3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
Knots found
sequence length
449
structure length
449
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
total genus 147
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
4GTZA 3WBHA 3IGZB 2XR9A 1KH7A 4ZGAA 4UPKA 1ZEDA 3LXQA 2GSUA 4MY4A 2RH6A 5IJQA 1ALIA 3NKQA 1HDHA 3NKOA 1KHLA 4CXUA 2ZKTA 1URAA 4NWXA 1Y7AA 3M8WA 5GOVA 1URBA 1B8JA 4LRFA 2W5XA 4TN0A 4LR2A 4NWJA 1E2SP 3SZZA 1ELYA 1ALHA 1KH4A 1O98A 2W5WA 4YR1A 5L0BA 3IDDA 4CXKA 5L0EA 1ANIA 1ZEBA 4ZG7A 4LRAA 3BDHA 1ELXA 3NVLA 1N2LA 1E3CP 5LRNA 3WAWA 1ED8A 1AJAA 4ZG9A 3CMRA 3MK1A 4N7TA 1Y6VA 5LRMA 1HQAA 3NKRA 4KM4A 3BDGB 1KHJA 3SZYA 1AJDA 2IUCB 4GTXA 5EGHA 1E1ZP 4UOPA 2G9YA 2IFYA 1EW2A 3M7VA 5LIAA 3BDGA 3DPCA 4KJGA 2IUCA 5DLVA 1N2KA 1KHKA 4UPLA 5DLTA 2D1GA 1EI6A 2W5VA 2W5QA 4MIVA 5AJ9A 5INHA 3TWZA 5GRRA 3UNYA 4CXSA 3Q3QA 3UO0A 3T01A 3ED4A 4ZG6A 2GA3A 1SHQA 3MK2A 3T00A 1KH9A 1ALKA 4LR9A 4KAYA 3E2DA 3NKMA 4LRCA 4UPIA 4LRDA 4UOOA 1EW8A 2GSOA 3B5QA 4GTWA 5TJ3A 4KAVA 4GTYA 1ZEFA 1KH5A 1SHNA 5C66A 2W8DA 4LR8A 4MHXA 1O99A 1P49A 4LREA 3UN2A 4FDJA 3UN3A 3TG0A 4LQYA 3KD8A 2QZUA 3DYCA 4KJDA 3T02A 1AUKA 5L0KA 1E33P 5EGEA 2W5RA 1FSUA 3MK0A 5IJSA 3M8ZA 2ANHA 4FDIA 1HJKA 2W5TA 3A52A 4LRBA 1ALJA 1AJCA 2GLQA 1EJJA 2GSNA 4LR7A 3UN5A 1KHNA 2VQRA 3IGYB 4CYRA 3NKPA 4CYSA 3NKNA 5K4PA 1K7HA 1EQJA 5LQQA 3BDFA 5DLWA 2XRGA 4UORA 1AJBA 1ANJA 4QAXA 1ELZA 1EW9A 3WAYA 3OT9A 3TX0A 2W5SA 5HRTA 4UPHA 1ED9A 2X98A 4B56A 2W8SA 3M8YA 3WAVA 5KXAA 3WAXA
chains in the Genus database with same CATH superfamily
4GTZA 3WBHA 3IGZB 2XR9A 1KH7A 4ZGAA 4UPKA 1ZEDA 3LXQA 2GSUA 4MY4A 2RH6A 5IJQA 1ALIA 3NKQA 1HDHA 3NKOA 1KHLA 4CXUA 2ZKTA 1URAA 4NWXA 1Y7AA 3M8WA 5GOVA 1URBA 1B8JA 4LRFA 2W5XA 4TN0A 4LR2A 4NWJA 1E2SP 3SZZA 1ELYA 1ALHA 1KH4A 1O98A 2W5WA 4YR1A 5L0BA 3IDDA 4CXKA 5L0EA 1ANIA 1ZEBA 4ZG7A 4LRAA 3BDHA 1ELXA 3NVLA 1N2LA 1E3CP 5LRNA 3WAWA 1ED8A 1AJAA 4ZG9A 3CMRA 3MK1A 4N7TA 1Y6VA 5LRMA 1HQAA 3NKRA 4KM4A 3BDGB 1KHJA 3SZYA 1AJDA 2IUCB 4GTXA 5EGHA 