2X98A

H.salinarum alkaline phosphatase
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
Knots found
sequence length
430
structure length
430
Chain Sequence
b'ASPAANAIAYIVDGMGQTQISAARYLNAYKTAPERFPLNVSPAETPTGFDAFSSRGSMTTFPDDPYETTTDSAAAATAFASGVKTYNGAIGGVQTSGGGFQRVDTVLERASAQGYATGLITTTEATHATPAAFAAHVEDRGNQTEIARQYIEETQPDVILGGQRRDFEADASNGGTLVDAARDNGYTIAETAAELDAVDDPPVLGLFSQESHLDYYLDRKNDPENTQPNLDAMVDAGVDLLSSAGDPDKGFFLLVESGRVDHAGHANYPAQVAEQYEATQVAGQLVEYAETTAEPTFLVSTGDHECGGLTLGRDSPYEVEYDVLAAQKATTSRLRDLLAGVRSADELESIVAAHTGITALTDREVAKLRDAPGSISTILAERAGIAFTTDGHTGTDVPVFAHGPNAARFDAARDNTAVADALAAALGVSL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALKALINE PHOSPHATASE
publication title Structural and Biochemical Characterization of a Halophilic Archaeal Alkaline Phosphatase.
pubmed doi rcsb
source organism Halobacterium salinarum
molecule tags Hydrolase
total genus 149
structure length 430
sequence length 430
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2010-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.60.40 Mainly Alpha Orthogonal Bundle Diphtheria Toxin Repressor; domain 2 Diphtheria Toxin Repressor; domain 2 2x98A02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2x98A01
1AUKA 4B56A 1AJBA 3BDGA 4GTXA 4UOOA 4GTZA 4MY4A 2W5TA 2ANHA 3M8ZA 3BDHA 1SHNA 3MK2A 3WAWA 2G9YA 4CXSA 1KH4A 4ZGAA 3UN5A 3BDFA 2GA3A 3SZZA 1KHNA 4MHXA 3NKRA 3NKNA 4LR2A 4CXUA 4ZG6A 1AJCA 1O98A 1URAA 4CYSA 3UN3A 2W5RA 2GLQA 3M7VA 5INHA 4LREA 5GOVA 4LRCA 1KH5A 5L0BA 3IGZB 1HQAA 4QAXA 4LRFA 3SZYA 5DLWA 3TWZA 1ALKA 3DYCA 3T01A 2W5WA 5DLVA 5K4PA 5DLTA 4LR9A 4LQYA 1KHKA 4TN0A 3CMRA 2VQRA 1N2LA 4LR7A 5L0KA 1HJKA 2W5XA 4UOPA 3IDDA 1O99A 3NVLA 1E3CP 3MK1A 3MK0A 4UPKA 3OT9A 4NWXA 5GRRA 1P49A 1K7HA 3B5QA 1N2KA 1AJAA 2W8DA 1EW9A 3WAXA 2GSOA 2IFYA 1E2SP 3NKOA 4UPLA 3KD8A 3NKPA 5C66A 5KXAA 2W5SA 1ZEFA 1KHJA 1ZEBA 5EGEA 3E2DA 2GSNA 2W5QA 3M8YA 4ZG9A 5TJ3A 2W5VA 4MIVA 3WAVA 1ALJA 1B8JA 5L0EA 1EJJA 1KH9A 2W8SA 1EW8A 1URBA 1ELZA 1Y6VA 3TX0A 