1EJJA

Crystal structural analysis of phosphoglycerate mutase cocrystallized with 3-phosphoglycerate
Total Genus 196
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
196
Knots found
sequence length
508
structure length
508
Chain Sequence
KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PHOSPHOGLYCERATE MUTASE
publication title Structure and mechanism of action of a novel phosphoglycerate mutase from Bacillus stearothermophilus.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
molecule tags Isomerase
total genus 196
structure length 508
sequence length 508
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2000-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ejjA02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1ejjA01
3ED4A 3M8YA 1E2SP 1ANJA 1E1ZP 2IUCA 2VQRA 3NKMA 4LQYA 2G9YA 5TJ3A 1ELZA 3BDGA 1ED8A 1KH5A 3A52A 3TG0A 3IGYB 3WAXA 4KAYA 4LRFA 4NWJA 3WAVA 4LR7A 4GTXA 1EW9A 4KJDA 3BDHA 5L0EA 4FDJA 3WAYA 4UPKA 3MK2A 2XRGA 1AJCA 3MK1A 2ANHA 3NKQA 4KJGA 4LRBA 5EGHA 5L0KA 1KHLA 3OT9A 5LRMA 4CYRA 4UORA 1KHNA 2GSOA 4CXUA 4GTWA 5KXAA 1EW2A 3SZZA 1SHNA 2W8DA 3CMRA 3UN2A 3NKOA 3WAWA 2RH6A 3BDFA 4TN0A 3E2DA 4ZGAA 5HRTA 4KM4A 2W5VA 2XR9A 3NVLA 1KH4A 2QZUA 1P49A 1Y7AA 3UN5A 5L0BA 4MHXA 5IJQA 1ELYA 1O98A 3NKNA 4LR9A 4FDIA 5GRRA 5K4PA 2W5RA 1EQJA 1Y6VA 3WBHA 2D1GA 1ELXA 1EW8A 3SZYA 2ZKTA 4UOPA 4LRAA 1AJAA 5DLTA 4GTYA 5IJSA 4CXKA 4N7TA 5LQQA 3TX0A 4MY4A 4UOOA 1HDHA 4UPIA 4UPHA 1AJDA 4B56A 4ZG6A 2W5WA 3KD8A 5DLWA 3MK0A 1KH7A 2GSUA 1ANIA 3B5QA 5INHA 3NKRA 1E33P 4UPLA 2GSNA 1N2LA 4KAVA 3UNYA 1E3CP 1KHKA 4NWXA 1EJJA 2IFYA 2GA3A 2W5QA 1HQAA 4QAXA 1B8JA 1ED9A 2GLQA 1FSUA 1ALIA 3UN3A 4ZG9A 3NKPA 3Q3QA 2W5XA 5C66A 4LR2A 1SHQA 3DYCA 3M7VA 2X98A 4LREA 1ZEDA 2W5SA 2W5TA 1HJKA 3DPCA 3M8WA 5LIAA 4YR1A 1O99A 3UO0A 4LRDA 4ZG7A 3T01A 3IDDA 1AJBA 5LRNA 1AUKA 2IUCB 5AJ9A 3BDGB 4CYSA 5EGEA 3TWZA 4GTZA 4MIVA 4LR8A 1ALHA 5GOVA 4CXSA 2W8SA 1URBA 1EI6A 3LXQA 1KH9A 1ALKA 1ZEFA 3M8ZA 1KHJA 3T00A 3T02A 4LRCA 1K7HA 1N2KA 1ALJA 3IGZB 1URAA 5DLVA 1ZEBA
chains in the Genus database with same CATH superfamily
