1O98A

1.4a crystal structure of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
Knots found
sequence length
509
structure length
509
Chain Sequence
SKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE
publication title Insights Into the Catalytic Mechanism of Cofactor-Independent Phosphoglycerate Mutase from X-Ray Crystallography, Simulated Dynamics and Molecular Modeling
pubmed doi rcsb
source organism Bacillus stearothermophilus
molecule tags Isomerase
total genus 199
structure length 509
sequence length 509
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2002-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1o98A02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1o98A01
1ALHA 3TX0A 5INHA 2XRGA 1URAA 2W5SA 3E2DA 3WAVA 1K7HA 1KH9A 1B8JA 2W8SA 5DLWA 5AJ9A 2X98A 1ED8A 4FDJA 5L0BA 1AJDA 5K4PA 1AJCA 4LRFA 5EGEA 5LIAA 4KJGA 1AUKA 4TN0A 4UPHA 3BDFA 4CXUA 1HDHA 2GSNA 1URBA 1ALKA 3T01A 4ZGAA 3MK1A 3NKQA 1ELYA 1Y7AA 3WAXA 4QAXA 4LQYA 5KXAA 4LREA 4LR8A 3KD8A 3M8ZA 3NKMA 4N7TA 4NWJA 1KHNA 1E1ZP 3NKPA 3OT9A 2ANHA 1ZEFA 1ALJA 2W5VA 1ALIA 1EW2A 3B5QA 4UPIA 3UN2A 5DLTA 3T00A 4UPLA 4ZG9A 2XR9A 5DLVA 2GSUA 1ANIA 3BDHA 3DYCA 1N2KA 1KH5A 3DPCA 3IDDA 3NKRA 2RH6A 3UNYA 1EQJA 5HRTA 2W5TA 1FSUA 4FDIA 4MY4A 5LRNA 2GLQA 5TJ3A 3NKOA 5IJSA 4ZG7A 1O99A 3NKNA 4MHXA 1P49A 4LR9A 5GRRA 3ED4A 2W8DA 5GOVA 2GSOA 1ZEDA 4CXKA 1HQAA 3SZYA 1AJAA 2D1GA 2IUCA 2IUCB 4NWXA 4KAVA 1ELZA 3IGZB 5L0KA 1E2SP 3BDGB 4GTZA 3UO0A 3CMRA 4GTXA 2IFYA 3WBHA 1E3CP 5L0EA 2W5XA 3SZZA 1O98A 4LRDA 1EW8A 1AJBA 5LQQA 3M8WA 4CXSA 2W5RA 2VQRA 4UPKA 4UOOA 3Q3QA 2W5QA 4LRCA 1ZEBA 4LRAA 4GTYA 4KJDA 2GA3A 1ELXA 5IJQA 1EJJA 1EI6A 3A52A 3NVLA 5EGHA 1E33P 3TWZA 4B56A 4YR1A 4UORA 1EW9A 3WAWA 4CYRA 4MIVA 1Y6VA 3BDGA 4LR2A 3T02A 1ANJA 4LR7A 3MK0A 5LRMA 1SHNA 4CYSA 4KAYA 1HJKA 1KH7A 4UOPA 3LXQA 1N2LA 1KH4A 4GTWA 2QZUA 2W5WA 1KHJA 3MK2A 3WAYA 3M7VA 2G9YA 3UN3A 3TG0A 3M8YA 1SHQA 1ED9A 1KHLA 2ZKTA 3IGYB 3UN5A 4ZG6A 4KM4A 1KHKA 4LRBA 5C66A
chains in the Genus database with same CATH superfamily
