3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Total Genus 147
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
Knots found
sequence length
449
structure length
449
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 147
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
1AJDA 4LQYA 1E3CP 1KH5A 3UNYA 1ELZA 5LRMA 1AUKA 4FDIA 3BDGB 2GSUA 2X98A 5C66A 2W5WA 4ZG7A 1KHLA 3WAXA 3IGZB 5L0KA 4UPHA 3ED4A 5LQQA 5L0BA 1HJKA 4CYRA 5L0EA 3T01A 1HQAA 1URAA 1EW2A 3IGYB 4MIVA 1ALJA 3OT9A 4GTWA 3BDFA 1E33P 3M7VA 2G9YA 2W8SA 3MK0A 3SZYA 3CMRA 2QZUA 5AJ9A 3UN2A 3TG0A 2GA3A 4NWXA 4CXUA 1ZEFA 3NKNA 4TN0A 1KHNA 1ANIA 1HDHA 1K7HA 4LR7A 3T00A 3IDDA 3SZZA 2GSOA 3WAVA 1AJCA 3WBHA 5LIAA 4GTXA 1EI6A 4CXSA 4UOPA 3BDGA 5KXAA 1ELXA 4UORA 1KHJA 3UO0A 1ALKA 1ZEBA 5DLWA 2GLQA 4GTYA 3A52A 1AJBA 2W5QA 3M8YA 3NKOA 4KM4A 4N7TA 3LXQA 5GOVA 1Y6VA 1EW8A 2GSNA 2W5RA 4YR1A 5LRNA 4LRBA 1Y7AA 5EGEA 2IUCA 3NVLA 3KD8A 2IUCB 1ED8A 3E2DA 4ZGAA 4CYSA 5TJ3A 4LRFA 4NWJA 4ZG6A 5INHA 1O99A 4UPLA 3TWZA 4GTZA 1P49A 4CXKA 4LR9A 3DYCA 2IFYA 2W8DA 4KAVA 5DLVA 4LRAA 2RH6A 4LRDA 1URBA 1SHQA 5IJQA 3NKPA 4KJGA 4MY4A 3B5QA 1EQJA 1KH9A 3M8WA 2XR9A 1E1ZP 3Q3QA 4LR8A 1KH7A 2W5XA 3NKRA 4QAXA 2W5VA 4KAYA 3BDHA 5IJSA 3NKQA 1KHKA 1ED9A 4KJDA 5EGHA 1ZEDA 5DLTA 1O98A 4B56A 1EJJA 3TX0A 4ZG9A 4UOOA 3UN3A 1ALHA 4LREA 4FDJA 5K4PA 1SHNA 4UPIA 5HRTA 3UN5A 3M8ZA 1ELYA 3MK1A 3T02A 4LR2A 1B8JA 2ZKTA 2XRGA 3WAWA 1ANJA 1E2SP 4LRCA 1N2LA 3DPCA 3MK2A 1KH4A 3NKMA 3WAYA 2W5SA 1AJAA 4MHXA 1N2KA 4UPKA 1FSUA 2VQRA 2W5TA 2ANHA 1EW9A 2D1GA 1ALIA 5GRRA
chains in the Genus database with same CATH superfamily
1AJDA 4LQYA 1E3CP 1KH5A 3UNYA 1ELZA 5LRMA 1AUKA 4FDIA 3BDGB 2GSUA 2X98A 5C66A 2W5WA 4ZG7A 1KHLA 3WAXA 3IGZB 5L0KA 4UPHA 3ED4A 5LQQA 5L0BA 1HJKA 4CYRA 5L0EA 3T01A 1HQAA 1URAA 1EW2A 3IGYB 4MIVA 1ALJA 3OT9A 4GTWA 3BDFA 1E33P 3M7VA 2G9YA 2W8SA 3MK0A 3SZYA 3CMRA 2QZUA 5AJ9A 3UN2A 3TG0A 2GA3A 4NWXA 4CXUA 1ZEFA 3NKNA 4TN0A 1KHNA 1ANIA 1HDHA 1K7HA 4LR7A 3T00A 3IDDA 3SZZA 2GSOA 3WAVA 1AJCA 