4NWXA

Crystal structure of phosphoglycerate mutase from staphylococcus aureus in 2-phosphoglyceric acid bound form
Total Genus 194
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
Knots found
sequence length
503
structure length
503
Chain Sequence
KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
publication title Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism
pubmed doi rcsb
source organism Staphylococcus aureus subsp. aureus
molecule tags Isomerase
total genus 194
structure length 503
sequence length 503
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2013-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4nwxA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 4nwxA02
3WAVA 5GOVA 3T01A 3IDDA 5AJ9A 1ZEFA 1SHQA 4GTXA 3M8YA 3NKPA 4UOPA 5DLWA 4UOOA 1E33P 1KHJA 3UNYA 3NKRA 1E1ZP 1ZEDA 3ED4A 4CYRA 3DPCA 2G9YA 1O99A 4LR7A 1P49A 3OT9A 3T02A 4NWJA 1AJCA 3CMRA 3UN3A 1KH9A 2IUCA 1E2SP 2W8DA 2W5XA 3BDFA 1KHNA 1ED9A 3NKMA 5C66A 3UO0A 2GSUA 5LRMA 3WAXA 1ELZA 1E3CP 2W5TA 1EW8A 2XR9A 1ANJA 1ALKA 4ZGAA 2XRGA 4B56A 5KXAA 4LQYA 4LRDA 2ZKTA 4UORA 2QZUA 4UPIA 3T00A 5LQQA 4LR9A 5EGHA 3WAYA 4LRAA 4ZG6A 4CXKA 4ZG7A 4FDJA 1Y6VA 1AJAA 5L0EA 4KAVA 1ALHA 5LRNA 3IGZB 5INHA 1FSUA 2W5RA 1N2LA 4QAXA 4KAYA 1URAA 4LRFA 4FDIA 5L0BA 4GTYA 5K4PA 3TX0A 5IJSA 3M7VA 2W8SA 1EW2A 4KM4A 2W5WA 1ALJA 5LIAA 5TJ3A 1ED8A 1N2KA 5DLVA 1AUKA 4CXSA 2W5QA 5IJQA 4CXUA 1EJJA 2X98A 3Q3QA 1AJBA 1URBA 4LRBA 5GRRA 3BDGB 5EGEA 3NKOA 1HQAA 1KHLA 3MK1A 2GLQA 4LR8A 3E2DA 1O98A 2VQRA 3NKQA 1HJKA 2IFYA 3DYCA 4LR2A 4MHXA 4N7TA 4NWXA 3A52A 1ZEBA 5L0KA 4MIVA 1ELYA 3UN2A 1ANIA 3M8WA 1B8JA 3SZYA 4YR1A 5DLTA 3TWZA 1ALIA 3IGYB 4ZG9A 5HRTA 1AJDA 1EW9A 2GSOA 1EQJA 1SHNA 1EI6A 3BDGA 4GTZA 2ANHA 3UN5A 3SZZA 1KH7A 2W5SA 3B5QA 3NKNA 2GSNA 3KD8A 1KH5A 4UPHA 2D1GA 4MY4A 3M8ZA 3WBHA 2RH6A 4CYSA 1Y7AA 4KJGA 1K7HA 3MK0A 4LREA 3TG0A 3WAWA 4UPLA 3LXQA 3BDHA 1KHKA 2GA3A 1ELXA 4TN0A 3NVLA 1KH4A 4UPKA 4LRCA 2W5VA 3MK2A 4KJDA 1HDHA 2IUCB 4GTWA
chains in the Genus database with same CATH superfamily
