4MY4A

Crystal structure of phosphoglycerate mutase from staphylococcus aureus.
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
Knots found
sequence length
503
structure length
503
Chain Sequence
KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism
pubmed doi rcsb
source organism Staphylococcus aureus subsp. aureus
molecule tags Isomerase
molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
total genus 192
structure length 503
sequence length 503
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2013-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4my4A01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 4my4A02
3M8YA 3LXQA 1EW2A 4CXUA 1EW8A 2GA3A 3NKQA 3UN2A 4GTZA 2GSOA 2GSUA 4LRFA 5LRMA 1KHKA 3TWZA 5DLWA 2D1GA 1KH5A 1O98A 5C66A 3E2DA 3BDGB 3IGYB 1Y6VA 1K7HA 3M8ZA 3NKOA 2W5QA 1O99A 3BDGA 4UPLA 1ANJA 1EJJA 1HDHA 1P49A 5LRNA 5GOVA 2ANHA 2G9YA 3MK2A 2W5VA 3A52A 4LRBA 4NWXA 4GTYA 4ZG6A 4KM4A 3DYCA 4LR7A 2GLQA 3IDDA 1ED9A 5AJ9A 1KH9A 4LQYA 4ZG9A 3NKRA 4GTXA 3NKNA 3MK1A 2W5TA 3SZZA 3BDHA 1ELXA 1HQAA 3BDFA 1HJKA 4KAYA 4UOOA 1URAA 3UNYA 3WAWA 1E3CP 1Y7AA 1FSUA 1E1ZP 1KH4A 2XRGA 4UORA 3T01A 3WAYA 4MY4A 4CXSA 5KXAA 3UO0A 3OT9A 5K4PA 3TG0A 2VQRA 2X98A 2QZUA 5EGEA 4KAVA 1ANIA 1ELZA 2W8SA 5LIAA 5HRTA 2W5WA 5DLTA 3NKMA 4GTWA 4MIVA 1AUKA 1ELYA 1B8JA 2W5SA 3WBHA 1ZEBA 4CYSA 2W8DA 3NKPA 5L0KA 4LR9A 1KHLA 1EI6A 5IJSA 4CXKA 3NVLA 5INHA 1EQJA 5DLVA 2IUCA 1AJAA 5TJ3A 1ALHA 1URBA 1KH7A 3M8WA 1AJDA 1N2KA 5IJQA 4B56A 1ALJA 4LRDA 3UN5A 4N7TA 2W5RA 3WAXA 2IUCB 5GRRA 1AJBA 4CYRA 3KD8A 3SZYA 5LQQA 4QAXA 4UPHA 3T02A 2ZKTA 4NWJA 3Q3QA 3UN3A 3CMRA 1SHNA 1ALKA 1SHQA 4FDIA 2IFYA 4LREA 4UPKA 3M7VA 2GSNA 4LR2A 3WAVA 2XR9A 4TN0A 1ZEDA 5L0BA 3ED4A 2W5XA 3T00A 5L0EA 2RH6A 4LRAA 3IGZB 3TX0A 1KHNA 4UOPA 4ZG7A 4ZGAA 4LRCA 1KHJA 1AJCA 4MHXA 1E2SP 4YR1A 3DPCA 4FDJA 4KJGA 5EGHA 1ALIA 4KJDA 1ZEFA 3B5QA 4UPIA 3MK0A 1EW9A 1ED8A 1E33P 4LR8A 1N2LA
chains in the Genus database with same CATH superfamily