1ALHA 3TX0A 5INHA 2XRGA 1URAA 2W5SA 3E2DA 3WAVA 1K7HA 1KH9A 1B8JA 2W8SA 5DLWA 5AJ9A 2X98A 1ED8A 4FDJA 5L0BA 1AJDA 5K4PA 1AJCA 4LRFA 5EGEA 5LIAA 4KJGA 1AUKA 4TN0A 4UPHA 3BDFA 4CXUA 1HDHA 2GSNA 1URBA 1ALKA 3T01A 4ZGAA 3MK1A 3NKQA 1ELYA 1Y7AA 3WAXA 4QAXA 4LQYA 5KXAA 4LREA 4LR8A 3KD8A 3M8ZA 3NKMA 4N7TA 4NWJA 1KHNA 1E1ZP 3NKPA 3OT9A 2ANHA 1ZEFA 1ALJA 2W5VA 1ALIA 1EW2A 3B5QA 4UPIA 3UN2A 5DLTA 3T00A 4UPLA 4ZG9A 2XR9A 5DLVA 2GSUA 1ANIA 3BDHA 3DYCA 1N2KA 1KH5A 3DPCA 3IDDA 3NKRA 2RH6A 3UNYA 1EQJA 5HRTA 2W5TA 1FSUA 4FDIA 4MY4A 5LRNA 2GLQA 5TJ3A 3NKOA 5IJSA 4ZG7A 1O99A 3NKNA 4MHXA 1P49A 4LR9A 5GRRA 3ED4A 2W8DA 5GOVA 2GSOA 1ZEDA 4CXKA 1HQAA 3SZYA 1AJAA 2D1GA 2IUCA 2IUCB 4NWXA 4KAVA 1ELZA 3IGZB 5L0KA 1E2SP 3BDGB 4GTZA 3UO0A 3CMRA 4GTXA 2IFYA 3WBHA 1E3CP 5L0EA 2W5XA 3SZZA 1O98A 4LRDA 1EW8A 1AJBA 5LQQA 3M8WA 4CXSA 2W5RA 2VQRA 4UPKA 4UOOA 3Q3QA 2W5QA 4LRCA 1ZEBA 4LRAA 4GTYA 4KJDA 2GA3A 1ELXA 5IJQA 1EJJA 1EI6A 3A52A 3NVLA 5EGHA 1E33P 3TWZA 4B56A 4YR1A 4UORA 1EW9A 3WAWA 4CYRA 4MIVA 1Y6VA 3BDGA 4LR2A 3T02A 1ANJA 4LR7A 3MK0A 5LRMA 1SHNA 4CYSA 4KAYA 1HJKA 1KH7A 4UOPA 3LXQA 1N2LA 1KH4A 4GTWA 2QZUA 2W5WA 1KHJA 3MK2A 3WAYA 3M7VA 2G9YA 3UN3A 3TG0A 3M8YA 1SHQA 1ED9A 1KHLA 2ZKTA 3IGYB 3UN5A 4ZG6A 4KM4A 1KHKA 4LRBA 5C66A
chains in the Genus database with same CATH topology
1ALHA 3TX0A 5INHA 2XRGA 1URAA 2W5SA 3E2DA 3WAVA 1K7HA 1KH9A 1B8JA 2W8SA 5DLWA 5AJ9A 2X98A 1ED8A 4FDJA 5L0BA 1AJDA 5K4PA 1AJCA 4LRFA 5EGEA 5LIAA 4KJGA 1AUKA 4TN0A 4UPHA 3BDFA 4CXUA 1HDHA 2GSNA 1URBA 1ALKA 3T01A 4ZGAA 3MK1A 3NKQA 1ELYA 1Y7AA 3WAXA 4QAXA 4LQYA 5KXAA 4LREA 4LR8A 3KD8A 3M8ZA 3NKMA 4N7TA 4NWJA 1KHNA 1E1ZP 3NKPA 3OT9A 2ANHA 1ZEFA 1ALJA 2W5VA 1ALIA 1EW2A 3B5QA 4UPIA 3UN2A 5DLTA 3T00A 4UPLA 4ZG9A 2XR9A 5DLVA 2GSUA 1ANIA 3BDHA 3DYCA 1N2KA 1KH5A 3DPCA 3IDDA 3NKRA 2RH6A 3UNYA 1EQJA 5HRTA 2W5TA 1FSUA 4FDIA 4MY4A 5LRNA 2GLQA 5TJ3A 3NKOA 5IJSA 4ZG7A 1O99A 3NKNA 4MHXA 1P49A 4LR9A 5GRRA 3ED4A 2W8DA 5GOVA 2GSOA 1ZEDA 4CXKA 1HQAA 3SZYA 1AJAA 2D1GA 2IUCA 2IUCB 4NWXA 4KAVA 1ELZA 3IGZB 5L0KA 1E2SP 3BDGB 4GTZA 3UO0A 3CMRA 4GTXA 2IFYA 3WBHA 1E3CP 5L0EA 2W5XA 3SZZA 1O98A 4LRDA 1EW8A 1AJBA 5LQQA 3M8WA 4CXSA 2W5RA 2VQRA 4UPKA 