5C66A

E. coli alkaline phosphatase in complex with tungstate
Total Genus 161
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
161
Knots found
sequence length
441
structure length
441
Chain Sequence
b'NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Alkaline phosphatase
publication title Tungstate as a Transition State Analog for Catalysis by Alkaline Phosphatase.
pubmed doi rcsb
source organism Escherichia coli (strain k12)
molecule tags Hydrolase
total genus 161
structure length 441
sequence length 441
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2015-06-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5c66A00
4CXUA 4UORA 2W5SA 1SHNA 3NKNA 5DLWA 5KXAA 1KHNA 1B8JA 5AJ9A 1AJDA 3NKMA 5IJQA 1KH5A 4MHXA 3T00A 3MK1A 4UPIA 1KHJA 1E33P 3WAVA 3UN2A 5DLTA 4FDJA 3WBHA 3BDHA 3TWZA 4YR1A 3E2DA 5LQQA 1ANJA 2VQRA 1ELXA 1ED8A 2W5TA 3BDGB 3Q3QA 1EW8A 3KD8A 3M8YA 4LR7A 1AJBA 3NKRA 3UNYA 4CYSA 3M8ZA 2W5QA 1ZEFA 2X98A 4UPHA 4GTXA 4LREA 1EW9A 2XR9A 1E3CP 4LRAA 3UN3A 1SHQA 2W5RA 1EW2A 2RH6A 1N2KA 3MK0A 4FDIA 1ELYA 2IFYA 5LRMA 1AJAA 4GTZA 1AJCA 1URBA 3BDGA 1KH9A 2GLQA 5L0KA 3NVLA 4MY4A 3T01A 3UN5A 1P49A 3TX0A 1ALHA 4KAVA 4KM4A 1K7HA 3WAXA 4LQYA 1KH7A 3M8WA 4KJDA 1Y7AA 4ZGAA 3A52A 4GTYA 1E2SP 4KAYA 5EGEA 1AUKA 4CYRA 1ELZA 2ANHA 3T02A 4TN0A 5LRNA 4UOPA 4N7TA 1KH4A 1HJKA 3NKOA 4B56A 3TG0A 4LR8A 1ED9A 5L0BA 1ZEBA 2W5XA 4CXKA 1ALJA 5LIAA 4LR2A 1N2LA 5INHA 1ANIA 3UO0A 3IGZB 1HDHA 3ED4A 1EI6A 2ZKTA 1HQAA 4ZG6A 5IJSA 5GOVA 2W5WA 3WAWA 3IGYB 2GSUA 4LRCA 3DPCA 5C66A 1KHKA 3LXQA 4MIVA 3IDDA 4UOOA 2QZUA 1O98A 4UPKA 1ALKA 3BDFA 3B5QA 2GSOA 4NWXA 3M7VA 5K4PA 1FSUA 3MK2A 1ALIA 2IUCB 3DYCA 4KJGA 2GSNA 4LR9A 1EJJA 3OT9A 4UPLA 2W8SA 1ZEDA 2W5VA 1O99A 2G9YA 3CMRA 5TJ3A 3WAYA 4QAXA 1URAA 1E1ZP 1EQJA 1KHLA 3NKPA 4LRDA 5EGHA 5GRRA 1Y6VA 4LRBA 4LRFA 2D1GA 4NWJA 2IUCA 3SZZA 4ZG7A 2GA3A 4CXSA 3NKQA 5L0EA 2XRGA 4ZG9A 5DLVA 4GTWA 5HRTA 2W8DA 3SZYA
chains in the Genus database with same CATH superfamily
