5ID7A

Crystal structure of human serum albumin in complex with phosphorodithioate derivative of myristoyl cyclic phosphatidic acid (cpa)
Total Genus 233
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
233
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Serum albumin
publication title Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic properties.
pubmed doi rcsb
total genus 233
structure length 582
sequence length 582
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5id7A03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5id7A02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5id7A04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5id7A01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5id7A06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5id7A05
3CX9A 2I30A 1BJ5A 2BXOA 1LOTA 4ZBRA 2BXNA 1E7CA 3A73A 1AO6A 5IIXA 5DBYA 3B9LA 5IJEA 3TDLA 2XSIA 5DQFA 4IW2A 1HK1A 5IIUA 2BXHA 2XW1A 3LU7A 2YDFA 5FUOA 4G03A 4LB2A 1HA2A 5HOZA 5GHKA 5ID9A 4G04A 1E78A 4IW1A 1HK5A 4ZBQA 5IFOA 2BX8A 2XVUA 5IJ5A 3V08A 1KXPD 4J2VA 2BXQA 4F5UA 5IIHA 2BXCA 2BXGA 1O9XA 2BXFA 4LB9A 1E7BA 4HGKA 1E7FA 1GNIA 4JK4A 4LA0A 1HK2A 1E7EA 2XVQA 5IJFA 4BKEA 2BXBA 4S1YA 4LUHA 4K71A 2VUEA 4OR0A 2BXPA 4L8UA 2VDBA 1J7EA 3UIVA 4E99A 1E7IA 2BXEA 2BXIA 4OT2A 4F5VA 2BXMA 2BXDA 1H9ZA 1E7GA 1UORA 2VUFA 4Z69A 4N0UD 1HK3A 3LU6A 3V03A 1TF0A 4K2CA 4L9QA 4L9KA 3V09A 3LU8A 2BXAA 2XVVA 1BM0A 4LUFA 3B9MA 4F5SA 2I2ZA 4N0FD 2XW0A 1E7HA 2BXLA 4HGMB 4PO0A 1J78A 3JRYA 3SQJA 1BKEA 3JQZA 1E7AA 4EMXA 1N5UA 2BXKA 1HK4A 4F5TA 1MA9A 5ID7A 1KW2A 2XVWA 1GNJA
chains in the Genus database with same CATH superfamily
2QM6A 4GG2A 3CX9A 3ICXA 2QMCA 2I30A 1BJ5A 2BXOA 4W4UB 1VZSA 1LOTA 1LNSA 5D7GA 4G01A 2DYOA 1MUSA 4I9OA 4ZBRA 4GDKB 2BXNA 1E7CA 1NT2B 3A73A 4FIPB 1AO6A 5IIXA 2LQHA 5DBYA 5GINA 1MUHA 3B9LA 4N3ZA 3M99C 5IJEA 3TDLA 2XSIA 2LOQA 3MHHB 2KWFA 2EFDA 5DQFA 2DG5A 4IW2A 4ZC6A 3SIVB 1HK1A 5IIUA 2BXHA 2XW1A 2OZBB 2Z8JA 3LU7A 2YDFA 3MHSB 5FUOA 3BPJA 4G03A 4LB2A 2NQOA 1HA2A 2V36A 4WA6B 5HOZA 5GHKA 2EFCA 2Z8IA 5ID9A 2EFEA 4G04A 1E78A 