3TG0A

E. coli alkaline phosphatase with bound inorganic phosphate
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
Knots found
sequence length
440
structure length
440
Chain Sequence
NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Alkaline phosphatase
publication title High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
pubmed doi rcsb
source organism Escherichia coli
total genus 164
structure length 440
sequence length 440
chains with identical sequence B, C, D
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3tg0A00
3UNYA 3SZZA 1EW8A 3NKNA 4KAVA 5EGEA 1EW9A 1KHNA 3KD8A 4LRCA 3SZYA 1AJCA 3NKOA 1E33P 4MY4A 4UPKA 4UPHA 3UO0A 3M8WA 4LRAA 4GTZA 4FDJA 3M8YA 1N2KA 4KJDA 4LRBA 1AJDA 3M7VA 4LRDA 2XR9A 3T01A 4GTYA 3B5QA 4MIVA 1E2SP 1ELXA 3WAXA 2GA3A 3BDHA 1E3CP 3DPCA 3TX0A 4CYRA 1ZEFA 4KAYA 1P49A 2W8DA 2W5XA 5L0KA 2VQRA 5GRRA 1KH5A 1HDHA 1AJAA 4CXUA 1KHJA 3LXQA 4LR8A 4UOOA 1O98A 3WAVA 4ZGAA 4CXKA 1EW2A 4LR9A 4LQYA 4UPLA 2GSOA 3A52A 5AJ9A 1ANIA 5DLTA 4NWXA 2GLQA 1E1ZP 3NKPA 2GSUA 4N7TA 1URAA 2W5WA 5L0BA 3T00A 4GTXA 4MHXA 2QZUA 2IFYA 4ZG7A 2IUCA 3IGYB 2W5SA 5DLVA 3NVLA 3CMRA 1KH7A 4ZG9A 5L0EA 2ZKTA 1KH9A 3MK2A 5LRMA 1KHKA 1Y6VA 1HJKA 4FDIA 5KXAA 2G9YA 1EQJA 4UPIA 4LRFA 3UN3A 3E2DA 2W5VA 5TJ3A 4LR2A 3TWZA 5C66A 2GSNA 1ED9A 4CXSA 5LQQA 1URBA 3BDFA 1SHNA 3WAWA 2RH6A 3M8ZA 3MK0A 3IDDA 4GTWA 3Q3QA 2X98A 5HRTA 1KHLA 1ZEDA 3NKQA 2W5RA 2W5QA 1ED8A 4CYSA 1Y7AA 3DYCA 3NKRA 2XRGA 5K4PA 4KJGA 1AJBA 1SHQA 3TG0A 1ALJA 3T02A 3UN2A 1ALHA 1HQAA 4YR1A 1ANJA 4B56A 1ELZA 5EGHA 1K7HA 5IJSA 1AUKA 5IJQA 1ALIA 5LRNA 4UOPA 4ZG6A 3IGZB 3WAYA 3NKMA 1B8JA 2IUCB 1FSUA 1ALKA 5DLWA 3BDGA 5INHA 2D1GA 1N2LA 1EI6A 4UORA 5GOVA 1O99A 4KM4A 4LREA 2W8SA 1ZEBA 4NWJA 4TN0A 3UN5A 3BDGB 2ANHA 1EJJA 3OT9A 1ELYA 1KH4A 3MK1A 3WBHA 4QAXA 2W5TA 4LR7A 3ED4A 5LIAA
chains in the Genus database with same CATH superfamily