4CXUA 4UORA 2W5SA 1SHNA 3NKNA 5DLWA 5KXAA 1KHNA 1B8JA 5AJ9A 1AJDA 3NKMA 5IJQA 1KH5A 4MHXA 3T00A 3MK1A 4UPIA 1KHJA 1E33P 3WAVA 3UN2A 5DLTA 4FDJA 3WBHA 3BDHA 3TWZA 4YR1A 3E2DA 5LQQA 1ANJA 2VQRA 1ELXA 1ED8A 2W5TA 3BDGB 3Q3QA 1EW8A 3KD8A 3M8YA 4LR7A 1AJBA 3NKRA 3UNYA 4CYSA 3M8ZA 2W5QA 1ZEFA 2X98A 4UPHA 4GTXA 4LREA 1EW9A 2XR9A 1E3CP 4LRAA 3UN3A 1SHQA 2W5RA 1EW2A 2RH6A 1N2KA 3MK0A 4FDIA 1ELYA 2IFYA 5LRMA 1AJAA 4GTZA 1AJCA 1URBA 3BDGA 1KH9A 2GLQA 5L0KA 3NVLA 4MY4A 3T01A 3UN5A 1P49A 3TX0A 1ALHA 4KAVA 4KM4A 1K7HA 3WAXA 4LQYA 1KH7A 3M8WA 4KJDA 1Y7AA 4ZGAA 3A52A 4GTYA 1E2SP 4KAYA 5EGEA 1AUKA 4CYRA 1ELZA 2ANHA 3T02A 4TN0A 5LRNA 4UOPA 4N7TA 1KH4A 1HJKA 3NKOA 4B56A 3TG0A 4LR8A 1ED9A 5L0BA 1ZEBA 2W5XA 4CXKA 1ALJA 5LIAA 4LR2A 1N2LA 5INHA 1ANIA 3UO0A 3IGZB 1HDHA 3ED4A 1EI6A 2ZKTA 1HQAA 4ZG6A 5IJSA 5GOVA 2W5WA 3WAWA 3IGYB 2GSUA 4LRCA 3DPCA 5C66A 1KHKA 3LXQA 4MIVA 3IDDA 4UOOA 2QZUA 1O98A 4UPKA 1ALKA 3BDFA 3B5QA 2GSOA 4NWXA 3M7VA 5K4PA 1FSUA 3MK2A 1ALIA 2IUCB 3DYCA 4KJGA 2GSNA 4LR9A 1EJJA 3OT9A 4UPLA 2W8SA 1ZEDA 2W5VA 1O99A 2G9YA 3CMRA 5TJ3A 3WAYA 4QAXA 1URAA 1E1ZP 1EQJA 1KHLA 3NKPA 4LRDA 5EGHA 5GRRA 1Y6VA 4LRBA 4LRFA 2D1GA 4NWJA 2IUCA 3SZZA 4ZG7A 2GA3A 4CXSA 3NKQA 5L0EA 2XRGA 4ZG9A 5DLVA 4GTWA 5HRTA 2W8DA 3SZYA
chains in the Genus database with same CATH topology
4CXUA 4UORA 2W5SA 1SHNA 3NKNA 5DLWA 5KXAA 1KHNA 1B8JA 5AJ9A 1AJDA 3NKMA 5IJQA 1KH5A 4MHXA 3T00A 3MK1A 4UPIA 1KHJA 1E33P 3WAVA 3UN2A 5DLTA 4FDJA 3WBHA 3BDHA 3TWZA 4YR1A 3E2DA 5LQQA 1ANJA 2VQRA 1ELXA 1ED8A 2W5TA 3BDGB 3Q3QA 1EW8A 3KD8A 3M8YA 4LR7A 1AJBA 3NKRA 3UNYA 4CYSA 3M8ZA 2W5QA 1ZEFA 2X98A 4UPHA 4GTXA 4LREA 1EW9A 2XR9A 1E3CP 4LRAA 3UN3A 1SHQA 2W5RA 1EW2A 2RH6A 1N2KA 3MK0A 4FDIA 1ELYA 2IFYA 5LRMA 1AJAA 4GTZA 1AJCA 1URBA 3BDGA 1KH9A 2GLQA 5L0KA 3NVLA 4MY4A 3T01A 3UN5A 1P49A 3TX0A 1ALHA 4KAVA 4KM4A 1K7HA 3WAXA 4LQYA 1KH7A 3M8WA 4KJDA 1Y7AA 4ZGAA 3A52A 4GTYA 1E2SP 4KAYA 5EGEA 1AUKA 4CYRA 1ELZA 2ANHA 3T02A 4TN0A 5LRNA 4UOPA 4N7TA 1KH4A 1HJKA 3NKOA 4B56A 3TG0A 4LR8A 1ED9A 5L0BA 1ZEBA 2W5XA 4CXKA 1ALJA 5LIAA 4LR2A 1N2LA 5INHA 1ANIA 3UO0A 3IGZB 1HDHA 3ED4A 1EI6A 2ZKTA 1HQAA 4ZG6A 5IJSA 5GOVA 2W5WA 3WAWA 3IGYB 2GSUA 4LRCA 3DPCA 5C66A 1KHKA 3LXQA 4MIVA 3IDDA 