5KN9A

Muty n-terminal domain in complex with dna containing an intrahelical oxog:a base-pair
Total Genus 80
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
80
sequence length
222
structure length
222
Chain Sequence
FPAREFQRDLLDWFARERRDLPWRKDRDPYKVWVSEVMLQQTRYETVIPYFEQFIDRFPTLEALADADEDEVLKAWEGLGYYSRVRNLHAAVKEVKTRYGGKVPDDPDEFSRLKGVGPYTVGAVLSLAYGVPEPAVNGNVMRVLSRLFLVTDDIAKCSTRKRFEQIVREIMAYENPGAFNEALIELGALVCTPRRPSCLLCPVQAYCQAFAEGVAEELPVKM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism geobacillus stearothermophilus
molecule keywords Adenine DNA glycosylase
total genus 80
structure length 222
sequence length 222
ec nomenclature ec 3.2.2.31: Adenine glycosylase.
pdb deposition date 2016-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00633 HHH Helix-hairpin-helix motif
A PF00730 HhH-GPD HhH-GPD superfamily base excision DNA repair protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 5kn9A02
1.10.1670.10 Mainly Alpha Orthogonal Bundle Endonuclease Iii, domain 2 Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) 5kn9A01
4UOBA 3KNTA 1P59A 3G0QA 4HSBA 1YQKA 1KG2A 2NOHA 1M3QA 1YQMA 4YOQA 2I5WA 4YPHA 1ORPA 2JHNA 1RRQA 1KG6A 4OFHA 1WEFA 4EA4A 2YG8A 3CWAA 4EW0A 3CWSA 1KQJA 1KG7A 4B22A 1LWVA 1NGNA 4AIAA 2H56A 4DK9A 3CWUA 2OFKA 3CVSA 4OFEA 1N3CA 1N39A 3I0WA 1P7MA 1KG5A 4B21A 4EA5A 5KN9A 1XQOA 4UNFA 2YG9A 4YPRA 1KEAA 1YQRA 3CW7A 3S6IA 3FHGA 3KTUA 2JHJA 1YQLA 3IH7A 4PIIA 1MPGA 1LMZA 3OH9A 1XG7A 2ABKA 3N0UA 2NOIA 2NOBA 4B23A 3F10A 3IHOA 1N3AA 4E9HA 3I0XA 2NOEA 1MUYA 1PVSA 4AI4A 3N5NX 1PU8A 1XQPA 1PU7A 2NOFA 4OFAA 2NOZA 3D4VA 1LWYA 1KO9A 1ORNA 2NOLA 3FHFA 1VRLA 4B24A 4EW4A 4EJYA 3FSPA 4AI5A 2OFIA 1RRSA 1LWWA 4E9GA 4EJZA 5KN8A 4E9FA 3OGDA 1FN7A 1HU0A 3CWTA 2XHIA 5AN4A 4EVVA 1DIZA 1MUDA 3OH6A 1NKUA 1MUNA 5DPKA 1M3HA 4E9EA 2JG6A 5CHZA 3F0ZA 1PU6A 1EBMA 3CVTA 1WEIA 1KG3A 1WEGA 1KG4A
chains in the Genus database with same CATH superfamily
