5DQFA

Horse serum albumin (esa) in complex with cetirizine
Total Genus 238
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
238
sequence length
580
structure length
580
Chain Sequence
KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug binding site.
pubmed doi rcsb
molecule keywords Serum albumin
molecule tags Transport protein
total genus 238
structure length 580
sequence length 580
ec nomenclature
pdb deposition date 2015-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dqfA05
1BJ5A 3TDLA 2XW0A 2XSIA 2BXAA 4OR0A 3CX9A 4OT2A 3UIVA 3SQJA 2BXBA 4F5SA 1E7BA 2BXPA 3JRYA 2BXQA 1BKEA 2VUEA 2VDBA 4IW1A 2XVWA 5IIXA 4K71A 4LA0A 4LB9A 5DBYA 1J7EA 1E7EA 4L8UA 1HA2A 2BXFA 2BXOA 2BXHA 4PO0A 1HK4A 3A73A 1E78A 1E7FA 1N5UA 4EMXA 2YDFA 4HGKA 2I30A 5ID9A 1TF0A 4N0UD 1E7HA 3LU6A 2BXKA 3B9MA 3V09A 5IJFA 4S1YA 4ZBRA 1J78A 2XVQA 2BXGA 2BXMA 4JK4A 4HGMB 5IJEA 1O9XA 4IW2A 1AO6A 5IIUA 1BM0A 2VUFA 4LB2A 4ZBQA 4L9QA 1GNJA 3B9LA 1HK5A 4LUFA 4N0FD 2BXIA 4F5VA 4G04A 4E99A 1HK1A 3LU8A 4K2CA 5IIHA 1UORA 5HOZA 1E7CA 4G03A 4J2VA 4F5UA 2BXNA 5FUOA 3JQZA 1HK3A 2BXLA 2BXCA 5DQFA 1H9ZA 4F5TA 1E7AA 1E7IA 2BXEA 2XVVA 1GNIA 5IFOA 4Z69A 4BKEA 1LOTA 1E7GA 5GHKA 4LUHA 2BX8A 3LU7A 2XW1A 1KXPD 5ID7A 1MA9A 4L9KA 1HK2A 1KW2A 2XVUA 2I2ZA 2BXDA 3V08A 3V03A 5IJ5A
chains in the Genus database with same CATH superfamily
4G01A 1VFIA 1BJ5A 3TDLA 1H5WA 2XW0A 3M99C 2XSIA 2BXAA 1MM8A 4BY9C 4OR0A 2KWFA 4ZUXV 3CX9A 4OT2A 3UIVA 1FOUA 4N3ZA 3SQJA 2BXBA 4F5SA 2DYOA 2LXSA 1E7BA 3WHRA 3ICXA 3VQIA 4OTTA 2BXPA 3JRYA 2BXQA 1BKEA 4GG2A 2VUEA 4GDKB 2VDBA 4IW1A 2DYMA 2XVWA 1MIVA 2DBWA 3GQXA 5IIXA 4K71A 1NT2B 2Z8JA 5GINA 3NMUA 4LA0A 4LB9A 5DBYA 1J7EA 2EFHA 4OTUA 1E7EA 4L8UA 5D7GA 4M70B 1HA2A 2AGHB 4Z9OA 3NVIA 4ZC6A 4TQ0A 1MIWA 2BXFA 2BXOA 2QMCA 2BXHA 4NAWB 4PO0A 1VZSA 2EFDA 1HK4A 2LQIA 3A73A 3NVMA 1E78A 1E7FA 1N5UA 3WHSA 3FWBC 3ECPA 4EMXA 5GIPA 2KBZA 2YDFA 4HGKA 2I30A 2K0NA 5ID9A 1TF0A 4N0UD 1E7HA 3LU6A 2BXKA 3B9MA 4FK5B 3V09A 4S1YA 4DHXB 5IJFA 4ZBRA 3KIKA 1J78A 2XVQA 1JNBA 2BXGA 4MBEC 