1K7HA

Crystal structure of shrimp alkaline phosphatase
Total Genus 188
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
188
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIANTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSATHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords ALKALINE PHOSPHATASE
publication title The 1.9 A Crystal Structure of Heat-Labile Shrimp Alkaline Phosphatase
pubmed doi rcsb
total genus 188
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2001-10-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1k7hA00
4UORA 3TWZA 5C66A 5L0BA 3UN3A 1ALHA 3TX0A 4GTZA 5LQQA 2RH6A 1ALKA 1ZEFA 3WAXA 4MIVA 3NKMA 3T01A 3UNYA 3IGZB 3BDHA 1EW9A 3NKNA 2W5SA 1E33P 3M8YA 2GLQA 2W8SA 1EJJA 1KH7A 3BDGB 1KHKA 4CYRA 2W5QA 3M8WA 4ZGAA 1P49A 5GRRA 5EGHA 4LRDA 2W5TA 3ED4A 2IFYA 4LRFA 4QAXA 5L0EA 1E3CP 4B56A 4CXUA 3TG0A 1HDHA 3WAWA 1KH9A 3DPCA 1KHJA 1ZEDA 4LRCA 1AJAA 5IJSA 2IUCA 2W5RA 2W8DA 1FSUA 1KHNA 1O98A 4NWJA 4UPIA 2QZUA 5LRMA 2D1GA 5EGEA 1AUKA 1ELZA 4LQYA 4CXSA 4N7TA 1ED8A 5INHA 3NKRA 3NKPA 4CYSA 3MK0A 3KD8A 3Q3QA 5LIAA 1SHQA 3SZYA 4KJDA 4LREA 5K4PA 3UN2A 4UPLA 4KM4A 4FDIA 3T00A 1ALJA 3OT9A 4MY4A 3SZZA 1URBA 1N2LA 1ED9A 3BDGA 4YR1A 4LR9A 3UO0A 1HQAA 2XR9A 4KAVA 4GTWA 1EI6A 1ELXA 4KJGA 5DLTA 5TJ3A 4CXKA 4TN0A 4UOOA 2GSUA 3WBHA 3BDFA 4LR7A 3UN5A 2GSNA 1KHLA 2GA3A 2ANHA 2W5XA 1EQJA 5LRNA 3NKOA 1AJDA 3MK1A 1URAA 2W5WA 3E2DA 3B5QA 1E1ZP 3LXQA 3NVLA 5AJ9A 1ANIA 5HRTA 4GTXA 3WAYA 1N2KA 4ZG6A 5GOVA 1Y7AA 2W5VA 1ALIA 2X98A 2VQRA 3NKQA 3M8ZA 2G9YA 1AJCA 5DLWA 1ANJA 1Y6VA 1EW8A 1EW2A 4UOPA 4FDJA 1O99A 2ZKTA 4ZG7A 3MK2A 2XRGA 4ZG9A 4LRAA 4UPHA 2GSOA 3T02A 4MHXA 3CMRA 3IGYB 1SHNA 3WAVA 1K7HA 4LR8A 5L0KA 5DLVA 4KAYA 1KH5A 3M7VA 1ELYA 3IDDA 4NWXA 1ZEBA 1B8JA 3DYCA 5KXAA 4UPKA 4LRBA 3A52A 1AJBA 1HJKA 1KH4A 2IUCB 4GTYA 4LR2A 1E2SP 5IJQA
chains in the Genus database with same CATH superfamily
