4NWXA

Crystal structure of phosphoglycerate mutase from staphylococcus aureus in 2-phosphoglyceric acid bound form
Total Genus 194
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
194
Knots found
sequence length
503
structure length
503
Chain Sequence
KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
publication title Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism
pubmed doi rcsb
source organism Staphylococcus aureus subsp. aureus
total genus 194
structure length 503
sequence length 503
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2013-12-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4nwxA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 4nwxA02
4GTZA 5INHA 4YR1A 4GTWA 3UN5A 2GA3A 3NKQA 1E33P 4LR8A 1ZEDA 5LRNA 3IGZB 2IUCA 1ELXA 3WBHA 1E1ZP 3UN2A 4NWXA 5LQQA 3E2DA 3TWZA 1ALIA 2IFYA 3UN3A 4LRFA 1P49A 2W5TA 1ELYA 1B8JA 1KHJA 1KHNA 5LRMA 1HJKA 4LRBA 3WAXA 3A52A 5KXAA 1ED8A 2W5VA 3WAWA 4KAYA 1HDHA 3CMRA 2W5XA 1AJCA 1N2KA 2W8SA 2W5RA 4GTXA 1KH5A 4N7TA 4LR7A 1ANIA 1EW8A 3ED4A 4KAVA 3T01A 4TN0A 1SHNA 3MK2A 2G9YA 3NKRA 2W5WA 1SHQA 4UPLA 3OT9A 2ANHA 2W5QA 3LXQA 4B56A 3WAYA 1ZEBA 3NKMA 3MK0A 5GRRA 3B5QA 4NWJA 3KD8A 1ZEFA 4LRDA 4QAXA 1AJDA 1K7HA 2QZUA 4FDJA 2GLQA 4UORA 5DLWA 5DLTA 5GOVA 3T02A 1ANJA 2X98A 4CXKA 1EI6A 1N2LA 2VQRA 3T00A 2IUCB 4LR2A 4UPHA 4UPIA 3UNYA 3WAVA 4LR9A 4ZG9A 3BDFA 1O98A 1HQAA 2XRGA 1KH4A 3BDGB 3M8YA 4KJGA 4MHXA 5EGHA 3TX0A 1AUKA 2GSUA 1ED9A 2XR9A 4LREA 4ZGAA 4UPKA 1EW9A 3UO0A 3DPCA 4LQYA 2W8DA 4CYRA 4MIVA 1ELZA 3SZZA 3M8WA 5L0KA 5LIAA 3TG0A 4LRAA 3NVLA 5L0EA 3MK1A 1Y6VA 1KHLA 3NKNA 4MY4A 5HRTA 1FSUA 5DLVA 5C66A 1EQJA 1KH9A 3NKOA 1EW2A 5IJSA 1AJBA 3IGYB 2ZKTA 1KHKA 2D1GA 2RH6A 4ZG7A 5IJQA 1ALJA 1AJAA 3BDHA 1URBA 3M8ZA 1O99A 1URAA 3BDGA 2GSOA 4KJDA 1KH7A 5K4PA 1ALHA 4FDIA 4CXUA 3M7VA 1Y7AA 4CXSA 2W5SA 3SZYA 3IDDA 3DYCA 1ALKA 1E2SP 2GSNA 1E3CP 5AJ9A 4CYSA 4GTYA 4KM4A 5EGEA 4UOPA 5TJ3A 4UOOA 5L0BA 1EJJA 3NKPA 4LRCA 4ZG6A 3Q3QA
chains in the Genus database with same CATH superfamily
