4MIVA

Crystal structure of sulfamidase, crystal form l
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
Knots found
sequence length
484
structure length
483
Chain Sequence
PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNELRSH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords N-sulphoglucosamine sulphohydrolase
publication title Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 169
structure length 483
sequence length 484
chains with identical sequence B, C, D, E, F, G, H
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.10.1.1: N-sulfoglucosamine sulfohydrolase.
pdb deposition date 2013-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
A PF16347 DUF4976 Domain of unknown function (DUF4976)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4mivA01
3NKOA 1URBA 2GSOA 1ALJA 3SZYA 4GTWA 1B8JA 1E3CP 4CYRA 5L0EA 2X98A 1ELZA 1KH9A 1Y6VA 3BDGB 3WAVA 3NKMA 3WAWA 4KJDA 4GTZA 2W5QA 3M7VA 4ZG7A 4KAYA 1N2KA 2XRGA 5EGHA 1ANIA 2ANHA 4CXUA 3T01A 5GRRA 1O99A 1URAA 4LR9A 3DPCA 3UO0A 4LRAA 3MK1A 3E2DA 2GSNA 3B5QA 4MIVA 3TWZA 1KHJA 4UPLA 3CMRA 4N7TA 1EJJA 1KHLA 1AJAA 5INHA 1FSUA 1ZEDA 2W8DA 5TJ3A 4B56A 1E1ZP 2W5TA 3KD8A 3TX0A 1ELYA 2D1GA 5KXAA 3LXQA 1KHKA 4QAXA 3A52A 3NKNA 1ED8A 1SHQA 3SZZA 3WBHA 5L0BA 3WAYA 3BDFA 1ALIA 3BDHA 1N2LA 1ANJA 3UN2A 4NWXA 3MK0A 2GSUA 2IUCB 1EW2A 3M8ZA 2W5VA 1ALHA 1AJBA 1KH5A 4LRCA 4UOOA 3DYCA 4LR8A 5L0KA 3IGZB 1ALKA 5C66A 4LRBA 4FDJA 4UPKA 5AJ9A 4LREA 1ED9A 4KAVA 1EW8A 2QZUA 1ELXA 1HQAA 1O98A 4CYSA 4FDIA 1ZEFA 3T00A 1EW9A 3IDDA 3OT9A 5EGEA 3NKPA 3NKQA 4LR7A 1Y7AA 1K7HA 1EQJA 4UPHA 4CXSA 2ZKTA 1KHNA 3M8WA 3UNYA 4LQYA 3NKRA 5LIAA 5IJQA 4LR2A 1AUKA 3NVLA 2RH6A 4UORA 4UPIA 4GTYA 4ZGAA 4LRFA 5LQQA 2W5RA 1E2SP 3UN3A 1KH4A 1KH7A 4GTXA 1EI6A 2W5WA 3Q3QA 2W8SA 3ED4A 4MY4A 4YR1A 2GA3A 4ZG6A 2IFYA 3BDGA 3M8YA 5HRTA 3IGYB 4NWJA 5LRMA 2XR9A 3TG0A 5DLWA 2W5XA 4UOPA 5LRNA 3UN5A 3WAXA 4ZG9A 1AJCA 3T02A 4CXKA 1ZEBA 5GOVA 3MK2A 1AJDA 2G9YA 1E33P 4KJGA 4TN0A 5DLTA 1SHNA 4KM4A 5IJSA 2VQRA 2W5SA 1HDHA 2IUCA 4LRDA 5K4PA 1P49A 1HJKA 2GLQA 4MHXA 5DLVA
chains in the Genus database with same CATH superfamily
