1O98A

1.4a crystal structure of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
Knots found
sequence length
509
structure length
509
Chain Sequence
SKKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE
publication title Insights Into the Catalytic Mechanism of Cofactor-Independent Phosphoglycerate Mutase from X-Ray Crystallography, Simulated Dynamics and Molecular Modeling
pubmed doi rcsb
source organism Bacillus stearothermophilus
total genus 199
structure length 509
sequence length 509
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2002-12-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1o98A02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1o98A01
1HQAA 4UOPA 4ZGAA 4LREA 1EW8A 1AJAA 2W8DA 2QZUA 4KJGA 1E2SP 3ED4A 2GSNA 4GTZA 4LRCA 3WAXA 3CMRA 1ZEDA 3NKQA 1E3CP 5LRNA 1N2KA 5IJQA 2XR9A 5K4PA 4LR8A 4LR7A 4LRAA 4LRBA 5EGEA 5DLWA 2IFYA 4QAXA 4N7TA 1KH9A 1KHNA 5TJ3A 3MK1A 3SZZA 1EQJA 3NVLA 3BDHA 4ZG9A 5L0EA 3BDGA 1ELXA 2D1GA 1ALHA 3WAYA 4B56A 3TG0A 3MK2A 3WBHA 2ANHA 1URAA 2IUCA 2RH6A 3BDFA 3NKRA 4FDJA 4MHXA 1E33P 2W5TA 1KHJA 3NKNA 2GLQA 5L0BA 4ZG7A 2W5RA 1SHNA 4CXSA 1ZEBA 3TWZA 3UN2A 3IDDA 5LRMA 3UN5A 1ANJA 3M8ZA 4UORA 1N2LA 3UO0A 4CYSA 5DLVA 3A52A 1KH4A 5INHA 2W5XA 2W5VA 1ZEFA 3T02A 5HRTA 3KD8A 1EJJA 3Q3QA 1ALIA 5GRRA 1EW2A 5LIAA 1Y6VA 4FDIA 3WAVA 4LRFA 2W5WA 4LRDA 5IJSA 4NWJA 1KH7A 1E1ZP 5LQQA 3IGZB 4UPHA 4NWXA 4UOOA 3M7VA 2GSOA 2G9YA 4TN0A 2X98A 4GTWA 4CYRA 3T00A 5AJ9A 1EW9A 3DPCA 5C66A 4UPKA 4UPIA 3T01A 1Y7AA 1HJKA 4KAVA 1ALKA 1P49A 3NKOA 4MIVA 4CXUA 2XRGA 3E2DA 3SZYA 4YR1A 1HDHA 3BDGB 4LR2A 1URBA 3MK0A 4KM4A 2W8SA 3UN3A 1AJBA 2W5SA 3IGYB 4LR9A 5GOVA 1AJDA 1K7HA 2IUCB 4UPLA 3NKPA 3NKMA 2GSUA 4GTYA 1ELZA 1ANIA 4CXKA 1O99A 1O98A 3M8WA 4MY4A 5KXAA 3DYCA 3OT9A 3LXQA 1KH5A 3UNYA 3M8YA 1AUKA 4GTXA 3TX0A 1ED8A 1ED9A 3WAWA 1KHLA 2VQRA 2ZKTA 4KJDA 1SHQA 1EI6A 4KAYA 1KHKA 2GA3A 4LQYA 5EGHA 5DLTA 4ZG6A 1AJCA 3B5QA 5L0KA 1ALJA 1B8JA 2W5QA 1FSUA 1ELYA
chains in the Genus database with same CATH superfamily
