3IGYB

Crystal structures of leishmania mexicana phosphoglycerate mutase at high cobalt concentrations
Total Genus 205
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
205
Knots found
sequence length
549
structure length
549
Chain Sequence
LLLKPHKDLPRRTVLIVVMDGLGIGPEDDYDAVHMASTPFMDAHRRDNRHFRCVRAHGTAVGLPTDADMGNSEVGHNALGAGRVALQGASLVDDAIKSGEIYTGEGYRYLHGAFSKEGSTLHLIGLLSDGGVHSRDNQIYSIIEHAVKDGAKRIRVHALYDGRDVPDGSSFRFTDELEAVLAKVRQNGCDAAIASGGGRMFVTMDRYDADWSIVERGWRAQVLGDARHFHSAKEAITTFREEDPKVTDQYYPPFIVVDEQDKPLGTIEDGDAVLCVNFRGDRVIEMTRAFEDEDFNKFDRVRVPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRVSEEYLCGSGLNIFACSETQKFGHVTYFWNGNRSGKIDEKHETFKEVPSDRVQFNEKPRMQSAAITEAAIEALKSGMYNVVRINFPNGDMVGHTGDLKATITGVEAVDESLAKLKDAVDSVNGVYIVTADHGNSDDMAQRDKKGKPMKDGNGNVLPLTSHTLSPVPVFIGGAGLDPRVAMRTDLPAAGLANVTATFINLLGFEAPEDYEPSLIYVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Cofactor-independent phosphoglycerate mutase
publication title Crystal structures of Leishmania mexicana phosphoglycerate mutase suggest a one-metal mechanism and a new enzyme subclass
pubmed doi rcsb
source organism Leishmania mexicana
molecule tags Isomerase
total genus 205
structure length 549
sequence length 549
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2009-07-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01676 Metalloenzyme Metalloenzyme superfamily
B PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3igyB01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 3igyB02
4KJDA 1Y7AA 1AJDA 3BDFA 4CYSA 1URAA 1EW9A 1KHNA 5L0KA 1EQJA 2QZUA 4MIVA 2W8DA 4LRAA 1Y6VA 2GA3A 5KXAA 1KHJA 3A52A 3MK0A 2W5SA 1EI6A 3M7VA 3BDHA 1HQAA 1B8JA 1P49A 1ED8A 3MK1A 3LXQA 4GTYA 4CXKA 4MY4A 1ELYA 1KHKA 2GSUA 2GLQA 4UOPA 4ZGAA 2IFYA 3NKOA 5DLTA 3T02A 3TG0A 4LRCA 1N2LA 5C66A 1KHLA 2XR9A 1ELXA 3WAYA 2W5QA 4GTWA 3M8WA 5GRRA 5HRTA 1K7HA 4LREA 1SHNA 4LQYA 3SZYA 3NKPA 2W5WA 1N2KA 4UPHA 3M8YA 1ZEFA 4GTZA 3UN2A 4LRFA 1FSUA 2IUCA 4KM4A 3B5QA 5AJ9A 4NWJA 1SHQA 1E1ZP 3TWZA 1ELZA 1O99A 1EW8A 4LR9A 4LR8A 3UN3A 4LR7A 3IGYB 4LRBA 4UPLA 1EW2A 2ZKTA 5EGEA 4CXSA 5L0BA 1ALHA 3KD8A 3NKNA 4LR2A 3NKQA 5INHA 1E3CP 4ZG9A 5K4PA 1O98A 2W5RA 3BDGA 2W8SA 4KAVA 4NWXA 5LRNA 5EGHA 1URBA 1ANIA 1ALJA 2RH6A 1HDHA 3WAVA 