5IIXA

Crystal structure of equine serum albumin in the presence of 15 mm zinc at ph 6.5
Total Genus 228
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
228
sequence length
581
structure length
577
Chain Sequence
HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Serum albumin
publication title Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
pubmed doi rcsb
total genus 228
structure length 577
sequence length 581
ec nomenclature
pdb deposition date 2016-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5iixA05
2BX8A 4LUFA 3A73A 1E7CA 1HA2A 4PO0A 4OT2A 1HK4A 4F5VA 1E7HA 1HK1A 1E7GA 1E7EA 2BXLA 2BXAA 2BXIA 5IJFA 4JK4A 2BXQA 4ZBQA 4L9QA 3CX9A 4HGKA 4ZBRA 2BXBA 2XVVA 4OR0A 2BXCA 2I2ZA 2YDFA 5IJ5A 1HK5A 2BXEA 1BM0A 2VUEA 3JRYA 2BXNA 4G03A 5ID9A 2BXKA 5DBYA 1LOTA 2XW0A 1KXPD 1N5UA 2XVUA 1UORA 4LUHA 4IW1A 5IIXA 2BXOA 4N0UD 1HK3A 2VDBA 3V03A 5IFOA 4E99A 4Z69A 1KW2A 4L8UA 2I30A 1GNJA 5GHKA 5IIHA 4N0FD 5ID7A 5IJEA 4LB2A 1E7AA 1H9ZA 1BJ5A 1E7IA 1E78A 2BXPA 5FUOA 1E7FA 5DQFA 1O9XA 1J7EA 2XW1A 1MA9A 4F5TA 1E7BA 4LB9A 3V08A 4F5SA 1J78A 3LU7A 4K2CA 1TF0A 4EMXA 1GNIA 1AO6A 3TDLA 3UIVA 4IW2A 3LU6A 3LU8A 4L9KA 4S1YA 2BXGA 4BKEA 4J2VA 2VUFA 2XVQA 3V09A 2BXMA 3B9MA 4K71A 2BXDA 1HK2A 3B9LA 3JQZA 2XSIA 4HGMB 2BXFA 5IIUA 4F5UA 3SQJA 2BXHA 2XVWA 4G04A 4LA0A 5HOZA 1BKEA
chains in the Genus database with same CATH superfamily
2BX8A 4LUFA 5B5TA 3A73A 1E7CA 1MIWA 1HA2A 4PO0A 4WA6B 4DM0A 4OT2A 1HK4A 4GG2A 2NNWA 1E7HA 4F5VA 1HK1A 1E7GA 4GDKB 3SIUB 3ECPA 3NVKA 1E7EA 2BXLA 2E0YA 4ZUXV 3BPJA 2BXAA 2BXIA 4FK5B 5IJFA 4JK4A 4TQ0A 1MUSA 2BXQA 4ZBQA 3GA9L 5D7GA 4L9QA 3CX9A 3PLAA 3FWBC 4HGKA 3GQUA 3MHHB 4ZBRA 2BXBA 2V36A 2XVVA 4OR0A 4N3ZA 3KIKA 3ICXA 2BXCA 3VQIA 2DG5A 2I2ZA 2YDFA 5IJ5A 3WHSA 1TXUA 1HK5A 2BXEA 2DBUA 1BM0A 2VUEA 3JRYA 2AGHB 4ZC6A 2BXNA 4G03A 5ID9A 2BXKA 3M99C 5GIOA 5DBYA 1LOTA 3H3AA 2XW0A 1KXPD 1N5UA 4OTTA 2NQOA 1UORA 2DBWA 2XVUA 4IW1A 2BXOA 4LUHA 1HK3A 4N0UD 5IIXA 1MM8A 3A75A 2Z8IA 2VDBA 3V03A 3W1SA 5IFOA 4E99A 4FJCB 4Z69A 1KW2A 4L8UA 2I30A 