2X98A

H.salinarum alkaline phosphatase
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
Knots found
sequence length
430
structure length
430
Chain Sequence
ASPAANAIAYIVDGMGQTQISAARYLNAYKTAPERFPLNVSPAETPTGFDAFSSRGSMTTFPDDPYETTTDSAAAATAFASGVKTYNGAIGGVQTSGGGFQRVDTVLERASAQGYATGLITTTEATHATPAAFAAHVEDRGNQTEIARQYIEETQPDVILGGQRRDFEADASNGGTLVDAARDNGYTIAETAAELDAVDDPPVLGLFSQESHLDYYLDRKNDPENTQPNLDAMVDAGVDLLSSAGDPDKGFFLLVESGRVDHAGHANYPAQVAEQYEATQVAGQLVEYAETTAEPTFLVSTGDHECGGLTLGRDSPYEVEYDVLAAQKATTSRLRDLLAGVRSADELESIVAAHTGITALTDREVAKLRDAPGSISTILAERAGIAFTTDGHTGTDVPVFAHGPNAARFDAARDNTAVADALAAALGVSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALKALINE PHOSPHATASE
publication title Structural and Biochemical Characterization of a Halophilic Archaeal Alkaline Phosphatase.
pubmed doi rcsb
source organism Halobacterium salinarum
molecule tags Hydrolase
total genus 149
structure length 430
sequence length 430
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2010-03-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.60.40 Mainly Alpha Orthogonal Bundle Diphtheria Toxin Repressor; domain 2 Diphtheria Toxin Repressor; domain 2 2x98A02
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2x98A01
4UOOA 3T02A 3A52A 3BDGB 1B8JA 2X98A 1EW9A 3NKRA 3BDFA 4GTXA 1O99A 1Y6VA 5EGHA 2W8DA 1ALIA 4CXKA 4KJGA 4CYRA 4ZG7A 4GTWA 2IUCA 4FDJA 3MK1A 2ZKTA 4TN0A 1URAA 1SHQA 4YR1A 3ED4A 3UN2A 1EQJA 5TJ3A 1ALKA 1K7HA 4GTZA 4UORA 1KHKA 2ANHA 5DLWA 1ELXA 3MK0A 2GSNA 1HJKA 2XRGA 3UN3A 3DPCA 3M7VA 1EW2A 5GRRA 3WAVA 2W5RA 3WAXA 5LRNA 2GLQA 2RH6A 4ZGAA 5IJSA 1ELYA 2W5TA 1KH5A 3T00A 4CXSA 1E3CP 3TWZA 3BDHA 2VQRA 4UPHA 5GOVA 4KAYA 3E2DA 1ZEFA 3NKQA 4UOPA 5L0BA 4LR2A 1O98A 4LR7A 1KH7A 1AJCA 1ELZA 5EGEA 3WBHA 4ZG9A 5DLVA 1ED9A 4NWXA 4LREA 1ED8A 1URBA 3KD8A 3OT9A 4LRBA 4FDIA 5HRTA 3Q3QA 3B5QA 4B56A 2W5XA 4UPKA 1E33P 1KHJA 5INHA 3WAWA 2D1GA 2W5WA 1ALJA 5DLTA 1ANIA 3MK2A 1E2SP 1EJJA 3NKNA 4QAXA 4LR9A 1HDHA 4CXUA 3UN5A 1Y7AA 3NKOA 1KH9A 1AJAA 5L0EA 