3NVLA

Crystal structure of phosphoglycerate mutase from trypanosoma brucei
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
Knots found
sequence length
549
structure length
549
Chain Sequence
LTLAAHKTLPRRKLVLVVLDGVGIGPRDEYDAVHVAKTPLMDALFNDPKHFRSICAHGTAVGLPTDADMGNSEVGHNALGAGRVVLQGASLVDDALESGEIFTSEGYRYLHGAFSQPGRTLHLIGLLSDGGVHSRDNQVYQILKHAGANGAKRIRVHALYDGRDVPDKTSFKFTDELEEVLAKLREGGCDARIASGGGRMFVTMDRYEADWSIVERGWRAQVLGEGRAFKSAREALTKFREEDANISDQYYPPFVIAGDDGRPIGTIEDGDAVLCFNFRGDRVIEMSRAFEEEEFDKFNRVRLPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRTSEEYLIGSGCNIFALSETQKFGHVTYFWNGNRSGKLSEERETFCEIPSDRVQFNQKPLMKSKEITDAAVDAIKSGKYDMIRINYPNGDMVGHTGDLKATITSLEAVDQSLQRLKEAVDSVNGVFLITADHGNSDDMVQRDKKGKPVRDAEGNLMPLTSHTLAPVPVFIGGAGLDPRVQMRTDLPRAGLANVTATFINLMGFEAPSDYEPSLIEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Isomerase
molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
publication title Crystal structure of phosphoglycerate mutase from Trypanosoma brucei.
pubmed doi rcsb
source organism Trypanosoma brucei
total genus 199
structure length 549
sequence length 549
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2010-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3nvlA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 3nvlA02
1ANIA 3NKRA 1ZEBA 3MK2A 1N2KA 2QZUA 5HRTA 5DLTA 4LR9A 5IJQA 1KHNA 3MK1A 5DLWA 3UN3A 4UPLA 1KHJA 2VQRA 4KAVA 3UNYA 3LXQA 5L0BA 1P49A 2GA3A 1URBA 4FDJA 4NWJA 3KD8A 3WBHA 4UOPA 1AJBA 2W5XA 1KH7A 4LR2A 4KM4A 2XRGA 3CMRA 2GSNA 1EI6A 1O98A 4MHXA 1AJDA 2GLQA 4LRCA 3BDGB 1ED8A 1O99A 5GRRA 4LRFA 5K4PA 2IUCB 1KHLA 4FDIA 4UORA 4GTXA 1ALHA 1Y6VA 3B5QA 3NKPA 3WAXA 3IGZB 5AJ9A 1URAA 2W8SA 4LR7A 4YR1A 2W8DA 3NKNA 5LIAA 2W5QA 2IFYA 4UPIA 3T00A 5EGHA 5IJSA 3BDHA 3OT9A 3NKOA 1FSUA 4TN0A 3M7VA 3WAYA 1B8JA 4ZG6A 1EQJA 2RH6A 3NVLA 1SHQA 1ALIA 4UPHA 4B56A 1E1ZP 2ANHA 2GSOA 3T02A 2W5WA 4UPKA 4KJDA 2W5TA 4CXUA 1ALJA 5L0EA 1HQAA 2W5RA 2XR9A 3Q3QA 2ZKTA 4MIVA 3UN5A 3UN2A 3MK0A 3DPCA 3M8WA 4NWXA 3IDDA 2G9YA 2D1GA 1E33P 3WAWA 3TG0A 4CXKA 4ZG9A 1SHNA 1ED9A 4GTZA 4LR8A 4UOOA 4CYRA 3T01A 3NKQA 1HDHA 5EGEA 3IGYB 5GOVA 3SZZA 1ZEFA 1EW8A 4KAYA 1ELZA 1HJKA 4CYSA 4N7TA 1AJAA 4QAXA 1EW9A 4MY4A 1EW2A 1AJCA 