1EJJA

Crystal structural analysis of phosphoglycerate mutase cocrystallized with 3-phosphoglycerate
Total Genus 196
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
196
Knots found
sequence length
508
structure length
508
Chain Sequence
KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords PHOSPHOGLYCERATE MUTASE
publication title Structure and mechanism of action of a novel phosphoglycerate mutase from Bacillus stearothermophilus.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
total genus 196
structure length 508
sequence length 508
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2000-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ejjA02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1ejjA01
5EGEA 1FSUA 3M8WA 3WAVA 1ZEBA 1EW9A 3UN5A 2W5QA 3DYCA 1EI6A 4KJDA 1ANIA 1KH7A 1ALKA 2RH6A 3B5QA 3T02A 1N2LA 1SHNA 5HRTA 1B8JA 1KHLA 3MK1A 1E1ZP 3WBHA 1Y7AA 3M7VA 4LREA 5DLTA 1AUKA 3TWZA 4LRCA 5C66A 4KM4A 5INHA 1Y6VA 3TG0A 2XRGA 4QAXA 2IUCB 2XR9A 4ZGAA 4UPKA 2VQRA 4TN0A 5DLWA 1KHKA 3TX0A 4YR1A 1AJCA 1ZEFA 1ELXA 3NKNA 3SZZA 1ELZA 3OT9A 4ZG6A 5DLVA 4FDJA 2W5SA 5LRMA 2IUCA 1N2KA 4MY4A 1ZEDA 5LQQA 2IFYA 1URBA 2QZUA 4KAVA 2W8DA 3IGZB 1AJDA 2W5TA 1EQJA 5K4PA 1HDHA 1KH5A 2GSUA 4LRAA 1KH4A 3NKPA 4LR8A 1ALIA 1EW2A 1E3CP 3BDGB 4UOPA 3NKRA 5IJSA 5GOVA 1AJAA 5L0EA 1SHQA 1URAA 2G9YA 1E2SP 4UPHA 4GTXA 3ED4A 1O98A 4CYSA 4MHXA 4CXUA 2GSNA 4NWJA 1P49A 3NKQA 5IJQA 1O99A 2W5WA 3SZYA 4MIVA 1ALHA 2ANHA 1E33P 4ZG9A 4CXKA 1EJJA 3M8YA 5LIAA 1ED8A 3UO0A 3NKOA 1HJKA 4N7TA 5TJ3A 3IDDA 4UPIA 1HQAA 5AJ9A 1ED9A 2GA3A 1AJBA 3NVLA 3DPCA 1KHJA 4B56A 4GTYA 3IGYB 2W5VA 4FDIA 4NWXA 5EGHA 3WAXA 4ZG7A 5LRNA 3LXQA 3Q3QA 3A52A 4GTZA 3M8ZA 2ZKTA 4LR2A 2W5XA 3UN3A 1EW8A 3WAWA 3BDGA 4LR9A 3BDHA 4LRFA 2W5RA 3NKMA 4LR7A 3KD8A 4CXSA 2D1GA 3E2DA 1KH9A 2W8SA 4CYRA 5GRRA 3UNYA 1KHNA 2GLQA 4LRBA 3T00A 2X98A 3BDFA 3T01A 2GSOA 4GTWA 1ALJA 4LQYA 4UPLA 3WAYA 5L0KA 4KAYA 3CMRA 3UN2A 1ELYA 4KJGA 3MK2A 5KXAA 1K7HA 4UOOA 1ANJA 5L0BA 4LRDA 4UORA 3MK0A
chains in the Genus database with same CATH superfamily