4NWJA 3M8WA 4GTWA 4UORA 4KJDA 2XR9A 4CYRA 3DPCA 5EGHA 3IGYB 1KH7A 2X98A 1EW2A 1ANJA 4GTYA 4LRDA 4UPHA 3UO0A 1ZEDA 4ZG7A 1ED9A 1AJDA 4FDIA 1ANIA 4KJGA 3WAYA 1ELXA 2ZKTA 4UPIA 2IUCA 5LRNA 3BDGB 1ED8A 2IUCB 3UNYA 3LXQA 4FDJA 5AJ9A 4LR8A 3TG0A 1HDHA 1E33P 3ED4A 5IJQA 4LRAA 1ALHA 3Q3QA 3NKQA 3UN2A 5HRTA 1EQJA 4N7TA 3NKMA 4KAVA 1ELYA 5LQQA 2GSUA 4KAYA 2XRGA 1ALIA 5LIAA 2QZUA 2RH6A 1KHLA 3WBHA 5IJSA 2D1GA 5LRMA 1Y7AA 1E1ZP 3A52A 1SHQA 1FSUA 1EI6A 4KM4A 4LRBA 3T02A 4YR1A 3T00A 4CXKA
chains in the Genus database with same CATH superfamily
1AUKA 2F5EA 4B56A 1AJBA 3BDGA 4GTXA 4UOOA 4GTZA 1G3YA 2W5TA 2ANHA 4MY4A 3M8ZA 3BDHA 1SHNA 3MK2A 3WAWA 3JAMR 2G9YA 4CXSA 1P92A 1KH4A 4ZGAA 3UN5A 3BDFA 2TDXA 2GA3A 3SZZA 1KHNA 4MHXA 3NKRA 3NKNA 2F5DA 4LR2A 4CXUA 1G3WA 4ZG6A 1AJCA 1O98A 1URAA 4CYSA 3UN3A 2W5RA 2GLQA 3M7VA 2EV6A 5INHA 4LREA 5GOVA 1G3SA 2MVTA 1KH5A 4LRCA 3IGZB 5L0BA 1HQAA 4QAXA 4LRFA 3SZYA 1U8RA 5A2QR 5DLWA 3TWZA 1ALKA 3DYCA 3T01A 2W5WA 5DLVA 2F5CA 5DLTA 4LR9A 4LQYA 5K4PA 1BI2A 1KHKA 4TN0A 3CMRA 2VQRA 1B1BA 1N2LA 4LR7A 5L0KA 1HJKA 1ON2A 2W5XA 4UOPA 3IDDA 1XCVA 1O99A 3NVLA 1BI0A 1DDNA 1E3CP 3MK1A 2ISZA 3MK0A 1FWZA 4UPKA 3OT9A 4NWXA 5GRRA 1P49A 1K7HA 3J7AW 3B5QA 4HV6A 1N2KA 1AJAA 4HV5A 5FLXR 2W8DA 4O6JA 1EW9A 2M35A 3WAXA 2F5FA 2GSOA 2IFYA 1E2SP 3NKOA 4UPLA 3J80R 3KD8A 3NKPA 5C66A 5KXAA 2QQ9A 2W5SA 1KHJA 1ZEFA 1ZEBA 2QQAA 5EGEA 3J81R 3E2DA 1C0WA 2GSNA 2DTRA 2W5QA 3M8YA 4ZG9A 5TJ3A 3R61A 1FX7A 2W5VA 4MIVA 1B8JA 3WAVA 1ALJA 5L0EA 1EJJA 1G3TA 1BI1A 4HX7A 1KH9A 2W8SA 1EW8A 1URBA 1ELZA 1Y6VA 3TX0A 4NWJA 2HYGD 3M8WA 4GTWA 4KJDA 2XR9A 4UORA 4CYRA 3DPCA 5EGHA 3IGYB 2EV5A 2X98A 1EW2A 1ANJA 1KH7A 4GTYA 4LRDA 4UPHA 4HX4A 1ZEDA 3UO0A 4ZG7A 1ED9A 4HX8A 1AJDA 4FDIA 1F5TA 1ANIA 4KJGA 3WAYA 1ELXA 2ZKTA 2MUNA 4UPIA 2IUCA 1DPRA 5LRNA 3BDGB 1ED8A 2IUCB 3UNYA 3LXQA 4FDJA 5AJ9A 2QQBA 4LR8A 1ON1A 1HDHA 1E33P 3ED4A 5IJQA 3TG0A 4LRAA 1ALHA 3Q3QA 3NKQA 3UN2A 5HRTA 1EQJA 4O5VA 4N7TA 3NKMA 4KAVA 1ELYA 2HYFA 5LQQA 2GSUA 2P0TA 3R60A 2H09A 4KAYA 2XRGA 1ALIA 1RQ6A 5LIAA 2QZUA 2RH6A 1KHLA 3WBHA 5IJSA 2D1GA 5IT9R 5LRMA 1Y7AA 1E1ZP 3A52A 3GLXA 1FSUA 1SHQA 1EI6A 4KM4A 4LRBA 2MZ4A 3T02A 4YR1A 3T00A 4CXKA 2EV0A 1BI3A
