1O98A

1.4a crystal structure of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
Knots found
sequence length
509
structure length
509
Chain Sequence
SKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Insights Into the Catalytic Mechanism of Cofactor-Independent Phosphoglycerate Mutase from X-Ray Crystallography, Simulated Dynamics and Molecular Modeling
pubmed doi rcsb
source organism Bacillus stearothermophilus
molecule tags Isomerase
molecule keywords 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE
total genus 199
structure length 509
sequence length 509
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2002-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1o98A02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1o98A01
3E2DA 3Q3QA 4KAYA 5GOVA 2ANHA 3CMRA 5EGHA 3NKPA 4LRAA 1SHNA 3IDDA 5L0KA 1ALIA 1K7HA 3BDGA 3UN3A 2XR9A 1ELZA 4LRBA 3UN5A 1KH9A 3BDHA 1KH7A 5DLWA 3ED4A 3WAXA 5GRRA 3M8YA 3NKQA 1Y7AA 1O98A 2W8DA 1O99A 3KD8A 3NKRA 4GTYA 2W5XA 1AJCA 3IGYB 4TN0A 4UPLA 4UOOA 1HDHA 3TWZA 3M7VA 1ED8A 3NKOA 2QZUA 2GSOA 1KH5A 4GTZA 4LREA 5LRMA 1ED9A 1N2KA 3DPCA 1AJBA 3DYCA 3MK2A 4FDJA 3TX0A 4ZG7A 4ZGAA 5HRTA 1N2LA 1ANJA 1KH4A 1URAA 2GLQA 3UN2A 4CXKA 1ZEFA 4CYRA 5L0BA 3A52A 2D1GA 1KHLA 1KHJA 1ZEDA 3T00A 5K4PA 1E2SP 4QAXA 1KHNA 4NWXA 2IUCA 3MK0A 2W5SA 4LRCA 4UPIA 3NKMA 2RH6A 1ZEBA 4UPHA 1AUKA 3SZYA 4MHXA 4B56A 2IUCB 4YR1A 3NKNA 3B5QA 3T01A 5INHA 4CYSA 1URBA 4CXUA 2G9YA 4GTWA 2IFYA 1ELXA 5DLVA 1HQAA 4UPKA 1E1ZP 5C66A 3TG0A 1EQJA 4LR8A 1HJKA 3BDGB 2W5QA 1AJAA 2XRGA 5DLTA 2W5WA 4FDIA 2ZKTA 4KM4A 5LQQA 3WAYA 1EW8A 4LR7A 1AJDA 3M8WA 3UNYA 3SZZA 4N7TA 4MIVA 5LIAA 1EW2A 2W8SA 3IGZB 4LR9A 4KJGA 4LRFA 4UORA 3WBHA 2W5VA 5IJQA 2GSNA 1B8JA 2VQRA 1SHQA 3LXQA 1EI6A 3MK1A 4LR2A 1ELYA 5AJ9A 4ZG6A 2W5RA 1ALJA 4KJDA 1E3CP 5TJ3A 4ZG9A 4GTXA 4NWJA 1ANIA 3M8ZA 1KHKA 1EW9A 4LQYA 5IJSA 4UOPA 1ALKA 4LRDA 1EJJA 1Y6VA 1P49A 3NVLA 4CXSA 3BDFA 4MY4A 5LRNA 1ALHA 2X98A 5KXAA 5L0EA 2W5TA 5EGEA 1FSUA 2GA3A 2GSUA 3T02A 3OT9A 1E33P 3WAWA 3UO0A 4KAVA 3WAVA
chains in the Genus database with same CATH superfamily