3NKOA 1URBA 2GSOA 1ALJA 3SZYA 4GTWA 1B8JA 1E3CP 4CYRA 5L0EA 2X98A 1ELZA 1KH9A 1Y6VA 3BDGB 3WAVA 3NKMA 3WAWA 4KJDA 4GTZA 2W5QA 3M7VA 4ZG7A 4KAYA 1N2KA 2XRGA 5EGHA 1ANIA 2ANHA 4CXUA 3T01A 5GRRA 1O99A 1URAA 4LR9A 3DPCA 3UO0A 4LRAA 3MK1A 3E2DA 2GSNA 3B5QA 4MIVA 3TWZA 1KHJA 4UPLA 3CMRA 4N7TA 1EJJA 1KHLA 1AJAA 5INHA 1FSUA 1ZEDA 2W8DA 5TJ3A 4B56A 1E1ZP 2W5TA 3KD8A 3TX0A 1ELYA 2D1GA 5KXAA 3LXQA 1KHKA 4QAXA 3A52A 3NKNA 1ED8A 1SHQA 3SZZA 3WBHA 5L0BA 3WAYA 3BDFA 1ALIA 3BDHA 1N2LA 1ANJA 3UN2A 4NWXA 3MK0A 2GSUA 2IUCB 1EW2A 3M8ZA 2W5VA 1ALHA 1AJBA 1KH5A 4LRCA 4UOOA 3DYCA 4LR8A 5L0KA 3IGZB 1ALKA 5C66A 4LRBA 4FDJA 4UPKA 5AJ9A 4LREA 1ED9A 4KAVA 1EW8A 2QZUA 1ELXA 1HQAA 1O98A 4CYSA 4FDIA 1ZEFA 3T00A 1EW9A 3IDDA 3OT9A 5EGEA 3NKPA 3NKQA 4LR7A 1Y7AA 1K7HA 1EQJA 4UPHA 4CXSA 2ZKTA 1KHNA 3M8WA 3UNYA 4LQYA 3NKRA 5LIAA 5IJQA 4LR2A 1AUKA 3NVLA 2RH6A 4UORA 4UPIA 4GTYA 4ZGAA 4LRFA 5LQQA 2W5RA 1E2SP 3UN3A 1KH4A 1KH7A 4GTXA 1EI6A 2W5WA 3Q3QA 2W8SA 3ED4A 4MY4A 4YR1A 2GA3A 4ZG6A 2IFYA 3BDGA 3M8YA 5HRTA 3IGYB 4NWJA 5LRMA 2XR9A 3TG0A 5DLWA 2W5XA 4UOPA 5LRNA 3UN5A 3WAXA 4ZG9A 1AJCA 3T02A 4CXKA 1ZEBA 5GOVA 3MK2A 1AJDA 2G9YA 1E33P 4KJGA 4TN0A 5DLTA 1SHNA 4KM4A 5IJSA 2VQRA 2W5SA 1HDHA 2IUCA 4LRDA 5K4PA 1P49A 1HJKA 2GLQA 4MHXA 5DLVA
chains in the Genus database with same CATH topology
3NKOA 1URBA 2GSOA 1ALJA 3SZYA 4GTWA 1B8JA 1E3CP 4CYRA 5L0EA 2X98A 1ELZA 1KH9A 1Y6VA 3BDGB 3WAVA 3NKMA 3WAWA 4KJDA 4GTZA 2W5QA 3M7VA 4ZG7A 4KAYA 1N2KA 2XRGA 5EGHA 1ANIA 2ANHA 4CXUA 3T01A 5GRRA 1O99A 1URAA 4LR9A 3DPCA 3UO0A 4LRAA 3MK1A 3E2DA 2GSNA 3B5QA 4MIVA 3TWZA 1KHJA 4UPLA 3CMRA 4N7TA 1EJJA 1KHLA 1AJAA 5INHA 1FSUA 1ZEDA 2W8DA 5TJ3A 4B56A 1E1ZP 2W5TA 3KD8A 3TX0A 1ELYA 2D1GA 5KXAA 3LXQA 1KHKA 4QAXA 3A52A 3NKNA 1ED8A 1SHQA 3SZZA 3WBHA 5L0BA 3WAYA 3BDFA 1ALIA 3BDHA 1N2LA 1ANJA 3UN2A 4NWXA 3MK0A 2GSUA 2IUCB 1EW2A 3M8ZA 2W5VA 1ALHA 1AJBA 1KH5A 4LRCA 4UOOA 3DYCA 4LR8A 5L0KA 3IGZB 1ALKA 5C66A 4LRBA 4FDJA 4UPKA 5AJ9A 4LREA 1ED9A 4KAVA 1EW8A 2QZUA 1ELXA 1HQAA 1O98A 4CYSA 4FDIA 1ZEFA 3T00A 1EW9A 3IDDA 3OT9A 5EGEA 3NKPA 3NKQA 4LR7A 1Y7AA 1K7HA 1EQJA 4UPHA 4CXSA 2ZKTA 1KHNA 