4UOOA 2QZUA 1O98A 4UPKA 1ALKA 3BDFA 3B5QA 2GSOA 4NWXA 3M7VA 5K4PA 1FSUA 3MK2A 1ALIA 2IUCB 3DYCA 4KJGA 2GSNA 4LR9A 1EJJA 3OT9A 4UPLA 2W8SA 1ZEDA 2W5VA 1O99A 2G9YA 3CMRA 5TJ3A 3WAYA 4QAXA 1URAA 1E1ZP 1EQJA 1KHLA 3NKPA 4LRDA 5EGHA 5GRRA 1Y6VA 4LRBA 4LRFA 2D1GA 4NWJA 2IUCA 3SZZA 4ZG7A 2GA3A 4CXSA 3NKQA 5L0EA 2XRGA 4ZG9A 5DLVA 4GTWA 5HRTA 2W8DA 3SZYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CXU A;  4UOR A;  2W5S A;  1SHN A;  3NKN A;  5DLW A;  5KXA A;  1KHN A;  1B8J A;  5AJ9 A;  1AJD A;  3NKM A;  5IJQ A;  1KH5 A;  4MHX A;  3T00 A;  3MK1 A;  4UPI A;  1KHJ A;  1E33 P;  3WAV A;  3UN2 A;  5DLT A;  4FDJ A;  3WBH A;  3BDH A;  3TWZ A;  4YR1 A;  3E2D A;  5LQQ A;  1ANJ A;  2VQR A;  1ELX A;  1ED8 A;  2W5T A;  3BDG B;  3Q3Q A;  1EW8 A;  3KD8 A;  3M8Y A;  4LR7 A;  1AJB A;  3NKR A;  3UNY A;  4CYS A;  3M8Z A;  2W5Q A;  1ZEF A;  2X98 A;  4UPH A;  4GTX A;  4LRE A;  1EW9 A;  2XR9 A;  1E3C P;  4LRA A;  3UN3 A;  1SHQ A;  2W5R A;  1EW2 A;  2RH6 A;  1N2K A;  3MK0 A;  4FDI A;  1ELY A;  2IFY A;  5LRM A;  1AJA A;  4GTZ A;  1AJC A;  1URB A;  3BDG A;  1KH9 A;  2GLQ A;  5L0K A;  3NVL A;  4MY4 A;  3T01 A;  3UN5 A;  1P49 A;  3TX0 A;  1ALH A;  4KAV A;  4KM4 A;  1K7H A;  3WAX A;  4LQY A;  1KH7 A;  3M8W A;  4KJD A;  1Y7A A;  4ZGA A;  3A52 A;  4GTY A;  1E2S P;  4KAY A;  5EGE A;  1AUK A;  4CYR A;  1ELZ A;  2ANH A;  3T02 A;  4TN0 A;  5LRN A;  4UOP A;  4N7T A;  1KH4 A;  1HJK A;  3NKO A;  4B56 A;  3TG0 A;  4LR8 A;  1ED9 A;  5L0B A;  1ZEB A;  2W5X A;  4CXK A;  1ALJ A;  5LIA A;  4LR2 A;  1N2L A;  5INH A;  1ANI A;  3UO0 A;  3IGZ B;  1HDH A;  3ED4 A;  1EI6 A;  2ZKT A;  1HQA A;  4ZG6 A;  5IJS A;  5GOV A;  2W5W A;  3WAW A;  3IGY B;  2GSU A;  4LRC A;  3DPC A;  5C66 A;  1KHK A;  3LXQ A;  4MIV A;  3IDD A;  4UOO A;  2QZU A;  1O98 A;  4UPK A;  1ALK A;  3BDF A;  3B5Q A;  2GSO A;  4NWX A;  3M7V A;  5K4P A;  1FSU A;  3MK2 A;  1ALI A;  2IUC B;  3DYC A;  4KJG A;  2GSN A;  4LR9 A;  1EJJ A;  3OT9 A;  4UPL A;  2W8S A;  1ZED A;  2W5V A;  1O99 A;  2G9Y A;  3CMR A;  5TJ3 A;  3WAY A;  4QAX A;  1URA A;  1E1Z P;  1EQJ A;  1KHL A;  3NKP A;  4LRD A;  5EGH A;  5GRR A;  1Y6V A;  4LRB A;  4LRF A;  2D1G A;  4NWJ A;  2IUC A;  3SZZ A;  4ZG7 A;  2GA3 A;  4CXS A;  3NKQ A;  5L0E A;  2XRG A;  4ZG9 A;  5DLV A;  4GTW A;  5HRT A;  2W8D A;  3SZY A; 