1GNJA 5GHKA 2QM6A 5IIHA 2K0NA 4D7XA 4BY9C 4N0FD 1MIYA 5ID7A 4NAWB 3WHRA 5IJEA 2GUTA 3SIVB 4LB2A 1E7AA 3NVIA 2LXTA 2OZBB 2OT3A 2Z8JA 1H9ZA 1BJ5A 4C31B 1E7IA 2CKXA 3KJLA 1E78A 2BXPA 5FUOA 2KWFA 4TQ1A 2EFCA 1E7FA 5DQFA 4MBEC 2LOQA 2Z8KA 2JUHA 1O9XA 3MHSB 1J7EA 2XW1A 1MA9A 3H37A 1E7BA 4F5TA 1MUHA 4DHXB 4GDXA 4LB9A 4ZCGA 1H5WA 3FWCC 2EFDA 3V08A 4F5SA 2DYOA 5GINA 1VFIA 1MIVA 4W4UB 1J78A 3LU7A 4K2CA 1TF0A 4EMXA 1GNIA 2EFEA 4GDLB 1AO6A 2E0XA 3TDLA 1JNBA 3UIVA 2KBZA 3LU6A 4IW2A 3LU8A 3WHQA 4ZBKA 2QHBA 2QMCA 2AJEA 4L9KA 5GIPA 4S1YA 2BXGA 1FOUA 4BKEA 3G9KD 1LNSA 2VUFA 4J2VA 2XVQA 1SB0A 2DYMA 2BXMA 3B9MA 3V09A 4K71A 3NMUA 1IJGA 1VZSA 1NT2B 2BXDA 2EFHA 1HK2A 2XMOA 5BPKA 3B9LA 3FNMA 3JQZA 3GQXA 2XSIA 4G01A 4OTUA 4HGMB 4I9OA 2ROHA 2BXFA 2LQIA 4F5UA 5IIUA 2DBXA 3SQJA 2BXHA 4Z9OA 3NVMA 4M70B 2XVWA 2LQHA 2LXSA 4G04A 4LA0A 1KDXA 5HOZA 1BKEA 4FIPB
chains in the Genus database with same CATH topology
2BX8A 4LUFA 5B5TA 3A73A 1E7CA 1MIWA 1HA2A 4PO0A 4WA6B 4OT2A 1HK4A 4GG2A 2NNWA 1E7HA 4F5VA 1HK1A 1E7GA 4GDKB 3SIUB 3NVKA 1E7EA 2BXLA 2E0YA 4ZUXV 2BXAA 2BXIA 4FK5B 5IJFA 4JK4A 4TQ0A 2BXQA 4ZBQA 3GA9L 5D7GA 4L9QA 3CX9A 3PLAA 3FWBC 4HGKA 3GQUA 3MHHB 4ZBRA 2BXBA 2V36A 2XVVA 4OR0A 4N3ZA 3KIKA 3ICXA 2BXCA 3VQIA 2DG5A 2I2ZA 2YDFA 5IJ5A 3WHSA 1TXUA 1HK5A 2BXEA 2DBUA 1BM0A 2VUEA 3JRYA 4ZC6A 2BXNA 4G03A 5ID9A 2BXKA 3M99C 5GIOA 5DBYA 1LOTA 3H3AA 2XW0A 1KXPD 1N5UA 4OTTA 2NQOA 1UORA 2DBWA 2XVUA 4IW1A 2BXOA 4LUHA 1HK3A 4N0UD 5IIXA 3A75A 2Z8IA 2VDBA 3V03A 3W1SA 5IFOA 4E99A 4FJCB 4Z69A 1KW2A 4L8UA 2I30A 1GNJA 5GHKA 2QM6A 5IIHA 4BY9C 4N0FD 1MIYA 5ID7A 4NAWB 3WHRA 5IJEA 3SIVB 4LB2A 1E7AA 3NVIA 2OZBB 2OT3A 2Z8JA 1H9ZA 1BJ5A 4C31B 1E7IA 2CKXA 3KJLA 1E78A 2BXPA 5FUOA 4TQ1A 2EFCA 1E7FA 5DQFA 4MBEC 2LOQA 2Z8KA 2JUHA 1O9XA 3MHSB 1J7EA 2XW1A 1MA9A 3H37A 1E7BA 4F5TA 4DHXB 4GDXA 4LB9A 4ZCGA 1H5WA 3FWCC 2EFDA 3V08A 4F5SA 2DYOA 5GINA 1VFIA 1MIVA 4W4UB 1J78A 3LU7A 4K2CA 1TF0A 4EMXA 1GNIA 2EFEA 4GDLB 1AO6A 2E0XA 3TDLA 1JNBA 3UIVA 2KBZA 3LU6A 4IW2A 3LU8A 3WHQA 4ZBKA 2QHBA 2QMCA 2AJEA 4L9KA 5GIPA 