5IJFA

Crystal structure of human serum albumin in the presence of 0.5 mm zinc at ph 9.0
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
sequence length
580
structure length
572
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Serum albumin
publication title Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
pubmed doi rcsb
total genus 199
structure length 572
sequence length 580
ec nomenclature
pdb deposition date 2016-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijfA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijfA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijfA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijfA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijfA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5ijfA05
3V08A 3LU8A 2I30A 4IW1A 2BX8A 4F5VA 4F5TA 1TF0A 4F5UA 4L8UA 4K2CA 4JK4A 5IJFA 2XVQA 4G03A 4LUHA 1E7IA 5ID7A 2BXAA 2XVWA 1E7AA 2BXLA 4L9QA 4IW2A 2XW1A 1O9XA 4LB9A 2BXBA 4J2VA 4ZBQA 1HK1A 4E99A 1HK3A 5DBYA 4OT2A 2BXMA 1GNIA 1N5UA 1HK5A 1KW2A 4N0FD 4Z69A 3JQZA 1E7BA 4F5SA 2BXGA 3LU6A 4ZBRA 2BXPA 4G04A 1J7EA 2BXKA 4PO0A 3B9LA 5IJEA 4S1YA 1BKEA 2VUEA 1E78A 1BJ5A 1J78A 1E7HA 1E7GA 1E7FA 1KXPD 3CX9A 3LU7A 4HGKA 2BXEA 5FUOA 5IFOA 2BXCA 2XW0A 4LB2A 4HGMB 4LUFA 1HK4A 1HK2A 2BXFA 5IIUA 1GNJA 1E7EA 4EMXA 4K71A 1BM0A 2BXHA 2XVUA 5GHKA 2VDBA 2VUFA 5ID9A 1E7CA 1UORA 2BXNA 3V09A 2BXIA 2BXDA 3TDLA 1MA9A 5IIXA 2YDFA 1HA2A 1AO6A 2XSIA 1LOTA 3A73A 4LA0A 4L9KA 2BXOA 5HOZA 3SQJA 4OR0A 3B9MA 5IIHA 4N0UD 4BKEA 5IJ5A 2I2ZA 3JRYA 1H9ZA 3V03A 2XVVA 2BXQA 3UIVA 5DQFA
chains in the Genus database with same CATH superfamily
3V08A 3LU8A 4I9OA 2I30A 4IW1A 2BX8A 4TQ0A 4F5VA 2Z8JA 4F5TA 5GIOA 1TF0A 4F5UA 4L8UA 4ZCGA 5GIPA 2QHBA 4K2CA 4JK4A 5IJFA 2XVQA 2AGHB 4G03A 2K0NA 1E7IA 3FNMA 4LUHA 5ID7A 3WHSA 2BXAA 2XVWA 4GG2A 1E7AA 2DBXA 2BXLA 2V36A 2Z8KA 3GQUA 4IW2A 4L9QA 2XW1A 3MHHB 3SIUB 2DYOA 1O9XA 4LB9A 2BXBA 4J2VA 3NVMA 1JNBA 4FIPB 1HK1A 4ZBQA 4E99A 3KJLA 3KIKA 1HK3A 2KBZA 5DBYA 1VZSA 2DG5A 4OT2A 2BXMA 1GNIA 4W4UB 3WHRA 5GINA 1N5UA 1HK5A 1KW2A 4N0FD 4OTTA 