4NWXA

Crystal structure of phosphoglycerate mutase from staphylococcus aureus in 2-phosphoglyceric acid bound form
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
Knots found
sequence length
503
structure length
503
Chain Sequence
KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
publication title Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism
pubmed doi rcsb
source organism Staphylococcus aureus subsp. aureus
molecule tags Isomerase
total genus 194
structure length 503
sequence length 503
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2013-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4nwxA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 4nwxA02
4GTYA 1ED8A 1KH9A 1ALJA 3T02A 3A52A 1FSUA 3BDHA 3NKOA 1AJCA 2QZUA 4N7TA 1O99A 4UPKA 4CXUA 4LR9A 2W5XA 4LR7A 1EW8A 2X98A 3Q3QA 1ALHA 4UOOA 2G9YA 4CXKA 3UN3A 4FDIA 4QAXA 2ZKTA 1AUKA 1SHQA 1ELXA 2IUCA 4KAVA 4CXSA 3UN2A 4LREA 5LIAA 3T01A 3E2DA 3SZZA 1ALIA 5C66A 2IFYA 1KH4A 3MK0A 1ED9A 4LRBA 2GLQA 4UORA 1ZEFA 1E33P 2W5QA 2D1GA 3B5QA 3T00A 3WAWA 4UPHA 1E2SP 4GTWA 3SZYA 5IJQA 3ED4A 2ANHA 4LRAA 4YR1A 2W5SA 1EI6A 1B8JA 4KJGA 3MK2A 5AJ9A 2W8DA 3LXQA 3NKRA 4UPIA 3NVLA 3M8YA 4MHXA 2IUCB 2W5VA 2W5WA 3IDDA 2GA3A 4NWXA 1N2KA 4LRDA 4ZG7A 1E3CP 2GSNA 3IGYB 1KHLA 4FDJA 1URAA 4B56A 4LQYA 1O98A 1ELZA 4CYSA 2W8SA 2GSOA 2W5TA 1KHJA 3NKQA 3M8ZA 1HQAA 4UPLA 5L0KA 1Y6VA 2VQRA 3BDFA 4MY4A 3OT9A 5EGEA 3DPCA 3UNYA 5IJSA 4LRCA 1EW9A 5DLVA 1N2LA 3TWZA 5DLTA 5L0EA 5L0BA 3WAXA 5DLWA 4ZG9A 1ANIA 3CMRA 1URBA 3TG0A 3BDGA 1KH7A 5GRRA 4TN0A 3MK1A 3NKPA 1KH5A 3DYCA 5LQQA 1E1ZP 5HRTA 3UN5A 3WBHA 2RH6A 1SHNA 1AJAA 3KD8A 5TJ3A 1HJKA 1ELYA 1ALKA 1P49A 3UO0A 4CYRA 1ZEBA 3NKNA 3WAYA 1ZEDA 4GTZA 2XRGA 4UOPA 1AJBA 1EQJA 1Y7AA 4ZGAA 3M8WA 1AJDA 5LRNA 3M7VA 4LR2A 5K4PA 5KXAA 4KM4A 4MIVA 2GSUA 1ANJA 5EGHA 1KHKA 4LRFA 3BDGB 1K7HA 3NKMA 4KJDA 2XR9A 1EJJA 2W5RA 4ZG6A 5LRMA 4NWJA 1KHNA 3TX0A 1HDHA 3IGZB 5GOVA 4LR8A 1EW2A 4GTXA 5INHA 4KAYA 3WAVA
chains in the Genus database with same CATH superfamily