3ED4A 3M8YA 1E2SP 1ANJA 1E1ZP 2IUCA 2VQRA 3NKMA 4LQYA 2G9YA 5TJ3A 1ELZA 3BDGA 1ED8A 1KH5A 3A52A 3TG0A 3IGYB 3WAXA 4KAYA 4LRFA 4NWJA 3WAVA 4LR7A 4GTXA 1EW9A 4KJDA 3BDHA 5L0EA 4FDJA 3WAYA 4UPKA 3MK2A 2XRGA 1AJCA 3MK1A 2ANHA 3NKQA 4KJGA 4LRBA 5EGHA 5L0KA 1KHLA 3OT9A 5LRMA 4CYRA 4UORA 1KHNA 2GSOA 4CXUA 4GTWA 5KXAA 1EW2A 3SZZA 1SHNA 2W8DA 3CMRA 3UN2A 3NKOA 3WAWA 2RH6A 3BDFA 4TN0A 3E2DA 4ZGAA 5HRTA 4KM4A 2W5VA 2XR9A 3NVLA 1KH4A 2QZUA 1P49A 1Y7AA 3UN5A 5L0BA 4MHXA 5IJQA 1ELYA 1O98A 3NKNA 4LR9A 4FDIA 5GRRA 5K4PA 2W5RA 1EQJA 1Y6VA 3WBHA 2D1GA 1ELXA 1EW8A 3SZYA 2ZKTA 4UOPA 4LRAA 1AJAA 5DLTA 4GTYA 5IJSA 4CXKA 4N7TA 5LQQA 3TX0A 4MY4A 4UOOA 1HDHA 4UPIA 4UPHA 1AJDA 4B56A 4ZG6A 2W5WA 3KD8A 5DLWA 3MK0A 1KH7A 2GSUA 1ANIA 3B5QA 5INHA 3NKRA 1E33P 4UPLA 2GSNA 1N2LA 4KAVA 3UNYA 1E3CP 1KHKA 4NWXA 1EJJA 2IFYA 2GA3A 2W5QA 1HQAA 4QAXA 1B8JA 1ED9A 2GLQA 1FSUA 1ALIA 3UN3A 4ZG9A 3NKPA 3Q3QA 2W5XA 5C66A 4LR2A 1SHQA 3DYCA 3M7VA 2X98A 4LREA 1ZEDA 2W5SA 2W5TA 1HJKA 3DPCA 3M8WA 5LIAA 4YR1A 1O99A 3UO0A 4LRDA 4ZG7A 3T01A 3IDDA 1AJBA 5LRNA 1AUKA 2IUCB 5AJ9A 3BDGB 4CYSA 5EGEA 3TWZA 4GTZA 4MIVA 4LR8A 1ALHA 5GOVA 4CXSA 2W8SA 1URBA 1EI6A 3LXQA 1KH9A 1ALKA 1ZEFA 3M8ZA 1KHJA 3T00A 3T02A 4LRCA 1K7HA 1N2KA 1ALJA 3IGZB 1URAA 5DLVA 1ZEBA
chains in the Genus database with same CATH topology
3ED4A 3M8YA 1E2SP 1ANJA 1E1ZP 2IUCA 2VQRA 3NKMA 4LQYA 2G9YA 5TJ3A 1ELZA 3BDGA 1ED8A 1KH5A 3A52A 3TG0A 3IGYB 3WAXA 4KAYA 4LRFA 4NWJA 3WAVA 4LR7A 4GTXA 1EW9A 4KJDA 3BDHA 5L0EA 4FDJA 3WAYA 4UPKA 3MK2A 2XRGA 1AJCA 3MK1A 2ANHA 3NKQA 4KJGA 4LRBA 5EGHA 5L0KA 1KHLA 3OT9A 5LRMA 4CYRA 4UORA 1KHNA 2GSOA 4CXUA 4GTWA 5KXAA 1EW2A 3SZZA 1SHNA 2W8DA 3CMRA 3UN2A 3NKOA 3WAWA 2RH6A 3BDFA 4TN0A 3E2DA 4ZGAA 5HRTA 4KM4A 2W5VA 2XR9A 3NVLA 1KH4A 2QZUA 1P49A 1Y7AA 3UN5A 5L0BA 4MHXA 5IJQA 1ELYA 1O98A 3NKNA 4LR9A 4FDIA 5GRRA 5K4PA 2W5RA 1EQJA 1Y6VA 3WBHA 2D1GA 1ELXA 1EW8A 3SZYA 2ZKTA 4UOPA 4LRAA 1AJAA 5DLTA 4GTYA 5IJSA 4CXKA 4N7TA 5LQQA 3TX0A 4MY4A 4UOOA 1HDHA 4UPIA 4UPHA 1AJDA 4B56A 4ZG6A 2W5WA 3KD8A 5DLWA 3MK0A 1KH7A 2GSUA 1ANIA 3B5QA 5INHA 3NKRA 1E33P 4UPLA 2GSNA 1N2LA 4KAVA 3UNYA 1E3CP 1KHKA 4NWXA 1EJJA 2IFYA 