2W5TA 2IUCB 3CMRA 4N7TA 1AJCA 3TX0A 1ANJA 5DLVA 1ALIA 5IJQA 4QAXA 4GTXA 3WBHA 3Q3QA 1EJJA 1KH7A 4CYRA 5L0EA 3ED4A 4B56A 2W5VA 3NKRA 3OT9A 2GSOA 2VQRA 5LQQA 1KH5A 3DYCA 3WAWA 2W5XA 3UNYA 2XRGA 4FDIA 4UOOA 3SZZA 1ZEDA 2ANHA 5DLWA 3IDDA 1ALKA 5IJSA 1AJBA 3T00A 1KH4A 3T01A 1HJKA 3MK2A 4UORA 4CXUA 1E33P 3IGZB 4ZG7A 4TN0A 4KJGA 4UPKA 4ZG6A 3E2DA 2G9YA 2GSNA 1E2SP 2D1GA 5LIAA 3UN5A 4LRDA 1KH9A 3NKMA 5LRMA 3WAXA 1AJAA 1ZEBA 3NVLA 4FDJA 5GOVA 4UPIA 1AUKA 4KAYA 3M8ZA 4YR1A 2X98A 3BDGB 3DPCA 4MHXA 3UO0A 5TJ3A 1ED9A
chains in the Genus database with same CATH superfamily
4KJDA 1Y7AA 1AJDA 3BDFA 4CYSA 1URAA 1EW9A 1KHNA 5L0KA 1EQJA 2QZUA 4MIVA 2W8DA 4LRAA 1Y6VA 2GA3A 5KXAA 1KHJA 3A52A 3MK0A 2W5SA 1EI6A 3M7VA 3BDHA 1HQAA 1B8JA 1P49A 1ED8A 3MK1A 3LXQA 4GTYA 4CXKA 4MY4A 1ELYA 1KHKA 2GSUA 2GLQA 4UOPA 4ZGAA 2IFYA 3NKOA 5DLTA 3T02A 3TG0A 4LRCA 1N2LA 5C66A 1KHLA 2XR9A 1ELXA 3WAYA 2W5QA 4GTWA 3M8WA 5GRRA 5HRTA 1K7HA 4LREA 1SHNA 4LQYA 3SZYA 3NKPA 2W5WA 1N2KA 4UPHA 3M8YA 1ZEFA 4GTZA 3UN2A 4LRFA 1FSUA 2IUCA 4KM4A 3B5QA 5AJ9A 4NWJA 1SHQA 1E1ZP 3TWZA 1ELZA 1O99A 1EW8A 4LR9A 4LR8A 3UN3A 4LR7A 3IGYB 4LRBA 4UPLA 1EW2A 2ZKTA 5EGEA 4CXSA 5L0BA 1ALHA 3KD8A 3NKNA 4LR2A 3NKQA 5INHA 1E3CP 4ZG9A 5K4PA 1O98A 2W5RA 3BDGA 2W8SA 4KAVA 4NWXA 5LRNA 5EGHA 1URBA 1ANIA 1ALJA 2RH6A 1HDHA 3WAVA 2W5TA 2IUCB 3CMRA 4N7TA 1AJCA 3TX0A 1ANJA 5DLVA 1ALIA 5IJQA 4QAXA 4GTXA 3WBHA 3Q3QA 1EJJA 1KH7A 4CYRA 5L0EA 3ED4A 4B56A 2W5VA 3NKRA 3OT9A 2GSOA 2VQRA 5LQQA 1KH5A 3DYCA 3WAWA 2W5XA 3UNYA 2XRGA 4FDIA 4UOOA 3SZZA 1ZEDA 2ANHA 5DLWA 3IDDA 1ALKA 5IJSA 1AJBA 3T00A 1KH4A 3T01A 1HJKA 3MK2A 4UORA 4CXUA 1E33P 3IGZB 4ZG7A 4TN0A 4KJGA 4UPKA 4ZG6A 3E2DA 2G9YA 2GSNA 1E2SP 2D1GA 5LIAA 3UN5A 4LRDA 1KH9A 3NKMA 5LRMA 3WAXA 1AJAA 1ZEBA 3NVLA 4FDJA 5GOVA 4UPIA 1AUKA 4KAYA 3M8ZA 4YR1A 2X98A 3BDGB 3DPCA 4MHXA 3UO0A 5TJ3A 1ED9A
chains in the Genus database with same CATH topology
4KJDA 1Y7AA 1AJDA 3BDFA 4CYSA 1URAA 1EW9A 1KHNA 5L0KA 1EQJA 2QZUA 4MIVA 2W8DA 4LRAA 1Y6VA 2GA3A 5KXAA 1KHJA 3A52A 3MK0A 2W5SA 1EI6A 3M7VA 3BDHA 1HQAA 1B8JA 1P49A 1ED8A 3MK1A 3LXQA 4GTYA 4CXKA 4MY4A 1ELYA 1KHKA 2GSUA 2GLQA 4UOPA 4ZGAA 2IFYA 3NKOA 5DLTA 3T02A 3TG0A 4LRCA 1N2LA 5C66A 1KHLA 2XR9A 1ELXA 3WAYA 2W5QA 4GTWA 3M8WA 5GRRA 5HRTA 1K7HA 4LREA 