4UOOA 3Q3QA 2W5QA 4LRCA 1ZEBA 4LRAA 4GTYA 4KJDA 2GA3A 1ELXA 5IJQA 1EJJA 1EI6A 3A52A 3NVLA 5EGHA 1E33P 3TWZA 4B56A 4YR1A 4UORA 1EW9A 3WAWA 4CYRA 4MIVA 1Y6VA 3BDGA 4LR2A 3T02A 1ANJA 4LR7A 3MK0A 5LRMA 1SHNA 4CYSA 4KAYA 1HJKA 1KH7A 4UOPA 3LXQA 1N2LA 1KH4A 4GTWA 2QZUA 2W5WA 1KHJA 3MK2A 3WAYA 3M7VA 2G9YA 3UN3A 3TG0A 3M8YA 1SHQA 1ED9A 1KHLA 2ZKTA 3IGYB 3UN5A 4ZG6A 4KM4A 1KHKA 4LRBA 5C66A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ALH A;  3TX0 A;  5INH A;  2XRG A;  1URA A;  2W5S A;  3E2D A;  3WAV A;  1K7H A;  1KH9 A;  1B8J A;  2W8S A;  5DLW A;  5AJ9 A;  2X98 A;  1ED8 A;  4FDJ A;  5L0B A;  1AJD A;  5K4P A;  1AJC A;  4LRF A;  5EGE A;  5LIA A;  4KJG A;  1AUK A;  4TN0 A;  4UPH A;  3BDF A;  4CXU A;  1HDH A;  2GSN A;  1URB A;  1ALK A;  3T01 A;  4ZGA A;  3MK1 A;  3NKQ A;  1ELY A;  1Y7A A;  3WAX A;  4QAX A;  4LQY A;  5KXA A;  4LRE A;  4LR8 A;  3KD8 A;  3M8Z A;  3NKM A;  4N7T A;  4NWJ A;  1KHN A;  1E1Z P;  3NKP A;  3OT9 A;  2ANH A;  1ZEF A;  1ALJ A;  2W5V A;  1ALI A;  1EW2 A;  3B5Q A;  4UPI A;  3UN2 A;  5DLT A;  3T00 A;  4UPL A;  4ZG9 A;  2XR9 A;  5DLV A;  2GSU A;  1ANI A;  3BDH A;  3DYC A;  1N2K A;  1KH5 A;  3DPC A;  3IDD A;  3NKR A;  2RH6 A;  3UNY A;  1EQJ A;  5HRT A;  2W5T A;  1FSU A;  4FDI A;  4MY4 A;  5LRN A;  2GLQ A;  5TJ3 A;  3NKO A;  5IJS A;  4ZG7 A;  1O99 A;  3NKN A;  4MHX A;  1P49 A;  4LR9 A;  5GRR A;  3ED4 A;  2W8D A;  5GOV A;  2GSO A;  1ZED A;  4CXK A;  1HQA A;  3SZY A;  1AJA A;  2D1G A;  2IUC A;  2IUC B;  4NWX A;  4KAV A;  1ELZ A;  3IGZ B;  5L0K A;  1E2S P;  3BDG B;  4GTZ A;  3UO0 A;  3CMR A;  4GTX A;  2IFY A;  3WBH A;  1E3C P;  5L0E A;  2W5X A;  3SZZ A;  1O98 A;  4LRD A;  1EW8 A;  1AJB A;  5LQQ A;  3M8W A;  4CXS A;  2W5R A;  2VQR A;  4UPK A;  4UOO A;  3Q3Q A;  2W5Q A;  4LRC A;  1ZEB A;  4LRA A;  4GTY A;  4KJD A;  2GA3 A;  1ELX A;  5IJQ A;  1EJJ A;  1EI6 A;  3A52 A;  3NVL A;  5EGH A;  1E33 P;  3TWZ A;  4B56 A;  4YR1 A;  4UOR A;  1EW9 A;  3WAW A;  4CYR A;  4MIV A;  1Y6V A;  3BDG A;  4LR2 A;  3T02 A;  1ANJ A;  4LR7 A;  3MK0 A;  5LRM A;  1SHN A;  4CYS A;  4KAY A;  1HJK A;  1KH7 A;  4UOP A;  3LXQ A;  1N2L A;  1KH4 A;  4GTW A;  2QZU A;  2W5W A;  1KHJ A;  3MK2 A;  3WAY A;  3M7V A;  2G9Y A;  3UN3 A;  3TG0 A;  3M8Y A;  1SHQ A;  1ED9 A;  1KHL A;  2ZKT A;  3IGY B;  3UN5 A;  4ZG6 A;  4KM4 A;  1KHK A;  4LRB A;  5C66 A; 