4GTYA 1ED8A 1KH9A 1ALJA 3T02A 3A52A 1FSUA 3BDHA 3NKOA 1AJCA 2QZUA 4N7TA 1O99A 4UPKA 4CXUA 4LR9A 2W5XA 4LR7A 1EW8A 2X98A 3Q3QA 1ALHA 4UOOA 2G9YA 4CXKA 3UN3A 4FDIA 4QAXA 2ZKTA 1AUKA 1SHQA 1ELXA 2IUCA 4KAVA 4CXSA 3UN2A 4LREA 5LIAA 3T01A 3E2DA 3SZZA 1ALIA 5C66A 2IFYA 1KH4A 3MK0A 1ED9A 4LRBA 2GLQA 4UORA 1ZEFA 1E33P 2W5QA 2D1GA 3B5QA 3T00A 3WAWA 4UPHA 1E2SP 4GTWA 3SZYA 5IJQA 3ED4A 2ANHA 4LRAA 4YR1A 2W5SA 1EI6A 1B8JA 4KJGA 3MK2A 5AJ9A 2W8DA 3LXQA 3NKRA 4UPIA 3NVLA 3M8YA 4MHXA 2IUCB 2W5VA 2W5WA 3IDDA 2GA3A 4NWXA 1N2KA 4LRDA 4ZG7A 1E3CP 2GSNA 3IGYB 1KHLA 4FDJA 1URAA 4B56A 4LQYA 1O98A 1ELZA 4CYSA 2W8SA 2GSOA 2W5TA 1KHJA 3NKQA 3M8ZA 1HQAA 4UPLA 5L0KA 1Y6VA 2VQRA 3BDFA 4MY4A 3OT9A 5EGEA 3DPCA 3UNYA 5IJSA 4LRCA 1EW9A 5DLVA 1N2LA 3TWZA 5DLTA 5L0EA 5L0BA 3WAXA 5DLWA 4ZG9A 1ANIA 3CMRA 1URBA 3TG0A 3BDGA 1KH7A 5GRRA 4TN0A 3MK1A 3NKPA 1KH5A 3DYCA 5LQQA 1E1ZP 5HRTA 3UN5A 3WBHA 2RH6A 1SHNA 1AJAA 3KD8A 5TJ3A 1HJKA 1ELYA 1ALKA 1P49A 3UO0A 4CYRA 1ZEBA 3NKNA 3WAYA 1ZEDA 4GTZA 2XRGA 4UOPA 1AJBA 1EQJA 1Y7AA 4ZGAA 3M8WA 1AJDA 5LRNA 3M7VA 4LR2A 5K4PA 5KXAA 4KM4A 4MIVA 2GSUA 1ANJA 5EGHA 1KHKA 4LRFA 3BDGB 1K7HA 3NKMA 4KJDA 2XR9A 1EJJA 2W5RA 4ZG6A 5LRMA 4NWJA 1KHNA 3TX0A 1HDHA 3IGZB 5GOVA 4LR8A 1EW2A 4GTXA 5INHA 4KAYA 3WAVA
chains in the Genus database with same CATH topology
4GTYA 1ED8A 1KH9A 1ALJA 3T02A 3A52A 1FSUA 3BDHA 3NKOA 1AJCA 2QZUA 4N7TA 1O99A 4UPKA 4CXUA 4LR9A 2W5XA 4LR7A 1EW8A 2X98A 3Q3QA 1ALHA 4UOOA 2G9YA 4CXKA 3UN3A 4FDIA 4QAXA 2ZKTA 1AUKA 1SHQA 1ELXA 2IUCA 4KAVA 4CXSA 3UN2A 4LREA 5LIAA 3T01A 3E2DA 3SZZA 1ALIA 5C66A 2IFYA 1KH4A 3MK0A 1ED9A 4LRBA 2GLQA 4UORA 1ZEFA 1E33P 2W5QA 2D1GA 3B5QA 3T00A 3WAWA 4UPHA 1E2SP 4GTWA 3SZYA 5IJQA 3ED4A 2ANHA 4LRAA 4YR1A 2W5SA 1EI6A 1B8JA 4KJGA 3MK2A 5AJ9A 2W8DA 3LXQA 3NKRA 4UPIA 3NVLA 3M8YA 4MHXA 2IUCB 2W5VA 2W5WA 3IDDA 2GA3A 4NWXA 1N2KA 4LRDA 4ZG7A 1E3CP 2GSNA 3IGYB 1KHLA 4FDJA 1URAA 4B56A 4LQYA 1O98A 1ELZA 4CYSA 2W8SA 2GSOA 2W5TA 1KHJA 3NKQA 3M8ZA 1HQAA 4UPLA 5L0KA 1Y6VA 2VQRA 3BDFA 4MY4A 3OT9A 5EGEA 3DPCA 3UNYA 5IJSA 4LRCA 1EW9A 5DLVA 1N2LA 3TWZA 5DLTA 5L0EA 5L0BA 3WAXA 5DLWA 4ZG9A 1ANIA 3CMRA 1URBA 3TG0A 3BDGA 1KH7A 5GRRA 4TN0A 3MK1A 3NKPA 1KH5A 