chains in the Genus database with same CATH topology
1AUKA 4B56A 1AJBA 3BDGA 4GTXA 4UOOA 4GTZA 4MY4A 2W5TA 2ANHA 3M8ZA 3BDHA 1SHNA 3MK2A 3WAWA 2G9YA 4CXSA 1KH4A 4ZGAA 3UN5A 3BDFA 2GA3A 3SZZA 1KHNA 4MHXA 3NKRA 3NKNA 4LR2A 4CXUA 4ZG6A 1AJCA 1O98A 1URAA 4CYSA 3UN3A 2W5RA 2GLQA 3M7VA 5INHA 4LREA 5GOVA 4LRCA 2MVTA 1KH5A 5L0BA 3IGZB 1HQAA 4QAXA 4LRFA 3SZYA 5DLWA 3TWZA 1ALKA 3DYCA 3T01A 2W5WA 5DLVA 5K4PA 5DLTA 4LR9A 4LQYA 1KHKA 4TN0A 3CMRA 2VQRA 1N2LA 4LR7A 5L0KA 1HJKA 2W5XA 4UOPA 3IDDA 1O99A 3NVLA 1E3CP 3MK1A 3MK0A 4UPKA 3OT9A 4NWXA 5GRRA 1P49A 1K7HA 3B5QA 1N2KA 1AJAA 2W8DA 1EW9A 2M35A 3WAXA 2GSOA 2IFYA 1E2SP 3NKOA 4UPLA 3KD8A 3NKPA 5C66A 5KXAA 2W5SA 1ZEFA 1KHJA 1ZEBA 5EGEA 3E2DA 2GSNA 2W5QA 3M8YA 4ZG9A 5TJ3A 2W5VA 4MIVA 3WAVA 1ALJA 1B8JA 5L0EA 1EJJA 1KH9A 2W8SA 1EW8A 1URBA 1ELZA 1Y6VA 3TX0A 4NWJA 3M8WA 4GTWA 4UORA 4KJDA 2XR9A 4CYRA 3DPCA 5EGHA 3IGYB 1KH7A 2X98A 1EW2A 1ANJA 4GTYA 4LRDA 4UPHA 3UO0A 1ZEDA 4ZG7A 1ED9A 1AJDA 4FDIA 1ANIA 4KJGA 3WAYA 1ELXA 2ZKTA 2MUNA 4UPIA 2IUCA 5LRNA 3BDGB 1ED8A 2IUCB 3UNYA 3LXQA 4FDJA 5AJ9A 4LR8A 3TG0A 1HDHA 1E33P 3ED4A 5IJQA 4LRAA 1ALHA 3Q3QA 3NKQA 3UN2A 5HRTA 1EQJA 4N7TA 3NKMA 4KAVA 1ELYA 5LQQA 2GSUA 4KAYA 2XRGA 1ALIA 5LIAA 2QZUA 2RH6A 1KHLA 3WBHA 5IJSA 2D1GA 5LRMA 1Y7AA 1E1ZP 3A52A 1SHQA 1FSUA 1EI6A 4KM4A 4LRBA 2MZ4A 3T02A 4YR1A 3T00A 4CXKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AUK A;  4B56 A;  1AJB A;  3BDG A;  4GTX A;  4UOO A;  4GTZ A;  4MY4 A;  2W5T A;  2ANH A;  3M8Z A;  3BDH A;  1SHN A;  3MK2 A;  3WAW A;  2G9Y A;  4CXS A;  1KH4 A;  4ZGA A;  3UN5 A;  3BDF A;  2GA3 A;  3SZZ A;  1KHN A;  4MHX A;  3NKR A;  3NKN A;  4LR2 A;  4CXU A;  4ZG6 A;  1AJC A;  1O98 A;  1URA A;  4CYS A;  3UN3 A;  2W5R A;  2GLQ A;  3M7V A;  5INH A;  4LRE A;  5GOV A;  4LRC A;  1KH5 A;  5L0B A;  3IGZ B;  1HQA A;  4QAX A;  4LRF