1EJJA

Crystal structural analysis of phosphoglycerate mutase cocrystallized with 3-phosphoglycerate
Total Genus 196
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
196
Knots found
sequence length
508
structure length
508
Chain Sequence
KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and mechanism of action of a novel phosphoglycerate mutase from Bacillus stearothermophilus.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
molecule tags Isomerase
molecule keywords PHOSPHOGLYCERATE MUTASE
total genus 196
structure length 508
sequence length 508
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2000-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ejjA02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1ejjA01
4LRBA 5EGHA 4ZG7A 3TG0A 4LREA 1ELXA 3DYCA 5IJQA 1ANIA 1ED8A 3MK0A 1Y7AA 5HRTA 3KD8A 1K7HA 1KHJA 2ANHA 2D1GA 1P49A 4YR1A 5GRRA 1ELYA 2W5RA 3M8ZA 4MIVA 5AJ9A 2XRGA 1O98A 4UPIA 4KAVA 1SHQA 1AJBA 4LR8A 4UORA 3UN5A 4GTYA 4NWJA 1E1ZP 1EW9A 1Y6VA 1ZEFA 2IUCB 1HQAA 1E33P 1KH4A 3DPCA 1EI6A 4UPKA 3NKPA 2GSNA 1HDHA 4LRAA 3UO0A 5L0KA 3T00A 5LIAA 3M8YA 2GSUA 2GSOA 1EW8A 1URBA 4TN0A 2GLQA 4ZG6A 1ED9A 1ALKA 3T01A 1AJCA 2W5WA 2W5XA 1E3CP 1FSUA 2W5QA 5L0BA 4LRCA 4QAXA 3UN2A 1AUKA 5L0EA 1KHLA 3M7VA 1ELZA 3UNYA 4CXSA 3BDGB 3MK1A 3IDDA 4FDIA 4LQYA 1ZEBA 2W8SA 2W5VA 4GTXA 1ALIA 4GTZA 3WAYA 1KH9A 3OT9A 4ZGAA 1O99A 2IUCA 1KH7A 4KJGA 1ANJA 3NKQA 2W5SA 4MHXA 3NKOA 4CYSA 2W5TA 3NKRA 4N7TA 1EJJA 4CXUA 1AJDA 3A52A 3WAWA 3IGYB 1E2SP 3WAVA 2RH6A 5LQQA 4KJDA 5C66A 1ALJA 5DLTA 2G9YA 3Q3QA 4NWXA 5IJSA 5DLWA 3WBHA 2W8DA 3SZZA 4UOPA 2XR9A 1KH5A 1AJAA 3WAXA 4UOOA 3CMRA 4KAYA 1B8JA 2IFYA 4GTWA 5DLVA 1ZEDA 5GOVA 4ZG9A 3ED4A 4CYRA 5LRMA 5TJ3A 3UN3A 3B5QA 3NVLA 1EW2A 4LRDA 3T02A 1ALHA 1KHNA 2X98A 1N2LA 1EQJA 4LR9A 3M8WA 3SZYA 1HJKA 1N2KA 1SHNA 3E2DA 4B56A 1KHKA 4MY4A 3TX0A 3NKMA 5K4PA 2ZKTA 2GA3A 2QZUA 3MK2A 2VQRA 4LRFA 4UPLA 4CXKA 5KXAA 5INHA 1URAA 5EGEA 3IGZB 3BDGA 3LXQA 4LR7A 3NKNA 3BDFA 5LRNA 4KM4A 4FDJA 3TWZA 4UPHA 3BDHA 4LR2A
chains in the Genus database with same CATH superfamily
