1ELZA

E. coli alkaline phosphatase mutant (s102g)
Total Genus 157
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
157
Knots found
sequence length
449
structure length
449
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDGAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords ALKALINE PHOSPHATASE
publication title Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 157
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1998-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1elzA00
1KH5A 2ANHA 5LRMA 3WAVA 4LR9A 3SZZA 3BDGB 3B5QA 4LRDA 4ZG9A 1ZEFA 1KH9A 3MK1A 3UN3A 2GSUA 4GTWA 1N2KA 4TN0A 4UORA 1ALHA 1O99A 3TG0A 4CXKA 4UPLA 1E2SP 4LRBA 5HRTA 1FSUA 1E1ZP 4GTYA 1ELXA 2W5QA 2IFYA 1EW2A 3MK2A 5INHA 4KAYA 4MIVA 3NKNA 3T02A 3BDGA 3WAYA 3MK0A 2W5RA 1KHKA 1HJKA 5GRRA 4GTZA 1ED9A 2GA3A 2GSNA 2W5VA 3BDHA 3NKQA 3T00A 4UPIA 3CMRA 3T01A 3UN2A 5DLVA 1AJDA 1AJAA 1SHNA 1ELYA 1URBA 5TJ3A 3A52A 4CYSA 1O98A 1ALKA 5DLWA 5EGEA 4LREA 5L0KA 1B8JA 2IUCB 2G9YA 1EQJA 5LRNA 4UOPA 4UPHA 4B56A 1Y6VA 3NKMA 3Q3QA 5GOVA 1URAA 1AJCA 1KHLA 2RH6A 3IGZB 1E3CP 5K4PA 3UNYA 1ALJA 4ZGAA 4LRCA 3NKRA 5KXAA 5DLTA 3NKOA 3E2DA 4GTXA 3DYCA 3WAWA 4CXUA 3UN5A 1KH4A 1EW9A 4YR1A 5C66A 4ZG6A 3WBHA 2QZUA 3M8YA 1EW8A 3LXQA 3NVLA 4FDJA 4KAVA 5L0BA 3SZYA 3OT9A 4NWJA 4CXSA 1ELZA 2IUCA 3BDFA 4ZG7A 1EJJA 1HQAA 1ZEBA 2VQRA 3M8WA 4N7TA 2W8SA 3IDDA 4LRFA 4QAXA 4KM4A 4LR8A 3TWZA 5LIAA 5IJSA 2ZKTA 2GLQA 1K7HA 5L0EA 1SHQA 1Y7AA 3M7VA 4MY4A 5AJ9A 1N2LA 1KH7A 5IJQA 4UOOA 4LR7A 3DPCA 2GSOA 1P49A 2W5SA 4LQYA 4LR2A 1ANJA 4KJGA 1HDHA 3WAXA 1ANIA 5EGHA 2X98A 3TX0A 3NKPA 1ZEDA 3IGYB 2XR9A 5LQQA 4MHXA 1KHJA 2W5WA 2W5TA 4NWXA 1KHNA 1E33P 3KD8A 4UPKA 2W8DA 1AUKA 4CYRA 1ALIA 4LRAA 4KJDA 1ED8A 3ED4A 4FDIA 1AJBA 2D1GA 2W5XA 1EI6A 2XRGA 3M8ZA 3UO0A
chains in the Genus database with same CATH superfamily