4UOBA 3KNTA 4IKFA 3S3MA 1P59A 3OYNA 4NZGA 3NNQA 3G0QA 5FRMA 4HSBA 1YQKA 3OYAA 1KG2A 2NOHA 1M3QA 1YQMA 4YOQA 4ZTFA 2I5WA 4YPHA 1ORPA 2JHNA 4BDZA 1RRQA 1KG6A 4OFHA 1WEFA 4EA4A 3OYBA 3OYJA 2YG8A 3OYDA 3CWAA 4EW0A 3CWSA 4E7KA 1KQJA 1KG7A 4B22A 1LWVA 1NGNA 4AIAA 2H56A 3L2RA 4DK9A 3CWUA 2OFKA 5FROA 3CVSA 4OFEA 1N3CA 1N39A 3L2VA 3I0WA 1P7MA 1KG5A 4B21A 4EA5A 5KN9A 1XQOA 4UNFA 2YG9A 4YPRA 1KEAA 3OYFA 1YQRA 3CW7A 3S3OA 3S6IA 4E7JA 4BACA 3FHGA 3KTUA 3L2UA 2JHJA 1YQLA 3IH7A 4PIIA 3OYGA 1MPGA 1LMZA 3OYMA 3OH9A 1XG7A 2ABKA 3N0UA 2V75A 2NOIA 2NOBA 4B23A 3F10A 2JPSA 3L2QA 3IHOA 1N3AA 3OYKA 4E9HA 3I0XA 3OYCA 2NOEA 1MUYA 1PVSA 4AI4A 3N5NX 1PU8A 1XQPA 1PU7A 3OS2A 2NOFA 3R2XC 4OFAA 3OYIA 2NOZA 4E7LA 4BDYA 3D4VA 3OS1A 1LWYA 1KO9A 4E7IA 1ORNA 2NOLA 3S3NA 3FHFA 1VRLA 4B24A 3OS0A 4EW4A 3L2WA 4EJYA 2W04A 4AI5A 3FSPA 2W03A 2OFIA 1RRSA 1LWWA 3OYHA 4E9GA 4EJZA 5KN8A 3OYEA 4E7HA 4E9FA 3OGDA 4ZTJA 1FN7A 1HU0A 3CWTA 2XHIA 5AN4A 4EVVA 1DIZA 1MUDA 3OH6A 4BE0A 1NKUA 1MUNA 3VW4A 5DPKA 1M3HA 4E9EA 2JG6A 5CHZA 3F0ZA 1PU6A 3OY9A 1EBMA 5FRNA 4BE2A 3CVTA 1WEIA 4BE1A 1KG3A 3OYLA 1U84A 1WEGA 3LCNA 1KG4A
chains in the Genus database with same CATH topology
4UOBA 3KNTA 1P59A 3G0QA 4HSBA 1YQKA 1KG2A 2NOHA 1M3QA 1YQMA 4YOQA 2I5WA 4YPHA 1ORPA 2JHNA 1RRQA 1KG6A 4OFHA 1WEFA 4EA4A 2YG8A 3CWAA 4EW0A 3CWSA 1KQJA 1KG7A 4B22A 1LWVA 1NGNA 4AIAA 2H56A 4DK9A 3CWUA 2OFKA 3CVSA 4OFEA 1N3CA 1N39A 3I0WA 1P7MA 1KG5A 4B21A 4EA5A 5KN9A 1XQOA 4UNFA 2YG9A 4YPRA 1KEAA 1YQRA 3CW7A 3S6IA 3FHGA 3KTUA 2JHJA 1YQLA 3IH7A 4PIIA 1MPGA 1LMZA 3OH9A 1XG7A 2ABKA 3N0UA 2NOIA 2NOBA 4B23A 3F10A 3IHOA 1N3AA 4E9HA 3I0XA 2NOEA 1MUYA 1PVSA 4AI4A 3N5NX 1PU8A 1XQPA 1PU7A 2NOFA 4OFAA 2NOZA 3D4VA 1LWYA 1KO9A 1ORNA 2NOLA 3FHFA 1VRLA 4B24A 4EW4A 4EJYA 3FSPA 4AI5A 2OFIA 1RRSA 1LWWA 4E9GA 4EJZA 5KN8A 4E9FA 3OGDA 1FN7A 1HU0A 3CWTA 2XHIA 5AN4A 4EVVA 1DIZA 1MUDA 3OH6A 1NKUA 1MUNA 5DPKA 1M3HA 4E9EA 2JG6A 5CHZA 3F0ZA 1PU6A 1EBMA 3CVTA 1WEIA 1KG3A 1WEGA 1KG4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UOB A;  3KNT A;  1P59 A;  3G0Q A;  4HSB A;  1YQK A;  1KG2 A;  2NOH A;  1M3Q A;  1YQM A;  4YOQ A;  2I5W A;  4YPH A;  1ORP A;  2JHN A;  1RRQ A;  1KG6 