1URAA

Alkaline phosphatase (d51zn)
Total Genus 160
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
160
Knots found
sequence length
446
structure length
446
Chain Sequence
MPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGNGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Alkaline phosphatase
molecule keywords ALKALINE PHOSPHATASE
publication title Kinetic and structural consequences of replacing the aspartate bridge by asparagine in the catalytic metal triad of Escherichia coli alkaline phosphatase.
pubmed doi rcsb
source organism Escherichia coli
total genus 160
structure length 446
sequence length 446
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1996-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1uraA00
1ZEFA 1SHQA 3TG0A 1AJCA 5L0BA 2W8SA 1EJJA 1O99A 5C66A 3T01A 4LR9A 3B5QA 3IGYB 2ANHA 1E3CP 1Y6VA 5DLWA 3DPCA 3NKPA 1EW2A 2W5RA 2GSOA 4QAXA 5LRNA 3M8ZA 2G9YA 4ZG6A 5AJ9A 5GOVA 1KHNA 3M7VA 1KH5A 1P49A 3IDDA 4KJGA 3BDGB 1N2KA 1ANIA 4UOPA 1KHLA 1K7HA 4MY4A 1AUKA 5IJSA 3T02A 3UN5A 4FDIA 4LR2A 2W5TA 2GLQA 3T00A 4CXKA 4B56A 1ANJA 5K4PA 3NKMA 2IUCB 3DYCA 5LRMA 2GSNA 3MK1A 4KAVA 1KH9A 2GA3A 1SHNA 4LREA 3LXQA 5GRRA 3UN3A 4ZG9A 5HRTA 5EGHA 4GTXA 3BDHA 2GSUA 1B8JA 1E33P 4LQYA 1URBA 4N7TA 4UPHA 1URAA 4KM4A 4UPKA 3WAXA 3NKNA 4FDJA 3WAWA 1EW9A 3Q3QA 2D1GA 4GTZA 1AJBA 1EW8A 3UNYA 4ZG7A 2IUCA 4MIVA 1HQAA 1AJAA 1HDHA 4TN0A 3WAYA 3BDFA 2QZUA 2W5WA 1ZEDA 3M8WA 5L0EA 5LQQA 1HJKA 1KH4A 1E1ZP 2VQRA 1ALJA 2ZKTA 3BDGA 1AJDA 4LRAA 1KHKA 4UORA 3IGZB 1O98A 3KD8A 4LRCA 5TJ3A 4LRBA 2X98A 4CYRA 3E2DA 4LR7A 5L0KA 1KH7A 4GTWA 4CXSA 2W5QA 5DLTA 5LIAA 3NKRA 3TWZA 2XRGA 5DLVA 1ELZA 4UPIA 2IFYA 2W5XA 3WBHA 3NVLA 3CMRA 3OT9A 1ALIA 4LR8A 2W5VA 4YR1A 5KXAA 4ZGAA 4CXUA 4NWXA 3M8YA 3WAVA 5INHA 1ED8A 1FSUA 3MK2A 4GTYA 4NWJA 4UOOA 1ALHA 1EQJA 1ELYA 3A52A 3UN2A 1Y7AA 5IJQA 3TX0A 1ELXA 2XR9A 4LRDA 1ZEBA 1ALKA 1EI6A 5EGEA 3SZYA 1ED9A 3MK0A 2W5SA 2W8DA 3NKQA 4KAYA 4KJDA 4LRFA 4MHXA 3UO0A 3ED4A 3NKOA 3SZZA 1N2LA 4CYSA 4UPLA 1E2SP 1KHJA 2RH6A
chains in the Genus database with same CATH superfamily