1SHNA 4LQYA 3SZYA 3NKPA 2W5WA 1N2KA 4UPHA 3M8YA 1ZEFA 4GTZA 3UN2A 4LRFA 1FSUA 2IUCA 4KM4A 3B5QA 5AJ9A 4NWJA 1SHQA 1E1ZP 3TWZA 1ELZA 1O99A 1EW8A 4LR9A 4LR8A 3UN3A 4LR7A 3IGYB 4LRBA 4UPLA 1EW2A 2ZKTA 5EGEA 4CXSA 5L0BA 1ALHA 3KD8A 3NKNA 4LR2A 3NKQA 5INHA 1E3CP 4ZG9A 5K4PA 1O98A 2W5RA 3BDGA 2W8SA 4KAVA 4NWXA 5LRNA 5EGHA 1URBA 1ANIA 1ALJA 2RH6A 1HDHA 3WAVA 2W5TA 2IUCB 3CMRA 4N7TA 1AJCA 3TX0A 1ANJA 5DLVA 1ALIA 5IJQA 4QAXA 4GTXA 3WBHA 3Q3QA 1EJJA 1KH7A 4CYRA 5L0EA 3ED4A 4B56A 2W5VA 3NKRA 3OT9A 2GSOA 2VQRA 5LQQA 1KH5A 3DYCA 3WAWA 2W5XA 3UNYA 2XRGA 4FDIA 4UOOA 3SZZA 1ZEDA 2ANHA 5DLWA 3IDDA 1ALKA 5IJSA 1AJBA 3T00A 1KH4A 3T01A 1HJKA 3MK2A 4UORA 4CXUA 1E33P 3IGZB 4ZG7A 4TN0A 4KJGA 4UPKA 4ZG6A 3E2DA 2G9YA 2GSNA 1E2SP 2D1GA 5LIAA 3UN5A 4LRDA 1KH9A 3NKMA 5LRMA 3WAXA 1AJAA 1ZEBA 3NVLA 4FDJA 5GOVA 4UPIA 1AUKA 4KAYA 3M8ZA 4YR1A 2X98A 3BDGB 3DPCA 4MHXA 3UO0A 5TJ3A 1ED9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KJD A;  1Y7A A;  1AJD A;  3BDF A;  4CYS A;  1URA A;  1EW9 A;  1KHN A;  5L0K A;  1EQJ A;  2QZU A;  4MIV A;  2W8D A;  4LRA A;  1Y6V A;  2GA3 A;  5KXA A;  1KHJ A;  3A52 A;  3MK0 A;  2W5S A;  1EI6 A;  3M7V A;  3BDH A;  1HQA A;  1B8J A;  1P49 A;  1ED8 A;  3MK1 A;  3LXQ A;  4GTY A;  4CXK A;  4MY4 A;  1ELY A;  1KHK A;  2GSU A;  2GLQ A;  4UOP A;  4ZGA A;  2IFY A;  3NKO A;  5DLT A;  3T02 A;  3TG0 A;  4LRC A;  1N2L A;  5C66 A;  1KHL A;  2XR9 A;  1ELX A;  3WAY A;  2W5Q A;  4GTW A;  3M8W A;  5GRR A;  5HRT A;  1K7H A;  4LRE A;  1SHN A;  4LQY A;  3SZY A;  3NKP A;  2W5W A;  1N2K A;  4UPH A;  3M8Y A;  1ZEF A;  4GTZ A;  3UN2 A;  4LRF A;  1FSU A;  2IUC A;  4KM4 A;  3B5Q A;  5AJ9 A;  4NWJ A;  1SHQ A;  1E1Z P;  3TWZ A;  1ELZ A;  1O99 A;  1EW8 A;  4LR9 A;  4LR8 A;  3UN3 A;  4LR7 A;  3IGY B;  4LRB A;  4UPL A;  1EW2 A;  2ZKT A;  5EGE A;  4CXS A;  5L0B A;  1ALH A;  3KD8 A;  3NKN A;  4LR2 A;  3NKQ A;  5INH A;  1E3C P;  4ZG9 A;  5K4P A;  1O98 A;  2W5R A;  3BDG A;  2W8S A;  4KAV A;  4NWX A;  5LRN A;  5EGH A;  1URB A;  1ANI A;  1ALJ A;  2RH6 A;  1HDH A;  3WAV A;  2W5T A;  2IUC B;  3CMR A;  4N7T A;  1AJC A;  3TX0 A;  1ANJ A;  5DLV A;  1ALI A;  5IJQ A;  4QAX A;  4GTX A;  3WBH A;  3Q3Q A;  1EJJ A;  1KH7 A;  4CYR A;  5L0E A;  3ED4 A;  4B56 A;  2W5V A;  3NKR A;  3OT9 A;  