2GA3A 2W5QA 1HQAA 4QAXA 1B8JA 1ED9A 2GLQA 1FSUA 1ALIA 3UN3A 4ZG9A 3NKPA 3Q3QA 2W5XA 5C66A 4LR2A 1SHQA 3DYCA 3M7VA 2X98A 4LREA 1ZEDA 2W5SA 2W5TA 1HJKA 3DPCA 3M8WA 5LIAA 4YR1A 1O99A 3UO0A 4LRDA 4ZG7A 3T01A 3IDDA 1AJBA 5LRNA 1AUKA 2IUCB 5AJ9A 3BDGB 4CYSA 5EGEA 3TWZA 4GTZA 4MIVA 4LR8A 1ALHA 5GOVA 4CXSA 2W8SA 1URBA 1EI6A 3LXQA 1KH9A 1ALKA 1ZEFA 3M8ZA 1KHJA 3T00A 3T02A 4LRCA 1K7HA 1N2KA 1ALJA 3IGZB 1URAA 5DLVA 1ZEBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ED4 A;  3M8Y A;  1E2S P;  1ANJ A;  1E1Z P;  2IUC A;  2VQR A;  3NKM A;  4LQY A;  2G9Y A;  5TJ3 A;  1ELZ A;  3BDG A;  1ED8 A;  1KH5 A;  3A52 A;  3TG0 A;  3IGY B;  3WAX A;  4KAY A;  4LRF A;  4NWJ A;  3WAV A;  4LR7 A;  4GTX A;  1EW9 A;  4KJD A;  3BDH A;  5L0E A;  4FDJ A;  3WAY A;  4UPK A;  3MK2 A;  2XRG A;  1AJC A;  3MK1 A;  2ANH A;  3NKQ A;  4KJG A;  4LRB A;  5EGH A;  5L0K A;  1KHL A;  3OT9 A;  5LRM A;  4CYR A;  4UOR A;  1KHN A;  2GSO A;  4CXU A;  4GTW A;  5KXA A;  1EW2 A;  3SZZ A;  1SHN A;  2W8D A;  3CMR A;  3UN2 A;  3NKO A;  3WAW A;  2RH6 A;  3BDF A;  4TN0 A;  3E2D A;  4ZGA A;  5HRT A;  4KM4 A;  2W5V A;  2XR9 A;  3NVL A;  1KH4 A;  2QZU A;  1P49 A;  1Y7A A;  3UN5 A;  5L0B A;  4MHX A;  5IJQ A;  1ELY A;  1O98 A;  3NKN A;  4LR9 A;  4FDI A;  5GRR A;  5K4P A;  2W5R A;  1EQJ A;  1Y6V A;  3WBH A;  2D1G A;  1ELX A;  1EW8 A;  3SZY A;  2ZKT A;  4UOP A;  4LRA A;  1AJA A;  5DLT A;  4GTY A;  5IJS A;  4CXK A;  4N7T A;  5LQQ A;  3TX0 A;  4MY4 A;  4UOO A;  1HDH A;  4UPI A;  4UPH A;  1AJD A;  4B56 A;  4ZG6 A;  2W5W A;  3KD8 A;  5DLW A;  3MK0 A;  1KH7 A;  2GSU A;  1ANI A;  3B5Q A;  5INH A;  3NKR A;  1E33 P;  4UPL A;  2GSN A;  1N2L A;  4KAV A;  3UNY A;  1E3C P;  1KHK A;  4NWX A;  1EJJ A;  2IFY A;  2GA3 A;  2W5Q A;  1HQA A;  4QAX A;  1B8J A;  1ED9 A;  2GLQ A;  1FSU A;  1ALI A;  3UN3 A;  4ZG9 A;  3NKP A;  3Q3Q A;  2W5X A;  5C66 A;  4LR2 A;  1SHQ A;  3DYC A;  3M7V A;  2X98 A;  4LRE A;  1ZED A;  2W5S A;  2W5T A;  1HJK A;  3DPC A;  3M8W A;  5LIA A;  4YR1 A;  1O99 A;  3UO0 A;  4LRD A;  4ZG7 A;  3T01 A;  3IDD A;  1AJB A;  5LRN A;  1AUK A;  2IUC B;  5AJ9 A;  3BDG B;  4CYS A;  5EGE A;  3TWZ A;  4GTZ A;  4MIV A;  4LR8 A;  1ALH A;  5GOV A;  4CXS A;  2W8S A;  1URB A;  1EI6 A;  3LXQ A;  1KH9 A;  1ALK A;  1ZEF A;  3M8Z A;  1KHJ A;  3T00 A;  3T02 A;  4LRC A;  1K7H A;  1N2K A;  1ALJ A;  3IGZ B;  1URA A;  5DLV A;  1ZEB A; 