#chains in the Genus database with same CATH topology
 1ALH A;  3TX0 A;  5INH A;  2XRG A;  1URA A;  2W5S A;  3E2D A;  3WAV A;  1K7H A;  1KH9 A;  1B8J A;  2W8S A;  5DLW A;  5AJ9 A;  2X98 A;  1ED8 A;  4FDJ A;  5L0B A;  1AJD A;  5K4P A;  1AJC A;  4LRF A;  5EGE A;  5LIA A;  4KJG A;  1AUK A;  4TN0 A;  4UPH A;  3BDF A;  4CXU A;  1HDH A;  2GSN A;  1URB A;  1ALK A;  3T01 A;  4ZGA A;  3MK1 A;  3NKQ A;  1ELY A;  1Y7A A;  3WAX A;  4QAX A;  4LQY A;  5KXA A;  4LRE A;  4LR8 A;  3KD8 A;  3M8Z A;  3NKM A;  4N7T A;  4NWJ A;  1KHN A;  1E1Z P;  3NKP A;  3OT9 A;  2ANH A;  1ZEF A;  1ALJ A;  2W5V A;  1ALI A;  1EW2 A;  3B5Q A;  4UPI A;  3UN2 A;  5DLT A;  3T00 A;  4UPL A;  4ZG9 A;  2XR9 A;  5DLV A;  2GSU A;  1ANI A;  3BDH A;  3DYC A;  1N2K A;  1KH5 A;  3DPC A;  3IDD A;  3NKR A;  2RH6 A;  3UNY A;  1EQJ A;  5HRT A;  2W5T A;  1FSU A;  4FDI A;  4MY4 A;  5LRN A;  2GLQ A;  5TJ3 A;  3NKO A;  5IJS A;  4ZG7 A;  1O99 A;  3NKN A;  4MHX A;  1P49 A;  4LR9 A;  5GRR A;  3ED4 A;  2W8D A;  5GOV A;  2GSO A;  1ZED A;  4CXK A;  1HQA A;  3SZY A;  1AJA A;  2D1G A;  2IUC A;  2IUC B;  4NWX A;  4KAV A;  1ELZ A;  3IGZ B;  5L0K A;  1E2S P;  3BDG B;  4GTZ A;  3UO0 A;  3CMR A;  4GTX A;  2IFY A;  3WBH A;  1E3C P;  5L0E A;  2W5X A;  3SZZ A;  1O98 A;  4LRD A;  1EW8 A;  1AJB A;  5LQQ A;  3M8W A;  4CXS A;  2W5R A;  2VQR A;  4UPK A;  4UOO A;  3Q3Q A;  2W5Q A;  4LRC A;  1ZEB A;  4LRA A;  4GTY A;  4KJD A;  2GA3 A;  1ELX A;  5IJQ A;  1EJJ A;  1EI6 A;  3A52 A;  3NVL A;  5EGH A;  1E33 P;  3TWZ A;  4B56 A;  4YR1 A;  4UOR A;  1EW9 A;  3WAW A;  4CYR A;  4MIV A;  1Y6V A;  3BDG A;  4LR2 A;  3T02 A;  1ANJ A;  4LR7 A;  3MK0 A;  5LRM A;  1SHN A;  4CYS A;  4KAY A;  1HJK A;  1KH7 A;  4UOP A;  3LXQ A;  1N2L A;  1KH4 A;  4GTW A;  2QZU A;  2W5W A;  1KHJ A;  3MK2 A;  3WAY A;  3M7V A;  2G9Y A;  3UN3 A;  3TG0 A;  3M8Y A;  1SHQ A;  1ED9 A;  1KHL A;  2ZKT A;  3IGY B;  3UN5 A;  4ZG6 A;  4KM4 A;  1KHK A;  4LRB A;  5C66 A; 