2GSO A;  2VQR A;  5LQQ A;  1KH5 A;  3DYC A;  3WAW A;  2W5X A;  3UNY A;  2XRG A;  4FDI A;  4UOO A;  3SZZ A;  1ZED A;  2ANH A;  5DLW A;  3IDD A;  1ALK A;  5IJS A;  1AJB A;  3T00 A;  1KH4 A;  3T01 A;  1HJK A;  3MK2 A;  4UOR A;  4CXU A;  1E33 P;  3IGZ B;  4ZG7 A;  4TN0 A;  4KJG A;  4UPK A;  4ZG6 A;  3E2D A;  2G9Y A;  2GSN A;  1E2S P;  2D1G A;  5LIA A;  3UN5 A;  4LRD A;  1KH9 A;  3NKM A;  5LRM A;  3WAX A;  1AJA A;  1ZEB A;  3NVL A;  4FDJ A;  5GOV A;  4UPI A;  1AUK A;  4KAY A;  3M8Z A;  4YR1 A;  2X98 A;  3BDG B;  3DPC A;  4MHX A;  3UO0 A;  5TJ3 A;  1ED9 A; 
#chains in the Genus database with same CATH topology
 4KJD A;  1Y7A A;  1AJD A;  3BDF A;  4CYS A;  1URA A;  1EW9 A;  1KHN A;  5L0K A;  1EQJ A;  2QZU A;  4MIV A;  2W8D A;  4LRA A;  1Y6V A;  2GA3 A;  5KXA A;  1KHJ A;  3A52 A;  3MK0 A;  2W5S A;  1EI6 A;  3M7V A;  3BDH A;  1HQA A;  1B8J A;  1P49 A;  1ED8 A;  3MK1 A;  3LXQ A;  4GTY A;  4CXK A;  4MY4 A;  1ELY A;  1KHK A;  2GSU A;  2GLQ A;  4UOP A;  4ZGA A;  2IFY A;  3NKO A;  5DLT A;  3T02 A;  3TG0 A;  4LRC A;  1N2L A;  5C66 A;  1KHL A;  2XR9 A;  1ELX A;  3WAY A;  2W5Q A;  4GTW A;  3M8W A;  5GRR A;  5HRT A;  1K7H A;  4LRE A;  1SHN A;  4LQY A;  3SZY A;  3NKP A;  2W5W A;  1N2K A;  4UPH A;  3M8Y A;  1ZEF A;  4GTZ A;  3UN2 A;  4LRF A;  1FSU A;  2IUC A;  4KM4 A;  3B5Q A;  5AJ9 A;  4NWJ A;  1SHQ A;  1E1Z P;  3TWZ A;  1ELZ A;  1O99 A;  1EW8 A;  4LR9 A;  4LR8 A;  3UN3 A;  4LR7 A;  3IGY B;  4LRB A;  4UPL A;  1EW2 A;  2ZKT A;  5EGE A;  4CXS A;  5L0B A;  1ALH A;  3KD8 A;  3NKN A;  4LR2 A;  3NKQ A;  5INH A;  1E3C P;  4ZG9 A;  5K4P A;  1O98 A;  2W5R A;  3BDG A;  2W8S A;  4KAV A;  4NWX A;  5LRN A;  5EGH A;  1URB A;  1ANI A;  1ALJ A;  2RH6 A;  1HDH A;  3WAV A;  2W5T A;  2IUC B;  3CMR A;  4N7T A;  1AJC A;  3TX0 A;  1ANJ A;  5DLV A;  1ALI A;  5IJQ A;  4QAX A;  4GTX A;  3WBH A;  3Q3Q A;  1EJJ A;  1KH7 A;  4CYR A;  5L0E A;  3ED4 A;  4B56 A;  2W5V A;  3NKR A;  3OT9 A;  2GSO A;  2VQR A;  5LQQ A;  1KH5 A;  3DYC A;  3WAW A;  2W5X A;  3UNY A;  2XRG A;  4FDI A;  4UOO A;  3SZZ A;  1ZED A;  2ANH A;  5DLW A;  3IDD A;  1ALK A;  5IJS A;  1AJB A;  3T00 A;  1KH4 A;  3T01 A;  1HJK A;  3MK2 A;  4UOR A;  4CXU A;  1E33 P;  3IGZ B;  4ZG7 A;  4TN0 A;  4KJG A;  4UPK A;  4ZG6 A;  3E2D A;  2G9Y A;  2GSN A;  1E2S P;  2D1G A;  5LIA A;  3UN5 A;  4LRD A;  1KH9 A;  3NKM A;  5LRM A;  3WAX A;  1AJA A;  1ZEB A;  3NVL A;  4FDJ A;  5GOV A;  4UPI A;  1AUK A;  4KAY A;  3M8Z A;  4YR1 A;  2X98 A;  3BDG B;  3DPC A;  4MHX A;  3UO0 A;  5TJ3 A;  1ED9 A; 
