1ANJA

Alkaline phosphatase (k328h)
Total Genus 160
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
160
Knots found
sequence length
446
structure length
446
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDHQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Alkaline phosphatase
molecule keywords ALKALINE PHOSPHATASE
publication title Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
pubmed doi rcsb
source organism Escherichia coli
total genus 160
structure length 446
sequence length 446
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1995-09-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1anjA00
1ZEDA 1SHNA 5EGEA 3UO0A 3SZYA 1EQJA 4CYSA 3CMRA 3NKMA 1N2LA 2W5TA 5GOVA 5GRRA 3TG0A 2W5QA 1ED8A 3MK0A 4ZG9A 2VQRA 1URAA 1AJCA 2W5VA 3WAWA 4GTXA 3UN5A 3E2DA 3OT9A 5L0BA 3TX0A 1ELXA 3WAYA 1KH7A 1ALKA 1HDHA 1EW9A 3MK2A 3NKRA 5INHA 4KJGA 1ANJA 4FDJA 1EW8A 1AJBA 1E33P 5LQQA 4MIVA 3WAVA 3UN2A 2W5WA 2IFYA 1AJDA 3BDGA 4LRDA 5EGHA 3BDHA 5DLTA 1ELZA 4KAYA 3Q3QA 5K4PA 5LIAA 4UOOA 1KHKA 2XR9A 4N7TA 3IDDA 1FSUA 4GTWA 4TN0A 5C66A 1AJAA 1Y6VA 4UORA 5DLWA 2GLQA 3NKQA 4NWJA 2W8SA 3T01A 3ED4A 1ED9A 1SHQA 3UN3A 1N2KA 2W5XA 3BDFA 3LXQA 3NKPA 1E2SP 4UPIA 2W8DA 1AUKA 3B5QA 3BDGB 4FDIA 5IJSA 2GSNA 1EI6A 2W5RA 4CXKA 2XRGA 1O99A 2GSOA 1ALJA 2W5SA 4GTZA 1K7HA 2GA3A 1KH4A 4GTYA 4B56A 1KHJA 1EW2A 2IUCA 4LR2A 1KHNA 3WBHA 1KH9A 4KAVA 4LRCA 2X98A 1O98A 4MY4A 4UOPA 5TJ3A 1ANIA 5AJ9A 1HQAA 5L0EA 5LRMA 3KD8A 5DLVA 1E3CP 1B8JA 1E1ZP 3DYCA 4KM4A 2ANHA 3UNYA 4YR1A 4LR9A 5KXAA 4KJDA 2ZKTA 2D1GA 4LRAA 3IGZB 2G9YA 4LRFA 3T02A 1Y7AA 3WAXA 4CXUA 4ZG6A 5LRNA 1ZEFA 4UPLA 1KH5A 3NVLA 4ZG7A 2IUCB 2RH6A 2GSUA 4LR8A 3TWZA 2QZUA 4LR7A 4CXSA 1ELYA 5HRTA 1P49A 3A52A 4MHXA 4UPKA 1ZEBA 4LRBA 3M8YA 3DPCA 3MK1A 4UPHA 1ALIA 1URBA 1EJJA 1HJKA 4CYRA 3T00A 3NKOA 3NKNA 3SZZA 3IGYB 1ALHA 4ZGAA 3M8WA 4NWXA 5IJQA 4LQYA 4QAXA 5L0KA 3M8ZA 1KHLA 3M7VA 4LREA
chains in the Genus database with same CATH superfamily