4LRBA 5EGHA 4ZG7A 3TG0A 4LREA 1ELXA 3DYCA 5IJQA 1ANIA 1ED8A 3MK0A 1Y7AA 5HRTA 3KD8A 1K7HA 1KHJA 2ANHA 2D1GA 1P49A 4YR1A 5GRRA 1ELYA 2W5RA 3M8ZA 4MIVA 5AJ9A 2XRGA 1O98A 4UPIA 4KAVA 1SHQA 1AJBA 4LR8A 4UORA 3UN5A 4GTYA 4NWJA 1E1ZP 1EW9A 1Y6VA 1ZEFA 2IUCB 1HQAA 1E33P 1KH4A 3DPCA 1EI6A 4UPKA 3NKPA 2GSNA 1HDHA 4LRAA 3UO0A 5L0KA 3T00A 5LIAA 3M8YA 2GSUA 2GSOA 1EW8A 1URBA 4TN0A 2GLQA 4ZG6A 1ED9A 1ALKA 3T01A 1AJCA 2W5WA 2W5XA 1E3CP 1FSUA 2W5QA 5L0BA 4LRCA 4QAXA 3UN2A 1AUKA 5L0EA 1KHLA 3M7VA 1ELZA 3UNYA 4CXSA 3BDGB 3MK1A 3IDDA 4FDIA 4LQYA 1ZEBA 2W8SA 2W5VA 4GTXA 1ALIA 4GTZA 3WAYA 1KH9A 3OT9A 4ZGAA 1O99A 2IUCA 1KH7A 4KJGA 1ANJA 3NKQA 2W5SA 4MHXA 3NKOA 4CYSA 2W5TA 3NKRA 4N7TA 1EJJA 4CXUA 1AJDA 3A52A 3WAWA 3IGYB 1E2SP 3WAVA 2RH6A 5LQQA 4KJDA 5C66A 1ALJA 5DLTA 2G9YA 3Q3QA 4NWXA 5IJSA 5DLWA 3WBHA 2W8DA 3SZZA 4UOPA 2XR9A 1KH5A 1AJAA 3WAXA 4UOOA 3CMRA 4KAYA 1B8JA 2IFYA 4GTWA 5DLVA 1ZEDA 5GOVA 4ZG9A 3ED4A 4CYRA 5LRMA 5TJ3A 3UN3A 3B5QA 3NVLA 1EW2A 4LRDA 3T02A 1ALHA 1KHNA 2X98A 1N2LA 1EQJA 4LR9A 3M8WA 3SZYA 1HJKA 1N2KA 1SHNA 3E2DA 4B56A 1KHKA 4MY4A 3TX0A 3NKMA 5K4PA 2ZKTA 2GA3A 2QZUA 3MK2A 2VQRA 4LRFA 4UPLA 4CXKA 5KXAA 5INHA 1URAA 5EGEA 3IGZB 3BDGA 3LXQA 4LR7A 3NKNA 3BDFA 5LRNA 4KM4A 4FDJA 3TWZA 4UPHA 3BDHA 4LR2A
chains in the Genus database with same CATH topology
4LRBA 5EGHA 4ZG7A 3TG0A 4LREA 1ELXA 3DYCA 5IJQA 1ANIA 1ED8A 3MK0A 1Y7AA 5HRTA 3KD8A 1K7HA 1KHJA 2ANHA 2D1GA 1P49A 4YR1A 5GRRA 1ELYA 2W5RA 3M8ZA 4MIVA 5AJ9A 2XRGA 1O98A 4UPIA 4KAVA 1SHQA 1AJBA 4LR8A 4UORA 3UN5A 4GTYA 4NWJA 1E1ZP 1EW9A 1Y6VA 1ZEFA 2IUCB 1HQAA 1E33P 1KH4A 3DPCA 1EI6A 4UPKA 3NKPA 2GSNA 1HDHA 4LRAA 3UO0A 5L0KA 3T00A 5LIAA 3M8YA 2GSUA 2GSOA 1EW8A 1URBA 4TN0A 2GLQA 4ZG6A 1ED9A 1ALKA 3T01A 1AJCA 2W5WA 2W5XA 1E3CP 1FSUA 2W5QA 5L0BA 4LRCA 4QAXA 3UN2A 1AUKA 5L0EA 1KHLA 3M7VA 1ELZA 3UNYA 4CXSA 3BDGB 3MK1A 3IDDA 4FDIA 4LQYA 1ZEBA 2W8SA 2W5VA 4GTXA 1ALIA 4GTZA 3WAYA 1KH9A 3OT9A 4ZGAA 1O99A 2IUCA 1KH7A 4KJGA 1ANJA 3NKQA 2W5SA 4MHXA 3NKOA 4CYSA 2W5TA 3NKRA 4N7TA 1EJJA 4CXUA 1AJDA 3A52A 3WAWA 3IGYB 1E2SP 3WAVA 2RH6A 5LQQA 4KJDA 5C66A 1ALJA 5DLTA 2G9YA 3Q3QA 4NWXA 5IJSA 5DLWA 3WBHA 2W8DA 3SZZA 