3TG0A

E. coli alkaline phosphatase with bound inorganic phosphate
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
Knots found
sequence length
440
structure length
440
Chain Sequence
NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
molecule keywords Alkaline phosphatase
total genus 164
structure length 440
sequence length 440
chains with identical sequence B, C, D
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3tg0A00
3IGYB 3UNYA 1EW8A 4QAXA 3DYCA 1ALHA 5GOVA 2GLQA 4MHXA 2XR9A 4TN0A 3OT9A 1KH9A 1KH5A 4MIVA 3BDGA 4NWXA 5L0EA 4B56A 3NVLA 3UN5A 4CYSA 2XRGA 1ED8A 2W5TA 1KHKA 4GTYA 1EJJA 2IUCB 2IUCA 1HDHA 1SHNA 4UPIA 3NKNA 4GTXA 2GA3A 1EW9A 5EGEA 3M8YA 1Y6VA 1URAA 3NKQA 3IGZB 2D1GA 4YR1A 4ZGAA 5IJSA 5K4PA 1ALIA 3BDHA 1E33P 4UPLA 4LR2A 3M8ZA 3TWZA 1ZEDA 5DLWA 2W5RA 5LRMA 1O98A 2ZKTA 1E2SP 1FSUA 4LQYA 4GTZA 3CMRA 4CXKA 1EI6A 1ALJA 1E1ZP 3NKMA 1ELYA 4LR8A 3Q3QA 3WAWA 4UPKA 1KH4A 2GSOA 5L0KA 3WBHA 1AJAA 1Y7AA 4FDIA 1ALKA 2W8SA 2W8DA 5LRNA 3NKPA 3T01A 4UOOA 4ZG7A 2W5QA 1AJCA 5EGHA 4LR7A 3WAVA 4LRDA 3LXQA 1ELXA 1ZEFA 4KM4A 4CYRA 1P49A 3NKOA 4UOPA 1AUKA 2X98A 5TJ3A 5DLTA 1SHQA 5L0BA 1EW2A 5LIAA 4CXSA 3T00A 1AJDA 2RH6A 4UPHA 4CXUA 2W5WA 3MK1A 3M8WA 4LR9A 3UO0A 4MY4A 3MK0A 5HRTA 1URBA 3BDFA 1KHLA 1ED9A 1KH7A 3SZYA 4KAVA 5AJ9A 1ANJA 2W5SA 3ED4A 4NWJA 4FDJA 3B5QA 4N7TA 2W5VA 3SZZA 5INHA 3UN3A 5GRRA 3KD8A 3TX0A 1HQAA 2ANHA 1K7HA 5C66A 3UN2A 3BDGB 2QZUA 4GTWA 1N2LA 4KJDA 4ZG6A 1E3CP 1ZEBA 4LRBA 4LRAA 1ANIA 4LREA 4UORA 4KAYA 3WAXA 3T02A 4ZG9A 5LQQA 4KJGA 1AJBA 3WAYA 2W5XA 3DPCA 1KHNA 5KXAA 2IFYA 2GSUA 3A52A 3IDDA 3MK2A 5DLVA 3NKRA 1N2KA 1HJKA 2VQRA 1ELZA 2GSNA 3M7VA 1B8JA 1KHJA 1O99A 2G9YA 4LRCA 3E2DA 1EQJA 5IJQA 4LRFA 3TG0A
chains in the Genus database with same CATH superfamily
