3TG0A

E. coli alkaline phosphatase with bound inorganic phosphate
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
Knots found
sequence length
440
structure length
440
Chain Sequence
NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 164
structure length 440
sequence length 440
chains with identical sequence B, C, D
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3tg0A00
4CYSA 3WAWA 2GLQA 1ANJA 3NKQA 5L0BA 4MHXA 2ANHA 1ALJA 1ED8A 1EW8A 4FDIA 1SHNA 2W5RA 2W5TA 1K7HA 1O99A 2W5WA 2IFYA 3A52A 2XR9A 3T02A 3IGYB 3TWZA 4KAYA 3UN3A 5LRNA 1E33P 4GTWA 5INHA 4KM4A 1URBA 1ALKA 2IUCB 4UORA 3DYCA 4MY4A 4LR7A 1N2LA 3IDDA 2VQRA 3KD8A 5C66A 2GSUA 3M8WA 3T01A 1EJJA 2D1GA 3LXQA 5DLTA 3WAVA 4B56A 2W8SA 4FDJA 3UN2A 3NKNA 2W5SA 3B5QA 5KXAA 4GTXA 1KHKA 5K4PA 4KJGA 4LRCA 1EQJA 1HDHA 4UOPA 3BDHA 5LIAA 4ZG7A 1KHJA 1ELXA 5IJSA 1ZEFA 4KJDA 5LQQA 1N2KA 1KH4A 1Y7AA 3OT9A 1E2SP 4LRBA 1ZEDA 2ZKTA 3NKPA 3BDGB 3NKRA 1AJDA 4GTZA 1HJKA 4LR2A 3UNYA 3E2DA 3UO0A 4QAXA 1HQAA 3NKOA 1P49A 1ELZA 1KHLA 5GRRA 1ZEBA 4ZG6A 4UOOA 3M8YA 4NWJA 3BDGA 3BDFA 2XRGA 3WAYA 1EW2A 1E1ZP 5TJ3A 4LQYA 3WBHA 1KHNA 2GA3A 1EW9A 4LRFA 1AJAA 2W8DA 3UN5A 4LRAA 1SHQA 3MK2A 2W5XA 5GOVA 4CXUA 1EI6A 1KH9A 3DPCA 4UPLA 2RH6A 3TG0A 4KAVA 3SZZA 2GSNA 2W5QA 4N7TA 4UPHA 4YR1A 1Y6VA 3MK1A 4CXSA 5DLVA 3Q3QA 3WAXA 1ED9A 3TX0A 2QZUA 1AJCA 4CXKA 4LR9A 3M7VA 3NKMA 4LR8A 3M8ZA 4CYRA 1O98A 3ED4A 1KH7A 1ALHA 1URAA 4UPKA 1KH5A 5L0EA 1ANIA 1AJBA 4UPIA 2W5VA 5EGHA 4ZG9A 2GSOA 3CMRA 5EGEA 5L0KA 5AJ9A 5HRTA 2G9YA 4TN0A 4ZGAA 1E3CP 4GTYA 1ELYA 1AUKA 5DLWA 1ALIA 5LRMA 3MK0A 4NWXA 4LREA 4MIVA 1FSUA 3IGZB 5IJQA 3NVLA 4LRDA 2IUCA 3SZYA 1B8JA 3T00A 2X98A
chains in the Genus database with same CATH superfamily
4CYSA 3WAWA 2GLQA 1ANJA 3NKQA 5L0BA 4MHXA 2ANHA 1ALJA 1ED8A 1EW8A 4FDIA 1SHNA 2W5RA 2W5TA 1K7HA 1O99A 2W5WA 2IFYA 3A52A 2XR9A 3T02A 3IGYB 3TWZA 4KAYA 3UN3A 5LRNA 1E33P 4GTWA 5INHA 4KM4A 1URBA 1ALKA 2IUCB 4UORA 3DYCA 4MY4A 4LR7A 1N2LA 3IDDA 2VQRA 3KD8A 5C66A 2GSUA 3M8WA 3T01A 1EJJA 2D1GA 3LXQA 5DLTA 3WAVA 4B56A 