3UNYA 3SZZA 1EW8A 3NKNA 4KAVA 5EGEA 1EW9A 1KHNA 3KD8A 4LRCA 3SZYA 1AJCA 3NKOA 1E33P 4MY4A 4UPKA 4UPHA 3UO0A 3M8WA 4LRAA 4GTZA 4FDJA 3M8YA 1N2KA 4KJDA 4LRBA 1AJDA 3M7VA 4LRDA 2XR9A 3T01A 4GTYA 3B5QA 4MIVA 1E2SP 1ELXA 3WAXA 2GA3A 3BDHA 1E3CP 3DPCA 3TX0A 4CYRA 1ZEFA 4KAYA 1P49A 2W8DA 2W5XA 5L0KA 2VQRA 5GRRA 1KH5A 1HDHA 1AJAA 4CXUA 1KHJA 3LXQA 4LR8A 4UOOA 1O98A 3WAVA 4ZGAA 4CXKA 1EW2A 4LR9A 4LQYA 4UPLA 2GSOA 3A52A 5AJ9A 1ANIA 5DLTA 4NWXA 2GLQA 1E1ZP 3NKPA 2GSUA 4N7TA 1URAA 2W5WA 5L0BA 3T00A 4GTXA 4MHXA 2QZUA 2IFYA 4ZG7A 2IUCA 3IGYB 2W5SA 5DLVA 3NVLA 3CMRA 1KH7A 4ZG9A 5L0EA 2ZKTA 1KH9A 3MK2A 5LRMA 1KHKA 1Y6VA 1HJKA 4FDIA 5KXAA 2G9YA 1EQJA 4UPIA 4LRFA 3UN3A 3E2DA 2W5VA 5TJ3A 4LR2A 3TWZA 5C66A 2GSNA 1ED9A 4CXSA 5LQQA 1URBA 3BDFA 1SHNA 3WAWA 2RH6A 3M8ZA 3MK0A 3IDDA 4GTWA 3Q3QA 2X98A 5HRTA 1KHLA 1ZEDA 3NKQA 2W5RA 2W5QA 1ED8A 4CYSA 1Y7AA 3DYCA 3NKRA 2XRGA 5K4PA 4KJGA 1AJBA 1SHQA 3TG0A 1ALJA 3T02A 3UN2A 1ALHA 1HQAA 4YR1A 1ANJA 4B56A 1ELZA 5EGHA 1K7HA 5IJSA 1AUKA 5IJQA 1ALIA 5LRNA 4UOPA 4ZG6A 3IGZB 3WAYA 3NKMA 1B8JA 2IUCB 1FSUA 1ALKA 5DLWA 3BDGA 5INHA 2D1GA 1N2LA 1EI6A 4UORA 5GOVA 1O99A 4KM4A 4LREA 2W8SA 1ZEBA 4NWJA 4TN0A 3UN5A 3BDGB 2ANHA 1EJJA 3OT9A 1ELYA 1KH4A 3MK1A 3WBHA 4QAXA 2W5TA 4LR7A 3ED4A 5LIAA
chains in the Genus database with same CATH topology
3UNYA 3SZZA 1EW8A 3NKNA 4KAVA 5EGEA 1EW9A 1KHNA 3KD8A 4LRCA 3SZYA 1AJCA 3NKOA 1E33P 4MY4A 4UPKA 4UPHA 3UO0A 3M8WA 4LRAA 4GTZA 4FDJA 3M8YA 1N2KA 4KJDA 4LRBA 1AJDA 3M7VA 4LRDA 2XR9A 3T01A 4GTYA 3B5QA 4MIVA 1E2SP 1ELXA 3WAXA 2GA3A 3BDHA 1E3CP 3DPCA 3TX0A 4CYRA 1ZEFA 4KAYA 1P49A 2W8DA 2W5XA 5L0KA 2VQRA 5GRRA 1KH5A 1HDHA 1AJAA 4CXUA 1KHJA 3LXQA 4LR8A 4UOOA 1O98A 3WAVA 4ZGAA 4CXKA 1EW2A 4LR9A 4LQYA 4UPLA 2GSOA 3A52A 5AJ9A 1ANIA 5DLTA 4NWXA 2GLQA 1E1ZP 3NKPA 2GSUA 4N7TA 1URAA 2W5WA 5L0BA 3T00A 4GTXA 4MHXA 2QZUA 2IFYA 4ZG7A 2IUCA 3IGYB 2W5SA 5DLVA 3NVLA 3CMRA 1KH7A 4ZG9A 5L0EA 2ZKTA 1KH9A 3MK2A 5LRMA 1KHKA 1Y6VA 1HJKA 4FDIA 5KXAA 2G9YA 1EQJA 4UPIA 4LRFA 3UN3A 3E2DA 2W5VA 5TJ3A 4LR2A 3TWZA 5C66A 2GSNA 1ED9A 4CXSA 5LQQA 1URBA 3BDFA 1SHNA 3WAWA 2RH6A 3M8ZA 3MK0A 3IDDA 4GTWA 3Q3QA 2X98A 5HRTA 1KHLA 1ZEDA 3NKQA 2W5RA 2W5QA 1ED8A 4CYSA 1Y7AA 3DYCA 3NKRA 2XRGA 5K4PA 4KJGA 1AJBA 1SHQA 3TG0A 1ALJA 3T02A 3UN2A 1ALHA 1HQAA 4YR1A 