5EGEA 1FSUA 3M8WA 3WAVA 1ZEBA 1EW9A 3UN5A 2W5QA 3DYCA 1EI6A 4KJDA 1ANIA 1KH7A 1ALKA 2RH6A 3B5QA 3T02A 1N2LA 1SHNA 5HRTA 1B8JA 1KHLA 3MK1A 1E1ZP 3WBHA 1Y7AA 3M7VA 4LREA 5DLTA 1AUKA 3TWZA 4LRCA 5C66A 4KM4A 5INHA 1Y6VA 3TG0A 2XRGA 4QAXA 2IUCB 2XR9A 4ZGAA 4UPKA 2VQRA 4TN0A 5DLWA 1KHKA 3TX0A 4YR1A 1AJCA 1ZEFA 1ELXA 3NKNA 3SZZA 1ELZA 3OT9A 4ZG6A 5DLVA 4FDJA 2W5SA 5LRMA 2IUCA 1N2KA 4MY4A 1ZEDA 5LQQA 2IFYA 1URBA 2QZUA 4KAVA 2W8DA 3IGZB 1AJDA 2W5TA 1EQJA 5K4PA 1HDHA 1KH5A 2GSUA 4LRAA 1KH4A 3NKPA 4LR8A 1ALIA 1EW2A 1E3CP 3BDGB 4UOPA 3NKRA 5IJSA 5GOVA 1AJAA 5L0EA 1SHQA 1URAA 2G9YA 1E2SP 4UPHA 4GTXA 3ED4A 1O98A 4CYSA 4MHXA 4CXUA 2GSNA 4NWJA 1P49A 3NKQA 5IJQA 1O99A 2W5WA 3SZYA 4MIVA 1ALHA 2ANHA 1E33P 4ZG9A 4CXKA 1EJJA 3M8YA 5LIAA 1ED8A 3UO0A 3NKOA 1HJKA 4N7TA 5TJ3A 3IDDA 4UPIA 1HQAA 5AJ9A 1ED9A 2GA3A 1AJBA 3NVLA 3DPCA 1KHJA 4B56A 4GTYA 3IGYB 2W5VA 4FDIA 4NWXA 5EGHA 3WAXA 4ZG7A 5LRNA 3LXQA 3Q3QA 3A52A 4GTZA 3M8ZA 2ZKTA 4LR2A 2W5XA 3UN3A 1EW8A 3WAWA 3BDGA 4LR9A 3BDHA 4LRFA 2W5RA 3NKMA 4LR7A 3KD8A 4CXSA 2D1GA 3E2DA 1KH9A 2W8SA 4CYRA 5GRRA 3UNYA 1KHNA 2GLQA 4LRBA 3T00A 2X98A 3BDFA 3T01A 2GSOA 4GTWA 1ALJA 4LQYA 4UPLA 3WAYA 5L0KA 4KAYA 3CMRA 3UN2A 1ELYA 4KJGA 3MK2A 5KXAA 1K7HA 4UOOA 1ANJA 5L0BA 4LRDA 4UORA 3MK0A
chains in the Genus database with same CATH topology
5EGEA 1FSUA 3M8WA 3WAVA 1ZEBA 1EW9A 3UN5A 2W5QA 3DYCA 1EI6A 4KJDA 1ANIA 1KH7A 1ALKA 2RH6A 3B5QA 3T02A 1N2LA 1SHNA 5HRTA 1B8JA 1KHLA 3MK1A 1E1ZP 3WBHA 1Y7AA 3M7VA 4LREA 5DLTA 1AUKA 3TWZA 4LRCA 5C66A 4KM4A 5INHA 1Y6VA 3TG0A 2XRGA 4QAXA 2IUCB 2XR9A 4ZGAA 4UPKA 2VQRA 4TN0A 5DLWA 1KHKA 3TX0A 4YR1A 1AJCA 1ZEFA 1ELXA 3NKNA 3SZZA 1ELZA 3OT9A 4ZG6A 5DLVA 4FDJA 2W5SA 5LRMA 2IUCA 1N2KA 4MY4A 1ZEDA 5LQQA 2IFYA 1URBA 2QZUA 4KAVA 2W8DA 3IGZB 1AJDA 2W5TA 1EQJA 5K4PA 1HDHA 1KH5A 2GSUA 4LRAA 1KH4A 3NKPA 4LR8A 1ALIA 1EW2A 1E3CP 3BDGB 4UOPA 3NKRA 5IJSA 5GOVA 1AJAA 5L0EA 1SHQA 1URAA 2G9YA 1E2SP 4UPHA 4GTXA 3ED4A 1O98A 4CYSA 4MHXA 4CXUA 2GSNA 4NWJA 1P49A 3NKQA 5IJQA 1O99A 2W5WA 3SZYA 4MIVA 1ALHA 2ANHA 1E33P 4ZG9A 4CXKA 1EJJA 3M8YA 5LIAA 1ED8A 3UO0A 3NKOA 1HJKA 4N7TA 5TJ3A 3IDDA 4UPIA 1HQAA 5AJ9A 1ED9A 2GA3A 1AJBA 3NVLA 