3M8YA 3LXQA 1EW2A 4CXUA 1EW8A 2GA3A 3NKQA 3UN2A 4GTZA 2GSOA 2GSUA 4LRFA 5LRMA 1KHKA 3TWZA 5DLWA 2D1GA 1KH5A 1O98A 5C66A 3E2DA 3BDGB 3IGYB 1Y6VA 1K7HA 3M8ZA 3NKOA 2W5QA 1O99A 3BDGA 4UPLA 1ANJA 1EJJA 1HDHA 1P49A 5LRNA 5GOVA 2ANHA 2G9YA 3MK2A 2W5VA 3A52A 4LRBA 4NWXA 4GTYA 4ZG6A 4KM4A 3DYCA 4LR7A 2GLQA 3IDDA 1ED9A 5AJ9A 1KH9A 4LQYA 4ZG9A 3NKRA 4GTXA 3NKNA 3MK1A 2W5TA 3SZZA 3BDHA 1ELXA 1HQAA 3BDFA 1HJKA 4KAYA 4UOOA 1URAA 3UNYA 3WAWA 1E3CP 1Y7AA 1FSUA 1E1ZP 1KH4A 2XRGA 4UORA 3T01A 3WAYA 4MY4A 4CXSA 5KXAA 3UO0A 3OT9A 5K4PA 3TG0A 2VQRA 2X98A 2QZUA 5EGEA 4KAVA 1ANIA 1ELZA 2W8SA 5LIAA 5HRTA 2W5WA 5DLTA 3NKMA 4GTWA 4MIVA 1AUKA 1ELYA 1B8JA 2W5SA 3WBHA 1ZEBA 4CYSA 2W8DA 3NKPA 5L0KA 4LR9A 1KHLA 1EI6A 5IJSA 4CXKA 3NVLA 5INHA 1EQJA 5DLVA 2IUCA 1AJAA 5TJ3A 1ALHA 1URBA 1KH7A 3M8WA 1AJDA 1N2KA 5IJQA 4B56A 1ALJA 4LRDA 3UN5A 4N7TA 2W5RA 3WAXA 2IUCB 5GRRA 1AJBA 4CYRA 3KD8A 3SZYA 5LQQA 4QAXA 4UPHA 3T02A 2ZKTA 4NWJA 3Q3QA 3UN3A 3CMRA 1SHNA 1ALKA 1SHQA 4FDIA 2IFYA 4LREA 4UPKA 3M7VA 2GSNA 4LR2A 3WAVA 2XR9A 4TN0A 1ZEDA 5L0BA 3ED4A 2W5XA 3T00A 5L0EA 2RH6A 4LRAA 3IGZB 3TX0A 1KHNA 4UOPA 4ZG7A 4ZGAA 4LRCA 1KHJA 1AJCA 4MHXA 1E2SP 4YR1A 3DPCA 4FDJA 4KJGA 5EGHA 1ALIA 4KJDA 1ZEFA 3B5QA 4UPIA 3MK0A 1EW9A 1ED8A 1E33P 4LR8A 1N2LA
chains in the Genus database with same CATH topology
3M8YA 3LXQA 1EW2A 4CXUA 1EW8A 2GA3A 3NKQA 3UN2A 4GTZA 2GSOA 2GSUA 4LRFA 5LRMA 1KHKA 3TWZA 5DLWA 2D1GA 1KH5A 1O98A 5C66A 3E2DA 3BDGB 3IGYB 1Y6VA 1K7HA 3M8ZA 3NKOA 2W5QA 1O99A 3BDGA 4UPLA 1ANJA 1EJJA 1HDHA 1P49A 5LRNA 5GOVA 2ANHA 2G9YA 3MK2A 2W5VA 3A52A 4LRBA 4NWXA 4GTYA 4ZG6A 4KM4A 3DYCA 4LR7A 2GLQA 3IDDA 1ED9A 5AJ9A 1KH9A 4LQYA 4ZG9A 3NKRA 4GTXA 3NKNA 3MK1A 2W5TA 3SZZA 3BDHA 1ELXA 1HQAA 3BDFA 1HJKA 4KAYA 4UOOA 1URAA 3UNYA 3WAWA 1E3CP 1Y7AA 1FSUA 1E1ZP 1KH4A 2XRGA 4UORA 3T01A 3WAYA 4MY4A 4CXSA 5KXAA 3UO0A 3OT9A 5K4PA 3TG0A 2VQRA 2X98A 2QZUA 5EGEA 4KAVA 1ANIA 1ELZA 2W8SA 5LIAA 5HRTA 2W5WA 5DLTA 3NKMA 4GTWA 4MIVA 1AUKA 1ELYA 1B8JA 2W5SA 3WBHA 1ZEBA 4CYSA 2W8DA 3NKPA 5L0KA 4LR9A 1KHLA 1EI6A 5IJSA 4CXKA 3NVLA 5INHA 1EQJA 5DLVA 2IUCA 1AJAA 5TJ3A 1ALHA 1URBA 1KH7A 3M8WA 1AJDA 1N2KA 5IJQA 4B56A 1ALJA 4LRDA 3UN5A 4N7TA 2W5RA 3WAXA 2IUCB 5GRRA 1AJBA 4CYRA 3KD8A 