1SHQA

Crystal structure of shrimp alkaline phosphatase with magnesium in m3
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords alkaline phosphatase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shqA00
4CYSA 1N2LA 1KH7A 3MK0A 1AJDA 1KH5A 3MK1A 4LR9A 3SZYA 2VQRA 3WAWA 1KHKA 1KHLA 1ANIA 5C66A 4YR1A 3BDFA 3M8YA 4GTWA 4UORA 1E1ZP 5KXAA 1E3CP 4GTXA 3UN2A 2W5WA 3NKPA 5IJQA 4FDIA 3WAYA 5LIAA 5L0KA 2ANHA 1FSUA 1AJBA 3NKMA 1SHNA 1Y7AA 4MY4A 4CXUA 5GOVA 4KM4A 3WAVA 3T00A 1E33P 4LR8A 4LREA 1KH4A 2W5SA 4LR2A 1O99A 3LXQA 3DYCA 4CYRA 1ZEBA 2W8DA 4KAVA 3UO0A 3BDGA 4FDJA 3IDDA 1ZEFA 4TN0A 4CXSA 3NKOA 4LRCA 1P49A 5INHA 2W5QA 2QZUA 1ED9A 3M7VA 2W5RA 3IGZB 1B8JA 2W5VA 4UPIA 1ALKA 3NVLA 3NKRA 1K7HA 4LRBA 4CXKA 5HRTA 5TJ3A 5EGHA 3BDGB 1ALJA 3UNYA 3BDHA 4KAYA 4LR7A 1ELZA 4LRDA 1KH9A 3A52A 3E2DA 4KJDA 3ED4A 3TWZA 1EW9A 1Y6VA 3T02A 1HQAA 5LRMA 4N7TA 5AJ9A 2IFYA 3OT9A 4UPLA 1KHJA 1HJKA 5DLVA 5DLTA 5IJSA 2W5TA 5GRRA 1ALIA 1URAA 3SZZA 2W5XA 5K4PA 4UOOA 1ELYA 1EW8A 3T01A 5L0EA 3IGYB 1AJAA 4UOPA 3NKNA 1ALHA 1HDHA 1SHQA 5DLWA 3Q3QA 1EI6A 5LQQA 2GSOA 1EW2A 2D1GA 2XRGA 4GTZA 4ZG9A 3M8ZA 2XR9A 3TX0A 3DPCA 3MK2A 2G9YA 1ELXA 2GSNA 2GLQA 2GA3A 4MIVA 3UN5A 4ZG6A 3TG0A 1ED8A 1EJJA 2IUCA 1AUKA 1O98A 4B56A 3WBHA 5L0BA 4GTYA 3CMRA 4UPHA 2X98A 4QAXA 3NKQA 4NWJA 4ZG7A 4KJGA 5EGEA 4ZGAA 3KD8A 4UPKA 1E2SP 2RH6A 4LRFA 2GSUA 1ANJA 1EQJA 1AJCA 3UN3A 1ZEDA 5LRNA 1KHNA 2IUCB 4LQYA 3WAXA 3M8WA 4MHXA 3B5QA 1URBA 1N2KA 2W8SA 4LRAA 4NWXA 2ZKTA
chains in the Genus database with same CATH superfamily
4CYSA 1N2LA 1KH7A 3MK0A 1AJDA 1KH5A 3MK1A 4LR9A 3SZYA 2VQRA 3WAWA 1KHKA 1KHLA 1ANIA 5C66A 4YR1A 3BDFA 3M8YA 4GTWA 4UORA 1E1ZP 5KXAA 1E3CP 4GTXA 3UN2A 2W5WA 3NKPA 5IJQA 4FDIA 3WAYA 5LIAA 5L0KA 2ANHA 1FSUA 1AJBA 3NKMA 1SHNA 1Y7AA 4MY4A 4CXUA 5GOVA 4KM4A 3WAVA 3T00A 1E33P 4LR8A 4LREA 1KH4A 2W5SA 4LR2A 1O99A 3LXQA 3DYCA 4CYRA 1ZEBA 2W8DA 4KAVA 3UO0A 3BDGA 4FDJA 3IDDA 1ZEFA 4TN0A 4CXSA 3NKOA 4LRCA 1P49A 5INHA 2W5QA 2QZUA 1ED9A 3M7VA 2W5RA 3IGZB 1B8JA 