3DPCA

Structure of e.coli alkaline phosphatase mutant in complex with a phosphorylated peptide
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
Knots found
sequence length
449
structure length
449
Chain Sequence
PEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDLAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
pubmed doi rcsb
molecule keywords Alkaline phosphatase
molecule tags Hydrolase
source organism Escherichia coli
total genus 147
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2008-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3dpcA00
4GTZA 4TN0A 2IFYA 3ED4A 4GTYA 4LREA 5DLWA 4NWJA 1EW8A 4GTXA 5EGHA 1ALKA 4LR7A 2GLQA 5GRRA 4KM4A 2GA3A 2ANHA 1O98A 3LXQA 1KHJA 3Q3QA 1ED8A 1ALIA 5L0KA 2D1GA 3SZZA 1Y7AA 3UN3A 4LR8A 5L0EA 5LIAA 1ANJA 1Y6VA 4MIVA 5C66A 1ED9A 1E2SP 4UOPA 1B8JA 3A52A 4ZG6A 5DLTA 1N2KA 3OT9A 1KHNA 5L0BA 3T02A 3WAXA 4ZG7A 1ELXA 1ZEDA 3WAYA 5K4PA 1AUKA 1EW2A 1N2LA 3T00A 4KAYA 3IGZB 3IGYB 2W5XA 3NKOA 2IUCB 4ZG9A 3TG0A 5INHA 5HRTA 4B56A 2G9YA 1E3CP 1ALHA 3WAWA 4LRCA 3T01A 3IDDA 1KH5A 2ZKTA 5AJ9A 4N7TA 4CXKA 3BDHA 4KJGA 3WAVA 1FSUA 1ELZA 3NKMA 3BDGA 3M7VA 4LRBA 1KH9A 4LR2A 3M8ZA 3NKNA 1SHNA 3DPCA 3M8YA 4LQYA 1URAA 5LRNA 5LQQA 2RH6A 1EI6A 1ZEBA 1E33P 4FDIA 1O99A 3UN5A 2GSNA 4UOOA 2W8DA 4UORA 5KXAA 3BDFA 4QAXA 2XR9A 4CYSA 4KJDA 1AJCA 5IJQA 2W5RA 4LRAA 4MY4A 2QZUA 1KHLA 4FDJA 4CXUA 1EJJA 1HJKA 3MK1A 3KD8A 4KAVA 1EW9A 1KHKA 3NKQA 4NWXA 2W5SA 4UPIA 3CMRA 4CYRA 1AJBA 1ALJA 1ELYA 1KH4A 1KH7A 1HDHA 4YR1A 3TX0A 1EQJA 2W8SA 4ZGAA 1K7HA 2VQRA 1AJDA 1ZEFA 3NVLA 3UNYA 2W5WA 4UPLA 1AJAA 3MK2A 2GSOA 4GTWA 3SZYA 3WBHA 1URBA 3B5QA 1SHQA 3UO0A 3MK0A 3NKPA 4LRFA 5LRMA 4UPHA 1E1ZP 2W5TA 3E2DA 2W5QA 4LRDA 3TWZA 1HQAA 4CXSA 4UPKA 3BDGB 4MHXA 3UN2A 2X98A 5DLVA 2IUCA 5GOVA 1ANIA 3DYCA 5IJSA 4LR9A 2W5VA 2GSUA 3NKRA 5TJ3A 5EGEA 2XRGA 1P49A 3M8WA
chains in the Genus database with same CATH superfamily