3SZYA 5LQQA 4QAXA 4UPHA 3T02A 2ZKTA 4NWJA 3Q3QA 3UN3A 3CMRA 1SHNA 1ALKA 1SHQA 4FDIA 2IFYA 4LREA 4UPKA 3M7VA 2GSNA 4LR2A 3WAVA 2XR9A 4TN0A 1ZEDA 5L0BA 3ED4A 2W5XA 3T00A 5L0EA 2RH6A 4LRAA 3IGZB 3TX0A 1KHNA 4UOPA 4ZG7A 4ZGAA 4LRCA 1KHJA 1AJCA 4MHXA 1E2SP 4YR1A 3DPCA 4FDJA 4KJGA 5EGHA 1ALIA 4KJDA 1ZEFA 3B5QA 4UPIA 3MK0A 1EW9A 1ED8A 1E33P 4LR8A 1N2LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M8Y A;  3LXQ A;  1EW2 A;  4CXU A;  1EW8 A;  2GA3 A;  3NKQ A;  3UN2 A;  4GTZ A;  2GSO A;  2GSU A;  4LRF A;  5LRM A;  1KHK A;  3TWZ A;  5DLW A;  2D1G A;  1KH5 A;  1O98 A;  5C66 A;  3E2D A;  3BDG B;  3IGY B;  1Y6V A;  1K7H A;  3M8Z A;  3NKO A;  2W5Q A;  1O99 A;  3BDG A;  4UPL A;  1ANJ A;  1EJJ A;  1HDH A;  1P49 A;  5LRN A;  5GOV A;  2ANH A;  2G9Y A;  3MK2 A;  2W5V A;  3A52 A;  4LRB A;  4NWX A;  4GTY A;  4ZG6 A;  4KM4 A;  3DYC A;  4LR7 A;  2GLQ A;  3IDD A;  1ED9 A;  5AJ9 A;  1KH9 A;  4LQY A;  4ZG9 A;  3NKR A;  4GTX A;  3NKN A;  3MK1 A;  2W5T A;  3SZZ A;  3BDH A;  1ELX A;  1HQA A;  3BDF A;  1HJK A;  4KAY A;  4UOO A;  1URA A;  3UNY A;  3WAW A;  1E3C P;  1Y7A A;  1FSU A;  1E1Z P;  1KH4 A;  2XRG A;  4UOR A;  3T01 A;  3WAY A;  4MY4 A;  4CXS A;  5KXA A;  3UO0 A;  3OT9 A;  5K4P A;  3TG0 A;  2VQR A;  2X98 A;  2QZU A;  5EGE A;  4KAV A;  1ANI A;  1ELZ A;  2W8S A;  5LIA A;  5HRT A;  2W5W A;  5DLT A;  3NKM A;  4GTW A;  4MIV A;  1AUK A;  1ELY A;  1B8J A;  2W5S A;  3WBH A;  1ZEB A;  4CYS A;  2W8D A;  3NKP A;  5L0K A;  4LR9 A;  1KHL A;  1EI6 A;  5IJS A;  4CXK A;  3NVL A;  5INH A;  1EQJ A;  5DLV A;  2IUC A;  1AJA A;  5TJ3 A;  1ALH A;  1URB A;  1KH7 A;  3M8W A;  1AJD A;  1N2K A;  5IJQ A;  4B56 A;  1ALJ A;  4LRD A;  3UN5 A;  4N7T A;  2W5R A;  3WAX A;  2IUC B;  5GRR A;  1AJB A;  4CYR A;  3KD8 A;  3SZY A;  5LQQ A;  4QAX A;  4UPH A;  3T02 A;  2ZKT A;  4NWJ A;  3Q3Q A;  3UN3 A;  3CMR A;  1SHN A;  1ALK A;  1SHQ A;  4FDI A;  2IFY A;  4LRE A;  4UPK A;  3M7V A;  2GSN A;  4LR2 A;  3WAV A;  2XR9 A;  4TN0 A;  1ZED A;  5L0B A;  3ED4 A;  2W5X A;  3T00 A;  5L0E A;  2RH6 A;  4LRA A;  3IGZ B;  3TX0 A;  1KHN A;  4UOP A;  4ZG7 A;  4ZGA A;  4LRC A;  1KHJ A;  1AJC A;  4MHX A;  1E2S P;  4YR1 A;  3DPC A;  4FDJ A;  4KJG A;  5EGH A;  1ALI A;  4KJD A;  1ZEF A;  3B5Q A;  4UPI A;  3MK0 A;  1EW9 A;  1ED8 A;  1E33 P;  4LR8 A;  1N2L A; 