1HQAA 4UOPA 4ZGAA 4LREA 1EW8A 1AJAA 2W8DA 2QZUA 4KJGA 1E2SP 3ED4A 2GSNA 4GTZA 4LRCA 3WAXA 3CMRA 1ZEDA 3NKQA 1E3CP 5LRNA 1N2KA 5IJQA 2XR9A 5K4PA 4LR8A 4LR7A 4LRAA 4LRBA 5EGEA 5DLWA 2IFYA 4QAXA 4N7TA 1KH9A 1KHNA 5TJ3A 3MK1A 3SZZA 1EQJA 3NVLA 3BDHA 4ZG9A 5L0EA 3BDGA 1ELXA 2D1GA 1ALHA 3WAYA 4B56A 3TG0A 3MK2A 3WBHA 2ANHA 1URAA 2IUCA 2RH6A 3BDFA 3NKRA 4FDJA 4MHXA 1E33P 2W5TA 1KHJA 3NKNA 2GLQA 5L0BA 4ZG7A 2W5RA 1SHNA 4CXSA 1ZEBA 3TWZA 3UN2A 3IDDA 5LRMA 3UN5A 1ANJA 3M8ZA 4UORA 1N2LA 3UO0A 4CYSA 5DLVA 3A52A 1KH4A 5INHA 2W5XA 2W5VA 1ZEFA 3T02A 5HRTA 3KD8A 1EJJA 3Q3QA 1ALIA 5GRRA 1EW2A 5LIAA 1Y6VA 4FDIA 3WAVA 4LRFA 2W5WA 4LRDA 5IJSA 4NWJA 1KH7A 1E1ZP 5LQQA 3IGZB 4UPHA 4NWXA 4UOOA 3M7VA 2GSOA 2G9YA 4TN0A 2X98A 4GTWA 4CYRA 3T00A 5AJ9A 1EW9A 3DPCA 5C66A 4UPKA 4UPIA 3T01A 1Y7AA 1HJKA 4KAVA 1ALKA 1P49A 3NKOA 4MIVA 4CXUA 2XRGA 3E2DA 3SZYA 4YR1A 1HDHA 3BDGB 4LR2A 1URBA 3MK0A 4KM4A 2W8SA 3UN3A 1AJBA 2W5SA 3IGYB 4LR9A 5GOVA 1AJDA 1K7HA 2IUCB 4UPLA 3NKPA 3NKMA 2GSUA 4GTYA 1ELZA 1ANIA 4CXKA 1O99A 1O98A 3M8WA 4MY4A 5KXAA 3DYCA 3OT9A 3LXQA 1KH5A 3UNYA 3M8YA 1AUKA 4GTXA 3TX0A 1ED8A 1ED9A 3WAWA 1KHLA 2VQRA 2ZKTA 4KJDA 1SHQA 1EI6A 4KAYA 1KHKA 2GA3A 4LQYA 5EGHA 5DLTA 4ZG6A 1AJCA 3B5QA 5L0KA 1ALJA 1B8JA 2W5QA 1FSUA 1ELYA
chains in the Genus database with same CATH topology
1HQAA 4UOPA 4ZGAA 4LREA 1EW8A 1AJAA 2W8DA 2QZUA 4KJGA 1E2SP 3ED4A 2GSNA 4GTZA 4LRCA 3WAXA 3CMRA 1ZEDA 3NKQA 1E3CP 5LRNA 1N2KA 5IJQA 2XR9A 5K4PA 4LR8A 4LR7A 4LRAA 4LRBA 5EGEA 5DLWA 2IFYA 4QAXA 4N7TA 1KH9A 1KHNA 5TJ3A 3MK1A 3SZZA 1EQJA 3NVLA 3BDHA 4ZG9A 5L0EA 3BDGA 1ELXA 2D1GA 1ALHA 3WAYA 4B56A 3TG0A 3MK2A 3WBHA 2ANHA 1URAA 2IUCA 2RH6A 3BDFA 3NKRA 4FDJA 4MHXA 1E33P 2W5TA 1KHJA 3NKNA 2GLQA 5L0BA 4ZG7A 2W5RA 1SHNA 4CXSA 1ZEBA 3TWZA 3UN2A 3IDDA 5LRMA 3UN5A 1ANJA 3M8ZA 4UORA 1N2LA 3UO0A 4CYSA 5DLVA 3A52A 1KH4A 5INHA 2W5XA 2W5VA 1ZEFA 3T02A 5HRTA 3KD8A 1EJJA 3Q3QA 1ALIA 5GRRA 1EW2A 5LIAA 1Y6VA 4FDIA 3WAVA 4LRFA 2W5WA 4LRDA 5IJSA 4NWJA 1KH7A 1E1ZP 5LQQA 3IGZB 4UPHA 4NWXA 4UOOA 3M7VA 2GSOA 2G9YA 4TN0A 2X98A 4GTWA 4CYRA 3T00A 5AJ9A 1EW9A 3DPCA 5C66A 4UPKA 4UPIA 3T01A 1Y7AA 1HJKA 4KAVA 1ALKA 1P49A 3NKOA 4MIVA 4CXUA 2XRGA 3E2DA 3SZYA 4YR1A 