5KN8A

Muty n-terminal domain in complex with undamaged dna
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
222
structure length
222
Chain Sequence
FPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRVETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Geobacillus stearothermophilus
molecule keywords Adenine DNA glycosylase
total genus 87
structure length 222
sequence length 222
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2016-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5kn8A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 5kn8A01
2NOBA 3CWTA 4AIAA 4EJYA 5AN4A 5KN8A 1YQMA 3CWUA 3S6IA 1KG6A 4OFAA 4OFHA 3F0ZA 4EVVA 4EW0A 2NOFA 1ORPA 1KEAA 1WEGA 1KG7A 4EW4A 1ORNA 3CW7A 1MPGA 3CVTA 4E9EA 4E9FA 1VRLA 1M3QA 1RRQA 1XQPA 1P59A 3CWSA 4EJZA 1XQOA 4B22A 1RRSA 4UNFA 3KNTA 1PU6A 1NKUA 1MUDA 2ABKA 4DK9A 2NOLA 1FN7A 2OFKA 3IHOA 4YPHA 1MUNA 1KO9A 4EA4A 3OH6A 2JG6A 3I0XA 3D4VA 4B24A 5DPKA 3CWAA 1KG4A 3FHFA 3I0WA 5CHZA 4AI5A 3G0QA 1HU0A 3CVSA 1YQRA 1KQJA 2YG8A 3OH9A 1YQLA 1WEIA 2JHNA 4YOQA 1WEFA 1P7MA 3FHGA 1LWVA 3F10A 4B21A 4E9HA 2NOHA 3N5NX 1KG5A 3OGDA 4EA5A 1PU7A 1YQKA 1KG3A 1DIZA 2H56A 2OFIA 2JHJA 1NGNA 1LMZA 5KN9A 1N39A 2NOEA 2XHIA 1MUYA 3N0UA 1LWYA 2YG9A 1N3CA 4UOBA 1EBMA 4OFEA 3FSPA 2NOZA 4PIIA 4AI4A 4B23A 1KG2A 1M3HA 2I5WA 1PVSA 4HSBA 4E9GA 1XG7A 4YPRA 3IH7A 2NOIA 3KTUA 1PU8A 1LWWA 1N3AA
chains in the Genus database with same CATH superfamily
2NOBA 3CWTA 4AIAA 4EJYA 5AN4A 5KN8A 3L2QA 1YQMA 3CWUA 3S6IA 3OS0A 1KG6A 4OFAA 4OFHA 3F0ZA 4EVVA 4EW0A 4BDZA 2NOFA 1ORPA 1KEAA 1WEGA 1KG7A 4EW4A 1ORNA 3CW7A 1MPGA 3OYIA 3CVTA 4E9EA 3OYCA 4E9FA 3OS2A 1VRLA 3OYBA 3OS1A 3OYFA 5FRNA 3OYEA 4E7HA 4BE0A 1M3QA 3NNQA 4E7KA 3OY9A 1RRQA 1XQPA 3S3MA 1P59A 3CWSA 4EJZA 1XQOA 3OYJA 2W04A 4B22A 1RRSA 4UNFA 3L2VA 3KNTA 1PU6A 1NKUA 1MUDA 4E7LA 2ABKA 4DK9A 4BE1A 4NZGA 2NOLA 1FN7A 2OFKA 3IHOA 4YPHA 4BDYA 3OYKA 3OYMA 1MUNA 1KO9A 4ZTFA 4EA4A 3OH6A 2JG6A 3LCNA 4E7IA 3I0XA 3D4VA 4B24A 5DPKA 3CWAA 1KG4A 3FHFA 3I0WA 3OYAA 5CHZA 3L2RA 4AI5A 3G0QA 1HU0A 3CVSA 1YQRA 1KQJA 2YG8A 3OH9A 3S3OA 1YQLA 1WEIA 3OYLA 2JHNA 4E7JA 4YOQA 1WEFA 1P7MA 2W03A 3FHGA 1LWVA 3F10A 4B21A 4E9HA 2NOHA 3N5NX 1KG5A 3S3NA 5FROA 3OGDA 3OYHA 4EA5A 1PU7A 1U84A 3R2XC 1YQKA 1KG3A 1DIZA 4BACA 2H56A 2OFIA 2JHJA 3OYDA 1NGNA 1LMZA 5KN9A 1N39A 2NOEA 5FRMA 2XHIA 1MUYA 3N0UA 2JPSA 1LWYA 2YG9A 1N3CA 4UOBA 1EBMA 3OYGA 4OFEA 3FSPA 2NOZA 4PIIA 4AI4A 3L2UA 4B23A 1KG2A 3L2WA 1M3HA 2I5WA 1PVSA 4HSBA 3OYNA 3VW4A 4E9GA 1XG7A 4IKFA 4YPRA 2V75A 4BE2A 3IH7A 4ZTJA 2NOIA 3KTUA 1PU8A 1LWWA 1N3AA