4GTZA 4TN0A 2IFYA 3ED4A 4GTYA 4LREA 5DLWA 4NWJA 1EW8A 4GTXA 5EGHA 1ALKA 4LR7A 2GLQA 5GRRA 4KM4A 2GA3A 2ANHA 1O98A 3LXQA 1KHJA 3Q3QA 1ED8A 1ALIA 5L0KA 2D1GA 3SZZA 1Y7AA 3UN3A 4LR8A 5L0EA 5LIAA 1ANJA 1Y6VA 4MIVA 5C66A 1ED9A 1E2SP 4UOPA 1B8JA 3A52A 4ZG6A 5DLTA 1N2KA 3OT9A 1KHNA 5L0BA 3T02A 3WAXA 4ZG7A 1ELXA 1ZEDA 3WAYA 5K4PA 1AUKA 1EW2A 1N2LA 3T00A 4KAYA 3IGZB 3IGYB 2W5XA 3NKOA 2IUCB 4ZG9A 3TG0A 5INHA 5HRTA 4B56A 2G9YA 1E3CP 1ALHA 3WAWA 4LRCA 3T01A 3IDDA 1KH5A 2ZKTA 5AJ9A 4N7TA 4CXKA 3BDHA 4KJGA 3WAVA 1FSUA 1ELZA 3NKMA 3BDGA 3M7VA 4LRBA 1KH9A 4LR2A 3M8ZA 3NKNA 1SHNA 3DPCA 3M8YA 4LQYA 1URAA 5LRNA 5LQQA 2RH6A 1EI6A 1ZEBA 1E33P 4FDIA 1O99A 3UN5A 2GSNA 4UOOA 2W8DA 4UORA 5KXAA 3BDFA 4QAXA 2XR9A 4CYSA 4KJDA 1AJCA 5IJQA 2W5RA 4LRAA 4MY4A 2QZUA 1KHLA 4FDJA 4CXUA 1EJJA 1HJKA 3MK1A 3KD8A 4KAVA 1EW9A 1KHKA 3NKQA 4NWXA 2W5SA 4UPIA 3CMRA 4CYRA 1AJBA 1ALJA 1ELYA 1KH4A 1KH7A 1HDHA 4YR1A 3TX0A 1EQJA 2W8SA 4ZGAA 1K7HA 2VQRA 1AJDA 1ZEFA 3NVLA 3UNYA 2W5WA 4UPLA 1AJAA 3MK2A 2GSOA 4GTWA 3SZYA 3WBHA 1URBA 3B5QA 1SHQA 3UO0A 3MK0A 3NKPA 4LRFA 5LRMA 4UPHA 1E1ZP 2W5TA 3E2DA 2W5QA 4LRDA 3TWZA 1HQAA 4CXSA 4UPKA 3BDGB 4MHXA 3UN2A 2X98A 5DLVA 2IUCA 5GOVA 1ANIA 3DYCA 5IJSA 4LR9A 2W5VA 2GSUA 3NKRA 5TJ3A 5EGEA 2XRGA 1P49A 3M8WA
chains in the Genus database with same CATH topology
4GTZA 4TN0A 2IFYA 3ED4A 4GTYA 4LREA 5DLWA 4NWJA 1EW8A 4GTXA 5EGHA 1ALKA 4LR7A 2GLQA 5GRRA 4KM4A 2GA3A 2ANHA 1O98A 3LXQA 1KHJA 3Q3QA 1ED8A 1ALIA 5L0KA 2D1GA 3SZZA 1Y7AA 3UN3A 4LR8A 5L0EA 5LIAA 1ANJA 1Y6VA 4MIVA 5C66A 1ED9A 1E2SP 4UOPA 1B8JA 3A52A 4ZG6A 5DLTA 1N2KA 3OT9A 1KHNA 5L0BA 3T02A 3WAXA 4ZG7A 1ELXA 1ZEDA 3WAYA 5K4PA 1AUKA 1EW2A 1N2LA 3T00A 4KAYA 3IGZB 3IGYB 2W5XA 3NKOA 2IUCB 4ZG9A 3TG0A 5INHA 5HRTA 4B56A 2G9YA 1E3CP 1ALHA 3WAWA 4LRCA 3T01A 3IDDA 1KH5A 2ZKTA 5AJ9A 4N7TA 4CXKA 3BDHA 4KJGA 3WAVA 1FSUA 1ELZA 3NKMA 3BDGA 3M7VA 4LRBA 1KH9A 4LR2A 3M8ZA 3NKNA 1SHNA 3DPCA 3M8YA 4LQYA 1URAA 5LRNA 5LQQA 2RH6A 1EI6A 1ZEBA 1E33P 4FDIA 1O99A 3UN5A 2GSNA 4UOOA 2W8DA 4UORA 5KXAA 3BDFA 4QAXA 2XR9A 4CYSA 4KJDA 1AJCA 5IJQA 2W5RA 4LRAA 4MY4A 2QZUA 1KHLA 4FDJA 4CXUA 1EJJA 1HJKA 3MK1A 3KD8A 4KAVA 1EW9A 1KHKA 3NKQA 4NWXA 2W5SA 4UPIA 3CMRA 4CYRA 1AJBA 1ALJA 1ELYA 1KH4A 1KH7A 1HDHA 4YR1A 3TX0A 1EQJA 2W8SA 4ZGAA 