2W5SA 3BDFA 2W5VA 2X98A 4GTWA 5C66A 2IUCA 1N2LA 5INHA 5LRNA 1ALKA 1K7HA 3WAVA 5LRMA 3A52A 1ELYA 4KJGA 3UO0A 3ED4A 5DLVA 5TJ3A 1KH4A 1E3CP 3TX0A 1AUKA 1KH9A 1Y7AA 1KH5A 1EJJA 3SZYA 4LRBA 2GSUA 3DYCA 3E2DA 3M8YA 1ZEDA 3TWZA 4GTYA 5KXAA 1ELXA 4LQYA 4ZGAA 1ANJA 4LREA 1KHKA 4ZG7A 1E2SP 3M8ZA 5LQQA 4CXSA 4LRDA 5L0KA 3BDGA 3NKMA 4LRAA
chains in the Genus database with same CATH superfamily
1ANIA 3NKRA 1ZEBA 3MK2A 1N2KA 2QZUA 5HRTA 5DLTA 4LR9A 5IJQA 1KHNA 3MK1A 5DLWA 3UN3A 4UPLA 1KHJA 2VQRA 4KAVA 3UNYA 3LXQA 5L0BA 1P49A 2GA3A 1URBA 4FDJA 4NWJA 3KD8A 3WBHA 4UOPA 1AJBA 2W5XA 1KH7A 4LR2A 4KM4A 2XRGA 3CMRA 2GSNA 1EI6A 1O98A 4MHXA 1AJDA 2GLQA 4LRCA 3BDGB 1ED8A 1O99A 5GRRA 4LRFA 5K4PA 2IUCB 1KHLA 4FDIA 4UORA 4GTXA 1ALHA 1Y6VA 3B5QA 3NKPA 3WAXA 3IGZB 5AJ9A 1URAA 2W8SA 4LR7A 4YR1A 2W8DA 3NKNA 5LIAA 2W5QA 2IFYA 4UPIA 3T00A 5EGHA 5IJSA 3BDHA 3OT9A 3NKOA 1FSUA 4TN0A 3M7VA 3WAYA 1B8JA 4ZG6A 1EQJA 2RH6A 3NVLA 1SHQA 1ALIA 4UPHA 4B56A 1E1ZP 2ANHA 2GSOA 3T02A 2W5WA 4UPKA 4KJDA 2W5TA 4CXUA 1ALJA 5L0EA 1HQAA 2W5RA 2XR9A 3Q3QA 2ZKTA 4MIVA 3UN5A 3UN2A 3MK0A 3DPCA 3M8WA 4NWXA 3IDDA 2G9YA 2D1GA 1E33P 3WAWA 3TG0A 4CXKA 4ZG9A 1SHNA 1ED9A 4GTZA 4LR8A 4UOOA 4CYRA 3T01A 3NKQA 1HDHA 5EGEA 3IGYB 5GOVA 3SZZA 1ZEFA 1EW8A 4KAYA 1ELZA 1HJKA 4CYSA 4N7TA 1AJAA 4QAXA 1EW9A 4MY4A 1EW2A 1AJCA 2W5SA 3BDFA 2W5VA 2X98A 4GTWA 5C66A 2IUCA 1N2LA 5INHA 5LRNA 1ALKA 1K7HA 3WAVA 5LRMA 3A52A 1ELYA 4KJGA 3UO0A 3ED4A 5DLVA 5TJ3A 1KH4A 1E3CP 3TX0A 1AUKA 1KH9A 1Y7AA 1KH5A 1EJJA 3SZYA 4LRBA 2GSUA 3DYCA 3E2DA 3M8YA 1ZEDA 3TWZA 4GTYA 5KXAA 1ELXA 4LQYA 4ZGAA 1ANJA 4LREA 1KHKA 4ZG7A 1E2SP 3M8ZA 5LQQA 4CXSA 4LRDA 5L0KA 3BDGA 3NKMA 4LRAA
chains in the Genus database with same CATH topology
1ANIA 3NKRA 1ZEBA 3MK2A 1N2KA 2QZUA 5HRTA 5DLTA 4LR9A 5IJQA 1KHNA 3MK1A 5DLWA 3UN3A 4UPLA 1KHJA 2VQRA 4KAVA 3UNYA 3LXQA 5L0BA 1P49A 2GA3A 1URBA 4FDJA 4NWJA 3KD8A 3WBHA 4UOPA 1AJBA 2W5XA 1KH7A 4LR2A 4KM4A 2XRGA 3CMRA 2GSNA 1EI6A 1O98A 4MHXA 1AJDA 2GLQA 4LRCA 3BDGB 1ED8A 1O99A 5GRRA 4LRFA 5K4PA 2IUCB 1KHLA 4FDIA 4UORA 4GTXA 1ALHA 1Y6VA 3B5QA 3NKPA 3WAXA 3IGZB 5AJ9A 1URAA 2W8SA 4LR7A 4YR1A 2W8DA 3NKNA 5LIAA 2W5QA 2IFYA 4UPIA 3T00A 5EGHA 5IJSA 3BDHA 3OT9A 3NKOA 1FSUA 4TN0A 3M7VA 3WAYA 1B8JA 