1HDHA 3BDGB 4LR2A 1URBA 3MK0A 4KM4A 2W8SA 3UN3A 1AJBA 2W5SA 3IGYB 4LR9A 5GOVA 1AJDA 1K7HA 2IUCB 4UPLA 3NKPA 3NKMA 2GSUA 4GTYA 1ELZA 1ANIA 4CXKA 1O99A 1O98A 3M8WA 4MY4A 5KXAA 3DYCA 3OT9A 3LXQA 1KH5A 3UNYA 3M8YA 1AUKA 4GTXA 3TX0A 1ED8A 1ED9A 3WAWA 1KHLA 2VQRA 2ZKTA 4KJDA 1SHQA 1EI6A 4KAYA 1KHKA 2GA3A 4LQYA 5EGHA 5DLTA 4ZG6A 1AJCA 3B5QA 5L0KA 1ALJA 1B8JA 2W5QA 1FSUA 1ELYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HQA A;  4UOP A;  4ZGA A;  4LRE A;  1EW8 A;  1AJA A;  2W8D A;  2QZU A;  4KJG A;  1E2S P;  3ED4 A;  2GSN A;  4GTZ A;  4LRC A;  3WAX A;  3CMR A;  1ZED A;  3NKQ A;  1E3C P;  5LRN A;  1N2K A;  5IJQ A;  2XR9 A;  5K4P A;  4LR8 A;  4LR7 A;  4LRA A;  4LRB A;  5EGE A;  5DLW A;  2IFY A;  4QAX A;  4N7T A;  1KH9 A;  1KHN A;  5TJ3 A;  3MK1 A;  3SZZ A;  1EQJ A;  3NVL A;  3BDH A;  4ZG9 A;  5L0E A;  3BDG A;  1ELX A;  2D1G A;  1ALH A;  3WAY A;  4B56 A;  3TG0 A;  3MK2 A;  3WBH A;  2ANH A;  1URA A;  2IUC A;  2RH6 A;  3BDF A;  3NKR A;  4FDJ A;  4MHX A;  1E33 P;  2W5T A;  1KHJ A;  3NKN A;  2GLQ A;  5L0B A;  4ZG7 A;  2W5R A;  1SHN A;  4CXS A;  1ZEB A;  3TWZ A;  3UN2 A;  3IDD A;  5LRM A;  3UN5 A;  1ANJ A;  3M8Z A;  4UOR A;  1N2L A;  3UO0 A;  4CYS A;  5DLV A;  3A52 A;  1KH4 A;  5INH A;  2W5X A;  2W5V A;  1ZEF A;  3T02 A;  5HRT A;  3KD8 A;  1EJJ A;  3Q3Q A;  1ALI A;  5GRR A;  1EW2 A;  5LIA A;  1Y6V A;  4FDI A;  3WAV A;  4LRF A;  2W5W A;  4LRD A;  5IJS A;  4NWJ A;  1KH7 A;  1E1Z P;  5LQQ A;  3IGZ B;  4UPH A;  4NWX A;  4UOO A;  3M7V A;  2GSO A;  2G9Y A;  4TN0 A;  2X98 A;  4GTW A;  4CYR A;  3T00 A;  5AJ9 A;  1EW9 A;  3DPC A;  5C66 A;  4UPK A;  4UPI A;  3T01 A;  1Y7A A;  1HJK A;  4KAV A;  1ALK A;  1P49 A;  3NKO A;  4MIV A;  4CXU A;  2XRG A;  3E2D A;  3SZY A;  4YR1 A;  1HDH A;  3BDG B;  4LR2 A;  1URB A;  3MK0 A;  4KM4 A;  2W8S A;  3UN3 A;  1AJB A;  2W5S A;  3IGY B;  4LR9 A;  5GOV A;  1AJD A;  1K7H A;  2IUC B;  4UPL A;  3NKP A;  3NKM A;  2GSU A;  4GTY A;  1ELZ A;  1ANI A;  4CXK A;  1O99 A;  1O98 A;  3M8W A;  4MY4 A;  5KXA A;  3DYC A;  3OT9 A;  3LXQ A;  1KH5 A;  3UNY A;  3M8Y A;  1AUK A;  4GTX A;  3TX0 A;  1ED8 A;  1ED9 A;  3WAW A;  1KHL A;  2VQR A;  2ZKT A;  4KJD A;  1SHQ A;  1EI6 A;  4KAY A;  1KHK A;  2GA3 A;  4LQY A;  5EGH A;  5DLT A;  4ZG6 A;  1AJC A;  3B5Q A;  5L0K A;  1ALJ A;  1B8J A;  2W5Q A;  1FSU A;  1ELY A; 