2GA3A 1ZEBA 4LRFA 3UNYA 4NWJA 4MY4A 4UPLA 3M8YA 4GTYA 5LRMA 4ZG6A 4LQYA 1ZEDA 2GSOA 3NKPA 5IJQA 4CYSA 3TX0A 5C66A 2W5SA 2IUCB 1E1ZP 2IFYA 5K4PA 1FSUA 3BDGA 3LXQA 5L0KA 3IDDA 1N2KA 3M8ZA 2GSUA 1AJDA 1EW8A 1KHNA 3SZYA 2G9YA 4MHXA 3WAYA 1HQAA 2XR9A 3NVLA 4LRDA 4N7TA 1P49A 4LR8A 1KHLA 1ALHA 4KM4A 1SHNA 3SZZA 4LRCA 3UO0A 2W5VA 3NKMA 4LRAA 1AUKA 3T01A 1ANJA 3IGZB 5AJ9A 5LQQA 1EI6A 4KJDA 5KXAA 4UPIA 1AJBA 1N2LA 3DYCA 3CMRA 3M8WA 2W5QA 3TG0A 1KH4A 4KAVA 5LIAA 3IGYB 2QZUA 4MIVA 2W8SA
chains in the Genus database with same CATH superfamily
4UOOA 3T02A 3A52A 4HV6A 3BDGB 1B8JA 2X98A 4HX4A 1EW9A 3BDFA 3NKRA 4GTXA 1O99A 1Y6VA 5EGHA 2W8DA 1ALIA 2MVTA 4CXKA 4KJGA 2W8SA 2MUNA 5A2QR 1RQ6A 4CYRA 4ZG7A 4GTWA 2IUCA 4FDJA 3MK1A 2ZKTA 4TN0A 1BI2A 1URAA 1SHQA 3GLXA 4YR1A 3ED4A 5FLXR 3UN2A 1EQJA 5TJ3A 1DDNA 2HYGD 1ALKA 1K7HA 4GTZA 1KHKA 4O6JA 2ANHA 4UORA 5DLWA 1ELXA 3MK0A 2GSNA 1HJKA 2XRGA 3UN3A 3DPCA 1ON2A 5IT9R 3M7VA 2QZUA 1EW2A 5GRRA 3WAVA 2W5RA 3WAXA 1FWZA 5LRNA 2GLQA 2RH6A 1B1BA 1FX7A 2EV5A 1G3SA 1XCVA 4ZGAA 5IJSA 1ELYA 2W5TA 2QQBA 1KH5A 3T00A 4CXSA 1E3CP 3TWZA 3BDHA 2VQRA 4UPHA 4HX8A 4KAYA 3E2DA 5GOVA 1ZEFA 3NKQA 4UOPA 5L0BA 1G3TA 4LR2A 1O98A 4LR7A 1F5TA 1KH7A 1AJCA 3JAMR 2F5DA 2F5FA 1ELZA 5EGEA 3WBHA 4ZG9A 5DLVA 1ED9A 4NWXA 4LREA 1ED8A 1URBA 3KD8A 3OT9A 4LRBA 1DPRA 4FDIA 2EV0A 5HRTA 3Q3QA 2HYFA 1U8RA 3B5QA 4B56A 4HV5A 2W5XA 1G3WA 4UPKA 1E33P 1KHJA 5INHA 3WAWA 2D1GA 2W5WA 3R60A 5DLTA 1ANIA 1ALJA 3MK2A 1E2SP 1EJJA 3NKNA 4QAXA 4LR9A 3J81R 1HDHA 4CXUA 3UN5A 1Y7AA 2QQAA 3NKOA 1KH9A 1AJAA 5L0EA 2GA3A 1ZEBA 4LRFA 3UNYA 1ON1A 2ISZA 4NWJA 2TDXA 4MY4A 4UPLA 3M8YA 4GTYA 1G3YA 1BI1A 5LRMA 3J80R 4ZG6A 4LQYA 1ZEDA 2GSOA 3NKPA 5IJQA 4CYSA 3TX0A 5C66A 2W5SA 2IUCB 1E1ZP 2IFYA 5K4PA 1FSUA 3BDGA 3LXQA 5L0KA 3IDDA 1BI3A 1N2KA 3M8ZA 2GSUA 1AJDA 1EW8A 1KHNA 3SZYA 1BI0A 2G9YA 4MHXA 3WAYA 1HQAA 4HX7A 2H09A 2XR9A 3NVLA 4LRDA 4N7TA 1P49A 4LR8A 1KHLA 1ALHA 4KM4A 1SHNA 3SZZA 4LRCA 3UO0A 2M35A 2W5VA 2P0TA 3NKMA 1AUKA 4LRAA 3T01A 1ANJA 2QQ9A 3IGZB 5AJ9A 5LQQA 3R61A 1EI6A 4KJDA 5KXAA 4UPIA 1AJBA 1N2LA 3DYCA 3CMRA 1C0WA 3M8WA 2MZ4A 2W5QA 3TG0A 1KH4A 3J7AW 4O5VA 2EV6A 4KAVA 5LIAA 2F5CA 3IGYB 1P92A 2F5EA 4MIVA 2DTRA