4ZG6A 1EQJA 2RH6A 3NVLA 1SHQA 1ALIA 4UPHA 4B56A 1E1ZP 2ANHA 2GSOA 3T02A 2W5WA 4UPKA 4KJDA 2W5TA 4CXUA 1ALJA 5L0EA 1HQAA 2W5RA 2XR9A 3Q3QA 2ZKTA 4MIVA 3UN5A 3UN2A 3MK0A 3DPCA 3M8WA 4NWXA 3IDDA 2G9YA 2D1GA 1E33P 3WAWA 3TG0A 4CXKA 4ZG9A 1SHNA 1ED9A 4GTZA 4LR8A 4UOOA 4CYRA 3T01A 3NKQA 1HDHA 5EGEA 3IGYB 5GOVA 3SZZA 1ZEFA 1EW8A 4KAYA 1ELZA 1HJKA 4CYSA 4N7TA 1AJAA 4QAXA 1EW9A 4MY4A 1EW2A 1AJCA 2W5SA 3BDFA 2W5VA 2X98A 4GTWA 5C66A 2IUCA 1N2LA 5INHA 5LRNA 1ALKA 1K7HA 3WAVA 5LRMA 3A52A 1ELYA 4KJGA 3UO0A 3ED4A 5DLVA 5TJ3A 1KH4A 1E3CP 3TX0A 1AUKA 1KH9A 1Y7AA 1KH5A 1EJJA 3SZYA 4LRBA 2GSUA 3DYCA 3E2DA 3M8YA 1ZEDA 3TWZA 4GTYA 5KXAA 1ELXA 4LQYA 4ZGAA 1ANJA 4LREA 1KHKA 4ZG7A 1E2SP 3M8ZA 5LQQA 4CXSA 4LRDA 5L0KA 3BDGA 3NKMA 4LRAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ANI A;  3NKR A;  1ZEB A;  3MK2 A;  1N2K A;  2QZU A;  5HRT A;  5DLT A;  4LR9 A;  5IJQ A;  1KHN A;  3MK1 A;  5DLW A;  3UN3 A;  4UPL A;  1KHJ A;  2VQR A;  4KAV A;  3UNY A;  3LXQ A;  5L0B A;  1P49 A;  2GA3 A;  1URB A;  4FDJ A;  4NWJ A;  3KD8 A;  3WBH A;  4UOP A;  1AJB A;  2W5X A;  1KH7 A;  4LR2 A;  4KM4 A;  2XRG A;  3CMR A;  2GSN A;  1EI6 A;  1O98 A;  4MHX A;  1AJD A;  2GLQ A;  4LRC A;  3BDG B;  1ED8 A;  1O99 A;  5GRR A;  4LRF A;  5K4P A;  2IUC B;  1KHL A;  4FDI A;  4UOR A;  4GTX A;  1ALH A;  1Y6V A;  3B5Q A;  3NKP A;  3WAX A;  3IGZ B;  5AJ9 A;  1URA A;  2W8S A;  4LR7 A;  4YR1 A;  2W8D A;  3NKN A;  5LIA A;  2W5Q A;  2IFY A;  4UPI A;  3T00 A;  5EGH A;  5IJS A;  3BDH A;  3OT9 A;  3NKO A;  1FSU A;  4TN0 A;  3M7V A;  3WAY A;  1B8J A;  4ZG6 A;  1EQJ A;  2RH6 A;  3NVL A;  1SHQ A;  1ALI A;  4UPH A;  4B56 A;  1E1Z P;  2ANH A;  2GSO A;  3T02 A;  2W5W A;  4UPK A;  4KJD A;  2W5T A;  4CXU A;  1ALJ A;  5L0E A;  1HQA A;  2W5R A;  2XR9 A;  3Q3Q A;  2ZKT A;  4MIV A;  3UN5 A;  3UN2 A;  3MK0 A;  3DPC A;  3M8W A;  4NWX A;  3IDD A;  2G9Y A;  2D1G A;  1E33 P;  3WAW A;  3TG0 A;  4CXK A;  4ZG9 A;  1SHN A;  1ED9 A;  4GTZ A;  4LR8 A;  4UOO A;  4CYR A;  3T01 A;  3NKQ A;  1HDH A;  5EGE A;  3IGY B;  5GOV A;  3SZZ A;  1ZEF A;  1EW8 A;  4KAY A;  1ELZ A;  1HJK A;  4CYS A;  4N7T A;  1AJA A;  4QAX A;  1EW9 A;  4MY4 A;  1EW2 A;  1AJC A;  2W5S A;  3BDF A;  2W5V A;  2X98 A;  4GTW A;  5C66 A;  