3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
Knots found
sequence length
449
structure length
449
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
total genus 147
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
4LREA 4GTWA 1E2SP 4KJGA 1ELZA 4LRBA 4LR8A 3T00A 4MY4A 5L0EA 5GOVA 2XR9A 1ANIA 1ANJA 1EW2A 2IUCB 4GTYA 1HDHA 1AJAA 2W5RA 4GTXA 5LRMA 3B5QA 1N2LA 2D1GA 3WAVA 1AJCA 5DLWA 4GTZA 1EJJA 2QZUA 2W5VA 5EGHA 5HRTA 3UNYA 1KH4A 5TJ3A 1E33P 5INHA 1O99A 1KH9A 4CYSA 3WAYA 1ALJA 5LQQA 3UN2A 4FDJA 2X98A 3UN3A 3UN5A 1E3CP 3TG0A 3Q3QA 4LR9A 3SZZA 1P49A 1ED9A 2XRGA 3BDGB 3T01A 1SHQA 1ALKA 3BDFA 1Y7AA 4B56A 4KAVA 1ED8A 3IGYB 4LR7A 5EGEA 3TWZA 5LIAA 5GRRA 4UPLA 2W5QA 5DLVA 2W5TA 3M8YA 4ZG6A 4UORA 4MIVA 1Y6VA 3NKOA 1KH5A 2IFYA 4MHXA 2GSOA 5KXAA 4CXUA 3CMRA 4UOOA 2W5WA 4KAYA 1EI6A 1O98A 1AUKA 2W5XA 3MK2A 4KM4A 4UPHA 2W5SA 3MK0A 3MK1A 2G9YA 4UOPA 3BDHA 2IUCA 5IJSA 1N2KA 5IJQA 3NKPA 5L0KA 3DYCA 5LRNA 2W8SA 2GA3A 1KH7A 3T02A 1AJDA 3IDDA 4TN0A 4UPKA 2W8DA 1ZEFA 3DPCA 4UPIA 3ED4A 3NKMA 1URAA 3NKQA 4ZG9A 3LXQA 5DLTA 2ANHA 2GSUA 2GSNA 4KJDA 4QAXA 3WBHA 4NWXA 3WAWA 4NWJA 1URBA 3UO0A 3E2DA 3WAXA 3M8WA 3M7VA 1KHJA 4LRFA 1FSUA 4LQYA 2RH6A 2VQRA 1SHNA 3NKNA 3BDGA 1KHNA 2ZKTA 4LRCA 5AJ9A 5C66A 1AJBA 1HJKA 4LRAA 4LRDA 4CXKA 3M8ZA 4ZG7A 1B8JA 1ELXA 3OT9A 5K4PA 2GLQA 1EQJA 5L0BA 1HQAA 3KD8A 4N7TA 1ELYA 1ALHA 3SZYA 3TX0A 1K7HA 1ALIA 1KHKA 3A52A 4CXSA 1EW8A 3IGZB 1KHLA 4ZGAA 1ZEDA 4FDIA 4CYRA 1EW9A 3NVLA 1ZEBA 3NKRA 4YR1A 1E1ZP 4LR2A
chains in the Genus database with same CATH superfamily
4LREA 4GTWA 1E2SP 4KJGA 1ELZA 4LRBA 4LR8A 3T00A 4MY4A 5L0EA 5GOVA 2XR9A 1ANIA 1ANJA 1EW2A 2IUCB 4GTYA 1HDHA 1AJAA 2W5RA 4GTXA 5LRMA 3B5QA 1N2LA 2D1GA 3WAVA 1AJCA 5DLWA 4GTZA 1EJJA 2QZUA 2W5VA 5EGHA 5HRTA 3UNYA 1KH4A 5TJ3A 1E33P 5INHA 1O99A 1KH9A 4CYSA 3WAYA 1ALJA 5LQQA 3UN2A 4FDJA 2X98A 3UN3A 3UN5A 1E3CP 3TG0A 3Q3QA 4LR9A 3SZZA 1P49A 1ED9A 2XRGA 3BDGB 3T01A 1SHQA 1ALKA 3BDFA 1Y7AA 4B56A 4KAVA 1ED8A 3IGYB 4LR7A 5EGEA 3TWZA 5LIAA 5GRRA 