1EQJA

Crystal structure of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
Knots found
sequence length
508
structure length
508
Chain Sequence
KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanism of catalysis of the cofactor-independent phosphoglycerate mutase from Bacillus stearothermophilus. Crystal structure of the complex with 2-phosphoglycerate.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
molecule tags Isomerase
molecule keywords PHOSPHOGLYCERATE MUTASE
total genus 192
structure length 508
sequence length 508
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2000-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1eqjA02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1eqjA01
2GSNA 1KH4A 1ZEFA 1AUKA 4UOPA 1KHKA 2GA3A 5EGEA 3WAVA 1ALJA 2W8SA 4UOOA 3M8YA 3WAYA 1ANJA 3T00A 2IUCA 5LQQA 4MHXA 1ED8A 4KAYA 3NVLA 4LR9A 4FDIA 4UORA 5EGHA 2W5VA 5DLWA 4LRBA 4NWJA 2W5SA 3NKQA 3A52A 4CYSA 3IDDA 4N7TA 1SHQA 1EQJA 2XRGA 3MK1A 3UN5A 1HQAA 2W5XA 5AJ9A 1KH5A 2GSUA 3IGZB 4YR1A 1ELZA 1HDHA 4KAVA 5GOVA 1URBA 2W5RA 3UO0A 4GTXA 4NWXA 1K7HA 1KH9A 1EW2A 4LR2A 1P49A 5GRRA 3M7VA 5DLTA 3BDGB 1AJDA 1EJJA 4LRAA 2IUCB 3MK2A 1EI6A 1ALIA 3WBHA 5IJSA 2D1GA 3M8ZA 4ZG7A 1E2SP 4CXSA 1KHNA 1KH7A 2GLQA 3KD8A 3UNYA 5INHA 5IJQA 1EW9A 2XR9A 1ZEDA 1FSUA 2RH6A 2X98A 3IGYB 5K4PA 4ZG9A 2W5WA 3SZZA 1HJKA 2W5QA 4MY4A 1SHNA 1ALHA 3LXQA 1Y7AA 1ALKA 1O98A 3E2DA 3OT9A 1EW8A 3BDHA 1N2LA 4LQYA 1B8JA 3DYCA 2G9YA 3MK0A 3NKOA 5LRNA 4UPKA 2VQRA 3WAXA 3NKPA 1ZEBA 4UPIA 1ELXA 4B56A 4UPHA 1AJBA 3TX0A 3NKRA 3Q3QA 1E3CP 1E1ZP 4GTWA 3NKNA 5L0EA 2IFYA 5L0BA 4KM4A 1URAA 2GSOA 4LREA 1O99A 4GTZA 4MIVA 3WAWA 4TN0A 4ZG6A 5HRTA 5LIAA 4LRFA 1ANIA 3BDFA 2ANHA 3M8WA 4CYRA 4CXKA 1E33P 1AJAA 3ED4A 3T02A 2ZKTA 4ZGAA 5C66A 4LR8A 4KJDA 3DPCA 4FDJA 4QAXA 5KXAA 5TJ3A 1Y6VA 4LR7A 3BDGA 3UN3A 1KHLA 3B5QA 3SZYA 1ELYA 5LRMA 1ED9A 1N2KA 2W8DA 3TG0A 3UN2A 4KJGA 4CXUA 2W5TA 3CMRA 1KHJA 4UPLA 1AJCA 4LRCA 5DLVA 2QZUA 4LRDA 5L0KA 4GTYA 3TWZA 3T01A 3NKMA
chains in the Genus database with same CATH superfamily