#chains in the Genus database with same CATH topology
 4CXU A;  4UOR A;  2W5S A;  1SHN A;  3NKN A;  5DLW A;  5KXA A;  1KHN A;  1B8J A;  5AJ9 A;  1AJD A;  3NKM A;  5IJQ A;  1KH5 A;  4MHX A;  3T00 A;  3MK1 A;  4UPI A;  1KHJ A;  1E33 P;  3WAV A;  3UN2 A;  5DLT A;  4FDJ A;  3WBH A;  3BDH A;  3TWZ A;  4YR1 A;  3E2D A;  5LQQ A;  1ANJ A;  2VQR A;  1ELX A;  1ED8 A;  2W5T A;  3BDG B;  3Q3Q A;  1EW8 A;  3KD8 A;  3M8Y A;  4LR7 A;  1AJB A;  3NKR A;  3UNY A;  4CYS A;  3M8Z A;  2W5Q A;  1ZEF A;  2X98 A;  4UPH A;  4GTX A;  4LRE A;  1EW9 A;  2XR9 A;  1E3C P;  4LRA A;  3UN3 A;  1SHQ A;  2W5R A;  1EW2 A;  2RH6 A;  1N2K A;  3MK0 A;  4FDI A;  1ELY A;  2IFY A;  5LRM A;  1AJA A;  4GTZ A;  1AJC A;  1URB A;  3BDG A;  1KH9 A;  2GLQ A;  5L0K A;  3NVL A;  4MY4 A;  3T01 A;  3UN5 A;  1P49 A;  3TX0 A;  1ALH A;  4KAV A;  4KM4 A;  1K7H A;  3WAX A;  4LQY A;  1KH7 A;  3M8W A;  4KJD A;  1Y7A A;  4ZGA A;  3A52 A;  4GTY A;  1E2S P;  4KAY A;  5EGE A;  1AUK A;  4CYR A;  1ELZ A;  2ANH A;  3T02 A;  4TN0 A;  5LRN A;  4UOP A;  4N7T A;  1KH4 A;  1HJK A;  3NKO A;  4B56 A;  3TG0 A;  4LR8 A;  1ED9 A;  5L0B A;  1ZEB A;  2W5X A;  4CXK A;  1ALJ A;  5LIA A;  4LR2 A;  1N2L A;  5INH A;  1ANI A;  3UO0 A;  3IGZ B;  1HDH A;  3ED4 A;  1EI6 A;  2ZKT A;  1HQA A;  4ZG6 A;  5IJS A;  5GOV A;  2W5W A;  3WAW A;  3IGY B;  2GSU A;  4LRC A;  3DPC A;  5C66 A;  1KHK A;  3LXQ A;  4MIV A;  3IDD A;  4UOO A;  2QZU A;  1O98 A;  4UPK A;  1ALK A;  3BDF A;  3B5Q A;  2GSO A;  4NWX A;  3M7V A;  5K4P A;  1FSU A;  3MK2 A;  1ALI A;  2IUC B;  3DYC A;  4KJG A;  2GSN A;  4LR9 A;  1EJJ A;  3OT9 A;  4UPL A;  2W8S A;  1ZED A;  2W5V A;  1O99 A;  2G9Y A;  3CMR A;  5TJ3 A;  3WAY A;  4QAX A;  1URA A;  1E1Z P;  1EQJ A;  1KHL A;  3NKP A;  4LRD A;  5EGH A;  5GRR A;  1Y6V A;  4LRB A;  4LRF A;  2D1G A;  4NWJ A;  2IUC A;  3SZZ A;  4ZG7 A;  2GA3 A;  4CXS A;  3NKQ A;  5L0E A;  2XRG A;  4ZG9 A;  5DLV A;  4GTW A;  5HRT A;  2W8D A;  3SZY A; 