1K7HA 2VQRA 1AJDA 1ZEFA 3NVLA 3UNYA 2W5WA 4UPLA 1AJAA 3MK2A 2GSOA 4GTWA 3SZYA 3WBHA 1URBA 3B5QA 1SHQA 3UO0A 3MK0A 3NKPA 4LRFA 5LRMA 4UPHA 1E1ZP 2W5TA 3E2DA 2W5QA 4LRDA 3TWZA 1HQAA 4CXSA 4UPKA 3BDGB 4MHXA 3UN2A 2X98A 5DLVA 2IUCA 5GOVA 1ANIA 3DYCA 5IJSA 4LR9A 2W5VA 2GSUA 3NKRA 5TJ3A 5EGEA 2XRGA 1P49A 3M8WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GTZ A;  4TN0 A;  2IFY A;  3ED4 A;  4GTY A;  4LRE A;  5DLW A;  4NWJ A;  1EW8 A;  4GTX A;  5EGH A;  1ALK A;  4LR7 A;  2GLQ A;  5GRR A;  4KM4 A;  2GA3 A;  2ANH A;  1O98 A;  3LXQ A;  1KHJ A;  3Q3Q A;  1ED8 A;  1ALI A;  5L0K A;  2D1G A;  3SZZ A;  1Y7A A;  3UN3 A;  4LR8 A;  5L0E A;  5LIA A;  1ANJ A;  1Y6V A;  4MIV A;  5C66 A;  1ED9 A;  1E2S P;  4UOP A;  1B8J A;  3A52 A;  4ZG6 A;  5DLT A;  1N2K A;  3OT9 A;  1KHN A;  5L0B A;  3T02 A;  3WAX A;  4ZG7 A;  1ELX A;  1ZED A;  3WAY A;  5K4P A;  1AUK A;  1EW2 A;  1N2L A;  3T00 A;  4KAY A;  3IGZ B;  3IGY B;  2W5X A;  3NKO A;  2IUC B;  4ZG9 A;  3TG0 A;  5INH A;  5HRT A;  4B56 A;  2G9Y A;  1E3C P;  1ALH A;  3WAW A;  4LRC A;  3T01 A;  3IDD A;  1KH5 A;  2ZKT A;  5AJ9 A;  4N7T A;  4CXK A;  3BDH A;  4KJG A;  3WAV A;  1FSU A;  1ELZ A;  3NKM A;  3BDG A;  3M7V A;  4LRB A;  1KH9 A;  4LR2 A;  3M8Z A;  3NKN A;  1SHN A;  3DPC A;  3M8Y A;  4LQY A;  1URA A;  5LRN A;  5LQQ A;  2RH6 A;  1EI6 A;  1ZEB A;  1E33 P;  4FDI A;  1O99 A;  3UN5 A;  2GSN A;  4UOO A;  2W8D A;  4UOR A;  5KXA A;  3BDF A;  4QAX A;  2XR9 A;  4CYS A;  4KJD A;  1AJC A;  5IJQ A;  2W5R A;  4LRA A;  4MY4 A;  2QZU A;  1KHL A;  4FDJ A;  4CXU A;  1EJJ A;  1HJK A;  3MK1 A;  3KD8 A;  4KAV A;  1EW9 A;  1KHK A;  3NKQ A;  4NWX A;  2W5S A;  4UPI A;  3CMR A;  4CYR A;  1AJB A;  1ALJ A;  1ELY A;  1KH4 A;  1KH7 A;  1HDH A;  4YR1 A;  3TX0 A;  1EQJ A;  2W8S A;  4ZGA A;  1K7H A;  2VQR A;  1AJD A;  1ZEF A;  3NVL A;  3UNY A;  2W5W A;  4UPL A;  1AJA A;  3MK2 A;  2GSO A;  4GTW A;  3SZY A;  3WBH A;  1URB A;  3B5Q A;  1SHQ A;  3UO0 A;  3MK0 A;  3NKP A;  4LRF A;  5LRM A;  4UPH A;  1E1Z P;  2W5T A;  3E2D A;  2W5Q A;  4LRD A;  3TWZ A;  1HQA A;  4CXS A;  4UPK A;  3BDG B;  4MHX A;  3UN2 A;  2X98 A;  5DLV A;  2IUC A;  5GOV A;  1ANI A;  3DYC A;  5IJS A;  4LR9 A;  2W5V A;  2GSU A;  3NKR A;  5TJ3 A;  5EGE A;  2XRG A;  1P49 A;  3M8W A; 