3IGYB 3UNYA 1EW8A 4QAXA 3DYCA 1ALHA 5GOVA 2GLQA 4MHXA 2XR9A 4TN0A 3OT9A 1KH9A 1KH5A 4MIVA 3BDGA 4NWXA 5L0EA 4B56A 3NVLA 3UN5A 4CYSA 2XRGA 1ED8A 2W5TA 1KHKA 4GTYA 1EJJA 2IUCB 2IUCA 1HDHA 1SHNA 4UPIA 3NKNA 4GTXA 2GA3A 1EW9A 5EGEA 3M8YA 1Y6VA 1URAA 3NKQA 3IGZB 2D1GA 4YR1A 4ZGAA 5IJSA 5K4PA 1ALIA 3BDHA 1E33P 4UPLA 4LR2A 3M8ZA 3TWZA 1ZEDA 5DLWA 2W5RA 5LRMA 1O98A 2ZKTA 1E2SP 1FSUA 4LQYA 4GTZA 3CMRA 4CXKA 1EI6A 1ALJA 1E1ZP 3NKMA 1ELYA 4LR8A 3Q3QA 3WAWA 4UPKA 1KH4A 2GSOA 5L0KA 3WBHA 1AJAA 1Y7AA 4FDIA 1ALKA 2W8SA 2W8DA 5LRNA 3NKPA 3T01A 4UOOA 4ZG7A 2W5QA 1AJCA 5EGHA 4LR7A 3WAVA 4LRDA 3LXQA 1ELXA 1ZEFA 4KM4A 4CYRA 1P49A 3NKOA 4UOPA 1AUKA 2X98A 5TJ3A 5DLTA 1SHQA 5L0BA 1EW2A 5LIAA 4CXSA 3T00A 1AJDA 2RH6A 4UPHA 4CXUA 2W5WA 3MK1A 3M8WA 4LR9A 3UO0A 4MY4A 3MK0A 5HRTA 1URBA 3BDFA 1KHLA 1ED9A 1KH7A 3SZYA 4KAVA 5AJ9A 1ANJA 2W5SA 3ED4A 4NWJA 4FDJA 3B5QA 4N7TA 2W5VA 3SZZA 5INHA 3UN3A 5GRRA 3KD8A 3TX0A 1HQAA 2ANHA 1K7HA 5C66A 3UN2A 3BDGB 2QZUA 4GTWA 1N2LA 4KJDA 4ZG6A 1E3CP 1ZEBA 4LRBA 4LRAA 1ANIA 4LREA 4UORA 4KAYA 3WAXA 3T02A 4ZG9A 5LQQA 4KJGA 1AJBA 3WAYA 2W5XA 3DPCA 1KHNA 5KXAA 2IFYA 2GSUA 3A52A 3IDDA 3MK2A 5DLVA 3NKRA 1N2KA 1HJKA 2VQRA 1ELZA 2GSNA 3M7VA 1B8JA 1KHJA 1O99A 2G9YA 4LRCA 3E2DA 1EQJA 5IJQA 4LRFA 3TG0A
chains in the Genus database with same CATH topology
3IGYB 3UNYA 1EW8A 4QAXA 3DYCA 1ALHA 5GOVA 2GLQA 4MHXA 2XR9A 4TN0A 3OT9A 1KH9A 1KH5A 4MIVA 3BDGA 4NWXA 5L0EA 4B56A 3NVLA 3UN5A 4CYSA 2XRGA 1ED8A 2W5TA 1KHKA 4GTYA 1EJJA 2IUCB 2IUCA 1HDHA 1SHNA 4UPIA 3NKNA 4GTXA 2GA3A 1EW9A 5EGEA 3M8YA 1Y6VA 1URAA 3NKQA 3IGZB 2D1GA 4YR1A 4ZGAA 5IJSA 5K4PA 1ALIA 3BDHA 1E33P 4UPLA 4LR2A 3M8ZA 3TWZA 1ZEDA 5DLWA 2W5RA 5LRMA 1O98A 2ZKTA 1E2SP 1FSUA 4LQYA 4GTZA 3CMRA 4CXKA 1EI6A 1ALJA 1E1ZP 3NKMA 1ELYA 4LR8A 3Q3QA 3WAWA 4UPKA 1KH4A 2GSOA 5L0KA 3WBHA 1AJAA 1Y7AA 4FDIA 1ALKA 2W8SA 2W8DA 5LRNA 3NKPA 3T01A 4UOOA 4ZG7A 2W5QA 1AJCA 5EGHA 4LR7A 3WAVA 4LRDA 3LXQA 1ELXA 1ZEFA 4KM4A 4CYRA 1P49A 3NKOA 4UOPA 1AUKA 2X98A 5TJ3A 5DLTA 1SHQA 5L0BA 1EW2A 5LIAA 4CXSA 3T00A 1AJDA 2RH6A 4UPHA 4CXUA 2W5WA 3MK1A 3M8WA 4LR9A 3UO0A 4MY4A 3MK0A 5HRTA 1URBA 3BDFA 1KHLA 1ED9A 1KH7A 3SZYA 4KAVA 5AJ9A 1ANJA 2W5SA 3ED4A 4NWJA 4FDJA 3B5QA 4N7TA 2W5VA 3SZZA 5INHA 3UN3A 5GRRA 3KD8A 3TX0A 1HQAA 2ANHA 1K7HA 5C66A 3UN2A 3BDGB 2QZUA 4GTWA 1N2LA 4KJDA 4ZG6A 1E3CP 1ZEBA 4LRBA 4LRAA 