2W5VA 4UPIA 1ALKA 3NVLA 3NKRA 1K7HA 4LRBA 4CXKA 5HRTA 5TJ3A 5EGHA 3BDGB 1ALJA 3UNYA 3BDHA 4KAYA 4LR7A 1ELZA 4LRDA 1KH9A 3A52A 3E2DA 4KJDA 3ED4A 3TWZA 1EW9A 1Y6VA 3T02A 1HQAA 5LRMA 4N7TA 5AJ9A 2IFYA 3OT9A 4UPLA 1KHJA 1HJKA 5DLVA 5DLTA 5IJSA 2W5TA 5GRRA 1ALIA 1URAA 3SZZA 2W5XA 5K4PA 4UOOA 1ELYA 1EW8A 3T01A 5L0EA 3IGYB 1AJAA 4UOPA 3NKNA 1ALHA 1HDHA 1SHQA 5DLWA 3Q3QA 1EI6A 5LQQA 2GSOA 1EW2A 2D1GA 2XRGA 4GTZA 4ZG9A 3M8ZA 2XR9A 3TX0A 3DPCA 3MK2A 2G9YA 1ELXA 2GSNA 2GLQA 2GA3A 4MIVA 3UN5A 4ZG6A 3TG0A 1ED8A 1EJJA 2IUCA 1AUKA 1O98A 4B56A 3WBHA 5L0BA 4GTYA 3CMRA 4UPHA 2X98A 4QAXA 3NKQA 4NWJA 4ZG7A 4KJGA 5EGEA 4ZGAA 3KD8A 4UPKA 1E2SP 2RH6A 4LRFA 2GSUA 1ANJA 1EQJA 1AJCA 3UN3A 1ZEDA 5LRNA 1KHNA 2IUCB 4LQYA 3WAXA 3M8WA 4MHXA 3B5QA 1URBA 1N2KA 2W8SA 4LRAA 4NWXA 2ZKTA
chains in the Genus database with same CATH topology
4CYSA 1N2LA 1KH7A 3MK0A 1AJDA 1KH5A 3MK1A 4LR9A 3SZYA 2VQRA 3WAWA 1KHKA 1KHLA 1ANIA 5C66A 4YR1A 3BDFA 3M8YA 4GTWA 4UORA 1E1ZP 5KXAA 1E3CP 4GTXA 3UN2A 2W5WA 3NKPA 5IJQA 4FDIA 3WAYA 5LIAA 5L0KA 2ANHA 1FSUA 1AJBA 3NKMA 1SHNA 1Y7AA 4MY4A 4CXUA 5GOVA 4KM4A 3WAVA 3T00A 1E33P 4LR8A 4LREA 1KH4A 2W5SA 4LR2A 1O99A 3LXQA 3DYCA 4CYRA 1ZEBA 2W8DA 4KAVA 3UO0A 3BDGA 4FDJA 3IDDA 1ZEFA 4TN0A 4CXSA 3NKOA 4LRCA 1P49A 5INHA 2W5QA 2QZUA 1ED9A 3M7VA 2W5RA 3IGZB 1B8JA 2W5VA 4UPIA 1ALKA 3NVLA 3NKRA 1K7HA 4LRBA 4CXKA 5HRTA 5TJ3A 5EGHA 3BDGB 1ALJA 3UNYA 3BDHA 4KAYA 4LR7A 1ELZA 4LRDA 1KH9A 3A52A 3E2DA 4KJDA 3ED4A 3TWZA 1EW9A 1Y6VA 3T02A 1HQAA 5LRMA 4N7TA 5AJ9A 2IFYA 3OT9A 4UPLA 1KHJA 1HJKA 5DLVA 5DLTA 5IJSA 2W5TA 5GRRA 1ALIA 1URAA 3SZZA 2W5XA 5K4PA 4UOOA 1ELYA 1EW8A 3T01A 5L0EA 3IGYB 1AJAA 4UOPA 3NKNA 1ALHA 1HDHA 1SHQA 5DLWA 3Q3QA 1EI6A 5LQQA 2GSOA 1EW2A 2D1GA 2XRGA 4GTZA 4ZG9A 3M8ZA 2XR9A 3TX0A 3DPCA 3MK2A 2G9YA 1ELXA 2GSNA 2GLQA 2GA3A 4MIVA 3UN5A 4ZG6A 3TG0A 1ED8A 1EJJA 2IUCA 1AUKA 1O98A 4B56A 3WBHA 5L0BA 4GTYA 3CMRA 4UPHA 2X98A 4QAXA 3NKQA 4NWJA 4ZG7A 4KJGA 5EGEA 4ZGAA 3KD8A 4UPKA 1E2SP 2RH6A 4LRFA 2GSUA 1ANJA 1EQJA 1AJCA 3UN3A 