3DPCA 1KHJA 4B56A 4GTYA 3IGYB 2W5VA 4FDIA 4NWXA 5EGHA 3WAXA 4ZG7A 5LRNA 3LXQA 3Q3QA 3A52A 4GTZA 3M8ZA 2ZKTA 4LR2A 2W5XA 3UN3A 1EW8A 3WAWA 3BDGA 4LR9A 3BDHA 4LRFA 2W5RA 3NKMA 4LR7A 3KD8A 4CXSA 2D1GA 3E2DA 1KH9A 2W8SA 4CYRA 5GRRA 3UNYA 1KHNA 2GLQA 4LRBA 3T00A 2X98A 3BDFA 3T01A 2GSOA 4GTWA 1ALJA 4LQYA 4UPLA 3WAYA 5L0KA 4KAYA 3CMRA 3UN2A 1ELYA 4KJGA 3MK2A 5KXAA 1K7HA 4UOOA 1ANJA 5L0BA 4LRDA 4UORA 3MK0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EGE A;  1FSU A;  3M8W A;  3WAV A;  1ZEB A;  1EW9 A;  3UN5 A;  2W5Q A;  3DYC A;  1EI6 A;  4KJD A;  1ANI A;  1KH7 A;  1ALK A;  2RH6 A;  3B5Q A;  3T02 A;  1N2L A;  1SHN A;  5HRT A;  1B8J A;  1KHL A;  3MK1 A;  1E1Z P;  3WBH A;  1Y7A A;  3M7V A;  4LRE A;  5DLT A;  1AUK A;  3TWZ A;  4LRC A;  5C66 A;  4KM4 A;  5INH A;  1Y6V A;  3TG0 A;  2XRG A;  4QAX A;  2IUC B;  2XR9 A;  4ZGA A;  4UPK A;  2VQR A;  4TN0 A;  5DLW A;  1KHK A;  3TX0 A;  4YR1 A;  1AJC A;  1ZEF A;  1ELX A;  3NKN A;  3SZZ A;  1ELZ A;  3OT9 A;  4ZG6 A;  5DLV A;  4FDJ A;  2W5S A;  5LRM A;  2IUC A;  1N2K A;  4MY4 A;  1ZED A;  5LQQ A;  2IFY A;  1URB A;  2QZU A;  4KAV A;  2W8D A;  3IGZ B;  1AJD A;  2W5T A;  1EQJ A;  5K4P A;  1HDH A;  1KH5 A;  2GSU A;  4LRA A;  1KH4 A;  3NKP A;  4LR8 A;  1ALI A;  1EW2 A;  1E3C P;  3BDG B;  4UOP A;  3NKR A;  5IJS A;  5GOV A;  1AJA A;  5L0E A;  1SHQ A;  1URA A;  2G9Y A;  1E2S P;  4UPH A;  4GTX A;  3ED4 A;  1O98 A;  4CYS A;  4MHX A;  4CXU A;  2GSN A;  4NWJ A;  1P49 A;  3NKQ A;  5IJQ A;  1O99 A;  2W5W A;  3SZY A;  4MIV A;  1ALH A;  2ANH A;  1E33 P;  4ZG9 A;  4CXK A;  1EJJ A;  3M8Y A;  5LIA A;  1ED8 A;  3UO0 A;  3NKO A;  1HJK A;  4N7T A;  5TJ3 A;  3IDD A;  4UPI A;  1HQA A;  5AJ9 A;  1ED9 A;  2GA3 A;  1AJB A;  3NVL A;  3DPC A;  1KHJ A;  4B56 A;  4GTY A;  3IGY B;  2W5V A;  4FDI A;  4NWX A;  5EGH A;  3WAX A;  4ZG7 A;  5LRN A;  3LXQ A;  3Q3Q A;  3A52 A;  4GTZ A;  3M8Z A;  2ZKT A;  4LR2 A;  2W5X A;  3UN3 A;  1EW8 A;  3WAW A;  3BDG A;  4LR9 A;  3BDH A;  4LRF A;  2W5R A;  3NKM A;  4LR7 A;  3KD8 A;  4CXS A;  2D1G A;  3E2D A;  1KH9 A;  2W8S A;  4CYR A;  5GRR A;  3UNY A;  1KHN A;  2GLQ A;  4LRB A;  3T00 A;  2X98 A;  3BDF A;  3T01 A;  2GSO A;  4GTW A;  1ALJ A;  4LQY A;  4UPL A;  3WAY A;  5L0K A;  4KAY A;  3CMR A;  3UN2 A;  1ELY A;  4KJG A;  3MK2 A;  5KXA A;  1K7H A;  4UOO A;  1ANJ A;  5L0B A;  4LRD A;  4UOR A;  3MK0 A; 