3DYCA 5LQQA 1E1ZP 5HRTA 3UN5A 3WBHA 2RH6A 1SHNA 1AJAA 3KD8A 5TJ3A 1HJKA 1ELYA 1ALKA 1P49A 3UO0A 4CYRA 1ZEBA 3NKNA 3WAYA 1ZEDA 4GTZA 2XRGA 4UOPA 1AJBA 1EQJA 1Y7AA 4ZGAA 3M8WA 1AJDA 5LRNA 3M7VA 4LR2A 5K4PA 5KXAA 4KM4A 4MIVA 2GSUA 1ANJA 5EGHA 1KHKA 4LRFA 3BDGB 1K7HA 3NKMA 4KJDA 2XR9A 1EJJA 2W5RA 4ZG6A 5LRMA 4NWJA 1KHNA 3TX0A 1HDHA 3IGZB 5GOVA 4LR8A 1EW2A 4GTXA 5INHA 4KAYA 3WAVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GTY A;  1ED8 A;  1KH9 A;  1ALJ A;  3T02 A;  3A52 A;  1FSU A;  3BDH A;  3NKO A;  1AJC A;  2QZU A;  4N7T A;  1O99 A;  4UPK A;  4CXU A;  4LR9 A;  2W5X A;  4LR7 A;  1EW8 A;  2X98 A;  3Q3Q A;  1ALH A;  4UOO A;  2G9Y A;  4CXK A;  3UN3 A;  4FDI A;  4QAX A;  2ZKT A;  1AUK A;  1SHQ A;  1ELX A;  2IUC A;  4KAV A;  4CXS A;  3UN2 A;  4LRE A;  5LIA A;  3T01 A;  3E2D A;  3SZZ A;  1ALI A;  5C66 A;  2IFY A;  1KH4 A;  3MK0 A;  1ED9 A;  4LRB A;  2GLQ A;  4UOR A;  1ZEF A;  1E33 P;  2W5Q A;  2D1G A;  3B5Q A;  3T00 A;  3WAW A;  4UPH A;  1E2S P;  4GTW A;  3SZY A;  5IJQ A;  3ED4 A;  2ANH A;  4LRA A;  4YR1 A;  2W5S A;  1EI6 A;  1B8J A;  4KJG A;  3MK2 A;  5AJ9 A;  2W8D A;  3LXQ A;  3NKR A;  4UPI A;  3NVL A;  3M8Y A;  4MHX A;  2IUC B;  2W5V A;  2W5W A;  3IDD A;  2GA3 A;  4NWX A;  1N2K A;  4LRD A;  4ZG7 A;  1E3C P;  2GSN A;  3IGY B;  1KHL A;  4FDJ A;  1URA A;  4B56 A;  4LQY A;  1O98 A;  1ELZ A;  4CYS A;  2W8S A;  2GSO A;  2W5T A;  1KHJ A;  3NKQ A;  3M8Z A;  1HQA A;  4UPL A;  5L0K A;  1Y6V A;  2VQR A;  3BDF A;  4MY4 A;  3OT9 A;  5EGE A;  3DPC A;  3UNY A;  5IJS A;  4LRC A;  1EW9 A;  5DLV A;  1N2L A;  3TWZ A;  5DLT A;  5L0E A;  5L0B A;  3WAX A;  5DLW A;  4ZG9 A;  1ANI A;  3CMR A;  1URB A;  3TG0 A;  3BDG A;  1KH7 A;  5GRR A;  4TN0 A;  3MK1 A;  3NKP A;  1KH5 A;  3DYC A;  5LQQ A;  1E1Z P;  5HRT A;  3UN5 A;  3WBH A;  2RH6 A;  1SHN A;  1AJA A;  3KD8 A;  5TJ3 A;  1HJK A;  1ELY A;  1ALK A;  1P49 A;  3UO0 A;  4CYR A;  1ZEB A;  3NKN A;  3WAY A;  1ZED A;  4GTZ A;  2XRG A;  4UOP A;  1AJB A;  1EQJ A;  1Y7A A;  4ZGA A;  3M8W A;  1AJD A;  5LRN A;  3M7V A;  4LR2 A;  5K4P A;  5KXA A;  4KM4 A;  4MIV A;  2GSU A;  1ANJ A;  5EGH A;  1KHK A;  4LRF A;  3BDG B;  1K7H A;  3NKM A;  4KJD A;  2XR9 A;  1EJJ A;  2W5R A;  4ZG6 A;  5LRM A;  4NWJ A;  1KHN A;  3TX0 A;  1HDH A;  3IGZ B;  5GOV A;  4LR8 A;  1EW2 A;  4GTX A;  5INH A;  4KAY A;  3WAV A; 