1ZEDA 1SHNA 5EGEA 3UO0A 3SZYA 1EQJA 4CYSA 3CMRA 3NKMA 1N2LA 2W5TA 5GOVA 5GRRA 3TG0A 2W5QA 1ED8A 3MK0A 4ZG9A 2VQRA 1URAA 1AJCA 2W5VA 3WAWA 4GTXA 3UN5A 3E2DA 3OT9A 5L0BA 3TX0A 1ELXA 3WAYA 1KH7A 1ALKA 1HDHA 1EW9A 3MK2A 3NKRA 5INHA 4KJGA 1ANJA 4FDJA 1EW8A 1AJBA 1E33P 5LQQA 4MIVA 3WAVA 3UN2A 2W5WA 2IFYA 1AJDA 3BDGA 4LRDA 5EGHA 3BDHA 5DLTA 1ELZA 4KAYA 3Q3QA 5K4PA 5LIAA 4UOOA 1KHKA 2XR9A 4N7TA 3IDDA 1FSUA 4GTWA 4TN0A 5C66A 1AJAA 1Y6VA 4UORA 5DLWA 2GLQA 3NKQA 4NWJA 2W8SA 3T01A 3ED4A 1ED9A 1SHQA 3UN3A 1N2KA 2W5XA 3BDFA 3LXQA 3NKPA 1E2SP 4UPIA 2W8DA 1AUKA 3B5QA 3BDGB 4FDIA 5IJSA 2GSNA 1EI6A 2W5RA 4CXKA 2XRGA 1O99A 2GSOA 1ALJA 2W5SA 4GTZA 1K7HA 2GA3A 1KH4A 4GTYA 4B56A 1KHJA 1EW2A 2IUCA 4LR2A 1KHNA 3WBHA 1KH9A 4KAVA 4LRCA 2X98A 1O98A 4MY4A 4UOPA 5TJ3A 1ANIA 5AJ9A 1HQAA 5L0EA 5LRMA 3KD8A 5DLVA 1E3CP 1B8JA 1E1ZP 3DYCA 4KM4A 2ANHA 3UNYA 4YR1A 4LR9A 5KXAA 4KJDA 2ZKTA 2D1GA 4LRAA 3IGZB 2G9YA 4LRFA 3T02A 1Y7AA 3WAXA 4CXUA 4ZG6A 5LRNA 1ZEFA 4UPLA 1KH5A 3NVLA 4ZG7A 2IUCB 2RH6A 2GSUA 4LR8A 3TWZA 2QZUA 4LR7A 4CXSA 1ELYA 5HRTA 1P49A 3A52A 4MHXA 4UPKA 1ZEBA 4LRBA 3M8YA 3DPCA 3MK1A 4UPHA 1ALIA 1URBA 1EJJA 1HJKA 4CYRA 3T00A 3NKOA 3NKNA 3SZZA 3IGYB 1ALHA 4ZGAA 3M8WA 4NWXA 5IJQA 4LQYA 4QAXA 5L0KA 3M8ZA 1KHLA 3M7VA 4LREA
chains in the Genus database with same CATH topology
1ZEDA 1SHNA 5EGEA 3UO0A 3SZYA 1EQJA 4CYSA 3CMRA 3NKMA 1N2LA 2W5TA 5GOVA 5GRRA 3TG0A 2W5QA 1ED8A 3MK0A 4ZG9A 2VQRA 1URAA 1AJCA 2W5VA 3WAWA 4GTXA 3UN5A 3E2DA 3OT9A 5L0BA 3TX0A 1ELXA 3WAYA 1KH7A 1ALKA 1HDHA 1EW9A 3MK2A 3NKRA 5INHA 4KJGA 1ANJA 4FDJA 1EW8A 1AJBA 1E33P 5LQQA 4MIVA 3WAVA 3UN2A 2W5WA 2IFYA 1AJDA 3BDGA 4LRDA 5EGHA 3BDHA 5DLTA 1ELZA 4KAYA 3Q3QA 5K4PA 5LIAA 4UOOA 1KHKA 2XR9A 4N7TA 3IDDA 1FSUA 4GTWA 4TN0A 5C66A 1AJAA 1Y6VA 4UORA 5DLWA 2GLQA 3NKQA 4NWJA 2W8SA 3T01A 3ED4A 1ED9A 1SHQA 3UN3A 1N2KA 2W5XA 3BDFA 3LXQA 3NKPA 1E2SP 4UPIA 2W8DA 1AUKA 3B5QA 3BDGB 4FDIA 5IJSA 2GSNA 1EI6A 2W5RA 4CXKA 2XRGA 1O99A 2GSOA 1ALJA 2W5SA 4GTZA 1K7HA 2GA3A 1KH4A 4GTYA 4B56A 1KHJA 1EW2A 2IUCA 4LR2A 1KHNA 3WBHA 1KH9A 4KAVA 4LRCA 2X98A 1O98A 4MY4A 4UOPA 5TJ3A 1ANIA 5AJ9A 1HQAA 5L0EA 5LRMA 3KD8A 5DLVA 1E3CP 1B8JA 1E1ZP 3DYCA 4KM4A 2ANHA 3UNYA 4YR1A 4LR9A 5KXAA 4KJDA 2ZKTA 2D1GA 