#chains in the Genus database with same CATH topology
 5EGE A;  1FSU A;  3M8W A;  3WAV A;  1ZEB A;  1EW9 A;  3UN5 A;  2W5Q A;  3DYC A;  1EI6 A;  4KJD A;  1ANI A;  1KH7 A;  1ALK A;  2RH6 A;  3B5Q A;  3T02 A;  1N2L A;  1SHN A;  5HRT A;  1B8J A;  1KHL A;  3MK1 A;  1E1Z P;  3WBH A;  1Y7A A;  3M7V A;  4LRE A;  5DLT A;  1AUK A;  3TWZ A;  4LRC A;  5C66 A;  4KM4 A;  5INH A;  1Y6V A;  3TG0 A;  2XRG A;  4QAX A;  2IUC B;  2XR9 A;  4ZGA A;  4UPK A;  2VQR A;  4TN0 A;  5DLW A;  1KHK A;  3TX0 A;  4YR1 A;  1AJC A;  1ZEF A;  1ELX A;  3NKN A;  3SZZ A;  1ELZ A;  3OT9 A;  4ZG6 A;  5DLV A;  4FDJ A;  2W5S A;  5LRM A;  2IUC A;  1N2K A;  4MY4 A;  1ZED A;  5LQQ A;  2IFY A;  1URB A;  2QZU A;  4KAV A;  2W8D A;  3IGZ B;  1AJD A;  2W5T A;  1EQJ A;  5K4P A;  1HDH A;  1KH5 A;  2GSU A;  4LRA A;  1KH4 A;  3NKP A;  4LR8 A;  1ALI A;  1EW2 A;  1E3C P;  3BDG B;  4UOP A;  3NKR A;  5IJS A;  5GOV A;  1AJA A;  5L0E A;  1SHQ A;  1URA A;  2G9Y A;  1E2S P;  4UPH A;  4GTX A;  3ED4 A;  1O98 A;  4CYS A;  4MHX A;  4CXU A;  2GSN A;  4NWJ A;  1P49 A;  3NKQ A;  5IJQ A;  1O99 A;  2W5W A;  3SZY A;  4MIV A;  1ALH A;  2ANH A;  1E33 P;  4ZG9 A;  4CXK A;  1EJJ A;  3M8Y A;  5LIA A;  1ED8 A;  3UO0 A;  3NKO A;  1HJK A;  4N7T A;  5TJ3 A;  3IDD A;  4UPI A;  1HQA A;  5AJ9 A;  1ED9 A;  2GA3 A;  1AJB A;  3NVL A;  3DPC A;  1KHJ A;  4B56 A;  4GTY A;  3IGY B;  2W5V A;  4FDI A;  4NWX A;  5EGH A;  3WAX A;  4ZG7 A;  5LRN A;  3LXQ A;  3Q3Q A;  3A52 A;  4GTZ A;  3M8Z A;  2ZKT A;  4LR2 A;  2W5X A;  3UN3 A;  1EW8 A;  3WAW A;  3BDG A;  4LR9 A;  3BDH A;  4LRF A;  2W5R A;  3NKM A;  4LR7 A;  3KD8 A;  4CXS A;  2D1G A;  3E2D A;  1KH9 A;  2W8S A;  4CYR A;  5GRR A;  3UNY A;  1KHN A;  2GLQ A;  4LRB A;  3T00 A;  2X98 A;  3BDF A;  3T01 A;  2GSO A;  4GTW A;  1ALJ A;  4LQY A;  4UPL A;  3WAY A;  5L0K A;  4KAY A;  3CMR A;  3UN2 A;  1ELY A;  4KJG A;  3MK2 A;  5KXA A;  1K7H A;  4UOO A;  1ANJ A;  5L0B A;  4LRD A;  4UOR A;  3MK0 A; 