1E1ZP 4UOPA 2G9YA 2IFYA 1EW2A 3M7VA 5LIAA 3BDGA 3DPCA 4KJGA 2IUCA 5DLVA 1N2KA 1KHKA 4UPLA 5DLTA 2D1GA 1EI6A 2W5VA 2W5QA 4MIVA 5AJ9A 5INHA 3TWZA 5GRRA 3UNYA 4CXSA 3Q3QA 3UO0A 3T01A 3ED4A 4ZG6A 2GA3A 1SHQA 3MK2A 3T00A 1KH9A 1ALKA 4LR9A 4KAYA 3E2DA 3NKMA 4LRCA 4UPIA 4LRDA 4UOOA 1EW8A 2GSOA 3B5QA 4GTWA 5TJ3A 4KAVA 4GTYA 1ZEFA 1KH5A 1SHNA 5C66A 2W8DA 4LR8A 4MHXA 1O99A 1P49A 4LREA 3UN2A 4FDJA 3UN3A 3TG0A 4LQYA 3KD8A 2QZUA 3DYCA 4KJDA 3T02A 1AUKA 5L0KA 1E33P 5EGEA 2W5RA 1FSUA 3MK0A 5IJSA 3M8ZA 2ANHA 4FDIA 1HJKA 2W5TA 3A52A 4LRBA 1ALJA 1AJCA 2GLQA 1EJJA 2GSNA 4LR7A 3UN5A 1KHNA 2VQRA 3IGYB 4CYRA 3NKPA 4CYSA 3NKNA 5K4PA 1K7HA 1EQJA 5LQQA 3BDFA 5DLWA 2XRGA 4UORA 1AJBA 1ANJA 4QAXA 1ELZA 1EW9A 3WAYA 3OT9A 3TX0A 2W5SA 5HRTA 4UPHA 1ED9A 2X98A 4B56A 2W8SA 3M8YA 3WAVA 5KXAA 3WAXA
chains in the Genus database with same CATH topology
4GTZA 3WBHA 3IGZB 2XR9A 1KH7A 4ZGAA 4UPKA 1ZEDA 3LXQA 2GSUA 4MY4A 2RH6A 5IJQA 1ALIA 3NKQA 1HDHA 3NKOA 1KHLA 4CXUA 2ZKTA 1URAA 4NWXA 1Y7AA 3M8WA 5GOVA 1URBA 1B8JA 4LRFA 2W5XA 4TN0A 4LR2A 4NWJA 1E2SP 3SZZA 1ELYA 1ALHA 1KH4A 1O98A 2W5WA 4YR1A 5L0BA 3IDDA 4CXKA 5L0EA 1ANIA 1ZEBA 4ZG7A 4LRAA 3BDHA 1ELXA 3NVLA 1N2LA 1E3CP 5LRNA 3WAWA 1ED8A 1AJAA 4ZG9A 3CMRA 3MK1A 4N7TA 1Y6VA 5LRMA 1HQAA 3NKRA 4KM4A 3BDGB 1KHJA 3SZYA 1AJDA 2IUCB 4GTXA 5EGHA 1E1ZP 4UOPA 2G9YA 2IFYA 1EW2A 3M7VA 5LIAA 3BDGA 3DPCA 4KJGA 2IUCA 5DLVA 1N2KA 1KHKA 4UPLA 5DLTA 2D1GA 1EI6A 2W5VA 2W5QA 4MIVA 5AJ9A 5INHA 3TWZA 5GRRA 3UNYA 4CXSA 3Q3QA 3UO0A 3T01A 3ED4A 4ZG6A 2GA3A 1SHQA 3MK2A 3T00A 1KH9A 1ALKA 4LR9A 4KAYA 3E2DA 3NKMA 4LRCA 4UPIA 4LRDA 4UOOA 1EW8A 2GSOA 3B5QA 4GTWA 5TJ3A 4KAVA 4GTYA 1ZEFA 1KH5A 1SHNA 5C66A 2W8DA 4LR8A 4MHXA 1O99A 1P49A 4LREA 3UN2A 4FDJA 3UN3A 3TG0A 4LQYA 3KD8A 2QZUA 3DYCA 4KJDA 3T02A 1AUKA 5L0KA 1E33P 5EGEA 2W5RA 1FSUA 3MK0A 5IJSA 3M8ZA 2ANHA 4FDIA 1HJKA 2W5TA 3A52A 4LRBA 1ALJA 1AJCA 2GLQA 1EJJA 2GSNA 4LR7A 3UN5A 1KHNA 2VQRA 3IGYB 4CYRA 3NKPA 4CYSA 3NKNA 5K4PA 1K7HA 1EQJA 5LQQA 3BDFA 5DLWA 2XRGA 4UORA 1AJBA 1ANJA 