2IUC A;  1N2L A;  5INH A;  5LRN A;  1ALK A;  1K7H A;  3WAV A;  5LRM A;  3A52 A;  1ELY A;  4KJG A;  3UO0 A;  3ED4 A;  5DLV A;  5TJ3 A;  1KH4 A;  1E3C P;  3TX0 A;  1AUK A;  1KH9 A;  1Y7A A;  1KH5 A;  1EJJ A;  3SZY A;  4LRB A;  2GSU A;  3DYC A;  3E2D A;  3M8Y A;  1ZED A;  3TWZ A;  4GTY A;  5KXA A;  1ELX A;  4LQY A;  4ZGA A;  1ANJ A;  4LRE A;  1KHK A;  4ZG7 A;  1E2S P;  3M8Z A;  5LQQ A;  4CXS A;  4LRD A;  5L0K A;  3BDG A;  3NKM A;  4LRA A; 
#chains in the Genus database with same CATH topology
 1ANI A;  3NKR A;  1ZEB A;  3MK2 A;  1N2K A;  2QZU A;  5HRT A;  5DLT A;  4LR9 A;  5IJQ A;  1KHN A;  3MK1 A;  5DLW A;  3UN3 A;  4UPL A;  1KHJ A;  2VQR A;  4KAV A;  3UNY A;  3LXQ A;  5L0B A;  1P49 A;  2GA3 A;  1URB A;  4FDJ A;  4NWJ A;  3KD8 A;  3WBH A;  4UOP A;  1AJB A;  2W5X A;  1KH7 A;  4LR2 A;  4KM4 A;  2XRG A;  3CMR A;  2GSN A;  1EI6 A;  1O98 A;  4MHX A;  1AJD A;  2GLQ A;  4LRC A;  3BDG B;  1ED8 A;  1O99 A;  5GRR A;  4LRF A;  5K4P A;  2IUC B;  1KHL A;  4FDI A;  4UOR A;  4GTX A;  1ALH A;  1Y6V A;  3B5Q A;  3NKP A;  3WAX A;  3IGZ B;  5AJ9 A;  1URA A;  2W8S A;  4LR7 A;  4YR1 A;  2W8D A;  3NKN A;  5LIA A;  2W5Q A;  2IFY A;  4UPI A;  3T00 A;  5EGH A;  5IJS A;  3BDH A;  3OT9 A;  3NKO A;  1FSU A;  4TN0 A;  3M7V A;  3WAY A;  1B8J A;  4ZG6 A;  1EQJ A;  2RH6 A;  3NVL A;  1SHQ A;  1ALI A;  4UPH A;  4B56 A;  1E1Z P;  2ANH A;  2GSO A;  3T02 A;  2W5W A;  4UPK A;  4KJD A;  2W5T A;  4CXU A;  1ALJ A;  5L0E A;  1HQA A;  2W5R A;  2XR9 A;  3Q3Q A;  2ZKT A;  4MIV A;  3UN5 A;  3UN2 A;  3MK0 A;  3DPC A;  3M8W A;  4NWX A;  3IDD A;  2G9Y A;  2D1G A;  1E33 P;  3WAW A;  3TG0 A;  4CXK A;  4ZG9 A;  1SHN A;  1ED9 A;  4GTZ A;  4LR8 A;  4UOO A;  4CYR A;  3T01 A;  3NKQ A;  1HDH A;  5EGE A;  3IGY B;  5GOV A;  3SZZ A;  1ZEF A;  1EW8 A;  4KAY A;  1ELZ A;  1HJK A;  4CYS A;  4N7T A;  1AJA A;  4QAX A;  1EW9 A;  4MY4 A;  1EW2 A;  1AJC A;  2W5S A;  3BDF A;  2W5V A;  2X98 A;  4GTW A;  5C66 A;  2IUC A;  1N2L A;  5INH A;  5LRN A;  1ALK A;  1K7H A;  3WAV A;  5LRM A;  3A52 A;  1ELY A;  4KJG A;  3UO0 A;  3ED4 A;  5DLV A;  5TJ3 A;  1KH4 A;  1E3C P;  3TX0 A;  1AUK A;  1KH9 A;  1Y7A A;  1KH5 A;  1EJJ A;  3SZY A;  4LRB A;  2GSU A;  3DYC A;  3E2D A;  3M8Y A;  1ZED A;  3TWZ A;  4GTY A;  5KXA A;  1ELX A;  4LQY A;  4ZGA A;  1ANJ A;  4LRE A;  1KHK A;  4ZG7 A;  1E2S P;  3M8Z A;  5LQQ A;  4CXS A;  4LRD A;  5L0K A;  3BDG A;  3NKM A;  4LRA A; 