1KH5A 2ANHA 5LRMA 3WAVA 4LR9A 3SZZA 3BDGB 3B5QA 4LRDA 4ZG9A 1ZEFA 1KH9A 3MK1A 3UN3A 2GSUA 4GTWA 1N2KA 4TN0A 4UORA 1ALHA 1O99A 3TG0A 4CXKA 4UPLA 1E2SP 4LRBA 5HRTA 1FSUA 1E1ZP 4GTYA 1ELXA 2W5QA 2IFYA 1EW2A 3MK2A 5INHA 4KAYA 4MIVA 3NKNA 3T02A 3BDGA 3WAYA 3MK0A 2W5RA 1KHKA 1HJKA 5GRRA 4GTZA 1ED9A 2GA3A 2GSNA 2W5VA 3BDHA 3NKQA 3T00A 4UPIA 3CMRA 3T01A 3UN2A 5DLVA 1AJDA 1AJAA 1SHNA 1ELYA 1URBA 5TJ3A 3A52A 4CYSA 1O98A 1ALKA 5DLWA 5EGEA 4LREA 5L0KA 1B8JA 2IUCB 2G9YA 1EQJA 5LRNA 4UOPA 4UPHA 4B56A 1Y6VA 3NKMA 3Q3QA 5GOVA 1URAA 1AJCA 1KHLA 2RH6A 3IGZB 1E3CP 5K4PA 3UNYA 1ALJA 4ZGAA 4LRCA 3NKRA 5KXAA 5DLTA 3NKOA 3E2DA 4GTXA 3DYCA 3WAWA 4CXUA 3UN5A 1KH4A 1EW9A 4YR1A 5C66A 4ZG6A 3WBHA 2QZUA 3M8YA 1EW8A 3LXQA 3NVLA 4FDJA 4KAVA 5L0BA 3SZYA 3OT9A 4NWJA 4CXSA 1ELZA 2IUCA 3BDFA 4ZG7A 1EJJA 1HQAA 1ZEBA 2VQRA 3M8WA 4N7TA 2W8SA 3IDDA 4LRFA 4QAXA 4KM4A 4LR8A 3TWZA 5LIAA 5IJSA 2ZKTA 2GLQA 1K7HA 5L0EA 1SHQA 1Y7AA 3M7VA 4MY4A 5AJ9A 1N2LA 1KH7A 5IJQA 4UOOA 4LR7A 3DPCA 2GSOA 1P49A 2W5SA 4LQYA 4LR2A 1ANJA 4KJGA 1HDHA 3WAXA 1ANIA 5EGHA 2X98A 3TX0A 3NKPA 1ZEDA 3IGYB 2XR9A 5LQQA 4MHXA 1KHJA 2W5WA 2W5TA 4NWXA 1KHNA 1E33P 3KD8A 4UPKA 2W8DA 1AUKA 4CYRA 1ALIA 4LRAA 4KJDA 1ED8A 3ED4A 4FDIA 1AJBA 2D1GA 2W5XA 1EI6A 2XRGA 3M8ZA 3UO0A
chains in the Genus database with same CATH topology
1KH5A 2ANHA 5LRMA 3WAVA 4LR9A 3SZZA 3BDGB 3B5QA 4LRDA 4ZG9A 1ZEFA 1KH9A 3MK1A 3UN3A 2GSUA 4GTWA 1N2KA 4TN0A 4UORA 1ALHA 1O99A 3TG0A 4CXKA 4UPLA 1E2SP 4LRBA 5HRTA 1FSUA 1E1ZP 4GTYA 1ELXA 2W5QA 2IFYA 1EW2A 3MK2A 5INHA 4KAYA 4MIVA 3NKNA 3T02A 3BDGA 3WAYA 3MK0A 2W5RA 1KHKA 1HJKA 5GRRA 4GTZA 1ED9A 2GA3A 2GSNA 2W5VA 3BDHA 3NKQA 3T00A 4UPIA 3CMRA 3T01A 3UN2A 5DLVA 1AJDA 1AJAA 1SHNA 1ELYA 1URBA 5TJ3A 3A52A 4CYSA 1O98A 1ALKA 5DLWA 5EGEA 4LREA 5L0KA 1B8JA 2IUCB 2G9YA 1EQJA 5LRNA 4UOPA 4UPHA 4B56A 1Y6VA 3NKMA 3Q3QA 5GOVA 1URAA 1AJCA 1KHLA 2RH6A 3IGZB 1E3CP 5K4PA 3UNYA 1ALJA 4ZGAA 4LRCA 3NKRA 5KXAA 5DLTA 3NKOA 3E2DA 4GTXA 3DYCA 3WAWA 4CXUA 3UN5A 1KH4A 1EW9A 4YR1A 5C66A 4ZG6A 3WBHA 2QZUA 3M8YA 1EW8A 3LXQA 3NVLA 4FDJA 4KAVA 5L0BA 3SZYA 3OT9A 4NWJA 4CXSA 1ELZA 2IUCA 3BDFA 4ZG7A 1EJJA 1HQAA 1ZEBA 2VQRA 3M8WA 4N7TA 2W8SA 3IDDA 4LRFA 4QAXA 4KM4A 4LR8A 3TWZA 5LIAA 5IJSA 2ZKTA 2GLQA 1K7HA 5L0EA 1SHQA 1Y7AA 3M7VA 4MY4A 5AJ9A 1N2LA 