4QAXA 1ELZA 1EW9A 3WAYA 3OT9A 3TX0A 2W5SA 5HRTA 4UPHA 1ED9A 2X98A 4B56A 2W8SA 3M8YA 3WAVA 5KXAA 3WAXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GTZ A;  3WBH A;  3IGZ B;  2XR9 A;  1KH7 A;  4ZGA A;  4UPK A;  1ZED A;  3LXQ A;  2GSU A;  4MY4 A;  2RH6 A;  5IJQ A;  1ALI A;  3NKQ A;  1HDH A;  3NKO A;  1KHL A;  4CXU A;  2ZKT A;  1URA A;  4NWX A;  1Y7A A;  3M8W A;  5GOV A;  1URB A;  1B8J A;  4LRF A;  2W5X A;  4TN0 A;  4LR2 A;  4NWJ A;  1E2S P;  3SZZ A;  1ELY A;  1ALH A;  1KH4 A;  1O98 A;  2W5W A;  4YR1 A;  5L0B A;  3IDD A;  4CXK A;  5L0E A;  1ANI A;  1ZEB A;  4ZG7 A;  4LRA A;  3BDH A;  1ELX A;  3NVL A;  1N2L A;  1E3C P;  5LRN A;  3WAW A;  1ED8 A;  1AJA A;  4ZG9 A;  3CMR A;  3MK1 A;  4N7T A;  1Y6V A;  5LRM A;  1HQA A;  3NKR A;  4KM4 A;  3BDG B;  1KHJ A;  3SZY A;  1AJD A;  2IUC B;  4GTX A;  5EGH A;  1E1Z P;  4UOP A;  2G9Y A;  2IFY A;  1EW2 A;  3M7V A;  5LIA A;  3BDG A;  3DPC A;  4KJG A;  2IUC A;  5DLV A;  1N2K A;  1KHK A;  4UPL A;  5DLT A;  2D1G A;  1EI6 A;  2W5V A;  2W5Q A;  4MIV A;  5AJ9 A;  5INH A;  3TWZ A;  5GRR A;  3UNY A;  4CXS A;  3Q3Q A;  3UO0 A;  3T01 A;  3ED4 A;  4ZG6 A;  2GA3 A;  1SHQ A;  3MK2 A;  3T00 A;  1KH9 A;  1ALK A;  4LR9 A;  4KAY A;  3E2D A;  3NKM A;  4LRC A;  4UPI A;  4LRD A;  4UOO A;  1EW8 A;  2GSO A;  3B5Q A;  4GTW A;  5TJ3 A;  4KAV A;  4GTY A;  1ZEF A;  1KH5 A;  1SHN A;  5C66 A;  2W8D A;  4LR8 A;  4MHX A;  1O99 A;  1P49 A;  4LRE A;  3UN2 A;  4FDJ A;  3UN3 A;  3TG0 A;  4LQY A;  3KD8 A;  2QZU A;  3DYC A;  4KJD A;  3T02 A;  1AUK A;  5L0K A;  1E33 P;  5EGE A;  2W5R A;  1FSU A;  3MK0 A;  5IJS A;  3M8Z A;  2ANH A;  4FDI A;  1HJK A;  2W5T A;  3A52 A;  4LRB A;  1ALJ A;  1AJC A;  2GLQ A;  1EJJ A;  2GSN A;  4LR7 A;  3UN5 A;  1KHN A;  2VQR A;  3IGY B;  4CYR A;  3NKP A;  4CYS A;  3NKN A;  5K4P A;  1K7H A;  1EQJ A;  5LQQ A;  3BDF A;  5DLW A;  2XRG A;  4UOR A;  1AJB A;  1ANJ A;  4QAX A;  1ELZ A;  1EW9 A;  3WAY A;  3OT9 A;  3TX0 A;  2W5S A;  5HRT A;  4UPH A;  1ED9 A;  2X98 A;  4B56 A;  2W8S A;  3M8Y A;  3WAV A;  5KXA A;  3WAX A; 