#chains in the Genus database with same CATH homology
 1ANI A;  3NKR A;  1ZEB A;  3MK2 A;  1N2K A;  2QZU A;  5HRT A;  5DLT A;  4LR9 A;  5IJQ A;  1KHN A;  3MK1 A;  5DLW A;  3UN3 A;  4UPL A;  1KHJ A;  2VQR A;  4KAV A;  3UNY A;  3LXQ A;  5L0B A;  1P49 A;  2GA3 A;  1URB A;  4FDJ A;  4NWJ A;  3KD8 A;  3WBH A;  4UOP A;  1AJB A;  2W5X A;  1KH7 A;  4LR2 A;  4KM4 A;  2XRG A;  3CMR A;  2GSN A;  1EI6 A;  1O98 A;  4MHX A;  1AJD A;  2GLQ A;  4LRC A;  3BDG B;  1ED8 A;  1O99 A;  5GRR A;  4LRF A;  5K4P A;  2IUC B;  1KHL A;  4FDI A;  4UOR A;  4GTX A;  1ALH A;  1Y6V A;  3B5Q A;  3NKP A;  3WAX A;  3IGZ B;  5AJ9 A;  1URA A;  2W8S A;  4LR7 A;  4YR1 A;  2W8D A;  3NKN A;  5LIA A;  2W5Q A;  2IFY A;  4UPI A;  3T00 A;  5EGH A;  5IJS A;  3BDH A;  3OT9 A;  3NKO A;  1FSU A;  4TN0 A;  3M7V A;  3WAY A;  1B8J A;  4ZG6 A;  1EQJ A;  2RH6 A;  3NVL A;  1SHQ A;  1ALI A;  4UPH A;  4B56 A;  1E1Z P;  2ANH A;  2GSO A;  3T02 A;  2W5W A;  4UPK A;  4KJD A;  2W5T A;  4CXU A;  1ALJ A;  5L0E A;  1HQA A;  2W5R A;  2XR9 A;  3Q3Q A;  2ZKT A;  4MIV A;  3UN5 A;  3UN2 A;  3MK0 A;  3DPC A;  3M8W A;  4NWX A;  3IDD A;  2G9Y A;  2D1G A;  1E33 P;  3WAW A;  3TG0 A;  4CXK A;  4ZG9 A;  1SHN A;  1ED9 A;  4GTZ A;  4LR8 A;  4UOO A;  4CYR A;  3T01 A;  3NKQ A;  1HDH A;  5EGE A;  3IGY B;  5GOV A;  3SZZ A;  1ZEF A;  1EW8 A;  4KAY A;  1ELZ A;  1HJK A;  4CYS A;  4N7T A;  1AJA A;  4QAX A;  1EW9 A;  4MY4 A;  1EW2 A;  1AJC A;  2W5S A;  3BDF A;  2W5V A;  2X98 A;  4GTW A;  5C66 A;  2IUC A;  1N2L A;  5INH A;  5LRN A;  1ALK A;  1K7H A;  3WAV A;  5LRM A;  3A52 A;  1ELY A;  4KJG A;  3UO0 A;  3ED4 A;  5DLV A;  5TJ3 A;  1KH4 A;  1E3C P;  3TX0 A;  1AUK A;  1KH9 A;  1Y7A A;  1KH5 A;  1EJJ A;  3SZY A;  4LRB A;  2GSU A;  3DYC A;  3E2D A;  3M8Y A;  1ZED A;  3TWZ A;  4GTY A;  5KXA A;  1ELX A;  4LQY A;  4ZGA A;  1ANJ A;  4LRE A;  1KHK A;  4ZG7 A;  1E2S P;  3M8Z A;  5LQQ A;  4CXS A;  4LRD A;  5L0K A;  3BDG A;  3NKM A;  4LRA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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