1SHQA

Crystal structure of shrimp alkaline phosphatase with magnesium in m3
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords alkaline phosphatase
publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shqA00
3A52A 1ZEFA 3LXQA 5HRTA 1EW8A 2XR9A 2IFYA 1ED8A 1E33P 4LRFA 1ELZA 2GSUA 1KH4A 4ZGAA 5LQQA 5DLWA 1B8JA 3DPCA 1KHNA 4LRAA 3M8WA 3UN5A 5AJ9A 3T01A 1HJKA 4NWJA 4LREA 3CMRA 1N2LA 4MHXA 5L0KA 2VQRA 2D1GA 5GOVA 5GRRA 4FDJA 4KJDA 3MK0A 3BDFA 3NKOA 5KXAA 2W5TA 3WAYA 2W5WA 4LR8A 4B56A 1ALHA 5LRNA 2GSOA 5LRMA 1ZEBA 3DYCA 3UN3A 4CYRA 1N2KA 3WAVA 1ED9A 3TG0A 4GTYA 1O99A 1EW2A 1P49A 1ALIA 5IJQA 3T00A 3UNYA 3NVLA 2ANHA 5C66A 1SHQA 3UO0A 1E1ZP 1E3CP 4ZG6A 1ALJA 3M8YA 4UORA 2QZUA 4LRDA 3WAXA 4N7TA 1KH5A 3MK2A 1KHLA 2W8DA 3NKMA 3IGZB 1URAA 4UPLA 1EJJA 4LR9A 2W5XA 3ED4A 1HQAA 3TX0A 1HDHA 1EW9A 4UPHA 4CXUA 2RH6A 2GLQA 4YR1A 5DLVA 4LR2A 2ZKTA 4LQYA 4ZG9A 1ANJA 4MY4A 2X98A 4CYSA 1EQJA 4UPIA 5IJSA 3NKRA 1AJAA 3SZZA 5L0EA 1K7HA 3M7VA 3NKNA 2W5SA 3WBHA 1URBA 3SZYA 4CXKA 2IUCA 3E2DA 3UN2A 3B5QA 2GA3A 1ELXA 3IGYB 3NKPA 3IDDA 2GSNA 2G9YA 2W8SA 4KM4A 4FDIA 4GTZA 5EGEA 4GTWA 5TJ3A 2IUCB 1ANIA 4MIVA 1ELYA 1E2SP 1KHKA 3NKQA 1FSUA 2XRGA 3OT9A 1Y7AA 3M8ZA 3WAWA 3Q3QA 5L0BA 3KD8A 4CXSA 2W5QA 1KH7A 5EGHA 3BDHA 1AJDA 4ZG7A 4LR7A 4TN0A 2W5RA 3TWZA 4KJGA 5DLTA 4LRCA 4UOPA 2W5VA 4GTXA 3BDGA 4LRBA 4UOOA 3MK1A 4UPKA 1O98A 4NWXA 4KAVA 1ZEDA 1Y6VA 4QAXA 1AUKA 1SHNA 3T02A 5LIAA 4KAYA 1AJBA 1AJCA 1ALKA 1KHJA 1EI6A 1KH9A 3BDGB 5K4PA 5INHA
chains in the Genus database with same CATH superfamily
3A52A 1ZEFA 3LXQA 5HRTA 1EW8A 2XR9A 2IFYA 1ED8A 1E33P 4LRFA 1ELZA 2GSUA 1KH4A 4ZGAA 5LQQA 5DLWA 1B8JA 3DPCA 1KHNA 4LRAA 3M8WA 3UN5A 5AJ9A 3T01A 1HJKA 4NWJA 4LREA 3CMRA 1N2LA 4MHXA 5L0KA 2VQRA 2D1GA 5GOVA 5GRRA 4FDJA 4KJDA 3MK0A 3BDFA 3NKOA 5KXAA 2W5TA 3WAYA 2W5WA 4LR8A 4B56A 1ALHA 5LRNA 2GSOA 5LRMA 1ZEBA 3DYCA 3UN3A 4CYRA 1N2KA 3WAVA 1ED9A 3TG0A 4GTYA 1O99A 1EW2A 1P49A 1ALIA 5IJQA 3T00A 3UNYA 3NVLA 2ANHA 5C66A 1SHQA 3UO0A 1E1ZP 1E3CP 4ZG6A 1ALJA 