4GTZA 5INHA 4YR1A 4GTWA 3UN5A 2GA3A 3NKQA 1E33P 4LR8A 1ZEDA 5LRNA 3IGZB 2IUCA 1ELXA 3WBHA 1E1ZP 3UN2A 4NWXA 5LQQA 3E2DA 3TWZA 1ALIA 2IFYA 3UN3A 4LRFA 1P49A 2W5TA 1ELYA 1B8JA 1KHJA 1KHNA 5LRMA 1HJKA 4LRBA 3WAXA 3A52A 5KXAA 1ED8A 2W5VA 3WAWA 4KAYA 1HDHA 3CMRA 2W5XA 1AJCA 1N2KA 2W8SA 2W5RA 4GTXA 1KH5A 4N7TA 4LR7A 1ANIA 1EW8A 3ED4A 4KAVA 3T01A 4TN0A 1SHNA 3MK2A 2G9YA 3NKRA 2W5WA 1SHQA 4UPLA 3OT9A 2ANHA 2W5QA 3LXQA 4B56A 3WAYA 1ZEBA 3NKMA 3MK0A 5GRRA 3B5QA 4NWJA 3KD8A 1ZEFA 4LRDA 4QAXA 1AJDA 1K7HA 2QZUA 4FDJA 2GLQA 4UORA 5DLWA 5DLTA 5GOVA 3T02A 1ANJA 2X98A 4CXKA 1EI6A 1N2LA 2VQRA 3T00A 2IUCB 4LR2A 4UPHA 4UPIA 3UNYA 3WAVA 4LR9A 4ZG9A 3BDFA 1O98A 1HQAA 2XRGA 1KH4A 3BDGB 3M8YA 4KJGA 4MHXA 5EGHA 3TX0A 1AUKA 2GSUA 1ED9A 2XR9A 4LREA 4ZGAA 4UPKA 1EW9A 3UO0A 3DPCA 4LQYA 2W8DA 4CYRA 4MIVA 1ELZA 3SZZA 3M8WA 5L0KA 5LIAA 3TG0A 4LRAA 3NVLA 5L0EA 3MK1A 1Y6VA 1KHLA 3NKNA 4MY4A 5HRTA 1FSUA 5DLVA 5C66A 1EQJA 1KH9A 3NKOA 1EW2A 5IJSA 1AJBA 3IGYB 2ZKTA 1KHKA 2D1GA 2RH6A 4ZG7A 5IJQA 1ALJA 1AJAA 3BDHA 1URBA 3M8ZA 1O99A 1URAA 3BDGA 2GSOA 4KJDA 1KH7A 5K4PA 1ALHA 4FDIA 4CXUA 3M7VA 1Y7AA 4CXSA 2W5SA 3SZYA 3IDDA 3DYCA 1ALKA 1E2SP 2GSNA 1E3CP 5AJ9A 4CYSA 4GTYA 4KM4A 5EGEA 4UOPA 5TJ3A 4UOOA 5L0BA 1EJJA 3NKPA 4LRCA 4ZG6A 3Q3QA
chains in the Genus database with same CATH topology
4GTZA 5INHA 4YR1A 4GTWA 3UN5A 2GA3A 3NKQA 1E33P 4LR8A 1ZEDA 5LRNA 3IGZB 2IUCA 1ELXA 3WBHA 1E1ZP 3UN2A 4NWXA 5LQQA 3E2DA 3TWZA 1ALIA 2IFYA 3UN3A 4LRFA 1P49A 2W5TA 1ELYA 1B8JA 1KHJA 1KHNA 5LRMA 1HJKA 4LRBA 3WAXA 3A52A 5KXAA 1ED8A 2W5VA 3WAWA 4KAYA 1HDHA 3CMRA 2W5XA 1AJCA 1N2KA 2W8SA 2W5RA 4GTXA 1KH5A 4N7TA 4LR7A 1ANIA 1EW8A 3ED4A 4KAVA 3T01A 4TN0A 1SHNA 3MK2A 2G9YA 3NKRA 2W5WA 1SHQA 4UPLA 3OT9A 2ANHA 2W5QA 3LXQA 4B56A 3WAYA 1ZEBA 3NKMA 3MK0A 5GRRA 3B5QA 4NWJA 3KD8A 1ZEFA 4LRDA 4QAXA 1AJDA 1K7HA 2QZUA 4FDJA 2GLQA 4UORA 5DLWA 5DLTA 5GOVA 3T02A 1ANJA 2X98A 4CXKA 1EI6A 1N2LA 2VQRA 3T00A 2IUCB 4LR2A 4UPHA 4UPIA 3UNYA 3WAVA 4LR9A 4ZG9A 3BDFA 1O98A 1HQAA 2XRGA 1KH4A 3BDGB 3M8YA 4KJGA 4MHXA 5EGHA 3TX0A 1AUKA 2GSUA 1ED9A 2XR9A 4LREA 4ZGAA 4UPKA 1EW9A 3UO0A 3DPCA 4LQYA 2W8DA 4CYRA 4MIVA 1ELZA 3SZZA 3M8WA 5L0KA 5LIAA 3TG0A 4LRAA 3NVLA 