1KH7A 5IJQA 4UOOA 4LR7A 3DPCA 2GSOA 1P49A 2W5SA 4LQYA 4LR2A 1ANJA 4KJGA 1HDHA 3WAXA 1ANIA 5EGHA 2X98A 3TX0A 3NKPA 1ZEDA 3IGYB 2XR9A 5LQQA 4MHXA 1KHJA 2W5WA 2W5TA 4NWXA 1KHNA 1E33P 3KD8A 4UPKA 2W8DA 1AUKA 4CYRA 1ALIA 4LRAA 4KJDA 1ED8A 3ED4A 4FDIA 1AJBA 2D1GA 2W5XA 1EI6A 2XRGA 3M8ZA 3UO0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KH5 A;  2ANH A;  5LRM A;  3WAV A;  4LR9 A;  3SZZ A;  3BDG B;  3B5Q A;  4LRD A;  4ZG9 A;  1ZEF A;  1KH9 A;  3MK1 A;  3UN3 A;  2GSU A;  4GTW A;  1N2K A;  4TN0 A;  4UOR A;  1ALH A;  1O99 A;  3TG0 A;  4CXK A;  4UPL A;  1E2S P;  4LRB A;  5HRT A;  1FSU A;  1E1Z P;  4GTY A;  1ELX A;  2W5Q A;  2IFY A;  1EW2 A;  3MK2 A;  5INH A;  4KAY A;  4MIV A;  3NKN A;  3T02 A;  3BDG A;  3WAY A;  3MK0 A;  2W5R A;  1KHK A;  1HJK A;  5GRR A;  4GTZ A;  1ED9 A;  2GA3 A;  2GSN A;  2W5V A;  3BDH A;  3NKQ A;  3T00 A;  4UPI A;  3CMR A;  3T01 A;  3UN2 A;  5DLV A;  1AJD A;  1AJA A;  1SHN A;  1ELY A;  1URB A;  5TJ3 A;  3A52 A;  4CYS A;  1O98 A;  1ALK A;  5DLW A;  5EGE A;  4LRE A;  5L0K A;  1B8J A;  2IUC B;  2G9Y A;  1EQJ A;  5LRN A;  4UOP A;  4UPH A;  4B56 A;  1Y6V A;  3NKM A;  3Q3Q A;  5GOV A;  1URA A;  1AJC A;  1KHL A;  2RH6 A;  3IGZ B;  1E3C P;  5K4P A;  3UNY A;  1ALJ A;  4ZGA A;  4LRC A;  3NKR A;  5KXA A;  5DLT A;  3NKO A;  3E2D A;  4GTX A;  3DYC A;  3WAW A;  4CXU A;  3UN5 A;  1KH4 A;  1EW9 A;  4YR1 A;  5C66 A;  4ZG6 A;  3WBH A;  2QZU A;  3M8Y A;  1EW8 A;  3LXQ A;  3NVL A;  4FDJ A;  4KAV A;  5L0B A;  3SZY A;  3OT9 A;  4NWJ A;  4CXS A;  1ELZ A;  2IUC A;  3BDF A;  4ZG7 A;  1EJJ A;  1HQA A;  1ZEB A;  2VQR A;  3M8W A;  4N7T A;  2W8S A;  3IDD A;  4LRF A;  4QAX A;  4KM4 A;  4LR8 A;  3TWZ A;  5LIA A;  5IJS A;  2ZKT A;  2GLQ A;  1K7H A;  5L0E A;  1SHQ A;  1Y7A A;  3M7V A;  4MY4 A;  5AJ9 A;  1N2L A;  1KH7 A;  5IJQ A;  4UOO A;  4LR7 A;  3DPC A;  2GSO A;  1P49 A;  2W5S A;  4LQY A;  4LR2 A;  1ANJ A;  4KJG A;  1HDH A;  3WAX A;  1ANI A;  5EGH A;  2X98 A;  3TX0 A;  3NKP A;  1ZED A;  3IGY B;  2XR9 A;  5LQQ A;  4MHX A;  1KHJ A;  2W5W A;  2W5T A;  4NWX A;  1KHN A;  1E33 P;  3KD8 A;  4UPK A;  2W8D A;  1AUK A;  4CYR A;  1ALI A;  4LRA A;  4KJD A;  1ED8 A;  3ED4 A;  4FDI A;  1AJB A;  2D1G A;  2W5X A;  1EI6 A;  2XRG A;  3M8Z A;  3UO0 A; 
