3NVLA

Crystal structure of phosphoglycerate mutase from trypanosoma brucei
Total Genus 199
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
199
Knots found
sequence length
549
structure length
549
Chain Sequence
LTLAAHKTLPRRKLVLVVLDGVGIGPRDEYDAVHVAKTPLMDALFNDPKHFRSICAHGTAVGLPTDADMGNSEVGHNALGAGRVVLQGASLVDDALESGEIFTSEGYRYLHGAFSQPGRTLHLIGLLSDGGVHSRDNQVYQILKHAGANGAKRIRVHALYDGRDVPDKTSFKFTDELEEVLAKLREGGCDARIASGGGRMFVTMDRYEADWSIVERGWRAQVLGEGRAFKSAREALTKFREEDANISDQYYPPFVIAGDDGRPIGTIEDGDAVLCFNFRGDRVIEMSRAFEEEEFDKFNRVRLPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRTSEEYLIGSGCNIFALSETQKFGHVTYFWNGNRSGKLSEERETFCEIPSDRVQFNQKPLMKSKEITDAAVDAIKSGKYDMIRINYPNGDMVGHTGDLKATITSLEAVDQSLQRLKEAVDSVNGVFLITADHGNSDDMVQRDKKGKPVRDAEGNLMPLTSHTLAPVPVFIGGAGLDPRVQMRTDLPRAGLANVTATFINLMGFEAPSDYEPSLIEVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of phosphoglycerate mutase from Trypanosoma brucei.
pubmed doi rcsb
source organism Trypanosoma brucei
molecule tags Isomerase
molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
total genus 199
structure length 549
sequence length 549
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date 2010-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3nvlA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 3nvlA02
3UNYA 3MK0A 4QAXA 1HDHA 1KHKA 5IJQA 3UN3A 2IFYA 3UN5A 3WAYA 1ELYA 3IDDA 4MHXA 5GOVA 5INHA 1ANIA 4KAVA 4ZGAA 1KHNA 1HJKA 4LQYA 2W5RA 2IUCA 3NKRA 1AJCA 5KXAA 1KHLA 4LRFA 3T00A 2W5TA 5C66A 1ALIA 4UOPA 4GTWA 1E1ZP 1EQJA 2W5XA 1AUKA 5LIAA 4UORA 3TG0A 2VQRA 2X98A 4LRBA 3ED4A 2GSUA 4UPLA 4CYSA 5HRTA 2XR9A 3IGZB 5DLTA 1EW9A 4UPHA 3WAXA 3M7VA 1ZEDA 4MY4A 1P49A 3SZZA 3BDGA 4CXUA 4CXSA 1AJBA 4B56A 3TWZA 3WBHA 1N2KA 3IGYB 4KAYA 4LRAA 4TN0A 2ANHA 4KM4A 3T02A 4UOOA 5DLVA 4LRCA 3BDFA 1ZEFA 3M8ZA 3E2DA 1SHNA 5GRRA 1ALHA 4GTYA 2ZKTA 3UO0A 1E33P 1Y7AA 3UN2A 2RH6A 1E2SP 5LQQA 3WAWA 1ANJA 1KH9A 1URBA 1ZEBA 4LR8A 1KHJA 5TJ3A 2D1GA 1KH7A 3MK2A 1ELZA 4LR2A 1HQAA 4UPKA 1AJDA 4ZG6A 3OT9A 3KD8A 2IUCB 1SHQA 3A52A 4NWJA 2QZUA 3M8YA 