2W8SA 4FDJA 3UN2A 3NKNA 2W5SA 3B5QA 5KXAA 4GTXA 1KHKA 5K4PA 4KJGA 4LRCA 1EQJA 1HDHA 4UOPA 3BDHA 5LIAA 4ZG7A 1KHJA 1ELXA 5IJSA 1ZEFA 4KJDA 5LQQA 1N2KA 1KH4A 1Y7AA 3OT9A 1E2SP 4LRBA 1ZEDA 2ZKTA 3NKPA 3BDGB 3NKRA 1AJDA 4GTZA 1HJKA 4LR2A 3UNYA 3E2DA 3UO0A 4QAXA 1HQAA 3NKOA 1P49A 1ELZA 1KHLA 5GRRA 1ZEBA 4ZG6A 4UOOA 3M8YA 4NWJA 3BDGA 3BDFA 2XRGA 3WAYA 1EW2A 1E1ZP 5TJ3A 4LQYA 3WBHA 1KHNA 2GA3A 1EW9A 4LRFA 1AJAA 2W8DA 3UN5A 4LRAA 1SHQA 3MK2A 2W5XA 5GOVA 4CXUA 1EI6A 1KH9A 3DPCA 4UPLA 2RH6A 3TG0A 4KAVA 3SZZA 2GSNA 2W5QA 4N7TA 4UPHA 4YR1A 1Y6VA 3MK1A 4CXSA 5DLVA 3Q3QA 3WAXA 1ED9A 3TX0A 2QZUA 1AJCA 4CXKA 4LR9A 3M7VA 3NKMA 4LR8A 3M8ZA 4CYRA 1O98A 3ED4A 1KH7A 1ALHA 1URAA 4UPKA 1KH5A 5L0EA 1ANIA 1AJBA 4UPIA 2W5VA 5EGHA 4ZG9A 2GSOA 3CMRA 5EGEA 5L0KA 5AJ9A 5HRTA 2G9YA 4TN0A 4ZGAA 1E3CP 4GTYA 1ELYA 1AUKA 5DLWA 1ALIA 5LRMA 3MK0A 4NWXA 4LREA 4MIVA 1FSUA 3IGZB 5IJQA 3NVLA 4LRDA 2IUCA 3SZYA 1B8JA 3T00A 2X98A
chains in the Genus database with same CATH topology
4CYSA 3WAWA 2GLQA 1ANJA 3NKQA 5L0BA 4MHXA 2ANHA 1ALJA 1ED8A 1EW8A 4FDIA 1SHNA 2W5RA 2W5TA 1K7HA 1O99A 2W5WA 2IFYA 3A52A 2XR9A 3T02A 3IGYB 3TWZA 4KAYA 3UN3A 5LRNA 1E33P 4GTWA 5INHA 4KM4A 1URBA 1ALKA 2IUCB 4UORA 3DYCA 4MY4A 4LR7A 1N2LA 3IDDA 2VQRA 3KD8A 5C66A 2GSUA 3M8WA 3T01A 1EJJA 2D1GA 3LXQA 5DLTA 3WAVA 4B56A 2W8SA 4FDJA 3UN2A 3NKNA 2W5SA 3B5QA 5KXAA 4GTXA 1KHKA 5K4PA 4KJGA 4LRCA 1EQJA 1HDHA 4UOPA 3BDHA 5LIAA 4ZG7A 1KHJA 1ELXA 5IJSA 1ZEFA 4KJDA 5LQQA 1N2KA 1KH4A 1Y7AA 3OT9A 1E2SP 4LRBA 1ZEDA 2ZKTA 3NKPA 3BDGB 3NKRA 1AJDA 4GTZA 1HJKA 4LR2A 3UNYA 3E2DA 3UO0A 4QAXA 1HQAA 3NKOA 1P49A 1ELZA 1KHLA 5GRRA 1ZEBA 4ZG6A 4UOOA 3M8YA 4NWJA 3BDGA 3BDFA 2XRGA 3WAYA 1EW2A 1E1ZP 5TJ3A 4LQYA 3WBHA 1KHNA 2GA3A 1EW9A 4LRFA 1AJAA 2W8DA 3UN5A 4LRAA 1SHQA 3MK2A 2W5XA 5GOVA 4CXUA 1EI6A 1KH9A 3DPCA 4UPLA 2RH6A 3TG0A 4KAVA 3SZZA 2GSNA 2W5QA 4N7TA 4UPHA 4YR1A 1Y6VA 3MK1A 4CXSA 5DLVA 3Q3QA 3WAXA 1ED9A 3TX0A 2QZUA 1AJCA 4CXKA 4LR9A 3M7VA 3NKMA 4LR8A 3M8ZA 4CYRA 1O98A 3ED4A 1KH7A 1ALHA 1URAA 4UPKA 1KH5A 5L0EA 1ANIA 1AJBA 4UPIA 2W5VA 