3WBHA 5LIAA 4GTXA 1EI6A 4CXSA 4UOPA 3BDGA 5KXAA 1ELXA 4UORA 1KHJA 3UO0A 1ALKA 1ZEBA 5DLWA 2GLQA 4GTYA 3A52A 1AJBA 2W5QA 3M8YA 3NKOA 4KM4A 4N7TA 3LXQA 5GOVA 1Y6VA 1EW8A 2GSNA 2W5RA 4YR1A 5LRNA 4LRBA 1Y7AA 5EGEA 2IUCA 3NVLA 3KD8A 2IUCB 1ED8A 3E2DA 4ZGAA 4CYSA 5TJ3A 4LRFA 4NWJA 4ZG6A 5INHA 1O99A 4UPLA 3TWZA 4GTZA 1P49A 4CXKA 4LR9A 3DYCA 2IFYA 2W8DA 4KAVA 5DLVA 4LRAA 2RH6A 4LRDA 1URBA 1SHQA 5IJQA 3NKPA 4KJGA 4MY4A 3B5QA 1EQJA 1KH9A 3M8WA 2XR9A 1E1ZP 3Q3QA 4LR8A 1KH7A 2W5XA 3NKRA 4QAXA 2W5VA 4KAYA 3BDHA 5IJSA 3NKQA 1KHKA 1ED9A 4KJDA 5EGHA 1ZEDA 5DLTA 1O98A 4B56A 1EJJA 3TX0A 4ZG9A 4UOOA 3UN3A 1ALHA 4LREA 4FDJA 5K4PA 1SHNA 4UPIA 5HRTA 3UN5A 3M8ZA 1ELYA 3MK1A 3T02A 4LR2A 1B8JA 2ZKTA 2XRGA 3WAWA 1ANJA 1E2SP 4LRCA 1N2LA 3DPCA 3MK2A 1KH4A 3NKMA 3WAYA 2W5SA 1AJAA 4MHXA 1N2KA 4UPKA 1FSUA 2VQRA 2W5TA 2ANHA 1EW9A 2D1GA 1ALIA 5GRRA
chains in the Genus database with same CATH topology
1AJDA 4LQYA 1E3CP 1KH5A 3UNYA 1ELZA 5LRMA 1AUKA 4FDIA 3BDGB 2GSUA 2X98A 5C66A 2W5WA 4ZG7A 1KHLA 3WAXA 3IGZB 5L0KA 4UPHA 3ED4A 5LQQA 5L0BA 1HJKA 4CYRA 5L0EA 3T01A 1HQAA 1URAA 1EW2A 3IGYB 4MIVA 1ALJA 3OT9A 4GTWA 3BDFA 1E33P 3M7VA 2G9YA 2W8SA 3MK0A 3SZYA 3CMRA 2QZUA 5AJ9A 3UN2A 3TG0A 2GA3A 4NWXA 4CXUA 1ZEFA 3NKNA 4TN0A 1KHNA 1ANIA 1HDHA 1K7HA 4LR7A 3T00A 3IDDA 3SZZA 2GSOA 3WAVA 1AJCA 3WBHA 5LIAA 4GTXA 1EI6A 4CXSA 4UOPA 3BDGA 5KXAA 1ELXA 4UORA 1KHJA 3UO0A 1ALKA 1ZEBA 5DLWA 2GLQA 4GTYA 3A52A 1AJBA 2W5QA 3M8YA 3NKOA 4KM4A 4N7TA 3LXQA 5GOVA 1Y6VA 1EW8A 2GSNA 2W5RA 4YR1A 5LRNA 4LRBA 1Y7AA 5EGEA 2IUCA 3NVLA 3KD8A 2IUCB 1ED8A 3E2DA 4ZGAA 4CYSA 5TJ3A 4LRFA 4NWJA 4ZG6A 5INHA 1O99A 4UPLA 3TWZA 4GTZA 1P49A 4CXKA 4LR9A 3DYCA 2IFYA 2W8DA 4KAVA 5DLVA 4LRAA 2RH6A 4LRDA 1URBA 1SHQA 5IJQA 3NKPA 4KJGA 4MY4A 3B5QA 1EQJA 1KH9A 3M8WA 2XR9A 1E1ZP 3Q3QA 4LR8A 1KH7A 2W5XA 3NKRA 4QAXA 2W5VA 4KAYA 3BDHA 5IJSA 3NKQA 1KHKA 1ED9A 4KJDA 5EGHA 1ZEDA 5DLTA 1O98A 4B56A 1EJJA 3TX0A 4ZG9A 4UOOA 3UN3A 1ALHA 4LREA 4FDJA 5K4PA 1SHNA 4UPIA 5HRTA 3UN5A 3M8ZA 1ELYA 3MK1A 3T02A 4LR2A 