3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
Knots found
sequence length
449
structure length
449
Chain Sequence
b'PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 147
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
4KJGA 2QZUA 3OT9A 3ED4A 2GA3A 1B8JA 3M7VA 2W8DA 4GTWA 4CYRA 1N2LA 1EW8A 4LR7A 2W5TA 5L0KA 4CXUA 2IFYA 4KAVA 4UPLA 4LR2A 2W5RA 3E2DA 2XR9A 1N2KA 1E33P 3DYCA 1KH9A 1EW2A 1HQAA 1ZEDA 5C66A 3T00A 1AJAA 1Y6VA 3TWZA 4CXKA 1E1ZP 5K4PA 2GLQA 3NKRA 1EI6A 4ZG6A 5LQQA 1ELZA 5IJQA 4UPHA 4ZG7A 1KHLA 2GSUA 4MY4A 2W5SA 1ALJA 5EGHA 4CXSA 3A52A 1KH4A 1AJDA 3UN2A 1HJKA 2RH6A 1ELYA 2VQRA 5TJ3A 3WAYA 4ZG9A 4LREA 4KJDA 4LQYA 4KM4A 1URBA 2ZKTA 1ED8A 4LR9A 1KHKA 1KH7A 2W5QA 4UOPA 2IUCA 5DLWA 4KAYA 2IUCB 1K7HA 1SHNA 2X98A 4LRDA 3TG0A 2W5WA 5LIAA 1ANIA 2W8SA 1KHNA 1AJBA 3M8WA 3WAVA 1ANJA 5LRNA 3LXQA 3BDHA 3NKQA 2GSOA 4MHXA 3IGYB 5EGEA 4UOOA 1EJJA 1HDHA 4GTYA 1ZEBA 5IJSA 3MK0A 1ALIA 4NWJA 4FDJA 3Q3QA 5LRMA 3UN5A 3NKPA 4LRCA 4TN0A 4UPKA 3UO0A 3B5QA 2W5VA 3T02A 4LRAA 3WBHA 4N7TA 1URAA 1KHJA 4LR8A 5AJ9A 3SZYA 3BDFA 5DLVA 1ALHA 4ZGAA 3IDDA 3M8ZA 1EQJA 3MK2A 3TX0A 1E2SP 5L0EA 1P49A 3KD8A 3IGZB 2XRGA 4UORA 4B56A 3NKMA 1FSUA 3T01A 4MIVA 1ED9A 4NWXA 1ELXA 1ALKA 4FDIA 3NKNA 4GTXA 5INHA 2GSNA 3M8YA 1Y7AA 5KXAA 3UNYA 1AUKA 3NKOA 1AJCA 4LRFA 1ZEFA 4QAXA 3BDGA 2ANHA 5DLTA 4GTZA 3BDGB 2W5XA 4CYSA 3SZZA 3MK1A 5HRTA 4YR1A 2D1GA 1E3CP 3DPCA 3WAWA 5GRRA 4UPIA 1SHQA 1O98A 4LRBA 5GOVA 3NVLA 3CMRA 3UN3A 2G9YA 5L0BA 1O99A 1EW9A 1KH5A 3WAXA
chains in the Genus database with same CATH superfamily
4KJGA 2QZUA 3OT9A 3ED4A 2GA3A 1B8JA 3M7VA 2W8DA 4GTWA 4CYRA 1N2LA 1EW8A 4LR7A 2W5TA 5L0KA 4CXUA 2IFYA 4KAVA 4UPLA 4LR2A 2W5RA 3E2DA 2XR9A 1N2KA 1E33P 3DYCA 1KH9A 1EW2A 1HQAA 1ZEDA 5C66A 3T00A 1AJAA 1Y6VA 3TWZA 4CXKA 1E1ZP 5K4PA 2GLQA 3NKRA 1EI6A 4ZG6A 5LQQA 1ELZA 5IJQA 4UPHA 4ZG7A 1KHLA 2GSUA 4MY4A 2W5SA 1ALJA 5EGHA 4CXSA 3A52A 1KH4A 1AJDA 3UN2A 1HJKA 2RH6A 1ELYA 2VQRA 5TJ3A 3WAYA 4ZG9A 4LREA 4KJDA 4LQYA 4KM4A 1URBA 2ZKTA 1ED8A 