1ZEDA 5LRNA 1KHNA 2IUCB 4LQYA 3WAXA 3M8WA 4MHXA 3B5QA 1URBA 1N2KA 2W8SA 4LRAA 4NWXA 2ZKTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CYS A;  1N2L A;  1KH7 A;  3MK0 A;  1AJD A;  1KH5 A;  3MK1 A;  4LR9 A;  3SZY A;  2VQR A;  3WAW A;  1KHK A;  1KHL A;  1ANI A;  5C66 A;  4YR1 A;  3BDF A;  3M8Y A;  4GTW A;  4UOR A;  1E1Z P;  5KXA A;  1E3C P;  4GTX A;  3UN2 A;  2W5W A;  3NKP A;  5IJQ A;  4FDI A;  3WAY A;  5LIA A;  5L0K A;  2ANH A;  1FSU A;  1AJB A;  3NKM A;  1SHN A;  1Y7A A;  4MY4 A;  4CXU A;  5GOV A;  4KM4 A;  3WAV A;  3T00 A;  1E33 P;  4LR8 A;  4LRE A;  1KH4 A;  2W5S A;  4LR2 A;  1O99 A;  3LXQ A;  3DYC A;  4CYR A;  1ZEB A;  2W8D A;  4KAV A;  3UO0 A;  3BDG A;  4FDJ A;  3IDD A;  1ZEF A;  4TN0 A;  4CXS A;  3NKO A;  4LRC A;  1P49 A;  5INH A;  2W5Q A;  2QZU A;  1ED9 A;  3M7V A;  2W5R A;  3IGZ B;  1B8J A;  2W5V A;  4UPI A;  1ALK A;  3NVL A;  3NKR A;  1K7H A;  4LRB A;  4CXK A;  5HRT A;  5TJ3 A;  5EGH A;  3BDG B;  1ALJ A;  3UNY A;  3BDH A;  4KAY A;  4LR7 A;  1ELZ A;  4LRD A;  1KH9 A;  3A52 A;  3E2D A;  4KJD A;  3ED4 A;  3TWZ A;  1EW9 A;  1Y6V A;  3T02 A;  1HQA A;  5LRM A;  4N7T A;  5AJ9 A;  2IFY A;  3OT9 A;  4UPL A;  1KHJ A;  1HJK A;  5DLV A;  5DLT A;  5IJS A;  2W5T A;  5GRR A;  1ALI A;  1URA A;  3SZZ A;  2W5X A;  5K4P A;  4UOO A;  1ELY A;  1EW8 A;  3T01 A;  5L0E A;  3IGY B;  1AJA A;  4UOP A;  3NKN A;  1ALH A;  1HDH A;  1SHQ A;  5DLW A;  3Q3Q A;  1EI6 A;  5LQQ A;  2GSO A;  1EW2 A;  2D1G A;  2XRG A;  4GTZ A;  4ZG9 A;  3M8Z A;  2XR9 A;  3TX0 A;  3DPC A;  3MK2 A;  2G9Y A;  1ELX A;  2GSN A;  2GLQ A;  2GA3 A;  4MIV A;  3UN5 A;  4ZG6 A;  3TG0 A;  1ED8 A;  1EJJ A;  2IUC A;  1AUK A;  1O98 A;  4B56 A;  3WBH A;  5L0B A;  4GTY A;  3CMR A;  4UPH A;  2X98 A;  4QAX A;  3NKQ A;  4NWJ A;  4ZG7 A;  4KJG A;  5EGE A;  4ZGA A;  3KD8 A;  4UPK A;  1E2S P;  2RH6 A;  4LRF A;  2GSU A;  1ANJ A;  1EQJ A;  1AJC A;  3UN3 A;  1ZED A;  5LRN A;  1KHN A;  2IUC B;  4LQY A;  3WAX A;  3M8W A;  4MHX A;  3B5Q A;  1URB A;  1N2K A;  2W8S A;  4LRA A;  4NWX A;  2ZKT A; 