4IW1A 4GDXA 1HK5A 1SB0A 4ZBQA 5IFOA 3SIUB 2BX8A 3GQUA 2EFHA 2XVUA 4MBEC 5IJ5A 2XVWA 1JNBA 1H5WA 3V08A 3PLAA 1KXPD 4J2VA 2BXQA 3W1SA 3FNMA 4F5UA 1IJGA 5IIHA 4DHXB 2KBZA 2LXSA 2BXCA 2BXGA 1O9XA 2BXFA 2E0XA 5GIOA 1TXUA 4FK5B 2K0NA 4LB9A 1E7BA 1E7FA 1GNIA 4HGKA 4JK4A 4LA0A 2GUTA 1HK2A 2DBUA 4M70B 1E7EA 4DM0A 2CKXA 2XVQA 1MM8A 5IJFA 4BKEA 2Z8KA 2BXBA 2LXTA 4S1YA 4LUHA 4K71A 2VUEA 4OR0A 1MIVA 2BXPA 3NVMA 4L8UA 2VDBA 1J7EA 3UIVA 4D7XA 1E7IA 4E99A 3A75A 4Z9OA 2BXEA 2BXIA 3VQIA 4OT2A 4F5VA 3ECPA 2BXMA 2BXDA 5BPKA 1H9ZA 1E7GA 3FWCC 1MIYA 1FOUA 3H3AA 1UORA 3WHSA 2NNWA 2VUFA 4Z69A 4N0UD 2DBWA 4ZUXV 2E0YA 1HK3A 3LU6A 3WHRA 2XMOA 3V03A 2LQIA 1TF0A 4K2CA 4ZBKA 4L9QA 3NVIA 4L9KA 3WHQA 4C31B 1VFIA 3V09A 3LU8A 2BXAA 2XVVA 2JUHA 3H37A 4ZCGA 1BM0A 4NAWB 2OT3A 4LUFA 3B9MA 4F5SA 4TQ0A 2DYMA 4OTUA 5GIPA 2I2ZA 4N0FD 2XW0A 1E7HA 2AGHB 2BXLA 4HGMB 4PO0A 5B5TA 1J78A 3G9KD 1MIWA 4GDLB 3KIKA 3NMUA 3JRYA 3SQJA 1BKEA 3JQZA 4TQ1A 2AJEA 1E7AA 4EMXA 1N5UA 2BXKA 3GA9L 4BY9C 3NVKA 4FJCB 2QHBA 1HK4A 3FWBC 1MA9A 4OTTA 3GQXA 4F5TA 5ID7A 1KW2A 1KDXA 2ROHA 2DBXA 1GNJA 3KJLA
chains in the Genus database with same CATH topology
2QM6A 4GG2A 3CX9A 3ICXA 2QMCA 2I30A 1BJ5A 2BXOA 4W4UB 1VZSA 1LOTA 1LNSA 5D7GA 4G01A 2DYOA 4ZBRA 4GDKB 2BXNA 1E7CA 1NT2B 3A73A 4FIPB 1AO6A 5IIXA 5DBYA 5GINA 3B9LA 4N3ZA 3M99C 5IJEA 3TDLA 2XSIA 2LOQA 3MHHB 5DQFA 2EFDA 2DG5A 4IW2A 4ZC6A 3SIVB 1HK1A 5IIUA 2BXHA 2XW1A 2OZBB 2Z8JA 3LU7A 2YDFA 3MHSB 5FUOA 4G03A 4LB2A 2NQOA 1HA2A 2V36A 4WA6B 5HOZA 5GHKA 2EFCA 2Z8IA 5ID9A 2EFEA 4G04A 1E78A 4IW1A 4GDXA 1HK5A 4ZBQA 5IFOA 3SIUB 2BX8A 3GQUA 2EFHA 2XVUA 4MBEC 5IJ5A 2XVWA 1JNBA 1H5WA 3V08A 3PLAA 1KXPD 4J2VA 2BXQA 3W1SA 3FNMA 4F5UA 1IJGA 5IIHA 4DHXB 2KBZA 2BXCA 2BXGA 1O9XA 2BXFA 2E0XA 5GIOA 1TXUA 4FK5B 4LB9A 1E7BA 1E7FA 1GNIA 4HGKA 4JK4A 4LA0A 4M70B 1HK2A 2DBUA 1E7EA 2CKXA 2XVQA 5IJFA 4BKEA 2Z8KA 2BXBA 4S1YA 4LUHA 4K71A 2VUEA 4OR0A 1MIVA 2BXPA 3NVMA 4L8UA 2VDBA 1J7EA 3UIVA 4E99A 1E7IA 3A75A 4Z9OA 2BXEA 2BXIA 3VQIA 4OT2A 4F5VA 2BXMA 2BXDA 5BPKA 1H9ZA 1E7GA 3FWCC 1MIYA 1FOUA 3H3AA 1UORA 3WHSA 2NNWA 2VUFA 4Z69A 4N0UD 2DBWA 4ZUXV 