#chains in the Genus database with same CATH topology
 4GTZ A;  3WBH A;  3IGZ B;  2XR9 A;  1KH7 A;  4ZGA A;  4UPK A;  1ZED A;  3LXQ A;  2GSU A;  4MY4 A;  2RH6 A;  5IJQ A;  1ALI A;  3NKQ A;  1HDH A;  3NKO A;  1KHL A;  4CXU A;  2ZKT A;  1URA A;  4NWX A;  1Y7A A;  3M8W A;  5GOV A;  1URB A;  1B8J A;  4LRF A;  2W5X A;  4TN0 A;  4LR2 A;  4NWJ A;  1E2S P;  3SZZ A;  1ELY A;  1ALH A;  1KH4 A;  1O98 A;  2W5W A;  4YR1 A;  5L0B A;  3IDD A;  4CXK A;  5L0E A;  1ANI A;  1ZEB A;  4ZG7 A;  4LRA A;  3BDH A;  1ELX A;  3NVL A;  1N2L A;  1E3C P;  5LRN A;  3WAW A;  1ED8 A;  1AJA A;  4ZG9 A;  3CMR A;  3MK1 A;  4N7T A;  1Y6V A;  5LRM A;  1HQA A;  3NKR A;  4KM4 A;  3BDG B;  1KHJ A;  3SZY A;  1AJD A;  2IUC B;  4GTX A;  5EGH A;  1E1Z P;  4UOP A;  2G9Y A;  2IFY A;  1EW2 A;  3M7V A;  5LIA A;  3BDG A;  3DPC A;  4KJG A;  2IUC A;  5DLV A;  1N2K A;  1KHK A;  4UPL A;  5DLT A;  2D1G A;  1EI6 A;  2W5V A;  2W5Q A;  4MIV A;  5AJ9 A;  5INH A;  3TWZ A;  5GRR A;  3UNY A;  4CXS A;  3Q3Q A;  3UO0 A;  3T01 A;  3ED4 A;  4ZG6 A;  2GA3 A;  1SHQ A;  3MK2 A;  3T00 A;  1KH9 A;  1ALK A;  4LR9 A;  4KAY A;  3E2D A;  3NKM A;  4LRC A;  4UPI A;  4LRD A;  4UOO A;  1EW8 A;  2GSO A;  3B5Q A;  4GTW A;  5TJ3 A;  4KAV A;  4GTY A;  1ZEF A;  1KH5 A;  1SHN A;  5C66 A;  2W8D A;  4LR8 A;  4MHX A;  1O99 A;  1P49 A;  4LRE A;  3UN2 A;  4FDJ A;  3UN3 A;  3TG0 A;  4LQY A;  3KD8 A;  2QZU A;  3DYC A;  4KJD A;  3T02 A;  1AUK A;  5L0K A;  1E33 P;  5EGE A;  2W5R A;  1FSU A;  3MK0 A;  5IJS A;  3M8Z A;  2ANH A;  4FDI A;  1HJK A;  2W5T A;  3A52 A;  4LRB A;  1ALJ A;  1AJC A;  2GLQ A;  1EJJ A;  2GSN A;  4LR7 A;  3UN5 A;  1KHN A;  2VQR A;  3IGY B;  4CYR A;  3NKP A;  4CYS A;  3NKN A;  5K4P A;  1K7H A;  1EQJ A;  5LQQ A;  3BDF A;  5DLW A;  2XRG A;  4UOR A;  1AJB A;  1ANJ A;  4QAX A;  1ELZ A;  1EW9 A;  3WAY A;  3OT9 A;  3TX0 A;  2W5S A;  5HRT A;  4UPH A;  1ED9 A;  2X98 A;  4B56 A;  2W8S A;  3M8Y A;  3WAV A;  5KXA A;  3WAX A; 
#chains in the Genus database with same CATH homology