1ZEFA 1SHQA 3TG0A 1AJCA 5L0BA 2W8SA 1EJJA 1O99A 5C66A 3T01A 4LR9A 3B5QA 3IGYB 2ANHA 1E3CP 1Y6VA 5DLWA 3DPCA 3NKPA 1EW2A 2W5RA 2GSOA 4QAXA 5LRNA 3M8ZA 2G9YA 4ZG6A 5AJ9A 5GOVA 1KHNA 3M7VA 1KH5A 1P49A 3IDDA 4KJGA 3BDGB 1N2KA 1ANIA 4UOPA 1KHLA 1K7HA 4MY4A 1AUKA 5IJSA 3T02A 3UN5A 4FDIA 4LR2A 2W5TA 2GLQA 3T00A 4CXKA 4B56A 1ANJA 5K4PA 3NKMA 2IUCB 3DYCA 5LRMA 2GSNA 3MK1A 4KAVA 1KH9A 2GA3A 1SHNA 4LREA 3LXQA 5GRRA 3UN3A 4ZG9A 5HRTA 5EGHA 4GTXA 3BDHA 2GSUA 1B8JA 1E33P 4LQYA 1URBA 4N7TA 4UPHA 1URAA 4KM4A 4UPKA 3WAXA 3NKNA 4FDJA 3WAWA 1EW9A 3Q3QA 2D1GA 4GTZA 1AJBA 1EW8A 3UNYA 4ZG7A 2IUCA 4MIVA 1HQAA 1AJAA 1HDHA 4TN0A 3WAYA 3BDFA 2QZUA 2W5WA 1ZEDA 3M8WA 5L0EA 5LQQA 1HJKA 1KH4A 1E1ZP 2VQRA 1ALJA 2ZKTA 3BDGA 1AJDA 4LRAA 1KHKA 4UORA 3IGZB 1O98A 3KD8A 4LRCA 5TJ3A 4LRBA 2X98A 4CYRA 3E2DA 4LR7A 5L0KA 1KH7A 4GTWA 4CXSA 2W5QA 5DLTA 5LIAA 3NKRA 3TWZA 2XRGA 5DLVA 1ELZA 4UPIA 2IFYA 2W5XA 3WBHA 3NVLA 3CMRA 3OT9A 1ALIA 4LR8A 2W5VA 4YR1A 5KXAA 4ZGAA 4CXUA 4NWXA 3M8YA 3WAVA 5INHA 1ED8A 1FSUA 3MK2A 4GTYA 4NWJA 4UOOA 1ALHA 1EQJA 1ELYA 3A52A 3UN2A 1Y7AA 5IJQA 3TX0A 1ELXA 2XR9A 4LRDA 1ZEBA 1ALKA 1EI6A 5EGEA 3SZYA 1ED9A 3MK0A 2W5SA 2W8DA 3NKQA 4KAYA 4KJDA 4LRFA 4MHXA 3UO0A 3ED4A 3NKOA 3SZZA 1N2LA 4CYSA 4UPLA 1E2SP 1KHJA 2RH6A
chains in the Genus database with same CATH topology
1ZEFA 1SHQA 3TG0A 1AJCA 5L0BA 2W8SA 1EJJA 1O99A 5C66A 3T01A 4LR9A 3B5QA 3IGYB 2ANHA 1E3CP 1Y6VA 5DLWA 3DPCA 3NKPA 1EW2A 2W5RA 2GSOA 4QAXA 5LRNA 3M8ZA 2G9YA 4ZG6A 5AJ9A 5GOVA 1KHNA 3M7VA 1KH5A 1P49A 3IDDA 4KJGA 3BDGB 1N2KA 1ANIA 4UOPA 1KHLA 1K7HA 4MY4A 1AUKA 5IJSA 3T02A 3UN5A 4FDIA 4LR2A 2W5TA 2GLQA 3T00A 4CXKA 4B56A 1ANJA 5K4PA 3NKMA 2IUCB 3DYCA 5LRMA 2GSNA 3MK1A 4KAVA 1KH9A 2GA3A 1SHNA 4LREA 3LXQA 5GRRA 3UN3A 4ZG9A 5HRTA 5EGHA 4GTXA 3BDHA 2GSUA 1B8JA 1E33P 4LQYA 1URBA 4N7TA 4UPHA 1URAA 4KM4A 4UPKA 3WAXA 3NKNA 4FDJA 3WAWA 1EW9A 3Q3QA 2D1GA 4GTZA 1AJBA 1EW8A 3UNYA 4ZG7A 2IUCA 4MIVA 1HQAA 1AJAA 1HDHA 4TN0A 3WAYA 3BDFA 2QZUA 2W5WA 1ZEDA 3M8WA 5L0EA 5LQQA 1HJKA 1KH4A 1E1ZP 2VQRA 1ALJA 2ZKTA 3BDGA 1AJDA 4LRAA 1KHKA 4UORA 3IGZB 1O98A 3KD8A 4LRCA 5TJ3A 4LRBA 2X98A 4CYRA 3E2DA 4LR7A 5L0KA 1KH7A 4GTWA 