4MIVA

Crystal structure of sulfamidase, crystal form l
Total Genus 169
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
169
Knots found
sequence length
484
structure length
483
Chain Sequence
PRNALLLLADDGGFESGAYNNSAIATPHLDALARRSLLFRNAFTSVSSSPSRASLLTGLPQHQNGMYGLHQDVHHFNSFDKVRSLPLLLSQAGVRTGIIGKKHVGPETVYPFDFAYTEENGSVLQVGRNITRIKLLVRKFLQTQDDRPFFLYVAFHDPHRCGHSQPQYGTFCEKFGNGESGMGRIPDWTPQAYDPLDVLVPYFVPNTPAARADLAAQYTTVGRMDQGVGLVLQELRDAGVLNDTLVIFTSDNGIPFPSGRTNLYWPGTAEPLLVSSPEHPKRWGQVSEAYVSLLDLTPTILDWFSIPYPSYAIFGSKTIHLTGRSLLPALEAEPLWATVFGSQSHHEVTMSYPMRSVQHRHFRLVHNLNFKMPFPIDQDFYVSPTFQDLLNRTTAGQPTGWYKDLRHYYYRARWELYDRSRDPHETQNLATDPRFAQLLEMLRDQLAKWQWETHDPWVCAPDGVLEEKLSPQCQPLHNELRSH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords N-sulphoglucosamine sulphohydrolase
publication title Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA.
pubmed doi rcsb
source organism Homo sapiens
total genus 169
structure length 483
sequence length 484
chains with identical sequence B, C, D, E, F, G, H
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.10.1.1: N-sulfoglucosamine sulfohydrolase.
pdb deposition date 2013-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
A PF16347 DUF4976 Domain of unknown function (DUF4976)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4mivA01
3TWZA 1KHNA 1URBA 4B56A 1SHNA 3NKQA 3NKOA 2QZUA 3DYCA 2IFYA 3TX0A 3WBHA 1O98A 4UPLA 3MK0A 5GOVA 3A52A 3UN3A 3T00A 4CXKA 5INHA 4KJDA 2W5VA 5IJQA 3WAVA 5EGHA 4LR9A 3BDGB 1ANJA 1EQJA 1E33P 2XRGA 3Q3QA 4NWXA 3MK1A 3KD8A 3UO0A 2W5QA 5HRTA 4GTZA 2W5SA 1FSUA 4LRCA 5KXAA 1B8JA 4LREA 5DLWA 4ZGAA 3T02A 1N2KA 3DPCA 2W5RA 1KHJA 3IDDA 5TJ3A 2GLQA 5L0KA 1EW2A 1ED9A 3SZYA 4MIVA 5K4PA 5DLTA 1EJJA 2IUCB 3NKMA 4MHXA 4LRDA 4LR2A 5GRRA 1EW8A 1HJKA 3CMRA 3MK2A 4GTXA 4KJGA 1O99A 2GSUA 3BDGA 1KH4A 5LRMA 1ZEFA 3NKNA 1KH9A 1KHLA 3IGYB 4KM4A 5IJSA 1Y6VA 2W5TA 4QAXA 1E3CP 5LRNA 3TG0A 2W8SA 1ELZA 2D1GA 1AJDA 4UOPA 3M8WA 3WAWA 4ZG7A 5LIAA 1KHKA 1HDHA 1ELYA 4GTYA 4UPHA 3NKRA 3NVLA 2VQRA 1AJBA 5LQQA 4NWJA 4ZG9A 1AUKA 1ALKA 1E2SP 3IGZB 2W5WA 1AJAA 4CYSA 1EW9A 5L0BA 1SHQA 4KAYA 3BDFA 4LR7A 4FDJA 4LRBA 2IUCA 3ED4A 4N7TA 1ANIA 2GSNA 1ELXA 1AJCA 3OT9A 1ALIA 5C66A 4CXSA 4MY4A 3WAYA 