4LRAA 3IGZB 2G9YA 4LRFA 3T02A 1Y7AA 3WAXA 4CXUA 4ZG6A 5LRNA 1ZEFA 4UPLA 1KH5A 3NVLA 4ZG7A 2IUCB 2RH6A 2GSUA 4LR8A 3TWZA 2QZUA 4LR7A 4CXSA 1ELYA 5HRTA 1P49A 3A52A 4MHXA 4UPKA 1ZEBA 4LRBA 3M8YA 3DPCA 3MK1A 4UPHA 1ALIA 1URBA 1EJJA 1HJKA 4CYRA 3T00A 3NKOA 3NKNA 3SZZA 3IGYB 1ALHA 4ZGAA 3M8WA 4NWXA 5IJQA 4LQYA 4QAXA 5L0KA 3M8ZA 1KHLA 3M7VA 4LREA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZED A;  1SHN A;  5EGE A;  3UO0 A;  3SZY A;  1EQJ A;  4CYS A;  3CMR A;  3NKM A;  1N2L A;  2W5T A;  5GOV A;  5GRR A;  3TG0 A;  2W5Q A;  1ED8 A;  3MK0 A;  4ZG9 A;  2VQR A;  1URA A;  1AJC A;  2W5V A;  3WAW A;  4GTX A;  3UN5 A;  3E2D A;  3OT9 A;  5L0B A;  3TX0 A;  1ELX A;  3WAY A;  1KH7 A;  1ALK A;  1HDH A;  1EW9 A;  3MK2 A;  3NKR A;  5INH A;  4KJG A;  1ANJ A;  4FDJ A;  1EW8 A;  1AJB A;  1E33 P;  5LQQ A;  4MIV A;  3WAV A;  3UN2 A;  2W5W A;  2IFY A;  1AJD A;  3BDG A;  4LRD A;  5EGH A;  3BDH A;  5DLT A;  1ELZ A;  4KAY A;  3Q3Q A;  5K4P A;  5LIA A;  4UOO A;  1KHK A;  2XR9 A;  4N7T A;  3IDD A;  1FSU A;  4GTW A;  4TN0 A;  5C66 A;  1AJA A;  1Y6V A;  4UOR A;  5DLW A;  2GLQ A;  3NKQ A;  4NWJ A;  2W8S A;  3T01 A;  3ED4 A;  1ED9 A;  1SHQ A;  3UN3 A;  1N2K A;  2W5X A;  3BDF A;  3LXQ A;  3NKP A;  1E2S P;  4UPI A;  2W8D A;  1AUK A;  3B5Q A;  3BDG B;  4FDI A;  5IJS A;  2GSN A;  1EI6 A;  2W5R A;  4CXK A;  2XRG A;  1O99 A;  2GSO A;  1ALJ A;  2W5S A;  4GTZ A;  1K7H A;  2GA3 A;  1KH4 A;  4GTY A;  4B56 A;  1KHJ A;  1EW2 A;  2IUC A;  4LR2 A;  1KHN A;  3WBH A;  1KH9 A;  4KAV A;  4LRC A;  2X98 A;  1O98 A;  4MY4 A;  4UOP A;  5TJ3 A;  1ANI A;  5AJ9 A;  1HQA A;  5L0E A;  5LRM A;  3KD8 A;  5DLV A;  1E3C P;  1B8J A;  1E1Z P;  3DYC A;  4KM4 A;  2ANH A;  3UNY A;  4YR1 A;  4LR9 A;  5KXA A;  4KJD A;  2ZKT A;  2D1G A;  4LRA A;  3IGZ B;  2G9Y A;  4LRF A;  3T02 A;  1Y7A A;  3WAX A;  4CXU A;  4ZG6 A;  5LRN A;  1ZEF A;  4UPL A;  1KH5 A;  3NVL A;  4ZG7 A;  2IUC B;  2RH6 A;  2GSU A;  4LR8 A;  3TWZ A;  2QZU A;  4LR7 A;  4CXS A;  1ELY A;  5HRT A;  1P49 A;  3A52 A;  4MHX A;  4UPK A;  1ZEB A;  4LRB A;  3M8Y A;  3DPC A;  3MK1 A;  4UPH A;  1ALI A;  1URB A;  1EJJ A;  1HJK A;  4CYR A;  3T00 A;  3NKO A;  3NKN A;  3SZZ A;  3IGY B;  1ALH A;  4ZGA A;  3M8W A;  4NWX A;  5IJQ A;  4LQY A;  4QAX A;  5L0K A;  3M8Z A;  1KHL A;  3M7V A;  4LRE A; 
