5IJEA

Crystal structure of equine serum albumin in the presence of 30 mm zinc at ph 7.4
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
581
structure length
581
Chain Sequence
HKSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKLACLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYRTVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
pubmed doi rcsb
molecule tags Transport protein
molecule keywords Serum albumin
total genus 224
structure length 581
sequence length 581
ec nomenclature
pdb deposition date 2016-03-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijeA05
4PO0A 3B9LA 4G04A 4J2VA 1E7CA 4IW2A 1HK5A 4LB2A 4LUFA 3SQJA 2BXOA 4LA0A 1BM0A 1J78A 4OT2A 1N5UA 2I2ZA 2BXQA 2VUFA 4F5VA 1GNIA 1E7BA 4F5TA 4HGKA 2XVUA 5IIHA 4EMXA 4N0FD 1HK3A 2BXHA 2BXGA 5ID9A 3V03A 3V08A 3LU7A 1HK4A 4BKEA 1HK1A 1E78A 3LU6A 4Z69A 4F5UA 5IFOA 1BKEA 2BXPA 1KW2A 2BXIA 2YDFA 1O9XA 4LUHA 3UIVA 5IIUA 5IJEA 4L9QA 2VDBA 2XSIA 1E7IA 2BXDA 3V09A 5ID7A 1E7EA 4ZBRA 1E7HA 5IJFA 2XW1A 2BXBA 2VUEA 5FUOA 2BXKA 2BXCA 5IJ5A 4OR0A 5DBYA 3B9MA 1E7AA 2XVVA 3LU8A 4IW1A 4N0UD 3JRYA 1AO6A 1E7FA 5HOZA 1H9ZA 2XVWA 2XVQA 2BXFA 4HGMB 1HA2A 4ZBQA 4E99A 3TDLA 3A73A 1GNJA 4L8UA 5GHKA 1TF0A 1LOTA 1BJ5A 2XW0A 3CX9A 1J7EA 4LB9A 2BXLA 2BXMA 1E7GA 1MA9A 4K2CA 2BXEA 4JK4A 1KXPD 2BXNA 4S1YA 4F5SA 5IIXA 1HK2A 3JQZA 4K71A 2BXAA 4L9KA 2I30A 2BX8A 4G03A 1UORA 5DQFA
chains in the Genus database with same CATH superfamily
2DBWA 4PO0A 3B9LA 2QM6A 4G04A 4J2VA 1MM8A 1MUSA 4ZCGA 4MBEC 1E7CA 4IW2A 1HK5A 4LB2A 4LUFA 3WHSA 2OT3A 2E0XA 1NT2B 2DYOA 3SQJA 2BXOA 4DM0A 2AJEA 3NVKA 4GG2A 4LA0A 1BM0A 2LXTA 3WHRA 1J78A 1MUHA 4OT2A 3NVIA 3W1SA 1N5UA 2XMOA 2I2ZA 2BXQA 2LXSA 2VUFA 2DG5A 4F5VA 3SIVB 3ICXA 1GNIA 1E7BA 3KIKA 4F5TA 4HGKA 2XVUA 4DHXB 5IIHA 2EFEA 2AGHB 4EMXA 4N0FD 1HK3A 3VQIA 2LQHA 2NNWA 2BXHA 2LOQA 4OTUA 2BXGA 5ID9A 3PLAA 3FWCC 3V03A 2EFCA 3FWBC 2NQOA 3V08A 1H5WA 3LU7A 1HK4A 2EFDA 4BKEA 1HK1A 1E78A 5B5TA 2QHBA 4D7XA 3LU6A 4Z69A 4TQ1A 3GQUA 4F5UA 4I9OA 5IFOA 1TXUA 2KBZA 1BKEA 2BXPA 1KW2A 2BXIA 2YDFA 