2BXMA 1IJGA 2JUHA 4JK4A 4HGMB 5IJEA 2XMOA 2E0XA 1O9XA 4IW2A 1AO6A 5IIUA 1BM0A 2VUFA 4LB2A 4FIPB 2AJEA 4ZBQA 4L9QA 1GNJA 3B9LA 3G9KD 2CKXA 1HK5A 2LXTA 1MUSA 2NQOA 3KJLA 2GUTA 4ZBKA 4LUFA 4N0FD 3W1SA 2V36A 2BXIA 5B5TA 4F5VA 4G04A 4E99A 2DBUA 1TXUA 3PLAA 2EFEA 1HK1A 3LU8A 4K2CA 5IIHA 3A75A 1UORA 3H37A 2OT3A 1E7CA 5HOZA 4G03A 4J2VA 2LOQA 3SIVB 2NNWA 4F5UA 2BXNA 2E0YA 3GQUA 2DBXA 3MHHB 3GA9L 5FUOA 3FNMA 1HK3A 2BXLA 3JQZA 4ZCGA 3BPJA 2DG5A 4W4UB 4TQ1A 2BXCA 5DQFA 1H9ZA 4F5TA 4FJCB 1SB0A 1E7AA 1E7IA 5BPKA 2OZBB 2BXEA 2XVVA 1GNIA 5IFOA 1LNSA 4Z69A 3FWCC 4DM0A 2ROHA 4GDLB 3WHQA 4BKEA 1LOTA 1MIYA 2QHBA 1E7GA 5GHKA 2LQHA 4D7XA 4LUHA 2BX8A 2Z8IA 4C31B 1MUHA 1KDXA 3H3AA 3LU7A 2XW1A 2Z8KA 3MHSB 2QM6A 3SIUB 1KXPD 5ID7A 1MA9A 4GDXA 4L9KA 1HK2A 1KW2A 4I9OA 2XVUA 4WA6B 2I2ZA 5GIOA 2BXDA 3V08A 3NVKA 2EFCA 3V03A 5IJ5A
chains in the Genus database with same CATH topology
4G01A 1VFIA 1BJ5A 3TDLA 1H5WA 2XW0A 3M99C 2XSIA 2BXAA 4BY9C 4OR0A 4ZUXV 3CX9A 4OT2A 3UIVA 1FOUA 4N3ZA 3SQJA 2BXBA 4F5SA 2DYOA 3WHRA 1E7BA 3ICXA 3VQIA 4OTTA 2BXPA 3JRYA 2BXQA 1BKEA 4GG2A 2VUEA 4GDKB 2VDBA 4IW1A 2DYMA 2XVWA 1MIVA 2DBWA 3GQXA 5IIXA 4K71A 1NT2B 2Z8JA 5GINA 3NMUA 4LA0A 4LB9A 5DBYA 1J7EA 2EFHA 4OTUA 1E7EA 4L8UA 5D7GA 4M70B 1HA2A 4Z9OA 3NVIA 4ZC6A 4TQ0A 1MIWA 2BXFA 2BXOA 2QMCA 2BXHA 4NAWB 4PO0A 1VZSA 2EFDA 1HK4A 3A73A 3NVMA 1E78A 1E7FA 1N5UA 3WHSA 3FWBC 4EMXA 5GIPA 2KBZA 2YDFA 4HGKA 2I30A 5ID9A 1TF0A 4N0UD 1E7HA 3LU6A 2BXKA 3B9MA 4FK5B 3V09A 4S1YA 4DHXB 5IJFA 4ZBRA 3KIKA 1J78A 2XVQA 1JNBA 2BXGA 4MBEC 2BXMA 1IJGA 2JUHA 4JK4A 4HGMB 5IJEA 2XMOA 2E0XA 1O9XA 4IW2A 1AO6A 5IIUA 1BM0A 2VUFA 4LB2A 4FIPB 2AJEA 4ZBQA 4L9QA 1GNJA 3B9LA 3G9KD 2CKXA 1HK5A 2NQOA 3KJLA 4ZBKA 4LUFA 4N0FD 3W1SA 2V36A 2BXIA 5B5TA 4F5VA 4G04A 4E99A 2DBUA 1TXUA 3PLAA 2EFEA 1HK1A 3LU8A 4K2CA 5IIHA 3A75A 1UORA 3H37A 2OT3A 1E7CA 5HOZA 4G03A 4J2VA 2LOQA 3SIVB 2NNWA 4F5UA 2BXNA 2E0YA 3GQUA 2DBXA 3MHHB 3GA9L 5FUOA 3FNMA 1HK3A 2BXLA 3JQZA 4ZCGA 2DG5A 4W4UB 4TQ1A 2BXCA 5DQFA 1H9ZA 4F5TA 4FJCB 1E7AA 1E7IA 5BPKA 2OZBB 