#chains in the Genus database with same CATH topology
 1KH5 A;  2ANH A;  5LRM A;  3WAV A;  4LR9 A;  3SZZ A;  3BDG B;  3B5Q A;  4LRD A;  4ZG9 A;  1ZEF A;  1KH9 A;  3MK1 A;  3UN3 A;  2GSU A;  4GTW A;  1N2K A;  4TN0 A;  4UOR A;  1ALH A;  1O99 A;  3TG0 A;  4CXK A;  4UPL A;  1E2S P;  4LRB A;  5HRT A;  1FSU A;  1E1Z P;  4GTY A;  1ELX A;  2W5Q A;  2IFY A;  1EW2 A;  3MK2 A;  5INH A;  4KAY A;  4MIV A;  3NKN A;  3T02 A;  3BDG A;  3WAY A;  3MK0 A;  2W5R A;  1KHK A;  1HJK A;  5GRR A;  4GTZ A;  1ED9 A;  2GA3 A;  2GSN A;  2W5V A;  3BDH A;  3NKQ A;  3T00 A;  4UPI A;  3CMR A;  3T01 A;  3UN2 A;  5DLV A;  1AJD A;  1AJA A;  1SHN A;  1ELY A;  1URB A;  5TJ3 A;  3A52 A;  4CYS A;  1O98 A;  1ALK A;  5DLW A;  5EGE A;  4LRE A;  5L0K A;  1B8J A;  2IUC B;  2G9Y A;  1EQJ A;  5LRN A;  4UOP A;  4UPH A;  4B56 A;  1Y6V A;  3NKM A;  3Q3Q A;  5GOV A;  1URA A;  1AJC A;  1KHL A;  2RH6 A;  3IGZ B;  1E3C P;  5K4P A;  3UNY A;  1ALJ A;  4ZGA A;  4LRC A;  3NKR A;  5KXA A;  5DLT A;  3NKO A;  3E2D A;  4GTX A;  3DYC A;  3WAW A;  4CXU A;  3UN5 A;  1KH4 A;  1EW9 A;  4YR1 A;  5C66 A;  4ZG6 A;  3WBH A;  2QZU A;  3M8Y A;  1EW8 A;  3LXQ A;  3NVL A;  4FDJ A;  4KAV A;  5L0B A;  3SZY A;  3OT9 A;  4NWJ A;  4CXS A;  1ELZ A;  2IUC A;  3BDF A;  4ZG7 A;  1EJJ A;  1HQA A;  1ZEB A;  2VQR A;  3M8W A;  4N7T A;  2W8S A;  3IDD A;  4LRF A;  4QAX A;  4KM4 A;  4LR8 A;  3TWZ A;  5LIA A;  5IJS A;  2ZKT A;  2GLQ A;  1K7H A;  5L0E A;  1SHQ A;  1Y7A A;  3M7V A;  4MY4 A;  5AJ9 A;  1N2L A;  1KH7 A;  5IJQ A;  4UOO A;  4LR7 A;  3DPC A;  2GSO A;  1P49 A;  2W5S A;  4LQY A;  4LR2 A;  1ANJ A;  4KJG A;  1HDH A;  3WAX A;  1ANI A;  5EGH A;  2X98 A;  3TX0 A;  3NKP A;  1ZED A;  3IGY B;  2XR9 A;  5LQQ A;  4MHX A;  1KHJ A;  2W5W A;  2W5T A;  4NWX A;  1KHN A;  1E33 P;  3KD8 A;  4UPK A;  2W8D A;  1AUK A;  4CYR A;  1ALI A;  4LRA A;  4KJD A;  1ED8 A;  3ED4 A;  4FDI A;  1AJB A;  2D1G A;  2W5X A;  1EI6 A;  2XRG A;  3M8Z A;  3UO0 A; 