4LR9A 1KHKA 1KH7A 2W5QA 4UOPA 2IUCA 5DLWA 4KAYA 2IUCB 1K7HA 1SHNA 2X98A 4LRDA 3TG0A 2W5WA 5LIAA 1ANIA 2W8SA 1KHNA 1AJBA 3M8WA 3WAVA 1ANJA 5LRNA 3LXQA 3BDHA 3NKQA 2GSOA 4MHXA 3IGYB 5EGEA 4UOOA 1EJJA 1HDHA 4GTYA 1ZEBA 5IJSA 3MK0A 1ALIA 4NWJA 4FDJA 3Q3QA 5LRMA 3UN5A 3NKPA 4LRCA 4TN0A 4UPKA 3UO0A 3B5QA 2W5VA 3T02A 4LRAA 3WBHA 4N7TA 1URAA 1KHJA 4LR8A 5AJ9A 3SZYA 3BDFA 5DLVA 1ALHA 4ZGAA 3IDDA 3M8ZA 1EQJA 3MK2A 3TX0A 1E2SP 5L0EA 1P49A 3KD8A 3IGZB 2XRGA 4UORA 4B56A 3NKMA 1FSUA 3T01A 4MIVA 1ED9A 4NWXA 1ELXA 1ALKA 4FDIA 3NKNA 4GTXA 5INHA 2GSNA 3M8YA 1Y7AA 5KXAA 3UNYA 1AUKA 3NKOA 1AJCA 4LRFA 1ZEFA 4QAXA 3BDGA 2ANHA 5DLTA 4GTZA 3BDGB 2W5XA 4CYSA 3SZZA 3MK1A 5HRTA 4YR1A 2D1GA 1E3CP 3DPCA 3WAWA 5GRRA 4UPIA 1SHQA 1O98A 4LRBA 5GOVA 3NVLA 3CMRA 3UN3A 2G9YA 5L0BA 1O99A 1EW9A 1KH5A 3WAXA
chains in the Genus database with same CATH topology
4KJGA 2QZUA 3OT9A 3ED4A 2GA3A 1B8JA 3M7VA 2W8DA 4GTWA 4CYRA 1N2LA 1EW8A 4LR7A 2W5TA 5L0KA 4CXUA 2IFYA 4KAVA 4UPLA 4LR2A 2W5RA 3E2DA 2XR9A 1N2KA 1E33P 3DYCA 1KH9A 1EW2A 1HQAA 1ZEDA 5C66A 3T00A 1AJAA 1Y6VA 3TWZA 4CXKA 1E1ZP 5K4PA 2GLQA 3NKRA 1EI6A 4ZG6A 5LQQA 1ELZA 5IJQA 4UPHA 4ZG7A 1KHLA 2GSUA 4MY4A 2W5SA 1ALJA 5EGHA 4CXSA 3A52A 1KH4A 1AJDA 3UN2A 1HJKA 2RH6A 1ELYA 2VQRA 5TJ3A 3WAYA 4ZG9A 4LREA 4KJDA 4LQYA 4KM4A 1URBA 2ZKTA 1ED8A 4LR9A 1KHKA 1KH7A 2W5QA 4UOPA 2IUCA 5DLWA 4KAYA 2IUCB 1K7HA 1SHNA 2X98A 4LRDA 3TG0A 2W5WA 5LIAA 1ANIA 2W8SA 1KHNA 1AJBA 3M8WA 3WAVA 1ANJA 5LRNA 3LXQA 3BDHA 3NKQA 2GSOA 4MHXA 3IGYB 5EGEA 4UOOA 1EJJA 1HDHA 4GTYA 1ZEBA 5IJSA 3MK0A 1ALIA 4NWJA 4FDJA 3Q3QA 5LRMA 3UN5A 3NKPA 4LRCA 4TN0A 4UPKA 3UO0A 3B5QA 2W5VA 3T02A 4LRAA 3WBHA 4N7TA 1URAA 1KHJA 4LR8A 5AJ9A 3SZYA 3BDFA 5DLVA 1ALHA 4ZGAA 3IDDA 3M8ZA 1EQJA 3MK2A 3TX0A 1E2SP 5L0EA 1P49A 3KD8A 3IGZB 2XRGA 4UORA 4B56A 3NKMA 1FSUA 3T01A 4MIVA 1ED9A 4NWXA 1ELXA 1ALKA 4FDIA 3NKNA 4GTXA 5INHA 2GSNA 3M8YA 1Y7AA 5KXAA 3UNYA 1AUKA 3NKOA 1AJCA 4LRFA 1ZEFA 4QAXA 3BDGA 2ANHA 5DLTA 4GTZA 3BDGB 2W5XA 4CYSA 3SZZA 3MK1A 5HRTA 4YR1A 2D1GA 1E3CP 