3M8WA 3UNYA 4LQYA 3NKRA 5LIAA 5IJQA 4LR2A 1AUKA 3NVLA 2RH6A 4UORA 4UPIA 4GTYA 4ZGAA 4LRFA 5LQQA 2W5RA 1E2SP 3UN3A 1KH4A 1KH7A 4GTXA 1EI6A 2W5WA 3Q3QA 2W8SA 3ED4A 4MY4A 4YR1A 2GA3A 4ZG6A 2IFYA 3BDGA 3M8YA 5HRTA 3IGYB 4NWJA 5LRMA 2XR9A 3TG0A 5DLWA 2W5XA 4UOPA 5LRNA 3UN5A 3WAXA 4ZG9A 1AJCA 3T02A 4CXKA 1ZEBA 5GOVA 3MK2A 1AJDA 2G9YA 1E33P 4KJGA 4TN0A 5DLTA 1SHNA 4KM4A 5IJSA 2VQRA 2W5SA 1HDHA 2IUCA 4LRDA 5K4PA 1P49A 1HJKA 2GLQA 4MHXA 5DLVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NKO A;  1URB A;  2GSO A;  1ALJ A;  3SZY A;  4GTW A;  1B8J A;  1E3C P;  4CYR A;  5L0E A;  2X98 A;  1ELZ A;  1KH9 A;  1Y6V A;  3BDG B;  3WAV A;  3NKM A;  3WAW A;  4KJD A;  4GTZ A;  2W5Q A;  3M7V A;  4ZG7 A;  4KAY A;  1N2K A;  2XRG A;  5EGH A;  1ANI A;  2ANH A;  4CXU A;  3T01 A;  5GRR A;  1O99 A;  1URA A;  4LR9 A;  3DPC A;  3UO0 A;  4LRA A;  3MK1 A;  3E2D A;  2GSN A;  3B5Q A;  4MIV A;  3TWZ A;  1KHJ A;  4UPL A;  3CMR A;  4N7T A;  1EJJ A;  1KHL A;  1AJA A;  5INH A;  1FSU A;  1ZED A;  2W8D A;  5TJ3 A;  4B56 A;  1E1Z P;  2W5T A;  3KD8 A;  3TX0 A;  1ELY A;  2D1G A;  5KXA A;  3LXQ A;  1KHK A;  4QAX A;  3A52 A;  3NKN A;  1ED8 A;  1SHQ A;  3SZZ A;  3WBH A;  5L0B A;  3WAY A;  3BDF A;  1ALI A;  3BDH A;  1N2L A;  1ANJ A;  3UN2 A;  4NWX A;  3MK0 A;  2GSU A;  2IUC B;  1EW2 A;  3M8Z A;  2W5V A;  1ALH A;  1AJB A;  1KH5 A;  4LRC A;  4UOO A;  3DYC A;  4LR8 A;  5L0K A;  3IGZ B;  1ALK A;  5C66 A;  4LRB A;  4FDJ A;  4UPK A;  5AJ9 A;  4LRE A;  1ED9 A;  4KAV A;  1EW8 A;  2QZU A;  1ELX A;  1HQA A;  1O98 A;  4CYS A;  4FDI A;  1ZEF A;  3T00 A;  1EW9 A;  3IDD A;  3OT9 A;  5EGE A;  3NKP A;  3NKQ A;  4LR7 A;  1Y7A A;  1K7H A;  1EQJ A;  4UPH A;  4CXS A;  2ZKT A;  1KHN A;  3M8W A;  3UNY A;  4LQY A;  3NKR A;  5LIA A;  5IJQ A;  4LR2 A;  1AUK A;  3NVL A;  2RH6 A;  4UOR A;  4UPI A;  4GTY A;  4ZGA A;  4LRF A;  5LQQ A;  2W5R A;  1E2S P;  3UN3 A;  1KH4 A;  1KH7 A;  4GTX A;  1EI6 A;  2W5W A;  3Q3Q A;  2W8S A;  3ED4 A;  4MY4 A;  4YR1 A;  2GA3 A;  4ZG6 A;  2IFY A;  3BDG A;  3M8Y A;  5HRT A;  3IGY B;  4NWJ A;  5LRM A;  2XR9 A;  3TG0 A;  5DLW A;  2W5X A;  4UOP A;  5LRN A;  3UN5 A;  3WAX A;  4ZG9 A;  1AJC A;  3T02 A;  4CXK A;  1ZEB A;  5GOV A;  3MK2 A;  1AJD A;  2G9Y A;  1E33 P;  4KJG A;  4TN0 A;  5DLT A;  1SHN A;  4KM4 A;  5IJS A;  2VQR A;  2W5S A;  1HDH A;  2IUC A;  4LRD A;  5K4P A;  1P49 A;  1HJK A;  2GLQ A;  4MHX A;  5DLV A; 