3E2DA 3Q3QA 4KAYA 5GOVA 2ANHA 3CMRA 5EGHA 3NKPA 4LRAA 1SHNA 3IDDA 5L0KA 1ALIA 1K7HA 3BDGA 3UN3A 2XR9A 1ELZA 4LRBA 3UN5A 1KH9A 3BDHA 1KH7A 5DLWA 3ED4A 3WAXA 5GRRA 3M8YA 3NKQA 1Y7AA 1O98A 2W8DA 1O99A 3KD8A 3NKRA 4GTYA 2W5XA 1AJCA 3IGYB 4TN0A 4UPLA 4UOOA 1HDHA 3TWZA 3M7VA 1ED8A 3NKOA 2QZUA 2GSOA 1KH5A 4GTZA 4LREA 5LRMA 1ED9A 1N2KA 3DPCA 1AJBA 3DYCA 3MK2A 4FDJA 3TX0A 4ZG7A 4ZGAA 5HRTA 1N2LA 1ANJA 1KH4A 1URAA 2GLQA 3UN2A 4CXKA 1ZEFA 4CYRA 5L0BA 3A52A 2D1GA 1KHLA 1KHJA 1ZEDA 3T00A 5K4PA 1E2SP 4QAXA 1KHNA 4NWXA 2IUCA 3MK0A 2W5SA 4LRCA 4UPIA 3NKMA 2RH6A 1ZEBA 4UPHA 1AUKA 3SZYA 4MHXA 4B56A 2IUCB 4YR1A 3NKNA 3B5QA 3T01A 5INHA 4CYSA 1URBA 4CXUA 2G9YA 4GTWA 2IFYA 1ELXA 5DLVA 1HQAA 4UPKA 1E1ZP 5C66A 3TG0A 1EQJA 4LR8A 1HJKA 3BDGB 2W5QA 1AJAA 2XRGA 5DLTA 2W5WA 4FDIA 2ZKTA 4KM4A 5LQQA 3WAYA 1EW8A 4LR7A 1AJDA 3M8WA 3UNYA 3SZZA 4N7TA 4MIVA 5LIAA 1EW2A 2W8SA 3IGZB 4LR9A 4KJGA 4LRFA 4UORA 3WBHA 2W5VA 5IJQA 2GSNA 1B8JA 2VQRA 1SHQA 3LXQA 1EI6A 3MK1A 4LR2A 1ELYA 5AJ9A 4ZG6A 2W5RA 1ALJA 4KJDA 1E3CP 5TJ3A 4ZG9A 4GTXA 4NWJA 1ANIA 3M8ZA 1KHKA 1EW9A 4LQYA 5IJSA 4UOPA 1ALKA 4LRDA 1EJJA 1Y6VA 1P49A 3NVLA 4CXSA 3BDFA 4MY4A 5LRNA 1ALHA 2X98A 5KXAA 5L0EA 2W5TA 5EGEA 1FSUA 2GA3A 2GSUA 3T02A 3OT9A 1E33P 3WAWA 3UO0A 4KAVA 3WAVA
chains in the Genus database with same CATH topology
3E2DA 3Q3QA 4KAYA 5GOVA 2ANHA 3CMRA 5EGHA 3NKPA 4LRAA 1SHNA 3IDDA 5L0KA 1ALIA 1K7HA 3BDGA 3UN3A 2XR9A 1ELZA 4LRBA 3UN5A 1KH9A 3BDHA 1KH7A 5DLWA 3ED4A 3WAXA 5GRRA 3M8YA 3NKQA 1Y7AA 1O98A 2W8DA 1O99A 3KD8A 3NKRA 4GTYA 2W5XA 1AJCA 3IGYB 4TN0A 4UPLA 4UOOA 1HDHA 3TWZA 3M7VA 1ED8A 3NKOA 2QZUA 2GSOA 1KH5A 4GTZA 4LREA 5LRMA 1ED9A 1N2KA 3DPCA 1AJBA 3DYCA 3MK2A 4FDJA 3TX0A 4ZG7A 4ZGAA 5HRTA 1N2LA 1ANJA 1KH4A 1URAA 2GLQA 3UN2A 4CXKA 1ZEFA 4CYRA 5L0BA 3A52A 2D1GA 1KHLA 1KHJA 1ZEDA 3T00A 5K4PA 1E2SP 4QAXA 1KHNA 4NWXA 2IUCA 3MK0A 2W5SA 4LRCA 4UPIA 3NKMA 2RH6A 1ZEBA 4UPHA 1AUKA 3SZYA 4MHXA 4B56A 2IUCB 4YR1A 3NKNA 3B5QA 3T01A 5INHA 4CYSA 1URBA 4CXUA 2G9YA 4GTWA 2IFYA 1ELXA 5DLVA 1HQAA 4UPKA 1E1ZP 5C66A 3TG0A 1EQJA 4LR8A 1HJKA 3BDGB 2W5QA 1AJAA 2XRGA 5DLTA 2W5WA 4FDIA 2ZKTA 4KM4A 5LQQA 3WAYA 1EW8A 4LR7A 