4CXSA 2W5QA 5DLTA 5LIAA 3NKRA 3TWZA 2XRGA 5DLVA 1ELZA 4UPIA 2IFYA 2W5XA 3WBHA 3NVLA 3CMRA 3OT9A 1ALIA 4LR8A 2W5VA 4YR1A 5KXAA 4ZGAA 4CXUA 4NWXA 3M8YA 3WAVA 5INHA 1ED8A 1FSUA 3MK2A 4GTYA 4NWJA 4UOOA 1ALHA 1EQJA 1ELYA 3A52A 3UN2A 1Y7AA 5IJQA 3TX0A 1ELXA 2XR9A 4LRDA 1ZEBA 1ALKA 1EI6A 5EGEA 3SZYA 1ED9A 3MK0A 2W5SA 2W8DA 3NKQA 4KAYA 4KJDA 4LRFA 4MHXA 3UO0A 3ED4A 3NKOA 3SZZA 1N2LA 4CYSA 4UPLA 1E2SP 1KHJA 2RH6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZEF A;  1SHQ A;  3TG0 A;  1AJC A;  5L0B A;  2W8S A;  1EJJ A;  1O99 A;  5C66 A;  3T01 A;  4LR9 A;  3B5Q A;  3IGY B;  2ANH A;  1E3C P;  1Y6V A;  5DLW A;  3DPC A;  3NKP A;  1EW2 A;  2W5R A;  2GSO A;  4QAX A;  5LRN A;  3M8Z A;  2G9Y A;  4ZG6 A;  5AJ9 A;  5GOV A;  1KHN A;  3M7V A;  1KH5 A;  1P49 A;  3IDD A;  4KJG A;  3BDG B;  1N2K A;  1ANI A;  4UOP A;  1KHL A;  1K7H A;  4MY4 A;  1AUK A;  5IJS A;  3T02 A;  3UN5 A;  4FDI A;  4LR2 A;  2W5T A;  2GLQ A;  3T00 A;  4CXK A;  4B56 A;  1ANJ A;  5K4P A;  3NKM A;  2IUC B;  3DYC A;  5LRM A;  2GSN A;  3MK1 A;  4KAV A;  1KH9 A;  2GA3 A;  1SHN A;  4LRE A;  3LXQ A;  5GRR A;  3UN3 A;  4ZG9 A;  5HRT A;  5EGH A;  4GTX A;  3BDH A;  2GSU A;  1B8J A;  1E33 P;  4LQY A;  1URB A;  4N7T A;  4UPH A;  1URA A;  4KM4 A;  4UPK A;  3WAX A;  3NKN A;  4FDJ A;  3WAW A;  1EW9 A;  3Q3Q A;  2D1G A;  4GTZ A;  1AJB A;  1EW8 A;  3UNY A;  4ZG7 A;  2IUC A;  4MIV A;  1HQA A;  1AJA A;  1HDH A;  4TN0 A;  3WAY A;  3BDF A;  2QZU A;  2W5W A;  1ZED A;  3M8W A;  5L0E A;  5LQQ A;  1HJK A;  1KH4 A;  1E1Z P;  2VQR A;  1ALJ A;  2ZKT A;  3BDG A;  1AJD A;  4LRA A;  1KHK A;  4UOR A;  3IGZ B;  1O98 A;  3KD8 A;  4LRC A;  5TJ3 A;  4LRB A;  2X98 A;  4CYR A;  3E2D A;  4LR7 A;  5L0K A;  1KH7 A;  4GTW A;  4CXS A;  2W5Q A;  5DLT A;  5LIA A;  3NKR A;  3TWZ A;  2XRG A;  5DLV A;  1ELZ A;  4UPI A;  2IFY A;  2W5X A;  3WBH A;  3NVL A;  3CMR A;  3OT9 A;  1ALI A;  4LR8 A;  2W5V A;  4YR1 A;  5KXA A;  4ZGA A;  4CXU A;  4NWX A;  3M8Y A;  3WAV A;  5INH A;  1ED8 A;  1FSU A;  3MK2 A;  4GTY A;  4NWJ A;  4UOO A;  1ALH A;  1EQJ A;  1ELY A;  3A52 A;  3UN2 A;  1Y7A A;  5IJQ A;  3TX0 A;  1ELX A;  2XR9 A;  4LRD A;  1ZEB A;  1ALK A;  1EI6 A;  5EGE A;  3SZY A;  1ED9 A;  3MK0 A;  2W5S A;  2W8D A;  3NKQ A;  4KAY A;  4KJD A;  4LRF A;  4MHX A;  3UO0 A;  3ED4 A;  3NKO A;  3SZZ A;  1N2L A;  4CYS A;  4UPL A;  1E2S P;  1KHJ A;  2RH6 A; 