1AJAA 4GTXA 1KH5A 1N2LA 3NKPA 4YR1A 3NKQA 1ALKA 2W8SA 5AJ9A 4CXKA 4LR7A 3SZYA 3LXQA 4UPIA 2GSNA 4LR9A 3T01A 2W8DA 3WAVA 4MIVA 4CYRA 3BDHA 3M8WA 1KH4A 4GTZA 5IJSA 3CMRA 2W5QA 3NVLA 4LREA 5EGEA 1EJJA 1Y6VA 3B5QA 3NKOA 1ED8A 1ALJA 1O98A 1EW2A 2XRGA 3NKMA 3MK1A 3DYCA 5DLWA 3NKNA 2GA3A 4KJDA 4ZG7A 3BDGB 4FDIA 4LRDA 1FSUA 1K7HA 5EGHA 5L0BA 5LRNA 1ELXA 1ED9A 1E3CP 5L0KA 2W5WA 3TX0A 1O99A 2W5VA 2GLQA 2W5SA 1EI6A 2GSOA 3Q3QA 2G9YA 4ZG9A 4KJGA 4N7TA 3DPCA 1URAA 5LRMA 4FDJA 1EW8A 5K4PA 5L0EA 1B8JA 4NWXA
chains in the Genus database with same CATH superfamily
3UNYA 3MK0A 4QAXA 1HDHA 1KHKA 5IJQA 3UN3A 2IFYA 3UN5A 3WAYA 1ELYA 3IDDA 4MHXA 5GOVA 5INHA 1ANIA 4KAVA 4ZGAA 1KHNA 1HJKA 4LQYA 2W5RA 2IUCA 3NKRA 1AJCA 5KXAA 1KHLA 4LRFA 3T00A 2W5TA 5C66A 1ALIA 4UOPA 4GTWA 1E1ZP 1EQJA 2W5XA 1AUKA 5LIAA 4UORA 3TG0A 2VQRA 2X98A 4LRBA 3ED4A 2GSUA 4UPLA 4CYSA 5HRTA 2XR9A 3IGZB 5DLTA 1EW9A 4UPHA 3WAXA 3M7VA 1ZEDA 4MY4A 1P49A 3SZZA 3BDGA 4CXUA 4CXSA 1AJBA 4B56A 3TWZA 3WBHA 1N2KA 3IGYB 4KAYA 4LRAA 4TN0A 2ANHA 4KM4A 3T02A 4UOOA 5DLVA 4LRCA 3BDFA 1ZEFA 3M8ZA 3E2DA 1SHNA 5GRRA 1ALHA 4GTYA 2ZKTA 3UO0A 1E33P 1Y7AA 3UN2A 2RH6A 1E2SP 5LQQA 3WAWA 1ANJA 1KH9A 1URBA 1ZEBA 4LR8A 1KHJA 5TJ3A 2D1GA 1KH7A 3MK2A 1ELZA 4LR2A 1HQAA 4UPKA 1AJDA 4ZG6A 3OT9A 3KD8A 2IUCB 1SHQA 3A52A 4NWJA 2QZUA 3M8YA 1AJAA 4GTXA 1KH5A 1N2LA 3NKPA 4YR1A 3NKQA 1ALKA 2W8SA 5AJ9A 4CXKA 4LR7A 3SZYA 3LXQA 4UPIA 2GSNA 4LR9A 3T01A 2W8DA 3WAVA 4MIVA 4CYRA 3BDHA 3M8WA 1KH4A 4GTZA 5IJSA 3CMRA 2W5QA 3NVLA 4LREA 5EGEA 1EJJA 1Y6VA 3B5QA 3NKOA 1ED8A 1ALJA 1O98A 1EW2A 2XRGA 3NKMA 3MK1A 3DYCA 5DLWA 3NKNA 2GA3A 4KJDA 4ZG7A 3BDGB 4FDIA 4LRDA 1FSUA 1K7HA 5EGHA 5L0BA 5LRNA 1ELXA 1ED9A 1E3CP 5L0KA 2W5WA 3TX0A 1O99A 2W5VA 2GLQA 2W5SA 1EI6A 2GSOA 3Q3QA 2G9YA 4ZG9A 4KJGA 4N7TA 3DPCA 1URAA 5LRMA 4FDJA 1EW8A 5K4PA 5L0EA 1B8JA 4NWXA
chains in the Genus database with same CATH topology