3M8YA 4UORA 2QZUA 4LRDA 3WAXA 4N7TA 1KH5A 3MK2A 1KHLA 2W8DA 3NKMA 3IGZB 1URAA 4UPLA 1EJJA 4LR9A 2W5XA 3ED4A 1HQAA 3TX0A 1HDHA 1EW9A 4UPHA 4CXUA 2RH6A 2GLQA 4YR1A 5DLVA 4LR2A 2ZKTA 4LQYA 4ZG9A 1ANJA 4MY4A 2X98A 4CYSA 1EQJA 4UPIA 5IJSA 3NKRA 1AJAA 3SZZA 5L0EA 1K7HA 3M7VA 3NKNA 2W5SA 3WBHA 1URBA 3SZYA 4CXKA 2IUCA 3E2DA 3UN2A 3B5QA 2GA3A 1ELXA 3IGYB 3NKPA 3IDDA 2GSNA 2G9YA 2W8SA 4KM4A 4FDIA 4GTZA 5EGEA 4GTWA 5TJ3A 2IUCB 1ANIA 4MIVA 1ELYA 1E2SP 1KHKA 3NKQA 1FSUA 2XRGA 3OT9A 1Y7AA 3M8ZA 3WAWA 3Q3QA 5L0BA 3KD8A 4CXSA 2W5QA 1KH7A 5EGHA 3BDHA 1AJDA 4ZG7A 4LR7A 4TN0A 2W5RA 3TWZA 4KJGA 5DLTA 4LRCA 4UOPA 2W5VA 4GTXA 3BDGA 4LRBA 4UOOA 3MK1A 4UPKA 1O98A 4NWXA 4KAVA 1ZEDA 1Y6VA 4QAXA 1AUKA 1SHNA 3T02A 5LIAA 4KAYA 1AJBA 1AJCA 1ALKA 1KHJA 1EI6A 1KH9A 3BDGB 5K4PA 5INHA
chains in the Genus database with same CATH topology
3A52A 1ZEFA 3LXQA 5HRTA 1EW8A 2XR9A 2IFYA 1ED8A 1E33P 4LRFA 1ELZA 2GSUA 1KH4A 4ZGAA 5LQQA 5DLWA 1B8JA 3DPCA 1KHNA 4LRAA 3M8WA 3UN5A 5AJ9A 3T01A 1HJKA 4NWJA 4LREA 3CMRA 1N2LA 4MHXA 5L0KA 2VQRA 2D1GA 5GOVA 5GRRA 4FDJA 4KJDA 3MK0A 3BDFA 3NKOA 5KXAA 2W5TA 3WAYA 2W5WA 4LR8A 4B56A 1ALHA 5LRNA 2GSOA 5LRMA 1ZEBA 3DYCA 3UN3A 4CYRA 1N2KA 3WAVA 1ED9A 3TG0A 4GTYA 1O99A 1EW2A 1P49A 1ALIA 5IJQA 3T00A 3UNYA 3NVLA 2ANHA 5C66A 1SHQA 3UO0A 1E1ZP 1E3CP 4ZG6A 1ALJA 3M8YA 4UORA 2QZUA 4LRDA 3WAXA 4N7TA 1KH5A 3MK2A 1KHLA 2W8DA 3NKMA 3IGZB 1URAA 4UPLA 1EJJA 4LR9A 2W5XA 3ED4A 1HQAA 3TX0A 1HDHA 1EW9A 4UPHA 4CXUA 2RH6A 2GLQA 4YR1A 5DLVA 4LR2A 2ZKTA 4LQYA 4ZG9A 1ANJA 4MY4A 2X98A 4CYSA 1EQJA 4UPIA 5IJSA 3NKRA 1AJAA 3SZZA 5L0EA 1K7HA 3M7VA 3NKNA 2W5SA 3WBHA 1URBA 3SZYA 4CXKA 2IUCA 3E2DA 3UN2A 3B5QA 2GA3A 1ELXA 3IGYB 3NKPA 3IDDA 2GSNA 2G9YA 2W8SA 4KM4A 4FDIA 4GTZA 5EGEA 4GTWA 5TJ3A 2IUCB 1ANIA 4MIVA 1ELYA 1E2SP 1KHKA 3NKQA 1FSUA 2XRGA 3OT9A 1Y7AA 3M8ZA 3WAWA 3Q3QA 5L0BA 3KD8A 4CXSA 2W5QA 1KH7A 5EGHA 3BDHA 1AJDA 4ZG7A 4LR7A 4TN0A 2W5RA 3TWZA 4KJGA 5DLTA 4LRCA 4UOPA 2W5VA 4GTXA 3BDGA 4LRBA 4UOOA 3MK1A 4UPKA 1O98A 4NWXA 4KAVA 1ZEDA 1Y6VA 