4S1YA 2BXGA 1FOUA 4BKEA 3G9KD 1LNSA 2VUFA 4J2VA 2XVQA 2DYMA 2BXMA 3B9MA 3V09A 4K71A 3NMUA 1IJGA 1VZSA 1NT2B 2BXDA 2EFHA 1HK2A 2XMOA 5BPKA 3B9LA 3FNMA 3JQZA 3GQXA 2XSIA 4G01A 4OTUA 4HGMB 2ROHA 2BXFA 5IIUA 4F5UA 2DBXA 3SQJA 2BXHA 4Z9OA 3NVMA 4M70B 2XVWA 4G04A 4LA0A 5HOZA 1BKEA 4FIPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BX8 A;  4LUF A;  3A73 A;  1E7C A;  1HA2 A;  4PO0 A;  4OT2 A;  1HK4 A;  4F5V A;  1E7H A;  1HK1 A;  1E7G A;  1E7E A;  2BXL A;  2BXA A;  2BXI A;  5IJF A;  4JK4 A;  2BXQ A;  4ZBQ A;  4L9Q A;  3CX9 A;  4HGK A;  4ZBR A;  2BXB A;  2XVV A;  4OR0 A;  2BXC A;  2I2Z A;  2YDF A;  5IJ5 A;  1HK5 A;  2BXE A;  1BM0 A;  2VUE A;  3JRY A;  2BXN A;  4G03 A;  5ID9 A;  2BXK A;  5DBY A;  1LOT A;  2XW0 A;  1KXP D;  1N5U A;  2XVU A;  1UOR A;  4LUH A;  4IW1 A;  5IIX A;  2BXO A;  4N0U D;  1HK3 A;  2VDB A;  3V03 A;  5IFO A;  4E99 A;  4Z69 A;  1KW2 A;  4L8U A;  2I30 A;  1GNJ A;  5GHK A;  5IIH A;  4N0F D;  5ID7 A;  5IJE A;  4LB2 A;  1E7A A;  1H9Z A;  1BJ5 A;  1E7I A;  1E78 A;  2BXP A;  5FUO A;  1E7F A;  5DQF A;  1O9X A;  1J7E A;  2XW1 A;  1MA9 A;  4F5T A;  1E7B A;  4LB9 A;  3V08 A;  4F5S A;  1J78 A;  3LU7 A;  4K2C A;  1TF0 A;  4EMX A;  1GNI A;  1AO6 A;  3TDL A;  3UIV A;  4IW2 A;  3LU6 A;  3LU8 A;  4L9K A;  4S1Y A;  2BXG A;  4BKE A;  4J2V A;  2VUF A;  2XVQ A;  3V09 A;  2BXM A;  3B9M A;  4K71 A;  2BXD A;  1HK2 A;  3B9L A;  3JQZ A;  2XSI A;  4HGM B;  2BXF A;  5IIU A;  4F5U A;  3SQJ A;  2BXH A;  2XVW A;  4G04 A;  4LA0 A;  5HOZ A;  1BKE A; 
#chains in the Genus database with same CATH topology
 2BX8 A;  4LUF A;  5B5T A;  3A73 A;  1E7C A;  1MIW A;  1HA2 A;  4PO0 A;  4WA6 B;  4DM0 A;  4OT2 A;  1HK4 A;  4GG2 A;  2NNW A;  1E7H A;  4F5V A;  1HK1 A;  1E7G A;  4GDK B;  3SIU B;  3ECP A;  3NVK A;  1E7E A;  2BXL A;  2E0Y A;  4ZUX V;  3BPJ A;  2BXA A;  2BXI A;  4FK5 B;  5IJF A;  4JK4 A;  4TQ0 A;  1MUS A;  2BXQ A;  4ZBQ A;  3GA9 L;  5D7G A;  4L9Q A;  3CX9 A;  3PLA A;  3FWB C;  4HGK A;  3GQU A;  3MHH B;  4ZBR A;  2BXB A;  2V36 A;  2XVV A;  4OR0 A;  4N3Z A;  