#chains in the Genus database with same CATH topology
 3M8Y A;  3LXQ A;  1EW2 A;  4CXU A;  1EW8 A;  2GA3 A;  3NKQ A;  3UN2 A;  4GTZ A;  2GSO A;  2GSU A;  4LRF A;  5LRM A;  1KHK A;  3TWZ A;  5DLW A;  2D1G A;  1KH5 A;  1O98 A;  5C66 A;  3E2D A;  3BDG B;  3IGY B;  1Y6V A;  1K7H A;  3M8Z A;  3NKO A;  2W5Q A;  1O99 A;  3BDG A;  4UPL A;  1ANJ A;  1EJJ A;  1HDH A;  1P49 A;  5LRN A;  5GOV A;  2ANH A;  2G9Y A;  3MK2 A;  2W5V A;  3A52 A;  4LRB A;  4NWX A;  4GTY A;  4ZG6 A;  4KM4 A;  3DYC A;  4LR7 A;  2GLQ A;  3IDD A;  1ED9 A;  5AJ9 A;  1KH9 A;  4LQY A;  4ZG9 A;  3NKR A;  4GTX A;  3NKN A;  3MK1 A;  2W5T A;  3SZZ A;  3BDH A;  1ELX A;  1HQA A;  3BDF A;  1HJK A;  4KAY A;  4UOO A;  1URA A;  3UNY A;  3WAW A;  1E3C P;  1Y7A A;  1FSU A;  1E1Z P;  1KH4 A;  2XRG A;  4UOR A;  3T01 A;  3WAY A;  4MY4 A;  4CXS A;  5KXA A;  3UO0 A;  3OT9 A;  5K4P A;  3TG0 A;  2VQR A;  2X98 A;  2QZU A;  5EGE A;  4KAV A;  1ANI A;  1ELZ A;  2W8S A;  5LIA A;  5HRT A;  2W5W A;  5DLT A;  3NKM A;  4GTW A;  4MIV A;  1AUK A;  1ELY A;  1B8J A;  2W5S A;  3WBH A;  1ZEB A;  4CYS A;  2W8D A;  3NKP A;  5L0K A;  4LR9 A;  1KHL A;  1EI6 A;  5IJS A;  4CXK A;  3NVL A;  5INH A;  1EQJ A;  5DLV A;  2IUC A;  1AJA A;  5TJ3 A;  1ALH A;  1URB A;  1KH7 A;  3M8W A;  1AJD A;  1N2K A;  5IJQ A;  4B56 A;  1ALJ A;  4LRD A;  3UN5 A;  4N7T A;  2W5R A;  3WAX A;  2IUC B;  5GRR A;  1AJB A;  4CYR A;  3KD8 A;  3SZY A;  5LQQ A;  4QAX A;  4UPH A;  3T02 A;  2ZKT A;  4NWJ A;  3Q3Q A;  3UN3 A;  3CMR A;  1SHN A;  1ALK A;  1SHQ A;  4FDI A;  2IFY A;  4LRE A;  4UPK A;  3M7V A;  2GSN A;  4LR2 A;  3WAV A;  2XR9 A;  4TN0 A;  1ZED A;  5L0B A;  3ED4 A;  2W5X A;  3T00 A;  5L0E A;  2RH6 A;  4LRA A;  3IGZ B;  3TX0 A;  1KHN A;  4UOP A;  4ZG7 A;  4ZGA A;  4LRC A;  1KHJ A;  1AJC A;  4MHX A;  1E2S P;  4YR1 A;  3DPC A;  4FDJ A;  4KJG A;  5EGH A;  1ALI A;  4KJD A;  1ZEF A;  3B5Q A;  4UPI A;  3MK0 A;  1EW9 A;  1ED8 A;  1E33 P;  4LR8 A;  1N2L A; 