chains in the Genus database with same CATH topology
4UOOA 3T02A 3A52A 3BDGB 1B8JA 2X98A 1EW9A 3NKRA 3BDFA 4GTXA 1O99A 1Y6VA 5EGHA 2W8DA 1ALIA 2MVTA 4CXKA 4KJGA 2MUNA 4CYRA 4ZG7A 4GTWA 2IUCA 4FDJA 3MK1A 2ZKTA 4TN0A 1URAA 1SHQA 4YR1A 3ED4A 3UN2A 1EQJA 5TJ3A 1ALKA 1K7HA 4GTZA 4UORA 1KHKA 2ANHA 5DLWA 1ELXA 3MK0A 2GSNA 1HJKA 2XRGA 3UN3A 3DPCA 3M7VA 1EW2A 5GRRA 3WAVA 2W5RA 3WAXA 5LRNA 2GLQA 2RH6A 4ZGAA 5IJSA 1ELYA 2W5TA 1KH5A 3T00A 4CXSA 1E3CP 3TWZA 3BDHA 2VQRA 4UPHA 5GOVA 4KAYA 3E2DA 1ZEFA 3NKQA 4UOPA 5L0BA 4LR2A 1O98A 4LR7A 1KH7A 1AJCA 1ELZA 5EGEA 3WBHA 4ZG9A 5DLVA 1ED9A 4NWXA 4LREA 1ED8A 1URBA 3KD8A 3OT9A 4LRBA 4FDIA 5HRTA 3Q3QA 3B5QA 4B56A 2W5XA 4UPKA 1E33P 1KHJA 5INHA 3WAWA 2D1GA 2W5WA 1ALJA 5DLTA 1ANIA 3MK2A 1E2SP 1EJJA 3NKNA 4QAXA 4LR9A 1HDHA 4CXUA 3UN5A 1Y7AA 3NKOA 1KH9A 1AJAA 5L0EA 2GA3A 1ZEBA 4LRFA 3UNYA 4NWJA 4MY4A 4UPLA 3M8YA 4GTYA 5LRMA 4ZG6A 4LQYA 1ZEDA 2GSOA 3NKPA 5IJQA 4CYSA 3TX0A 5C66A 2W5SA 2IUCB 1E1ZP 2IFYA 5K4PA 1FSUA 3BDGA 3LXQA 5L0KA 3IDDA 1N2KA 3M8ZA 2GSUA 1AJDA 1EW8A 1KHNA 3SZYA 2G9YA 4MHXA 3WAYA 1HQAA 2XR9A 3NVLA 4LRDA 4N7TA 1P49A 4LR8A 1KHLA 1ALHA 4KM4A 1SHNA 3SZZA 4LRCA 3UO0A 2M35A 2W5VA 3NKMA 4LRAA 1AUKA 3T01A 1ANJA 3IGZB 5AJ9A 5LQQA 1EI6A 4KJDA 5KXAA 4UPIA 1AJBA 1N2LA 3DYCA 3CMRA 3M8WA 2MZ4A 2W5QA 3TG0A 1KH4A 4KAVA 5LIAA 3IGYB 2QZUA 4MIVA 2W8SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UOO A;  3T02 A;  3A52 A;  3BDG B;  1B8J A;  2X98 A;  1EW9 A;  3NKR A;  3BDF A;  4GTX A;  1O99 A;  1Y6V A;  5EGH A;  2W8D A;  1ALI A;  4CXK A;  4KJG A;  4CYR A;  4ZG7 A;  4GTW A;  2IUC A;  4FDJ A;  3MK1 A;  2ZKT A;  4TN0 A;  1URA A;  1SHQ A;  4YR1 A;  3ED4 A;  3UN2 A;  1EQJ A;  5TJ3 A;  1ALK A;  1K7H A;  4GTZ A;  4UOR A;  1KHK A;  2ANH A;  5DLW A;  1ELX A;  3MK0 A;  2GSN A;  1HJK A;  2XRG A;  3UN3 A;  3DPC A;  3M7V A;  1EW2 