#chains in the Genus database with same CATH topology
 4GTZ A;  4TN0 A;  2IFY A;  3ED4 A;  4GTY A;  4LRE A;  5DLW A;  4NWJ A;  1EW8 A;  4GTX A;  5EGH A;  1ALK A;  4LR7 A;  2GLQ A;  5GRR A;  4KM4 A;  2GA3 A;  2ANH A;  1O98 A;  3LXQ A;  1KHJ A;  3Q3Q A;  1ED8 A;  1ALI A;  5L0K A;  2D1G A;  3SZZ A;  1Y7A A;  3UN3 A;  4LR8 A;  5L0E A;  5LIA A;  1ANJ A;  1Y6V A;  4MIV A;  5C66 A;  1ED9 A;  1E2S P;  4UOP A;  1B8J A;  3A52 A;  4ZG6 A;  5DLT A;  1N2K A;  3OT9 A;  1KHN A;  5L0B A;  3T02 A;  3WAX A;  4ZG7 A;  1ELX A;  1ZED A;  3WAY A;  5K4P A;  1AUK A;  1EW2 A;  1N2L A;  3T00 A;  4KAY A;  3IGZ B;  3IGY B;  2W5X A;  3NKO A;  2IUC B;  4ZG9 A;  3TG0 A;  5INH A;  5HRT A;  4B56 A;  2G9Y A;  1E3C P;  1ALH A;  3WAW A;  4LRC A;  3T01 A;  3IDD A;  1KH5 A;  2ZKT A;  5AJ9 A;  4N7T A;  4CXK A;  3BDH A;  4KJG A;  3WAV A;  1FSU A;  1ELZ A;  3NKM A;  3BDG A;  3M7V A;  4LRB A;  1KH9 A;  4LR2 A;  3M8Z A;  3NKN A;  1SHN A;  3DPC A;  3M8Y A;  4LQY A;  1URA A;  5LRN A;  5LQQ A;  2RH6 A;  1EI6 A;  1ZEB A;  1E33 P;  4FDI A;  1O99 A;  3UN5 A;  2GSN A;  4UOO A;  2W8D A;  4UOR A;  5KXA A;  3BDF A;  4QAX A;  2XR9 A;  4CYS A;  4KJD A;  1AJC A;  5IJQ A;  2W5R A;  4LRA A;  4MY4 A;  2QZU A;  1KHL A;  4FDJ A;  4CXU A;  1EJJ A;  1HJK A;  3MK1 A;  3KD8 A;  4KAV A;  1EW9 A;  1KHK A;  3NKQ A;  4NWX A;  2W5S A;  4UPI A;  3CMR A;  4CYR A;  1AJB A;  1ALJ A;  1ELY A;  1KH4 A;  1KH7 A;  1HDH A;  4YR1 A;  3TX0 A;  1EQJ A;  2W8S A;  4ZGA A;  1K7H A;  2VQR A;  1AJD A;  1ZEF A;  3NVL A;  3UNY A;  2W5W A;  4UPL A;  1AJA A;  3MK2 A;  2GSO A;  4GTW A;  3SZY A;  3WBH A;  1URB A;  3B5Q A;  1SHQ A;  3UO0 A;  3MK0 A;  3NKP A;  4LRF A;  5LRM A;  4UPH A;  1E1Z P;  2W5T A;  3E2D A;  2W5Q A;  4LRD A;  3TWZ A;  1HQA A;  4CXS A;  4UPK A;  3BDG B;  4MHX A;  3UN2 A;  2X98 A;  5DLV A;  2IUC A;  5GOV A;  1ANI A;  3DYC A;  5IJS A;  4LR9 A;  2W5V A;  2GSU A;  3NKR A;  5TJ3 A;  5EGE A;  2XRG A;  1P49 A;  3M8W A; 