A;  3SZY A;  5DLW A;  3TWZ A;  1ALK A;  3DYC A;  3T01 A;  2W5W A;  5DLV A;  5K4P A;  5DLT A;  4LR9 A;  4LQY A;  1KHK A;  4TN0 A;  3CMR A;  2VQR A;  1N2L A;  4LR7 A;  5L0K A;  1HJK A;  2W5X A;  4UOP A;  3IDD A;  1O99 A;  3NVL A;  1E3C P;  3MK1 A;  3MK0 A;  4UPK A;  3OT9 A;  4NWX A;  5GRR A;  1P49 A;  1K7H A;  3B5Q A;  1N2K A;  1AJA A;  2W8D A;  1EW9 A;  3WAX A;  2GSO A;  2IFY A;  1E2S P;  3NKO A;  4UPL A;  3KD8 A;  3NKP A;  5C66 A;  5KXA A;  2W5S A;  1ZEF A;  1KHJ A;  1ZEB A;  5EGE A;  3E2D A;  2GSN A;  2W5Q A;  3M8Y A;  4ZG9 A;  5TJ3 A;  2W5V A;  4MIV A;  3WAV A;  1ALJ A;  1B8J A;  5L0E A;  1EJJ A;  1KH9 A;  2W8S A;  1EW8 A;  1URB A;  1ELZ A;  1Y6V A;  3TX0 A;  4NWJ A;  3M8W A;  4GTW A;  4UOR A;  4KJD A;  2XR9 A;  4CYR A;  3DPC A;  5EGH A;  3IGY B;  1KH7 A;  2X98 A;  1EW2 A;  1ANJ A;  4GTY A;  4LRD A;  4UPH A;  3UO0 A;  1ZED A;  4ZG7 A;  1ED9 A;  1AJD A;  4FDI A;  1ANI A;  4KJG A;  3WAY A;  1ELX A;  2ZKT A;  4UPI A;  2IUC A;  5LRN A;  3BDG B;  1ED8 A;  2IUC B;  3UNY A;  3LXQ A;  4FDJ A;  5AJ9 A;  4LR8 A;  3TG0 A;  1HDH A;  1E33 P;  3ED4 A;  5IJQ A;  4LRA A;  1ALH A;  3Q3Q A;  3NKQ A;  3UN2 A;  5HRT A;  1EQJ A;  4N7T A;  3NKM A;  4KAV A;  1ELY A;  5LQQ A;  2GSU A;  4KAY A;  2XRG A;  1ALI A;  5LIA A;  2QZU A;  2RH6 A;  1KHL A;  3WBH A;  5IJS A;  2D1G A;  5LRM A;  1Y7A A;  1E1Z P;  3A52 A;  1SHQ A;  1FSU A;  1EI6 A;  4KM4 A;  4LRB A;  3T02 A;  4YR1 A;  3T00 A;  4CXK A; 
#chains in the Genus database with same CATH topology
 1AUK A;  2F5E A;  4B56 A;  1AJB A;  3BDG A;  4GTX A;  4UOO A;  4GTZ A;  1G3Y A;  2W5T A;  2ANH A;  4MY4 A;  3M8Z A;  3BDH A;  1SHN A;  3MK2 A;  3WAW A;  3JAM R;  2G9Y A;  4CXS A;  1P92 A;  1KH4 A;  4ZGA A;  3UN5 A;  3BDF A;  2TDX A;  2GA3 A;  3SZZ A;  1KHN A;  4MHX A;  3NKR A;  3NKN A;  2F5D A;  4LR2 A;  4CXU A;  1G3W A;  4ZG6 A;  1AJC A;  1O98 A;  1URA A;  4CYS A;  3UN3 A;  2W5R A;  2GLQ A;  3M7V A;  2EV6 A;  5INH A;  4LRE A;  5GOV A;  1G3S A;  2MVT A;  1KH5 A;  4LRC A;  3IGZ B;  5L0B