4LQYA 3NKPA 4LR8A 3T01A 5L0EA 1ZEBA 1URAA 1P49A 3E2DA 1HQAA 2ANHA 4LRFA 3M7VA 4CYRA 1ALHA 5EGEA 3UN2A 4ZG6A 1N2LA 5AJ9A 3SZZA 4FDIA 3WAXA 4KAVA 4YR1A 4UOOA 1KH5A 2W5XA 4TN0A 1KH7A 5DLVA 1Y7AA 1ALJA 3M8ZA 1EI6A 1ZEDA 2W8DA 1K7HA 3UNYA 1ED8A 2RH6A 3BDHA 2XR9A 4UPIA 4GTWA 2G9YA 2X98A 3B5QA 4UPKA 3UN5A 4LRAA 4UORA 2ZKTA 3LXQA 2GA3A 1E1ZP 4CXUA 3M8YA 2GSOA
chains in the Genus database with same CATH superfamily
3TWZA 1KHNA 1URBA 4B56A 1SHNA 3NKQA 3NKOA 2QZUA 3DYCA 2IFYA 3TX0A 3WBHA 1O98A 4UPLA 3MK0A 5GOVA 3A52A 3UN3A 3T00A 4CXKA 5INHA 4KJDA 2W5VA 5IJQA 3WAVA 5EGHA 4LR9A 3BDGB 1ANJA 1EQJA 1E33P 2XRGA 3Q3QA 4NWXA 3MK1A 3KD8A 3UO0A 2W5QA 5HRTA 4GTZA 2W5SA 1FSUA 4LRCA 5KXAA 1B8JA 4LREA 5DLWA 4ZGAA 3T02A 1N2KA 3DPCA 2W5RA 1KHJA 3IDDA 5TJ3A 2GLQA 5L0KA 1EW2A 1ED9A 3SZYA 4MIVA 5K4PA 5DLTA 1EJJA 2IUCB 3NKMA 4MHXA 4LRDA 4LR2A 5GRRA 1EW8A 1HJKA 3CMRA 3MK2A 4GTXA 4KJGA 1O99A 2GSUA 3BDGA 1KH4A 5LRMA 1ZEFA 3NKNA 1KH9A 1KHLA 3IGYB 4KM4A 5IJSA 1Y6VA 2W5TA 4QAXA 1E3CP 5LRNA 3TG0A 2W8SA 1ELZA 2D1GA 1AJDA 4UOPA 3M8WA 3WAWA 4ZG7A 5LIAA 1KHKA 1HDHA 1ELYA 4GTYA 4UPHA 3NKRA 3NVLA 2VQRA 1AJBA 5LQQA 4NWJA 4ZG9A 1AUKA 1ALKA 1E2SP 3IGZB 2W5WA 1AJAA 4CYSA 1EW9A 5L0BA 1SHQA 4KAYA 3BDFA 4LR7A 4FDJA 4LRBA 2IUCA 3ED4A 4N7TA 1ANIA 2GSNA 1ELXA 1AJCA 3OT9A 1ALIA 5C66A 4CXSA 4MY4A 3WAYA 4LQYA 3NKPA 4LR8A 3T01A 5L0EA 1ZEBA 1URAA 1P49A 3E2DA 1HQAA 2ANHA 4LRFA 3M7VA 4CYRA 1ALHA 5EGEA 3UN2A 4ZG6A 1N2LA 5AJ9A 3SZZA 4FDIA 3WAXA 4KAVA 4YR1A 4UOOA 1KH5A 2W5XA 4TN0A 1KH7A 5DLVA 1Y7AA 1ALJA 3M8ZA 1EI6A 1ZEDA 2W8DA 1K7HA 3UNYA 1ED8A 2RH6A 3BDHA 2XR9A 4UPIA 4GTWA 2G9YA 2X98A 3B5QA 4UPKA 3UN5A 4LRAA 4UORA 2ZKTA 3LXQA 2GA3A 1E1ZP 4CXUA 3M8YA 2GSOA
chains in the Genus database with same CATH topology
3TWZA 1KHNA 1URBA 4B56A 1SHNA 3NKQA 3NKOA 2QZUA 3DYCA 2IFYA 3TX0A 3WBHA 1O98A 4UPLA 3MK0A 5GOVA 3A52A 3UN3A 3T00A 4CXKA 5INHA 4KJDA 2W5VA 5IJQA 3WAVA 5EGHA 4LR9A 3BDGB 1ANJA 1EQJA 1E33P 2XRGA 3Q3QA 4NWXA 3MK1A 3KD8A 3UO0A 2W5QA 5HRTA 4GTZA 2W5SA 1FSUA 4LRCA 5KXAA 1B8JA 4LREA 5DLWA 4ZGAA 3T02A 1N2KA 3DPCA 2W5RA 1KHJA 3IDDA 5TJ3A 2GLQA 5L0KA 1EW2A 1ED9A 3SZYA 4MIVA 5K4PA 5DLTA 1EJJA 2IUCB 3NKMA 4MHXA 4LRDA 4LR2A 5GRRA 1EW8A 1HJKA 3CMRA 3MK2A 4GTXA 4KJGA 1O99A 2GSUA 3BDGA 