4UPLA 2W5QA 5DLVA 2W5TA 3M8YA 4ZG6A 4UORA 4MIVA 1Y6VA 3NKOA 1KH5A 2IFYA 4MHXA 2GSOA 5KXAA 4CXUA 3CMRA 4UOOA 2W5WA 4KAYA 1EI6A 1O98A 1AUKA 2W5XA 3MK2A 4KM4A 4UPHA 2W5SA 3MK0A 3MK1A 2G9YA 4UOPA 3BDHA 2IUCA 5IJSA 1N2KA 5IJQA 3NKPA 5L0KA 3DYCA 5LRNA 2W8SA 2GA3A 1KH7A 3T02A 1AJDA 3IDDA 4TN0A 4UPKA 2W8DA 1ZEFA 3DPCA 4UPIA 3ED4A 3NKMA 1URAA 3NKQA 4ZG9A 3LXQA 5DLTA 2ANHA 2GSUA 2GSNA 4KJDA 4QAXA 3WBHA 4NWXA 3WAWA 4NWJA 1URBA 3UO0A 3E2DA 3WAXA 3M8WA 3M7VA 1KHJA 4LRFA 1FSUA 4LQYA 2RH6A 2VQRA 1SHNA 3NKNA 3BDGA 1KHNA 2ZKTA 4LRCA 5AJ9A 5C66A 1AJBA 1HJKA 4LRAA 4LRDA 4CXKA 3M8ZA 4ZG7A 1B8JA 1ELXA 3OT9A 5K4PA 2GLQA 1EQJA 5L0BA 1HQAA 3KD8A 4N7TA 1ELYA 1ALHA 3SZYA 3TX0A 1K7HA 1ALIA 1KHKA 3A52A 4CXSA 1EW8A 3IGZB 1KHLA 4ZGAA 1ZEDA 4FDIA 4CYRA 1EW9A 3NVLA 1ZEBA 3NKRA 4YR1A 1E1ZP 4LR2A
chains in the Genus database with same CATH topology
4LREA 4GTWA 1E2SP 4KJGA 1ELZA 4LRBA 4LR8A 3T00A 4MY4A 5L0EA 5GOVA 2XR9A 1ANIA 1ANJA 1EW2A 2IUCB 4GTYA 1HDHA 1AJAA 2W5RA 4GTXA 5LRMA 3B5QA 1N2LA 2D1GA 3WAVA 1AJCA 5DLWA 4GTZA 1EJJA 2QZUA 2W5VA 5EGHA 5HRTA 3UNYA 1KH4A 5TJ3A 1E33P 5INHA 1O99A 1KH9A 4CYSA 3WAYA 1ALJA 5LQQA 3UN2A 4FDJA 2X98A 3UN3A 3UN5A 1E3CP 3TG0A 3Q3QA 4LR9A 3SZZA 1P49A 1ED9A 2XRGA 3BDGB 3T01A 1SHQA 1ALKA 3BDFA 1Y7AA 4B56A 4KAVA 1ED8A 3IGYB 4LR7A 5EGEA 3TWZA 5LIAA 5GRRA 4UPLA 2W5QA 5DLVA 2W5TA 3M8YA 4ZG6A 4UORA 4MIVA 1Y6VA 3NKOA 1KH5A 2IFYA 4MHXA 2GSOA 5KXAA 4CXUA 3CMRA 4UOOA 2W5WA 4KAYA 1EI6A 1O98A 1AUKA 2W5XA 3MK2A 4KM4A 4UPHA 2W5SA 3MK0A 3MK1A 2G9YA 4UOPA 3BDHA 2IUCA 5IJSA 1N2KA 5IJQA 3NKPA 5L0KA 3DYCA 5LRNA 2W8SA 2GA3A 1KH7A 3T02A 1AJDA 3IDDA 4TN0A 4UPKA 2W8DA 1ZEFA 3DPCA 4UPIA 3ED4A 3NKMA 1URAA 3NKQA 4ZG9A 3LXQA 5DLTA 2ANHA 2GSUA 2GSNA 4KJDA 4QAXA 3WBHA 4NWXA 3WAWA 4NWJA 1URBA 3UO0A 3E2DA 3WAXA 3M8WA 3M7VA 1KHJA 4LRFA 1FSUA 4LQYA 2RH6A 2VQRA 1SHNA 3NKNA 3BDGA 1KHNA 2ZKTA 4LRCA 5AJ9A 5C66A 1AJBA 1HJKA 4LRAA 4LRDA 4CXKA 3M8ZA 4ZG7A 1B8JA 1ELXA 3OT9A 5K4PA 2GLQA 1EQJA 5L0BA 1HQAA 3KD8A 4N7TA 1ELYA 1ALHA 3SZYA 3TX0A 1K7HA 1ALIA 