1B8JA 2ZKTA 2XRGA 3WAWA 1ANJA 1E2SP 4LRCA 1N2LA 3DPCA 3MK2A 1KH4A 3NKMA 3WAYA 2W5SA 1AJAA 4MHXA 1N2KA 4UPKA 1FSUA 2VQRA 2W5TA 2ANHA 1EW9A 2D1GA 1ALIA 5GRRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AJD A;  4LQY A;  1E3C P;  1KH5 A;  3UNY A;  1ELZ A;  5LRM A;  1AUK A;  4FDI A;  3BDG B;  2GSU A;  2X98 A;  5C66 A;  2W5W A;  4ZG7 A;  1KHL A;  3WAX A;  3IGZ B;  5L0K A;  4UPH A;  3ED4 A;  5LQQ A;  5L0B A;  1HJK A;  4CYR A;  5L0E A;  3T01 A;  1HQA A;  1URA A;  1EW2 A;  3IGY B;  4MIV A;  1ALJ A;  3OT9 A;  4GTW A;  3BDF A;  1E33 P;  3M7V A;  2G9Y A;  2W8S A;  3MK0 A;  3SZY A;  3CMR A;  2QZU A;  5AJ9 A;  3UN2 A;  3TG0 A;  2GA3 A;  4NWX A;  4CXU A;  1ZEF A;  3NKN A;  4TN0 A;  1KHN A;  1ANI A;  1HDH A;  1K7H A;  4LR7 A;  3T00 A;  3IDD A;  3SZZ A;  2GSO A;  3WAV A;  1AJC A;  3WBH A;  5LIA A;  4GTX A;  1EI6 A;  4CXS A;  4UOP A;  3BDG A;  5KXA A;  1ELX A;  4UOR A;  1KHJ A;  3UO0 A;  1ALK A;  1ZEB A;  5DLW A;  2GLQ A;  4GTY A;  3A52 A;  1AJB A;  2W5Q A;  3M8Y A;  3NKO A;  4KM4 A;  4N7T A;  3LXQ A;  5GOV A;  1Y6V A;  1EW8 A;  2GSN A;  2W5R A;  4YR1 A;  5LRN A;  4LRB A;  1Y7A A;  5EGE A;  2IUC A;  3NVL A;  3KD8 A;  2IUC B;  1ED8 A;  3E2D A;  4ZGA A;  4CYS A;  5TJ3 A;  4LRF A;  4NWJ A;  4ZG6 A;  5INH A;  1O99 A;  4UPL A;  3TWZ A;  4GTZ A;  1P49 A;  4CXK A;  4LR9 A;  3DYC A;  2IFY A;  2W8D A;  4KAV A;  5DLV A;  4LRA A;  2RH6 A;  4LRD A;  1URB A;  1SHQ A;  5IJQ A;  3NKP A;  4KJG A;  4MY4 A;  3B5Q A;  1EQJ A;  1KH9 A;  3M8W A;  2XR9 A;  1E1Z P;  3Q3Q A;  4LR8 A;  1KH7 A;  2W5X A;  3NKR A;  4QAX A;  2W5V A;  4KAY A;  3BDH A;  5IJS A;  3NKQ A;  1KHK A;  1ED9 A;  4KJD A;  5EGH A;  1ZED A;  5DLT A;  1O98 A;  4B56 A;  1EJJ A;  3TX0 A;  4ZG9 A;  4UOO A;  3UN3 A;  1ALH A;  4LRE A;  4FDJ A;  5K4P A;  1SHN A;  4UPI A;  5HRT A;  3UN5 A;  3M8Z A;  1ELY A;  3MK1 A;  3T02 A;  4LR2 A;  1B8J A;  2ZKT A;  2XRG A;  3WAW A;  1ANJ A;  1E2S P;  4LRC A;  1N2L A;  3DPC A;  3MK2 A;  1KH4 A;  3NKM A;  3WAY A;  2W5S A;  1AJA A;  4MHX A;  1N2K A;  4UPK A;  1FSU A;  2VQR A;  2W5T A;  2ANH A;  1EW9 A;  2D1G A;  1ALI A;  5GRR A; 