2GSNA 1KH4A 1ZEFA 1AUKA 4UOPA 1KHKA 2GA3A 5EGEA 3WAVA 1ALJA 2W8SA 4UOOA 3M8YA 3WAYA 1ANJA 3T00A 2IUCA 5LQQA 4MHXA 1ED8A 4KAYA 3NVLA 4LR9A 4FDIA 4UORA 5EGHA 2W5VA 5DLWA 4LRBA 4NWJA 2W5SA 3NKQA 3A52A 4CYSA 3IDDA 4N7TA 1SHQA 1EQJA 2XRGA 3MK1A 3UN5A 1HQAA 2W5XA 5AJ9A 1KH5A 2GSUA 3IGZB 4YR1A 1ELZA 1HDHA 4KAVA 5GOVA 1URBA 2W5RA 3UO0A 4GTXA 4NWXA 1K7HA 1KH9A 1EW2A 4LR2A 1P49A 5GRRA 3M7VA 5DLTA 3BDGB 1AJDA 1EJJA 4LRAA 2IUCB 3MK2A 1EI6A 1ALIA 3WBHA 5IJSA 2D1GA 3M8ZA 4ZG7A 1E2SP 4CXSA 1KHNA 1KH7A 2GLQA 3KD8A 3UNYA 5INHA 5IJQA 1EW9A 2XR9A 1ZEDA 1FSUA 2RH6A 2X98A 3IGYB 5K4PA 4ZG9A 2W5WA 3SZZA 1HJKA 2W5QA 4MY4A 1SHNA 1ALHA 3LXQA 1Y7AA 1ALKA 1O98A 3E2DA 3OT9A 1EW8A 3BDHA 1N2LA 4LQYA 1B8JA 3DYCA 2G9YA 3MK0A 3NKOA 5LRNA 4UPKA 2VQRA 3WAXA 3NKPA 1ZEBA 4UPIA 1ELXA 4B56A 4UPHA 1AJBA 3TX0A 3NKRA 3Q3QA 1E3CP 1E1ZP 4GTWA 3NKNA 5L0EA 2IFYA 5L0BA 4KM4A 1URAA 2GSOA 4LREA 1O99A 4GTZA 4MIVA 3WAWA 4TN0A 4ZG6A 5HRTA 5LIAA 4LRFA 1ANIA 3BDFA 2ANHA 3M8WA 4CYRA 4CXKA 1E33P 1AJAA 3ED4A 3T02A 2ZKTA 4ZGAA 5C66A 4LR8A 4KJDA 3DPCA 4FDJA 4QAXA 5KXAA 5TJ3A 1Y6VA 4LR7A 3BDGA 3UN3A 1KHLA 3B5QA 3SZYA 1ELYA 5LRMA 1ED9A 1N2KA 2W8DA 3TG0A 3UN2A 4KJGA 4CXUA 2W5TA 3CMRA 1KHJA 4UPLA 1AJCA 4LRCA 5DLVA 2QZUA 4LRDA 5L0KA 4GTYA 3TWZA 3T01A 3NKMA
chains in the Genus database with same CATH topology
2GSNA 1KH4A 1ZEFA 1AUKA 4UOPA 1KHKA 2GA3A 5EGEA 3WAVA 1ALJA 2W8SA 4UOOA 3M8YA 3WAYA 1ANJA 3T00A 2IUCA 5LQQA 4MHXA 1ED8A 4KAYA 3NVLA 4LR9A 4FDIA 4UORA 5EGHA 2W5VA 5DLWA 4LRBA 4NWJA 2W5SA 3NKQA 3A52A 4CYSA 3IDDA 4N7TA 1SHQA 1EQJA 2XRGA 3MK1A 3UN5A 1HQAA 2W5XA 5AJ9A 1KH5A 2GSUA 3IGZB 4YR1A 1ELZA 1HDHA 4KAVA 5GOVA 1URBA 2W5RA 3UO0A 4GTXA 4NWXA 1K7HA 1KH9A 1EW2A 4LR2A 1P49A 5GRRA 3M7VA 5DLTA 3BDGB 1AJDA 1EJJA 4LRAA 2IUCB 3MK2A 1EI6A 1ALIA 3WBHA 5IJSA 2D1GA 3M8ZA 4ZG7A 1E2SP 4CXSA 1KHNA 1KH7A 2GLQA 3KD8A 3UNYA 5INHA 5IJQA 1EW9A 2XR9A 1ZEDA 1FSUA 2RH6A 2X98A 3IGYB 5K4PA 4ZG9A 2W5WA 3SZZA 1HJKA 2W5QA 4MY4A 1SHNA 1ALHA 3LXQA 1Y7AA 1ALKA 1O98A 3E2DA 3OT9A 1EW8A 3BDHA 1N2LA 4LQYA 1B8JA 3DYCA 2G9YA 3MK0A 3NKOA 5LRNA 4UPKA 2VQRA 3WAXA 3NKPA 1ZEBA 4UPIA 1ELXA 4B56A 4UPHA 1AJBA 3TX0A 3NKRA 3Q3QA 1E3CP 1E1ZP 4GTWA 3NKNA 