5L0EA 3MK1A 1Y6VA 1KHLA 3NKNA 4MY4A 5HRTA 1FSUA 5DLVA 5C66A 1EQJA 1KH9A 3NKOA 1EW2A 5IJSA 1AJBA 3IGYB 2ZKTA 1KHKA 2D1GA 2RH6A 4ZG7A 5IJQA 1ALJA 1AJAA 3BDHA 1URBA 3M8ZA 1O99A 1URAA 3BDGA 2GSOA 4KJDA 1KH7A 5K4PA 1ALHA 4FDIA 4CXUA 3M7VA 1Y7AA 4CXSA 2W5SA 3SZYA 3IDDA 3DYCA 1ALKA 1E2SP 2GSNA 1E3CP 5AJ9A 4CYSA 4GTYA 4KM4A 5EGEA 4UOPA 5TJ3A 4UOOA 5L0BA 1EJJA 3NKPA 4LRCA 4ZG6A 3Q3QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GTZ A;  5INH A;  4YR1 A;  4GTW A;  3UN5 A;  2GA3 A;  3NKQ A;  1E33 P;  4LR8 A;  1ZED A;  5LRN A;  3IGZ B;  2IUC A;  1ELX A;  3WBH A;  1E1Z P;  3UN2 A;  4NWX A;  5LQQ A;  3E2D A;  3TWZ A;  1ALI A;  2IFY A;  3UN3 A;  4LRF A;  1P49 A;  2W5T A;  1ELY A;  1B8J A;  1KHJ A;  1KHN A;  5LRM A;  1HJK A;  4LRB A;  3WAX A;  3A52 A;  5KXA A;  1ED8 A;  2W5V A;  3WAW A;  4KAY A;  1HDH A;  3CMR A;  2W5X A;  1AJC A;  1N2K A;  2W8S A;  2W5R A;  4GTX A;  1KH5 A;  4N7T A;  4LR7 A;  1ANI A;  1EW8 A;  3ED4 A;  4KAV A;  3T01 A;  4TN0 A;  1SHN A;  3MK2 A;  2G9Y A;  3NKR A;  2W5W A;  1SHQ A;  4UPL A;  3OT9 A;  2ANH A;  2W5Q A;  3LXQ A;  4B56 A;  3WAY A;  1ZEB A;  3NKM A;  3MK0 A;  5GRR A;  3B5Q A;  4NWJ A;  3KD8 A;  1ZEF A;  4LRD A;  4QAX A;  1AJD A;  1K7H A;  2QZU A;  4FDJ A;  2GLQ A;  4UOR A;  5DLW A;  5DLT A;  5GOV A;  3T02 A;  1ANJ A;  2X98 A;  4CXK A;  1EI6 A;  1N2L A;  2VQR A;  3T00 A;  2IUC B;  4LR2 A;  4UPH A;  4UPI A;  3UNY A;  3WAV A;  4LR9 A;  4ZG9 A;  3BDF A;  1O98 A;  1HQA A;  2XRG A;  1KH4 A;  3BDG B;  3M8Y A;  4KJG A;  4MHX A;  5EGH A;  3TX0 A;  1AUK A;  2GSU A;  1ED9 A;  2XR9 A;  4LRE A;  4ZGA A;  4UPK A;  1EW9 A;  3UO0 A;  3DPC A;  4LQY A;  2W8D A;  4CYR A;  4MIV A;  1ELZ A;  3SZZ A;  3M8W A;  5L0K A;  5LIA A;  3TG0 A;  4LRA A;  3NVL A;  5L0E A;  3MK1 A;  1Y6V A;  1KHL A;  3NKN A;  4MY4 A;  5HRT A;  1FSU A;  5DLV A;  5C66 A;  1EQJ A;  1KH9 A;  3NKO A;  1EW2 A;  5IJS A;  1AJB A;  3IGY B;  2ZKT A;  1KHK A;  2D1G A;  2RH6 A;  4ZG7 A;  5IJQ A;  1ALJ A;  1AJA A;  3BDH A;  1URB A;  3M8Z A;  1O99 A;  1URA A;  3BDG A;  2GSO A;  4KJD A;  1KH7 A;  5K4P A;  1ALH A;  4FDI A;  4CXU A;  3M7V A;  1Y7A A;  4CXS A;  2W5S A;  3SZY A;  3IDD A;  3DYC A;  1ALK A;  1E2S P;  2GSN A;  1E3C P;  5AJ9 A;  4CYS A;  4GTY A;  4KM4 A;  5EGE A;  4UOP A;  5TJ3 A;  4UOO A;  5L0B A;  1EJJ A;  3NKP A;  4LRC A;  4ZG6 A;  3Q3Q A; 
