1EQJA

Crystal structure of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
Knots found
sequence length
508
structure length
508
Chain Sequence
KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords PHOSPHOGLYCERATE MUTASE
publication title Mechanism of catalysis of the cofactor-independent phosphoglycerate mutase from Bacillus stearothermophilus. Crystal structure of the complex with 2-phosphoglycerate.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
total genus 192
structure length 508
sequence length 508
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2000-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1eqjA02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1eqjA01
3Q3QA 1FSUA 2W5WA 3E2DA 4KAYA 1AJBA 3M8YA 1AJCA 5DLVA 3WAXA 1EQJA 4ZG6A 3IGYB 1KH9A 4UPHA 4CYRA 3MK0A 3T00A 5IJSA 3KD8A 1E3CP 1KHJA 1URAA 4MHXA 2IFYA 2IUCA 5LQQA 2W5VA 3WBHA 4LRDA 3ED4A 1N2LA 3UN5A 1ELZA 1P49A 4UOPA 5AJ9A 1E33P 3UN3A 4NWXA 1AUKA 5IJQA 4B56A 3NVLA 5GOVA 1EW2A 3MK2A 1EJJA 1ED9A 3A52A 1KHKA 1URBA 3IGZB 3M8WA 4CXKA 1ED8A 1EW9A 1ANIA 5HRTA 1ALIA 3DYCA 3IDDA 3LXQA 4LQYA 2ANHA 4CXUA 1EW8A 2W8SA 2XRGA 4MIVA 2G9YA 1ALJA 4N7TA 1KHLA 1ZEBA 2W5QA 3TWZA 5L0EA 2GA3A 4GTWA 1O98A 1KH5A 1ZEFA 1ELYA 5LIAA 2GSUA 3MK1A 3WAYA 2X98A 3UN2A 1KHNA 1O99A 2RH6A 1SHNA 1EI6A 1SHQA 1ANJA 4ZGAA 3CMRA 5INHA 2GSNA 5EGEA 1AJAA 2W5XA 3T01A 3SZZA 3WAVA 3NKOA 5DLWA 4KJDA 2W5SA 2XR9A 4KJGA 5LRNA 5LRMA 4LRBA 2GLQA 4TN0A 1E1ZP 1KH4A 2ZKTA 4FDIA 4NWJA 1ALHA 4GTYA 3OT9A 2W8DA 3NKRA 1HDHA 3TG0A 3BDFA 3WAWA 1HJKA 3UNYA 5EGHA 4ZG7A 5KXAA 1HQAA 5L0KA 3NKQA 3TX0A 4UPLA 4UPIA 4LRFA 3DPCA 3T02A 4LRCA 2W5TA 5DLTA 5TJ3A 3M8ZA 2W5RA 4UOOA 4ZG9A 1Y7AA 4MY4A 4UPKA 4CXSA 1B8JA 1AJDA 2D1GA 4LR9A 3BDGA 4GTZA 3BDGB 3UO0A 5K4PA 4GTXA 2IUCB 1N2KA 3B5QA 4YR1A 4LREA 4KAVA 1ZEDA 4QAXA 4LR2A 4LR7A 3SZYA 3NKPA 3M7VA 5GRRA 1E2SP 1K7HA 3BDHA 1ALKA 5C66A 4LR8A 2GSOA 4FDJA 4LRAA 1KH7A 4UORA 1Y6VA 4CYSA 3NKNA 4KM4A 3NKMA 2VQRA 2QZUA 5L0BA 1ELXA
chains in the Genus database with same CATH superfamily