#chains in the Genus database with same CATH topology
 1ZED A;  1SHN A;  5EGE A;  3UO0 A;  3SZY A;  1EQJ A;  4CYS A;  3CMR A;  3NKM A;  1N2L A;  2W5T A;  5GOV A;  5GRR A;  3TG0 A;  2W5Q A;  1ED8 A;  3MK0 A;  4ZG9 A;  2VQR A;  1URA A;  1AJC A;  2W5V A;  3WAW A;  4GTX A;  3UN5 A;  3E2D A;  3OT9 A;  5L0B A;  3TX0 A;  1ELX A;  3WAY A;  1KH7 A;  1ALK A;  1HDH A;  1EW9 A;  3MK2 A;  3NKR A;  5INH A;  4KJG A;  1ANJ A;  4FDJ A;  1EW8 A;  1AJB A;  1E33 P;  5LQQ A;  4MIV A;  3WAV A;  3UN2 A;  2W5W A;  2IFY A;  1AJD A;  3BDG A;  4LRD A;  5EGH A;  3BDH A;  5DLT A;  1ELZ A;  4KAY A;  3Q3Q A;  5K4P A;  5LIA A;  4UOO A;  1KHK A;  2XR9 A;  4N7T A;  3IDD A;  1FSU A;  4GTW A;  4TN0 A;  5C66 A;  1AJA A;  1Y6V A;  4UOR A;  5DLW A;  2GLQ A;  3NKQ A;  4NWJ A;  2W8S A;  3T01 A;  3ED4 A;  1ED9 A;  1SHQ A;  3UN3 A;  1N2K A;  2W5X A;  3BDF A;  3LXQ A;  3NKP A;  1E2S P;  4UPI A;  2W8D A;  1AUK A;  3B5Q A;  3BDG B;  4FDI A;  5IJS A;  2GSN A;  1EI6 A;  2W5R A;  4CXK A;  2XRG A;  1O99 A;  2GSO A;  1ALJ A;  2W5S A;  4GTZ A;  1K7H A;  2GA3 A;  1KH4 A;  4GTY A;  4B56 A;  1KHJ A;  1EW2 A;  2IUC A;  4LR2 A;  1KHN A;  3WBH A;  1KH9 A;  4KAV A;  4LRC A;  2X98 A;  1O98 A;  4MY4 A;  4UOP A;  5TJ3 A;  1ANI A;  5AJ9 A;  1HQA A;  5L0E A;  5LRM A;  3KD8 A;  5DLV A;  1E3C P;  1B8J A;  1E1Z P;  3DYC A;  4KM4 A;  2ANH A;  3UNY A;  4YR1 A;  4LR9 A;  5KXA A;  4KJD A;  2ZKT A;  2D1G A;  4LRA A;  3IGZ B;  2G9Y A;  4LRF A;  3T02 A;  1Y7A A;  3WAX A;  4CXU A;  4ZG6 A;  5LRN A;  1ZEF A;  4UPL A;  1KH5 A;  3NVL A;  4ZG7 A;  2IUC B;  2RH6 A;  2GSU A;  4LR8 A;  3TWZ A;  2QZU A;  4LR7 A;  4CXS A;  1ELY A;  5HRT A;  1P49 A;  3A52 A;  4MHX A;  4UPK A;  1ZEB A;  4LRB A;  3M8Y A;  3DPC A;  3MK1 A;  4UPH A;  1ALI A;  1URB A;  1EJJ A;  1HJK A;  4CYR A;  3T00 A;  3NKO A;  3NKN A;  3SZZ A;  3IGY B;  1ALH A;  4ZGA A;  3M8W A;  4NWX A;  5IJQ A;  4LQY A;  4QAX A;  5L0K A;  3M8Z A;  1KHL A;  3M7V A;  4LRE A; 