3KIK A;  3ICX A;  2BXC A;  3VQI A;  2DG5 A;  2I2Z A;  2YDF A;  5IJ5 A;  3WHS A;  1TXU A;  1HK5 A;  2BXE A;  2DBU A;  1BM0 A;  2VUE A;  3JRY A;  2AGH B;  4ZC6 A;  2BXN A;  4G03 A;  5ID9 A;  2BXK A;  3M99 C;  5GIO A;  5DBY A;  1LOT A;  3H3A A;  2XW0 A;  1KXP D;  1N5U A;  4OTT A;  2NQO A;  1UOR A;  2DBW A;  2XVU A;  4IW1 A;  2BXO A;  4LUH A;  1HK3 A;  4N0U D;  5IIX A;  1MM8 A;  3A75 A;  2Z8I A;  2VDB A;  3V03 A;  3W1S A;  5IFO A;  4E99 A;  4FJC B;  4Z69 A;  1KW2 A;  4L8U A;  2I30 A;  1GNJ A;  5GHK A;  2QM6 A;  5IIH A;  2K0N A;  4D7X A;  4BY9 C;  4N0F D;  1MIY A;  5ID7 A;  4NAW B;  3WHR A;  5IJE A;  2GUT A;  3SIV B;  4LB2 A;  1E7A A;  3NVI A;  2LXT A;  2OZB B;  2OT3 A;  2Z8J A;  1H9Z A;  1BJ5 A;  4C31 B;  1E7I A;  2CKX A;  3KJL A;  1E78 A;  2BXP A;  5FUO A;  2KWF A;  4TQ1 A;  2EFC A;  1E7F A;  5DQF A;  4MBE C;  2LOQ A;  2Z8K A;  2JUH A;  1O9X A;  3MHS B;  1J7E A;  2XW1 A;  1MA9 A;  3H37 A;  1E7B A;  4F5T A;  1MUH A;  4DHX B;  4GDX A;  4LB9 A;  4ZCG A;  1H5W A;  3FWC C;  2EFD A;  3V08 A;  4F5S A;  2DYO A;  5GIN A;  1VFI A;  1MIV A;  4W4U B;  1J78 A;  3LU7 A;  4K2C A;  1TF0 A;  4EMX A;  1GNI A;  2EFE A;  4GDL B;  1AO6 A;  2E0X A;  3TDL A;  1JNB A;  3UIV A;  2KBZ A;  3LU6 A;  4IW2 A;  3LU8 A;  3WHQ A;  4ZBK A;  2QHB A;  2QMC A;  2AJE A;  4L9K A;  5GIP A;  4S1Y A;  2BXG A;  1FOU A;  4BKE A;  3G9K D;  1LNS A;  2VUF A;  4J2V A;  2XVQ A;  1SB0 A;  2DYM A;  2BXM A;  3B9M A;  3V09 A;  4K71 A;  3NMU A;  1IJG A;  1VZS A;  1NT2 B;  2BXD A;  2EFH A;  1HK2 A;  2XMO A;  5BPK A;  3B9L A;  3FNM A;  3JQZ A;  3GQX A;  2XSI A;  4G01 A;  4OTU A;  4HGM B;  4I9O A;  2ROH A;  2BXF A;  2LQI A;  4F5U A;  5IIU A;  2DBX A;  3SQJ A;  2BXH A;  4Z9O A;  3NVM A;  4M70 B;  2XVW A;  2LQH A;  2LXS A;  4G04 A;  4LA0 A;  1KDX A;  5HOZ A;  1BKE A;  4FIP B; 
#chains in the Genus database with same CATH homology