 4GTZ A;  3WBH A;  3IGZ B;  2XR9 A;  1KH7 A;  4ZGA A;  4UPK A;  1ZED A;  3LXQ A;  2GSU A;  4MY4 A;  2RH6 A;  5IJQ A;  1ALI A;  3NKQ A;  1HDH A;  3NKO A;  1KHL A;  4CXU A;  2ZKT A;  1URA A;  4NWX A;  1Y7A A;  3M8W A;  5GOV A;  1URB A;  1B8J A;  4LRF A;  2W5X A;  4TN0 A;  4LR2 A;  4NWJ A;  1E2S P;  3SZZ A;  1ELY A;  1ALH A;  1KH4 A;  1O98 A;  2W5W A;  4YR1 A;  5L0B A;  3IDD A;  4CXK A;  5L0E A;  1ANI A;  1ZEB A;  4ZG7 A;  4LRA A;  3BDH A;  1ELX A;  3NVL A;  1N2L A;  1E3C P;  5LRN A;  3WAW A;  1ED8 A;  1AJA A;  4ZG9 A;  3CMR A;  3MK1 A;  4N7T A;  1Y6V A;  5LRM A;  1HQA A;  3NKR A;  4KM4 A;  3BDG B;  1KHJ A;  3SZY A;  1AJD A;  2IUC B;  4GTX A;  5EGH A;  1E1Z P;  4UOP A;  2G9Y A;  2IFY A;  1EW2 A;  3M7V A;  5LIA A;  3BDG A;  3DPC A;  4KJG A;  2IUC A;  5DLV A;  1N2K A;  1KHK A;  4UPL A;  5DLT A;  2D1G A;  1EI6 A;  2W5V A;  2W5Q A;  4MIV A;  5AJ9 A;  5INH A;  3TWZ A;  5GRR A;  3UNY A;  4CXS A;  3Q3Q A;  3UO0 A;  3T01 A;  3ED4 A;  4ZG6 A;  2GA3 A;  1SHQ A;  3MK2 A;  3T00 A;  1KH9 A;  1ALK A;  4LR9 A;  4KAY A;  3E2D A;  3NKM A;  4LRC A;  4UPI A;  4LRD A;  4UOO A;  1EW8 A;  2GSO A;  3B5Q A;  4GTW A;  5TJ3 A;  4KAV A;  4GTY A;  1ZEF A;  1KH5 A;  1SHN A;  5C66 A;  2W8D A;  4LR8 A;  4MHX A;  1O99 A;  1P49 A;  4LRE A;  3UN2 A;  4FDJ A;  3UN3 A;  3TG0 A;  4LQY A;  3KD8 A;  2QZU A;  3DYC A;  4KJD A;  3T02 A;  1AUK A;  5L0K A;  1E33 P;  5EGE A;  2W5R A;  1FSU A;  3MK0 A;  5IJS A;  3M8Z A;  2ANH A;  4FDI A;  1HJK A;  2W5T A;  3A52 A;  4LRB A;  1ALJ A;  1AJC A;  2GLQ A;  1EJJ A;  2GSN A;  4LR7 A;  3UN5 A;  1KHN A;  2VQR A;  3IGY B;  4CYR A;  3NKP A;  4CYS A;  3NKN A;  5K4P A;  1K7H A;  1EQJ A;  5LQQ A;  3BDF A;  5DLW A;  2XRG A;  4UOR A;  1AJB A;  1ANJ A;  4QAX A;  1ELZ A;  1EW9 A;  3WAY A;  3OT9 A;  3TX0 A;  2W5S A;  5HRT A;  4UPH A;  1ED9 A;  2X98 A;  4B56 A;  2W8S A;  3M8Y A;  3WAV A;  5KXA A;  3WAX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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