5IIXA

Crystal structure of equine serum albumin in the presence of 15 mm zinc at ph 6.5
Total Genus 228
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
228
sequence length
581
structure length
577
Chain Sequence
HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 228
structure length 577
sequence length 581
ec nomenclature
pdb deposition date 2016-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA05
4LUHA 4EMXA 3V09A 3CX9A 5IJEA 4PO0A 2BXFA 2BXKA 3SQJA 3V08A 4OT2A 1E78A 2BXBA 2I30A 2BXQA 3JRYA 5ID9A 1N5UA 2VUEA 4E99A 3B9MA 1LOTA 4OR0A 4N0FD 4K71A 1H9ZA 3LU8A 4J2VA 4LB9A 4LUFA 4F5SA 5GHKA 5DQFA 5IJ5A 4Z69A 1TF0A 4G03A 5IIXA 2XVVA 1HK5A 3LU6A 2BXGA 1E7CA 5FUOA 1HK3A 1E7EA 2XVQA 1J7EA 3TDLA 1UORA 1E7AA 1E7IA 5IFOA 2YDFA 1MA9A 1J78A 1E7HA 4IW2A 4ZBQA 4G04A 2BXOA 2BXAA 4BKEA 2BXNA 1BM0A 4F5VA 1HK2A 3JQZA 1HA2A 1HK1A 2BXIA 2XVUA 2I2ZA 2XVWA 1BJ5A 1GNIA 2BXEA 4IW1A 1BKEA 1E7FA 2BXPA 5HOZA 1KW2A 4L8UA 4L9QA 4F5UA 4N0UD 4LB2A 5IJFA 3LU7A 2BXCA 4ZBRA 1E7BA 2XSIA 2BXDA 1GNJA 1E7GA 2BXLA 4HGMB 3UIVA 4HGKA 4JK4A 1O9XA 4LA0A 3A73A 5DBYA 5ID7A 1AO6A 5IIUA 2BXMA 2VDBA 2BX8A 2BXHA 3V03A 2VUFA 4F5TA 2XW1A 2XW0A 4L9KA 1KXPD 3B9LA 1HK4A 4K2CA 4S1YA 5IIHA
chains in the Genus database with same CATH superfamily
4LUHA 4EMXA 4N3ZA 3V09A 2DYOA 3NVIA 1SB0A 3CX9A 5BPKA 2LQHA 5IJEA 2XMOA 4PO0A 2BXFA 2BXKA 3SQJA 5B5TA 3V08A 1MIYA 2DBUA 3BPJA 3NVMA 4OT2A 4BY9C 1E78A 2BXBA 2I30A 2BXQA 4GDLB 2EFCA 3JRYA 4ZUXV 5ID9A 1N5UA 3GA9L 2VUEA 3FWBC 3KJLA 4MBEC 4E99A 4FK5B 2QMCA 3B9MA 1LOTA 4OR0A 2K0NA 1MIWA 4N0FD 2V36A 3M99C 3PLAA 1VFIA 3GQUA 4K71A 1H9ZA 3SIUB 3LU8A 4J2VA 3H37A 4LB9A 4LUFA 4TQ1A 4F5SA 5GHKA 5DQFA 5IJ5A 4Z69A 4GDXA 2DYMA 1TF0A 2JUHA 4G03A 2XVVA 3A75A 5IIXA 5GINA 3ECPA 1MUHA 1HK5A 2CKXA 5GIOA 3LU6A 2BXGA 2KWFA 3NVKA 1MIVA 1E7CA 2ROHA 5FUOA 4FIPB 4ZCGA 2E0YA 1HK3A 1E7EA 1FOUA 2XVQA 4WA6B 4ZBKA 3WHQA 1J7EA 3MHSB 2OZBB 3TDLA 1UORA 1E7AA 1E7IA 3G9KD 3KIKA 5IFOA 2YDFA 1MA9A 4S1YA 2EFDA 3MHHB 3NMUA 1J78A 2AJEA 1E7HA 4IW2A 4ZBQA 4DM0A 