3WAVA 5GOVA 3T01A 3IDDA 5AJ9A 1ZEFA 1SHQA 4GTXA 3M8YA 3NKPA 4UOPA 5DLWA 4UOOA 1E33P 1KHJA 3UNYA 3NKRA 1E1ZP 1ZEDA 3ED4A 4CYRA 3DPCA 2G9YA 1O99A 4LR7A 1P49A 3OT9A 3T02A 4NWJA 1AJCA 3CMRA 3UN3A 1KH9A 2IUCA 1E2SP 2W8DA 2W5XA 3BDFA 1KHNA 1ED9A 3NKMA 5C66A 3UO0A 2GSUA 5LRMA 3WAXA 1ELZA 1E3CP 2W5TA 1EW8A 2XR9A 1ANJA 1ALKA 4ZGAA 2XRGA 4B56A 5KXAA 4LQYA 4LRDA 2ZKTA 4UORA 2QZUA 4UPIA 3T00A 5LQQA 4LR9A 5EGHA 3WAYA 4LRAA 4ZG6A 4CXKA 4ZG7A 4FDJA 1Y6VA 1AJAA 5L0EA 4KAVA 1ALHA 5LRNA 3IGZB 5INHA 1FSUA 2W5RA 1N2LA 4QAXA 4KAYA 1URAA 4LRFA 4FDIA 5L0BA 4GTYA 5K4PA 3TX0A 5IJSA 3M7VA 2W8SA 1EW2A 4KM4A 2W5WA 1ALJA 5LIAA 5TJ3A 1ED8A 1N2KA 5DLVA 1AUKA 4CXSA 2W5QA 5IJQA 4CXUA 1EJJA 2X98A 3Q3QA 1AJBA 1URBA 4LRBA 5GRRA 3BDGB 5EGEA 3NKOA 1HQAA 1KHLA 3MK1A 2GLQA 4LR8A 3E2DA 1O98A 2VQRA 3NKQA 1HJKA 2IFYA 3DYCA 4LR2A 4MHXA 4N7TA 4NWXA 3A52A 1ZEBA 5L0KA 4MIVA 1ELYA 3UN2A 1ANIA 3M8WA 1B8JA 3SZYA 4YR1A 5DLTA 3TWZA 1ALIA 3IGYB 4ZG9A 5HRTA 1AJDA 1EW9A 2GSOA 1EQJA 1SHNA 1EI6A 3BDGA 4GTZA 2ANHA 3UN5A 3SZZA 1KH7A 2W5SA 3B5QA 3NKNA 2GSNA 3KD8A 1KH5A 4UPHA 2D1GA 4MY4A 3M8ZA 3WBHA 2RH6A 4CYSA 1Y7AA 4KJGA 1K7HA 3MK0A 4LREA 3TG0A 3WAWA 4UPLA 3LXQA 3BDHA 1KHKA 2GA3A 1ELXA 4TN0A 3NVLA 1KH4A 4UPKA 4LRCA 2W5VA 3MK2A 4KJDA 1HDHA 2IUCB 4GTWA
chains in the Genus database with same CATH topology
3WAVA 5GOVA 3T01A 3IDDA 5AJ9A 1ZEFA 1SHQA 4GTXA 3M8YA 3NKPA 4UOPA 5DLWA 4UOOA 1E33P 1KHJA 3UNYA 3NKRA 1E1ZP 1ZEDA 3ED4A 4CYRA 3DPCA 2G9YA 1O99A 4LR7A 1P49A 3OT9A 3T02A 4NWJA 1AJCA 3CMRA 3UN3A 1KH9A 2IUCA 1E2SP 2W8DA 2W5XA 3BDFA 1KHNA 1ED9A 3NKMA 5C66A 3UO0A 2GSUA 5LRMA 3WAXA 1ELZA 1E3CP 2W5TA 1EW8A 2XR9A 1ANJA 1ALKA 4ZGAA 2XRGA 4B56A 5KXAA 4LQYA 4LRDA 2ZKTA 4UORA 2QZUA 4UPIA 3T00A 5LQQA 4LR9A 5EGHA 3WAYA 4LRAA 4ZG6A 4CXKA 4ZG7A 4FDJA 1Y6VA 1AJAA 5L0EA 4KAVA 1ALHA 5LRNA 3IGZB 5INHA 1FSUA 2W5RA 1N2LA 4QAXA 4KAYA 1URAA 4LRFA 4FDIA 5L0BA 4GTYA 5K4PA 3TX0A 5IJSA 3M7VA 2W8SA 1EW2A 4KM4A 2W5WA 1ALJA 5LIAA 5TJ3A 1ED8A 1N2KA 5DLVA 1AUKA 4CXSA 2W5QA 5IJQA 4CXUA 1EJJA 2X98A 3Q3QA 1AJBA 1URBA 4LRBA 5GRRA 3BDGB 5EGEA 3NKOA 1HQAA 1KHLA 3MK1A 2GLQA 4LR8A 3E2DA 1O98A 2VQRA 3NKQA 1HJKA 2IFYA 3DYCA 4LR2A 4MHXA 