#chains in the Genus database with same CATH topology
 3ED4 A;  3M8Y A;  1E2S P;  1ANJ A;  1E1Z P;  2IUC A;  2VQR A;  3NKM A;  4LQY A;  2G9Y A;  5TJ3 A;  1ELZ A;  3BDG A;  1ED8 A;  1KH5 A;  3A52 A;  3TG0 A;  3IGY B;  3WAX A;  4KAY A;  4LRF A;  4NWJ A;  3WAV A;  4LR7 A;  4GTX A;  1EW9 A;  4KJD A;  3BDH A;  5L0E A;  4FDJ A;  3WAY A;  4UPK A;  3MK2 A;  2XRG A;  1AJC A;  3MK1 A;  2ANH A;  3NKQ A;  4KJG A;  4LRB A;  5EGH A;  5L0K A;  1KHL A;  3OT9 A;  5LRM A;  4CYR A;  4UOR A;  1KHN A;  2GSO A;  4CXU A;  4GTW A;  5KXA A;  1EW2 A;  3SZZ A;  1SHN A;  2W8D A;  3CMR A;  3UN2 A;  3NKO A;  3WAW A;  2RH6 A;  3BDF A;  4TN0 A;  3E2D A;  4ZGA A;  5HRT A;  4KM4 A;  2W5V A;  2XR9 A;  3NVL A;  1KH4 A;  2QZU A;  1P49 A;  1Y7A A;  3UN5 A;  5L0B A;  4MHX A;  5IJQ A;  1ELY A;  1O98 A;  3NKN A;  4LR9 A;  4FDI A;  5GRR A;  5K4P A;  2W5R A;  1EQJ A;  1Y6V A;  3WBH A;  2D1G A;  1ELX A;  1EW8 A;  3SZY A;  2ZKT A;  4UOP A;  4LRA A;  1AJA A;  5DLT A;  4GTY A;  5IJS A;  4CXK A;  4N7T A;  5LQQ A;  3TX0 A;  4MY4 A;  4UOO A;  1HDH A;  4UPI A;  4UPH A;  1AJD A;  4B56 A;  4ZG6 A;  2W5W A;  3KD8 A;  5DLW A;  3MK0 A;  1KH7 A;  2GSU A;  1ANI A;  3B5Q A;  5INH A;  3NKR A;  1E33 P;  4UPL A;  2GSN A;  1N2L A;  4KAV A;  3UNY A;  1E3C P;  1KHK A;  4NWX A;  1EJJ A;  2IFY A;  2GA3 A;  2W5Q A;  1HQA A;  4QAX A;  1B8J A;  1ED9 A;  2GLQ A;  1FSU A;  1ALI A;  3UN3 A;  4ZG9 A;  3NKP A;  3Q3Q A;  2W5X A;  5C66 A;  4LR2 A;  1SHQ A;  3DYC A;  3M7V A;  2X98 A;  4LRE A;  1ZED A;  2W5S A;  2W5T A;  1HJK A;  3DPC A;  3M8W A;  5LIA A;  4YR1 A;  1O99 A;  3UO0 A;  4LRD A;  4ZG7 A;  3T01 A;  3IDD A;  1AJB A;  5LRN A;  1AUK A;  2IUC B;  5AJ9 A;  3BDG B;  4CYS A;  5EGE A;  3TWZ A;  4GTZ A;  4MIV A;  4LR8 A;  1ALH A;  5GOV A;  4CXS A;  2W8S A;  1URB A;  1EI6 A;  3LXQ A;  1KH9 A;  1ALK A;  1ZEF A;  3M8Z A;  1KHJ A;  3T00 A;  3T02 A;  4LRC A;  1K7H A;  1N2K A;  1ALJ A;  3IGZ B;  1URA A;  5DLV A;  1ZEB A; 