#chains in the Genus database with same CATH topology
 3NKO A;  1URB A;  2GSO A;  1ALJ A;  3SZY A;  4GTW A;  1B8J A;  1E3C P;  4CYR A;  5L0E A;  2X98 A;  1ELZ A;  1KH9 A;  1Y6V A;  3BDG B;  3WAV A;  3NKM A;  3WAW A;  4KJD A;  4GTZ A;  2W5Q A;  3M7V A;  4ZG7 A;  4KAY A;  1N2K A;  2XRG A;  5EGH A;  1ANI A;  2ANH A;  4CXU A;  3T01 A;  5GRR A;  1O99 A;  1URA A;  4LR9 A;  3DPC A;  3UO0 A;  4LRA A;  3MK1 A;  3E2D A;  2GSN A;  3B5Q A;  4MIV A;  3TWZ A;  1KHJ A;  4UPL A;  3CMR A;  4N7T A;  1EJJ A;  1KHL A;  1AJA A;  5INH A;  1FSU A;  1ZED A;  2W8D A;  5TJ3 A;  4B56 A;  1E1Z P;  2W5T A;  3KD8 A;  3TX0 A;  1ELY A;  2D1G A;  5KXA A;  3LXQ A;  1KHK A;  4QAX A;  3A52 A;  3NKN A;  1ED8 A;  1SHQ A;  3SZZ A;  3WBH A;  5L0B A;  3WAY A;  3BDF A;  1ALI A;  3BDH A;  1N2L A;  1ANJ A;  3UN2 A;  4NWX A;  3MK0 A;  2GSU A;  2IUC B;  1EW2 A;  3M8Z A;  2W5V A;  1ALH A;  1AJB A;  1KH5 A;  4LRC A;  4UOO A;  3DYC A;  4LR8 A;  5L0K A;  3IGZ B;  1ALK A;  5C66 A;  4LRB A;  4FDJ A;  4UPK A;  5AJ9 A;  4LRE A;  1ED9 A;  4KAV A;  1EW8 A;  2QZU A;  1ELX A;  1HQA A;  1O98 A;  4CYS A;  4FDI A;  1ZEF A;  3T00 A;  1EW9 A;  3IDD A;  3OT9 A;  5EGE A;  3NKP A;  3NKQ A;  4LR7 A;  1Y7A A;  1K7H A;  1EQJ A;  4UPH A;  4CXS A;  2ZKT A;  1KHN A;  3M8W A;  3UNY A;  4LQY A;  3NKR A;  5LIA A;  5IJQ A;  4LR2 A;  1AUK A;  3NVL A;  2RH6 A;  4UOR A;  4UPI A;  4GTY A;  4ZGA A;  4LRF A;  5LQQ A;  2W5R A;  1E2S P;  3UN3 A;  1KH4 A;  1KH7 A;  4GTX A;  1EI6 A;  2W5W A;  3Q3Q A;  2W8S A;  3ED4 A;  4MY4 A;  4YR1 A;  2GA3 A;  4ZG6 A;  2IFY A;  3BDG A;  3M8Y A;  5HRT A;  3IGY B;  4NWJ A;  5LRM A;  2XR9 A;  3TG0 A;  5DLW A;  2W5X A;  4UOP A;  5LRN A;  3UN5 A;  3WAX A;  4ZG9 A;  1AJC A;  3T02 A;  4CXK A;  1ZEB A;  5GOV A;  3MK2 A;  1AJD A;  2G9Y A;  1E33 P;  4KJG A;  4TN0 A;  5DLT A;  1SHN A;  4KM4 A;  5IJS A;  2VQR A;  2W5S A;  1HDH A;  2IUC A;  4LRD A;  5K4P A;  1P49 A;  1HJK A;  2GLQ A;  4MHX A;  5DLV A; 