3UNYA 3MK0A 4QAXA 1HDHA 1KHKA 5IJQA 3UN3A 2IFYA 3UN5A 3WAYA 1ELYA 3IDDA 4MHXA 5GOVA 5INHA 1ANIA 4KAVA 4ZGAA 1KHNA 1HJKA 4LQYA 2W5RA 2IUCA 3NKRA 1AJCA 5KXAA 1KHLA 4LRFA 3T00A 2W5TA 5C66A 1ALIA 4UOPA 4GTWA 1E1ZP 1EQJA 2W5XA 1AUKA 5LIAA 4UORA 3TG0A 2VQRA 2X98A 4LRBA 3ED4A 2GSUA 4UPLA 4CYSA 5HRTA 2XR9A 3IGZB 5DLTA 1EW9A 4UPHA 3WAXA 3M7VA 1ZEDA 4MY4A 1P49A 3SZZA 3BDGA 4CXUA 4CXSA 1AJBA 4B56A 3TWZA 3WBHA 1N2KA 3IGYB 4KAYA 4LRAA 4TN0A 2ANHA 4KM4A 3T02A 4UOOA 5DLVA 4LRCA 3BDFA 1ZEFA 3M8ZA 3E2DA 1SHNA 5GRRA 1ALHA 4GTYA 2ZKTA 3UO0A 1E33P 1Y7AA 3UN2A 2RH6A 1E2SP 5LQQA 3WAWA 1ANJA 1KH9A 1URBA 1ZEBA 4LR8A 1KHJA 5TJ3A 2D1GA 1KH7A 3MK2A 1ELZA 4LR2A 1HQAA 4UPKA 1AJDA 4ZG6A 3OT9A 3KD8A 2IUCB 1SHQA 3A52A 4NWJA 2QZUA 3M8YA 1AJAA 4GTXA 1KH5A 1N2LA 3NKPA 4YR1A 3NKQA 1ALKA 2W8SA 5AJ9A 4CXKA 4LR7A 3SZYA 3LXQA 4UPIA 2GSNA 4LR9A 3T01A 2W8DA 3WAVA 4MIVA 4CYRA 3BDHA 3M8WA 1KH4A 4GTZA 5IJSA 3CMRA 2W5QA 3NVLA 4LREA 5EGEA 1EJJA 1Y6VA 3B5QA 3NKOA 1ED8A 1ALJA 1O98A 1EW2A 2XRGA 3NKMA 3MK1A 3DYCA 5DLWA 3NKNA 2GA3A 4KJDA 4ZG7A 3BDGB 4FDIA 4LRDA 1FSUA 1K7HA 5EGHA 5L0BA 5LRNA 1ELXA 1ED9A 1E3CP 5L0KA 2W5WA 3TX0A 1O99A 2W5VA 2GLQA 2W5SA 1EI6A 2GSOA 3Q3QA 2G9YA 4ZG9A 4KJGA 4N7TA 3DPCA 1URAA 5LRMA 4FDJA 1EW8A 5K4PA 5L0EA 1B8JA 4NWXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UNY A;  3MK0 A;  4QAX A;  1HDH A;  1KHK A;  5IJQ A;  3UN3 A;  2IFY A;  3UN5 A;  3WAY A;  1ELY A;  3IDD A;  4MHX A;  5GOV A;  5INH A;  1ANI A;  4KAV A;  4ZGA A;  1KHN A;  1HJK A;  4LQY A;  2W5R A;  2IUC A;  3NKR A;  1AJC A;  5KXA A;  1KHL A;  4LRF A;  3T00 A;  2W5T A;  5C66 A;  1ALI A;  4UOP A;  4GTW A;  1E1Z P;  1EQJ A;  2W5X A;  1AUK A;  5LIA A;  4UOR A;  3TG0 A;  2VQR A;  2X98 A;  4LRB A;  3ED4 A;  2GSU A;  4UPL A;  4CYS A;  5HRT A;  2XR9 A;  3IGZ B;  5DLT A;  1EW9 A;  4UPH A;  3WAX A;  3M7V A;  1ZED A;  4MY4 A;  1P49 A;  3SZZ A;  3BDG A;  4CXU A;  4CXS A;  1AJB A;  4B56 A;  3TWZ A;  3WBH A;  1N2K A;  3IGY B;  4KAY A;  4LRA A;  4TN0 A;  2ANH A;  4KM4 A;  3T02 A;  4UOO A;  5DLV A;  4LRC A;  3BDF A;  1ZEF A;  3M8Z A;  3E2D A;  1SHN A;  5GRR A;  1ALH A;  4GTY A;  2ZKT A;  3UO0 A;  1E33 P;  1Y7A A;  3UN2 A;  2RH6 A;  1E2S P;  5LQQ A;  3WAW A;  1ANJ A;  1KH9 A;  1URB A;  1ZEB A;  