4ZBKA 4Z69A 1FOUA 3JQZA 1E7BA 2LQHA 4F5SA 2BXGA 3LU6A 4ZBRA 3VQIA 2BXPA 2EFCA 4G04A 1J7EA 2BXKA 4TQ1A 1MIVA 4GDLB 2DBWA 4PO0A 4ZUXV 2GUTA 3B9LA 4MBEC 5IJEA 5B5TA 1KDXA 4S1YA 3W1SA 3A75A 1BKEA 2VUEA 3FWBC 4FJCB 4M70B 2CKXA 1E78A 1BJ5A 1J78A 3FWCC 1TXUA 4ZC6A 1E7HA 3ICXA 1E7GA 4DHXB 1E7FA 5D7GA 1KXPD 3ECPA 2OZBB 1H5WA 3CX9A 3LU7A 4HGKA 4OTUA 2NNWA 2BXEA 4G01A 4DM0A 3NMUA 2LOQA 5FUOA 4BY9C 5IFOA 2BXCA 2LQIA 2OT3A 2QMCA 2XW0A 4LB2A 3M99C 2JUHA 4HGMB 4LUFA 2EFDA 1HK4A 1HK2A 2BXFA 5IIUA 1GNJA 1E7EA 4EMXA 4NAWB 3NVIA 4K71A 1BM0A 1VFIA 5BPKA 4GDXA 2BXHA 2LXSA 4N3ZA 3SIVB 2DYMA 2XVUA 5GHKA 2VDBA 3G9KD 3WHQA 3PLAA 1NT2B 2VUFA 5ID9A 1E7CA 3GQXA 1UORA 2BXNA 3V09A 2KWFA 4GDKB 2BXIA 2BXDA 3TDLA 1MA9A 5IIXA 2DBUA 2YDFA 2NQOA 3H37A 1HA2A 4FK5B 2LXTA 1AO6A 1IJGA 2XMOA 2XSIA 1SB0A 1LOTA 3A73A 2Z8IA 4LA0A 4L9KA 2BXOA 1LNSA 5HOZA 2ROHA 1MIWA 3SQJA 4OR0A 1MUHA 3B9MA 4C31B 5IIHA 3H3AA 4D7XA 3MHSB 1MM8A 4N0UD 2QM6A 4BKEA 2AJEA 1MUSA 2EFHA 5IJ5A 2I2ZA 4Z9OA 3JRYA 1MIYA 1H9ZA 2E0XA 3GA9L 3V03A 2XVVA 2E0YA 4WA6B 2BXQA 3UIVA 3NVKA 3BPJA 5DQFA 2EFEA
chains in the Genus database with same CATH topology
3V08A 3LU8A 2I30A 4IW1A 2BX8A 4TQ0A 4F5VA 2Z8JA 4F5TA 5GIOA 1TF0A 4F5UA 4L8UA 4ZCGA 5GIPA 2QHBA 4K2CA 4JK4A 5IJFA 2XVQA 4G03A 3FNMA 1E7IA 4LUHA 5ID7A 3WHSA 2BXAA 2XVWA 4GG2A 1E7AA 2DBXA 2BXLA 2V36A 2Z8KA 3GQUA 4IW2A 4L9QA 2XW1A 3MHHB 3SIUB 2DYOA 1O9XA 4LB9A 2BXBA 4J2VA 3NVMA 1JNBA 4FIPB 1HK1A 4ZBQA 4E99A 3KJLA 3KIKA 1HK3A 2KBZA 5DBYA 1VZSA 2DG5A 4OT2A 2BXMA 1GNIA 4W4UB 3WHRA 5GINA 1N5UA 1HK5A 1KW2A 4N0FD 4OTTA 4ZBKA 4Z69A 1FOUA 3JQZA 1E7BA 4F5SA 2BXGA 3LU6A 4ZBRA 3VQIA 2BXPA 2EFCA 4G04A 1J7EA 2BXKA 4TQ1A 1MIVA 4GDLB 2DBWA 4PO0A 4ZUXV 3B9LA 4MBEC 5IJEA 5B5TA 4S1YA 3W1SA 3A75A 1BKEA 2VUEA 3FWBC 4FJCB 4M70B 2CKXA 1E78A 1BJ5A 1J78A 3FWCC 1TXUA 4ZC6A 1E7HA 3ICXA 1E7GA 4DHXB 1E7FA 5D7GA 1KXPD 2OZBB 1H5WA 3CX9A 3LU7A 4HGKA 4OTUA 2NNWA 2BXEA 4G01A 3NMUA 2LOQA 5FUOA 4BY9C 5IFOA 2BXCA 2OT3A 2QMCA 2XW0A 4LB2A 3M99C 2JUHA 4HGMB 4LUFA 2EFDA 1HK4A 1HK2A 2BXFA 5IIUA 1GNJA 1E7EA 4EMXA 4NAWB 3NVIA 4K71A 1BM0A 1VFIA 5BPKA 4GDXA 2BXHA 