chains in the Genus database with same CATH topology
2NOBA 3CWTA 4AIAA 4EJYA 5AN4A 5KN8A 1YQMA 3CWUA 3S6IA 1KG6A 4OFAA 4OFHA 3F0ZA 4EVVA 4EW0A 2NOFA 1ORPA 1KEAA 1WEGA 1KG7A 4EW4A 1ORNA 3CW7A 1MPGA 3CVTA 4E9EA 4E9FA 1VRLA 1M3QA 1RRQA 1XQPA 1P59A 3CWSA 4EJZA 1XQOA 4B22A 1RRSA 4UNFA 3KNTA 1PU6A 1NKUA 1MUDA 2ABKA 4DK9A 2NOLA 1FN7A 2OFKA 3IHOA 4YPHA 1MUNA 1KO9A 4EA4A 3OH6A 2JG6A 3I0XA 3D4VA 4B24A 5DPKA 3CWAA 1KG4A 3FHFA 3I0WA 5CHZA 4AI5A 3G0QA 1HU0A 3CVSA 1YQRA 1KQJA 2YG8A 3OH9A 1YQLA 1WEIA 2JHNA 4YOQA 1WEFA 1P7MA 3FHGA 1LWVA 3F10A 4B21A 4E9HA 2NOHA 3N5NX 1KG5A 3OGDA 4EA5A 1PU7A 1YQKA 1KG3A 1DIZA 2H56A 2OFIA 2JHJA 1NGNA 1LMZA 5KN9A 1N39A 2NOEA 2XHIA 1MUYA 3N0UA 1LWYA 2YG9A 1N3CA 4UOBA 1EBMA 4OFEA 3FSPA 2NOZA 4PIIA 4AI4A 4B23A 1KG2A 1M3HA 2I5WA 1PVSA 4HSBA 4E9GA 1XG7A 4YPRA 3IH7A 2NOIA 3KTUA 1PU8A 1LWWA 1N3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NOB A;  3CWT A;  4AIA A;  4EJY A;  5AN4 A;  5KN8 A;  1YQM A;  3CWU A;  3S6I A;  1KG6 A;  4OFA A;  4OFH A;  3F0Z A;  4EVV A;  4EW0 A;  2NOF A;  1ORP A;  1KEA A;  1WEG A;  1KG7 A;  4EW4 A;  1ORN A;  3CW7 A;  1MPG A;  3CVT A;  4E9E A;  4E9F A;  1VRL A;  1M3Q A;  1RRQ A;  1XQP A;  1P59 A;  3CWS A;  4EJZ A;  1XQO A;  4B22 A;  1RRS A;  4UNF A;  3KNT A;  1PU6 A;  1NKU A;  1MUD A;  2ABK A;  4DK9 A;  2NOL A;  1FN7 A;  2OFK A;  3IHO A;  4YPH A;  1MUN A;  1KO9 A;  4EA4 A;  3OH6 A;  2JG6 A;  3I0X A;  3D4V A;  4B24 A;  5DPK A;  3CWA A;  1KG4 A;  3FHF A;  3I0W A;  5CHZ A;  4AI5 A;  3G0Q A;  1HU0 A;  3CVS A;  1YQR A;  1KQJ A;  2YG8 A;  3OH9 A;  1YQL A;  1WEI A;  2JHN A;  4YOQ A;  1WEF A;  1P7M A;  3FHG A;  1LWV A;  3F10 A;  4B21 A;  4E9H A;  2NOH A;  3N5N X;  1KG5 A;  3OGD A;  4EA5 A;  1PU7 A;  1YQK A;  1KG3 A;  1DIZ A;  2H56 A;  2OFI A;  2JHJ A;  1NGN A;  1LMZ A;  5KN9 A;  1N39 A;  2NOE A;  2XHI A;  1MUY A;  3N0U A;  1LWY A;  2YG9 A;  1N3C A;  4UOB A;  1EBM A;  4OFE A;  3FSP A;  2NOZ A;  4PII A;  4AI4 A;  4B23 A;  1KG2 A;  1M3H A;  2I5W A;  1PVS A;  4HSB A;  4E9G A;  1XG7 A;  4YPR A;  3IH7 A;  2NOI A;  3KTU A;  1PU8 A;  1LWW A;  1N3A A; 
#chains in the Genus database with same CATH topology
 2NOB A;  3CWT A;  4AIA A;  4EJY A;  5AN4 A;  5KN8 A;  3L2Q A;  1YQM A;  3CWU A;  3S6I A;  3OS0 A;  1KG6 A;  4OFA A;  4OFH A;  3F0Z A;  4EVV A;  4EW0 A;  4BDZ A;  2NOF A;  1ORP A;  1KEA A;  1WEG A;  1KG7 A;  4EW4 A;  1ORN A;  3CW7 A;  1MPG A;  3OYI A;  3CVT A;  4E9E A;  3OYC A;  4E9F A;  3OS2 A;  1VRL A;  3OYB A;  3OS1 A;  3OYF A;  5FRN A;  3OYE A;  4E7H A;  4BE0 A;  1M3Q A;  3NNQ A;  4E7K A;  3OY9 A;  1RRQ A;  1XQP A;  3S3M A;  