1ANIA 4LREA 4UORA 4KAYA 3WAXA 3T02A 4ZG9A 5LQQA 4KJGA 1AJBA 3WAYA 2W5XA 3DPCA 1KHNA 5KXAA 2IFYA 2GSUA 3A52A 3IDDA 3MK2A 5DLVA 3NKRA 1N2KA 1HJKA 2VQRA 1ELZA 2GSNA 3M7VA 1B8JA 1KHJA 1O99A 2G9YA 4LRCA 3E2DA 1EQJA 5IJQA 4LRFA 3TG0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IGY B;  3UNY A;  1EW8 A;  4QAX A;  3DYC A;  1ALH A;  5GOV A;  2GLQ A;  4MHX A;  2XR9 A;  4TN0 A;  3OT9 A;  1KH9 A;  1KH5 A;  4MIV A;  3BDG A;  4NWX A;  5L0E A;  4B56 A;  3NVL A;  3UN5 A;  4CYS A;  2XRG A;  1ED8 A;  2W5T A;  1KHK A;  4GTY A;  1EJJ A;  2IUC B;  2IUC A;  1HDH A;  1SHN A;  4UPI A;  3NKN A;  4GTX A;  2GA3 A;  1EW9 A;  5EGE A;  3M8Y A;  1Y6V A;  1URA A;  3NKQ A;  3IGZ B;  2D1G A;  4YR1 A;  4ZGA A;  5IJS A;  5K4P A;  1ALI A;  3BDH A;  1E33 P;  4UPL A;  4LR2 A;  3M8Z A;  3TWZ A;  1ZED A;  5DLW A;  2W5R A;  5LRM A;  1O98 A;  2ZKT A;  1E2S P;  1FSU A;  4LQY A;  4GTZ A;  3CMR A;  4CXK A;  1EI6 A;  1ALJ A;  1E1Z P;  3NKM A;  1ELY A;  4LR8 A;  3Q3Q A;  3WAW A;  4UPK A;  1KH4 A;  2GSO A;  5L0K A;  3WBH A;  1AJA A;  1Y7A A;  4FDI A;  1ALK A;  2W8S A;  2W8D A;  5LRN A;  3NKP A;  3T01 A;  4UOO A;  4ZG7 A;  2W5Q A;  1AJC A;  5EGH A;  4LR7 A;  3WAV A;  4LRD A;  3LXQ A;  1ELX A;  1ZEF A;  4KM4 A;  4CYR A;  1P49 A;  3NKO A;  4UOP A;  1AUK A;  2X98 A;  5TJ3 A;  5DLT A;  1SHQ A;  5L0B A;  1EW2 A;  5LIA A;  4CXS A;  3T00 A;  1AJD A;  2RH6 A;  4UPH A;  4CXU A;  2W5W A;  3MK1 A;  3M8W A;  4LR9 A;  3UO0 A;  4MY4 A;  3MK0 A;  5HRT A;  1URB A;  3BDF A;  1KHL A;  1ED9 A;  1KH7 A;  3SZY A;  4KAV A;  5AJ9 A;  1ANJ A;  2W5S A;  3ED4 A;  4NWJ A;  4FDJ A;  3B5Q A;  4N7T A;  2W5V A;  3SZZ A;  5INH A;  3UN3 A;  5GRR A;  3KD8 A;  3TX0 A;  1HQA A;  2ANH A;  1K7H A;  5C66 A;  3UN2 A;  3BDG B;  2QZU A;  4GTW A;  1N2L A;  4KJD A;  4ZG6 A;  1E3C P;  1ZEB A;  4LRB A;  4LRA A;  1ANI A;  4LRE A;  4UOR A;  4KAY A;  3WAX A;  3T02 A;  4ZG9 A;  5LQQ A;  4KJG A;  1AJB A;  3WAY A;  2W5X A;  3DPC A;  1KHN A;  5KXA A;  2IFY A;  2GSU A;  3A52 A;  3IDD A;  3MK2 A;  5DLV A;  3NKR A;  1N2K A;  1HJK A;  2VQR A;  1ELZ A;  2GSN A;  3M7V A;  1B8J A;  1KHJ A;  1O99 A;  2G9Y A;  4LRC A;  3E2D A;  1EQJ A;  5IJQ A;  4LRF A;  3TG0 A; 