3DPCA 3WAWA 5GRRA 4UPIA 1SHQA 1O98A 4LRBA 5GOVA 3NVLA 3CMRA 3UN3A 2G9YA 5L0BA 1O99A 1EW9A 1KH5A 3WAXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KJG A;  2QZU A;  3OT9 A;  3ED4 A;  2GA3 A;  1B8J A;  3M7V A;  2W8D A;  4GTW A;  4CYR A;  1N2L A;  1EW8 A;  4LR7 A;  2W5T A;  5L0K A;  4CXU A;  2IFY A;  4KAV A;  4UPL A;  4LR2 A;  2W5R A;  3E2D A;  2XR9 A;  1N2K A;  1E33 P;  3DYC A;  1KH9 A;  1EW2 A;  1HQA A;  1ZED A;  5C66 A;  3T00 A;  1AJA A;  1Y6V A;  3TWZ A;  4CXK A;  1E1Z P;  5K4P A;  2GLQ A;  3NKR A;  1EI6 A;  4ZG6 A;  5LQQ A;  1ELZ A;  5IJQ A;  4UPH A;  4ZG7 A;  1KHL A;  2GSU A;  4MY4 A;  2W5S A;  1ALJ A;  5EGH A;  4CXS A;  3A52 A;  1KH4 A;  1AJD A;  3UN2 A;  1HJK A;  2RH6 A;  1ELY A;  2VQR A;  5TJ3 A;  3WAY A;  4ZG9 A;  4LRE A;  4KJD A;  4LQY A;  4KM4 A;  1URB A;  2ZKT A;  1ED8 A;  4LR9 A;  1KHK A;  1KH7 A;  2W5Q A;  4UOP A;  2IUC A;  5DLW A;  4KAY A;  2IUC B;  1K7H A;  1SHN A;  2X98 A;  4LRD A;  3TG0 A;  2W5W A;  5LIA A;  1ANI A;  2W8S A;  1KHN A;  1AJB A;  3M8W A;  3WAV A;  1ANJ A;  5LRN A;  3LXQ A;  3BDH A;  3NKQ A;  2GSO A;  4MHX A;  3IGY B;  5EGE A;  4UOO A;  1EJJ A;  1HDH A;  4GTY A;  1ZEB A;  5IJS A;  3MK0 A;  1ALI A;  4NWJ A;  4FDJ A;  3Q3Q A;  5LRM A;  3UN5 A;  3NKP A;  4LRC A;  4TN0 A;  4UPK A;  3UO0 A;  3B5Q A;  2W5V A;  3T02 A;  4LRA A;  3WBH A;  4N7T A;  1URA A;  1KHJ A;  4LR8 A;  5AJ9 A;  3SZY A;  3BDF A;  5DLV A;  1ALH A;  4ZGA A;  3IDD A;  3M8Z A;  1EQJ A;  3MK2 A;  3TX0 A;  1E2S P;  5L0E A;  1P49 A;  3KD8 A;  3IGZ B;  2XRG A;  4UOR A;  4B56 A;  3NKM A;  1FSU A;  3T01 A;  4MIV A;  1ED9 A;  4NWX A;  1ELX A;  1ALK A;  4FDI A;  3NKN A;  4GTX A;  5INH A;  2GSN A;  3M8Y A;  1Y7A A;  5KXA A;  3UNY A;  1AUK A;  3NKO A;  1AJC A;  4LRF A;  1ZEF A;  4QAX A;  3BDG A;  2ANH A;  5DLT A;  4GTZ A;  3BDG B;  2W5X A;  4CYS A;  3SZZ A;  3MK1 A;  5HRT A;  4YR1 A;  2D1G A;  1E3C P;  3DPC A;  3WAW A;  5GRR A;  4UPI A;  1SHQ A;  1O98 A;  4LRB A;  5GOV A;  3NVL A;  3CMR A;  3UN3 A;  2G9Y A;  5L0B A;  1O99 A;  1EW9 A;  1KH5 A;  3WAX A; 