4N7TA 4NWXA 3A52A 1ZEBA 5L0KA 4MIVA 1ELYA 3UN2A 1ANIA 3M8WA 1B8JA 3SZYA 4YR1A 5DLTA 3TWZA 1ALIA 3IGYB 4ZG9A 5HRTA 1AJDA 1EW9A 2GSOA 1EQJA 1SHNA 1EI6A 3BDGA 4GTZA 2ANHA 3UN5A 3SZZA 1KH7A 2W5SA 3B5QA 3NKNA 2GSNA 3KD8A 1KH5A 4UPHA 2D1GA 4MY4A 3M8ZA 3WBHA 2RH6A 4CYSA 1Y7AA 4KJGA 1K7HA 3MK0A 4LREA 3TG0A 3WAWA 4UPLA 3LXQA 3BDHA 1KHKA 2GA3A 1ELXA 4TN0A 3NVLA 1KH4A 4UPKA 4LRCA 2W5VA 3MK2A 4KJDA 1HDHA 2IUCB 4GTWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WAV A;  5GOV A;  3T01 A;  3IDD A;  5AJ9 A;  1ZEF A;  1SHQ A;  4GTX A;  3M8Y A;  3NKP A;  4UOP A;  5DLW A;  4UOO A;  1E33 P;  1KHJ A;  3UNY A;  3NKR A;  1E1Z P;  1ZED A;  3ED4 A;  4CYR A;  3DPC A;  2G9Y A;  1O99 A;  4LR7 A;  1P49 A;  3OT9 A;  3T02 A;  4NWJ A;  1AJC A;  3CMR A;  3UN3 A;  1KH9 A;  2IUC A;  1E2S P;  2W8D A;  2W5X A;  3BDF A;  1KHN A;  1ED9 A;  3NKM A;  5C66 A;  3UO0 A;  2GSU A;  5LRM A;  3WAX A;  1ELZ A;  1E3C P;  2W5T A;  1EW8 A;  2XR9 A;  1ANJ A;  1ALK A;  4ZGA A;  2XRG A;  4B56 A;  5KXA A;  4LQY A;  4LRD A;  2ZKT A;  4UOR A;  2QZU A;  4UPI A;  3T00 A;  5LQQ A;  4LR9 A;  5EGH A;  3WAY A;  4LRA A;  4ZG6 A;  4CXK A;  4ZG7 A;  4FDJ A;  1Y6V A;  1AJA A;  5L0E A;  4KAV A;  1ALH A;  5LRN A;  3IGZ B;  5INH A;  1FSU A;  2W5R A;  1N2L A;  4QAX A;  4KAY A;  1URA A;  4LRF A;  4FDI A;  5L0B A;  4GTY A;  5K4P A;  3TX0 A;  5IJS A;  3M7V A;  2W8S A;  1EW2 A;  4KM4 A;  2W5W A;  1ALJ A;  5LIA A;  5TJ3 A;  1ED8 A;  1N2K A;  5DLV A;  1AUK A;  4CXS A;  2W5Q A;  5IJQ A;  4CXU A;  1EJJ A;  2X98 A;  3Q3Q A;  1AJB A;  1URB A;  4LRB A;  5GRR A;  3BDG B;  5EGE A;  3NKO A;  1HQA A;  1KHL A;  3MK1 A;  2GLQ A;  4LR8 A;  3E2D A;  1O98 A;  2VQR A;  3NKQ A;  1HJK A;  2IFY A;  3DYC A;  4LR2 A;  4MHX A;  4N7T A;  4NWX A;  3A52 A;  1ZEB A;  5L0K A;  4MIV A;  1ELY A;  3UN2 A;  1ANI A;  3M8W A;  1B8J A;  3SZY A;  4YR1 A;  5DLT A;  3TWZ A;  1ALI A;  3IGY B;  4ZG9 A;  5HRT A;  1AJD A;  1EW9 A;  2GSO A;  1EQJ A;  1SHN A;  1EI6 A;  3BDG A;  4GTZ A;  2ANH A;  3UN5 A;  3SZZ A;  1KH7 A;  2W5S A;  3B5Q A;  3NKN A;  2GSN A;  3KD8 A;  1KH5 A;  4UPH A;  2D1G A;  4MY4 A;  3M8Z A;  3WBH A;  2RH6 A;  4CYS A;  1Y7A A;  4KJG A;  1K7H A;  3MK0 A;  4LRE A;  3TG0 A;  3WAW A;  4UPL A;  3LXQ A;  3BDH A;  1KHK A;  2GA3 A;  1ELX A;  4TN0 A;  3NVL A;  1KH4 A;  4UPK A;  4LRC A;  2W5V A;  3MK2 A;  4KJD A;  1HDH A;  2IUC B;  4GTW A; 