4UOPA 2XR9A 1KH5A 1AJAA 3WAXA 4UOOA 3CMRA 4KAYA 1B8JA 2IFYA 4GTWA 5DLVA 1ZEDA 5GOVA 4ZG9A 3ED4A 4CYRA 5LRMA 5TJ3A 3UN3A 3B5QA 3NVLA 1EW2A 4LRDA 3T02A 1ALHA 1KHNA 2X98A 1N2LA 1EQJA 4LR9A 3M8WA 3SZYA 1HJKA 1N2KA 1SHNA 3E2DA 4B56A 1KHKA 4MY4A 3TX0A 3NKMA 5K4PA 2ZKTA 2GA3A 2QZUA 3MK2A 2VQRA 4LRFA 4UPLA 4CXKA 5KXAA 5INHA 1URAA 5EGEA 3IGZB 3BDGA 3LXQA 4LR7A 3NKNA 3BDFA 5LRNA 4KM4A 4FDJA 3TWZA 4UPHA 3BDHA 4LR2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LRB A;  5EGH A;  4ZG7 A;  3TG0 A;  4LRE A;  1ELX A;  3DYC A;  5IJQ A;  1ANI A;  1ED8 A;  3MK0 A;  1Y7A A;  5HRT A;  3KD8 A;  1K7H A;  1KHJ A;  2ANH A;  2D1G A;  1P49 A;  4YR1 A;  5GRR A;  1ELY A;  2W5R A;  3M8Z A;  4MIV A;  5AJ9 A;  2XRG A;  1O98 A;  4UPI A;  4KAV A;  1SHQ A;  1AJB A;  4LR8 A;  4UOR A;  3UN5 A;  4GTY A;  4NWJ A;  1E1Z P;  1EW9 A;  1Y6V A;  1ZEF A;  2IUC B;  1HQA A;  1E33 P;  1KH4 A;  3DPC A;  1EI6 A;  4UPK A;  3NKP A;  2GSN A;  1HDH A;  4LRA A;  3UO0 A;  5L0K A;  3T00 A;  5LIA A;  3M8Y A;  2GSU A;  2GSO A;  1EW8 A;  1URB A;  4TN0 A;  2GLQ A;  4ZG6 A;  1ED9 A;  1ALK A;  3T01 A;  1AJC A;  2W5W A;  2W5X A;  1E3C P;  1FSU A;  2W5Q A;  5L0B A;  4LRC A;  4QAX A;  3UN2 A;  1AUK A;  5L0E A;  1KHL A;  3M7V A;  1ELZ A;  3UNY A;  4CXS A;  3BDG B;  3MK1 A;  3IDD A;  4FDI A;  4LQY A;  1ZEB A;  2W8S A;  2W5V A;  4GTX A;  1ALI A;  4GTZ A;  3WAY A;  1KH9 A;  3OT9 A;  4ZGA A;  1O99 A;  2IUC A;  1KH7 A;  4KJG A;  1ANJ A;  3NKQ A;  2W5S A;  4MHX A;  3NKO A;  4CYS A;  2W5T A;  3NKR A;  4N7T A;  1EJJ A;  4CXU A;  1AJD A;  3A52 A;  3WAW A;  3IGY B;  1E2S P;  3WAV A;  2RH6 A;  5LQQ A;  4KJD A;  5C66 A;  1ALJ A;  5DLT A;  2G9Y A;  3Q3Q A;  4NWX A;  5IJS A;  5DLW A;  3WBH A;  2W8D A;  3SZZ A;  4UOP A;  2XR9 A;  1KH5 A;  1AJA A;  3WAX A;  4UOO A;  3CMR A;  4KAY A;  1B8J A;  2IFY A;  4GTW A;  5DLV A;  1ZED A;  5GOV A;  4ZG9 A;  3ED4 A;  4CYR A;  5LRM A;  5TJ3 A;  3UN3 A;  3B5Q A;  3NVL A;  1EW2 A;  4LRD A;  3T02 A;  1ALH A;  1KHN A;  2X98 A;  1N2L A;  1EQJ A;  4LR9 A;  3M8W A;  3SZY A;  1HJK A;  1N2K A;  1SHN A;  3E2D A;  4B56 A;  1KHK A;  4MY4 A;  3TX0 A;  3NKM A;  5K4P A;  2ZKT A;  2GA3 A;  2QZU A;  3MK2 A;  2VQR A;  4LRF A;  4UPL A;  4CXK A;  5KXA A;  5INH A;  1URA A;  5EGE A;  3IGZ B;  3BDG A;  3LXQ A;  4LR7 A;  3NKN A;  3BDF A;  5LRN A;  4KM4 A;  4FDJ A;  3TWZ A;  4UPH A;  3BDH A;  4LR2 A; 