A;  1HQA A;  4QAX A;  4LRF A;  3SZY A;  1U8R A;  5A2Q R;  5DLW A;  3TWZ A;  1ALK A;  3DYC A;  3T01 A;  2W5W A;  5DLV A;  2F5C A;  5DLT A;  4LR9 A;  4LQY A;  5K4P A;  1BI2 A;  1KHK A;  4TN0 A;  3CMR A;  2VQR A;  1B1B A;  1N2L A;  4LR7 A;  5L0K A;  1HJK A;  1ON2 A;  2W5X A;  4UOP A;  3IDD A;  1XCV A;  1O99 A;  3NVL A;  1BI0 A;  1DDN A;  1E3C P;  3MK1 A;  2ISZ A;  3MK0 A;  1FWZ A;  4UPK A;  3OT9 A;  4NWX A;  5GRR A;  1P49 A;  1K7H A;  3J7A W;  3B5Q A;  4HV6 A;  1N2K A;  1AJA A;  4HV5 A;  5FLX R;  2W8D A;  4O6J A;  1EW9 A;  2M35 A;  3WAX A;  2F5F A;  2GSO A;  2IFY A;  1E2S P;  3NKO A;  4UPL A;  3J80 R;  3KD8 A;  3NKP A;  5C66 A;  5KXA A;  2QQ9 A;  2W5S A;  1KHJ A;  1ZEF A;  1ZEB A;  2QQA A;  5EGE A;  3J81 R;  3E2D A;  1C0W A;  2GSN A;  2DTR A;  2W5Q A;  3M8Y A;  4ZG9 A;  5TJ3 A;  3R61 A;  1FX7 A;  2W5V A;  4MIV A;  1B8J A;  3WAV A;  1ALJ A;  5L0E A;  1EJJ A;  1G3T A;  1BI1 A;  4HX7 A;  1KH9 A;  2W8S A;  1EW8 A;  1URB A;  1ELZ A;  1Y6V A;  3TX0 A;  4NWJ A;  2HYG D;  3M8W A;  4GTW A;  4KJD A;  2XR9 A;  4UOR A;  4CYR A;  3DPC A;  5EGH A;  3IGY B;  2EV5 A;  2X98 A;  1EW2 A;  1ANJ A;  1KH7 A;  4GTY A;  4LRD A;  4UPH A;  4HX4 A;  1ZED A;  3UO0 A;  4ZG7 A;  1ED9 A;  4HX8 A;  1AJD A;  4FDI A;  1F5T A;  1ANI A;  4KJG A;  3WAY A;  1ELX A;  2ZKT A;  2MUN A;  4UPI A;  2IUC A;  1DPR A;  5LRN A;  3BDG B;  1ED8 A;  2IUC B;  3UNY A;  3LXQ A;  4FDJ A;  5AJ9 A;  2QQB A;  4LR8 A;  1ON1 A;  1HDH A;  1E33 P;  3ED4 A;  5IJQ A;  3TG0 A;  4LRA A;  1ALH A;  3Q3Q A;  3NKQ A;  3UN2 A;  5HRT A;  1EQJ A;  4O5V A;  4N7T A;  3NKM A;  4KAV A;  1ELY A;  2HYF A;  5LQQ A;  2GSU A;  2P0T A;  3R60 A;  2H09 A;  4KAY A;  2XRG A;  1ALI A;  1RQ6 A;  5LIA A;  2QZU A;  2RH6 A;  1KHL A;  3WBH A;  5IJS A;  2D1G A;  5IT9 R;  5LRM A;  1Y7A A;  1E1Z P;  3A52 A;  3GLX A;  1FSU A;  1SHQ A;  1EI6 A;  4KM4 A;  4LRB A;  2MZ4 A;  3T02 A;  4YR1 A;  3T00 A;  4CXK A;  2EV0 A;  1BI3 A; 
#chains in the Genus database with same CATH homology