1KH4A 5LRMA 1ZEFA 3NKNA 1KH9A 1KHLA 3IGYB 4KM4A 5IJSA 1Y6VA 2W5TA 4QAXA 1E3CP 5LRNA 3TG0A 2W8SA 1ELZA 2D1GA 1AJDA 4UOPA 3M8WA 3WAWA 4ZG7A 5LIAA 1KHKA 1HDHA 1ELYA 4GTYA 4UPHA 3NKRA 3NVLA 2VQRA 1AJBA 5LQQA 4NWJA 4ZG9A 1AUKA 1ALKA 1E2SP 3IGZB 2W5WA 1AJAA 4CYSA 1EW9A 5L0BA 1SHQA 4KAYA 3BDFA 4LR7A 4FDJA 4LRBA 2IUCA 3ED4A 4N7TA 1ANIA 2GSNA 1ELXA 1AJCA 3OT9A 1ALIA 5C66A 4CXSA 4MY4A 3WAYA 4LQYA 3NKPA 4LR8A 3T01A 5L0EA 1ZEBA 1URAA 1P49A 3E2DA 1HQAA 2ANHA 4LRFA 3M7VA 4CYRA 1ALHA 5EGEA 3UN2A 4ZG6A 1N2LA 5AJ9A 3SZZA 4FDIA 3WAXA 4KAVA 4YR1A 4UOOA 1KH5A 2W5XA 4TN0A 1KH7A 5DLVA 1Y7AA 1ALJA 3M8ZA 1EI6A 1ZEDA 2W8DA 1K7HA 3UNYA 1ED8A 2RH6A 3BDHA 2XR9A 4UPIA 4GTWA 2G9YA 2X98A 3B5QA 4UPKA 3UN5A 4LRAA 4UORA 2ZKTA 3LXQA 2GA3A 1E1ZP 4CXUA 3M8YA 2GSOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TWZ A;  1KHN A;  1URB A;  4B56 A;  1SHN A;  3NKQ A;  3NKO A;  2QZU A;  3DYC A;  2IFY A;  3TX0 A;  3WBH A;  1O98 A;  4UPL A;  3MK0 A;  5GOV A;  3A52 A;  3UN3 A;  3T00 A;  4CXK A;  5INH A;  4KJD A;  2W5V A;  5IJQ A;  3WAV A;  5EGH A;  4LR9 A;  3BDG B;  1ANJ A;  1EQJ A;  1E33 P;  2XRG A;  3Q3Q A;  4NWX A;  3MK1 A;  3KD8 A;  3UO0 A;  2W5Q A;  5HRT A;  4GTZ A;  2W5S A;  1FSU A;  4LRC A;  5KXA A;  1B8J A;  4LRE A;  5DLW A;  4ZGA A;  3T02 A;  1N2K A;  3DPC A;  2W5R A;  1KHJ A;  3IDD A;  5TJ3 A;  2GLQ A;  5L0K A;  1EW2 A;  1ED9 A;  3SZY A;  4MIV A;  5K4P A;  5DLT A;  1EJJ A;  2IUC B;  3NKM A;  4MHX A;  4LRD A;  4LR2 A;  5GRR A;  1EW8 A;  1HJK A;  3CMR A;  3MK2 A;  4GTX A;  4KJG A;  1O99 A;  2GSU A;  3BDG A;  1KH4 A;  5LRM A;  1ZEF A;  3NKN A;  1KH9 A;  1KHL A;  3IGY B;  4KM4 A;  5IJS A;  1Y6V A;  2W5T A;  4QAX A;  1E3C P;  5LRN A;  3TG0 A;  2W8S A;  1ELZ A;  2D1G A;  1AJD A;  4UOP A;  3M8W A;  3WAW A;  4ZG7 A;  5LIA A;  1KHK A;  1HDH A;  1ELY A;  4GTY A;  4UPH A;  3NKR A;  3NVL A;  2VQR A;  1AJB A;  5LQQ A;  4NWJ A;  4ZG9 A;  1AUK A;  1ALK A;  1E2S P;  3IGZ B;  2W5W A;  1AJA A;  4CYS A;  1EW9 A;  5L0B A;  1SHQ A;  4KAY A;  3BDF A;  4LR7 A;  4FDJ A;  4LRB A;  2IUC A;  3ED4 A;  4N7T A;  1ANI A;  2GSN A;  1ELX A;  1AJC A;  3OT9 A;  1ALI A;  5C66 A;  4CXS A;  4MY4 A;  3WAY A;  4LQY A;  3NKP A;  4LR8 A;  3T01 A;  5L0E A;  1ZEB A;  1URA A;  1P49 A;  3E2D