2BXEA 2XVVA 1GNIA 5IFOA 1LNSA 4Z69A 3FWCC 2ROHA 4GDLB 3WHQA 4BKEA 1LOTA 1MIYA 2QHBA 1E7GA 5GHKA 4LUHA 2BX8A 2Z8IA 4C31B 3H3AA 3LU7A 2XW1A 2Z8KA 3MHSB 2QM6A 3SIUB 1KXPD 5ID7A 1MA9A 4GDXA 4L9KA 1HK2A 1KW2A 4WA6B 2XVUA 5GIOA 2I2ZA 3NVKA 2BXDA 3V08A 2EFCA 3V03A 5IJ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BJ5 A;  3TDL A;  2XW0 A;  2XSI A;  2BXA A;  4OR0 A;  3CX9 A;  4OT2 A;  3UIV A;  3SQJ A;  2BXB A;  4F5S A;  1E7B A;  2BXP A;  3JRY A;  2BXQ A;  1BKE A;  2VUE A;  2VDB A;  4IW1 A;  2XVW A;  5IIX A;  4K71 A;  4LA0 A;  4LB9 A;  5DBY A;  1J7E A;  1E7E A;  4L8U A;  1HA2 A;  2BXF A;  2BXO A;  2BXH A;  4PO0 A;  1HK4 A;  3A73 A;  1E78 A;  1E7F A;  1N5U A;  4EMX A;  2YDF A;  4HGK A;  2I30 A;  5ID9 A;  1TF0 A;  4N0U D;  1E7H A;  3LU6 A;  2BXK A;  3B9M A;  3V09 A;  5IJF A;  4S1Y A;  4ZBR A;  1J78 A;  2XVQ A;  2BXG A;  2BXM A;  4JK4 A;  4HGM B;  5IJE A;  1O9X A;  4IW2 A;  1AO6 A;  5IIU A;  1BM0 A;  2VUF A;  4LB2 A;  4ZBQ A;  4L9Q A;  1GNJ A;  3B9L A;  1HK5 A;  4LUF A;  4N0F D;  2BXI A;  4F5V A;  4G04 A;  4E99 A;  1HK1 A;  3LU8 A;  4K2C A;  5IIH A;  1UOR A;  5HOZ A;  1E7C A;  4G03 A;  4J2V A;  4F5U A;  2BXN A;  5FUO A;  3JQZ A;  1HK3 A;  2BXL A;  2BXC A;  5DQF A;  1H9Z A;  4F5T A;  1E7A A;  1E7I A;  2BXE A;  2XVV A;  1GNI A;  5IFO A;  4Z69 A;  4BKE A;  1LOT A;  1E7G A;  5GHK A;  4LUH A;  2BX8 A;  3LU7 A;  2XW1 A;  1KXP D;  5ID7 A;  1MA9 A;  4L9K A;  1HK2 A;  1KW2 A;  2XVU A;  2I2Z A;  2BXD A;  3V08 A;  3V03 A;  5IJ5 A; 
#chains in the Genus database with same CATH topology
 4G01 A;  1VFI A;  1BJ5 A;  3TDL A;  1H5W A;  2XW0 A;  3M99 C;  2XSI A;  2BXA A;  1MM8 A;  4BY9 C;  4OR0 A;  2KWF A;  4ZUX V;  3CX9 A;  4OT2 A;  3UIV A;  1FOU A;  4N3Z A;  3SQJ A;  2BXB A;  4F5S A;  2DYO A;  2LXS A;  1E7B A;  3WHR A;  3ICX A;  3VQI A;  4OTT A;  2BXP A;  3JRY A;  2BXQ A;  1BKE A;  4GG2 A;  2VUE A;  4GDK B;  2VDB A;  4IW1 A;  2DYM A;  2XVW A;  1MIV A;  2DBW A;  3GQX A;  5IIX A;  4K71 A;  1NT2 B;  2Z8J A;  5GIN A;  3NMU A;  4LA0 A;  4LB9 A;  5DBY A;  1J7E