3Q3QA 1FSUA 2W5WA 3E2DA 4KAYA 1AJBA 3M8YA 1AJCA 5DLVA 3WAXA 1EQJA 4ZG6A 3IGYB 1KH9A 4UPHA 4CYRA 3MK0A 3T00A 5IJSA 3KD8A 1E3CP 1KHJA 1URAA 4MHXA 2IFYA 2IUCA 5LQQA 2W5VA 3WBHA 4LRDA 3ED4A 1N2LA 3UN5A 1ELZA 1P49A 4UOPA 5AJ9A 1E33P 3UN3A 4NWXA 1AUKA 5IJQA 4B56A 3NVLA 5GOVA 1EW2A 3MK2A 1EJJA 1ED9A 3A52A 1KHKA 1URBA 3IGZB 3M8WA 4CXKA 1ED8A 1EW9A 1ANIA 5HRTA 1ALIA 3DYCA 3IDDA 3LXQA 4LQYA 2ANHA 4CXUA 1EW8A 2W8SA 2XRGA 4MIVA 2G9YA 1ALJA 4N7TA 1KHLA 1ZEBA 2W5QA 3TWZA 5L0EA 2GA3A 4GTWA 1O98A 1KH5A 1ZEFA 1ELYA 5LIAA 2GSUA 3MK1A 3WAYA 2X98A 3UN2A 1KHNA 1O99A 2RH6A 1SHNA 1EI6A 1SHQA 1ANJA 4ZGAA 3CMRA 5INHA 2GSNA 5EGEA 1AJAA 2W5XA 3T01A 3SZZA 3WAVA 3NKOA 5DLWA 4KJDA 2W5SA 2XR9A 4KJGA 5LRNA 5LRMA 4LRBA 2GLQA 4TN0A 1E1ZP 1KH4A 2ZKTA 4FDIA 4NWJA 1ALHA 4GTYA 3OT9A 2W8DA 3NKRA 1HDHA 3TG0A 3BDFA 3WAWA 1HJKA 3UNYA 5EGHA 4ZG7A 5KXAA 1HQAA 5L0KA 3NKQA 3TX0A 4UPLA 4UPIA 4LRFA 3DPCA 3T02A 4LRCA 2W5TA 5DLTA 5TJ3A 3M8ZA 2W5RA 4UOOA 4ZG9A 1Y7AA 4MY4A 4UPKA 4CXSA 1B8JA 1AJDA 2D1GA 4LR9A 3BDGA 4GTZA 3BDGB 3UO0A 5K4PA 4GTXA 2IUCB 1N2KA 3B5QA 4YR1A 4LREA 4KAVA 1ZEDA 4QAXA 4LR2A 4LR7A 3SZYA 3NKPA 3M7VA 5GRRA 1E2SP 1K7HA 3BDHA 1ALKA 5C66A 4LR8A 2GSOA 4FDJA 4LRAA 1KH7A 4UORA 1Y6VA 4CYSA 3NKNA 4KM4A 3NKMA 2VQRA 2QZUA 5L0BA 1ELXA
chains in the Genus database with same CATH topology
3Q3QA 1FSUA 2W5WA 3E2DA 4KAYA 1AJBA 3M8YA 1AJCA 5DLVA 3WAXA 1EQJA 4ZG6A 3IGYB 1KH9A 4UPHA 4CYRA 3MK0A 3T00A 5IJSA 3KD8A 1E3CP 1KHJA 1URAA 4MHXA 2IFYA 2IUCA 5LQQA 2W5VA 3WBHA 4LRDA 3ED4A 1N2LA 3UN5A 1ELZA 1P49A 4UOPA 5AJ9A 1E33P 3UN3A 4NWXA 1AUKA 5IJQA 4B56A 3NVLA 5GOVA 1EW2A 3MK2A 1EJJA 1ED9A 3A52A 1KHKA 1URBA 3IGZB 3M8WA 4CXKA 1ED8A 1EW9A 1ANIA 5HRTA 1ALIA 3DYCA 3IDDA 3LXQA 4LQYA 2ANHA 4CXUA 1EW8A 2W8SA 2XRGA 4MIVA 2G9YA 1ALJA 4N7TA 1KHLA 1ZEBA 2W5QA 3TWZA 5L0EA 2GA3A 4GTWA 1O98A 1KH5A 1ZEFA 1ELYA 5LIAA 2GSUA 3MK1A 3WAYA 2X98A 3UN2A 1KHNA 1O99A 2RH6A 1SHNA 1EI6A 1SHQA 1ANJA 4ZGAA 3CMRA 5INHA 2GSNA 5EGEA 1AJAA 2W5XA 3T01A 3SZZA 3WAVA 3NKOA 5DLWA 4KJDA 2W5SA 2XR9A 4KJGA 5LRNA 5LRMA 4LRBA 2GLQA 4TN0A 1E1ZP 1KH4A 2ZKTA 4FDIA 4NWJA 1ALHA 4GTYA 3OT9A 2W8DA 3NKRA 1HDHA 3TG0A 3BDFA 3WAWA 1HJKA 3UNYA 5EGHA 4ZG7A 5KXAA 1HQAA 