1KHKA 3A52A 4CXSA 1EW8A 3IGZB 1KHLA 4ZGAA 1ZEDA 4FDIA 4CYRA 1EW9A 3NVLA 1ZEBA 3NKRA 4YR1A 1E1ZP 4LR2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LRE A;  4GTW A;  1E2S P;  4KJG A;  1ELZ A;  4LRB A;  4LR8 A;  3T00 A;  4MY4 A;  5L0E A;  5GOV A;  2XR9 A;  1ANI A;  1ANJ A;  1EW2 A;  2IUC B;  4GTY A;  1HDH A;  1AJA A;  2W5R A;  4GTX A;  5LRM A;  3B5Q A;  1N2L A;  2D1G A;  3WAV A;  1AJC A;  5DLW A;  4GTZ A;  1EJJ A;  2QZU A;  2W5V A;  5EGH A;  5HRT A;  3UNY A;  1KH4 A;  5TJ3 A;  1E33 P;  5INH A;  1O99 A;  1KH9 A;  4CYS A;  3WAY A;  1ALJ A;  5LQQ A;  3UN2 A;  4FDJ A;  2X98 A;  3UN3 A;  3UN5 A;  1E3C P;  3TG0 A;  3Q3Q A;  4LR9 A;  3SZZ A;  1P49 A;  1ED9 A;  2XRG A;  3BDG B;  3T01 A;  1SHQ A;  1ALK A;  3BDF A;  1Y7A A;  4B56 A;  4KAV A;  1ED8 A;  3IGY B;  4LR7 A;  5EGE A;  3TWZ A;  5LIA A;  5GRR A;  4UPL A;  2W5Q A;  5DLV A;  2W5T A;  3M8Y A;  4ZG6 A;  4UOR A;  4MIV A;  1Y6V A;  3NKO A;  1KH5 A;  2IFY A;  4MHX A;  2GSO A;  5KXA A;  4CXU A;  3CMR A;  4UOO A;  2W5W A;  4KAY A;  1EI6 A;  1O98 A;  1AUK A;  2W5X A;  3MK2 A;  4KM4 A;  4UPH A;  2W5S A;  3MK0 A;  3MK1 A;  2G9Y A;  4UOP A;  3BDH A;  2IUC A;  5IJS A;  1N2K A;  5IJQ A;  3NKP A;  5L0K A;  3DYC A;  5LRN A;  2W8S A;  2GA3 A;  1KH7 A;  3T02 A;  1AJD A;  3IDD A;  4TN0 A;  4UPK A;  2W8D A;  1ZEF A;  3DPC A;  4UPI A;  3ED4 A;  3NKM A;  1URA A;  3NKQ A;  4ZG9 A;  3LXQ A;  5DLT A;  2ANH A;  2GSU A;  2GSN A;  4KJD A;  4QAX A;  3WBH A;  4NWX A;  3WAW A;  4NWJ A;  1URB A;  3UO0 A;  3E2D A;  3WAX A;  3M8W A;  3M7V A;  1KHJ A;  4LRF A;  1FSU A;  4LQY A;  2RH6 A;  2VQR A;  1SHN A;  3NKN A;  3BDG A;  1KHN A;  2ZKT A;  4LRC A;  5AJ9 A;  5C66 A;  1AJB A;  1HJK A;  4LRA A;  4LRD A;  4CXK A;  3M8Z A;  4ZG7 A;  1B8J A;  1ELX A;  3OT9 A;  5K4P A;  2GLQ A;  1EQJ A;  5L0B A;  1HQA A;  3KD8 A;  4N7T A;  1ELY A;  1ALH A;  3SZY A;  3TX0 A;  1K7H A;  1ALI A;  1KHK A;  3A52 A;  4CXS A;  1EW8 A;  3IGZ B;  1KHL A;  4ZGA A;  1ZED A;  4FDI A;  4CYR A;  1EW9 A;  3NVL A;  1ZEB A;  3NKR A;  4YR1 A;  1E1Z P;  4LR2 A; 