#chains in the Genus database with same CATH homology
 3NKO A;  1URB A;  2GSO A;  1ALJ A;  3SZY A;  4GTW A;  1B8J A;  1E3C P;  4CYR A;  5L0E A;  2X98 A;  1ELZ A;  1KH9 A;  1Y6V A;  3BDG B;  3WAV A;  3NKM A;  3WAW A;  4KJD A;  4GTZ A;  2W5Q A;  3M7V A;  4ZG7 A;  4KAY A;  1N2K A;  2XRG A;  5EGH A;  1ANI A;  2ANH A;  4CXU A;  3T01 A;  5GRR A;  1O99 A;  1URA A;  4LR9 A;  3DPC A;  3UO0 A;  4LRA A;  3MK1 A;  3E2D A;  2GSN A;  3B5Q A;  4MIV A;  3TWZ A;  1KHJ A;  4UPL A;  3CMR A;  4N7T A;  1EJJ A;  1KHL A;  1AJA A;  5INH A;  1FSU A;  1ZED A;  2W8D A;  5TJ3 A;  4B56 A;  1E1Z P;  2W5T A;  3KD8 A;  3TX0 A;  1ELY A;  2D1G A;  5KXA A;  3LXQ A;  1KHK A;  4QAX A;  3A52 A;  3NKN A;  1ED8 A;  1SHQ A;  3SZZ A;  3WBH A;  5L0B A;  3WAY A;  3BDF A;  1ALI A;  3BDH A;  1N2L A;  1ANJ A;  3UN2 A;  4NWX A;  3MK0 A;  2GSU A;  2IUC B;  1EW2 A;  3M8Z A;  2W5V A;  1ALH A;  1AJB A;  1KH5 A;  4LRC A;  4UOO A;  3DYC A;  4LR8 A;  5L0K A;  3IGZ B;  1ALK A;  5C66 A;  4LRB A;  4FDJ A;  4UPK A;  5AJ9 A;  4LRE A;  1ED9 A;  4KAV A;  1EW8 A;  2QZU A;  1ELX A;  1HQA A;  1O98 A;  4CYS A;  4FDI A;  1ZEF A;  3T00 A;  1EW9 A;  3IDD A;  3OT9 A;  5EGE A;  3NKP A;  3NKQ A;  4LR7 A;  1Y7A A;  1K7H A;  1EQJ A;  4UPH A;  4CXS A;  2ZKT A;  1KHN A;  3M8W A;  3UNY A;  4LQY A;  3NKR A;  5LIA A;  5IJQ A;  4LR2 A;  1AUK A;  3NVL A;  2RH6 A;  4UOR A;  4UPI A;  4GTY A;  4ZGA A;  4LRF A;  5LQQ A;  2W5R A;  1E2S P;  3UN3 A;  1KH4 A;  1KH7 A;  4GTX A;  1EI6 A;  2W5W A;  3Q3Q A;  2W8S A;  3ED4 A;  4MY4 A;  4YR1 A;  2GA3 A;  4ZG6 A;  2IFY A;  3BDG A;  3M8Y A;  5HRT A;  3IGY B;  4NWJ A;  5LRM A;  2XR9 A;  3TG0 A;  5DLW A;  2W5X A;  4UOP A;  5LRN A;  3UN5 A;  3WAX A;  4ZG9 A;  1AJC A;  3T02 A;  4CXK A;  1ZEB A;  5GOV A;  3MK2 A;  1AJD A;  2G9Y A;  1E33 P;  4KJG A;  4TN0 A;  5DLT A;  1SHN A;  4KM4 A;  5IJS A;  2VQR A;  2W5S A;  1HDH A;  2IUC A;  4LRD A;  5K4P A;  1P49 A;  1HJK A;  2GLQ A;  4MHX A;  5DLV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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