4N3ZA 3SIVB 2DYMA 2XVUA 5GHKA 2VDBA 3G9KD 3WHQA 3PLAA 1NT2B 2VUFA 5ID9A 1E7CA 3GQXA 1UORA 2BXNA 3V09A 4GDKB 2BXIA 2BXDA 3TDLA 1MA9A 5IIXA 2DBUA 2YDFA 2NQOA 3H37A 1HA2A 4FK5B 1AO6A 1IJGA 2XMOA 2XSIA 1LOTA 3A73A 2Z8IA 4LA0A 4L9KA 2BXOA 1LNSA 5HOZA 2ROHA 1MIWA 3SQJA 4OR0A 3B9MA 4C31B 5IIHA 3H3AA 3MHSB 4N0UD 2QM6A 4BKEA 2AJEA 2EFHA 5IJ5A 2I2ZA 4Z9OA 3JRYA 1MIYA 1H9ZA 2E0XA 3GA9L 3V03A 2XVVA 2E0YA 4WA6B 2BXQA 3UIVA 3NVKA 5DQFA 2EFEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V08 A;  3LU8 A;  2I30 A;  4IW1 A;  2BX8 A;  4F5V A;  4F5T A;  1TF0 A;  4F5U A;  4L8U A;  4K2C A;  4JK4 A;  5IJF A;  2XVQ A;  4G03 A;  4LUH A;  1E7I A;  5ID7 A;  2BXA A;  2XVW A;  1E7A A;  2BXL A;  4L9Q A;  4IW2 A;  2XW1 A;  1O9X A;  4LB9 A;  2BXB A;  4J2V A;  4ZBQ A;  1HK1 A;  4E99 A;  1HK3 A;  5DBY A;  4OT2 A;  2BXM A;  1GNI A;  1N5U A;  1HK5 A;  1KW2 A;  4N0F D;  4Z69 A;  3JQZ A;  1E7B A;  4F5S A;  2BXG A;  3LU6 A;  4ZBR A;  2BXP A;  4G04 A;  1J7E A;  2BXK A;  4PO0 A;  3B9L A;  5IJE A;  4S1Y A;  1BKE A;  2VUE A;  1E78 A;  1BJ5 A;  1J78 A;  1E7H A;  1E7G A;  1E7F A;  1KXP D;  3CX9 A;  3LU7 A;  4HGK A;  2BXE A;  5FUO A;  5IFO A;  2BXC A;  2XW0 A;  4LB2 A;  4HGM B;  4LUF A;  1HK4 A;  1HK2 A;  2BXF A;  5IIU A;  1GNJ A;  1E7E A;  4EMX A;  4K71 A;  1BM0 A;  2BXH A;  2XVU A;  5GHK A;  2VDB A;  2VUF A;  5ID9 A;  1E7C A;  1UOR A;  2BXN A;  3V09 A;  2BXI A;  2BXD A;  3TDL A;  1MA9 A;  5IIX A;  2YDF A;  1HA2 A;  1AO6 A;  2XSI A;  1LOT A;  3A73 A;  4LA0 A;  4L9K A;  2BXO A;  5HOZ A;  3SQJ A;  4OR0 A;  3B9M A;  5IIH A;  4N0U D;  4BKE A;  5IJ5 A;  2I2Z A;  3JRY A;  1H9Z A;  3V03 A;  2XVV A;  2BXQ A;  3UIV A;  5DQF A; 
#chains in the Genus database with same CATH topology
 3V08 A;  3LU8 A;  4I9O A;  2I30 A;  4IW1 A;  2BX8 A;  4TQ0 A;  4F5V A;  2Z8J A;  4F5T A;  5GIO A;  1TF0 A;  4F5U A;  4L8U A;  4ZCG A;  5GIP A;  2QHB A;  4K2C A;  4JK4 A;  5IJF A;  2XVQ A;  2AGH B;  4G03 A;  2K0N A;  1E7I A;  3FNM A;  4LUH A;  5ID7 A;  3WHS A;  2BXA A;  2XVW A;  4GG2 A;  1E7A A;  2DBX A;  2BXL A;  2V36 A;  2Z8K A;  3GQU A;  4IW2 A;  4L9Q A;  