A;  2EFH A;  4OTU A;  1E7E A;  4L8U A;  5D7G A;  4M70 B;  1HA2 A;  2AGH B;  4Z9O A;  3NVI A;  4ZC6 A;  4TQ0 A;  1MIW A;  2BXF A;  2BXO A;  2QMC A;  2BXH A;  4NAW B;  4PO0 A;  1VZS A;  2EFD A;  1HK4 A;  2LQI A;  3A73 A;  3NVM A;  1E78 A;  1E7F A;  1N5U A;  3WHS A;  3FWB C;  3ECP A;  4EMX A;  5GIP A;  2KBZ A;  2YDF A;  4HGK A;  2I30 A;  2K0N A;  5ID9 A;  1TF0 A;  4N0U D;  1E7H A;  3LU6 A;  2BXK A;  3B9M A;  4FK5 B;  3V09 A;  4S1Y A;  4DHX B;  5IJF A;  4ZBR A;  3KIK A;  1J78 A;  2XVQ A;  1JNB A;  2BXG A;  4MBE C;  2BXM A;  1IJG A;  2JUH A;  4JK4 A;  4HGM B;  5IJE A;  2XMO A;  2E0X A;  1O9X A;  4IW2 A;  1AO6 A;  5IIU A;  1BM0 A;  2VUF A;  4LB2 A;  4FIP B;  2AJE A;  4ZBQ A;  4L9Q A;  1GNJ A;  3B9L A;  3G9K D;  2CKX A;  1HK5 A;  2LXT A;  1MUS A;  2NQO A;  3KJL A;  2GUT A;  4ZBK A;  4LUF A;  4N0F D;  3W1S A;  2V36 A;  2BXI A;  5B5T A;  4F5V A;  4G04 A;  4E99 A;  2DBU A;  1TXU A;  3PLA A;  2EFE A;  1HK1 A;  3LU8 A;  4K2C A;  5IIH A;  3A75 A;  1UOR A;  3H37 A;  2OT3 A;  1E7C A;  5HOZ A;  4G03 A;  4J2V A;  2LOQ A;  3SIV B;  2NNW A;  4F5U A;  2BXN A;  2E0Y A;  3GQU A;  2DBX A;  3MHH B;  3GA9 L;  5FUO A;  3FNM A;  1HK3 A;  2BXL A;  3JQZ A;  4ZCG A;  3BPJ A;  2DG5 A;  4W4U B;  4TQ1 A;  2BXC A;  5DQF A;  1H9Z A;  4F5T A;  4FJC B;  1SB0 A;  1E7A A;  1E7I A;  5BPK A;  2OZB B;  2BXE A;  2XVV A;  1GNI A;  5IFO A;  1LNS A;  4Z69 A;  3FWC C;  4DM0 A;  2ROH A;  4GDL B;  3WHQ A;  4BKE A;  1LOT A;  1MIY A;  2QHB A;  1E7G A;  5GHK A;  2LQH A;  4D7X A;  4LUH A;  2BX8 A;  2Z8I A;  4C31 B;  1MUH A;  1KDX A;  3H3A A;  3LU7 A;  2XW1 A;  2Z8K A;  3MHS B;  2QM6 A;  3SIU B;  1KXP D;  5ID7 A;  1MA9 A;  4GDX A;  4L9K A;  1HK2 A;  1KW2 A;  4I9O A;  2XVU A;  4WA6 B;  2I2Z A;  5GIO A;  2BXD A;  3V08 A;  3NVK A;  2EFC A;  3V03 A;  5IJ5 A; 
#chains in the Genus database with same CATH homology