1AJDA 3M8WA 3UNYA 3SZZA 4N7TA 4MIVA 5LIAA 1EW2A 2W8SA 3IGZB 4LR9A 4KJGA 4LRFA 4UORA 3WBHA 2W5VA 5IJQA 2GSNA 1B8JA 2VQRA 1SHQA 3LXQA 1EI6A 3MK1A 4LR2A 1ELYA 5AJ9A 4ZG6A 2W5RA 1ALJA 4KJDA 1E3CP 5TJ3A 4ZG9A 4GTXA 4NWJA 1ANIA 3M8ZA 1KHKA 1EW9A 4LQYA 5IJSA 4UOPA 1ALKA 4LRDA 1EJJA 1Y6VA 1P49A 3NVLA 4CXSA 3BDFA 4MY4A 5LRNA 1ALHA 2X98A 5KXAA 5L0EA 2W5TA 5EGEA 1FSUA 2GA3A 2GSUA 3T02A 3OT9A 1E33P 3WAWA 3UO0A 4KAVA 3WAVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E2D A;  3Q3Q A;  4KAY A;  5GOV A;  2ANH A;  3CMR A;  5EGH A;  3NKP A;  4LRA A;  1SHN A;  3IDD A;  5L0K A;  1ALI A;  1K7H A;  3BDG A;  3UN3 A;  2XR9 A;  1ELZ A;  4LRB A;  3UN5 A;  1KH9 A;  3BDH A;  1KH7 A;  5DLW A;  3ED4 A;  3WAX A;  5GRR A;  3M8Y A;  3NKQ A;  1Y7A A;  1O98 A;  2W8D A;  1O99 A;  3KD8 A;  3NKR A;  4GTY A;  2W5X A;  1AJC A;  3IGY B;  4TN0 A;  4UPL A;  4UOO A;  1HDH A;  3TWZ A;  3M7V A;  1ED8 A;  3NKO A;  2QZU A;  2GSO A;  1KH5 A;  4GTZ A;  4LRE A;  5LRM A;  1ED9 A;  1N2K A;  3DPC A;  1AJB A;  3DYC A;  3MK2 A;  4FDJ A;  3TX0 A;  4ZG7 A;  4ZGA A;  5HRT A;  1N2L A;  1ANJ A;  1KH4 A;  1URA A;  2GLQ A;  3UN2 A;  4CXK A;  1ZEF A;  4CYR A;  5L0B A;  3A52 A;  2D1G A;  1KHL A;  1KHJ A;  1ZED A;  3T00 A;  5K4P A;  1E2S P;  4QAX A;  1KHN A;  4NWX A;  2IUC A;  3MK0 A;  2W5S A;  4LRC A;  4UPI A;  3NKM A;  2RH6 A;  1ZEB A;  4UPH A;  1AUK A;  3SZY A;  4MHX A;  4B56 A;  2IUC B;  4YR1 A;  3NKN A;  3B5Q A;  3T01 A;  5INH A;  4CYS A;  1URB A;  4CXU A;  2G9Y A;  4GTW A;  2IFY A;  1ELX A;  5DLV A;  1HQA A;  4UPK A;  1E1Z P;  5C66 A;  3TG0 A;  1EQJ A;  4LR8 A;  1HJK A;  3BDG B;  2W5Q A;  1AJA A;  2XRG A;  5DLT A;  2W5W A;  4FDI A;  2ZKT A;  4KM4 A;  5LQQ A;  3WAY A;  1EW8 A;  4LR7 A;  1AJD A;  3M8W A;  3UNY A;  3SZZ A;  4N7T A;  4MIV A;  5LIA A;  1EW2 A;  2W8S A;  3IGZ B;  4LR9 A;  4KJG A;  4LRF A;  4UOR A;  3WBH A;  2W5V A;  5IJQ A;  2GSN A;  1B8J A;  2VQR A;  1SHQ A;  3LXQ A;  1EI6 A;  3MK1 A;  4LR2 A;  1ELY A;  5AJ9 A;  4ZG6 A;  2W5R A;  1ALJ A;  4KJD A;  1E3C P;  5TJ3 A;  4ZG9 A;  4GTX A;  4NWJ A;  1ANI A;  3M8Z A;  1KHK A;  1EW9 A;  4LQY A;  5IJS A;  4UOP A;  1ALK A;  4LRD A;  1EJJ A;  1Y6V A;  1P49 A;  3NVL A;  4CXS A;  3BDF A;  4MY4 A;  5LRN A;  1ALH A;  2X98 A;  5KXA A;  5L0E A;  2W5T A;  5EGE A;  1FSU A;  2GA3 A;  2GSU A;  3T02 A;  3OT9 A;  1E33 P;  3WAW A;  3UO0 A;  4KAV A;  3WAV A; 