#chains in the Genus database with same CATH topology
 4GTZ A;  5INH A;  4YR1 A;  4GTW A;  3UN5 A;  2GA3 A;  3NKQ A;  1E33 P;  4LR8 A;  1ZED A;  5LRN A;  3IGZ B;  2IUC A;  1ELX A;  3WBH A;  1E1Z P;  3UN2 A;  4NWX A;  5LQQ A;  3E2D A;  3TWZ A;  1ALI A;  2IFY A;  3UN3 A;  4LRF A;  1P49 A;  2W5T A;  1ELY A;  1B8J A;  1KHJ A;  1KHN A;  5LRM A;  1HJK A;  4LRB A;  3WAX A;  3A52 A;  5KXA A;  1ED8 A;  2W5V A;  3WAW A;  4KAY A;  1HDH A;  3CMR A;  2W5X A;  1AJC A;  1N2K A;  2W8S A;  2W5R A;  4GTX A;  1KH5 A;  4N7T A;  4LR7 A;  1ANI A;  1EW8 A;  3ED4 A;  4KAV A;  3T01 A;  4TN0 A;  1SHN A;  3MK2 A;  2G9Y A;  3NKR A;  2W5W A;  1SHQ A;  4UPL A;  3OT9 A;  2ANH A;  2W5Q A;  3LXQ A;  4B56 A;  3WAY A;  1ZEB A;  3NKM A;  3MK0 A;  5GRR A;  3B5Q A;  4NWJ A;  3KD8 A;  1ZEF A;  4LRD A;  4QAX A;  1AJD A;  1K7H A;  2QZU A;  4FDJ A;  2GLQ A;  4UOR A;  5DLW A;  5DLT A;  5GOV A;  3T02 A;  1ANJ A;  2X98 A;  4CXK A;  1EI6 A;  1N2L A;  2VQR A;  3T00 A;  2IUC B;  4LR2 A;  4UPH A;  4UPI A;  3UNY A;  3WAV A;  4LR9 A;  4ZG9 A;  3BDF A;  1O98 A;  1HQA A;  2XRG A;  1KH4 A;  3BDG B;  3M8Y A;  4KJG A;  4MHX A;  5EGH A;  3TX0 A;  1AUK A;  2GSU A;  1ED9 A;  2XR9 A;  4LRE A;  4ZGA A;  4UPK A;  1EW9 A;  3UO0 A;  3DPC A;  4LQY A;  2W8D A;  4CYR A;  4MIV A;  1ELZ A;  3SZZ A;  3M8W A;  5L0K A;  5LIA A;  3TG0 A;  4LRA A;  3NVL A;  5L0E A;  3MK1 A;  1Y6V A;  1KHL A;  3NKN A;  4MY4 A;  5HRT A;  1FSU A;  5DLV A;  5C66 A;  1EQJ A;  1KH9 A;  3NKO A;  1EW2 A;  5IJS A;  1AJB A;  3IGY B;  2ZKT A;  1KHK A;  2D1G A;  2RH6 A;  4ZG7 A;  5IJQ A;  1ALJ A;  1AJA A;  3BDH A;  1URB A;  3M8Z A;  1O99 A;  1URA A;  3BDG A;  2GSO A;  4KJD A;  1KH7 A;  5K4P A;  1ALH A;  4FDI A;  4CXU A;  3M7V A;  1Y7A A;  4CXS A;  2W5S A;  3SZY A;  3IDD A;  3DYC A;  1ALK A;  1E2S P;  2GSN A;  1E3C P;  5AJ9 A;  4CYS A;  4GTY A;  4KM4 A;  5EGE A;  4UOP A;  5TJ3 A;  4UOO A;  5L0B A;  1EJJ A;  3NKP A;  4LRC A;  4ZG6 A;  3Q3Q A; 