#chains in the Genus database with same CATH topology
 4KJG A;  2QZU A;  3OT9 A;  3ED4 A;  2GA3 A;  1B8J A;  3M7V A;  2W8D A;  4GTW A;  4CYR A;  1N2L A;  1EW8 A;  4LR7 A;  2W5T A;  5L0K A;  4CXU A;  2IFY A;  4KAV A;  4UPL A;  4LR2 A;  2W5R A;  3E2D A;  2XR9 A;  1N2K A;  1E33 P;  3DYC A;  1KH9 A;  1EW2 A;  1HQA A;  1ZED A;  5C66 A;  3T00 A;  1AJA A;  1Y6V A;  3TWZ A;  4CXK A;  1E1Z P;  5K4P A;  2GLQ A;  3NKR A;  1EI6 A;  4ZG6 A;  5LQQ A;  1ELZ A;  5IJQ A;  4UPH A;  4ZG7 A;  1KHL A;  2GSU A;  4MY4 A;  2W5S A;  1ALJ A;  5EGH A;  4CXS A;  3A52 A;  1KH4 A;  1AJD A;  3UN2 A;  1HJK A;  2RH6 A;  1ELY A;  2VQR A;  5TJ3 A;  3WAY A;  4ZG9 A;  4LRE A;  4KJD A;  4LQY A;  4KM4 A;  1URB A;  2ZKT A;  1ED8 A;  4LR9 A;  1KHK A;  1KH7 A;  2W5Q A;  4UOP A;  2IUC A;  5DLW A;  4KAY A;  2IUC B;  1K7H A;  1SHN A;  2X98 A;  4LRD A;  3TG0 A;  2W5W A;  5LIA A;  1ANI A;  2W8S A;  1KHN A;  1AJB A;  3M8W A;  3WAV A;  1ANJ A;  5LRN A;  3LXQ A;  3BDH A;  3NKQ A;  2GSO A;  4MHX A;  3IGY B;  5EGE A;  4UOO A;  1EJJ A;  1HDH A;  4GTY A;  1ZEB A;  5IJS A;  3MK0 A;  1ALI A;  4NWJ A;  4FDJ A;  3Q3Q A;  5LRM A;  3UN5 A;  3NKP A;  4LRC A;  4TN0 A;  4UPK A;  3UO0 A;  3B5Q A;  2W5V A;  3T02 A;  4LRA A;  3WBH A;  4N7T A;  1URA A;  1KHJ A;  4LR8 A;  5AJ9 A;  3SZY A;  3BDF A;  5DLV A;  1ALH A;  4ZGA A;  3IDD A;  3M8Z A;  1EQJ A;  3MK2 A;  3TX0 A;  1E2S P;  5L0E A;  1P49 A;  3KD8 A;  3IGZ B;  2XRG A;  4UOR A;  4B56 A;  3NKM A;  1FSU A;  3T01 A;  4MIV A;  1ED9 A;  4NWX A;  1ELX A;  1ALK A;  4FDI A;  3NKN A;  4GTX A;  5INH A;  2GSN A;  3M8Y A;  1Y7A A;  5KXA A;  3UNY A;  1AUK A;  3NKO A;  1AJC A;  4LRF A;  1ZEF A;  4QAX A;  3BDG A;  2ANH A;  5DLT A;  4GTZ A;  3BDG B;  2W5X A;  4CYS A;  3SZZ A;  3MK1 A;  5HRT A;  4YR1 A;  2D1G A;  1E3C P;  3DPC A;  3WAW A;  5GRR A;  4UPI A;  1SHQ A;  1O98 A;  4LRB A;  5GOV A;  3NVL A;  3CMR A;  3UN3 A;  2G9Y A;  5L0B A;  1O99 A;  1EW9 A;  1KH5 A;  3WAX A; 
#chains in the Genus database with same CATH homology