5L0KA 3NKQA 3TX0A 4UPLA 4UPIA 4LRFA 3DPCA 3T02A 4LRCA 2W5TA 5DLTA 5TJ3A 3M8ZA 2W5RA 4UOOA 4ZG9A 1Y7AA 4MY4A 4UPKA 4CXSA 1B8JA 1AJDA 2D1GA 4LR9A 3BDGA 4GTZA 3BDGB 3UO0A 5K4PA 4GTXA 2IUCB 1N2KA 3B5QA 4YR1A 4LREA 4KAVA 1ZEDA 4QAXA 4LR2A 4LR7A 3SZYA 3NKPA 3M7VA 5GRRA 1E2SP 1K7HA 3BDHA 1ALKA 5C66A 4LR8A 2GSOA 4FDJA 4LRAA 1KH7A 4UORA 1Y6VA 4CYSA 3NKNA 4KM4A 3NKMA 2VQRA 2QZUA 5L0BA 1ELXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q3Q A;  1FSU A;  2W5W A;  3E2D A;  4KAY A;  1AJB A;  3M8Y A;  1AJC A;  5DLV A;  3WAX A;  1EQJ A;  4ZG6 A;  3IGY B;  1KH9 A;  4UPH A;  4CYR A;  3MK0 A;  3T00 A;  5IJS A;  3KD8 A;  1E3C P;  1KHJ A;  1URA A;  4MHX A;  2IFY A;  2IUC A;  5LQQ A;  2W5V A;  3WBH A;  4LRD A;  3ED4 A;  1N2L A;  3UN5 A;  1ELZ A;  1P49 A;  4UOP A;  5AJ9 A;  1E33 P;  3UN3 A;  4NWX A;  1AUK A;  5IJQ A;  4B56 A;  3NVL A;  5GOV A;  1EW2 A;  3MK2 A;  1EJJ A;  1ED9 A;  3A52 A;  1KHK A;  1URB A;  3IGZ B;  3M8W A;  4CXK A;  1ED8 A;  1EW9 A;  1ANI A;  5HRT A;  1ALI A;  3DYC A;  3IDD A;  3LXQ A;  4LQY A;  2ANH A;  4CXU A;  1EW8 A;  2W8S A;  2XRG A;  4MIV A;  2G9Y A;  1ALJ A;  4N7T A;  1KHL A;  1ZEB A;  2W5Q A;  3TWZ A;  5L0E A;  2GA3 A;  4GTW A;  1O98 A;  1KH5 A;  1ZEF A;  1ELY A;  5LIA A;  2GSU A;  3MK1 A;  3WAY A;  2X98 A;  3UN2 A;  1KHN A;  1O99 A;  2RH6 A;  1SHN A;  1EI6 A;  1SHQ A;  1ANJ A;  4ZGA A;  3CMR A;  5INH A;  2GSN A;  5EGE A;  1AJA A;  2W5X A;  3T01 A;  3SZZ A;  3WAV A;  3NKO A;  5DLW A;  4KJD A;  2W5S A;  2XR9 A;  4KJG A;  5LRN A;  5LRM A;  4LRB A;  2GLQ A;  4TN0 A;  1E1Z P;  1KH4 A;  2ZKT A;  4FDI A;  4NWJ A;  1ALH A;  4GTY A;  3OT9 A;  2W8D A;  3NKR A;  1HDH A;  3TG0 A;  3BDF A;  3WAW A;  1HJK A;  3UNY A;  5EGH A;  4ZG7 A;  5KXA A;  1HQA A;  5L0K A;  3NKQ A;  3TX0 A;  4UPL A;  4UPI A;  4LRF A;  3DPC A;  3T02 A;  4LRC A;  2W5T A;  5DLT A;  5TJ3 A;  3M8Z A;  2W5R A;  4UOO A;  4ZG9 A;  1Y7A A;  4MY4 A;  4UPK A;  4CXS A;  1B8J A;  1AJD A;  2D1G A;  4LR9 A;  3BDG A;  4GTZ A;  3BDG B;  3UO0 A;  5K4P A;  4GTX A;  2IUC B;  1N2K A;  3B5Q A;  4YR1 A;  4LRE A;  4KAV A;  1ZED A;  4QAX A;  4LR2 A;  4LR7 A;  3SZY A;  3NKP A;  3M7V A;  5GRR A;  1E2S P;  1K7H A;  3BDH A;  1ALK A;  5C66 A;  4LR8 A;  2GSO A;  4FDJ A;  4LRA A;  1KH7 A;  4UOR A;  1Y6V A;  4CYS A;  3NKN A;  4KM4 A;  3NKM A;  2VQR A;  2QZU A;  5L0B A;  1ELX A; 