#chains in the Genus database with same CATH homology
 1KH5 A;  2ANH A;  5LRM A;  3WAV A;  4LR9 A;  3SZZ A;  3BDG B;  3B5Q A;  4LRD A;  4ZG9 A;  1ZEF A;  1KH9 A;  3MK1 A;  3UN3 A;  2GSU A;  4GTW A;  1N2K A;  4TN0 A;  4UOR A;  1ALH A;  1O99 A;  3TG0 A;  4CXK A;  4UPL A;  1E2S P;  4LRB A;  5HRT A;  1FSU A;  1E1Z P;  4GTY A;  1ELX A;  2W5Q A;  2IFY A;  1EW2 A;  3MK2 A;  5INH A;  4KAY A;  4MIV A;  3NKN A;  3T02 A;  3BDG A;  3WAY A;  3MK0 A;  2W5R A;  1KHK A;  1HJK A;  5GRR A;  4GTZ A;  1ED9 A;  2GA3 A;  2GSN A;  2W5V A;  3BDH A;  3NKQ A;  3T00 A;  4UPI A;  3CMR A;  3T01 A;  3UN2 A;  5DLV A;  1AJD A;  1AJA A;  1SHN A;  1ELY A;  1URB A;  5TJ3 A;  3A52 A;  4CYS A;  1O98 A;  1ALK A;  5DLW A;  5EGE A;  4LRE A;  5L0K A;  1B8J A;  2IUC B;  2G9Y A;  1EQJ A;  5LRN A;  4UOP A;  4UPH A;  4B56 A;  1Y6V A;  3NKM A;  3Q3Q A;  5GOV A;  1URA A;  1AJC A;  1KHL A;  2RH6 A;  3IGZ B;  1E3C P;  5K4P A;  3UNY A;  1ALJ A;  4ZGA A;  4LRC A;  3NKR A;  5KXA A;  5DLT A;  3NKO A;  3E2D A;  4GTX A;  3DYC A;  3WAW A;  4CXU A;  3UN5 A;  1KH4 A;  1EW9 A;  4YR1 A;  5C66 A;  4ZG6 A;  3WBH A;  2QZU A;  3M8Y A;  1EW8 A;  3LXQ A;  3NVL A;  4FDJ A;  4KAV A;  5L0B A;  3SZY A;  3OT9 A;  4NWJ A;  4CXS A;  1ELZ A;  2IUC A;  3BDF A;  4ZG7 A;  1EJJ A;  1HQA A;  1ZEB A;  2VQR A;  3M8W A;  4N7T A;  2W8S A;  3IDD A;  4LRF A;  4QAX A;  4KM4 A;  4LR8 A;  3TWZ A;  5LIA A;  5IJS A;  2ZKT A;  2GLQ A;  1K7H A;  5L0E A;  1SHQ A;  1Y7A A;  3M7V A;  4MY4 A;  5AJ9 A;  1N2L A;  1KH7 A;  5IJQ A;  4UOO A;  4LR7 A;  3DPC A;  2GSO A;  1P49 A;  2W5S A;  4LQY A;  4LR2 A;  1ANJ A;  4KJG A;  1HDH A;  3WAX A;  1ANI A;  5EGH A;  2X98 A;  3TX0 A;  3NKP A;  1ZED A;  3IGY B;  2XR9 A;  5LQQ A;  4MHX A;  1KHJ A;  2W5W A;  2W5T A;  4NWX A;  1KHN A;  1E33 P;  3KD8 A;  4UPK A;  2W8D A;  1AUK A;  4CYR A;  1ALI A;  4LRA A;  4KJD A;  1ED8 A;  3ED4 A;  4FDI A;  1AJB A;  2D1G A;  2W5X A;  1EI6 A;  2XRG A;  3M8Z A;  3UO0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...