1O9XA 4LUHA 4OTTA 4FIPB 3UIVA 5IIUA 5IJEA 4NAWB 2EFHA 2VDBA 4L9QA 2XSIA 1E7IA 2BXDA 3V09A 5ID7A 5GIOA 2GUTA 3H3AA 1E7EA 3GQXA 2Z8JA 4ZC6A 4ZBRA 5GIPA 1E7HA 5IJFA 2DYMA 4GDLB 1FOUA 2XW1A 2BXBA 4G01A 1VFIA 2OZBB 2VUEA 5FUOA 2BXKA 4ZBKA 2BXCA 3A75A 1MIYA 3GA9L 2Z8IA 3G9KD 5IJ5A 4OR0A 2QMCA 5DBYA 3B9MA 1E7AA 2XVVA 3LU8A 4FJCB 4IW1A 4N0UD 3JRYA 1AO6A 4TQ0A 1E7FA 5HOZA 1H9ZA 2LQIA 2XVWA 1MIWA 2XVQA 4BY9C 2BXFA 5D7GA 3H37A 4HGMB 3NVMA 2JUHA 1HA2A 4ZBQA 4E99A 4N3ZA 3TDLA 1KDXA 3A73A 3KJLA 4GDXA 1GNJA 4L8UA 1SB0A 5GHKA 2DBUA 3FNMA 1TF0A 2Z8KA 1LOTA 1BJ5A 2XW0A 4FK5B 5GINA 1JNBA 1J7EA 3CX9A 4C31B 3BPJA 2BXLA 2BXMA 1E7GA 4LB9A 4WA6B 2K0NA 2KWFA 1MA9A 3WHQA 4K2CA 4W4UB 2ROHA 3M99C 3MHHB 2CKXA 3NMUA 1LNSA 1VZSA 2BXEA 4JK4A 2DBXA 3SIUB 1MIVA 4GDKB 4Z9OA 1KXPD 2E0YA 2BXNA 3MHSB 4S1YA 4F5SA 5IIXA 1HK2A 3JQZA 5BPKA 4K71A 4M70B 2V36A 3ECPA 2BXAA 4L9KA 2I30A 2BX8A 4G03A 1UORA 4ZUXV 5DQFA 1IJGA
chains in the Genus database with same CATH topology
2DBWA 4PO0A 3B9LA 2QM6A 4G04A 4J2VA 4ZCGA 4MBEC 1E7CA 4IW2A 1HK5A 4LB2A 4LUFA 3WHSA 2OT3A 2E0XA 1NT2B 2DYOA 3SQJA 2BXOA 2AJEA 3NVKA 4GG2A 4LA0A 1BM0A 3WHRA 1J78A 4OT2A 3NVIA 3W1SA 1N5UA 2XMOA 2I2ZA 2BXQA 2VUFA 2DG5A 4F5VA 3SIVB 3ICXA 1GNIA 1E7BA 3KIKA 4F5TA 4HGKA 2XVUA 4DHXB 5IIHA 2EFEA 4EMXA 4N0FD 1HK3A 3VQIA 2NNWA 2BXHA 2LOQA 4OTUA 2BXGA 5ID9A 3PLAA 3FWCC 3V03A 2EFCA 3FWBC 2NQOA 3V08A 1H5WA 3LU7A 1HK4A 2EFDA 4BKEA 1HK1A 1E78A 5B5TA 2QHBA 3LU6A 4Z69A 4TQ1A 3GQUA 4F5UA 5IFOA 1TXUA 2KBZA 1BKEA 2BXPA 1KW2A 2BXIA 2YDFA 1O9XA 4LUHA 4OTTA 4FIPB 3UIVA 5IIUA 5IJEA 4NAWB 2EFHA 2VDBA 4L9QA 2XSIA 1E7IA 2BXDA 3V09A 5ID7A 5GIOA 3H3AA 1E7EA 3GQXA 2Z8JA 4ZC6A 4ZBRA 5GIPA 1E7HA 5IJFA 2DYMA 4GDLB 1FOUA 2XW1A 2BXBA 4G01A 1VFIA 2OZBB 2VUEA 5FUOA 2BXKA 4ZBKA 2BXCA 3A75A 1MIYA 3GA9L 2Z8IA 3G9KD 5IJ5A 4OR0A 2QMCA 5DBYA 3B9MA 1E7AA 2XVVA 3LU8A 4FJCB 4IW1A 4N0UD 3JRYA 1AO6A 4TQ0A 1E7FA 5HOZA 1H9ZA 2XVWA 1MIWA 2XVQA 4BY9C 2BXFA 5D7GA 3H37A 4HGMB 3NVMA 2JUHA 1HA2A 4ZBQA 4E99A 4N3ZA 3TDLA 3A73A 3KJLA 4GDXA 1GNJA 4L8UA 5GHKA 2DBUA 3FNMA 1TF0A 2Z8KA 1LOTA 