A;  5GRR A;  3WAV A;  2W5R A;  3WAX A;  5LRN A;  2GLQ A;  2RH6 A;  4ZGA A;  5IJS A;  1ELY A;  2W5T A;  1KH5 A;  3T00 A;  4CXS A;  1E3C P;  3TWZ A;  3BDH A;  2VQR A;  4UPH A;  5GOV A;  4KAY A;  3E2D A;  1ZEF A;  3NKQ A;  4UOP A;  5L0B A;  4LR2 A;  1O98 A;  4LR7 A;  1KH7 A;  1AJC A;  1ELZ A;  5EGE A;  3WBH A;  4ZG9 A;  5DLV A;  1ED9 A;  4NWX A;  4LRE A;  1ED8 A;  1URB A;  3KD8 A;  3OT9 A;  4LRB A;  4FDI A;  5HRT A;  3Q3Q A;  3B5Q A;  4B56 A;  2W5X A;  4UPK A;  1E33 P;  1KHJ A;  5INH A;  3WAW A;  2D1G A;  2W5W A;  1ALJ A;  5DLT A;  1ANI A;  3MK2 A;  1E2S P;  1EJJ A;  3NKN A;  4QAX A;  4LR9 A;  1HDH A;  4CXU A;  3UN5 A;  1Y7A A;  3NKO A;  1KH9 A;  1AJA A;  5L0E A;  2GA3 A;  1ZEB A;  4LRF A;  3UNY A;  4NWJ A;  4MY4 A;  4UPL A;  3M8Y A;  4GTY A;  5LRM A;  4ZG6 A;  4LQY A;  1ZED A;  2GSO A;  3NKP A;  5IJQ A;  4CYS A;  3TX0 A;  5C66 A;  2W5S A;  2IUC B;  1E1Z P;  2IFY A;  5K4P A;  1FSU A;  3BDG A;  3LXQ A;  5L0K A;  3IDD A;  1N2K A;  3M8Z A;  2GSU A;  1AJD A;  1EW8 A;  1KHN A;  3SZY A;  2G9Y A;  4MHX A;  3WAY A;  1HQA A;  2XR9 A;  3NVL A;  4LRD A;  4N7T A;  1P49 A;  4LR8 A;  1KHL A;  1ALH A;  4KM4 A;  1SHN A;  3SZZ A;  4LRC A;  3UO0 A;  2W5V A;  3NKM A;  4LRA A;  1AUK A;  3T01 A;  1ANJ A;  3IGZ B;  5AJ9 A;  5LQQ A;  1EI6 A;  4KJD A;  5KXA A;  4UPI A;  1AJB A;  1N2L A;  3DYC A;  3CMR A;  3M8W A;  2W5Q A;  3TG0 A;  1KH4 A;  4KAV A;  5LIA A;  3IGY B;  2QZU A;  4MIV A;  2W8S A; 
#chains in the Genus database with same CATH topology
 4UOO A;  3T02 A;  3A52 A;  4HV6 A;  3BDG B;  1B8J A;  2X98 A;  4HX4 A;  1EW9 A;  3BDF A;  3NKR A;  4GTX A;  1O99 A;  1Y6V A;  5EGH A;  2W8D A;  1ALI A;  2MVT A;  4CXK A;  4KJG A;  2W8S A;  2MUN A;  5A2Q R;  1RQ6 A;  4CYR A;  4ZG7 A;  4GTW A;  2IUC A;  4FDJ A;  3MK1 A;  2ZKT A;  4TN0 A;  1BI2 A;  1URA A;  1SHQ A;  3GLX A;  4YR1 A;  3ED4 A;  5FLX R;  3UN2 A;  1EQJ A;  5TJ3 A;  1DDN A;  2HYG D;  1ALK A;  1K7H A;  4GTZ A;  1KHK A;  4O6J A;  2ANH A;  4UOR A;  5DLW A;  1ELX A;  3MK0 A;  2GSN