#chains in the Genus database with same CATH topology
 3WAV A;  5GOV A;  3T01 A;  3IDD A;  5AJ9 A;  1ZEF A;  1SHQ A;  4GTX A;  3M8Y A;  3NKP A;  4UOP A;  5DLW A;  4UOO A;  1E33 P;  1KHJ A;  3UNY A;  3NKR A;  1E1Z P;  1ZED A;  3ED4 A;  4CYR A;  3DPC A;  2G9Y A;  1O99 A;  4LR7 A;  1P49 A;  3OT9 A;  3T02 A;  4NWJ A;  1AJC A;  3CMR A;  3UN3 A;  1KH9 A;  2IUC A;  1E2S P;  2W8D A;  2W5X A;  3BDF A;  1KHN A;  1ED9 A;  3NKM A;  5C66 A;  3UO0 A;  2GSU A;  5LRM A;  3WAX A;  1ELZ A;  1E3C P;  2W5T A;  1EW8 A;  2XR9 A;  1ANJ A;  1ALK A;  4ZGA A;  2XRG A;  4B56 A;  5KXA A;  4LQY A;  4LRD A;  2ZKT A;  4UOR A;  2QZU A;  4UPI A;  3T00 A;  5LQQ A;  4LR9 A;  5EGH A;  3WAY A;  4LRA A;  4ZG6 A;  4CXK A;  4ZG7 A;  4FDJ A;  1Y6V A;  1AJA A;  5L0E A;  4KAV A;  1ALH A;  5LRN A;  3IGZ B;  5INH A;  1FSU A;  2W5R A;  1N2L A;  4QAX A;  4KAY A;  1URA A;  4LRF A;  4FDI A;  5L0B A;  4GTY A;  5K4P A;  3TX0 A;  5IJS A;  3M7V A;  2W8S A;  1EW2 A;  4KM4 A;  2W5W A;  1ALJ A;  5LIA A;  5TJ3 A;  1ED8 A;  1N2K A;  5DLV A;  1AUK A;  4CXS A;  2W5Q A;  5IJQ A;  4CXU A;  1EJJ A;  2X98 A;  3Q3Q A;  1AJB A;  1URB A;  4LRB A;  5GRR A;  3BDG B;  5EGE A;  3NKO A;  1HQA A;  1KHL A;  3MK1 A;  2GLQ A;  4LR8 A;  3E2D A;  1O98 A;  2VQR A;  3NKQ A;  1HJK A;  2IFY A;  3DYC A;  4LR2 A;  4MHX A;  4N7T A;  4NWX A;  3A52 A;  1ZEB A;  5L0K A;  4MIV A;  1ELY A;  3UN2 A;  1ANI A;  3M8W A;  1B8J A;  3SZY A;  4YR1 A;  5DLT A;  3TWZ A;  1ALI A;  3IGY B;  4ZG9 A;  5HRT A;  1AJD A;  1EW9 A;  2GSO A;  1EQJ A;  1SHN A;  1EI6 A;  3BDG A;  4GTZ A;  2ANH A;  3UN5 A;  3SZZ A;  1KH7 A;  2W5S A;  3B5Q A;  3NKN A;  2GSN A;  3KD8 A;  1KH5 A;  4UPH A;  2D1G A;  4MY4 A;  3M8Z A;  3WBH A;  2RH6 A;  4CYS A;  1Y7A A;  4KJG A;  1K7H A;  3MK0 A;  4LRE A;  3TG0 A;  3WAW A;  4UPL A;  3LXQ A;  3BDH A;  1KHK A;  2GA3 A;  1ELX A;  4TN0 A;  3NVL A;  1KH4 A;  4UPK A;  4LRC A;  2W5V A;  3MK2 A;  4KJD A;  1HDH A;  2IUC B;  4GTW A; 