4QAXA 1AUKA 1SHNA 3T02A 5LIAA 4KAYA 1AJBA 1AJCA 1ALKA 1KHJA 1EI6A 1KH9A 3BDGB 5K4PA 5INHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3A52 A;  1ZEF A;  3LXQ A;  5HRT A;  1EW8 A;  2XR9 A;  2IFY A;  1ED8 A;  1E33 P;  4LRF A;  1ELZ A;  2GSU A;  1KH4 A;  4ZGA A;  5LQQ A;  5DLW A;  1B8J A;  3DPC A;  1KHN A;  4LRA A;  3M8W A;  3UN5 A;  5AJ9 A;  3T01 A;  1HJK A;  4NWJ A;  4LRE A;  3CMR A;  1N2L A;  4MHX A;  5L0K A;  2VQR A;  2D1G A;  5GOV A;  5GRR A;  4FDJ A;  4KJD A;  3MK0 A;  3BDF A;  3NKO A;  5KXA A;  2W5T A;  3WAY A;  2W5W A;  4LR8 A;  4B56 A;  1ALH A;  5LRN A;  2GSO A;  5LRM A;  1ZEB A;  3DYC A;  3UN3 A;  4CYR A;  1N2K A;  3WAV A;  1ED9 A;  3TG0 A;  4GTY A;  1O99 A;  1EW2 A;  1P49 A;  1ALI A;  5IJQ A;  3T00 A;  3UNY A;  3NVL A;  2ANH A;  5C66 A;  1SHQ A;  3UO0 A;  1E1Z P;  1E3C P;  4ZG6 A;  1ALJ A;  3M8Y A;  4UOR A;  2QZU A;  4LRD A;  3WAX A;  4N7T A;  1KH5 A;  3MK2 A;  1KHL A;  2W8D A;  3NKM A;  3IGZ B;  1URA A;  4UPL A;  1EJJ A;  4LR9 A;  2W5X A;  3ED4 A;  1HQA A;  3TX0 A;  1HDH A;  1EW9 A;  4UPH A;  4CXU A;  2RH6 A;  2GLQ A;  4YR1 A;  5DLV A;  4LR2 A;  2ZKT A;  4LQY A;  4ZG9 A;  1ANJ A;  4MY4 A;  2X98 A;  4CYS A;  1EQJ A;  4UPI A;  5IJS A;  3NKR A;  1AJA A;  3SZZ A;  5L0E A;  1K7H A;  3M7V A;  3NKN A;  2W5S A;  3WBH A;  1URB A;  3SZY A;  4CXK A;  2IUC A;  3E2D A;  3UN2 A;  3B5Q A;  2GA3 A;  1ELX A;  3IGY B;  3NKP A;  3IDD A;  2GSN A;  2G9Y A;  2W8S A;  4KM4 A;  4FDI A;  4GTZ A;  5EGE A;  4GTW A;  5TJ3 A;  2IUC B;  1ANI A;  4MIV A;  1ELY A;  1E2S P;  1KHK A;  3NKQ A;  1FSU A;  2XRG A;  3OT9 A;  1Y7A A;  3M8Z A;  3WAW A;  3Q3Q A;  5L0B A;  3KD8 A;  4CXS A;  2W5Q A;  1KH7 A;  5EGH A;  3BDH A;  1AJD A;  4ZG7 A;  4LR7 A;  4TN0 A;  2W5R A;  3TWZ A;  4KJG A;  5DLT A;  4LRC A;  4UOP A;  2W5V A;  4GTX A;  3BDG A;  4LRB A;  4UOO A;  3MK1 A;  4UPK A;  1O98 A;  4NWX A;  4KAV A;  1ZED A;  1Y6V A;  4QAX A;  1AUK A;  1SHN A;  3T02 A;  5LIA A;  4KAY A;  1AJB A;  1AJC A;  1ALK A;  1KHJ A;  1EI6 A;  1KH9 A;  3BDG B;  5K4P A;  5INH A; 