#chains in the Genus database with same CATH topology
 4CYS A;  1N2L A;  1KH7 A;  3MK0 A;  1AJD A;  1KH5 A;  3MK1 A;  4LR9 A;  3SZY A;  2VQR A;  3WAW A;  1KHK A;  1KHL A;  1ANI A;  5C66 A;  4YR1 A;  3BDF A;  3M8Y A;  4GTW A;  4UOR A;  1E1Z P;  5KXA A;  1E3C P;  4GTX A;  3UN2 A;  2W5W A;  3NKP A;  5IJQ A;  4FDI A;  3WAY A;  5LIA A;  5L0K A;  2ANH A;  1FSU A;  1AJB A;  3NKM A;  1SHN A;  1Y7A A;  4MY4 A;  4CXU A;  5GOV A;  4KM4 A;  3WAV A;  3T00 A;  1E33 P;  4LR8 A;  4LRE A;  1KH4 A;  2W5S A;  4LR2 A;  1O99 A;  3LXQ A;  3DYC A;  4CYR A;  1ZEB A;  2W8D A;  4KAV A;  3UO0 A;  3BDG A;  4FDJ A;  3IDD A;  1ZEF A;  4TN0 A;  4CXS A;  3NKO A;  4LRC A;  1P49 A;  5INH A;  2W5Q A;  2QZU A;  1ED9 A;  3M7V A;  2W5R A;  3IGZ B;  1B8J A;  2W5V A;  4UPI A;  1ALK A;  3NVL A;  3NKR A;  1K7H A;  4LRB A;  4CXK A;  5HRT A;  5TJ3 A;  5EGH A;  3BDG B;  1ALJ A;  3UNY A;  3BDH A;  4KAY A;  4LR7 A;  1ELZ A;  4LRD A;  1KH9 A;  3A52 A;  3E2D A;  4KJD A;  3ED4 A;  3TWZ A;  1EW9 A;  1Y6V A;  3T02 A;  1HQA A;  5LRM A;  4N7T A;  5AJ9 A;  2IFY A;  3OT9 A;  4UPL A;  1KHJ A;  1HJK A;  5DLV A;  5DLT A;  5IJS A;  2W5T A;  5GRR A;  1ALI A;  1URA A;  3SZZ A;  2W5X A;  5K4P A;  4UOO A;  1ELY A;  1EW8 A;  3T01 A;  5L0E A;  3IGY B;  1AJA A;  4UOP A;  3NKN A;  1ALH A;  1HDH A;  1SHQ A;  5DLW A;  3Q3Q A;  1EI6 A;  5LQQ A;  2GSO A;  1EW2 A;  2D1G A;  2XRG A;  4GTZ A;  4ZG9 A;  3M8Z A;  2XR9 A;  3TX0 A;  3DPC A;  3MK2 A;  2G9Y A;  1ELX A;  2GSN A;  2GLQ A;  2GA3 A;  4MIV A;  3UN5 A;  4ZG6 A;  3TG0 A;  1ED8 A;  1EJJ A;  2IUC A;  1AUK A;  1O98 A;  4B56 A;  3WBH A;  5L0B A;  4GTY A;  3CMR A;  4UPH A;  2X98 A;  4QAX A;  3NKQ A;  4NWJ A;  4ZG7 A;  4KJG A;  5EGE A;  4ZGA A;  3KD8 A;  4UPK A;  1E2S P;  2RH6 A;  4LRF A;  2GSU A;  1ANJ A;  1EQJ A;  1AJC A;  3UN3 A;  1ZED A;  5LRN A;  1KHN A;  2IUC B;  4LQY A;  3WAX A;  3M8W A;  4MHX A;  3B5Q A;  1URB A;  1N2K A;  2W8S A;  4LRA A;  4NWX A;  2ZKT A; 
#chains in the Genus database with same CATH homology