#chains in the Genus database with same CATH homology
 3WAV A;  5GOV A;  3T01 A;  3IDD A;  5AJ9 A;  1ZEF A;  1SHQ A;  4GTX A;  3M8Y A;  3NKP A;  4UOP A;  5DLW A;  4UOO A;  1E33 P;  1KHJ A;  3UNY A;  3NKR A;  1E1Z P;  1ZED A;  3ED4 A;  4CYR A;  3DPC A;  2G9Y A;  1O99 A;  4LR7 A;  1P49 A;  3OT9 A;  3T02 A;  4NWJ A;  1AJC A;  3CMR A;  3UN3 A;  1KH9 A;  2IUC A;  1E2S P;  2W8D A;  2W5X A;  3BDF A;  1KHN A;  1ED9 A;  3NKM A;  5C66 A;  3UO0 A;  2GSU A;  5LRM A;  3WAX A;  1ELZ A;  1E3C P;  2W5T A;  1EW8 A;  2XR9 A;  1ANJ A;  1ALK A;  4ZGA A;  2XRG A;  4B56 A;  5KXA A;  4LQY A;  4LRD A;  2ZKT A;  4UOR A;  2QZU A;  4UPI A;  3T00 A;  5LQQ A;  4LR9 A;  5EGH A;  3WAY A;  4LRA A;  4ZG6 A;  4CXK A;  4ZG7 A;  4FDJ A;  1Y6V A;  1AJA A;  5L0E A;  4KAV A;  1ALH A;  5LRN A;  3IGZ B;  5INH A;  1FSU A;  2W5R A;  1N2L A;  4QAX A;  4KAY A;  1URA A;  4LRF A;  4FDI A;  5L0B A;  4GTY A;  5K4P A;  3TX0 A;  5IJS A;  3M7V A;  2W8S A;  1EW2 A;  4KM4 A;  2W5W A;  1ALJ A;  5LIA A;  5TJ3 A;  1ED8 A;  1N2K A;  5DLV A;  1AUK A;  4CXS A;  2W5Q A;  5IJQ A;  4CXU A;  1EJJ A;  2X98 A;  3Q3Q A;  1AJB A;  1URB A;  4LRB A;  5GRR A;  3BDG B;  5EGE A;  3NKO A;  1HQA A;  1KHL A;  3MK1 A;  2GLQ A;  4LR8 A;  3E2D A;  1O98 A;  2VQR A;  3NKQ A;  1HJK A;  2IFY A;  3DYC A;  4LR2 A;  4MHX A;  4N7T A;  4NWX A;  3A52 A;  1ZEB A;  5L0K A;  4MIV A;  1ELY A;  3UN2 A;  1ANI A;  3M8W A;  1B8J A;  3SZY A;  4YR1 A;  5DLT A;  3TWZ A;  1ALI A;  3IGY B;  4ZG9 A;  5HRT A;  1AJD A;  1EW9 A;  2GSO A;  1EQJ A;  1SHN A;  1EI6 A;  3BDG A;  4GTZ A;  2ANH A;  3UN5 A;  3SZZ A;  1KH7 A;  2W5S A;  3B5Q A;  3NKN A;  2GSN A;  3KD8 A;  1KH5 A;  4UPH A;  2D1G A;  4MY4 A;  3M8Z A;  3WBH A;  2RH6 A;  4CYS A;  1Y7A A;  4KJG A;  1K7H A;  3MK0 A;  4LRE A;  3TG0 A;  3WAW A;  4UPL A;  3LXQ A;  3BDH A;  1KHK A;  2GA3 A;  1ELX A;  4TN0 A;  3NVL A;  1KH4 A;  4UPK A;  4LRC A;  2W5V A;  3MK2 A;  4KJD A;  1HDH A;  2IUC B;  4GTW A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...