4G04A 1LNSA 2BXOA 2BXAA 4BKEA 1VZSA 2Z8IA 2BXNA 1BM0A 4OTUA 4F5VA 1HK2A 3JQZA 4OTTA 1HA2A 1HK1A 2BXIA 2OT3A 2XVUA 4TQ0A 2I2ZA 2NNWA 2DBXA 2XVWA 1KDXA 1BJ5A 1GNIA 1NT2B 2BXEA 3WHSA 2Z8KA 4IW1A 2EFEA 1BKEA 4ZC6A 1E7FA 2BXPA 5HOZA 1KW2A 2DBWA 1TXUA 4L8UA 3WHRA 4L9QA 2KBZA 4N0UD 4F5UA 1MM8A 1MUSA 2EFHA 4LB2A 4C31B 3LU7A 2BXCA 4ZBRA 1IJGA 5IJFA 5GIPA 1E7BA 4W4UB 2XSIA 2BXDA 1GNJA 1E7GA 3FWCC 4NAWB 2BXLA 1JNBA 4HGMB 3UIVA 1H5WA 2NQOA 4HGKA 4GDKB 2QM6A 4JK4A 1O9XA 2Z8JA 4LA0A 3A73A 3H3AA 5DBYA 2AGHB 3FNMA 4I9OA 5ID7A 4M70B 5D7GA 3ICXA 5IIUA 5IIHA 2BXMA 2VDBA 2LQIA 4GG2A 1AO6A 2BX8A 4D7XA 2DG5A 3W1SA 2BXHA 2LOQA 2LXTA 4Z9OA 3VQIA 2QHBA 3SIVB 3V03A 2GUTA 2VUFA 4F5TA 2XW1A 2XW0A 2LXSA 4L9KA 4DHXB 1KXPD 4G01A 3B9LA 4FJCB 1HK4A 4K2CA 2E0XA 3GQXA
chains in the Genus database with same CATH topology
4LUHA 4EMXA 4N3ZA 3V09A 2DYOA 3NVIA 3CX9A 5BPKA 5IJEA 2XMOA 4PO0A 2BXFA 2BXKA 3SQJA 5B5TA 3V08A 1MIYA 2DBUA 3NVMA 4OT2A 4BY9C 1E78A 2BXBA 2I30A 2BXQA 4GDLB 2EFCA 3JRYA 4ZUXV 5ID9A 1N5UA 3GA9L 2VUEA 3FWBC 3KJLA 4MBEC 4E99A 4FK5B 2QMCA 3B9MA 1LOTA 4OR0A 4N0FD 1MIWA 2V36A 3M99C 3PLAA 1VFIA 3GQUA 4K71A 1H9ZA 3SIUB 3LU8A 4J2VA 3H37A 4LB9A 4LUFA 4TQ1A 4F5SA 5GHKA 5DQFA 5IJ5A 4Z69A 4GDXA 2DYMA 1TF0A 2JUHA 4G03A 2XVVA 3A75A 5IIXA 5GINA 1HK5A 2CKXA 5GIOA 3LU6A 2BXGA 3NVKA 1MIVA 1E7CA 2ROHA 5FUOA 4FIPB 4ZCGA 2E0YA 1HK3A 1E7EA 1FOUA 2XVQA 4WA6B 4ZBKA 3WHQA 1J7EA 3MHSB 2OZBB 3TDLA 1UORA 1E7AA 1E7IA 3G9KD 3KIKA 5IFOA 2YDFA 1MA9A 4S1YA 2EFDA 3MHHB 3NMUA 1J78A 2AJEA 1E7HA 4IW2A 4ZBQA 4G04A 1LNSA 2BXOA 2BXAA 4BKEA 1VZSA 2Z8IA 2BXNA 1BM0A 4OTUA 4F5VA 1HK2A 3JQZA 4OTTA 1HA2A 1HK1A 2BXIA 2OT3A 2XVUA 4TQ0A 2I2ZA 2NNWA 2DBXA 2XVWA 1BJ5A 1GNIA 1NT2B 2BXEA 3WHSA 2Z8KA 4IW1A 2EFEA 1BKEA 4ZC6A 1E7FA 2BXPA 5HOZA 1KW2A 2DBWA 1TXUA 4L8UA 3WHRA 4L9QA 2KBZA 4N0UD 4F5UA 2EFHA 4LB2A 4C31B 3LU7A 2BXCA 4ZBRA 1IJGA 5IJFA 5GIPA 1E7BA 4W4UB 2XSIA 2BXDA 1GNJA 1E7GA 3FWCC 4NAWB 2BXLA 1JNBA 4HGMB 3UIVA 1H5WA 2NQOA 4HGKA 4GDKB 2QM6A 4JK4A 1O9XA 2Z8JA 4LA0A 3A73A 3H3AA 5DBYA 