1BJ5A 2XW0A 4FK5B 5GINA 1JNBA 1J7EA 3CX9A 4C31B 4LB9A 2BXLA 2BXMA 1E7GA 4WA6B 1MA9A 3WHQA 4K2CA 4W4UB 2ROHA 3M99C 3MHHB 2CKXA 3NMUA 1LNSA 1VZSA 2BXEA 4JK4A 2DBXA 3SIUB 1MIVA 4GDKB 4Z9OA 1KXPD 2E0YA 2BXNA 3MHSB 4S1YA 4F5SA 5IIXA 1HK2A 3JQZA 5BPKA 4K71A 4M70B 2V36A 2BXAA 4L9KA 2I30A 2BX8A 4G03A 1UORA 4ZUXV 5DQFA 1IJGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PO0 A;  3B9L A;  4G04 A;  4J2V A;  1E7C A;  4IW2 A;  1HK5 A;  4LB2 A;  4LUF A;  3SQJ A;  2BXO A;  4LA0 A;  1BM0 A;  1J78 A;  4OT2 A;  1N5U A;  2I2Z A;  2BXQ A;  2VUF A;  4F5V A;  1GNI A;  1E7B A;  4F5T A;  4HGK A;  2XVU A;  5IIH A;  4EMX A;  4N0F D;  1HK3 A;  2BXH A;  2BXG A;  5ID9 A;  3V03 A;  3V08 A;  3LU7 A;  1HK4 A;  4BKE A;  1HK1 A;  1E78 A;  3LU6 A;  4Z69 A;  4F5U A;  5IFO A;  1BKE A;  2BXP A;  1KW2 A;  2BXI A;  2YDF A;  1O9X A;  4LUH A;  3UIV A;  5IIU A;  5IJE A;  4L9Q A;  2VDB A;  2XSI A;  1E7I A;  2BXD A;  3V09 A;  5ID7 A;  1E7E A;  4ZBR A;  1E7H A;  5IJF A;  2XW1 A;  2BXB A;  2VUE A;  5FUO A;  2BXK A;  2BXC A;  5IJ5 A;  4OR0 A;  5DBY A;  3B9M A;  1E7A A;  2XVV A;  3LU8 A;  4IW1 A;  4N0U D;  3JRY A;  1AO6 A;  1E7F A;  5HOZ A;  1H9Z A;  2XVW A;  2XVQ A;  2BXF A;  4HGM B;  1HA2 A;  4ZBQ A;  4E99 A;  3TDL A;  3A73 A;  1GNJ A;  4L8U A;  5GHK A;  1TF0 A;  1LOT A;  1BJ5 A;  2XW0 A;  3CX9 A;  1J7E A;  4LB9 A;  2BXL A;  2BXM A;  1E7G A;  1MA9 A;  4K2C A;  2BXE A;  4JK4 A;  1KXP D;  2BXN A;  4S1Y A;  4F5S A;  5IIX A;  1HK2 A;  3JQZ A;  4K71 A;  2BXA A;  4L9K A;  2I30 A;  2BX8 A;  4G03 A;  1UOR A;  5DQF A; 
#chains in the Genus database with same CATH topology
 2DBW A;  4PO0 A;  3B9L A;  2QM6 A;  4G04 A;  4J2V A;  1MM8 A;  1MUS A;  4ZCG A;  4MBE C;  1E7C A;  4IW2 A;  1HK5 A;  4LB2 A;  4LUF A;  3WHS A;  2OT3 A;  2E0X A;  1NT2 B;  2DYO A;  3SQJ A;  2BXO A;  4DM0 A;  2AJE A;  3NVK A;  4GG2 A;  4LA0 A;  1BM0 A;  2LXT A;  3WHR A;  1J78 A;  1MUH A;  4OT2 A;  3NVI A;  3W1S A;  1N5U A;  2XMO A;  2I2Z A;  2BXQ A;  2LXS A;  2VUF A;  2DG5 A;  4F5V A;  3SIV B;  3ICX A;  1GNI A;  1E7B A;  3KIK A;  4F5T