5EGHA 4ZG9A 2GSOA 3CMRA 5EGEA 5L0KA 5AJ9A 5HRTA 2G9YA 4TN0A 4ZGAA 1E3CP 4GTYA 1ELYA 1AUKA 5DLWA 1ALIA 5LRMA 3MK0A 4NWXA 4LREA 4MIVA 1FSUA 3IGZB 5IJQA 3NVLA 4LRDA 2IUCA 3SZYA 1B8JA 3T00A 2X98A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CYS A;  3WAW A;  2GLQ A;  1ANJ A;  3NKQ A;  5L0B A;  4MHX A;  2ANH A;  1ALJ A;  1ED8 A;  1EW8 A;  4FDI A;  1SHN A;  2W5R A;  2W5T A;  1K7H A;  1O99 A;  2W5W A;  2IFY A;  3A52 A;  2XR9 A;  3T02 A;  3IGY B;  3TWZ A;  4KAY A;  3UN3 A;  5LRN A;  1E33 P;  4GTW A;  5INH A;  4KM4 A;  1URB A;  1ALK A;  2IUC B;  4UOR A;  3DYC A;  4MY4 A;  4LR7 A;  1N2L A;  3IDD A;  2VQR A;  3KD8 A;  5C66 A;  2GSU A;  3M8W A;  3T01 A;  1EJJ A;  2D1G A;  3LXQ A;  5DLT A;  3WAV A;  4B56 A;  2W8S A;  4FDJ A;  3UN2 A;  3NKN A;  2W5S A;  3B5Q A;  5KXA A;  4GTX A;  1KHK A;  5K4P A;  4KJG A;  4LRC A;  1EQJ A;  1HDH A;  4UOP A;  3BDH A;  5LIA A;  4ZG7 A;  1KHJ A;  1ELX A;  5IJS A;  1ZEF A;  4KJD A;  5LQQ A;  1N2K A;  1KH4 A;  1Y7A A;  3OT9 A;  1E2S P;  4LRB A;  1ZED A;  2ZKT A;  3NKP A;  3BDG B;  3NKR A;  1AJD A;  4GTZ A;  1HJK A;  4LR2 A;  3UNY A;  3E2D A;  3UO0 A;  4QAX A;  1HQA A;  3NKO A;  1P49 A;  1ELZ A;  1KHL A;  5GRR A;  1ZEB A;  4ZG6 A;  4UOO A;  3M8Y A;  4NWJ A;  3BDG A;  3BDF A;  2XRG A;  3WAY A;  1EW2 A;  1E1Z P;  5TJ3 A;  4LQY A;  3WBH A;  1KHN A;  2GA3 A;  1EW9 A;  4LRF A;  1AJA A;  2W8D A;  3UN5 A;  4LRA A;  1SHQ A;  3MK2 A;  2W5X A;  5GOV A;  4CXU A;  1EI6 A;  1KH9 A;  3DPC A;  4UPL A;  2RH6 A;  3TG0 A;  4KAV A;  3SZZ A;  2GSN A;  2W5Q A;  4N7T A;  4UPH A;  4YR1 A;  1Y6V A;  3MK1 A;  4CXS A;  5DLV A;  3Q3Q A;  3WAX A;  1ED9 A;  3TX0 A;  2QZU A;  1AJC A;  4CXK A;  4LR9 A;  3M7V A;  3NKM A;  4LR8 A;  3M8Z A;  4CYR A;  1O98 A;  3ED4 A;  1KH7 A;  1ALH A;  1URA A;  4UPK A;  1KH5 A;  5L0E A;  1ANI A;  1AJB A;  4UPI A;  2W5V A;  5EGH A;  4ZG9 A;  2GSO A;  3CMR A;  5EGE A;  5L0K A;  5AJ9 A;  5HRT A;  2G9Y A;  4TN0 A;  4ZGA A;  1E3C P;  4GTY A;  1ELY A;  1AUK A;  5DLW A;  1ALI A;  5LRM A;  3MK0 A;  4NWX A;  4LRE A;  4MIV A;  1FSU A;  3IGZ B;  5IJQ A;  3NVL A;  4LRD A;  2IUC A;  3SZY A;  1B8J A;  3T00 A;  2X98 A; 