3FNMA 5ID7A 4M70B 5D7GA 3ICXA 5IIUA 5IIHA 2BXMA 2VDBA 4GG2A 1AO6A 2BX8A 2DG5A 3W1SA 2BXHA 2LOQA 3VQIA 4Z9OA 2QHBA 3SIVB 3V03A 2VUFA 4F5TA 2XW1A 2XW0A 4L9KA 4DHXB 1KXPD 4G01A 3B9LA 4FJCB 1HK4A 4K2CA 2E0XA 3GQXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LUH A;  4EMX A;  3V09 A;  3CX9 A;  5IJE A;  4PO0 A;  2BXF A;  2BXK A;  3SQJ A;  3V08 A;  4OT2 A;  1E78 A;  2BXB A;  2I30 A;  2BXQ A;  3JRY A;  5ID9 A;  1N5U A;  2VUE A;  4E99 A;  3B9M A;  1LOT A;  4OR0 A;  4N0F D;  4K71 A;  1H9Z A;  3LU8 A;  4J2V A;  4LB9 A;  4LUF A;  4F5S A;  5GHK A;  5DQF A;  5IJ5 A;  4Z69 A;  1TF0 A;  4G03 A;  5IIX A;  2XVV A;  1HK5 A;  3LU6 A;  2BXG A;  1E7C A;  5FUO A;  1HK3 A;  1E7E A;  2XVQ A;  1J7E A;  3TDL A;  1UOR A;  1E7A A;  1E7I A;  5IFO A;  2YDF A;  1MA9 A;  1J78 A;  1E7H A;  4IW2 A;  4ZBQ A;  4G04 A;  2BXO A;  2BXA A;  4BKE A;  2BXN A;  1BM0 A;  4F5V A;  1HK2 A;  3JQZ A;  1HA2 A;  1HK1 A;  2BXI A;  2XVU A;  2I2Z A;  2XVW A;  1BJ5 A;  1GNI A;  2BXE A;  4IW1 A;  1BKE A;  1E7F A;  2BXP A;  5HOZ A;  1KW2 A;  4L8U A;  4L9Q A;  4F5U A;  4N0U D;  4LB2 A;  5IJF A;  3LU7 A;  2BXC A;  4ZBR A;  1E7B A;  2XSI A;  2BXD A;  1GNJ A;  1E7G A;  2BXL A;  4HGM B;  3UIV A;  4HGK A;  4JK4 A;  1O9X A;  4LA0 A;  3A73 A;  5DBY A;  5ID7 A;  1AO6 A;  5IIU A;  2BXM A;  2VDB A;  2BX8 A;  2BXH A;  3V03 A;  2VUF A;  4F5T A;  2XW1 A;  2XW0 A;  4L9K A;  1KXP D;  3B9L A;  1HK4 A;  4K2C A;  4S1Y A;  5IIH A; 
#chains in the Genus database with same CATH topology
 4LUH A;  4EMX A;  4N3Z A;  3V09 A;  2DYO A;  3NVI A;  1SB0 A;  3CX9 A;  5BPK A;  2LQH A;  5IJE A;  2XMO A;  4PO0 A;  2BXF A;  2BXK A;  3SQJ A;  5B5T A;  3V08 A;  1MIY A;  2DBU A;  3BPJ A;  3NVM A;  4OT2 A;  4BY9 C;  1E78 A;  2BXB A;  2I30 A;  2BXQ A;  4GDL B;  2EFC A;  3JRY A;  4ZUX V;  5ID9 A;  1N5U A;  3GA9 L;  2VUE A;  3FWB C;  3KJL A;  4MBE C;  4E99 A;  4FK5 B;  2QMC A;  3B9M A;  1LOT A;  4OR0 A;  2K0N A;  1MIW A;  4N0F D;  2V36 A;  3M99 C;  3PLA A;  1VFI A;  3GQU A;  4K71 A;  1H9Z A;  3SIU B;  3LU8 