#chains in the Genus database with same CATH topology
 1ZEF A;  1SHQ A;  3TG0 A;  1AJC A;  5L0B A;  2W8S A;  1EJJ A;  1O99 A;  5C66 A;  3T01 A;  4LR9 A;  3B5Q A;  3IGY B;  2ANH A;  1E3C P;  1Y6V A;  5DLW A;  3DPC A;  3NKP A;  1EW2 A;  2W5R A;  2GSO A;  4QAX A;  5LRN A;  3M8Z A;  2G9Y A;  4ZG6 A;  5AJ9 A;  5GOV A;  1KHN A;  3M7V A;  1KH5 A;  1P49 A;  3IDD A;  4KJG A;  3BDG B;  1N2K A;  1ANI A;  4UOP A;  1KHL A;  1K7H A;  4MY4 A;  1AUK A;  5IJS A;  3T02 A;  3UN5 A;  4FDI A;  4LR2 A;  2W5T A;  2GLQ A;  3T00 A;  4CXK A;  4B56 A;  1ANJ A;  5K4P A;  3NKM A;  2IUC B;  3DYC A;  5LRM A;  2GSN A;  3MK1 A;  4KAV A;  1KH9 A;  2GA3 A;  1SHN A;  4LRE A;  3LXQ A;  5GRR A;  3UN3 A;  4ZG9 A;  5HRT A;  5EGH A;  4GTX A;  3BDH A;  2GSU A;  1B8J A;  1E33 P;  4LQY A;  1URB A;  4N7T A;  4UPH A;  1URA A;  4KM4 A;  4UPK A;  3WAX A;  3NKN A;  4FDJ A;  3WAW A;  1EW9 A;  3Q3Q A;  2D1G A;  4GTZ A;  1AJB A;  1EW8 A;  3UNY A;  4ZG7 A;  2IUC A;  4MIV A;  1HQA A;  1AJA A;  1HDH A;  4TN0 A;  3WAY A;  3BDF A;  2QZU A;  2W5W A;  1ZED A;  3M8W A;  5L0E A;  5LQQ A;  1HJK A;  1KH4 A;  1E1Z P;  2VQR A;  1ALJ A;  2ZKT A;  3BDG A;  1AJD A;  4LRA A;  1KHK A;  4UOR A;  3IGZ B;  1O98 A;  3KD8 A;  4LRC A;  5TJ3 A;  4LRB A;  2X98 A;  4CYR A;  3E2D A;  4LR7 A;  5L0K A;  1KH7 A;  4GTW A;  4CXS A;  2W5Q A;  5DLT A;  5LIA A;  3NKR A;  3TWZ A;  2XRG A;  5DLV A;  1ELZ A;  4UPI A;  2IFY A;  2W5X A;  3WBH A;  3NVL A;  3CMR A;  3OT9 A;  1ALI A;  4LR8 A;  2W5V A;  4YR1 A;  5KXA A;  4ZGA A;  4CXU A;  4NWX A;  3M8Y A;  3WAV A;  5INH A;  1ED8 A;  1FSU A;  3MK2 A;  4GTY A;  4NWJ A;  4UOO A;  1ALH A;  1EQJ A;  1ELY A;  3A52 A;  3UN2 A;  1Y7A A;  5IJQ A;  3TX0 A;  1ELX A;  2XR9 A;  4LRD A;  1ZEB A;  1ALK A;  1EI6 A;  5EGE A;  3SZY A;  1ED9 A;  3MK0 A;  2W5S A;  2W8D A;  3NKQ A;  4KAY A;  4KJD A;  4LRF A;  4MHX A;  3UO0 A;  3ED4 A;  3NKO A;  3SZZ A;  1N2L A;  4CYS A;  4UPL A;  1E2S P;  1KHJ A;  2RH6 A; 