2XW1 A;  3MHH B;  3SIU B;  2DYO A;  1O9X A;  4LB9 A;  2BXB A;  4J2V A;  3NVM A;  1JNB A;  4FIP B;  1HK1 A;  4ZBQ A;  4E99 A;  3KJL A;  3KIK A;  1HK3 A;  2KBZ A;  5DBY A;  1VZS A;  2DG5 A;  4OT2 A;  2BXM A;  1GNI A;  4W4U B;  3WHR A;  5GIN A;  1N5U A;  1HK5 A;  1KW2 A;  4N0F D;  4OTT A;  4ZBK A;  4Z69 A;  1FOU A;  3JQZ A;  1E7B A;  2LQH A;  4F5S A;  2BXG A;  3LU6 A;  4ZBR A;  3VQI A;  2BXP A;  2EFC A;  4G04 A;  1J7E A;  2BXK A;  4TQ1 A;  1MIV A;  4GDL B;  2DBW A;  4PO0 A;  4ZUX V;  2GUT A;  3B9L A;  4MBE C;  5IJE A;  5B5T A;  1KDX A;  4S1Y A;  3W1S A;  3A75 A;  1BKE A;  2VUE A;  3FWB C;  4FJC B;  4M70 B;  2CKX A;  1E78 A;  1BJ5 A;  1J78 A;  3FWC C;  1TXU A;  4ZC6 A;  1E7H A;  3ICX A;  1E7G A;  4DHX B;  1E7F A;  5D7G A;  1KXP D;  3ECP A;  2OZB B;  1H5W A;  3CX9 A;  3LU7 A;  4HGK A;  4OTU A;  2NNW A;  2BXE A;  4G01 A;  4DM0 A;  3NMU A;  2LOQ A;  5FUO A;  4BY9 C;  5IFO A;  2BXC A;  2LQI A;  2OT3 A;  2QMC A;  2XW0 A;  4LB2 A;  3M99 C;  2JUH A;  4HGM B;  4LUF A;  2EFD A;  1HK4 A;  1HK2 A;  2BXF A;  5IIU A;  1GNJ A;  1E7E A;  4EMX A;  4NAW B;  3NVI A;  4K71 A;  1BM0 A;  1VFI A;  5BPK A;  4GDX A;  2BXH A;  2LXS A;  4N3Z A;  3SIV B;  2DYM A;  2XVU A;  5GHK A;  2VDB A;  3G9K D;  3WHQ A;  3PLA A;  1NT2 B;  2VUF A;  5ID9 A;  1E7C A;  3GQX A;  1UOR A;  2BXN A;  3V09 A;  2KWF A;  4GDK B;  2BXI A;  2BXD A;  3TDL A;  1MA9 A;  5IIX A;  2DBU A;  2YDF A;  2NQO A;  3H37 A;  1HA2 A;  4FK5 B;  2LXT A;  1AO6 A;  1IJG A;  2XMO A;  2XSI A;  1SB0 A;  1LOT A;  3A73 A;  2Z8I A;  4LA0 A;  4L9K A;  2BXO A;  1LNS A;  5HOZ A;  2ROH A;  1MIW A;  3SQJ A;  4OR0 A;  1MUH A;  3B9M A;  4C31 B;  5IIH A;  3H3A A;  4D7X A;  3MHS B;  1MM8 A;  4N0U D;  2QM6 A;  4BKE A;  2AJE A;  1MUS A;  2EFH A;  5IJ5 A;  2I2Z A;  4Z9O A;  3JRY A;  1MIY A;  1H9Z A;  2E0X A;  3GA9 L;  3V03 A;  2XVV A;  2E0Y A;  4WA6 B;  2BXQ A;  3UIV A;  3NVK A;  3BPJ A;  5DQF A;  2EFE A; 
#chains in the Genus database with same CATH homology