#chains in the Genus database with same CATH topology
 4GTY A;  1ED8 A;  1KH9 A;  1ALJ A;  3T02 A;  3A52 A;  1FSU A;  3BDH A;  3NKO A;  1AJC A;  2QZU A;  4N7T A;  1O99 A;  4UPK A;  4CXU A;  4LR9 A;  2W5X A;  4LR7 A;  1EW8 A;  2X98 A;  3Q3Q A;  1ALH A;  4UOO A;  2G9Y A;  4CXK A;  3UN3 A;  4FDI A;  4QAX A;  2ZKT A;  1AUK A;  1SHQ A;  1ELX A;  2IUC A;  4KAV A;  4CXS A;  3UN2 A;  4LRE A;  5LIA A;  3T01 A;  3E2D A;  3SZZ A;  1ALI A;  5C66 A;  2IFY A;  1KH4 A;  3MK0 A;  1ED9 A;  4LRB A;  2GLQ A;  4UOR A;  1ZEF A;  1E33 P;  2W5Q A;  2D1G A;  3B5Q A;  3T00 A;  3WAW A;  4UPH A;  1E2S P;  4GTW A;  3SZY A;  5IJQ A;  3ED4 A;  2ANH A;  4LRA A;  4YR1 A;  2W5S A;  1EI6 A;  1B8J A;  4KJG A;  3MK2 A;  5AJ9 A;  2W8D A;  3LXQ A;  3NKR A;  4UPI A;  3NVL A;  3M8Y A;  4MHX A;  2IUC B;  2W5V A;  2W5W A;  3IDD A;  2GA3 A;  4NWX A;  1N2K A;  4LRD A;  4ZG7 A;  1E3C P;  2GSN A;  3IGY B;  1KHL A;  4FDJ A;  1URA A;  4B56 A;  4LQY A;  1O98 A;  1ELZ A;  4CYS A;  2W8S A;  2GSO A;  2W5T A;  1KHJ A;  3NKQ A;  3M8Z A;  1HQA A;  4UPL A;  5L0K A;  1Y6V A;  2VQR A;  3BDF A;  4MY4 A;  3OT9 A;  5EGE A;  3DPC A;  3UNY A;  5IJS A;  4LRC A;  1EW9 A;  5DLV A;  1N2L A;  3TWZ A;  5DLT A;  5L0E A;  5L0B A;  3WAX A;  5DLW A;  4ZG9 A;  1ANI A;  3CMR A;  1URB A;  3TG0 A;  3BDG A;  1KH7 A;  5GRR A;  4TN0 A;  3MK1 A;  3NKP A;  1KH5 A;  3DYC A;  5LQQ A;  1E1Z P;  5HRT A;  3UN5 A;  3WBH A;  2RH6 A;  1SHN A;  1AJA A;  3KD8 A;  5TJ3 A;  1HJK A;  1ELY A;  1ALK A;  1P49 A;  3UO0 A;  4CYR A;  1ZEB A;  3NKN A;  3WAY A;  1ZED A;  4GTZ A;  2XRG A;  4UOP A;  1AJB A;  1EQJ A;  1Y7A A;  4ZGA A;  3M8W A;  1AJD A;  5LRN A;  3M7V A;  4LR2 A;  5K4P A;  5KXA A;  4KM4 A;  4MIV A;  2GSU A;  1ANJ A;  5EGH A;  1KHK A;  4LRF A;  3BDG B;  1K7H A;  3NKM A;  4KJD A;  2XR9 A;  1EJJ A;  2W5R A;  4ZG6 A;  5LRM A;  4NWJ A;  1KHN A;  3TX0 A;  1HDH A;  3IGZ B;  5GOV A;  4LR8 A;  1EW2 A;  4GTX A;  5INH A;  4KAY A;  3WAV A; 