#chains in the Genus database with same CATH homology
 4CXU A;  4UOR A;  2W5S A;  1SHN A;  3NKN A;  5DLW A;  5KXA A;  1KHN A;  1B8J A;  5AJ9 A;  1AJD A;  3NKM A;  5IJQ A;  1KH5 A;  4MHX A;  3T00 A;  3MK1 A;  4UPI A;  1KHJ A;  1E33 P;  3WAV A;  3UN2 A;  5DLT A;  4FDJ A;  3WBH A;  3BDH A;  3TWZ A;  4YR1 A;  3E2D A;  5LQQ A;  1ANJ A;  2VQR A;  1ELX A;  1ED8 A;  2W5T A;  3BDG B;  3Q3Q A;  1EW8 A;  3KD8 A;  3M8Y A;  4LR7 A;  1AJB A;  3NKR A;  3UNY A;  4CYS A;  3M8Z A;  2W5Q A;  1ZEF A;  2X98 A;  4UPH A;  4GTX A;  4LRE A;  1EW9 A;  2XR9 A;  1E3C P;  4LRA A;  3UN3 A;  1SHQ A;  2W5R A;  1EW2 A;  2RH6 A;  1N2K A;  3MK0 A;  4FDI A;  1ELY A;  2IFY A;  5LRM A;  1AJA A;  4GTZ A;  1AJC A;  1URB A;  3BDG A;  1KH9 A;  2GLQ A;  5L0K A;  3NVL A;  4MY4 A;  3T01 A;  3UN5 A;  1P49 A;  3TX0 A;  1ALH A;  4KAV A;  4KM4 A;  1K7H A;  3WAX A;  4LQY A;  1KH7 A;  3M8W A;  4KJD A;  1Y7A A;  4ZGA A;  3A52 A;  4GTY A;  1E2S P;  4KAY A;  5EGE A;  1AUK A;  4CYR A;  1ELZ A;  2ANH A;  3T02 A;  4TN0 A;  5LRN A;  4UOP A;  4N7T A;  1KH4 A;  1HJK A;  3NKO A;  4B56 A;  3TG0 A;  4LR8 A;  1ED9 A;  5L0B A;  1ZEB A;  2W5X A;  4CXK A;  1ALJ A;  5LIA A;  4LR2 A;  1N2L A;  5INH A;  1ANI A;  3UO0 A;  3IGZ B;  1HDH A;  3ED4 A;  1EI6 A;  2ZKT A;  1HQA A;  4ZG6 A;  5IJS A;  5GOV A;  2W5W A;  3WAW A;  3IGY B;  2GSU A;  4LRC A;  3DPC A;  5C66 A;  1KHK A;  3LXQ A;  4MIV A;  3IDD A;  4UOO A;  2QZU A;  1O98 A;  4UPK A;  1ALK A;  3BDF A;  3B5Q A;  2GSO A;  4NWX A;  3M7V A;  5K4P A;  1FSU A;  3MK2 A;  1ALI A;  2IUC B;  3DYC A;  4KJG A;  2GSN A;  4LR9 A;  1EJJ A;  3OT9 A;  4UPL A;  2W8S A;  1ZED A;  2W5V A;  1O99 A;  2G9Y A;  3CMR A;  5TJ3 A;  3WAY A;  4QAX A;  1URA A;  1E1Z P;  1EQJ A;  1KHL A;  3NKP A;  4LRD A;  5EGH A;  5GRR A;  1Y6V A;  4LRB A;  4LRF A;  2D1G A;  4NWJ A;  2IUC A;  3SZZ A;  4ZG7 A;  2GA3 A;  4CXS A;  3NKQ A;  5L0E A;  2XRG A;  4ZG9 A;  5DLV A;  4GTW A;  5HRT A;  2W8D A;  3SZY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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