4UORA 3TWZA 5C66A 5L0BA 3UN3A 1ALHA 3TX0A 4GTZA 5LQQA 2RH6A 1ALKA 1ZEFA 3WAXA 4MIVA 3NKMA 3T01A 3UNYA 3IGZB 3BDHA 1EW9A 3NKNA 2W5SA 1E33P 3M8YA 2GLQA 2W8SA 1EJJA 1KH7A 3BDGB 1KHKA 4CYRA 2W5QA 3M8WA 4ZGAA 1P49A 5GRRA 5EGHA 4LRDA 2W5TA 3ED4A 2IFYA 4LRFA 4QAXA 5L0EA 1E3CP 4B56A 4CXUA 3TG0A 1HDHA 3WAWA 1KH9A 3DPCA 1KHJA 1ZEDA 4LRCA 1AJAA 5IJSA 2IUCA 2W5RA 2W8DA 1FSUA 1KHNA 1O98A 4NWJA 4UPIA 2QZUA 5LRMA 2D1GA 5EGEA 1AUKA 1ELZA 4LQYA 4CXSA 4N7TA 1ED8A 5INHA 3NKRA 3NKPA 4CYSA 3MK0A 3KD8A 3Q3QA 5LIAA 1SHQA 3SZYA 4KJDA 4LREA 5K4PA 3UN2A 4UPLA 4KM4A 4FDIA 3T00A 1ALJA 3OT9A 4MY4A 3SZZA 1URBA 1N2LA 1ED9A 3BDGA 4YR1A 4LR9A 3UO0A 1HQAA 2XR9A 4KAVA 4GTWA 1EI6A 1ELXA 4KJGA 5DLTA 5TJ3A 4CXKA 4TN0A 4UOOA 2GSUA 3WBHA 3BDFA 4LR7A 3UN5A 2GSNA 1KHLA 2GA3A 2ANHA 2W5XA 1EQJA 5LRNA 3NKOA 1AJDA 3MK1A 1URAA 2W5WA 3E2DA 3B5QA 1E1ZP 3LXQA 3NVLA 5AJ9A 1ANIA 5HRTA 4GTXA 3WAYA 1N2KA 4ZG6A 5GOVA 1Y7AA 2W5VA 1ALIA 2X98A 2VQRA 3NKQA 3M8ZA 2G9YA 1AJCA 5DLWA 1ANJA 1Y6VA 1EW8A 1EW2A 4UOPA 4FDJA 1O99A 2ZKTA 4ZG7A 3MK2A 2XRGA 4ZG9A 4LRAA 4UPHA 2GSOA 3T02A 4MHXA 3CMRA 3IGYB 1SHNA 3WAVA 1K7HA 4LR8A 5L0KA 5DLVA 4KAYA 1KH5A 3M7VA 1ELYA 3IDDA 4NWXA 1ZEBA 1B8JA 3DYCA 5KXAA 4UPKA 4LRBA 3A52A 1AJBA 1HJKA 1KH4A 2IUCB 4GTYA 4LR2A 1E2SP 5IJQA
chains in the Genus database with same CATH topology
4UORA 3TWZA 5C66A 5L0BA 3UN3A 1ALHA 3TX0A 4GTZA 5LQQA 2RH6A 1ALKA 1ZEFA 3WAXA 4MIVA 3NKMA 3T01A 3UNYA 3IGZB 3BDHA 1EW9A 3NKNA 2W5SA 1E33P 3M8YA 2GLQA 2W8SA 1EJJA 1KH7A 3BDGB 1KHKA 4CYRA 2W5QA 3M8WA 4ZGAA 1P49A 5GRRA 5EGHA 4LRDA 2W5TA 3ED4A 2IFYA 4LRFA 4QAXA 5L0EA 1E3CP 4B56A 4CXUA 3TG0A 1HDHA 3WAWA 1KH9A 3DPCA 1KHJA 1ZEDA 4LRCA 1AJAA 5IJSA 2IUCA 2W5RA 2W8DA 1FSUA 1KHNA 1O98A 4NWJA 4UPIA 2QZUA 5LRMA 2D1GA 5EGEA 1AUKA 1ELZA 4LQYA 4CXSA 4N7TA 1ED8A 5INHA 3NKRA 3NKPA 4CYSA 3MK0A 3KD8A 3Q3QA 5LIAA 1SHQA 3SZYA 4KJDA 4LREA 5K4PA 3UN2A 4UPLA 4KM4A 4FDIA 3T00A 1ALJA 3OT9A 4MY4A 3SZZA 1URBA 1N2LA 1ED9A 3BDGA 4YR1A 4LR9A 3UO0A 1HQAA 2XR9A 4KAVA 4GTWA 1EI6A 1ELXA 4KJGA 5DLTA 5TJ3A 4CXKA 4TN0A 4UOOA 2GSUA 3WBHA 3BDFA 4LR7A 3UN5A 2GSNA 1KHLA 2GA3A 2ANHA 2W5XA 1EQJA 5LRNA 3NKOA 1AJDA 3MK1A 1URAA 2W5WA 3E2DA 3B5QA 1E1ZP 3LXQA 3NVLA 5AJ9A 1ANIA 5HRTA 4GTXA 3WAYA 1N2KA 4ZG6A 5GOVA 1Y7AA 2W5VA 1ALIA 2X98A 2VQRA 3NKQA 