#chains in the Genus database with same CATH topology
 3Q3Q A;  1FSU A;  2W5W A;  3E2D A;  4KAY A;  1AJB A;  3M8Y A;  1AJC A;  5DLV A;  3WAX A;  1EQJ A;  4ZG6 A;  3IGY B;  1KH9 A;  4UPH A;  4CYR A;  3MK0 A;  3T00 A;  5IJS A;  3KD8 A;  1E3C P;  1KHJ A;  1URA A;  4MHX A;  2IFY A;  2IUC A;  5LQQ A;  2W5V A;  3WBH A;  4LRD A;  3ED4 A;  1N2L A;  3UN5 A;  1ELZ A;  1P49 A;  4UOP A;  5AJ9 A;  1E33 P;  3UN3 A;  4NWX A;  1AUK A;  5IJQ A;  4B56 A;  3NVL A;  5GOV A;  1EW2 A;  3MK2 A;  1EJJ A;  1ED9 A;  3A52 A;  1KHK A;  1URB A;  3IGZ B;  3M8W A;  4CXK A;  1ED8 A;  1EW9 A;  1ANI A;  5HRT A;  1ALI A;  3DYC A;  3IDD A;  3LXQ A;  4LQY A;  2ANH A;  4CXU A;  1EW8 A;  2W8S A;  2XRG A;  4MIV A;  2G9Y A;  1ALJ A;  4N7T A;  1KHL A;  1ZEB A;  2W5Q A;  3TWZ A;  5L0E A;  2GA3 A;  4GTW A;  1O98 A;  1KH5 A;  1ZEF A;  1ELY A;  5LIA A;  2GSU A;  3MK1 A;  3WAY A;  2X98 A;  3UN2 A;  1KHN A;  1O99 A;  2RH6 A;  1SHN A;  1EI6 A;  1SHQ A;  1ANJ A;  4ZGA A;  3CMR A;  5INH A;  2GSN A;  5EGE A;  1AJA A;  2W5X A;  3T01 A;  3SZZ A;  3WAV A;  3NKO A;  5DLW A;  4KJD A;  2W5S A;  2XR9 A;  4KJG A;  5LRN A;  5LRM A;  4LRB A;  2GLQ A;  4TN0 A;  1E1Z P;  1KH4 A;  2ZKT A;  4FDI A;  4NWJ A;  1ALH A;  4GTY A;  3OT9 A;  2W8D A;  3NKR A;  1HDH A;  3TG0 A;  3BDF A;  3WAW A;  1HJK A;  3UNY A;  5EGH A;  4ZG7 A;  5KXA A;  1HQA A;  5L0K A;  3NKQ A;  3TX0 A;  4UPL A;  4UPI A;  4LRF A;  3DPC A;  3T02 A;  4LRC A;  2W5T A;  5DLT A;  5TJ3 A;  3M8Z A;  2W5R A;  4UOO A;  4ZG9 A;  1Y7A A;  4MY4 A;  4UPK A;  4CXS A;  1B8J A;  1AJD A;  2D1G A;  4LR9 A;  3BDG A;  4GTZ A;  3BDG B;  3UO0 A;  5K4P A;  4GTX A;  2IUC B;  1N2K A;  3B5Q A;  4YR1 A;  4LRE A;  4KAV A;  1ZED A;  4QAX A;  4LR2 A;  4LR7 A;  3SZY A;  3NKP A;  3M7V A;  5GRR A;  1E2S P;  1K7H A;  3BDH A;  1ALK A;  5C66 A;  4LR8 A;  2GSO A;  4FDJ A;  4LRA A;  1KH7 A;  4UOR A;  1Y6V A;  4CYS A;  3NKN A;  4KM4 A;  3NKM A;  2VQR A;  2QZU A;  5L0B A;  1ELX A; 