1P59 A;  3CWS A;  4EJZ A;  1XQO A;  3OYJ A;  2W04 A;  4B22 A;  1RRS A;  4UNF A;  3L2V A;  3KNT A;  1PU6 A;  1NKU A;  1MUD A;  4E7L A;  2ABK A;  4DK9 A;  4BE1 A;  4NZG A;  2NOL A;  1FN7 A;  2OFK A;  3IHO A;  4YPH A;  4BDY A;  3OYK A;  3OYM A;  1MUN A;  1KO9 A;  4ZTF A;  4EA4 A;  3OH6 A;  2JG6 A;  3LCN A;  4E7I A;  3I0X A;  3D4V A;  4B24 A;  5DPK A;  3CWA A;  1KG4 A;  3FHF A;  3I0W A;  3OYA A;  5CHZ A;  3L2R A;  4AI5 A;  3G0Q A;  1HU0 A;  3CVS A;  1YQR A;  1KQJ A;  2YG8 A;  3OH9 A;  3S3O A;  1YQL A;  1WEI A;  3OYL A;  2JHN A;  4E7J A;  4YOQ A;  1WEF A;  1P7M A;  2W03 A;  3FHG A;  1LWV A;  3F10 A;  4B21 A;  4E9H A;  2NOH A;  3N5N X;  1KG5 A;  3S3N A;  5FRO A;  3OGD A;  3OYH A;  4EA5 A;  1PU7 A;  1U84 A;  3R2X C;  1YQK A;  1KG3 A;  1DIZ A;  4BAC A;  2H56 A;  2OFI A;  2JHJ A;  3OYD A;  1NGN A;  1LMZ A;  5KN9 A;  1N39 A;  2NOE A;  5FRM A;  2XHI A;  1MUY A;  3N0U A;  2JPS A;  1LWY A;  2YG9 A;  1N3C A;  4UOB A;  1EBM A;  3OYG A;  4OFE A;  3FSP A;  2NOZ A;  4PII A;  4AI4 A;  3L2U A;  4B23 A;  1KG2 A;  3L2W A;  1M3H A;  2I5W A;  1PVS A;  4HSB A;  3OYN A;  3VW4 A;  4E9G A;  1XG7 A;  4IKF A;  4YPR A;  2V75 A;  4BE2 A;  3IH7 A;  4ZTJ A;  2NOI A;  3KTU A;  1PU8 A;  1LWW A;  1N3A A; 
#chains in the Genus database with same CATH homology
 2NOB A;  3CWT A;  4AIA A;  4EJY A;  5AN4 A;  5KN8 A;  1YQM A;  3CWU A;  3S6I A;  1KG6 A;  4OFA A;  4OFH A;  3F0Z A;  4EVV A;  4EW0 A;  2NOF A;  1ORP A;  1KEA A;  1WEG A;  1KG7 A;  4EW4 A;  1ORN A;  3CW7 A;  1MPG A;  3CVT A;  4E9E A;  4E9F A;  1VRL A;  1M3Q A;  1RRQ A;  1XQP A;  1P59 A;  3CWS A;  4EJZ A;  1XQO A;  4B22 A;  1RRS A;  4UNF A;  3KNT A;  1PU6 A;  1NKU A;  1MUD A;  2ABK A;  4DK9 A;  2NOL A;  1FN7 A;  2OFK A;  3IHO A;  4YPH A;  1MUN A;  1KO9 A;  4EA4 A;  3OH6 A;  2JG6 A;  3I0X A;  3D4V A;  4B24 A;  5DPK A;  3CWA A;  1KG4 A;  3FHF A;  3I0W A;  5CHZ A;  4AI5 A;  3G0Q A;  1HU0 A;  3CVS A;  1YQR A;  1KQJ A;  2YG8 A;  3OH9 A;  1YQL A;  1WEI A;  2JHN A;  4YOQ A;  1WEF A;  1P7M A;  3FHG A;  1LWV A;  3F10 A;  4B21 A;  4E9H A;  2NOH A;  3N5N X;  1KG5 A;  3OGD A;  4EA5 A;  1PU7 A;  1YQK A;  1KG3 A;  1DIZ A;  2H56 A;  2OFI A;  2JHJ A;  1NGN A;  1LMZ A;  5KN9 A;  1N39 A;  2NOE A;  2XHI A;  1MUY A;  3N0U A;  1LWY A;  2YG9 A;  1N3C A;  4UOB A;  1EBM A;  4OFE A;  3FSP A;  2NOZ A;  4PII A;  4AI4 A;  4B23 A;  1KG2 A;  1M3H A;  2I5W A;  1PVS A;  4HSB A;  4E9G A;  1XG7 A;  4YPR A;  3IH7 A;  2NOI A;  3KTU A;  1PU8 A;  1LWW A;  1N3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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