5L0EA 2IFYA 5L0BA 4KM4A 1URAA 2GSOA 4LREA 1O99A 4GTZA 4MIVA 3WAWA 4TN0A 4ZG6A 5HRTA 5LIAA 4LRFA 1ANIA 3BDFA 2ANHA 3M8WA 4CYRA 4CXKA 1E33P 1AJAA 3ED4A 3T02A 2ZKTA 4ZGAA 5C66A 4LR8A 4KJDA 3DPCA 4FDJA 4QAXA 5KXAA 5TJ3A 1Y6VA 4LR7A 3BDGA 3UN3A 1KHLA 3B5QA 3SZYA 1ELYA 5LRMA 1ED9A 1N2KA 2W8DA 3TG0A 3UN2A 4KJGA 4CXUA 2W5TA 3CMRA 1KHJA 4UPLA 1AJCA 4LRCA 5DLVA 2QZUA 4LRDA 5L0KA 4GTYA 3TWZA 3T01A 3NKMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GSN A;  1KH4 A;  1ZEF A;  1AUK A;  4UOP A;  1KHK A;  2GA3 A;  5EGE A;  3WAV A;  1ALJ A;  2W8S A;  4UOO A;  3M8Y A;  3WAY A;  1ANJ A;  3T00 A;  2IUC A;  5LQQ A;  4MHX A;  1ED8 A;  4KAY A;  3NVL A;  4LR9 A;  4FDI A;  4UOR A;  5EGH A;  2W5V A;  5DLW A;  4LRB A;  4NWJ A;  2W5S A;  3NKQ A;  3A52 A;  4CYS A;  3IDD A;  4N7T A;  1SHQ A;  1EQJ A;  2XRG A;  3MK1 A;  3UN5 A;  1HQA A;  2W5X A;  5AJ9 A;  1KH5 A;  2GSU A;  3IGZ B;  4YR1 A;  1ELZ A;  1HDH A;  4KAV A;  5GOV A;  1URB A;  2W5R A;  3UO0 A;  4GTX A;  4NWX A;  1K7H A;  1KH9 A;  1EW2 A;  4LR2 A;  1P49 A;  5GRR A;  3M7V A;  5DLT A;  3BDG B;  1AJD A;  1EJJ A;  4LRA A;  2IUC B;  3MK2 A;  1EI6 A;  1ALI A;  3WBH A;  5IJS A;  2D1G A;  3M8Z A;  4ZG7 A;  1E2S P;  4CXS A;  1KHN A;  1KH7 A;  2GLQ A;  3KD8 A;  3UNY A;  5INH A;  5IJQ A;  1EW9 A;  2XR9 A;  1ZED A;  1FSU A;  2RH6 A;  2X98 A;  3IGY B;  5K4P A;  4ZG9 A;  2W5W A;  3SZZ A;  1HJK A;  2W5Q A;  4MY4 A;  1SHN A;  1ALH A;  3LXQ A;  1Y7A A;  1ALK A;  1O98 A;  3E2D A;  3OT9 A;  1EW8 A;  3BDH A;  1N2L A;  4LQY A;  1B8J A;  3DYC A;  2G9Y A;  3MK0 A;  3NKO A;  5LRN A;  4UPK A;  2VQR A;  3WAX A;  3NKP A;  1ZEB A;  4UPI A;  1ELX A;  4B56 A;  4UPH A;  1AJB A;  3TX0 A;  3NKR A;  3Q3Q A;  1E3C P;  1E1Z P;  4GTW A;  3NKN A;  5L0E A;  2IFY A;  5L0B A;  4KM4 A;  1URA A;  2GSO A;  4LRE A;  1O99 A;  4GTZ A;  4MIV A;  3WAW A;  4TN0 A;  4ZG6 A;  5HRT A;  5LIA A;  4LRF A;  1ANI A;  3BDF A;  2ANH A;  3M8W A;  4CYR A;  4CXK A;  1E33 P;  1AJA A;  3ED4 A;  3T02 A;  2ZKT A;  4ZGA A;  5C66 A;  4LR8 A;  4KJD A;  3DPC A;  4FDJ A;  4QAX A;  5KXA A;  5TJ3 A;  1Y6V A;  4LR7 A;  3BDG A;  3UN3 A;  1KHL A;  3B5Q A;  3SZY A;  1ELY A;  5LRM A;  1ED9 A;  1N2K A;  2W8D A;  3TG0 A;  3UN2 A;  4KJG A;  4CXU A;  2W5T A;  3CMR A;  1KHJ A;  4UPL A;  1AJC A;  4LRC A;  5DLV A;  2QZU A;  4LRD A;  5L0K A;  4GTY A;  3TWZ A;  3T01 A;  3NKM A; 