1ANJA 4B56A 1ELZA 5EGHA 1K7HA 5IJSA 1AUKA 5IJQA 1ALIA 5LRNA 4UOPA 4ZG6A 3IGZB 3WAYA 3NKMA 1B8JA 2IUCB 1FSUA 1ALKA 5DLWA 3BDGA 5INHA 2D1GA 1N2LA 1EI6A 4UORA 5GOVA 1O99A 4KM4A 4LREA 2W8SA 1ZEBA 4NWJA 4TN0A 3UN5A 3BDGB 2ANHA 1EJJA 3OT9A 1ELYA 1KH4A 3MK1A 3WBHA 4QAXA 2W5TA 4LR7A 3ED4A 5LIAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UNY A;  3SZZ A;  1EW8 A;  3NKN A;  4KAV A;  5EGE A;  1EW9 A;  1KHN A;  3KD8 A;  4LRC A;  3SZY A;  1AJC A;  3NKO A;  1E33 P;  4MY4 A;  4UPK A;  4UPH A;  3UO0 A;  3M8W A;  4LRA A;  4GTZ A;  4FDJ A;  3M8Y A;  1N2K A;  4KJD A;  4LRB A;  1AJD A;  3M7V A;  4LRD A;  2XR9 A;  3T01 A;  4GTY A;  3B5Q A;  4MIV A;  1E2S P;  1ELX A;  3WAX A;  2GA3 A;  3BDH A;  1E3C P;  3DPC A;  3TX0 A;  4CYR A;  1ZEF A;  4KAY A;  1P49 A;  2W8D A;  2W5X A;  5L0K A;  2VQR A;  5GRR A;  1KH5 A;  1HDH A;  1AJA A;  4CXU A;  1KHJ A;  3LXQ A;  4LR8 A;  4UOO A;  1O98 A;  3WAV A;  4ZGA A;  4CXK A;  1EW2 A;  4LR9 A;  4LQY A;  4UPL A;  2GSO A;  3A52 A;  5AJ9 A;  1ANI A;  5DLT A;  4NWX A;  2GLQ A;  1E1Z P;  3NKP A;  2GSU A;  4N7T A;  1URA A;  2W5W A;  5L0B A;  3T00 A;  4GTX A;  4MHX A;  2QZU A;  2IFY A;  4ZG7 A;  2IUC A;  3IGY B;  2W5S A;  5DLV A;  3NVL A;  3CMR A;  1KH7 A;  4ZG9 A;  5L0E A;  2ZKT A;  1KH9 A;  3MK2 A;  5LRM A;  1KHK A;  1Y6V A;  1HJK A;  4FDI A;  5KXA A;  2G9Y A;  1EQJ A;  4UPI A;  4LRF A;  3UN3 A;  3E2D A;  2W5V A;  5TJ3 A;  4LR2 A;  3TWZ A;  5C66 A;  2GSN A;  1ED9 A;  4CXS A;  5LQQ A;  1URB A;  3BDF A;  1SHN A;  3WAW A;  2RH6 A;  3M8Z A;  3MK0 A;  3IDD A;  4GTW A;  3Q3Q A;  2X98 A;  5HRT A;  1KHL A;  1ZED A;  3NKQ A;  2W5R A;  2W5Q A;  1ED8 A;  4CYS A;  1Y7A A;  3DYC A;  3NKR A;  2XRG A;  5K4P A;  4KJG A;  1AJB A;  1SHQ A;  3TG0 A;  1ALJ A;  3T02 A;  3UN2 A;  1ALH A;  1HQA A;  4YR1 A;  1ANJ A;  4B56 A;  1ELZ A;  5EGH A;  1K7H A;  5IJS A;  1AUK A;  5IJQ A;  1ALI A;  5LRN A;  4UOP A;  4ZG6 A;  3IGZ B;  3WAY A;  3NKM A;  1B8J A;  2IUC B;  1FSU A;  1ALK A;  5DLW A;  3BDG A;  5INH A;  2D1G A;  1N2L A;  1EI6 A;  4UOR A;  5GOV A;  1O99 A;  4KM4 A;  4LRE A;  2W8S A;  1ZEB A;  4NWJ A;  4TN0 A;  3UN5 A;  3BDG B;  2ANH A;  1EJJ A;  3OT9 A;  1ELY A;  1KH4 A;  3MK1 A;  3WBH A;  4QAX A;  2W5T A;  4LR7 A;  3ED4 A;  5LIA A; 