A;  1HJK A;  2XRG A;  3UN3 A;  3DPC A;  1ON2 A;  5IT9 R;  3M7V A;  2QZU A;  1EW2 A;  5GRR A;  3WAV A;  2W5R A;  3WAX A;  1FWZ A;  5LRN A;  2GLQ A;  2RH6 A;  1B1B A;  1FX7 A;  2EV5 A;  1G3S A;  1XCV A;  4ZGA A;  5IJS A;  1ELY A;  2W5T A;  2QQB A;  1KH5 A;  3T00 A;  4CXS A;  1E3C P;  3TWZ A;  3BDH A;  2VQR A;  4UPH A;  4HX8 A;  4KAY A;  3E2D A;  5GOV A;  1ZEF A;  3NKQ A;  4UOP A;  5L0B A;  1G3T A;  4LR2 A;  1O98 A;  4LR7 A;  1F5T A;  1KH7 A;  1AJC A;  3JAM R;  2F5D A;  2F5F A;  1ELZ A;  5EGE A;  3WBH A;  4ZG9 A;  5DLV A;  1ED9 A;  4NWX A;  4LRE A;  1ED8 A;  1URB A;  3KD8 A;  3OT9 A;  4LRB A;  1DPR A;  4FDI A;  2EV0 A;  5HRT A;  3Q3Q A;  2HYF A;  1U8R A;  3B5Q A;  4B56 A;  4HV5 A;  2W5X A;  1G3W A;  4UPK A;  1E33 P;  1KHJ A;  5INH A;  3WAW A;  2D1G A;  2W5W A;  3R60 A;  5DLT A;  1ANI A;  1ALJ A;  3MK2 A;  1E2S P;  1EJJ A;  3NKN A;  4QAX A;  4LR9 A;  3J81 R;  1HDH A;  4CXU A;  3UN5 A;  1Y7A A;  2QQA A;  3NKO A;  1KH9 A;  1AJA A;  5L0E A;  2GA3 A;  1ZEB A;  4LRF A;  3UNY A;  1ON1 A;  2ISZ A;  4NWJ A;  2TDX A;  4MY4 A;  4UPL A;  3M8Y A;  4GTY A;  1G3Y A;  1BI1 A;  5LRM A;  3J80 R;  4ZG6 A;  4LQY A;  1ZED A;  2GSO A;  3NKP A;  5IJQ A;  4CYS A;  3TX0 A;  5C66 A;  2W5S A;  2IUC B;  1E1Z P;  2IFY A;  5K4P A;  1FSU A;  3BDG A;  3LXQ A;  5L0K A;  3IDD A;  1BI3 A;  1N2K A;  3M8Z A;  2GSU A;  1AJD A;  1EW8 A;  1KHN A;  3SZY A;  1BI0 A;  2G9Y A;  4MHX A;  3WAY A;  1HQA A;  4HX7 A;  2H09 A;  2XR9 A;  3NVL A;  4LRD A;  4N7T A;  1P49 A;  4LR8 A;  1KHL A;  1ALH A;  4KM4 A;  1SHN A;  3SZZ A;  4LRC A;  3UO0 A;  2M35 A;  2W5V A;  2P0T A;  3NKM A;  1AUK A;  4LRA A;  3T01 A;  1ANJ A;  2QQ9 A;  3IGZ B;  5AJ9 A;  5LQQ A;  3R61 A;  1EI6 A;  4KJD A;  5KXA A;  4UPI A;  1AJB A;  1N2L A;  3DYC A;  3CMR A;  1C0W A;  3M8W A;  2MZ4 A;  2W5Q A;  3TG0 A;  1KH4 A;  3J7A W;  4O5V A;  2EV6 A;  4KAV A;  5LIA A;  2F5C A;  3IGY B;  1P92 A;  2F5E A;  4MIV A;  2DTR A; 
#chains in the Genus database with same CATH homology