#chains in the Genus database with same CATH homology
 5EGE A;  1FSU A;  3M8W A;  3WAV A;  1ZEB A;  1EW9 A;  3UN5 A;  2W5Q A;  3DYC A;  1EI6 A;  4KJD A;  1ANI A;  1KH7 A;  1ALK A;  2RH6 A;  3B5Q A;  3T02 A;  1N2L A;  1SHN A;  5HRT A;  1B8J A;  1KHL A;  3MK1 A;  1E1Z P;  3WBH A;  1Y7A A;  3M7V A;  4LRE A;  5DLT A;  1AUK A;  3TWZ A;  4LRC A;  5C66 A;  4KM4 A;  5INH A;  1Y6V A;  3TG0 A;  2XRG A;  4QAX A;  2IUC B;  2XR9 A;  4ZGA A;  4UPK A;  2VQR A;  4TN0 A;  5DLW A;  1KHK A;  3TX0 A;  4YR1 A;  1AJC A;  1ZEF A;  1ELX A;  3NKN A;  3SZZ A;  1ELZ A;  3OT9 A;  4ZG6 A;  5DLV A;  4FDJ A;  2W5S A;  5LRM A;  2IUC A;  1N2K A;  4MY4 A;  1ZED A;  5LQQ A;  2IFY A;  1URB A;  2QZU A;  4KAV A;  2W8D A;  3IGZ B;  1AJD A;  2W5T A;  1EQJ A;  5K4P A;  1HDH A;  1KH5 A;  2GSU A;  4LRA A;  1KH4 A;  3NKP A;  4LR8 A;  1ALI A;  1EW2 A;  1E3C P;  3BDG B;  4UOP A;  3NKR A;  5IJS A;  5GOV A;  1AJA A;  5L0E A;  1SHQ A;  1URA A;  2G9Y A;  1E2S P;  4UPH A;  4GTX A;  3ED4 A;  1O98 A;  4CYS A;  4MHX A;  4CXU A;  2GSN A;  4NWJ A;  1P49 A;  3NKQ A;  5IJQ A;  1O99 A;  2W5W A;  3SZY A;  4MIV A;  1ALH A;  2ANH A;  1E33 P;  4ZG9 A;  4CXK A;  1EJJ A;  3M8Y A;  5LIA A;  1ED8 A;  3UO0 A;  3NKO A;  1HJK A;  4N7T A;  5TJ3 A;  3IDD A;  4UPI A;  1HQA A;  5AJ9 A;  1ED9 A;  2GA3 A;  1AJB A;  3NVL A;  3DPC A;  1KHJ A;  4B56 A;  4GTY A;  3IGY B;  2W5V A;  4FDI A;  4NWX A;  5EGH A;  3WAX A;  4ZG7 A;  5LRN A;  3LXQ A;  3Q3Q A;  3A52 A;  4GTZ A;  3M8Z A;  2ZKT A;  4LR2 A;  2W5X A;  3UN3 A;  1EW8 A;  3WAW A;  3BDG A;  4LR9 A;  3BDH A;  4LRF A;  2W5R A;  3NKM A;  4LR7 A;  3KD8 A;  4CXS A;  2D1G A;  3E2D A;  1KH9 A;  2W8S A;  4CYR A;  5GRR A;  3UNY A;  1KHN A;  2GLQ A;  4LRB A;  3T00 A;  2X98 A;  3BDF A;  3T01 A;  2GSO A;  4GTW A;  1ALJ A;  4LQY A;  4UPL A;  3WAY A;  5L0K A;  4KAY A;  3CMR A;  3UN2 A;  1ELY A;  4KJG A;  3MK2 A;  5KXA A;  1K7H A;  4UOO A;  1ANJ A;  5L0B A;  4LRD A;  4UOR A;  3MK0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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