#chains in the Genus database with same CATH homology
 3Q3Q A;  1FSU A;  2W5W A;  3E2D A;  4KAY A;  1AJB A;  3M8Y A;  1AJC A;  5DLV A;  3WAX A;  1EQJ A;  4ZG6 A;  3IGY B;  1KH9 A;  4UPH A;  4CYR A;  3MK0 A;  3T00 A;  5IJS A;  3KD8 A;  1E3C P;  1KHJ A;  1URA A;  4MHX A;  2IFY A;  2IUC A;  5LQQ A;  2W5V A;  3WBH A;  4LRD A;  3ED4 A;  1N2L A;  3UN5 A;  1ELZ A;  1P49 A;  4UOP A;  5AJ9 A;  1E33 P;  3UN3 A;  4NWX A;  1AUK A;  5IJQ A;  4B56 A;  3NVL A;  5GOV A;  1EW2 A;  3MK2 A;  1EJJ A;  1ED9 A;  3A52 A;  1KHK A;  1URB A;  3IGZ B;  3M8W A;  4CXK A;  1ED8 A;  1EW9 A;  1ANI A;  5HRT A;  1ALI A;  3DYC A;  3IDD A;  3LXQ A;  4LQY A;  2ANH A;  4CXU A;  1EW8 A;  2W8S A;  2XRG A;  4MIV A;  2G9Y A;  1ALJ A;  4N7T A;  1KHL A;  1ZEB A;  2W5Q A;  3TWZ A;  5L0E A;  2GA3 A;  4GTW A;  1O98 A;  1KH5 A;  1ZEF A;  1ELY A;  5LIA A;  2GSU A;  3MK1 A;  3WAY A;  2X98 A;  3UN2 A;  1KHN A;  1O99 A;  2RH6 A;  1SHN A;  1EI6 A;  1SHQ A;  1ANJ A;  4ZGA A;  3CMR A;  5INH A;  2GSN A;  5EGE A;  1AJA A;  2W5X A;  3T01 A;  3SZZ A;  3WAV A;  3NKO A;  5DLW A;  4KJD A;  2W5S A;  2XR9 A;  4KJG A;  5LRN A;  5LRM A;  4LRB A;  2GLQ A;  4TN0 A;  1E1Z P;  1KH4 A;  2ZKT A;  4FDI A;  4NWJ A;  1ALH A;  4GTY A;  3OT9 A;  2W8D A;  3NKR A;  1HDH A;  3TG0 A;  3BDF A;  3WAW A;  1HJK A;  3UNY A;  5EGH A;  4ZG7 A;  5KXA A;  1HQA A;  5L0K A;  3NKQ A;  3TX0 A;  4UPL A;  4UPI A;  4LRF A;  3DPC A;  3T02 A;  4LRC A;  2W5T A;  5DLT A;  5TJ3 A;  3M8Z A;  2W5R A;  4UOO A;  4ZG9 A;  1Y7A A;  4MY4 A;  4UPK A;  4CXS A;  1B8J A;  1AJD A;  2D1G A;  4LR9 A;  3BDG A;  4GTZ A;  3BDG B;  3UO0 A;  5K4P A;  4GTX A;  2IUC B;  1N2K A;  3B5Q A;  4YR1 A;  4LRE A;  4KAV A;  1ZED A;  4QAX A;  4LR2 A;  4LR7 A;  3SZY A;  3NKP A;  3M7V A;  5GRR A;  1E2S P;  1K7H A;  3BDH A;  1ALK A;  5C66 A;  4LR8 A;  2GSO A;  4FDJ A;  4LRA A;  1KH7 A;  4UOR A;  1Y6V A;  4CYS A;  3NKN A;  4KM4 A;  3NKM A;  2VQR A;  2QZU A;  5L0B A;  1ELX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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