#chains in the Genus database with same CATH homology
 4GTZ A;  4TN0 A;  2IFY A;  3ED4 A;  4GTY A;  4LRE A;  5DLW A;  4NWJ A;  1EW8 A;  4GTX A;  5EGH A;  1ALK A;  4LR7 A;  2GLQ A;  5GRR A;  4KM4 A;  2GA3 A;  2ANH A;  1O98 A;  3LXQ A;  1KHJ A;  3Q3Q A;  1ED8 A;  1ALI A;  5L0K A;  2D1G A;  3SZZ A;  1Y7A A;  3UN3 A;  4LR8 A;  5L0E A;  5LIA A;  1ANJ A;  1Y6V A;  4MIV A;  5C66 A;  1ED9 A;  1E2S P;  4UOP A;  1B8J A;  3A52 A;  4ZG6 A;  5DLT A;  1N2K A;  3OT9 A;  1KHN A;  5L0B A;  3T02 A;  3WAX A;  4ZG7 A;  1ELX A;  1ZED A;  3WAY A;  5K4P A;  1AUK A;  1EW2 A;  1N2L A;  3T00 A;  4KAY A;  3IGZ B;  3IGY B;  2W5X A;  3NKO A;  2IUC B;  4ZG9 A;  3TG0 A;  5INH A;  5HRT A;  4B56 A;  2G9Y A;  1E3C P;  1ALH A;  3WAW A;  4LRC A;  3T01 A;  3IDD A;  1KH5 A;  2ZKT A;  5AJ9 A;  4N7T A;  4CXK A;  3BDH A;  4KJG A;  3WAV A;  1FSU A;  1ELZ A;  3NKM A;  3BDG A;  3M7V A;  4LRB A;  1KH9 A;  4LR2 A;  3M8Z A;  3NKN A;  1SHN A;  3DPC A;  3M8Y A;  4LQY A;  1URA A;  5LRN A;  5LQQ A;  2RH6 A;  1EI6 A;  1ZEB A;  1E33 P;  4FDI A;  1O99 A;  3UN5 A;  2GSN A;  4UOO A;  2W8D A;  4UOR A;  5KXA A;  3BDF A;  4QAX A;  2XR9 A;  4CYS A;  4KJD A;  1AJC A;  5IJQ A;  2W5R A;  4LRA A;  4MY4 A;  2QZU A;  1KHL A;  4FDJ A;  4CXU A;  1EJJ A;  1HJK A;  3MK1 A;  3KD8 A;  4KAV A;  1EW9 A;  1KHK A;  3NKQ A;  4NWX A;  2W5S A;  4UPI A;  3CMR A;  4CYR A;  1AJB A;  1ALJ A;  1ELY A;  1KH4 A;  1KH7 A;  1HDH A;  4YR1 A;  3TX0 A;  1EQJ A;  2W8S A;  4ZGA A;  1K7H A;  2VQR A;  1AJD A;  1ZEF A;  3NVL A;  3UNY A;  2W5W A;  4UPL A;  1AJA A;  3MK2 A;  2GSO A;  4GTW A;  3SZY A;  3WBH A;  1URB A;  3B5Q A;  1SHQ A;  3UO0 A;  3MK0 A;  3NKP A;  4LRF A;  5LRM A;  4UPH A;  1E1Z P;  2W5T A;  3E2D A;  2W5Q A;  4LRD A;  3TWZ A;  1HQA A;  4CXS A;  4UPK A;  3BDG B;  4MHX A;  3UN2 A;  2X98 A;  5DLV A;  2IUC A;  5GOV A;  1ANI A;  3DYC A;  5IJS A;  4LR9 A;  2W5V A;  2GSU A;  3NKR A;  5TJ3 A;  5EGE A;  2XRG A;  1P49 A;  3M8W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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