 1AUK A;  4B56 A;  1AJB A;  3BDG A;  4GTX A;  4UOO A;  4GTZ A;  4MY4 A;  2W5T A;  2ANH A;  3M8Z A;  3BDH A;  1SHN A;  3MK2 A;  3WAW A;  2G9Y A;  4CXS A;  1KH4 A;  4ZGA A;  3UN5 A;  3BDF A;  2GA3 A;  3SZZ A;  1KHN A;  4MHX A;  3NKR A;  3NKN A;  4LR2 A;  4CXU A;  4ZG6 A;  1AJC A;  1O98 A;  1URA A;  4CYS A;  3UN3 A;  2W5R A;  2GLQ A;  3M7V A;  5INH A;  4LRE A;  5GOV A;  4LRC A;  2MVT A;  1KH5 A;  5L0B A;  3IGZ B;  1HQA A;  4QAX A;  4LRF A;  3SZY A;  5DLW A;  3TWZ A;  1ALK A;  3DYC A;  3T01 A;  2W5W A;  5DLV A;  5K4P A;  5DLT A;  4LR9 A;  4LQY A;  1KHK A;  4TN0 A;  3CMR A;  2VQR A;  1N2L A;  4LR7 A;  5L0K A;  1HJK A;  2W5X A;  4UOP A;  3IDD A;  1O99 A;  3NVL A;  1E3C P;  3MK1 A;  3MK0 A;  4UPK A;  3OT9 A;  4NWX A;  5GRR A;  1P49 A;  1K7H A;  3B5Q A;  1N2K A;  1AJA A;  2W8D A;  1EW9 A;  2M35 A;  3WAX A;  2GSO A;  2IFY A;  1E2S P;  3NKO A;  4UPL A;  3KD8 A;  3NKP A;  5C66 A;  5KXA A;  2W5S A;  1ZEF A;  1KHJ A;  1ZEB A;  5EGE A;  3E2D A;  2GSN A;  2W5Q A;  3M8Y A;  4ZG9 A;  5TJ3 A;  2W5V A;  4MIV A;  3WAV A;  1ALJ A;  1B8J A;  5L0E A;  1EJJ A;  1KH9 A;  2W8S A;  1EW8 A;  1URB A;  1ELZ A;  1Y6V A;  3TX0 A;  4NWJ A;  3M8W A;  4GTW A;  4UOR A;  4KJD A;  2XR9 A;  4CYR A;  3DPC A;  5EGH A;  3IGY B;  1KH7 A;  2X98 A;  1EW2 A;  1ANJ A;  4GTY A;  4LRD A;  4UPH A;  3UO0 A;  1ZED A;  4ZG7 A;  1ED9 A;  1AJD A;  4FDI A;  1ANI A;  4KJG A;  3WAY A;  1ELX A;  2ZKT A;  2MUN A;  4UPI A;  2IUC A;  5LRN A;  3BDG B;  1ED8 A;  2IUC B;  3UNY A;  3LXQ A;  4FDJ A;  5AJ9 A;  4LR8 A;  3TG0 A;  1HDH A;  1E33 P;  3ED4 A;  5IJQ A;  4LRA A;  1ALH A;  3Q3Q A;  3NKQ A;  3UN2 A;  5HRT A;  1EQJ A;  4N7T A;  3NKM A;  4KAV A;  1ELY A;  5LQQ A;  2GSU A;  4KAY A;  2XRG A;  1ALI A;  5LIA A;  2QZU A;  2RH6 A;  1KHL A;  3WBH A;  5IJS A;  2D1G A;  5LRM A;  1Y7A A;  1E1Z P;  3A52 A;  1SHQ A;  1FSU A;  1EI6 A;  4KM4 A;  4LRB A;  2MZ4 A;  3T02 A;  4YR1 A;  3T00 A;  4CXK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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