#chains in the Genus database with same CATH homology
 4GTZ A;  5INH A;  4YR1 A;  4GTW A;  3UN5 A;  2GA3 A;  3NKQ A;  1E33 P;  4LR8 A;  1ZED A;  5LRN A;  3IGZ B;  2IUC A;  1ELX A;  3WBH A;  1E1Z P;  3UN2 A;  4NWX A;  5LQQ A;  3E2D A;  3TWZ A;  1ALI A;  2IFY A;  3UN3 A;  4LRF A;  1P49 A;  2W5T A;  1ELY A;  1B8J A;  1KHJ A;  1KHN A;  5LRM A;  1HJK A;  4LRB A;  3WAX A;  3A52 A;  5KXA A;  1ED8 A;  2W5V A;  3WAW A;  4KAY A;  1HDH A;  3CMR A;  2W5X A;  1AJC A;  1N2K A;  2W8S A;  2W5R A;  4GTX A;  1KH5 A;  4N7T A;  4LR7 A;  1ANI A;  1EW8 A;  3ED4 A;  4KAV A;  3T01 A;  4TN0 A;  1SHN A;  3MK2 A;  2G9Y A;  3NKR A;  2W5W A;  1SHQ A;  4UPL A;  3OT9 A;  2ANH A;  2W5Q A;  3LXQ A;  4B56 A;  3WAY A;  1ZEB A;  3NKM A;  3MK0 A;  5GRR A;  3B5Q A;  4NWJ A;  3KD8 A;  1ZEF A;  4LRD A;  4QAX A;  1AJD A;  1K7H A;  2QZU A;  4FDJ A;  2GLQ A;  4UOR A;  5DLW A;  5DLT A;  5GOV A;  3T02 A;  1ANJ A;  2X98 A;  4CXK A;  1EI6 A;  1N2L A;  2VQR A;  3T00 A;  2IUC B;  4LR2 A;  4UPH A;  4UPI A;  3UNY A;  3WAV A;  4LR9 A;  4ZG9 A;  3BDF A;  1O98 A;  1HQA A;  2XRG A;  1KH4 A;  3BDG B;  3M8Y A;  4KJG A;  4MHX A;  5EGH A;  3TX0 A;  1AUK A;  2GSU A;  1ED9 A;  2XR9 A;  4LRE A;  4ZGA A;  4UPK A;  1EW9 A;  3UO0 A;  3DPC A;  4LQY A;  2W8D A;  4CYR A;  4MIV A;  1ELZ A;  3SZZ A;  3M8W A;  5L0K A;  5LIA A;  3TG0 A;  4LRA A;  3NVL A;  5L0E A;  3MK1 A;  1Y6V A;  1KHL A;  3NKN A;  4MY4 A;  5HRT A;  1FSU A;  5DLV A;  5C66 A;  1EQJ A;  1KH9 A;  3NKO A;  1EW2 A;  5IJS A;  1AJB A;  3IGY B;  2ZKT A;  1KHK A;  2D1G A;  2RH6 A;  4ZG7 A;  5IJQ A;  1ALJ A;  1AJA A;  3BDH A;  1URB A;  3M8Z A;  1O99 A;  1URA A;  3BDG A;  2GSO A;  4KJD A;  1KH7 A;  5K4P A;  1ALH A;  4FDI A;  4CXU A;  3M7V A;  1Y7A A;  4CXS A;  2W5S A;  3SZY A;  3IDD A;  3DYC A;  1ALK A;  1E2S P;  2GSN A;  1E3C P;  5AJ9 A;  4CYS A;  4GTY A;  4KM4 A;  5EGE A;  4UOP A;  5TJ3 A;  4UOO A;  5L0B A;  1EJJ A;  3NKP A;  4LRC A;  4ZG6 A;  3Q3Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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