#chains in the Genus database with same CATH topology
 3A52 A;  1ZEF A;  3LXQ A;  5HRT A;  1EW8 A;  2XR9 A;  2IFY A;  1ED8 A;  1E33 P;  4LRF A;  1ELZ A;  2GSU A;  1KH4 A;  4ZGA A;  5LQQ A;  5DLW A;  1B8J A;  3DPC A;  1KHN A;  4LRA A;  3M8W A;  3UN5 A;  5AJ9 A;  3T01 A;  1HJK A;  4NWJ A;  4LRE A;  3CMR A;  1N2L A;  4MHX A;  5L0K A;  2VQR A;  2D1G A;  5GOV A;  5GRR A;  4FDJ A;  4KJD A;  3MK0 A;  3BDF A;  3NKO A;  5KXA A;  2W5T A;  3WAY A;  2W5W A;  4LR8 A;  4B56 A;  1ALH A;  5LRN A;  2GSO A;  5LRM A;  1ZEB A;  3DYC A;  3UN3 A;  4CYR A;  1N2K A;  3WAV A;  1ED9 A;  3TG0 A;  4GTY A;  1O99 A;  1EW2 A;  1P49 A;  1ALI A;  5IJQ A;  3T00 A;  3UNY A;  3NVL A;  2ANH A;  5C66 A;  1SHQ A;  3UO0 A;  1E1Z P;  1E3C P;  4ZG6 A;  1ALJ A;  3M8Y A;  4UOR A;  2QZU A;  4LRD A;  3WAX A;  4N7T A;  1KH5 A;  3MK2 A;  1KHL A;  2W8D A;  3NKM A;  3IGZ B;  1URA A;  4UPL A;  1EJJ A;  4LR9 A;  2W5X A;  3ED4 A;  1HQA A;  3TX0 A;  1HDH A;  1EW9 A;  4UPH A;  4CXU A;  2RH6 A;  2GLQ A;  4YR1 A;  5DLV A;  4LR2 A;  2ZKT A;  4LQY A;  4ZG9 A;  1ANJ A;  4MY4 A;  2X98 A;  4CYS A;  1EQJ A;  4UPI A;  5IJS A;  3NKR A;  1AJA A;  3SZZ A;  5L0E A;  1K7H A;  3M7V A;  3NKN A;  2W5S A;  3WBH A;  1URB A;  3SZY A;  4CXK A;  2IUC A;  3E2D A;  3UN2 A;  3B5Q A;  2GA3 A;  1ELX A;  3IGY B;  3NKP A;  3IDD A;  2GSN A;  2G9Y A;  2W8S A;  4KM4 A;  4FDI A;  4GTZ A;  5EGE A;  4GTW A;  5TJ3 A;  2IUC B;  1ANI A;  4MIV A;  1ELY A;  1E2S P;  1KHK A;  3NKQ A;  1FSU A;  2XRG A;  3OT9 A;  1Y7A A;  3M8Z A;  3WAW A;  3Q3Q A;  5L0B A;  3KD8 A;  4CXS A;  2W5Q A;  1KH7 A;  5EGH A;  3BDH A;  1AJD A;  4ZG7 A;  4LR7 A;  4TN0 A;  2W5R A;  3TWZ A;  4KJG A;  5DLT A;  4LRC A;  4UOP A;  2W5V A;  4GTX A;  3BDG A;  4LRB A;  4UOO A;  3MK1 A;  4UPK A;  1O98 A;  4NWX A;  4KAV A;  1ZED A;  1Y6V A;  4QAX A;  1AUK A;  1SHN A;  3T02 A;  5LIA A;  4KAY A;  1AJB A;  1AJC A;  1ALK A;  1KHJ A;  1EI6 A;  1KH9 A;  3BDG B;  5K4P A;  5INH A; 
#chains in the Genus database with same CATH homology