#chains in the Genus database with same CATH homology
 3M8Y A;  3LXQ A;  1EW2 A;  4CXU A;  1EW8 A;  2GA3 A;  3NKQ A;  3UN2 A;  4GTZ A;  2GSO A;  2GSU A;  4LRF A;  5LRM A;  1KHK A;  3TWZ A;  5DLW A;  2D1G A;  1KH5 A;  1O98 A;  5C66 A;  3E2D A;  3BDG B;  3IGY B;  1Y6V A;  1K7H A;  3M8Z A;  3NKO A;  2W5Q A;  1O99 A;  3BDG A;  4UPL A;  1ANJ A;  1EJJ A;  1HDH A;  1P49 A;  5LRN A;  5GOV A;  2ANH A;  2G9Y A;  3MK2 A;  2W5V A;  3A52 A;  4LRB A;  4NWX A;  4GTY A;  4ZG6 A;  4KM4 A;  3DYC A;  4LR7 A;  2GLQ A;  3IDD A;  1ED9 A;  5AJ9 A;  1KH9 A;  4LQY A;  4ZG9 A;  3NKR A;  4GTX A;  3NKN A;  3MK1 A;  2W5T A;  3SZZ A;  3BDH A;  1ELX A;  1HQA A;  3BDF A;  1HJK A;  4KAY A;  4UOO A;  1URA A;  3UNY A;  3WAW A;  1E3C P;  1Y7A A;  1FSU A;  1E1Z P;  1KH4 A;  2XRG A;  4UOR A;  3T01 A;  3WAY A;  4MY4 A;  4CXS A;  5KXA A;  3UO0 A;  3OT9 A;  5K4P A;  3TG0 A;  2VQR A;  2X98 A;  2QZU A;  5EGE A;  4KAV A;  1ANI A;  1ELZ A;  2W8S A;  5LIA A;  5HRT A;  2W5W A;  5DLT A;  3NKM A;  4GTW A;  4MIV A;  1AUK A;  1ELY A;  1B8J A;  2W5S A;  3WBH A;  1ZEB A;  4CYS A;  2W8D A;  3NKP A;  5L0K A;  4LR9 A;  1KHL A;  1EI6 A;  5IJS A;  4CXK A;  3NVL A;  5INH A;  1EQJ A;  5DLV A;  2IUC A;  1AJA A;  5TJ3 A;  1ALH A;  1URB A;  1KH7 A;  3M8W A;  1AJD A;  1N2K A;  5IJQ A;  4B56 A;  1ALJ A;  4LRD A;  3UN5 A;  4N7T A;  2W5R A;  3WAX A;  2IUC B;  5GRR A;  1AJB A;  4CYR A;  3KD8 A;  3SZY A;  5LQQ A;  4QAX A;  4UPH A;  3T02 A;  2ZKT A;  4NWJ A;  3Q3Q A;  3UN3 A;  3CMR A;  1SHN A;  1ALK A;  1SHQ A;  4FDI A;  2IFY A;  4LRE A;  4UPK A;  3M7V A;  2GSN A;  4LR2 A;  3WAV A;  2XR9 A;  4TN0 A;  1ZED A;  5L0B A;  3ED4 A;  2W5X A;  3T00 A;  5L0E A;  2RH6 A;  4LRA A;  3IGZ B;  3TX0 A;  1KHN A;  4UOP A;  4ZG7 A;  4ZGA A;  4LRC A;  1KHJ A;  1AJC A;  4MHX A;  1E2S P;  4YR1 A;  3DPC A;  4FDJ A;  4KJG A;  5EGH A;  1ALI A;  4KJD A;  1ZEF A;  3B5Q A;  4UPI A;  3MK0 A;  1EW9 A;  1ED8 A;  1E33 P;  4LR8 A;  1N2L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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