 4KJG A;  2QZU A;  3OT9 A;  3ED4 A;  2GA3 A;  1B8J A;  3M7V A;  2W8D A;  4GTW A;  4CYR A;  1N2L A;  1EW8 A;  4LR7 A;  2W5T A;  5L0K A;  4CXU A;  2IFY A;  4KAV A;  4UPL A;  4LR2 A;  2W5R A;  3E2D A;  2XR9 A;  1N2K A;  1E33 P;  3DYC A;  1KH9 A;  1EW2 A;  1HQA A;  1ZED A;  5C66 A;  3T00 A;  1AJA A;  1Y6V A;  3TWZ A;  4CXK A;  1E1Z P;  5K4P A;  2GLQ A;  3NKR A;  1EI6 A;  4ZG6 A;  5LQQ A;  1ELZ A;  5IJQ A;  4UPH A;  4ZG7 A;  1KHL A;  2GSU A;  4MY4 A;  2W5S A;  1ALJ A;  5EGH A;  4CXS A;  3A52 A;  1KH4 A;  1AJD A;  3UN2 A;  1HJK A;  2RH6 A;  1ELY A;  2VQR A;  5TJ3 A;  3WAY A;  4ZG9 A;  4LRE A;  4KJD A;  4LQY A;  4KM4 A;  1URB A;  2ZKT A;  1ED8 A;  4LR9 A;  1KHK A;  1KH7 A;  2W5Q A;  4UOP A;  2IUC A;  5DLW A;  4KAY A;  2IUC B;  1K7H A;  1SHN A;  2X98 A;  4LRD A;  3TG0 A;  2W5W A;  5LIA A;  1ANI A;  2W8S A;  1KHN A;  1AJB A;  3M8W A;  3WAV A;  1ANJ A;  5LRN A;  3LXQ A;  3BDH A;  3NKQ A;  2GSO A;  4MHX A;  3IGY B;  5EGE A;  4UOO A;  1EJJ A;  1HDH A;  4GTY A;  1ZEB A;  5IJS A;  3MK0 A;  1ALI A;  4NWJ A;  4FDJ A;  3Q3Q A;  5LRM A;  3UN5 A;  3NKP A;  4LRC A;  4TN0 A;  4UPK A;  3UO0 A;  3B5Q A;  2W5V A;  3T02 A;  4LRA A;  3WBH A;  4N7T A;  1URA A;  1KHJ A;  4LR8 A;  5AJ9 A;  3SZY A;  3BDF A;  5DLV A;  1ALH A;  4ZGA A;  3IDD A;  3M8Z A;  1EQJ A;  3MK2 A;  3TX0 A;  1E2S P;  5L0E A;  1P49 A;  3KD8 A;  3IGZ B;  2XRG A;  4UOR A;  4B56 A;  3NKM A;  1FSU A;  3T01 A;  4MIV A;  1ED9 A;  4NWX A;  1ELX A;  1ALK A;  4FDI A;  3NKN A;  4GTX A;  5INH A;  2GSN A;  3M8Y A;  1Y7A A;  5KXA A;  3UNY A;  1AUK A;  3NKO A;  1AJC A;  4LRF A;  1ZEF A;  4QAX A;  3BDG A;  2ANH A;  5DLT A;  4GTZ A;  3BDG B;  2W5X A;  4CYS A;  3SZZ A;  3MK1 A;  5HRT A;  4YR1 A;  2D1G A;  1E3C P;  3DPC A;  3WAW A;  5GRR A;  4UPI A;  1SHQ A;  1O98 A;  4LRB A;  5GOV A;  3NVL A;  3CMR A;  3UN3 A;  2G9Y A;  5L0B A;  1O99 A;  1EW9 A;  1KH5 A;  3WAX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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