#chains in the Genus database with same CATH homology
 1ZEF A;  1SHQ A;  3TG0 A;  1AJC A;  5L0B A;  2W8S A;  1EJJ A;  1O99 A;  5C66 A;  3T01 A;  4LR9 A;  3B5Q A;  3IGY B;  2ANH A;  1E3C P;  1Y6V A;  5DLW A;  3DPC A;  3NKP A;  1EW2 A;  2W5R A;  2GSO A;  4QAX A;  5LRN A;  3M8Z A;  2G9Y A;  4ZG6 A;  5AJ9 A;  5GOV A;  1KHN A;  3M7V A;  1KH5 A;  1P49 A;  3IDD A;  4KJG A;  3BDG B;  1N2K A;  1ANI A;  4UOP A;  1KHL A;  1K7H A;  4MY4 A;  1AUK A;  5IJS A;  3T02 A;  3UN5 A;  4FDI A;  4LR2 A;  2W5T A;  2GLQ A;  3T00 A;  4CXK A;  4B56 A;  1ANJ A;  5K4P A;  3NKM A;  2IUC B;  3DYC A;  5LRM A;  2GSN A;  3MK1 A;  4KAV A;  1KH9 A;  2GA3 A;  1SHN A;  4LRE A;  3LXQ A;  5GRR A;  3UN3 A;  4ZG9 A;  5HRT A;  5EGH A;  4GTX A;  3BDH A;  2GSU A;  1B8J A;  1E33 P;  4LQY A;  1URB A;  4N7T A;  4UPH A;  1URA A;  4KM4 A;  4UPK A;  3WAX A;  3NKN A;  4FDJ A;  3WAW A;  1EW9 A;  3Q3Q A;  2D1G A;  4GTZ A;  1AJB A;  1EW8 A;  3UNY A;  4ZG7 A;  2IUC A;  4MIV A;  1HQA A;  1AJA A;  1HDH A;  4TN0 A;  3WAY A;  3BDF A;  2QZU A;  2W5W A;  1ZED A;  3M8W A;  5L0E A;  5LQQ A;  1HJK A;  1KH4 A;  1E1Z P;  2VQR A;  1ALJ A;  2ZKT A;  3BDG A;  1AJD A;  4LRA A;  1KHK A;  4UOR A;  3IGZ B;  1O98 A;  3KD8 A;  4LRC A;  5TJ3 A;  4LRB A;  2X98 A;  4CYR A;  3E2D A;  4LR7 A;  5L0K A;  1KH7 A;  4GTW A;  4CXS A;  2W5Q A;  5DLT A;  5LIA A;  3NKR A;  3TWZ A;  2XRG A;  5DLV A;  1ELZ A;  4UPI A;  2IFY A;  2W5X A;  3WBH A;  3NVL A;  3CMR A;  3OT9 A;  1ALI A;  4LR8 A;  2W5V A;  4YR1 A;  5KXA A;  4ZGA A;  4CXU A;  4NWX A;  3M8Y A;  3WAV A;  5INH A;  1ED8 A;  1FSU A;  3MK2 A;  4GTY A;  4NWJ A;  4UOO A;  1ALH A;  1EQJ A;  1ELY A;  3A52 A;  3UN2 A;  1Y7A A;  5IJQ A;  3TX0 A;  1ELX A;  2XR9 A;  4LRD A;  1ZEB A;  1ALK A;  1EI6 A;  5EGE A;  3SZY A;  1ED9 A;  3MK0 A;  2W5S A;  2W8D A;  3NKQ A;  4KAY A;  4KJD A;  4LRF A;  4MHX A;  3UO0 A;  3ED4 A;  3NKO A;  3SZZ A;  1N2L A;  4CYS A;  4UPL A;  1E2S P;  1KHJ A;  2RH6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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