#chains in the Genus database with same CATH topology
 4CYS A;  3WAW A;  2GLQ A;  1ANJ A;  3NKQ A;  5L0B A;  4MHX A;  2ANH A;  1ALJ A;  1ED8 A;  1EW8 A;  4FDI A;  1SHN A;  2W5R A;  2W5T A;  1K7H A;  1O99 A;  2W5W A;  2IFY A;  3A52 A;  2XR9 A;  3T02 A;  3IGY B;  3TWZ A;  4KAY A;  3UN3 A;  5LRN A;  1E33 P;  4GTW A;  5INH A;  4KM4 A;  1URB A;  1ALK A;  2IUC B;  4UOR A;  3DYC A;  4MY4 A;  4LR7 A;  1N2L A;  3IDD A;  2VQR A;  3KD8 A;  5C66 A;  2GSU A;  3M8W A;  3T01 A;  1EJJ A;  2D1G A;  3LXQ A;  5DLT A;  3WAV A;  4B56 A;  2W8S A;  4FDJ A;  3UN2 A;  3NKN A;  2W5S A;  3B5Q A;  5KXA A;  4GTX A;  1KHK A;  5K4P A;  4KJG A;  4LRC A;  1EQJ A;  1HDH A;  4UOP A;  3BDH A;  5LIA A;  4ZG7 A;  1KHJ A;  1ELX A;  5IJS A;  1ZEF A;  4KJD A;  5LQQ A;  1N2K A;  1KH4 A;  1Y7A A;  3OT9 A;  1E2S P;  4LRB A;  1ZED A;  2ZKT A;  3NKP A;  3BDG B;  3NKR A;  1AJD A;  4GTZ A;  1HJK A;  4LR2 A;  3UNY A;  3E2D A;  3UO0 A;  4QAX A;  1HQA A;  3NKO A;  1P49 A;  1ELZ A;  1KHL A;  5GRR A;  1ZEB A;  4ZG6 A;  4UOO A;  3M8Y A;  4NWJ A;  3BDG A;  3BDF A;  2XRG A;  3WAY A;  1EW2 A;  1E1Z P;  5TJ3 A;  4LQY A;  3WBH A;  1KHN A;  2GA3 A;  1EW9 A;  4LRF A;  1AJA A;  2W8D A;  3UN5 A;  4LRA A;  1SHQ A;  3MK2 A;  2W5X A;  5GOV A;  4CXU A;  1EI6 A;  1KH9 A;  3DPC A;  4UPL A;  2RH6 A;  3TG0 A;  4KAV A;  3SZZ A;  2GSN A;  2W5Q A;  4N7T A;  4UPH A;  4YR1 A;  1Y6V A;  3MK1 A;  4CXS A;  5DLV A;  3Q3Q A;  3WAX A;  1ED9 A;  3TX0 A;  2QZU A;  1AJC A;  4CXK A;  4LR9 A;  3M7V A;  3NKM A;  4LR8 A;  3M8Z A;  4CYR A;  1O98 A;  3ED4 A;  1KH7 A;  1ALH A;  1URA A;  4UPK A;  1KH5 A;  5L0E A;  1ANI A;  1AJB A;  4UPI A;  2W5V A;  5EGH A;  4ZG9 A;  2GSO A;  3CMR A;  5EGE A;  5L0K A;  5AJ9 A;  5HRT A;  2G9Y A;  4TN0 A;  4ZGA A;  1E3C P;  4GTY A;  1ELY A;  1AUK A;  5DLW A;  1ALI A;  5LRM A;  3MK0 A;  4NWX A;  4LRE A;  4MIV A;  1FSU A;  3IGZ B;  5IJQ A;  3NVL A;  4LRD A;  2IUC A;  3SZY A;  1B8J A;  3T00 A;  2X98 A; 