#chains in the Genus database with same CATH topology
 1AJD A;  4LQY A;  1E3C P;  1KH5 A;  3UNY A;  1ELZ A;  5LRM A;  1AUK A;  4FDI A;  3BDG B;  2GSU A;  2X98 A;  5C66 A;  2W5W A;  4ZG7 A;  1KHL A;  3WAX A;  3IGZ B;  5L0K A;  4UPH A;  3ED4 A;  5LQQ A;  5L0B A;  1HJK A;  4CYR A;  5L0E A;  3T01 A;  1HQA A;  1URA A;  1EW2 A;  3IGY B;  4MIV A;  1ALJ A;  3OT9 A;  4GTW A;  3BDF A;  1E33 P;  3M7V A;  2G9Y A;  2W8S A;  3MK0 A;  3SZY A;  3CMR A;  2QZU A;  5AJ9 A;  3UN2 A;  3TG0 A;  2GA3 A;  4NWX A;  4CXU A;  1ZEF A;  3NKN A;  4TN0 A;  1KHN A;  1ANI A;  1HDH A;  1K7H A;  4LR7 A;  3T00 A;  3IDD A;  3SZZ A;  2GSO A;  3WAV A;  1AJC A;  3WBH A;  5LIA A;  4GTX A;  1EI6 A;  4CXS A;  4UOP A;  3BDG A;  5KXA A;  1ELX A;  4UOR A;  1KHJ A;  3UO0 A;  1ALK A;  1ZEB A;  5DLW A;  2GLQ A;  4GTY A;  3A52 A;  1AJB A;  2W5Q A;  3M8Y A;  3NKO A;  4KM4 A;  4N7T A;  3LXQ A;  5GOV A;  1Y6V A;  1EW8 A;  2GSN A;  2W5R A;  4YR1 A;  5LRN A;  4LRB A;  1Y7A A;  5EGE A;  2IUC A;  3NVL A;  3KD8 A;  2IUC B;  1ED8 A;  3E2D A;  4ZGA A;  4CYS A;  5TJ3 A;  4LRF A;  4NWJ A;  4ZG6 A;  5INH A;  1O99 A;  4UPL A;  3TWZ A;  4GTZ A;  1P49 A;  4CXK A;  4LR9 A;  3DYC A;  2IFY A;  2W8D A;  4KAV A;  5DLV A;  4LRA A;  2RH6 A;  4LRD A;  1URB A;  1SHQ A;  5IJQ A;  3NKP A;  4KJG A;  4MY4 A;  3B5Q A;  1EQJ A;  1KH9 A;  3M8W A;  2XR9 A;  1E1Z P;  3Q3Q A;  4LR8 A;  1KH7 A;  2W5X A;  3NKR A;  4QAX A;  2W5V A;  4KAY A;  3BDH A;  5IJS A;  3NKQ A;  1KHK A;  1ED9 A;  4KJD A;  5EGH A;  1ZED A;  5DLT A;  1O98 A;  4B56 A;  1EJJ A;  3TX0 A;  4ZG9 A;  4UOO A;  3UN3 A;  1ALH A;  4LRE A;  4FDJ A;  5K4P A;  1SHN A;  4UPI A;  5HRT A;  3UN5 A;  3M8Z A;  1ELY A;  3MK1 A;  3T02 A;  4LR2 A;  1B8J A;  2ZKT A;  2XRG A;  3WAW A;  1ANJ A;  1E2S P;  4LRC A;  1N2L A;  3DPC A;  3MK2 A;  1KH4 A;  3NKM A;  3WAY A;  2W5S A;  1AJA A;  4MHX A;  1N2K A;  4UPK A;  1FSU A;  2VQR A;  2W5T A;  2ANH A;  1EW9 A;  2D1G A;  1ALI A;  5GRR A; 