#chains in the Genus database with same CATH topology
 4LRE A;  4GTW A;  1E2S P;  4KJG A;  1ELZ A;  4LRB A;  4LR8 A;  3T00 A;  4MY4 A;  5L0E A;  5GOV A;  2XR9 A;  1ANI A;  1ANJ A;  1EW2 A;  2IUC B;  4GTY A;  1HDH A;  1AJA A;  2W5R A;  4GTX A;  5LRM A;  3B5Q A;  1N2L A;  2D1G A;  3WAV A;  1AJC A;  5DLW A;  4GTZ A;  1EJJ A;  2QZU A;  2W5V A;  5EGH A;  5HRT A;  3UNY A;  1KH4 A;  5TJ3 A;  1E33 P;  5INH A;  1O99 A;  1KH9 A;  4CYS A;  3WAY A;  1ALJ A;  5LQQ A;  3UN2 A;  4FDJ A;  2X98 A;  3UN3 A;  3UN5 A;  1E3C P;  3TG0 A;  3Q3Q A;  4LR9 A;  3SZZ A;  1P49 A;  1ED9 A;  2XRG A;  3BDG B;  3T01 A;  1SHQ A;  1ALK A;  3BDF A;  1Y7A A;  4B56 A;  4KAV A;  1ED8 A;  3IGY B;  4LR7 A;  5EGE A;  3TWZ A;  5LIA A;  5GRR A;  4UPL A;  2W5Q A;  5DLV A;  2W5T A;  3M8Y A;  4ZG6 A;  4UOR A;  4MIV A;  1Y6V A;  3NKO A;  1KH5 A;  2IFY A;  4MHX A;  2GSO A;  5KXA A;  4CXU A;  3CMR A;  4UOO A;  2W5W A;  4KAY A;  1EI6 A;  1O98 A;  1AUK A;  2W5X A;  3MK2 A;  4KM4 A;  4UPH A;  2W5S A;  3MK0 A;  3MK1 A;  2G9Y A;  4UOP A;  3BDH A;  2IUC A;  5IJS A;  1N2K A;  5IJQ A;  3NKP A;  5L0K A;  3DYC A;  5LRN A;  2W8S A;  2GA3 A;  1KH7 A;  3T02 A;  1AJD A;  3IDD A;  4TN0 A;  4UPK A;  2W8D A;  1ZEF A;  3DPC A;  4UPI A;  3ED4 A;  3NKM A;  1URA A;  3NKQ A;  4ZG9 A;  3LXQ A;  5DLT A;  2ANH A;  2GSU A;  2GSN A;  4KJD A;  4QAX A;  3WBH A;  4NWX A;  3WAW A;  4NWJ A;  1URB A;  3UO0 A;  3E2D A;  3WAX A;  3M8W A;  3M7V A;  1KHJ A;  4LRF A;  1FSU A;  4LQY A;  2RH6 A;  2VQR A;  1SHN A;  3NKN A;  3BDG A;  1KHN A;  2ZKT A;  4LRC A;  5AJ9 A;  5C66 A;  1AJB A;  1HJK A;  4LRA A;  4LRD A;  4CXK A;  3M8Z A;  4ZG7 A;  1B8J A;  1ELX A;  3OT9 A;  5K4P A;  2GLQ A;  1EQJ A;  5L0B A;  1HQA A;  3KD8 A;  4N7T A;  1ELY A;  1ALH A;  3SZY A;  3TX0 A;  1K7H A;  1ALI A;  1KHK A;  3A52 A;  4CXS A;  1EW8 A;  3IGZ B;  1KHL A;  4ZGA A;  1ZED A;  4FDI A;  4CYR A;  1EW9 A;  3NVL A;  1ZEB A;  3NKR A;  4YR1 A;  1E1Z P;  4LR2 A; 
#chains in the Genus database with same CATH homology