#chains in the Genus database with same CATH homology
 4CYS A;  3WAW A;  2GLQ A;  1ANJ A;  3NKQ A;  5L0B A;  4MHX A;  2ANH A;  1ALJ A;  1ED8 A;  1EW8 A;  4FDI A;  1SHN A;  2W5R A;  2W5T A;  1K7H A;  1O99 A;  2W5W A;  2IFY A;  3A52 A;  2XR9 A;  3T02 A;  3IGY B;  3TWZ A;  4KAY A;  3UN3 A;  5LRN A;  1E33 P;  4GTW A;  5INH A;  4KM4 A;  1URB A;  1ALK A;  2IUC B;  4UOR A;  3DYC A;  4MY4 A;  4LR7 A;  1N2L A;  3IDD A;  2VQR A;  3KD8 A;  5C66 A;  2GSU A;  3M8W A;  3T01 A;  1EJJ A;  2D1G A;  3LXQ A;  5DLT A;  3WAV A;  4B56 A;  2W8S A;  4FDJ A;  3UN2 A;  3NKN A;  2W5S A;  3B5Q A;  5KXA A;  4GTX A;  1KHK A;  5K4P A;  4KJG A;  4LRC A;  1EQJ A;  1HDH A;  4UOP A;  3BDH A;  5LIA A;  4ZG7 A;  1KHJ A;  1ELX A;  5IJS A;  1ZEF A;  4KJD A;  5LQQ A;  1N2K A;  1KH4 A;  1Y7A A;  3OT9 A;  1E2S P;  4LRB A;  1ZED A;  2ZKT A;  3NKP A;  3BDG B;  3NKR A;  1AJD A;  4GTZ A;  1HJK A;  4LR2 A;  3UNY A;  3E2D A;  3UO0 A;  4QAX A;  1HQA A;  3NKO A;  1P49 A;  1ELZ A;  1KHL A;  5GRR A;  1ZEB A;  4ZG6 A;  4UOO A;  3M8Y A;  4NWJ A;  3BDG A;  3BDF A;  2XRG A;  3WAY A;  1EW2 A;  1E1Z P;  5TJ3 A;  4LQY A;  3WBH A;  1KHN A;  2GA3 A;  1EW9 A;  4LRF A;  1AJA A;  2W8D A;  3UN5 A;  4LRA A;  1SHQ A;  3MK2 A;  2W5X A;  5GOV A;  4CXU A;  1EI6 A;  1KH9 A;  3DPC A;  4UPL A;  2RH6 A;  3TG0 A;  4KAV A;  3SZZ A;  2GSN A;  2W5Q A;  4N7T A;  4UPH A;  4YR1 A;  1Y6V A;  3MK1 A;  4CXS A;  5DLV A;  3Q3Q A;  3WAX A;  1ED9 A;  3TX0 A;  2QZU A;  1AJC A;  4CXK A;  4LR9 A;  3M7V A;  3NKM A;  4LR8 A;  3M8Z A;  4CYR A;  1O98 A;  3ED4 A;  1KH7 A;  1ALH A;  1URA A;  4UPK A;  1KH5 A;  5L0E A;  1ANI A;  1AJB A;  4UPI A;  2W5V A;  5EGH A;  4ZG9 A;  2GSO A;  3CMR A;  5EGE A;  5L0K A;  5AJ9 A;  5HRT A;  2G9Y A;  4TN0 A;  4ZGA A;  1E3C P;  4GTY A;  1ELY A;  1AUK A;  5DLW A;  1ALI A;  5LRM A;  3MK0 A;  4NWX A;  4LRE A;  4MIV A;  1FSU A;  3IGZ B;  5IJQ A;  3NVL A;  4LRD A;  2IUC A;  3SZY A;  1B8J A;  3T00 A;  2X98 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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