A;  4OFH A;  1WEF A;  4EA4 A;  2YG8 A;  3CWA A;  4EW0 A;  3CWS A;  1KQJ A;  1KG7 A;  4B22 A;  1LWV A;  1NGN A;  4AIA A;  2H56 A;  4DK9 A;  3CWU A;  2OFK A;  3CVS A;  4OFE A;  1N3C A;  1N39 A;  3I0W A;  1P7M A;  1KG5 A;  4B21 A;  4EA5 A;  5KN9 A;  1XQO A;  4UNF A;  2YG9 A;  4YPR A;  1KEA A;  1YQR A;  3CW7 A;  3S6I A;  3FHG A;  3KTU A;  2JHJ A;  1YQL A;  3IH7 A;  4PII A;  1MPG A;  1LMZ A;  3OH9 A;  1XG7 A;  2ABK A;  3N0U A;  2NOI A;  2NOB A;  4B23 A;  3F10 A;  3IHO A;  1N3A A;  4E9H A;  3I0X A;  2NOE A;  1MUY A;  1PVS A;  4AI4 A;  3N5N X;  1PU8 A;  1XQP A;  1PU7 A;  2NOF A;  4OFA A;  2NOZ A;  3D4V A;  1LWY A;  1KO9 A;  1ORN A;  2NOL A;  3FHF A;  1VRL A;  4B24 A;  4EW4 A;  4EJY A;  3FSP A;  4AI5 A;  2OFI A;  1RRS A;  1LWW A;  4E9G A;  4EJZ A;  5KN8 A;  4E9F A;  3OGD A;  1FN7 A;  1HU0 A;  3CWT A;  2XHI A;  5AN4 A;  4EVV A;  1DIZ A;  1MUD A;  3OH6 A;  1NKU A;  1MUN A;  5DPK A;  1M3H A;  4E9E A;  2JG6 A;  5CHZ A;  3F0Z A;  1PU6 A;  1EBM A;  3CVT A;  1WEI A;  1KG3 A;  1WEG A;  1KG4 A; 
#chains in the Genus database with same CATH topology
 4UOB A;  3KNT A;  4IKF A;  3S3M A;  1P59 A;  3OYN A;  4NZG A;  3NNQ A;  3G0Q A;  5FRM A;  4HSB A;  1YQK A;  3OYA A;  1KG2 A;  2NOH A;  1M3Q A;  1YQM A;  4YOQ A;  4ZTF A;  2I5W A;  4YPH A;  1ORP A;  2JHN A;  4BDZ A;  1RRQ A;  1KG6 A;  4OFH A;  1WEF A;  4EA4 A;  3OYB A;  3OYJ A;  2YG8 A;  3OYD A;  3CWA A;  4EW0 A;  3CWS A;  4E7K A;  1KQJ A;  1KG7 A;  4B22 A;  1LWV A;  1NGN A;  4AIA A;  2H56 A;  3L2R A;  4DK9 A;  3CWU A;  2OFK A;  5FRO A;  3CVS A;  4OFE A;  1N3C A;  1N39 A;  3L2V A;  3I0W A;  1P7M A;  1KG5 A;  4B21 A;  4EA5 A;  5KN9 A;  1XQO A;  4UNF A;  2YG9 A;  4YPR A;  1KEA A;  3OYF A;  1YQR A;  3CW7 A;  3S3O A;  3S6I A;  4E7J A;  4BAC A;  3FHG A;  3KTU A;  3L2U A;  2JHJ A;  1YQL A;  3IH7 A;  4PII A;  3OYG A;  1MPG A;  1LMZ A;  3OYM A;  3OH9 A;  1XG7 A;  2ABK A;  3N0U A;  2V75 A;  2NOI A;  2NOB A;  4B23 A;  3F10 A;  2JPS A;  3L2Q A;  3IHO A;  1N3A A;  3OYK A;  4E9H A;  3I0X A;  3OYC A;  2NOE A;  1MUY A;  1PVS A;  4AI4 A;  