#chains in the Genus database with same CATH topology
 2GSN A;  1KH4 A;  1ZEF A;  1AUK A;  4UOP A;  1KHK A;  2GA3 A;  5EGE A;  3WAV A;  1ALJ A;  2W8S A;  4UOO A;  3M8Y A;  3WAY A;  1ANJ A;  3T00 A;  2IUC A;  5LQQ A;  4MHX A;  1ED8 A;  4KAY A;  3NVL A;  4LR9 A;  4FDI A;  4UOR A;  5EGH A;  2W5V A;  5DLW A;  4LRB A;  4NWJ A;  2W5S A;  3NKQ A;  3A52 A;  4CYS A;  3IDD A;  4N7T A;  1SHQ A;  1EQJ A;  2XRG A;  3MK1 A;  3UN5 A;  1HQA A;  2W5X A;  5AJ9 A;  1KH5 A;  2GSU A;  3IGZ B;  4YR1 A;  1ELZ A;  1HDH A;  4KAV A;  5GOV A;  1URB A;  2W5R A;  3UO0 A;  4GTX A;  4NWX A;  1K7H A;  1KH9 A;  1EW2 A;  4LR2 A;  1P49 A;  5GRR A;  3M7V A;  5DLT A;  3BDG B;  1AJD A;  1EJJ A;  4LRA A;  2IUC B;  3MK2 A;  1EI6 A;  1ALI A;  3WBH A;  5IJS A;  2D1G A;  3M8Z A;  4ZG7 A;  1E2S P;  4CXS A;  1KHN A;  1KH7 A;  2GLQ A;  3KD8 A;  3UNY A;  5INH A;  5IJQ A;  1EW9 A;  2XR9 A;  1ZED A;  1FSU A;  2RH6 A;  2X98 A;  3IGY B;  5K4P A;  4ZG9 A;  2W5W A;  3SZZ A;  1HJK A;  2W5Q A;  4MY4 A;  1SHN A;  1ALH A;  3LXQ A;  1Y7A A;  1ALK A;  1O98 A;  3E2D A;  3OT9 A;  1EW8 A;  3BDH A;  1N2L A;  4LQY A;  1B8J A;  3DYC A;  2G9Y A;  3MK0 A;  3NKO A;  5LRN A;  4UPK A;  2VQR A;  3WAX A;  3NKP A;  1ZEB A;  4UPI A;  1ELX A;  4B56 A;  4UPH A;  1AJB A;  3TX0 A;  3NKR A;  3Q3Q A;  1E3C P;  1E1Z P;  4GTW A;  3NKN A;  5L0E A;  2IFY A;  5L0B A;  4KM4 A;  1URA A;  2GSO A;  4LRE A;  1O99 A;  4GTZ A;  4MIV A;  3WAW A;  4TN0 A;  4ZG6 A;  5HRT A;  5LIA A;  4LRF A;  1ANI A;  3BDF A;  2ANH A;  3M8W A;  4CYR A;  4CXK A;  1E33 P;  1AJA A;  3ED4 A;  3T02 A;  2ZKT A;  4ZGA A;  5C66 A;  4LR8 A;  4KJD A;  3DPC A;  4FDJ A;  4QAX A;  5KXA A;  5TJ3 A;  1Y6V A;  4LR7 A;  3BDG A;  3UN3 A;  1KHL A;  3B5Q A;  3SZY A;  1ELY A;  5LRM A;  1ED9 A;  1N2K A;  2W8D A;  3TG0 A;  3UN2 A;  4KJG A;  4CXU A;  2W5T A;  3CMR A;  1KHJ A;  4UPL A;  1AJC A;  4LRC A;  5DLV A;  2QZU A;  4LRD A;  5L0K A;  4GTY A;  3TWZ A;  3T01 A;  3NKM A; 