#chains in the Genus database with same CATH topology
 3E2D A;  3Q3Q A;  4KAY A;  5GOV A;  2ANH A;  3CMR A;  5EGH A;  3NKP A;  4LRA A;  1SHN A;  3IDD A;  5L0K A;  1ALI A;  1K7H A;  3BDG A;  3UN3 A;  2XR9 A;  1ELZ A;  4LRB A;  3UN5 A;  1KH9 A;  3BDH A;  1KH7 A;  5DLW A;  3ED4 A;  3WAX A;  5GRR A;  3M8Y A;  3NKQ A;  1Y7A A;  1O98 A;  2W8D A;  1O99 A;  3KD8 A;  3NKR A;  4GTY A;  2W5X A;  1AJC A;  3IGY B;  4TN0 A;  4UPL A;  4UOO A;  1HDH A;  3TWZ A;  3M7V A;  1ED8 A;  3NKO A;  2QZU A;  2GSO A;  1KH5 A;  4GTZ A;  4LRE A;  5LRM A;  1ED9 A;  1N2K A;  3DPC A;  1AJB A;  3DYC A;  3MK2 A;  4FDJ A;  3TX0 A;  4ZG7 A;  4ZGA A;  5HRT A;  1N2L A;  1ANJ A;  1KH4 A;  1URA A;  2GLQ A;  3UN2 A;  4CXK A;  1ZEF A;  4CYR A;  5L0B A;  3A52 A;  2D1G A;  1KHL A;  1KHJ A;  1ZED A;  3T00 A;  5K4P A;  1E2S P;  4QAX A;  1KHN A;  4NWX A;  2IUC A;  3MK0 A;  2W5S A;  4LRC A;  4UPI A;  3NKM A;  2RH6 A;  1ZEB A;  4UPH A;  1AUK A;  3SZY A;  4MHX A;  4B56 A;  2IUC B;  4YR1 A;  3NKN A;  3B5Q A;  3T01 A;  5INH A;  4CYS A;  1URB A;  4CXU A;  2G9Y A;  4GTW A;  2IFY A;  1ELX A;  5DLV A;  1HQA A;  4UPK A;  1E1Z P;  5C66 A;  3TG0 A;  1EQJ A;  4LR8 A;  1HJK A;  3BDG B;  2W5Q A;  1AJA A;  2XRG A;  5DLT A;  2W5W A;  4FDI A;  2ZKT A;  4KM4 A;  5LQQ A;  3WAY A;  1EW8 A;  4LR7 A;  1AJD A;  3M8W A;  3UNY A;  3SZZ A;  4N7T A;  4MIV A;  5LIA A;  1EW2 A;  2W8S A;  3IGZ B;  4LR9 A;  4KJG A;  4LRF A;  4UOR A;  3WBH A;  2W5V A;  5IJQ A;  2GSN A;  1B8J A;  2VQR A;  1SHQ A;  3LXQ A;  1EI6 A;  3MK1 A;  4LR2 A;  1ELY A;  5AJ9 A;  4ZG6 A;  2W5R A;  1ALJ A;  4KJD A;  1E3C P;  5TJ3 A;  4ZG9 A;  4GTX A;  4NWJ A;  1ANI A;  3M8Z A;  1KHK A;  1EW9 A;  4LQY A;  5IJS A;  4UOP A;  1ALK A;  4LRD A;  1EJJ A;  1Y6V A;  1P49 A;  3NVL A;  4CXS A;  3BDF A;  4MY4 A;  5LRN A;  1ALH A;  2X98 A;  5KXA A;  5L0E A;  2W5T A;  5EGE A;  1FSU A;  2GA3 A;  2GSU A;  3T02 A;  3OT9 A;  1E33 P;  3WAW A;  3UO0 A;  4KAV A;  3WAV A; 