3M8ZA 2G9YA 1AJCA 5DLWA 1ANJA 1Y6VA 1EW8A 1EW2A 4UOPA 4FDJA 1O99A 2ZKTA 4ZG7A 3MK2A 2XRGA 4ZG9A 4LRAA 4UPHA 2GSOA 3T02A 4MHXA 3CMRA 3IGYB 1SHNA 3WAVA 1K7HA 4LR8A 5L0KA 5DLVA 4KAYA 1KH5A 3M7VA 1ELYA 3IDDA 4NWXA 1ZEBA 1B8JA 3DYCA 5KXAA 4UPKA 4LRBA 3A52A 1AJBA 1HJKA 1KH4A 2IUCB 4GTYA 4LR2A 1E2SP 5IJQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UOR A;  3TWZ A;  5C66 A;  5L0B A;  3UN3 A;  1ALH A;  3TX0 A;  4GTZ A;  5LQQ A;  2RH6 A;  1ALK A;  1ZEF A;  3WAX A;  4MIV A;  3NKM A;  3T01 A;  3UNY A;  3IGZ B;  3BDH A;  1EW9 A;  3NKN A;  2W5S A;  1E33 P;  3M8Y A;  2GLQ A;  2W8S A;  1EJJ A;  1KH7 A;  3BDG B;  1KHK A;  4CYR A;  2W5Q A;  3M8W A;  4ZGA A;  1P49 A;  5GRR A;  5EGH A;  4LRD A;  2W5T A;  3ED4 A;  2IFY A;  4LRF A;  4QAX A;  5L0E A;  1E3C P;  4B56 A;  4CXU A;  3TG0 A;  1HDH A;  3WAW A;  1KH9 A;  3DPC A;  1KHJ A;  1ZED A;  4LRC A;  1AJA A;  5IJS A;  2IUC A;  2W5R A;  2W8D A;  1FSU A;  1KHN A;  1O98 A;  4NWJ A;  4UPI A;  2QZU A;  5LRM A;  2D1G A;  5EGE A;  1AUK A;  1ELZ A;  4LQY A;  4CXS A;  4N7T A;  1ED8 A;  5INH A;  3NKR A;  3NKP A;  4CYS A;  3MK0 A;  3KD8 A;  3Q3Q A;  5LIA A;  1SHQ A;  3SZY A;  4KJD A;  4LRE A;  5K4P A;  3UN2 A;  4UPL A;  4KM4 A;  4FDI A;  3T00 A;  1ALJ A;  3OT9 A;  4MY4 A;  3SZZ A;  1URB A;  1N2L A;  1ED9 A;  3BDG A;  4YR1 A;  4LR9 A;  3UO0 A;  1HQA A;  2XR9 A;  4KAV A;  4GTW A;  1EI6 A;  1ELX A;  4KJG A;  5DLT A;  5TJ3 A;  4CXK A;  4TN0 A;  4UOO A;  2GSU A;  3WBH A;  3BDF A;  4LR7 A;  3UN5 A;  2GSN A;  1KHL A;  2GA3 A;  2ANH A;  2W5X A;  1EQJ A;  5LRN A;  3NKO A;  1AJD A;  3MK1 A;  1URA A;  2W5W A;  3E2D A;  3B5Q A;  1E1Z P;  3LXQ A;  3NVL A;  5AJ9 A;  1ANI A;  5HRT A;  4GTX A;  3WAY A;  1N2K A;  4ZG6 A;  5GOV A;  1Y7A A;  2W5V A;  1ALI A;  2X98 A;  2VQR A;  3NKQ A;  3M8Z A;  2G9Y A;  1AJC A;  5DLW A;  1ANJ A;  1Y6V A;  1EW8 A;  1EW2 A;  4UOP A;  4FDJ A;  1O99 A;  2ZKT A;  4ZG7 A;  3MK2 A;  2XRG A;  4ZG9 A;  4LRA A;  4UPH A;  2GSO A;  3T02 A;  4MHX A;  3CMR A;  3IGY B;  1SHN A;  3WAV A;  1K7H A;  4LR8 A;  5L0K A;  5DLV A;  4KAY A;  1KH5 A;  3M7V A;  1ELY A;  3IDD A;  4NWX A;  1ZEB A;  1B8J A;  3DYC A;  5KXA A;  4UPK A;  4LRB A;  3A52 A;  1AJB A;  1HJK A;  1KH4 A;  2IUC B;  4GTY A;  4LR2 A;  1E2S P;  5IJQ A; 