3N5N X;  1PU8 A;  1XQP A;  1PU7 A;  3OS2 A;  2NOF A;  3R2X C;  4OFA A;  3OYI A;  2NOZ A;  4E7L A;  4BDY A;  3D4V A;  3OS1 A;  1LWY A;  1KO9 A;  4E7I A;  1ORN A;  2NOL A;  3S3N A;  3FHF A;  1VRL A;  4B24 A;  3OS0 A;  4EW4 A;  3L2W A;  4EJY A;  2W04 A;  4AI5 A;  3FSP A;  2W03 A;  2OFI A;  1RRS A;  1LWW A;  3OYH A;  4E9G A;  4EJZ A;  5KN8 A;  3OYE A;  4E7H A;  4E9F A;  3OGD A;  4ZTJ A;  1FN7 A;  1HU0 A;  3CWT A;  2XHI A;  5AN4 A;  4EVV A;  1DIZ A;  1MUD A;  3OH6 A;  4BE0 A;  1NKU A;  1MUN A;  3VW4 A;  5DPK A;  1M3H A;  4E9E A;  2JG6 A;  5CHZ A;  3F0Z A;  1PU6 A;  3OY9 A;  1EBM A;  5FRN A;  4BE2 A;  3CVT A;  1WEI A;  4BE1 A;  1KG3 A;  3OYL A;  1U84 A;  1WEG A;  3LCN A;  1KG4 A; 
#chains in the Genus database with same CATH homology
 4UOB A;  3KNT A;  1P59 A;  3G0Q A;  4HSB A;  1YQK A;  1KG2 A;  2NOH A;  1M3Q A;  1YQM A;  4YOQ A;  2I5W A;  4YPH A;  1ORP A;  2JHN A;  1RRQ A;  1KG6 A;  4OFH A;  1WEF A;  4EA4 A;  2YG8 A;  3CWA A;  4EW0 A;  3CWS A;  1KQJ A;  1KG7 A;  4B22 A;  1LWV A;  1NGN A;  4AIA A;  2H56 A;  4DK9 A;  3CWU A;  2OFK A;  3CVS A;  4OFE A;  1N3C A;  1N39 A;  3I0W A;  1P7M A;  1KG5 A;  4B21 A;  4EA5 A;  5KN9 A;  1XQO A;  4UNF A;  2YG9 A;  4YPR A;  1KEA A;  1YQR A;  3CW7 A;  3S6I A;  3FHG A;  3KTU A;  2JHJ A;  1YQL A;  3IH7 A;  4PII A;  1MPG A;  1LMZ A;  3OH9 A;  1XG7 A;  2ABK A;  3N0U A;  2NOI A;  2NOB A;  4B23 A;  3F10 A;  3IHO A;  1N3A A;  4E9H A;  3I0X A;  2NOE A;  1MUY A;  1PVS A;  4AI4 A;  3N5N X;  1PU8 A;  1XQP A;  1PU7 A;  2NOF A;  4OFA A;  2NOZ A;  3D4V A;  1LWY A;  1KO9 A;  1ORN A;  2NOL A;  3FHF A;  1VRL A;  4B24 A;  4EW4 A;  4EJY A;  3FSP A;  4AI5 A;  2OFI A;  1RRS A;  1LWW A;  4E9G A;  4EJZ A;  5KN8 A;  4E9F A;  3OGD A;  1FN7 A;  1HU0 A;  3CWT A;  2XHI A;  5AN4 A;  4EVV A;  1DIZ A;  1MUD A;  3OH6 A;  1NKU A;  1MUN A;  5DPK A;  1M3H A;  4E9E A;  2JG6 A;  5CHZ A;  3F0Z A;  1PU6 A;  1EBM A;  3CVT A;  1WEI A;  1KG3 A;  1WEG A;  1KG4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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