#chains in the Genus database with same CATH homology
 3ED4 A;  3M8Y A;  1E2S P;  1ANJ A;  1E1Z P;  2IUC A;  2VQR A;  3NKM A;  4LQY A;  2G9Y A;  5TJ3 A;  1ELZ A;  3BDG A;  1ED8 A;  1KH5 A;  3A52 A;  3TG0 A;  3IGY B;  3WAX A;  4KAY A;  4LRF A;  4NWJ A;  3WAV A;  4LR7 A;  4GTX A;  1EW9 A;  4KJD A;  3BDH A;  5L0E A;  4FDJ A;  3WAY A;  4UPK A;  3MK2 A;  2XRG A;  1AJC A;  3MK1 A;  2ANH A;  3NKQ A;  4KJG A;  4LRB A;  5EGH A;  5L0K A;  1KHL A;  3OT9 A;  5LRM A;  4CYR A;  4UOR A;  1KHN A;  2GSO A;  4CXU A;  4GTW A;  5KXA A;  1EW2 A;  3SZZ A;  1SHN A;  2W8D A;  3CMR A;  3UN2 A;  3NKO A;  3WAW A;  2RH6 A;  3BDF A;  4TN0 A;  3E2D A;  4ZGA A;  5HRT A;  4KM4 A;  2W5V A;  2XR9 A;  3NVL A;  1KH4 A;  2QZU A;  1P49 A;  1Y7A A;  3UN5 A;  5L0B A;  4MHX A;  5IJQ A;  1ELY A;  1O98 A;  3NKN A;  4LR9 A;  4FDI A;  5GRR A;  5K4P A;  2W5R A;  1EQJ A;  1Y6V A;  3WBH A;  2D1G A;  1ELX A;  1EW8 A;  3SZY A;  2ZKT A;  4UOP A;  4LRA A;  1AJA A;  5DLT A;  4GTY A;  5IJS A;  4CXK A;  4N7T A;  5LQQ A;  3TX0 A;  4MY4 A;  4UOO A;  1HDH A;  4UPI A;  4UPH A;  1AJD A;  4B56 A;  4ZG6 A;  2W5W A;  3KD8 A;  5DLW A;  3MK0 A;  1KH7 A;  2GSU A;  1ANI A;  3B5Q A;  5INH A;  3NKR A;  1E33 P;  4UPL A;  2GSN A;  1N2L A;  4KAV A;  3UNY A;  1E3C P;  1KHK A;  4NWX A;  1EJJ A;  2IFY A;  2GA3 A;  2W5Q A;  1HQA A;  4QAX A;  1B8J A;  1ED9 A;  2GLQ A;  1FSU A;  1ALI A;  3UN3 A;  4ZG9 A;  3NKP A;  3Q3Q A;  2W5X A;  5C66 A;  4LR2 A;  1SHQ A;  3DYC A;  3M7V A;  2X98 A;  4LRE A;  1ZED A;  2W5S A;  2W5T A;  1HJK A;  3DPC A;  3M8W A;  5LIA A;  4YR1 A;  1O99 A;  3UO0 A;  4LRD A;  4ZG7 A;  3T01 A;  3IDD A;  1AJB A;  5LRN A;  1AUK A;  2IUC B;  5AJ9 A;  3BDG B;  4CYS A;  5EGE A;  3TWZ A;  4GTZ A;  4MIV A;  4LR8 A;  1ALH A;  5GOV A;  4CXS A;  2W8S A;  1URB A;  1EI6 A;  3LXQ A;  1KH9 A;  1ALK A;  1ZEF A;  3M8Z A;  1KHJ A;  3T00 A;  3T02 A;  4LRC A;  1K7H A;  1N2K A;  1ALJ A;  3IGZ B;  1URA A;  5DLV A;  1ZEB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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