 2BX8 A;  4LUF A;  5B5T A;  3A73 A;  1E7C A;  1MIW A;  1HA2 A;  4PO0 A;  4WA6 B;  4OT2 A;  1HK4 A;  4GG2 A;  2NNW A;  1E7H A;  4F5V A;  1HK1 A;  1E7G A;  4GDK B;  3SIU B;  3NVK A;  1E7E A;  2BXL A;  2E0Y A;  4ZUX V;  2BXA A;  2BXI A;  4FK5 B;  5IJF A;  4JK4 A;  4TQ0 A;  2BXQ A;  4ZBQ A;  3GA9 L;  5D7G A;  4L9Q A;  3CX9 A;  3PLA A;  3FWB C;  4HGK A;  3GQU A;  3MHH B;  4ZBR A;  2BXB A;  2V36 A;  2XVV A;  4OR0 A;  4N3Z A;  3KIK A;  3ICX A;  2BXC A;  3VQI A;  2DG5 A;  2I2Z A;  2YDF A;  5IJ5 A;  3WHS A;  1TXU A;  1HK5 A;  2BXE A;  2DBU A;  1BM0 A;  2VUE A;  3JRY A;  4ZC6 A;  2BXN A;  4G03 A;  5ID9 A;  2BXK A;  3M99 C;  5GIO A;  5DBY A;  1LOT A;  3H3A A;  2XW0 A;  1KXP D;  1N5U A;  4OTT A;  2NQO A;  1UOR A;  2DBW A;  2XVU A;  4IW1 A;  2BXO A;  4LUH A;  1HK3 A;  4N0U D;  5IIX A;  3A75 A;  2Z8I A;  2VDB A;  3V03 A;  3W1S A;  5IFO A;  4E99 A;  4FJC B;  4Z69 A;  1KW2 A;  4L8U A;  2I30 A;  1GNJ A;  5GHK A;  2QM6 A;  5IIH A;  4BY9 C;  4N0F D;  1MIY A;  5ID7 A;  4NAW B;  3WHR A;  5IJE A;  3SIV B;  4LB2 A;  1E7A A;  3NVI A;  2OZB B;  2OT3 A;  2Z8J A;  1H9Z A;  1BJ5 A;  4C31 B;  1E7I A;  2CKX A;  3KJL A;  1E78 A;  2BXP A;  5FUO A;  4TQ1 A;  2EFC A;  1E7F A;  5DQF A;  4MBE C;  2LOQ A;  2Z8K A;  2JUH A;  1O9X A;  3MHS B;  1J7E A;  2XW1 A;  1MA9 A;  3H37 A;  1E7B A;  4F5T A;  4DHX B;  4GDX A;  4LB9 A;  4ZCG A;  1H5W A;  3FWC C;  2EFD A;  3V08 A;  4F5S A;  2DYO A;  5GIN A;  1VFI A;  1MIV A;  4W4U B;  1J78 A;  3LU7 A;  4K2C A;  1TF0 A;  4EMX A;  1GNI A;  2EFE A;  4GDL B;  1AO6 A;  2E0X A;  3TDL A;  1JNB A;  3UIV A;  2KBZ A;  3LU6 A;  4IW2 A;  3LU8 A;  3WHQ A;  4ZBK A;  2QHB A;  2QMC A;  2AJE A;  4L9K A;  5GIP A;  4S1Y A;  2BXG A;  1FOU A;  4BKE A;  3G9K D;  1LNS A;  2VUF A;  4J2V A;  2XVQ A;  2DYM A;  2BXM A;  3B9M A;  3V09 A;  4K71 A;  3NMU A;  1IJG A;  1VZS A;  1NT2 B;  2BXD A;  2EFH A;  1HK2 A;  2XMO A;  5BPK A;  3B9L A;  3FNM A;  3JQZ A;  3GQX A;  2XSI A;  4G01 A;  4OTU A;  4HGM B;  2ROH A;  2BXF A;  5IIU A;  4F5U A;  2DBX A;  3SQJ A;  2BXH A;  4Z9O A;  3NVM A;  4M70 B;  2XVW A;  4G04 A;  4LA0 A;  5HOZ A;  1BKE A;  4FIP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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