#chains in the Genus database with same CATH topology
 3UNY A;  3SZZ A;  1EW8 A;  3NKN A;  4KAV A;  5EGE A;  1EW9 A;  1KHN A;  3KD8 A;  4LRC A;  3SZY A;  1AJC A;  3NKO A;  1E33 P;  4MY4 A;  4UPK A;  4UPH A;  3UO0 A;  3M8W A;  4LRA A;  4GTZ A;  4FDJ A;  3M8Y A;  1N2K A;  4KJD A;  4LRB A;  1AJD A;  3M7V A;  4LRD A;  2XR9 A;  3T01 A;  4GTY A;  3B5Q A;  4MIV A;  1E2S P;  1ELX A;  3WAX A;  2GA3 A;  3BDH A;  1E3C P;  3DPC A;  3TX0 A;  4CYR A;  1ZEF A;  4KAY A;  1P49 A;  2W8D A;  2W5X A;  5L0K A;  2VQR A;  5GRR A;  1KH5 A;  1HDH A;  1AJA A;  4CXU A;  1KHJ A;  3LXQ A;  4LR8 A;  4UOO A;  1O98 A;  3WAV A;  4ZGA A;  4CXK A;  1EW2 A;  4LR9 A;  4LQY A;  4UPL A;  2GSO A;  3A52 A;  5AJ9 A;  1ANI A;  5DLT A;  4NWX A;  2GLQ A;  1E1Z P;  3NKP A;  2GSU A;  4N7T A;  1URA A;  2W5W A;  5L0B A;  3T00 A;  4GTX A;  4MHX A;  2QZU A;  2IFY A;  4ZG7 A;  2IUC A;  3IGY B;  2W5S A;  5DLV A;  3NVL A;  3CMR A;  1KH7 A;  4ZG9 A;  5L0E A;  2ZKT A;  1KH9 A;  3MK2 A;  5LRM A;  1KHK A;  1Y6V A;  1HJK A;  4FDI A;  5KXA A;  2G9Y A;  1EQJ A;  4UPI A;  4LRF A;  3UN3 A;  3E2D A;  2W5V A;  5TJ3 A;  4LR2 A;  3TWZ A;  5C66 A;  2GSN A;  1ED9 A;  4CXS A;  5LQQ A;  1URB A;  3BDF A;  1SHN A;  3WAW A;  2RH6 A;  3M8Z A;  3MK0 A;  3IDD A;  4GTW A;  3Q3Q A;  2X98 A;  5HRT A;  1KHL A;  1ZED A;  3NKQ A;  2W5R A;  2W5Q A;  1ED8 A;  4CYS A;  1Y7A A;  3DYC A;  3NKR A;  2XRG A;  5K4P A;  4KJG A;  1AJB A;  1SHQ A;  3TG0 A;  1ALJ A;  3T02 A;  3UN2 A;  1ALH A;  1HQA A;  4YR1 A;  1ANJ A;  4B56 A;  1ELZ A;  5EGH A;  1K7H A;  5IJS A;  1AUK A;  5IJQ A;  1ALI A;  5LRN A;  4UOP A;  4ZG6 A;  3IGZ B;  3WAY A;  3NKM A;  1B8J A;  2IUC B;  1FSU A;  1ALK A;  5DLW A;  3BDG A;  5INH A;  2D1G A;  1N2L A;  1EI6 A;  4UOR A;  5GOV A;  1O99 A;  4KM4 A;  4LRE A;  2W8S A;  1ZEB A;  4NWJ A;  4TN0 A;  3UN5 A;  3BDG B;  2ANH A;  1EJJ A;  3OT9 A;  1ELY A;  1KH4 A;  3MK1 A;  3WBH A;  4QAX A;  2W5T A;  4LR7 A;  3ED4 A;  5LIA A; 