2E0YA 1HK3A 3LU6A 3WHRA 2XMOA 3V03A 4ZBKA 1TF0A 4K2CA 4L9QA 3NVIA 4L9KA 3WHQA 4C31B 1VFIA 3V09A 3LU8A 2BXAA 2XVVA 2JUHA 3H37A 4ZCGA 1BM0A 4NAWB 2OT3A 4LUFA 3B9MA 4F5SA 4TQ0A 2DYMA 4OTUA 5GIPA 2I2ZA 4N0FD 2XW0A 1E7HA 2BXLA 4HGMB 4PO0A 5B5TA 1J78A 3G9KD 1MIWA 4GDLB 3KIKA 3NMUA 3JRYA 3SQJA 1BKEA 3JQZA 4TQ1A 2AJEA 1E7AA 4EMXA 1N5UA 2BXKA 3GA9L 4BY9C 3NVKA 4FJCB 2QHBA 1HK4A 3FWBC 1MA9A 4OTTA 3GQXA 4F5TA 5ID7A 1KW2A 2ROHA 2DBXA 1GNJA 3KJLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CX9 A;  2I30 A;  1BJ5 A;  2BXO A;  1LOT A;  4ZBR A;  2BXN A;  1E7C A;  3A73 A;  1AO6 A;  5IIX A;  5DBY A;  3B9L A;  5IJE A;  3TDL A;  2XSI A;  5DQF A;  4IW2 A;  1HK1 A;  5IIU A;  2BXH A;  2XW1 A;  3LU7 A;  2YDF A;  5FUO A;  4G03 A;  4LB2 A;  1HA2 A;  5HOZ A;  5GHK A;  5ID9 A;  4G04 A;  1E78 A;  4IW1 A;  1HK5 A;  4ZBQ A;  5IFO A;  2BX8 A;  2XVU A;  5IJ5 A;  3V08 A;  1KXP D;  4J2V A;  2BXQ A;  4F5U A;  5IIH A;  2BXC A;  2BXG A;  1O9X A;  2BXF A;  4LB9 A;  1E7B A;  4HGK A;  1E7F A;  1GNI A;  4JK4 A;  4LA0 A;  1HK2 A;  1E7E A;  2XVQ A;  5IJF A;  4BKE A;  2BXB A;  4S1Y A;  4LUH A;  4K71 A;  2VUE A;  4OR0 A;  2BXP A;  4L8U A;  2VDB A;  1J7E A;  3UIV A;  4E99 A;  1E7I A;  2BXE A;  2BXI A;  4OT2 A;  4F5V A;  2BXM A;  2BXD A;  1H9Z A;  1E7G A;  1UOR A;  2VUF A;  4Z69 A;  4N0U D;  1HK3 A;  3LU6 A;  3V03 A;  1TF0 A;  4K2C A;  4L9Q A;  4L9K A;  3V09 A;  3LU8 A;  2BXA A;  2XVV A;  1BM0 A;  4LUF A;  3B9M A;  4F5S A;  2I2Z A;  4N0F D;  2XW0 A;  1E7H A;  2BXL A;  4HGM B;  4PO0 A;  1J78 A;  3JRY A;  3SQJ A;  1BKE A;  3JQZ A;  1E7A A;  4EMX A;  1N5U A;  2BXK A;  1HK4 A;  4F5T A;  1MA9 A;  5ID7 A;  1KW2 A;  2XVW A;  1GNJ A; 
#chains in the Genus database with same CATH topology
 2QM6 A;  4GG2 A;  3CX9 A;  3ICX A;  2QMC A;  2I30 A;  1BJ5 A;  2BXO A;  4W4U B;  1VZS A;  1LOT A;  1LNS A;  5D7G A;  4G01 A;  2DYO A;  1MUS A;  4I9O A;  4ZBR A;  4GDK B;  2BXN A;  1E7C A;  1NT2 B;  3A73 A;  4FIP B;  1AO6 A;  5IIX A;  2LQH A;  5DBY A;  5GIN A;  1MUH A;  3B9L A;  4N3Z A;  3M99 C;  5IJE A;  3TDL A;  2XSI A;  2LOQ A;  3MHH B;  2KWF A;  2EFD