A;  4J2V A;  3H37 A;  4LB9 A;  4LUF A;  4TQ1 A;  4F5S A;  5GHK A;  5DQF A;  5IJ5 A;  4Z69 A;  4GDX A;  2DYM A;  1TF0 A;  2JUH A;  4G03 A;  2XVV A;  3A75 A;  5IIX A;  5GIN A;  3ECP A;  1MUH A;  1HK5 A;  2CKX A;  5GIO A;  3LU6 A;  2BXG A;  2KWF A;  3NVK A;  1MIV A;  1E7C A;  2ROH A;  5FUO A;  4FIP B;  4ZCG A;  2E0Y A;  1HK3 A;  1E7E A;  1FOU A;  2XVQ A;  4WA6 B;  4ZBK A;  3WHQ A;  1J7E A;  3MHS B;  2OZB B;  3TDL A;  1UOR A;  1E7A A;  1E7I A;  3G9K D;  3KIK A;  5IFO A;  2YDF A;  1MA9 A;  4S1Y A;  2EFD A;  3MHH B;  3NMU A;  1J78 A;  2AJE A;  1E7H A;  4IW2 A;  4ZBQ A;  4DM0 A;  4G04 A;  1LNS A;  2BXO A;  2BXA A;  4BKE A;  1VZS A;  2Z8I A;  2BXN A;  1BM0 A;  4OTU A;  4F5V A;  1HK2 A;  3JQZ A;  4OTT A;  1HA2 A;  1HK1 A;  2BXI A;  2OT3 A;  2XVU A;  4TQ0 A;  2I2Z A;  2NNW A;  2DBX A;  2XVW A;  1KDX A;  1BJ5 A;  1GNI A;  1NT2 B;  2BXE A;  3WHS A;  2Z8K A;  4IW1 A;  2EFE A;  1BKE A;  4ZC6 A;  1E7F A;  2BXP A;  5HOZ A;  1KW2 A;  2DBW A;  1TXU A;  4L8U A;  3WHR A;  4L9Q A;  2KBZ A;  4N0U D;  4F5U A;  1MM8 A;  1MUS A;  2EFH A;  4LB2 A;  4C31 B;  3LU7 A;  2BXC A;  4ZBR A;  1IJG A;  5IJF A;  5GIP A;  1E7B A;  4W4U B;  2XSI A;  2BXD A;  1GNJ A;  1E7G A;  3FWC C;  4NAW B;  2BXL A;  1JNB A;  4HGM B;  3UIV A;  1H5W A;  2NQO A;  4HGK A;  4GDK B;  2QM6 A;  4JK4 A;  1O9X A;  2Z8J A;  4LA0 A;  3A73 A;  3H3A A;  5DBY A;  2AGH B;  3FNM A;  4I9O A;  5ID7 A;  4M70 B;  5D7G A;  3ICX A;  5IIU A;  5IIH A;  2BXM A;  2VDB A;  2LQI A;  4GG2 A;  1AO6 A;  2BX8 A;  4D7X A;  2DG5 A;  3W1S A;  2BXH A;  2LOQ A;  2LXT A;  4Z9O A;  3VQI A;  2QHB A;  3SIV B;  3V03 A;  2GUT A;  2VUF A;  4F5T A;  2XW1 A;  2XW0 A;  2LXS A;  4L9K A;  4DHX B;  1KXP D;  4G01 A;  3B9L A;  4FJC B;  1HK4 A;  4K2C A;  2E0X A;  3GQX A; 
#chains in the Genus database with same CATH homology