#chains in the Genus database with same CATH homology
 3E2D A;  3Q3Q A;  4KAY A;  5GOV A;  2ANH A;  3CMR A;  5EGH A;  3NKP A;  4LRA A;  1SHN A;  3IDD A;  5L0K A;  1ALI A;  1K7H A;  3BDG A;  3UN3 A;  2XR9 A;  1ELZ A;  4LRB A;  3UN5 A;  1KH9 A;  3BDH A;  1KH7 A;  5DLW A;  3ED4 A;  3WAX A;  5GRR A;  3M8Y A;  3NKQ A;  1Y7A A;  1O98 A;  2W8D A;  1O99 A;  3KD8 A;  3NKR A;  4GTY A;  2W5X A;  1AJC A;  3IGY B;  4TN0 A;  4UPL A;  4UOO A;  1HDH A;  3TWZ A;  3M7V A;  1ED8 A;  3NKO A;  2QZU A;  2GSO A;  1KH5 A;  4GTZ A;  4LRE A;  5LRM A;  1ED9 A;  1N2K A;  3DPC A;  1AJB A;  3DYC A;  3MK2 A;  4FDJ A;  3TX0 A;  4ZG7 A;  4ZGA A;  5HRT A;  1N2L A;  1ANJ A;  1KH4 A;  1URA A;  2GLQ A;  3UN2 A;  4CXK A;  1ZEF A;  4CYR A;  5L0B A;  3A52 A;  2D1G A;  1KHL A;  1KHJ A;  1ZED A;  3T00 A;  5K4P A;  1E2S P;  4QAX A;  1KHN A;  4NWX A;  2IUC A;  3MK0 A;  2W5S A;  4LRC A;  4UPI A;  3NKM A;  2RH6 A;  1ZEB A;  4UPH A;  1AUK A;  3SZY A;  4MHX A;  4B56 A;  2IUC B;  4YR1 A;  3NKN A;  3B5Q A;  3T01 A;  5INH A;  4CYS A;  1URB A;  4CXU A;  2G9Y A;  4GTW A;  2IFY A;  1ELX A;  5DLV A;  1HQA A;  4UPK A;  1E1Z P;  5C66 A;  3TG0 A;  1EQJ A;  4LR8 A;  1HJK A;  3BDG B;  2W5Q A;  1AJA A;  2XRG A;  5DLT A;  2W5W A;  4FDI A;  2ZKT A;  4KM4 A;  5LQQ A;  3WAY A;  1EW8 A;  4LR7 A;  1AJD A;  3M8W A;  3UNY A;  3SZZ A;  4N7T A;  4MIV A;  5LIA A;  1EW2 A;  2W8S A;  3IGZ B;  4LR9 A;  4KJG A;  4LRF A;  4UOR A;  3WBH A;  2W5V A;  5IJQ A;  2GSN A;  1B8J A;  2VQR A;  1SHQ A;  3LXQ A;  1EI6 A;  3MK1 A;  4LR2 A;  1ELY A;  5AJ9 A;  4ZG6 A;  2W5R A;  1ALJ A;  4KJD A;  1E3C P;  5TJ3 A;  4ZG9 A;  4GTX A;  4NWJ A;  1ANI A;  3M8Z A;  1KHK A;  1EW9 A;  4LQY A;  5IJS A;  4UOP A;  1ALK A;  4LRD A;  1EJJ A;  1Y6V A;  1P49 A;  3NVL A;  4CXS A;  3BDF A;  4MY4 A;  5LRN A;  1ALH A;  2X98 A;  5KXA A;  5L0E A;  2W5T A;  5EGE A;  1FSU A;  2GA3 A;  2GSU A;  3T02 A;  3OT9 A;  1E33 P;  3WAW A;  3UO0 A;  4KAV A;  3WAV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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