#chains in the Genus database with same CATH topology
 4LRB A;  5EGH A;  4ZG7 A;  3TG0 A;  4LRE A;  1ELX A;  3DYC A;  5IJQ A;  1ANI A;  1ED8 A;  3MK0 A;  1Y7A A;  5HRT A;  3KD8 A;  1K7H A;  1KHJ A;  2ANH A;  2D1G A;  1P49 A;  4YR1 A;  5GRR A;  1ELY A;  2W5R A;  3M8Z A;  4MIV A;  5AJ9 A;  2XRG A;  1O98 A;  4UPI A;  4KAV A;  1SHQ A;  1AJB A;  4LR8 A;  4UOR A;  3UN5 A;  4GTY A;  4NWJ A;  1E1Z P;  1EW9 A;  1Y6V A;  1ZEF A;  2IUC B;  1HQA A;  1E33 P;  1KH4 A;  3DPC A;  1EI6 A;  4UPK A;  3NKP A;  2GSN A;  1HDH A;  4LRA A;  3UO0 A;  5L0K A;  3T00 A;  5LIA A;  3M8Y A;  2GSU A;  2GSO A;  1EW8 A;  1URB A;  4TN0 A;  2GLQ A;  4ZG6 A;  1ED9 A;  1ALK A;  3T01 A;  1AJC A;  2W5W A;  2W5X A;  1E3C P;  1FSU A;  2W5Q A;  5L0B A;  4LRC A;  4QAX A;  3UN2 A;  1AUK A;  5L0E A;  1KHL A;  3M7V A;  1ELZ A;  3UNY A;  4CXS A;  3BDG B;  3MK1 A;  3IDD A;  4FDI A;  4LQY A;  1ZEB A;  2W8S A;  2W5V A;  4GTX A;  1ALI A;  4GTZ A;  3WAY A;  1KH9 A;  3OT9 A;  4ZGA A;  1O99 A;  2IUC A;  1KH7 A;  4KJG A;  1ANJ A;  3NKQ A;  2W5S A;  4MHX A;  3NKO A;  4CYS A;  2W5T A;  3NKR A;  4N7T A;  1EJJ A;  4CXU A;  1AJD A;  3A52 A;  3WAW A;  3IGY B;  1E2S P;  3WAV A;  2RH6 A;  5LQQ A;  4KJD A;  5C66 A;  1ALJ A;  5DLT A;  2G9Y A;  3Q3Q A;  4NWX A;  5IJS A;  5DLW A;  3WBH A;  2W8D A;  3SZZ A;  4UOP A;  2XR9 A;  1KH5 A;  1AJA A;  3WAX A;  4UOO A;  3CMR A;  4KAY A;  1B8J A;  2IFY A;  4GTW A;  5DLV A;  1ZED A;  5GOV A;  4ZG9 A;  3ED4 A;  4CYR A;  5LRM A;  5TJ3 A;  3UN3 A;  3B5Q A;  3NVL A;  1EW2 A;  4LRD A;  3T02 A;  1ALH A;  1KHN A;  2X98 A;  1N2L A;  1EQJ A;  4LR9 A;  3M8W A;  3SZY A;  1HJK A;  1N2K A;  1SHN A;  3E2D A;  4B56 A;  1KHK A;  4MY4 A;  3TX0 A;  3NKM A;  5K4P A;  2ZKT A;  2GA3 A;  2QZU A;  3MK2 A;  2VQR A;  4LRF A;  4UPL A;  4CXK A;  5KXA A;  5INH A;  1URA A;  5EGE A;  3IGZ B;  3BDG A;  3LXQ A;  4LR7 A;  3NKN A;  3BDF A;  5LRN A;  4KM4 A;  4FDJ A;  3TWZ A;  4UPH A;  3BDH A;  4LR2 A; 