 4UOO A;  3T02 A;  3A52 A;  3BDG B;  1B8J A;  2X98 A;  1EW9 A;  3NKR A;  3BDF A;  4GTX A;  1O99 A;  1Y6V A;  5EGH A;  2W8D A;  1ALI A;  2MVT A;  4CXK A;  4KJG A;  2MUN A;  4CYR A;  4ZG7 A;  4GTW A;  2IUC A;  4FDJ A;  3MK1 A;  2ZKT A;  4TN0 A;  1URA A;  1SHQ A;  4YR1 A;  3ED4 A;  3UN2 A;  1EQJ A;  5TJ3 A;  1ALK A;  1K7H A;  4GTZ A;  4UOR A;  1KHK A;  2ANH A;  5DLW A;  1ELX A;  3MK0 A;  2GSN A;  1HJK A;  2XRG A;  3UN3 A;  3DPC A;  3M7V A;  1EW2 A;  5GRR A;  3WAV A;  2W5R A;  3WAX A;  5LRN A;  2GLQ A;  2RH6 A;  4ZGA A;  5IJS A;  1ELY A;  2W5T A;  1KH5 A;  3T00 A;  4CXS A;  1E3C P;  3TWZ A;  3BDH A;  2VQR A;  4UPH A;  5GOV A;  4KAY A;  3E2D A;  1ZEF A;  3NKQ A;  4UOP A;  5L0B A;  4LR2 A;  1O98 A;  4LR7 A;  1KH7 A;  1AJC A;  1ELZ A;  5EGE A;  3WBH A;  4ZG9 A;  5DLV A;  1ED9 A;  4NWX A;  4LRE A;  1ED8 A;  1URB A;  3KD8 A;  3OT9 A;  4LRB A;  4FDI A;  5HRT A;  3Q3Q A;  3B5Q A;  4B56 A;  2W5X A;  4UPK A;  1E33 P;  1KHJ A;  5INH A;  3WAW A;  2D1G A;  2W5W A;  1ALJ A;  5DLT A;  1ANI A;  3MK2 A;  1E2S P;  1EJJ A;  3NKN A;  4QAX A;  4LR9 A;  1HDH A;  4CXU A;  3UN5 A;  1Y7A A;  3NKO A;  1KH9 A;  1AJA A;  5L0E A;  2GA3 A;  1ZEB A;  4LRF A;  3UNY A;  4NWJ A;  4MY4 A;  4UPL A;  3M8Y A;  4GTY A;  5LRM A;  4ZG6 A;  4LQY A;  1ZED A;  2GSO A;  3NKP A;  5IJQ A;  4CYS A;  3TX0 A;  5C66 A;  2W5S A;  2IUC B;  1E1Z P;  2IFY A;  5K4P A;  1FSU A;  3BDG A;  3LXQ A;  5L0K A;  3IDD A;  1N2K A;  3M8Z A;  2GSU A;  1AJD A;  1EW8 A;  1KHN A;  3SZY A;  2G9Y A;  4MHX A;  3WAY A;  1HQA A;  2XR9 A;  3NVL A;  4LRD A;  4N7T A;  1P49 A;  4LR8 A;  1KHL A;  1ALH A;  4KM4 A;  1SHN A;  3SZZ A;  4LRC A;  3UO0 A;  2M35 A;  2W5V A;  3NKM A;  4LRA A;  1AUK A;  3T01 A;  1ANJ A;  3IGZ B;  5AJ9 A;  5LQQ A;  1EI6 A;  4KJD A;  5KXA A;  4UPI A;  1AJB A;  1N2L A;  3DYC A;  3CMR A;  3M8W A;  2MZ4 A;  2W5Q A;  3TG0 A;  1KH4 A;  4KAV A;  5LIA A;  3IGY B;  2QZU A;  4MIV A;  2W8S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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