#chains in the Genus database with same CATH topology
 1HQA A;  4UOP A;  4ZGA A;  4LRE A;  1EW8 A;  1AJA A;  2W8D A;  2QZU A;  4KJG A;  1E2S P;  3ED4 A;  2GSN A;  4GTZ A;  4LRC A;  3WAX A;  3CMR A;  1ZED A;  3NKQ A;  1E3C P;  5LRN A;  1N2K A;  5IJQ A;  2XR9 A;  5K4P A;  4LR8 A;  4LR7 A;  4LRA A;  4LRB A;  5EGE A;  5DLW A;  2IFY A;  4QAX A;  4N7T A;  1KH9 A;  1KHN A;  5TJ3 A;  3MK1 A;  3SZZ A;  1EQJ A;  3NVL A;  3BDH A;  4ZG9 A;  5L0E A;  3BDG A;  1ELX A;  2D1G A;  1ALH A;  3WAY A;  4B56 A;  3TG0 A;  3MK2 A;  3WBH A;  2ANH A;  1URA A;  2IUC A;  2RH6 A;  3BDF A;  3NKR A;  4FDJ A;  4MHX A;  1E33 P;  2W5T A;  1KHJ A;  3NKN A;  2GLQ A;  5L0B A;  4ZG7 A;  2W5R A;  1SHN A;  4CXS A;  1ZEB A;  3TWZ A;  3UN2 A;  3IDD A;  5LRM A;  3UN5 A;  1ANJ A;  3M8Z A;  4UOR A;  1N2L A;  3UO0 A;  4CYS A;  5DLV A;  3A52 A;  1KH4 A;  5INH A;  2W5X A;  2W5V A;  1ZEF A;  3T02 A;  5HRT A;  3KD8 A;  1EJJ A;  3Q3Q A;  1ALI A;  5GRR A;  1EW2 A;  5LIA A;  1Y6V A;  4FDI A;  3WAV A;  4LRF A;  2W5W A;  4LRD A;  5IJS A;  4NWJ A;  1KH7 A;  1E1Z P;  5LQQ A;  3IGZ B;  4UPH A;  4NWX A;  4UOO A;  3M7V A;  2GSO A;  2G9Y A;  4TN0 A;  2X98 A;  4GTW A;  4CYR A;  3T00 A;  5AJ9 A;  1EW9 A;  3DPC A;  5C66 A;  4UPK A;  4UPI A;  3T01 A;  1Y7A A;  1HJK A;  4KAV A;  1ALK A;  1P49 A;  3NKO A;  4MIV A;  4CXU A;  2XRG A;  3E2D A;  3SZY A;  4YR1 A;  1HDH A;  3BDG B;  4LR2 A;  1URB A;  3MK0 A;  4KM4 A;  2W8S A;  3UN3 A;  1AJB A;  2W5S A;  3IGY B;  4LR9 A;  5GOV A;  1AJD A;  1K7H A;  2IUC B;  4UPL A;  3NKP A;  3NKM A;  2GSU A;  4GTY A;  1ELZ A;  1ANI A;  4CXK A;  1O99 A;  1O98 A;  3M8W A;  4MY4 A;  5KXA A;  3DYC A;  3OT9 A;  3LXQ A;  1KH5 A;  3UNY A;  3M8Y A;  1AUK A;  4GTX A;  3TX0 A;  1ED8 A;  1ED9 A;  3WAW A;  1KHL A;  2VQR A;  2ZKT A;  4KJD A;  1SHQ A;  1EI6 A;  4KAY A;  1KHK A;  2GA3 A;  4LQY A;  5EGH A;  5DLT A;  4ZG6 A;  1AJC A;  3B5Q A;  5L0K A;  1ALJ A;  1B8J A;  2W5Q A;  1FSU A;  1ELY A; 