#chains in the Genus database with same CATH topology
 4UOR A;  3TWZ A;  5C66 A;  5L0B A;  3UN3 A;  1ALH A;  3TX0 A;  4GTZ A;  5LQQ A;  2RH6 A;  1ALK A;  1ZEF A;  3WAX A;  4MIV A;  3NKM A;  3T01 A;  3UNY A;  3IGZ B;  3BDH A;  1EW9 A;  3NKN A;  2W5S A;  1E33 P;  3M8Y A;  2GLQ A;  2W8S A;  1EJJ A;  1KH7 A;  3BDG B;  1KHK A;  4CYR A;  2W5Q A;  3M8W A;  4ZGA A;  1P49 A;  5GRR A;  5EGH A;  4LRD A;  2W5T A;  3ED4 A;  2IFY A;  4LRF A;  4QAX A;  5L0E A;  1E3C P;  4B56 A;  4CXU A;  3TG0 A;  1HDH A;  3WAW A;  1KH9 A;  3DPC A;  1KHJ A;  1ZED A;  4LRC A;  1AJA A;  5IJS A;  2IUC A;  2W5R A;  2W8D A;  1FSU A;  1KHN A;  1O98 A;  4NWJ A;  4UPI A;  2QZU A;  5LRM A;  2D1G A;  5EGE A;  1AUK A;  1ELZ A;  4LQY A;  4CXS A;  4N7T A;  1ED8 A;  5INH A;  3NKR A;  3NKP A;  4CYS A;  3MK0 A;  3KD8 A;  3Q3Q A;  5LIA A;  1SHQ A;  3SZY A;  4KJD A;  4LRE A;  5K4P A;  3UN2 A;  4UPL A;  4KM4 A;  4FDI A;  3T00 A;  1ALJ A;  3OT9 A;  4MY4 A;  3SZZ A;  1URB A;  1N2L A;  1ED9 A;  3BDG A;  4YR1 A;  4LR9 A;  3UO0 A;  1HQA A;  2XR9 A;  4KAV A;  4GTW A;  1EI6 A;  1ELX A;  4KJG A;  5DLT A;  5TJ3 A;  4CXK A;  4TN0 A;  4UOO A;  2GSU A;  3WBH A;  3BDF A;  4LR7 A;  3UN5 A;  2GSN A;  1KHL A;  2GA3 A;  2ANH A;  2W5X A;  1EQJ A;  5LRN A;  3NKO A;  1AJD A;  3MK1 A;  1URA A;  2W5W A;  3E2D A;  3B5Q A;  1E1Z P;  3LXQ A;  3NVL A;  5AJ9 A;  1ANI A;  5HRT A;  4GTX A;  3WAY A;  1N2K A;  4ZG6 A;  5GOV A;  1Y7A A;  2W5V A;  1ALI A;  2X98 A;  2VQR A;  3NKQ A;  3M8Z A;  2G9Y A;  1AJC A;  5DLW A;  1ANJ A;  1Y6V A;  1EW8 A;  1EW2 A;  4UOP A;  4FDJ A;  1O99 A;  2ZKT A;  4ZG7 A;  3MK2 A;  2XRG A;  4ZG9 A;  4LRA A;  4UPH A;  2GSO A;  3T02 A;  4MHX A;  3CMR A;  3IGY B;  1SHN A;  3WAV A;  1K7H A;  4LR8 A;  5L0K A;  5DLV A;  4KAY A;  1KH5 A;  3M7V A;  1ELY A;  3IDD A;  4NWX A;  1ZEB A;  1B8J A;  3DYC A;  5KXA A;  4UPK A;  4LRB A;  3A52 A;  1AJB A;  1HJK A;  1KH4 A;  2IUC B;  4GTY A;  4LR2 A;  1E2S P;  5IJQ A; 