A;  4HGK A;  2XVU A;  4DHX B;  5IIH A;  2EFE A;  2AGH B;  4EMX A;  4N0F D;  1HK3 A;  3VQI A;  2LQH A;  2NNW A;  2BXH A;  2LOQ A;  4OTU A;  2BXG A;  5ID9 A;  3PLA A;  3FWC C;  3V03 A;  2EFC A;  3FWB C;  2NQO A;  3V08 A;  1H5W A;  3LU7 A;  1HK4 A;  2EFD A;  4BKE A;  1HK1 A;  1E78 A;  5B5T A;  2QHB A;  4D7X A;  3LU6 A;  4Z69 A;  4TQ1 A;  3GQU A;  4F5U A;  4I9O A;  5IFO A;  1TXU A;  2KBZ A;  1BKE A;  2BXP A;  1KW2 A;  2BXI A;  2YDF A;  1O9X A;  4LUH A;  4OTT A;  4FIP B;  3UIV A;  5IIU A;  5IJE A;  4NAW B;  2EFH A;  2VDB A;  4L9Q A;  2XSI A;  1E7I A;  2BXD A;  3V09 A;  5ID7 A;  5GIO A;  2GUT A;  3H3A A;  1E7E A;  3GQX A;  2Z8J A;  4ZC6 A;  4ZBR A;  5GIP A;  1E7H A;  5IJF A;  2DYM A;  4GDL B;  1FOU A;  2XW1 A;  2BXB A;  4G01 A;  1VFI A;  2OZB B;  2VUE A;  5FUO A;  2BXK A;  4ZBK A;  2BXC A;  3A75 A;  1MIY A;  3GA9 L;  2Z8I A;  3G9K D;  5IJ5 A;  4OR0 A;  2QMC A;  5DBY A;  3B9M A;  1E7A A;  2XVV A;  3LU8 A;  4FJC B;  4IW1 A;  4N0U D;  3JRY A;  1AO6 A;  4TQ0 A;  1E7F A;  5HOZ A;  1H9Z A;  2LQI A;  2XVW A;  1MIW A;  2XVQ A;  4BY9 C;  2BXF A;  5D7G A;  3H37 A;  4HGM B;  3NVM A;  2JUH A;  1HA2 A;  4ZBQ A;  4E99 A;  4N3Z A;  3TDL A;  1KDX A;  3A73 A;  3KJL A;  4GDX A;  1GNJ A;  4L8U A;  1SB0 A;  5GHK A;  2DBU A;  3FNM A;  1TF0 A;  2Z8K A;  1LOT A;  1BJ5 A;  2XW0 A;  4FK5 B;  5GIN A;  1JNB A;  1J7E A;  3CX9 A;  4C31 B;  3BPJ A;  2BXL A;  2BXM A;  1E7G A;  4LB9 A;  4WA6 B;  2K0N A;  2KWF A;  1MA9 A;  3WHQ A;  4K2C A;  4W4U B;  2ROH A;  3M99 C;  3MHH B;  2CKX A;  3NMU A;  1LNS A;  1VZS A;  2BXE A;  4JK4 A;  2DBX A;  3SIU B;  1MIV A;  4GDK B;  4Z9O A;  1KXP D;  2E0Y A;  2BXN A;  3MHS B;  4S1Y A;  4F5S A;  5IIX A;  1HK2 A;  3JQZ A;  5BPK A;  4K71 A;  4M70 B;  2V36 A;  3ECP A;  2BXA A;  4L9K A;  2I30 A;  2BX8 A;  4G03 A;  1UOR A;  4ZUX V;  5DQF A;  1IJG A; 
#chains in the Genus database with same CATH homology