A;  1HQA A;  2ANH A;  4LRF A;  3M7V A;  4CYR A;  1ALH A;  5EGE A;  3UN2 A;  4ZG6 A;  1N2L A;  5AJ9 A;  3SZZ A;  4FDI A;  3WAX A;  4KAV A;  4YR1 A;  4UOO A;  1KH5 A;  2W5X A;  4TN0 A;  1KH7 A;  5DLV A;  1Y7A A;  1ALJ A;  3M8Z A;  1EI6 A;  1ZED A;  2W8D A;  1K7H A;  3UNY A;  1ED8 A;  2RH6 A;  3BDH A;  2XR9 A;  4UPI A;  4GTW A;  2G9Y A;  2X98 A;  3B5Q A;  4UPK A;  3UN5 A;  4LRA A;  4UOR A;  2ZKT A;  3LXQ A;  2GA3 A;  1E1Z P;  4CXU A;  3M8Y A;  2GSO A; 
#chains in the Genus database with same CATH topology
 3TWZ A;  1KHN A;  1URB A;  4B56 A;  1SHN A;  3NKQ A;  3NKO A;  2QZU A;  3DYC A;  2IFY A;  3TX0 A;  3WBH A;  1O98 A;  4UPL A;  3MK0 A;  5GOV A;  3A52 A;  3UN3 A;  3T00 A;  4CXK A;  5INH A;  4KJD A;  2W5V A;  5IJQ A;  3WAV A;  5EGH A;  4LR9 A;  3BDG B;  1ANJ A;  1EQJ A;  1E33 P;  2XRG A;  3Q3Q A;  4NWX A;  3MK1 A;  3KD8 A;  3UO0 A;  2W5Q A;  5HRT A;  4GTZ A;  2W5S A;  1FSU A;  4LRC A;  5KXA A;  1B8J A;  4LRE A;  5DLW A;  4ZGA A;  3T02 A;  1N2K A;  3DPC A;  2W5R A;  1KHJ A;  3IDD A;  5TJ3 A;  2GLQ A;  5L0K A;  1EW2 A;  1ED9 A;  3SZY A;  4MIV A;  5K4P A;  5DLT A;  1EJJ A;  2IUC B;  3NKM A;  4MHX A;  4LRD A;  4LR2 A;  5GRR A;  1EW8 A;  1HJK A;  3CMR A;  3MK2 A;  4GTX A;  4KJG A;  1O99 A;  2GSU A;  3BDG A;  1KH4 A;  5LRM A;  1ZEF A;  3NKN A;  1KH9 A;  1KHL A;  3IGY B;  4KM4 A;  5IJS A;  1Y6V A;  2W5T A;  4QAX A;  1E3C P;  5LRN A;  3TG0 A;  2W8S A;  1ELZ A;  2D1G A;  1AJD A;  4UOP A;  3M8W A;  3WAW A;  4ZG7 A;  5LIA A;  1KHK A;  1HDH A;  1ELY A;  4GTY A;  4UPH A;  3NKR A;  3NVL A;  2VQR A;  1AJB A;  5LQQ A;  4NWJ A;  4ZG9 A;  1AUK A;  1ALK A;  1E2S P;  3IGZ B;  2W5W A;  1AJA A;  4CYS A;  1EW9 A;  5L0B A;  1SHQ A;  4KAY A;  3BDF A;  4LR7 A;  4FDJ A;  4LRB A;  2IUC A;  3ED4 A;  4N7T A;  1ANI A;  2GSN A;  1ELX A;  1AJC A;  3OT9 A;  1ALI A;  5C66 A;  4CXS A;  4MY4 A;  3WAY A;  4LQY A;  3NKP A;  4LR8 A;  3T01 A;  5L0E A;  1ZEB A;  1URA A;  1P49 A;  3E2D A;  1HQA A;  2ANH A;  4LRF A;  3M7V A;  4CYR A;  1ALH A;  5EGE A;  3UN2 A;  4ZG6 A;  1N2L A;  5AJ9 A;  3SZZ A;  4FDI A;  3WAX A;  4KAV A;  4YR1 A;  4UOO A;  1KH5 A;  2W5X A;  4TN0 A;  1KH7 A;  5DLV A;  1Y7A A;  1ALJ A;  3M8Z A;  1EI6 A;  1ZED A;  2W8D A;  1K7H A;  3UNY A;  1ED8 A;  2RH6 A;  3BDH A;  2XR9 A;  4UPI A;  4GTW A;  2G9Y A;  2X98 A;  3B5Q A;  4UPK A;  3UN5 A;  4LRA A;  4UOR A;  2ZKT A;  3LXQ A;  2GA3 A;  1E1Z P;  4CXU A;  3M8Y A;  2GSO A; 