#chains in the Genus database with same CATH homology
 3UNY A;  3SZZ A;  1EW8 A;  3NKN A;  4KAV A;  5EGE A;  1EW9 A;  1KHN A;  3KD8 A;  4LRC A;  3SZY A;  1AJC A;  3NKO A;  1E33 P;  4MY4 A;  4UPK A;  4UPH A;  3UO0 A;  3M8W A;  4LRA A;  4GTZ A;  4FDJ A;  3M8Y A;  1N2K A;  4KJD A;  4LRB A;  1AJD A;  3M7V A;  4LRD A;  2XR9 A;  3T01 A;  4GTY A;  3B5Q A;  4MIV A;  1E2S P;  1ELX A;  3WAX A;  2GA3 A;  3BDH A;  1E3C P;  3DPC A;  3TX0 A;  4CYR A;  1ZEF A;  4KAY A;  1P49 A;  2W8D A;  2W5X A;  5L0K A;  2VQR A;  5GRR A;  1KH5 A;  1HDH A;  1AJA A;  4CXU A;  1KHJ A;  3LXQ A;  4LR8 A;  4UOO A;  1O98 A;  3WAV A;  4ZGA A;  4CXK A;  1EW2 A;  4LR9 A;  4LQY A;  4UPL A;  2GSO A;  3A52 A;  5AJ9 A;  1ANI A;  5DLT A;  4NWX A;  2GLQ A;  1E1Z P;  3NKP A;  2GSU A;  4N7T A;  1URA A;  2W5W A;  5L0B A;  3T00 A;  4GTX A;  4MHX A;  2QZU A;  2IFY A;  4ZG7 A;  2IUC A;  3IGY B;  2W5S A;  5DLV A;  3NVL A;  3CMR A;  1KH7 A;  4ZG9 A;  5L0E A;  2ZKT A;  1KH9 A;  3MK2 A;  5LRM A;  1KHK A;  1Y6V A;  1HJK A;  4FDI A;  5KXA A;  2G9Y A;  1EQJ A;  4UPI A;  4LRF A;  3UN3 A;  3E2D A;  2W5V A;  5TJ3 A;  4LR2 A;  3TWZ A;  5C66 A;  2GSN A;  1ED9 A;  4CXS A;  5LQQ A;  1URB A;  3BDF A;  1SHN A;  3WAW A;  2RH6 A;  3M8Z A;  3MK0 A;  3IDD A;  4GTW A;  3Q3Q A;  2X98 A;  5HRT A;  1KHL A;  1ZED A;  3NKQ A;  2W5R A;  2W5Q A;  1ED8 A;  4CYS A;  1Y7A A;  3DYC A;  3NKR A;  2XRG A;  5K4P A;  4KJG A;  1AJB A;  1SHQ A;  3TG0 A;  1ALJ A;  3T02 A;  3UN2 A;  1ALH A;  1HQA A;  4YR1 A;  1ANJ A;  4B56 A;  1ELZ A;  5EGH A;  1K7H A;  5IJS A;  1AUK A;  5IJQ A;  1ALI A;  5LRN A;  4UOP A;  4ZG6 A;  3IGZ B;  3WAY A;  3NKM A;  1B8J A;  2IUC B;  1FSU A;  1ALK A;  5DLW A;  3BDG A;  5INH A;  2D1G A;  1N2L A;  1EI6 A;  4UOR A;  5GOV A;  1O99 A;  4KM4 A;  4LRE A;  2W8S A;  1ZEB A;  4NWJ A;  4TN0 A;  3UN5 A;  3BDG B;  2ANH A;  1EJJ A;  3OT9 A;  1ELY A;  1KH4 A;  3MK1 A;  3WBH A;  4QAX A;  2W5T A;  4LR7 A;  3ED4 A;  5LIA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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