#chains in the Genus database with same CATH homology
 4GTY A;  1ED8 A;  1KH9 A;  1ALJ A;  3T02 A;  3A52 A;  1FSU A;  3BDH A;  3NKO A;  1AJC A;  2QZU A;  4N7T A;  1O99 A;  4UPK A;  4CXU A;  4LR9 A;  2W5X A;  4LR7 A;  1EW8 A;  2X98 A;  3Q3Q A;  1ALH A;  4UOO A;  2G9Y A;  4CXK A;  3UN3 A;  4FDI A;  4QAX A;  2ZKT A;  1AUK A;  1SHQ A;  1ELX A;  2IUC A;  4KAV A;  4CXS A;  3UN2 A;  4LRE A;  5LIA A;  3T01 A;  3E2D A;  3SZZ A;  1ALI A;  5C66 A;  2IFY A;  1KH4 A;  3MK0 A;  1ED9 A;  4LRB A;  2GLQ A;  4UOR A;  1ZEF A;  1E33 P;  2W5Q A;  2D1G A;  3B5Q A;  3T00 A;  3WAW A;  4UPH A;  1E2S P;  4GTW A;  3SZY A;  5IJQ A;  3ED4 A;  2ANH A;  4LRA A;  4YR1 A;  2W5S A;  1EI6 A;  1B8J A;  4KJG A;  3MK2 A;  5AJ9 A;  2W8D A;  3LXQ A;  3NKR A;  4UPI A;  3NVL A;  3M8Y A;  4MHX A;  2IUC B;  2W5V A;  2W5W A;  3IDD A;  2GA3 A;  4NWX A;  1N2K A;  4LRD A;  4ZG7 A;  1E3C P;  2GSN A;  3IGY B;  1KHL A;  4FDJ A;  1URA A;  4B56 A;  4LQY A;  1O98 A;  1ELZ A;  4CYS A;  2W8S A;  2GSO A;  2W5T A;  1KHJ A;  3NKQ A;  3M8Z A;  1HQA A;  4UPL A;  5L0K A;  1Y6V A;  2VQR A;  3BDF A;  4MY4 A;  3OT9 A;  5EGE A;  3DPC A;  3UNY A;  5IJS A;  4LRC A;  1EW9 A;  5DLV A;  1N2L A;  3TWZ A;  5DLT A;  5L0E A;  5L0B A;  3WAX A;  5DLW A;  4ZG9 A;  1ANI A;  3CMR A;  1URB A;  3TG0 A;  3BDG A;  1KH7 A;  5GRR A;  4TN0 A;  3MK1 A;  3NKP A;  1KH5 A;  3DYC A;  5LQQ A;  1E1Z P;  5HRT A;  3UN5 A;  3WBH A;  2RH6 A;  1SHN A;  1AJA A;  3KD8 A;  5TJ3 A;  1HJK A;  1ELY A;  1ALK A;  1P49 A;  3UO0 A;  4CYR A;  1ZEB A;  3NKN A;  3WAY A;  1ZED A;  4GTZ A;  2XRG A;  4UOP A;  1AJB A;  1EQJ A;  1Y7A A;  4ZGA A;  3M8W A;  1AJD A;  5LRN A;  3M7V A;  4LR2 A;  5K4P A;  5KXA A;  4KM4 A;  4MIV A;  2GSU A;  1ANJ A;  5EGH A;  1KHK A;  4LRF A;  3BDG B;  1K7H A;  3NKM A;  4KJD A;  2XR9 A;  1EJJ A;  2W5R A;  4ZG6 A;  5LRM A;  4NWJ A;  1KHN A;  3TX0 A;  1HDH A;  3IGZ B;  5GOV A;  4LR8 A;  1EW2 A;  4GTX A;  5INH A;  4KAY A;  3WAV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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