A;  5DQF A;  2DG5 A;  4IW2 A;  4ZC6 A;  3SIV B;  1HK1 A;  5IIU A;  2BXH A;  2XW1 A;  2OZB B;  2Z8J A;  3LU7 A;  2YDF A;  3MHS B;  5FUO A;  3BPJ A;  4G03 A;  4LB2 A;  2NQO A;  1HA2 A;  2V36 A;  4WA6 B;  5HOZ A;  5GHK A;  2EFC A;  2Z8I A;  5ID9 A;  2EFE A;  4G04 A;  1E78 A;  4IW1 A;  4GDX A;  1HK5 A;  1SB0 A;  4ZBQ A;  5IFO A;  3SIU B;  2BX8 A;  3GQU A;  2EFH A;  2XVU A;  4MBE C;  5IJ5 A;  2XVW A;  1JNB A;  1H5W A;  3V08 A;  3PLA A;  1KXP D;  4J2V A;  2BXQ A;  3W1S A;  3FNM A;  4F5U A;  1IJG A;  5IIH A;  4DHX B;  2KBZ A;  2LXS A;  2BXC A;  2BXG A;  1O9X A;  2BXF A;  2E0X A;  5GIO A;  1TXU A;  4FK5 B;  2K0N A;  4LB9 A;  1E7B A;  1E7F A;  1GNI A;  4HGK A;  4JK4 A;  4LA0 A;  2GUT A;  1HK2 A;  2DBU A;  4M70 B;  1E7E A;  4DM0 A;  2CKX A;  2XVQ A;  1MM8 A;  5IJF A;  4BKE A;  2Z8K A;  2BXB A;  2LXT A;  4S1Y A;  4LUH A;  4K71 A;  2VUE A;  4OR0 A;  1MIV A;  2BXP A;  3NVM A;  4L8U A;  2VDB A;  1J7E A;  3UIV A;  4D7X A;  1E7I A;  4E99 A;  3A75 A;  4Z9O A;  2BXE A;  2BXI A;  3VQI A;  4OT2 A;  4F5V A;  3ECP A;  2BXM A;  2BXD A;  5BPK A;  1H9Z A;  1E7G A;  3FWC C;  1MIY A;  1FOU A;  3H3A A;  1UOR A;  3WHS A;  2NNW A;  2VUF A;  4Z69 A;  4N0U D;  2DBW A;  4ZUX V;  2E0Y A;  1HK3 A;  3LU6 A;  3WHR A;  2XMO A;  3V03 A;  2LQI A;  1TF0 A;  4K2C A;  4ZBK A;  4L9Q A;  3NVI A;  4L9K A;  3WHQ A;  4C31 B;  1VFI A;  3V09 A;  3LU8 A;  2BXA A;  2XVV A;  2JUH A;  3H37 A;  4ZCG A;  1BM0 A;  4NAW B;  2OT3 A;  4LUF A;  3B9M A;  4F5S A;  4TQ0 A;  2DYM A;  4OTU A;  5GIP A;  2I2Z A;  4N0F D;  2XW0 A;  1E7H A;  2AGH B;  2BXL A;  4HGM B;  4PO0 A;  5B5T A;  1J78 A;  3G9K D;  1MIW A;  4GDL B;  3KIK A;  3NMU A;  3JRY A;  3SQJ A;  1BKE A;  3JQZ A;  4TQ1 A;  2AJE A;  1E7A A;  4EMX A;  1N5U A;  2BXK A;  3GA9 L;  4BY9 C;  3NVK A;  4FJC B;  2QHB A;  1HK4 A;  3FWB C;  1MA9 A;  4OTT A;  3GQX A;  4F5T A;  5ID7 A;  1KW2 A;  1KDX A;  2ROH A;  2DBX A;  1GNJ A;  3KJL A; 
#chains in the Genus database with same CATH homology