#chains in the Genus database with same CATH topology
 3IGY B;  3UNY A;  1EW8 A;  4QAX A;  3DYC A;  1ALH A;  5GOV A;  2GLQ A;  4MHX A;  2XR9 A;  4TN0 A;  3OT9 A;  1KH9 A;  1KH5 A;  4MIV A;  3BDG A;  4NWX A;  5L0E A;  4B56 A;  3NVL A;  3UN5 A;  4CYS A;  2XRG A;  1ED8 A;  2W5T A;  1KHK A;  4GTY A;  1EJJ A;  2IUC B;  2IUC A;  1HDH A;  1SHN A;  4UPI A;  3NKN A;  4GTX A;  2GA3 A;  1EW9 A;  5EGE A;  3M8Y A;  1Y6V A;  1URA A;  3NKQ A;  3IGZ B;  2D1G A;  4YR1 A;  4ZGA A;  5IJS A;  5K4P A;  1ALI A;  3BDH A;  1E33 P;  4UPL A;  4LR2 A;  3M8Z A;  3TWZ A;  1ZED A;  5DLW A;  2W5R A;  5LRM A;  1O98 A;  2ZKT A;  1E2S P;  1FSU A;  4LQY A;  4GTZ A;  3CMR A;  4CXK A;  1EI6 A;  1ALJ A;  1E1Z P;  3NKM A;  1ELY A;  4LR8 A;  3Q3Q A;  3WAW A;  4UPK A;  1KH4 A;  2GSO A;  5L0K A;  3WBH A;  1AJA A;  1Y7A A;  4FDI A;  1ALK A;  2W8S A;  2W8D A;  5LRN A;  3NKP A;  3T01 A;  4UOO A;  4ZG7 A;  2W5Q A;  1AJC A;  5EGH A;  4LR7 A;  3WAV A;  4LRD A;  3LXQ A;  1ELX A;  1ZEF A;  4KM4 A;  4CYR A;  1P49 A;  3NKO A;  4UOP A;  1AUK A;  2X98 A;  5TJ3 A;  5DLT A;  1SHQ A;  5L0B A;  1EW2 A;  5LIA A;  4CXS A;  3T00 A;  1AJD A;  2RH6 A;  4UPH A;  4CXU A;  2W5W A;  3MK1 A;  3M8W A;  4LR9 A;  3UO0 A;  4MY4 A;  3MK0 A;  5HRT A;  1URB A;  3BDF A;  1KHL A;  1ED9 A;  1KH7 A;  3SZY A;  4KAV A;  5AJ9 A;  1ANJ A;  2W5S A;  3ED4 A;  4NWJ A;  4FDJ A;  3B5Q A;  4N7T A;  2W5V A;  3SZZ A;  5INH A;  3UN3 A;  5GRR A;  3KD8 A;  3TX0 A;  1HQA A;  2ANH A;  1K7H A;  5C66 A;  3UN2 A;  3BDG B;  2QZU A;  4GTW A;  1N2L A;  4KJD A;  4ZG6 A;  1E3C P;  1ZEB A;  4LRB A;  4LRA A;  1ANI A;  4LRE A;  4UOR A;  4KAY A;  3WAX A;  3T02 A;  4ZG9 A;  5LQQ A;  4KJG A;  1AJB A;  3WAY A;  2W5X A;  3DPC A;  1KHN A;  5KXA A;  2IFY A;  2GSU A;  3A52 A;  3IDD A;  3MK2 A;  5DLV A;  3NKR A;  1N2K A;  1HJK A;  2VQR A;  1ELZ A;  2GSN A;  3M7V A;  1B8J A;  1KHJ A;  1O99 A;  2G9Y A;  4LRC A;  3E2D A;  1EQJ A;  5IJQ A;  4LRF A;  3TG0 A; 