#chains in the Genus database with same CATH homology
 1AJD A;  4LQY A;  1E3C P;  1KH5 A;  3UNY A;  1ELZ A;  5LRM A;  1AUK A;  4FDI A;  3BDG B;  2GSU A;  2X98 A;  5C66 A;  2W5W A;  4ZG7 A;  1KHL A;  3WAX A;  3IGZ B;  5L0K A;  4UPH A;  3ED4 A;  5LQQ A;  5L0B A;  1HJK A;  4CYR A;  5L0E A;  3T01 A;  1HQA A;  1URA A;  1EW2 A;  3IGY B;  4MIV A;  1ALJ A;  3OT9 A;  4GTW A;  3BDF A;  1E33 P;  3M7V A;  2G9Y A;  2W8S A;  3MK0 A;  3SZY A;  3CMR A;  2QZU A;  5AJ9 A;  3UN2 A;  3TG0 A;  2GA3 A;  4NWX A;  4CXU A;  1ZEF A;  3NKN A;  4TN0 A;  1KHN A;  1ANI A;  1HDH A;  1K7H A;  4LR7 A;  3T00 A;  3IDD A;  3SZZ A;  2GSO A;  3WAV A;  1AJC A;  3WBH A;  5LIA A;  4GTX A;  1EI6 A;  4CXS A;  4UOP A;  3BDG A;  5KXA A;  1ELX A;  4UOR A;  1KHJ A;  3UO0 A;  1ALK A;  1ZEB A;  5DLW A;  2GLQ A;  4GTY A;  3A52 A;  1AJB A;  2W5Q A;  3M8Y A;  3NKO A;  4KM4 A;  4N7T A;  3LXQ A;  5GOV A;  1Y6V A;  1EW8 A;  2GSN A;  2W5R A;  4YR1 A;  5LRN A;  4LRB A;  1Y7A A;  5EGE A;  2IUC A;  3NVL A;  3KD8 A;  2IUC B;  1ED8 A;  3E2D A;  4ZGA A;  4CYS A;  5TJ3 A;  4LRF A;  4NWJ A;  4ZG6 A;  5INH A;  1O99 A;  4UPL A;  3TWZ A;  4GTZ A;  1P49 A;  4CXK A;  4LR9 A;  3DYC A;  2IFY A;  2W8D A;  4KAV A;  5DLV A;  4LRA A;  2RH6 A;  4LRD A;  1URB A;  1SHQ A;  5IJQ A;  3NKP A;  4KJG A;  4MY4 A;  3B5Q A;  1EQJ A;  1KH9 A;  3M8W A;  2XR9 A;  1E1Z P;  3Q3Q A;  4LR8 A;  1KH7 A;  2W5X A;  3NKR A;  4QAX A;  2W5V A;  4KAY A;  3BDH A;  5IJS A;  3NKQ A;  1KHK A;  1ED9 A;  4KJD A;  5EGH A;  1ZED A;  5DLT A;  1O98 A;  4B56 A;  1EJJ A;  3TX0 A;  4ZG9 A;  4UOO A;  3UN3 A;  1ALH A;  4LRE A;  4FDJ A;  5K4P A;  1SHN A;  4UPI A;  5HRT A;  3UN5 A;  3M8Z A;  1ELY A;  3MK1 A;  3T02 A;  4LR2 A;  1B8J A;  2ZKT A;  2XRG A;  3WAW A;  1ANJ A;  1E2S P;  4LRC A;  1N2L A;  3DPC A;  3MK2 A;  1KH4 A;  3NKM A;  3WAY A;  2W5S A;  1AJA A;  4MHX A;  1N2K A;  4UPK A;  1FSU A;  2VQR A;  2W5T A;  2ANH A;  1EW9 A;  2D1G A;  1ALI A;  5GRR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...