 4LRE A;  4GTW A;  1E2S P;  4KJG A;  1ELZ A;  4LRB A;  4LR8 A;  3T00 A;  4MY4 A;  5L0E A;  5GOV A;  2XR9 A;  1ANI A;  1ANJ A;  1EW2 A;  2IUC B;  4GTY A;  1HDH A;  1AJA A;  2W5R A;  4GTX A;  5LRM A;  3B5Q A;  1N2L A;  2D1G A;  3WAV A;  1AJC A;  5DLW A;  4GTZ A;  1EJJ A;  2QZU A;  2W5V A;  5EGH A;  5HRT A;  3UNY A;  1KH4 A;  5TJ3 A;  1E33 P;  5INH A;  1O99 A;  1KH9 A;  4CYS A;  3WAY A;  1ALJ A;  5LQQ A;  3UN2 A;  4FDJ A;  2X98 A;  3UN3 A;  3UN5 A;  1E3C P;  3TG0 A;  3Q3Q A;  4LR9 A;  3SZZ A;  1P49 A;  1ED9 A;  2XRG A;  3BDG B;  3T01 A;  1SHQ A;  1ALK A;  3BDF A;  1Y7A A;  4B56 A;  4KAV A;  1ED8 A;  3IGY B;  4LR7 A;  5EGE A;  3TWZ A;  5LIA A;  5GRR A;  4UPL A;  2W5Q A;  5DLV A;  2W5T A;  3M8Y A;  4ZG6 A;  4UOR A;  4MIV A;  1Y6V A;  3NKO A;  1KH5 A;  2IFY A;  4MHX A;  2GSO A;  5KXA A;  4CXU A;  3CMR A;  4UOO A;  2W5W A;  4KAY A;  1EI6 A;  1O98 A;  1AUK A;  2W5X A;  3MK2 A;  4KM4 A;  4UPH A;  2W5S A;  3MK0 A;  3MK1 A;  2G9Y A;  4UOP A;  3BDH A;  2IUC A;  5IJS A;  1N2K A;  5IJQ A;  3NKP A;  5L0K A;  3DYC A;  5LRN A;  2W8S A;  2GA3 A;  1KH7 A;  3T02 A;  1AJD A;  3IDD A;  4TN0 A;  4UPK A;  2W8D A;  1ZEF A;  3DPC A;  4UPI A;  3ED4 A;  3NKM A;  1URA A;  3NKQ A;  4ZG9 A;  3LXQ A;  5DLT A;  2ANH A;  2GSU A;  2GSN A;  4KJD A;  4QAX A;  3WBH A;  4NWX A;  3WAW A;  4NWJ A;  1URB A;  3UO0 A;  3E2D A;  3WAX A;  3M8W A;  3M7V A;  1KHJ A;  4LRF A;  1FSU A;  4LQY A;  2RH6 A;  2VQR A;  1SHN A;  3NKN A;  3BDG A;  1KHN A;  2ZKT A;  4LRC A;  5AJ9 A;  5C66 A;  1AJB A;  1HJK A;  4LRA A;  4LRD A;  4CXK A;  3M8Z A;  4ZG7 A;  1B8J A;  1ELX A;  3OT9 A;  5K4P A;  2GLQ A;  1EQJ A;  5L0B A;  1HQA A;  3KD8 A;  4N7T A;  1ELY A;  1ALH A;  3SZY A;  3TX0 A;  1K7H A;  1ALI A;  1KHK A;  3A52 A;  4CXS A;  1EW8 A;  3IGZ B;  1KHL A;  4ZGA A;  1ZED A;  4FDI A;  4CYR A;  1EW9 A;  3NVL A;  1ZEB A;  3NKR A;  4YR1 A;  1E1Z P;  4LR2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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