#chains in the Genus database with same CATH homology
 2GSN A;  1KH4 A;  1ZEF A;  1AUK A;  4UOP A;  1KHK A;  2GA3 A;  5EGE A;  3WAV A;  1ALJ A;  2W8S A;  4UOO A;  3M8Y A;  3WAY A;  1ANJ A;  3T00 A;  2IUC A;  5LQQ A;  4MHX A;  1ED8 A;  4KAY A;  3NVL A;  4LR9 A;  4FDI A;  4UOR A;  5EGH A;  2W5V A;  5DLW A;  4LRB A;  4NWJ A;  2W5S A;  3NKQ A;  3A52 A;  4CYS A;  3IDD A;  4N7T A;  1SHQ A;  1EQJ A;  2XRG A;  3MK1 A;  3UN5 A;  1HQA A;  2W5X A;  5AJ9 A;  1KH5 A;  2GSU A;  3IGZ B;  4YR1 A;  1ELZ A;  1HDH A;  4KAV A;  5GOV A;  1URB A;  2W5R A;  3UO0 A;  4GTX A;  4NWX A;  1K7H A;  1KH9 A;  1EW2 A;  4LR2 A;  1P49 A;  5GRR A;  3M7V A;  5DLT A;  3BDG B;  1AJD A;  1EJJ A;  4LRA A;  2IUC B;  3MK2 A;  1EI6 A;  1ALI A;  3WBH A;  5IJS A;  2D1G A;  3M8Z A;  4ZG7 A;  1E2S P;  4CXS A;  1KHN A;  1KH7 A;  2GLQ A;  3KD8 A;  3UNY A;  5INH A;  5IJQ A;  1EW9 A;  2XR9 A;  1ZED A;  1FSU A;  2RH6 A;  2X98 A;  3IGY B;  5K4P A;  4ZG9 A;  2W5W A;  3SZZ A;  1HJK A;  2W5Q A;  4MY4 A;  1SHN A;  1ALH A;  3LXQ A;  1Y7A A;  1ALK A;  1O98 A;  3E2D A;  3OT9 A;  1EW8 A;  3BDH A;  1N2L A;  4LQY A;  1B8J A;  3DYC A;  2G9Y A;  3MK0 A;  3NKO A;  5LRN A;  4UPK A;  2VQR A;  3WAX A;  3NKP A;  1ZEB A;  4UPI A;  1ELX A;  4B56 A;  4UPH A;  1AJB A;  3TX0 A;  3NKR A;  3Q3Q A;  1E3C P;  1E1Z P;  4GTW A;  3NKN A;  5L0E A;  2IFY A;  5L0B A;  4KM4 A;  1URA A;  2GSO A;  4LRE A;  1O99 A;  4GTZ A;  4MIV A;  3WAW A;  4TN0 A;  4ZG6 A;  5HRT A;  5LIA A;  4LRF A;  1ANI A;  3BDF A;  2ANH A;  3M8W A;  4CYR A;  4CXK A;  1E33 P;  1AJA A;  3ED4 A;  3T02 A;  2ZKT A;  4ZGA A;  5C66 A;  4LR8 A;  4KJD A;  3DPC A;  4FDJ A;  4QAX A;  5KXA A;  5TJ3 A;  1Y6V A;  4LR7 A;  3BDG A;  3UN3 A;  1KHL A;  3B5Q A;  3SZY A;  1ELY A;  5LRM A;  1ED9 A;  1N2K A;  2W8D A;  3TG0 A;  3UN2 A;  4KJG A;  4CXU A;  2W5T A;  3CMR A;  1KHJ A;  4UPL A;  1AJC A;  4LRC A;  5DLV A;  2QZU A;  4LRD A;  5L0K A;  4GTY A;  3TWZ A;  3T01 A;  3NKM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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