 2QM6 A;  4GG2 A;  3CX9 A;  3ICX A;  2QMC A;  2I30 A;  1BJ5 A;  2BXO A;  4W4U B;  1VZS A;  1LOT A;  1LNS A;  5D7G A;  4G01 A;  2DYO A;  4ZBR A;  4GDK B;  2BXN A;  1E7C A;  1NT2 B;  3A73 A;  4FIP B;  1AO6 A;  5IIX A;  5DBY A;  5GIN A;  3B9L A;  4N3Z A;  3M99 C;  5IJE A;  3TDL A;  2XSI A;  2LOQ A;  3MHH B;  5DQF A;  2EFD A;  2DG5 A;  4IW2 A;  4ZC6 A;  3SIV B;  1HK1 A;  5IIU A;  2BXH A;  2XW1 A;  2OZB B;  2Z8J A;  3LU7 A;  2YDF A;  3MHS B;  5FUO A;  4G03 A;  4LB2 A;  2NQO A;  1HA2 A;  2V36 A;  4WA6 B;  5HOZ A;  5GHK A;  2EFC A;  2Z8I A;  5ID9 A;  2EFE A;  4G04 A;  1E78 A;  4IW1 A;  4GDX A;  1HK5 A;  4ZBQ A;  5IFO A;  3SIU B;  2BX8 A;  3GQU A;  2EFH A;  2XVU A;  4MBE C;  5IJ5 A;  2XVW A;  1JNB A;  1H5W A;  3V08 A;  3PLA A;  1KXP D;  4J2V A;  2BXQ A;  3W1S A;  3FNM A;  4F5U A;  1IJG A;  5IIH A;  4DHX B;  2KBZ A;  2BXC A;  2BXG A;  1O9X A;  2BXF A;  2E0X A;  5GIO A;  1TXU A;  4FK5 B;  4LB9 A;  1E7B A;  1E7F A;  1GNI A;  4HGK A;  4JK4 A;  4LA0 A;  4M70 B;  1HK2 A;  2DBU A;  1E7E A;  2CKX A;  2XVQ A;  5IJF A;  4BKE A;  2Z8K A;  2BXB A;  4S1Y A;  4LUH A;  4K71 A;  2VUE A;  4OR0 A;  1MIV A;  2BXP A;  3NVM A;  4L8U A;  2VDB A;  1J7E A;  3UIV A;  4E99 A;  1E7I A;  3A75 A;  4Z9O A;  2BXE A;  2BXI A;  3VQI A;  4OT2 A;  4F5V A;  2BXM A;  2BXD A;  5BPK A;  1H9Z A;  1E7G A;  3FWC C;  1MIY A;  1FOU A;  3H3A A;  1UOR A;  3WHS A;  2NNW A;  2VUF A;  4Z69 A;  4N0U D;  2DBW A;  4ZUX V;  2E0Y A;  1HK3 A;  3LU6 A;  3WHR A;  2XMO A;  3V03 A;  4ZBK A;  1TF0 A;  4K2C A;  4L9Q A;  3NVI A;  4L9K A;  3WHQ A;  4C31 B;  1VFI A;  3V09 A;  3LU8 A;  2BXA A;  2XVV A;  2JUH A;  3H37 A;  4ZCG A;  1BM0 A;  4NAW B;  2OT3 A;  4LUF A;  3B9M A;  4F5S A;  4TQ0 A;  2DYM A;  4OTU A;  5GIP A;  2I2Z A;  4N0F D;  2XW0 A;  1E7H A;  2BXL A;  4HGM B;  4PO0 A;  5B5T A;  1J78 A;  3G9K D;  1MIW A;  4GDL B;  3KIK A;  3NMU A;  3JRY A;  3SQJ A;  1BKE A;  3JQZ A;  4TQ1 A;  2AJE A;  1E7A A;  4EMX A;  1N5U A;  2BXK A;  3GA9 L;  4BY9 C;  3NVK A;  4FJC B;  2QHB A;  1HK4 A;  3FWB C;  1MA9 A;  4OTT A;  3GQX A;  4F5T A;  5ID7 A;  1KW2 A;  2ROH A;  2DBX A;  1GNJ A;  3KJL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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