#chains in the Genus database with same CATH homology
 4UOR A;  3TWZ A;  5C66 A;  5L0B A;  3UN3 A;  1ALH A;  3TX0 A;  4GTZ A;  5LQQ A;  2RH6 A;  1ALK A;  1ZEF A;  3WAX A;  4MIV A;  3NKM A;  3T01 A;  3UNY A;  3IGZ B;  3BDH A;  1EW9 A;  3NKN A;  2W5S A;  1E33 P;  3M8Y A;  2GLQ A;  2W8S A;  1EJJ A;  1KH7 A;  3BDG B;  1KHK A;  4CYR A;  2W5Q A;  3M8W A;  4ZGA A;  1P49 A;  5GRR A;  5EGH A;  4LRD A;  2W5T A;  3ED4 A;  2IFY A;  4LRF A;  4QAX A;  5L0E A;  1E3C P;  4B56 A;  4CXU A;  3TG0 A;  1HDH A;  3WAW A;  1KH9 A;  3DPC A;  1KHJ A;  1ZED A;  4LRC A;  1AJA A;  5IJS A;  2IUC A;  2W5R A;  2W8D A;  1FSU A;  1KHN A;  1O98 A;  4NWJ A;  4UPI A;  2QZU A;  5LRM A;  2D1G A;  5EGE A;  1AUK A;  1ELZ A;  4LQY A;  4CXS A;  4N7T A;  1ED8 A;  5INH A;  3NKR A;  3NKP A;  4CYS A;  3MK0 A;  3KD8 A;  3Q3Q A;  5LIA A;  1SHQ A;  3SZY A;  4KJD A;  4LRE A;  5K4P A;  3UN2 A;  4UPL A;  4KM4 A;  4FDI A;  3T00 A;  1ALJ A;  3OT9 A;  4MY4 A;  3SZZ A;  1URB A;  1N2L A;  1ED9 A;  3BDG A;  4YR1 A;  4LR9 A;  3UO0 A;  1HQA A;  2XR9 A;  4KAV A;  4GTW A;  1EI6 A;  1ELX A;  4KJG A;  5DLT A;  5TJ3 A;  4CXK A;  4TN0 A;  4UOO A;  2GSU A;  3WBH A;  3BDF A;  4LR7 A;  3UN5 A;  2GSN A;  1KHL A;  2GA3 A;  2ANH A;  2W5X A;  1EQJ A;  5LRN A;  3NKO A;  1AJD A;  3MK1 A;  1URA A;  2W5W A;  3E2D A;  3B5Q A;  1E1Z P;  3LXQ A;  3NVL A;  5AJ9 A;  1ANI A;  5HRT A;  4GTX A;  3WAY A;  1N2K A;  4ZG6 A;  5GOV A;  1Y7A A;  2W5V A;  1ALI A;  2X98 A;  2VQR A;  3NKQ A;  3M8Z A;  2G9Y A;  1AJC A;  5DLW A;  1ANJ A;  1Y6V A;  1EW8 A;  1EW2 A;  4UOP A;  4FDJ A;  1O99 A;  2ZKT A;  4ZG7 A;  3MK2 A;  2XRG A;  4ZG9 A;  4LRA A;  4UPH A;  2GSO A;  3T02 A;  4MHX A;  3CMR A;  3IGY B;  1SHN A;  3WAV A;  1K7H A;  4LR8 A;  5L0K A;  5DLV A;  4KAY A;  1KH5 A;  3M7V A;  1ELY A;  3IDD A;  4NWX A;  1ZEB A;  1B8J A;  3DYC A;  5KXA A;  4UPK A;  4LRB A;  3A52 A;  1AJB A;  1HJK A;  1KH4 A;  2IUC B;  4GTY A;  4LR2 A;  1E2S P;  5IJQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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