 4LUH A;  4EMX A;  4N3Z A;  3V09 A;  2DYO A;  3NVI A;  3CX9 A;  5BPK A;  5IJE A;  2XMO A;  4PO0 A;  2BXF A;  2BXK A;  3SQJ A;  5B5T A;  3V08 A;  1MIY A;  2DBU A;  3NVM A;  4OT2 A;  4BY9 C;  1E78 A;  2BXB A;  2I30 A;  2BXQ A;  4GDL B;  2EFC A;  3JRY A;  4ZUX V;  5ID9 A;  1N5U A;  3GA9 L;  2VUE A;  3FWB C;  3KJL A;  4MBE C;  4E99 A;  4FK5 B;  2QMC A;  3B9M A;  1LOT A;  4OR0 A;  4N0F D;  1MIW A;  2V36 A;  3M99 C;  3PLA A;  1VFI A;  3GQU A;  4K71 A;  1H9Z A;  3SIU B;  3LU8 A;  4J2V A;  3H37 A;  4LB9 A;  4LUF A;  4TQ1 A;  4F5S A;  5GHK A;  5DQF A;  5IJ5 A;  4Z69 A;  4GDX A;  2DYM A;  1TF0 A;  2JUH A;  4G03 A;  2XVV A;  3A75 A;  5IIX A;  5GIN A;  1HK5 A;  2CKX A;  5GIO A;  3LU6 A;  2BXG A;  3NVK A;  1MIV A;  1E7C A;  2ROH A;  5FUO A;  4FIP B;  4ZCG A;  2E0Y A;  1HK3 A;  1E7E A;  1FOU A;  2XVQ A;  4WA6 B;  4ZBK A;  3WHQ A;  1J7E A;  3MHS B;  2OZB B;  3TDL A;  1UOR A;  1E7A A;  1E7I A;  3G9K D;  3KIK A;  5IFO A;  2YDF A;  1MA9 A;  4S1Y A;  2EFD A;  3MHH B;  3NMU A;  1J78 A;  2AJE A;  1E7H A;  4IW2 A;  4ZBQ A;  4G04 A;  1LNS A;  2BXO A;  2BXA A;  4BKE A;  1VZS A;  2Z8I A;  2BXN A;  1BM0 A;  4OTU A;  4F5V A;  1HK2 A;  3JQZ A;  4OTT A;  1HA2 A;  1HK1 A;  2BXI A;  2OT3 A;  2XVU A;  4TQ0 A;  2I2Z A;  2NNW A;  2DBX A;  2XVW A;  1BJ5 A;  1GNI A;  1NT2 B;  2BXE A;  3WHS A;  2Z8K A;  4IW1 A;  2EFE A;  1BKE A;  4ZC6 A;  1E7F A;  2BXP A;  5HOZ A;  1KW2 A;  2DBW A;  1TXU A;  4L8U A;  3WHR A;  4L9Q A;  2KBZ A;  4N0U D;  4F5U A;  2EFH A;  4LB2 A;  4C31 B;  3LU7 A;  2BXC A;  4ZBR A;  1IJG A;  5IJF A;  5GIP A;  1E7B A;  4W4U B;  2XSI A;  2BXD A;  1GNJ A;  1E7G A;  3FWC C;  4NAW B;  2BXL A;  1JNB A;  4HGM B;  3UIV A;  1H5W A;  2NQO A;  4HGK A;  4GDK B;  2QM6 A;  4JK4 A;  1O9X A;  2Z8J A;  4LA0 A;  3A73 A;  3H3A A;  5DBY A;  3FNM A;  5ID7 A;  4M70 B;  5D7G A;  3ICX A;  5IIU A;  5IIH A;  2BXM A;  2VDB A;  4GG2 A;  1AO6 A;  2BX8 A;  2DG5 A;  3W1S A;  2BXH A;  2LOQ A;  3VQI A;  4Z9O A;  2QHB A;  3SIV B;  3V03 A;  2VUF A;  4F5T A;  2XW1 A;  2XW0 A;  4L9K A;  4DHX B;  1KXP D;  4G01 A;  3B9L A;  4FJC B;  1HK4 A;  4K2C A;  2E0X A;  3GQX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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