#chains in the Genus database with same CATH homology
 4KJD A;  1Y7A A;  1AJD A;  3BDF A;  4CYS A;  1URA A;  1EW9 A;  1KHN A;  5L0K A;  1EQJ A;  2QZU A;  4MIV A;  2W8D A;  4LRA A;  1Y6V A;  2GA3 A;  5KXA A;  1KHJ A;  3A52 A;  3MK0 A;  2W5S A;  1EI6 A;  3M7V A;  3BDH A;  1HQA A;  1B8J A;  1P49 A;  1ED8 A;  3MK1 A;  3LXQ A;  4GTY A;  4CXK A;  4MY4 A;  1ELY A;  1KHK A;  2GSU A;  2GLQ A;  4UOP A;  4ZGA A;  2IFY A;  3NKO A;  5DLT A;  3T02 A;  3TG0 A;  4LRC A;  1N2L A;  5C66 A;  1KHL A;  2XR9 A;  1ELX A;  3WAY A;  2W5Q A;  4GTW A;  3M8W A;  5GRR A;  5HRT A;  1K7H A;  4LRE A;  1SHN A;  4LQY A;  3SZY A;  3NKP A;  2W5W A;  1N2K A;  4UPH A;  3M8Y A;  1ZEF A;  4GTZ A;  3UN2 A;  4LRF A;  1FSU A;  2IUC A;  4KM4 A;  3B5Q A;  5AJ9 A;  4NWJ A;  1SHQ A;  1E1Z P;  3TWZ A;  1ELZ A;  1O99 A;  1EW8 A;  4LR9 A;  4LR8 A;  3UN3 A;  4LR7 A;  3IGY B;  4LRB A;  4UPL A;  1EW2 A;  2ZKT A;  5EGE A;  4CXS A;  5L0B A;  1ALH A;  3KD8 A;  3NKN A;  4LR2 A;  3NKQ A;  5INH A;  1E3C P;  4ZG9 A;  5K4P A;  1O98 A;  2W5R A;  3BDG A;  2W8S A;  4KAV A;  4NWX A;  5LRN A;  5EGH A;  1URB A;  1ANI A;  1ALJ A;  2RH6 A;  1HDH A;  3WAV A;  2W5T A;  2IUC B;  3CMR A;  4N7T A;  1AJC A;  3TX0 A;  1ANJ A;  5DLV A;  1ALI A;  5IJQ A;  4QAX A;  4GTX A;  3WBH A;  3Q3Q A;  1EJJ A;  1KH7 A;  4CYR A;  5L0E A;  3ED4 A;  4B56 A;  2W5V A;  3NKR A;  3OT9 A;  2GSO A;  2VQR A;  5LQQ A;  1KH5 A;  3DYC A;  3WAW A;  2W5X A;  3UNY A;  2XRG A;  4FDI A;  4UOO A;  3SZZ A;  1ZED A;  2ANH A;  5DLW A;  3IDD A;  1ALK A;  5IJS A;  1AJB A;  3T00 A;  1KH4 A;  3T01 A;  1HJK A;  3MK2 A;  4UOR A;  4CXU A;  1E33 P;  3IGZ B;  4ZG7 A;  4TN0 A;  4KJG A;  4UPK A;  4ZG6 A;  3E2D A;  2G9Y A;  2GSN A;  1E2S P;  2D1G A;  5LIA A;  3UN5 A;  4LRD A;  1KH9 A;  3NKM A;  5LRM A;  3WAX A;  1AJA A;  1ZEB A;  3NVL A;  4FDJ A;  5GOV A;  4UPI A;  1AUK A;  4KAY A;  3M8Z A;  4YR1 A;  2X98 A;  3BDG B;  3DPC A;  4MHX A;  3UO0 A;  5TJ3 A;  1ED9 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...