 4CYS A;  1N2L A;  1KH7 A;  3MK0 A;  1AJD A;  1KH5 A;  3MK1 A;  4LR9 A;  3SZY A;  2VQR A;  3WAW A;  1KHK A;  1KHL A;  1ANI A;  5C66 A;  4YR1 A;  3BDF A;  3M8Y A;  4GTW A;  4UOR A;  1E1Z P;  5KXA A;  1E3C P;  4GTX A;  3UN2 A;  2W5W A;  3NKP A;  5IJQ A;  4FDI A;  3WAY A;  5LIA A;  5L0K A;  2ANH A;  1FSU A;  1AJB A;  3NKM A;  1SHN A;  1Y7A A;  4MY4 A;  4CXU A;  5GOV A;  4KM4 A;  3WAV A;  3T00 A;  1E33 P;  4LR8 A;  4LRE A;  1KH4 A;  2W5S A;  4LR2 A;  1O99 A;  3LXQ A;  3DYC A;  4CYR A;  1ZEB A;  2W8D A;  4KAV A;  3UO0 A;  3BDG A;  4FDJ A;  3IDD A;  1ZEF A;  4TN0 A;  4CXS A;  3NKO A;  4LRC A;  1P49 A;  5INH A;  2W5Q A;  2QZU A;  1ED9 A;  3M7V A;  2W5R A;  3IGZ B;  1B8J A;  2W5V A;  4UPI A;  1ALK A;  3NVL A;  3NKR A;  1K7H A;  4LRB A;  4CXK A;  5HRT A;  5TJ3 A;  5EGH A;  3BDG B;  1ALJ A;  3UNY A;  3BDH A;  4KAY A;  4LR7 A;  1ELZ A;  4LRD A;  1KH9 A;  3A52 A;  3E2D A;  4KJD A;  3ED4 A;  3TWZ A;  1EW9 A;  1Y6V A;  3T02 A;  1HQA A;  5LRM A;  4N7T A;  5AJ9 A;  2IFY A;  3OT9 A;  4UPL A;  1KHJ A;  1HJK A;  5DLV A;  5DLT A;  5IJS A;  2W5T A;  5GRR A;  1ALI A;  1URA A;  3SZZ A;  2W5X A;  5K4P A;  4UOO A;  1ELY A;  1EW8 A;  3T01 A;  5L0E A;  3IGY B;  1AJA A;  4UOP A;  3NKN A;  1ALH A;  1HDH A;  1SHQ A;  5DLW A;  3Q3Q A;  1EI6 A;  5LQQ A;  2GSO A;  1EW2 A;  2D1G A;  2XRG A;  4GTZ A;  4ZG9 A;  3M8Z A;  2XR9 A;  3TX0 A;  3DPC A;  3MK2 A;  2G9Y A;  1ELX A;  2GSN A;  2GLQ A;  2GA3 A;  4MIV A;  3UN5 A;  4ZG6 A;  3TG0 A;  1ED8 A;  1EJJ A;  2IUC A;  1AUK A;  1O98 A;  4B56 A;  3WBH A;  5L0B A;  4GTY A;  3CMR A;  4UPH A;  2X98 A;  4QAX A;  3NKQ A;  4NWJ A;  4ZG7 A;  4KJG A;  5EGE A;  4ZGA A;  3KD8 A;  4UPK A;  1E2S P;  2RH6 A;  4LRF A;  2GSU A;  1ANJ A;  1EQJ A;  1AJC A;  3UN3 A;  1ZED A;  5LRN A;  1KHN A;  2IUC B;  4LQY A;  3WAX A;  3M8W A;  4MHX A;  3B5Q A;  1URB A;  1N2K A;  2W8S A;  4LRA A;  4NWX A;  2ZKT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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