 3V08 A;  3LU8 A;  2I30 A;  4IW1 A;  2BX8 A;  4TQ0 A;  4F5V A;  2Z8J A;  4F5T A;  5GIO A;  1TF0 A;  4F5U A;  4L8U A;  4ZCG A;  5GIP A;  2QHB A;  4K2C A;  4JK4 A;  5IJF A;  2XVQ A;  4G03 A;  3FNM A;  1E7I A;  4LUH A;  5ID7 A;  3WHS A;  2BXA A;  2XVW A;  4GG2 A;  1E7A A;  2DBX A;  2BXL A;  2V36 A;  2Z8K A;  3GQU A;  4IW2 A;  4L9Q A;  2XW1 A;  3MHH B;  3SIU B;  2DYO A;  1O9X A;  4LB9 A;  2BXB A;  4J2V A;  3NVM A;  1JNB A;  4FIP B;  1HK1 A;  4ZBQ A;  4E99 A;  3KJL A;  3KIK A;  1HK3 A;  2KBZ A;  5DBY A;  1VZS A;  2DG5 A;  4OT2 A;  2BXM A;  1GNI A;  4W4U B;  3WHR A;  5GIN A;  1N5U A;  1HK5 A;  1KW2 A;  4N0F D;  4OTT A;  4ZBK A;  4Z69 A;  1FOU A;  3JQZ A;  1E7B A;  4F5S A;  2BXG A;  3LU6 A;  4ZBR A;  3VQI A;  2BXP A;  2EFC A;  4G04 A;  1J7E A;  2BXK A;  4TQ1 A;  1MIV A;  4GDL B;  2DBW A;  4PO0 A;  4ZUX V;  3B9L A;  4MBE C;  5IJE A;  5B5T A;  4S1Y A;  3W1S A;  3A75 A;  1BKE A;  2VUE A;  3FWB C;  4FJC B;  4M70 B;  2CKX A;  1E78 A;  1BJ5 A;  1J78 A;  3FWC C;  1TXU A;  4ZC6 A;  1E7H A;  3ICX A;  1E7G A;  4DHX B;  1E7F A;  5D7G A;  1KXP D;  2OZB B;  1H5W A;  3CX9 A;  3LU7 A;  4HGK A;  4OTU A;  2NNW A;  2BXE A;  4G01 A;  3NMU A;  2LOQ A;  5FUO A;  4BY9 C;  5IFO A;  2BXC A;  2OT3 A;  2QMC A;  2XW0 A;  4LB2 A;  3M99 C;  2JUH A;  4HGM B;  4LUF A;  2EFD A;  1HK4 A;  1HK2 A;  2BXF A;  5IIU A;  1GNJ A;  1E7E A;  4EMX A;  4NAW B;  3NVI A;  4K71 A;  1BM0 A;  1VFI A;  5BPK A;  4GDX A;  2BXH A;  4N3Z A;  3SIV B;  2DYM A;  2XVU A;  5GHK A;  2VDB A;  3G9K D;  3WHQ A;  3PLA A;  1NT2 B;  2VUF A;  5ID9 A;  1E7C A;  3GQX A;  1UOR A;  2BXN A;  3V09 A;  4GDK B;  2BXI A;  2BXD A;  3TDL A;  1MA9 A;  5IIX A;  2DBU A;  2YDF A;  2NQO A;  3H37 A;  1HA2 A;  4FK5 B;  1AO6 A;  1IJG A;  2XMO A;  2XSI A;  1LOT A;  3A73 A;  2Z8I A;  4LA0 A;  4L9K A;  2BXO A;  1LNS A;  5HOZ A;  2ROH A;  1MIW A;  3SQJ A;  4OR0 A;  3B9M A;  4C31 B;  5IIH A;  3H3A A;  3MHS B;  4N0U D;  2QM6 A;  4BKE A;  2AJE A;  2EFH A;  5IJ5 A;  2I2Z A;  4Z9O A;  3JRY A;  1MIY A;  1H9Z A;  2E0X A;  3GA9 L;  3V03 A;  2XVV A;  2E0Y A;  4WA6 B;  2BXQ A;  3UIV A;  3NVK A;  5DQF A;  2EFE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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