#chains in the Genus database with same CATH homology
 1HQA A;  4UOP A;  4ZGA A;  4LRE A;  1EW8 A;  1AJA A;  2W8D A;  2QZU A;  4KJG A;  1E2S P;  3ED4 A;  2GSN A;  4GTZ A;  4LRC A;  3WAX A;  3CMR A;  1ZED A;  3NKQ A;  1E3C P;  5LRN A;  1N2K A;  5IJQ A;  2XR9 A;  5K4P A;  4LR8 A;  4LR7 A;  4LRA A;  4LRB A;  5EGE A;  5DLW A;  2IFY A;  4QAX A;  4N7T A;  1KH9 A;  1KHN A;  5TJ3 A;  3MK1 A;  3SZZ A;  1EQJ A;  3NVL A;  3BDH A;  4ZG9 A;  5L0E A;  3BDG A;  1ELX A;  2D1G A;  1ALH A;  3WAY A;  4B56 A;  3TG0 A;  3MK2 A;  3WBH A;  2ANH A;  1URA A;  2IUC A;  2RH6 A;  3BDF A;  3NKR A;  4FDJ A;  4MHX A;  1E33 P;  2W5T A;  1KHJ A;  3NKN A;  2GLQ A;  5L0B A;  4ZG7 A;  2W5R A;  1SHN A;  4CXS A;  1ZEB A;  3TWZ A;  3UN2 A;  3IDD A;  5LRM A;  3UN5 A;  1ANJ A;  3M8Z A;  4UOR A;  1N2L A;  3UO0 A;  4CYS A;  5DLV A;  3A52 A;  1KH4 A;  5INH A;  2W5X A;  2W5V A;  1ZEF A;  3T02 A;  5HRT A;  3KD8 A;  1EJJ A;  3Q3Q A;  1ALI A;  5GRR A;  1EW2 A;  5LIA A;  1Y6V A;  4FDI A;  3WAV A;  4LRF A;  2W5W A;  4LRD A;  5IJS A;  4NWJ A;  1KH7 A;  1E1Z P;  5LQQ A;  3IGZ B;  4UPH A;  4NWX A;  4UOO A;  3M7V A;  2GSO A;  2G9Y A;  4TN0 A;  2X98 A;  4GTW A;  4CYR A;  3T00 A;  5AJ9 A;  1EW9 A;  3DPC A;  5C66 A;  4UPK A;  4UPI A;  3T01 A;  1Y7A A;  1HJK A;  4KAV A;  1ALK A;  1P49 A;  3NKO A;  4MIV A;  4CXU A;  2XRG A;  3E2D A;  3SZY A;  4YR1 A;  1HDH A;  3BDG B;  4LR2 A;  1URB A;  3MK0 A;  4KM4 A;  2W8S A;  3UN3 A;  1AJB A;  2W5S A;  3IGY B;  4LR9 A;  5GOV A;  1AJD A;  1K7H A;  2IUC B;  4UPL A;  3NKP A;  3NKM A;  2GSU A;  4GTY A;  1ELZ A;  1ANI A;  4CXK A;  1O99 A;  1O98 A;  3M8W A;  4MY4 A;  5KXA A;  3DYC A;  3OT9 A;  3LXQ A;  1KH5 A;  3UNY A;  3M8Y A;  1AUK A;  4GTX A;  3TX0 A;  1ED8 A;  1ED9 A;  3WAW A;  1KHL A;  2VQR A;  2ZKT A;  4KJD A;  1SHQ A;  1EI6 A;  4KAY A;  1KHK A;  2GA3 A;  4LQY A;  5EGH A;  5DLT A;  4ZG6 A;  1AJC A;  3B5Q A;  5L0K A;  1ALJ A;  1B8J A;  2W5Q A;  1FSU A;  1ELY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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