 3A52 A;  1ZEF A;  3LXQ A;  5HRT A;  1EW8 A;  2XR9 A;  2IFY A;  1ED8 A;  1E33 P;  4LRF A;  1ELZ A;  2GSU A;  1KH4 A;  4ZGA A;  5LQQ A;  5DLW A;  1B8J A;  3DPC A;  1KHN A;  4LRA A;  3M8W A;  3UN5 A;  5AJ9 A;  3T01 A;  1HJK A;  4NWJ A;  4LRE A;  3CMR A;  1N2L A;  4MHX A;  5L0K A;  2VQR A;  2D1G A;  5GOV A;  5GRR A;  4FDJ A;  4KJD A;  3MK0 A;  3BDF A;  3NKO A;  5KXA A;  2W5T A;  3WAY A;  2W5W A;  4LR8 A;  4B56 A;  1ALH A;  5LRN A;  2GSO A;  5LRM A;  1ZEB A;  3DYC A;  3UN3 A;  4CYR A;  1N2K A;  3WAV A;  1ED9 A;  3TG0 A;  4GTY A;  1O99 A;  1EW2 A;  1P49 A;  1ALI A;  5IJQ A;  3T00 A;  3UNY A;  3NVL A;  2ANH A;  5C66 A;  1SHQ A;  3UO0 A;  1E1Z P;  1E3C P;  4ZG6 A;  1ALJ A;  3M8Y A;  4UOR A;  2QZU A;  4LRD A;  3WAX A;  4N7T A;  1KH5 A;  3MK2 A;  1KHL A;  2W8D A;  3NKM A;  3IGZ B;  1URA A;  4UPL A;  1EJJ A;  4LR9 A;  2W5X A;  3ED4 A;  1HQA A;  3TX0 A;  1HDH A;  1EW9 A;  4UPH A;  4CXU A;  2RH6 A;  2GLQ A;  4YR1 A;  5DLV A;  4LR2 A;  2ZKT A;  4LQY A;  4ZG9 A;  1ANJ A;  4MY4 A;  2X98 A;  4CYS A;  1EQJ A;  4UPI A;  5IJS A;  3NKR A;  1AJA A;  3SZZ A;  5L0E A;  1K7H A;  3M7V A;  3NKN A;  2W5S A;  3WBH A;  1URB A;  3SZY A;  4CXK A;  2IUC A;  3E2D A;  3UN2 A;  3B5Q A;  2GA3 A;  1ELX A;  3IGY B;  3NKP A;  3IDD A;  2GSN A;  2G9Y A;  2W8S A;  4KM4 A;  4FDI A;  4GTZ A;  5EGE A;  4GTW A;  5TJ3 A;  2IUC B;  1ANI A;  4MIV A;  1ELY A;  1E2S P;  1KHK A;  3NKQ A;  1FSU A;  2XRG A;  3OT9 A;  1Y7A A;  3M8Z A;  3WAW A;  3Q3Q A;  5L0B A;  3KD8 A;  4CXS A;  2W5Q A;  1KH7 A;  5EGH A;  3BDH A;  1AJD A;  4ZG7 A;  4LR7 A;  4TN0 A;  2W5R A;  3TWZ A;  4KJG A;  5DLT A;  4LRC A;  4UOP A;  2W5V A;  4GTX A;  3BDG A;  4LRB A;  4UOO A;  3MK1 A;  4UPK A;  1O98 A;  4NWX A;  4KAV A;  1ZED A;  1Y6V A;  4QAX A;  1AUK A;  1SHN A;  3T02 A;  5LIA A;  4KAY A;  1AJB A;  1AJC A;  1ALK A;  1KHJ A;  1EI6 A;  1KH9 A;  3BDG B;  5K4P A;  5INH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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