GA9 L;  1J78 A;  4G04 A;  2BXP A;  3V09 A;  2BXE A;  1HK1 A;  1UOR A;  4PO0 A;  1GNJ A;  4NAW B;  4BY9 C;  1HK5 A;  4LB2 A;  4OT2 A;  4IW2 A;  4OR0 A;  1LNS A;  3SIV B;  4K71 A;  2E0X A;  4ZBQ A;  1E7F A;  3PLA A;  2BX8 A;  1HK2 A;  2XVQ A;  3FWC C;  4F5S A;  4GG2 A;  2KBZ A;  5BPK A;  3MHH B;  2EFH A;  3H37 A;  4FIP B;  4LA0 A;  3WHQ A;  1E7A A;  4FK5 B;  1HA2 A;  4MBE C;  4TQ0 A;  1BKE A;  2YDF A;  3A75 A;  2BXG A;  2Z8I A;  4Z69 A;  3GQU A;  2DBX A;  3WHS A;  4F5V A;  2QMC A;  2XVW A;  3VQI A;  2XVV A;  1E7H A;  1BJ5 A;  4EMX A;  5HOZ A;  1MIW A;  2Z8K A;  4N0U D;  4L8U A;  3UIV A;  4GDL B;  4S1Y A;  4BKE A;  5DQF A;  4TQ1 A;  3W1S A;  3G9K D;  1JNB A;  4IW1 A;  3LU6 A;  5B5T A;  5IIU A;  2DBU A;  1FOU A;  4LUF A;  5GHK A;  2Z8J A;  4F5U A;  4K2C A;  2BXM A;  2BXH A;  1MIV A;  3KIK A;  4E99 A;  3SQJ A;  5ID9 A;  2BXB A;  2LOQ A;  4GDK B;  5D7G A;  2BXL A;  1VFI A;  1KXP D;  2V36 A;  2QM6 A;  4LB9 A;  4OTT A;  1BM0 A;  2EFD A;  4ZBK A;  3V03 A;  5IJF A;  3A73 A;  5GIN A;  2XW1 A;  4M70 B;  1LOT A;  3NMU A;  2BXC A;  4HGM B;  2DYM A;  1H5W A;  1J7E A;  2BXA A;  4G01 A;  1KW2 A;  5FUO A;  1HK3 A;  1H9Z A;  1N5U A;  2I2Z A;  2E0Y A;  1O9X A;  4GDX A;  1GNI A;  5GIO A;  2I30 A;  1MA9 A;  2DYO A;  2NNW A;  3NVM A;  3M99 C;  4ZC6 A;  4C31 B;  3NVI A;  3JRY A;  3V08 A;  2BXK A;  2BXN A;  3LU8 A;  3GQX A;  1TF0 A;  2AJE A;  2BXO A;  4HGK A;  3B9L A;  2QHB A;  5IJE A;  1VZS A;  4ZBR A;  1NT2 B;  2ROH A;  4W4U B;  3TDL A;  2BXI A;  2OT3 A;  1HK4 A;  2CKX A;  4G03 A;  1E7B A;  1E78 A;  3LU7 A;  4WA6 B;  2OZB B;  2JUH A;  5IFO A;  1E7I A;  5IIH A;  3H3A A;  3JQZ A;  4Z9O A;  5ID7 A;  2XW0 A;  4LUH A;  1E7G A;  1MIY A;  4N3Z A;  4DHX B;  4ZUX V;  2EFE A;  1E7C A;  3WHR A;  4F5T A;  3FWB C;  3NVK A;  1AO6 A;  5IJ5 A;  2BXD A;  4JK4 A;  4N0F D;  1IJG A;  2BXQ A;  2VDB A;  2XMO A;  5GIP A;  1E7E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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