#chains in the Genus database with same CATH homology
 1ALH A;  3TX0 A;  5INH A;  2XRG A;  1URA A;  2W5S A;  3E2D A;  3WAV A;  1K7H A;  1KH9 A;  1B8J A;  2W8S A;  5DLW A;  5AJ9 A;  2X98 A;  1ED8 A;  4FDJ A;  5L0B A;  1AJD A;  5K4P A;  1AJC A;  4LRF A;  5EGE A;  5LIA A;  4KJG A;  1AUK A;  4TN0 A;  4UPH A;  3BDF A;  4CXU A;  1HDH A;  2GSN A;  1URB A;  1ALK A;  3T01 A;  4ZGA A;  3MK1 A;  3NKQ A;  1ELY A;  1Y7A A;  3WAX A;  4QAX A;  4LQY A;  5KXA A;  4LRE A;  4LR8 A;  3KD8 A;  3M8Z A;  3NKM A;  4N7T A;  4NWJ A;  1KHN A;  1E1Z P;  3NKP A;  3OT9 A;  2ANH A;  1ZEF A;  1ALJ A;  2W5V A;  1ALI A;  1EW2 A;  3B5Q A;  4UPI A;  3UN2 A;  5DLT A;  3T00 A;  4UPL A;  4ZG9 A;  2XR9 A;  5DLV A;  2GSU A;  1ANI A;  3BDH A;  3DYC A;  1N2K A;  1KH5 A;  3DPC A;  3IDD A;  3NKR A;  2RH6 A;  3UNY A;  1EQJ A;  5HRT A;  2W5T A;  1FSU A;  4FDI A;  4MY4 A;  5LRN A;  2GLQ A;  5TJ3 A;  3NKO A;  5IJS A;  4ZG7 A;  1O99 A;  3NKN A;  4MHX A;  1P49 A;  4LR9 A;  5GRR A;  3ED4 A;  2W8D A;  5GOV A;  2GSO A;  1ZED A;  4CXK A;  1HQA A;  3SZY A;  1AJA A;  2D1G A;  2IUC A;  2IUC B;  4NWX A;  4KAV A;  1ELZ A;  3IGZ B;  5L0K A;  1E2S P;  3BDG B;  4GTZ A;  3UO0 A;  3CMR A;  4GTX A;  2IFY A;  3WBH A;  1E3C P;  5L0E A;  2W5X A;  3SZZ A;  1O98 A;  4LRD A;  1EW8 A;  1AJB A;  5LQQ A;  3M8W A;  4CXS A;  2W5R A;  2VQR A;  4UPK A;  4UOO A;  3Q3Q A;  2W5Q A;  4LRC A;  1ZEB A;  4LRA A;  4GTY A;  4KJD A;  2GA3 A;  1ELX A;  5IJQ A;  1EJJ A;  1EI6 A;  3A52 A;  3NVL A;  5EGH A;  1E33 P;  3TWZ A;  4B56 A;  4YR1 A;  4UOR A;  1EW9 A;  3WAW A;  4CYR A;  4MIV A;  1Y6V A;  3BDG A;  4LR2 A;  3T02 A;  1ANJ A;  4LR7 A;  3MK0 A;  5LRM A;  1SHN A;  4CYS A;  4KAY A;  1HJK A;  1KH7 A;  4UOP A;  3LXQ A;  1N2L A;  1KH4 A;  4GTW A;  2QZU A;  2W5W A;  1KHJ A;  3MK2 A;  3WAY A;  3M7V A;  2G9Y A;  3UN3 A;  3TG0 A;  3M8Y A;  1SHQ A;  1ED9 A;  1KHL A;  2ZKT A;  3IGY B;  3UN5 A;  4ZG6 A;  4KM4 A;  1KHK A;  4LRB A;  5C66 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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