 4G01 A;  1VFI A;  1BJ5 A;  3TDL A;  1H5W A;  2XW0 A;  3M99 C;  2XSI A;  2BXA A;  4BY9 C;  4OR0 A;  4ZUX V;  3CX9 A;  4OT2 A;  3UIV A;  1FOU A;  4N3Z A;  3SQJ A;  2BXB A;  4F5S A;  2DYO A;  3WHR A;  1E7B A;  3ICX A;  3VQI A;  4OTT A;  2BXP A;  3JRY A;  2BXQ A;  1BKE A;  4GG2 A;  2VUE A;  4GDK B;  2VDB A;  4IW1 A;  2DYM A;  2XVW A;  1MIV A;  2DBW A;  3GQX A;  5IIX A;  4K71 A;  1NT2 B;  2Z8J A;  5GIN A;  3NMU A;  4LA0 A;  4LB9 A;  5DBY A;  1J7E A;  2EFH A;  4OTU A;  1E7E A;  4L8U A;  5D7G A;  4M70 B;  1HA2 A;  4Z9O A;  3NVI A;  4ZC6 A;  4TQ0 A;  1MIW A;  2BXF A;  2BXO A;  2QMC A;  2BXH A;  4NAW B;  4PO0 A;  1VZS A;  2EFD A;  1HK4 A;  3A73 A;  3NVM A;  1E78 A;  1E7F A;  1N5U A;  3WHS A;  3FWB C;  4EMX A;  5GIP A;  2KBZ A;  2YDF A;  4HGK A;  2I30 A;  5ID9 A;  1TF0 A;  4N0U D;  1E7H A;  3LU6 A;  2BXK A;  3B9M A;  4FK5 B;  3V09 A;  4S1Y A;  4DHX B;  5IJF A;  4ZBR A;  3KIK A;  1J78 A;  2XVQ A;  1JNB A;  2BXG A;  4MBE C;  2BXM A;  1IJG A;  2JUH A;  4JK4 A;  4HGM B;  5IJE A;  2XMO A;  2E0X A;  1O9X A;  4IW2 A;  1AO6 A;  5IIU A;  1BM0 A;  2VUF A;  4LB2 A;  4FIP B;  2AJE A;  4ZBQ A;  4L9Q A;  1GNJ A;  3B9L A;  3G9K D;  2CKX A;  1HK5 A;  2NQO A;  3KJL A;  4ZBK A;  4LUF A;  4N0F D;  3W1S A;  2V36 A;  2BXI A;  5B5T A;  4F5V A;  4G04 A;  4E99 A;  2DBU A;  1TXU A;  3PLA A;  2EFE A;  1HK1 A;  3LU8 A;  4K2C A;  5IIH A;  3A75 A;  1UOR A;  3H37 A;  2OT3 A;  1E7C A;  5HOZ A;  4G03 A;  4J2V A;  2LOQ A;  3SIV B;  2NNW A;  4F5U A;  2BXN A;  2E0Y A;  3GQU A;  2DBX A;  3MHH B;  3GA9 L;  5FUO A;  3FNM A;  1HK3 A;  2BXL A;  3JQZ A;  4ZCG A;  2DG5 A;  4W4U B;  4TQ1 A;  2BXC A;  5DQF A;  1H9Z A;  4F5T A;  4FJC B;  1E7A A;  1E7I A;  5BPK A;  2OZB B;  2BXE A;  2XVV A;  1GNI A;  5IFO A;  1LNS A;  4Z69 A;  3FWC C;  2ROH A;  4GDL B;  3WHQ A;  4BKE A;  1LOT A;  1MIY A;  2QHB A;  1E7G A;  5GHK A;  4LUH A;  2BX8 A;  2Z8I A;  4C31 B;  3H3A A;  3LU7 A;  2XW1 A;  2Z8K A;  3MHS B;  2QM6 A;  3SIU B;  1KXP D;  5ID7 A;  1MA9 A;  4GDX A;  4L9K A;  1HK2 A;  1KW2 A;  4WA6 B;  2XVU A;  5GIO A;  2I2Z A;  3NVK A;  2BXD A;  3V08 A;  2EFC A;  3V03 A;  5IJ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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