 2DBW A;  4PO0 A;  3B9L A;  2QM6 A;  4G04 A;  4J2V A;  4ZCG A;  4MBE C;  1E7C A;  4IW2 A;  1HK5 A;  4LB2 A;  4LUF A;  3WHS A;  2OT3 A;  2E0X A;  1NT2 B;  2DYO A;  3SQJ A;  2BXO A;  2AJE A;  3NVK A;  4GG2 A;  4LA0 A;  1BM0 A;  3WHR A;  1J78 A;  4OT2 A;  3NVI A;  3W1S A;  1N5U A;  2XMO A;  2I2Z A;  2BXQ A;  2VUF A;  2DG5 A;  4F5V A;  3SIV B;  3ICX A;  1GNI A;  1E7B A;  3KIK A;  4F5T A;  4HGK A;  2XVU A;  4DHX B;  5IIH A;  2EFE A;  4EMX A;  4N0F D;  1HK3 A;  3VQI A;  2NNW A;  2BXH A;  2LOQ A;  4OTU A;  2BXG A;  5ID9 A;  3PLA A;  3FWC C;  3V03 A;  2EFC A;  3FWB C;  2NQO A;  3V08 A;  1H5W A;  3LU7 A;  1HK4 A;  2EFD A;  4BKE A;  1HK1 A;  1E78 A;  5B5T A;  2QHB A;  3LU6 A;  4Z69 A;  4TQ1 A;  3GQU A;  4F5U A;  5IFO A;  1TXU A;  2KBZ A;  1BKE A;  2BXP A;  1KW2 A;  2BXI A;  2YDF A;  1O9X A;  4LUH A;  4OTT A;  4FIP B;  3UIV A;  5IIU A;  5IJE A;  4NAW B;  2EFH A;  2VDB A;  4L9Q A;  2XSI A;  1E7I A;  2BXD A;  3V09 A;  5ID7 A;  5GIO A;  3H3A A;  1E7E A;  3GQX A;  2Z8J A;  4ZC6 A;  4ZBR A;  5GIP A;  1E7H A;  5IJF A;  2DYM A;  4GDL B;  1FOU A;  2XW1 A;  2BXB A;  4G01 A;  1VFI A;  2OZB B;  2VUE A;  5FUO A;  2BXK A;  4ZBK A;  2BXC A;  3A75 A;  1MIY A;  3GA9 L;  2Z8I A;  3G9K D;  5IJ5 A;  4OR0 A;  2QMC A;  5DBY A;  3B9M A;  1E7A A;  2XVV A;  3LU8 A;  4FJC B;  4IW1 A;  4N0U D;  3JRY A;  1AO6 A;  4TQ0 A;  1E7F A;  5HOZ A;  1H9Z A;  2XVW A;  1MIW A;  2XVQ A;  4BY9 C;  2BXF A;  5D7G A;  3H37 A;  4HGM B;  3NVM A;  2JUH A;  1HA2 A;  4ZBQ A;  4E99 A;  4N3Z A;  3TDL A;  3A73 A;  3KJL A;  4GDX A;  1GNJ A;  4L8U A;  5GHK A;  2DBU A;  3FNM A;  1TF0 A;  2Z8K A;  1LOT A;  1BJ5 A;  2XW0 A;  4FK5 B;  5GIN A;  1JNB A;  1J7E A;  3CX9 A;  4C31 B;  4LB9 A;  2BXL A;  2BXM A;  1E7G A;  4WA6 B;  1MA9 A;  3WHQ A;  4K2C A;  4W4U B;  2ROH A;  3M99 C;  3MHH B;  2CKX A;  3NMU A;  1LNS A;  1VZS A;  2BXE A;  4JK4 A;  2DBX A;  3SIU B;  1MIV A;  4GDK B;  4Z9O A;  1KXP D;  2E0Y A;  2BXN A;  3MHS B;  4S1Y A;  4F5S A;  5IIX A;  1HK2 A;  3JQZ A;  5BPK A;  4K71 A;  4M70 B;  2V36 A;  2BXA A;  4L9K A;  2I30 A;  2BX8 A;  4G03 A;  1UOR A;  4ZUX V;  5DQF A;  1IJG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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