#chains in the Genus database with same CATH homology
 3TWZ A;  1KHN A;  1URB A;  4B56 A;  1SHN A;  3NKQ A;  3NKO A;  2QZU A;  3DYC A;  2IFY A;  3TX0 A;  3WBH A;  1O98 A;  4UPL A;  3MK0 A;  5GOV A;  3A52 A;  3UN3 A;  3T00 A;  4CXK A;  5INH A;  4KJD A;  2W5V A;  5IJQ A;  3WAV A;  5EGH A;  4LR9 A;  3BDG B;  1ANJ A;  1EQJ A;  1E33 P;  2XRG A;  3Q3Q A;  4NWX A;  3MK1 A;  3KD8 A;  3UO0 A;  2W5Q A;  5HRT A;  4GTZ A;  2W5S A;  1FSU A;  4LRC A;  5KXA A;  1B8J A;  4LRE A;  5DLW A;  4ZGA A;  3T02 A;  1N2K A;  3DPC A;  2W5R A;  1KHJ A;  3IDD A;  5TJ3 A;  2GLQ A;  5L0K A;  1EW2 A;  1ED9 A;  3SZY A;  4MIV A;  5K4P A;  5DLT A;  1EJJ A;  2IUC B;  3NKM A;  4MHX A;  4LRD A;  4LR2 A;  5GRR A;  1EW8 A;  1HJK A;  3CMR A;  3MK2 A;  4GTX A;  4KJG A;  1O99 A;  2GSU A;  3BDG A;  1KH4 A;  5LRM A;  1ZEF A;  3NKN A;  1KH9 A;  1KHL A;  3IGY B;  4KM4 A;  5IJS A;  1Y6V A;  2W5T A;  4QAX A;  1E3C P;  5LRN A;  3TG0 A;  2W8S A;  1ELZ A;  2D1G A;  1AJD A;  4UOP A;  3M8W A;  3WAW A;  4ZG7 A;  5LIA A;  1KHK A;  1HDH A;  1ELY A;  4GTY A;  4UPH A;  3NKR A;  3NVL A;  2VQR A;  1AJB A;  5LQQ A;  4NWJ A;  4ZG9 A;  1AUK A;  1ALK A;  1E2S P;  3IGZ B;  2W5W A;  1AJA A;  4CYS A;  1EW9 A;  5L0B A;  1SHQ A;  4KAY A;  3BDF A;  4LR7 A;  4FDJ A;  4LRB A;  2IUC A;  3ED4 A;  4N7T A;  1ANI A;  2GSN A;  1ELX A;  1AJC A;  3OT9 A;  1ALI A;  5C66 A;  4CXS A;  4MY4 A;  3WAY A;  4LQY A;  3NKP A;  4LR8 A;  3T01 A;  5L0E A;  1ZEB A;  1URA A;  1P49 A;  3E2D A;  1HQA A;  2ANH A;  4LRF A;  3M7V A;  4CYR A;  1ALH A;  5EGE A;  3UN2 A;  4ZG6 A;  1N2L A;  5AJ9 A;  3SZZ A;  4FDI A;  3WAX A;  4KAV A;  4YR1 A;  4UOO A;  1KH5 A;  2W5X A;  4TN0 A;  1KH7 A;  5DLV A;  1Y7A A;  1ALJ A;  3M8Z A;  1EI6 A;  1ZED A;  2W8D A;  1K7H A;  3UNY A;  1ED8 A;  2RH6 A;  3BDH A;  2XR9 A;  4UPI A;  4GTW A;  2G9Y A;  2X98 A;  3B5Q A;  4UPK A;  3UN5 A;  4LRA A;  4UOR A;  2ZKT A;  3LXQ A;  2GA3 A;  1E1Z P;  4CXU A;  3M8Y A;  2GSO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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