#chains in the Genus database with same CATH homology
 4LRB A;  5EGH A;  4ZG7 A;  3TG0 A;  4LRE A;  1ELX A;  3DYC A;  5IJQ A;  1ANI A;  1ED8 A;  3MK0 A;  1Y7A A;  5HRT A;  3KD8 A;  1K7H A;  1KHJ A;  2ANH A;  2D1G A;  1P49 A;  4YR1 A;  5GRR A;  1ELY A;  2W5R A;  3M8Z A;  4MIV A;  5AJ9 A;  2XRG A;  1O98 A;  4UPI A;  4KAV A;  1SHQ A;  1AJB A;  4LR8 A;  4UOR A;  3UN5 A;  4GTY A;  4NWJ A;  1E1Z P;  1EW9 A;  1Y6V A;  1ZEF A;  2IUC B;  1HQA A;  1E33 P;  1KH4 A;  3DPC A;  1EI6 A;  4UPK A;  3NKP A;  2GSN A;  1HDH A;  4LRA A;  3UO0 A;  5L0K A;  3T00 A;  5LIA A;  3M8Y A;  2GSU A;  2GSO A;  1EW8 A;  1URB A;  4TN0 A;  2GLQ A;  4ZG6 A;  1ED9 A;  1ALK A;  3T01 A;  1AJC A;  2W5W A;  2W5X A;  1E3C P;  1FSU A;  2W5Q A;  5L0B A;  4LRC A;  4QAX A;  3UN2 A;  1AUK A;  5L0E A;  1KHL A;  3M7V A;  1ELZ A;  3UNY A;  4CXS A;  3BDG B;  3MK1 A;  3IDD A;  4FDI A;  4LQY A;  1ZEB A;  2W8S A;  2W5V A;  4GTX A;  1ALI A;  4GTZ A;  3WAY A;  1KH9 A;  3OT9 A;  4ZGA A;  1O99 A;  2IUC A;  1KH7 A;  4KJG A;  1ANJ A;  3NKQ A;  2W5S A;  4MHX A;  3NKO A;  4CYS A;  2W5T A;  3NKR A;  4N7T A;  1EJJ A;  4CXU A;  1AJD A;  3A52 A;  3WAW A;  3IGY B;  1E2S P;  3WAV A;  2RH6 A;  5LQQ A;  4KJD A;  5C66 A;  1ALJ A;  5DLT A;  2G9Y A;  3Q3Q A;  4NWX A;  5IJS A;  5DLW A;  3WBH A;  2W8D A;  3SZZ A;  4UOP A;  2XR9 A;  1KH5 A;  1AJA A;  3WAX A;  4UOO A;  3CMR A;  4KAY A;  1B8J A;  2IFY A;  4GTW A;  5DLV A;  1ZED A;  5GOV A;  4ZG9 A;  3ED4 A;  4CYR A;  5LRM A;  5TJ3 A;  3UN3 A;  3B5Q A;  3NVL A;  1EW2 A;  4LRD A;  3T02 A;  1ALH A;  1KHN A;  2X98 A;  1N2L A;  1EQJ A;  4LR9 A;  3M8W A;  3SZY A;  1HJK A;  1N2K A;  1SHN A;  3E2D A;  4B56 A;  1KHK A;  4MY4 A;  3TX0 A;  3NKM A;  5K4P A;  2ZKT A;  2GA3 A;  2QZU A;  3MK2 A;  2VQR A;  4LRF A;  4UPL A;  4CXK A;  5KXA A;  5INH A;  1URA A;  5EGE A;  3IGZ B;  3BDG A;  3LXQ A;  4LR7 A;  3NKN A;  3BDF A;  5LRN A;  4KM4 A;  4FDJ A;  3TWZ A;  4UPH A;  3BDH A;  4LR2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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