#chains in the Genus database with same CATH homology
 1ZED A;  1SHN A;  5EGE A;  3UO0 A;  3SZY A;  1EQJ A;  4CYS A;  3CMR A;  3NKM A;  1N2L A;  2W5T A;  5GOV A;  5GRR A;  3TG0 A;  2W5Q A;  1ED8 A;  3MK0 A;  4ZG9 A;  2VQR A;  1URA A;  1AJC A;  2W5V A;  3WAW A;  4GTX A;  3UN5 A;  3E2D A;  3OT9 A;  5L0B A;  3TX0 A;  1ELX A;  3WAY A;  1KH7 A;  1ALK A;  1HDH A;  1EW9 A;  3MK2 A;  3NKR A;  5INH A;  4KJG A;  1ANJ A;  4FDJ A;  1EW8 A;  1AJB A;  1E33 P;  5LQQ A;  4MIV A;  3WAV A;  3UN2 A;  2W5W A;  2IFY A;  1AJD A;  3BDG A;  4LRD A;  5EGH A;  3BDH A;  5DLT A;  1ELZ A;  4KAY A;  3Q3Q A;  5K4P A;  5LIA A;  4UOO A;  1KHK A;  2XR9 A;  4N7T A;  3IDD A;  1FSU A;  4GTW A;  4TN0 A;  5C66 A;  1AJA A;  1Y6V A;  4UOR A;  5DLW A;  2GLQ A;  3NKQ A;  4NWJ A;  2W8S A;  3T01 A;  3ED4 A;  1ED9 A;  1SHQ A;  3UN3 A;  1N2K A;  2W5X A;  3BDF A;  3LXQ A;  3NKP A;  1E2S P;  4UPI A;  2W8D A;  1AUK A;  3B5Q A;  3BDG B;  4FDI A;  5IJS A;  2GSN A;  1EI6 A;  2W5R A;  4CXK A;  2XRG A;  1O99 A;  2GSO A;  1ALJ A;  2W5S A;  4GTZ A;  1K7H A;  2GA3 A;  1KH4 A;  4GTY A;  4B56 A;  1KHJ A;  1EW2 A;  2IUC A;  4LR2 A;  1KHN A;  3WBH A;  1KH9 A;  4KAV A;  4LRC A;  2X98 A;  1O98 A;  4MY4 A;  4UOP A;  5TJ3 A;  1ANI A;  5AJ9 A;  1HQA A;  5L0E A;  5LRM A;  3KD8 A;  5DLV A;  1E3C P;  1B8J A;  1E1Z P;  3DYC A;  4KM4 A;  2ANH A;  3UNY A;  4YR1 A;  4LR9 A;  5KXA A;  4KJD A;  2ZKT A;  2D1G A;  4LRA A;  3IGZ B;  2G9Y A;  4LRF A;  3T02 A;  1Y7A A;  3WAX A;  4CXU A;  4ZG6 A;  5LRN A;  1ZEF A;  4UPL A;  1KH5 A;  3NVL A;  4ZG7 A;  2IUC B;  2RH6 A;  2GSU A;  4LR8 A;  3TWZ A;  2QZU A;  4LR7 A;  4CXS A;  1ELY A;  5HRT A;  1P49 A;  3A52 A;  4MHX A;  4UPK A;  1ZEB A;  4LRB A;  3M8Y A;  3DPC A;  3MK1 A;  4UPH A;  1ALI A;  1URB A;  1EJJ A;  1HJK A;  4CYR A;  3T00 A;  3NKO A;  3NKN A;  3SZZ A;  3IGY B;  1ALH A;  4ZGA A;  3M8W A;  4NWX A;  5IJQ A;  4LQY A;  4QAX A;  5L0K A;  3M8Z A;  1KHL A;  3M7V A;  4LRE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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