#chains in the Genus database with same CATH homology
 3IGY B;  3UNY A;  1EW8 A;  4QAX A;  3DYC A;  1ALH A;  5GOV A;  2GLQ A;  4MHX A;  2XR9 A;  4TN0 A;  3OT9 A;  1KH9 A;  1KH5 A;  4MIV A;  3BDG A;  4NWX A;  5L0E A;  4B56 A;  3NVL A;  3UN5 A;  4CYS A;  2XRG A;  1ED8 A;  2W5T A;  1KHK A;  4GTY A;  1EJJ A;  2IUC B;  2IUC A;  1HDH A;  1SHN A;  4UPI A;  3NKN A;  4GTX A;  2GA3 A;  1EW9 A;  5EGE A;  3M8Y A;  1Y6V A;  1URA A;  3NKQ A;  3IGZ B;  2D1G A;  4YR1 A;  4ZGA A;  5IJS A;  5K4P A;  1ALI A;  3BDH A;  1E33 P;  4UPL A;  4LR2 A;  3M8Z A;  3TWZ A;  1ZED A;  5DLW A;  2W5R A;  5LRM A;  1O98 A;  2ZKT A;  1E2S P;  1FSU A;  4LQY A;  4GTZ A;  3CMR A;  4CXK A;  1EI6 A;  1ALJ A;  1E1Z P;  3NKM A;  1ELY A;  4LR8 A;  3Q3Q A;  3WAW A;  4UPK A;  1KH4 A;  2GSO A;  5L0K A;  3WBH A;  1AJA A;  1Y7A A;  4FDI A;  1ALK A;  2W8S A;  2W8D A;  5LRN A;  3NKP A;  3T01 A;  4UOO A;  4ZG7 A;  2W5Q A;  1AJC A;  5EGH A;  4LR7 A;  3WAV A;  4LRD A;  3LXQ A;  1ELX A;  1ZEF A;  4KM4 A;  4CYR A;  1P49 A;  3NKO A;  4UOP A;  1AUK A;  2X98 A;  5TJ3 A;  5DLT A;  1SHQ A;  5L0B A;  1EW2 A;  5LIA A;  4CXS A;  3T00 A;  1AJD A;  2RH6 A;  4UPH A;  4CXU A;  2W5W A;  3MK1 A;  3M8W A;  4LR9 A;  3UO0 A;  4MY4 A;  3MK0 A;  5HRT A;  1URB A;  3BDF A;  1KHL A;  1ED9 A;  1KH7 A;  3SZY A;  4KAV A;  5AJ9 A;  1ANJ A;  2W5S A;  3ED4 A;  4NWJ A;  4FDJ A;  3B5Q A;  4N7T A;  2W5V A;  3SZZ A;  5INH A;  3UN3 A;  5GRR A;  3KD8 A;  3TX0 A;  1HQA A;  2ANH A;  1K7H A;  5C66 A;  3UN2 A;  3BDG B;  2QZU A;  4GTW A;  1N2L A;  4KJD A;  4ZG6 A;  1E3C P;  1ZEB A;  4LRB A;  4LRA A;  1ANI A;  4LRE A;  4UOR A;  4KAY A;  3WAX A;  3T02 A;  4ZG9 A;  5LQQ A;  4KJG A;  1AJB A;  3WAY A;  2W5X A;  3DPC A;  1KHN A;  5KXA A;  2IFY A;  2GSU A;  3A52 A;  3IDD A;  3MK2 A;  5DLV A;  3NKR A;  1N2K A;  1HJK A;  2VQR A;  1ELZ A;  2GSN A;  3M7V A;  1B8J A;  1KHJ A;  1O99 A;  2G9Y A;  4LRC A;  3E2D A;  1EQJ A;  5IJQ A;  4LRF A;  3TG0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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