4LR8 A;  1KHJ A;  5TJ3 A;  2D1G A;  1KH7 A;  3MK2 A;  1ELZ A;  4LR2 A;  1HQA A;  4UPK A;  1AJD A;  4ZG6 A;  3OT9 A;  3KD8 A;  2IUC B;  1SHQ A;  3A52 A;  4NWJ A;  2QZU A;  3M8Y A;  1AJA A;  4GTX A;  1KH5 A;  1N2L A;  3NKP A;  4YR1 A;  3NKQ A;  1ALK A;  2W8S A;  5AJ9 A;  4CXK A;  4LR7 A;  3SZY A;  3LXQ A;  4UPI A;  2GSN A;  4LR9 A;  3T01 A;  2W8D A;  3WAV A;  4MIV A;  4CYR A;  3BDH A;  3M8W A;  1KH4 A;  4GTZ A;  5IJS A;  3CMR A;  2W5Q A;  3NVL A;  4LRE A;  5EGE A;  1EJJ A;  1Y6V A;  3B5Q A;  3NKO A;  1ED8 A;  1ALJ A;  1O98 A;  1EW2 A;  2XRG A;  3NKM A;  3MK1 A;  3DYC A;  5DLW A;  3NKN A;  2GA3 A;  4KJD A;  4ZG7 A;  3BDG B;  4FDI A;  4LRD A;  1FSU A;  1K7H A;  5EGH A;  5L0B A;  5LRN A;  1ELX A;  1ED9 A;  1E3C P;  5L0K A;  2W5W A;  3TX0 A;  1O99 A;  2W5V A;  2GLQ A;  2W5S A;  1EI6 A;  2GSO A;  3Q3Q A;  2G9Y A;  4ZG9 A;  4KJG A;  4N7T A;  3DPC A;  1URA A;  5LRM A;  4FDJ A;  1EW8 A;  5K4P A;  5L0E A;  1B8J A;  4NWX A; 
#chains in the Genus database with same CATH topology
 3UNY A;  3MK0 A;  4QAX A;  1HDH A;  1KHK A;  5IJQ A;  3UN3 A;  2IFY A;  3UN5 A;  3WAY A;  1ELY A;  3IDD A;  4MHX A;  5GOV A;  5INH A;  1ANI A;  4KAV A;  4ZGA A;  1KHN A;  1HJK A;  4LQY A;  2W5R A;  2IUC A;  3NKR A;  1AJC A;  5KXA A;  1KHL A;  4LRF A;  3T00 A;  2W5T A;  5C66 A;  1ALI A;  4UOP A;  4GTW A;  1E1Z P;  1EQJ A;  2W5X A;  1AUK A;  5LIA A;  4UOR A;  3TG0 A;  2VQR A;  2X98 A;  4LRB A;  3ED4 A;  2GSU A;  4UPL A;  4CYS A;  5HRT A;  2XR9 A;  3IGZ B;  5DLT A;  1EW9 A;  4UPH A;  3WAX A;  3M7V A;  1ZED A;  4MY4 A;  1P49 A;  3SZZ A;  3BDG A;  4CXU A;  4CXS A;  1AJB A;  4B56 A;  3TWZ A;  3WBH A;  1N2K A;  3IGY B;  4KAY A;  4LRA A;  4TN0 A;  2ANH A;  4KM4 A;  3T02 A;  4UOO A;  5DLV A;  4LRC A;  3BDF A;  1ZEF A;  3M8Z A;  3E2D A;  1SHN A;  5GRR A;  1ALH A;  4GTY A;  2ZKT A;  3UO0 A;  1E33 P;  1Y7A A;  3UN2 A;  2RH6 A;  1E2S P;  5LQQ A;  3WAW A;  1ANJ A;  1KH9 A;  1URB A;  1ZEB A;  4LR8 A;  1KHJ A;  5TJ3 A;  2D1G A;  1KH7 A;  3MK2 A;  1ELZ A;  4LR2 A;  1HQA A;  4UPK A;  1AJD A;  4ZG6 A;  3OT9 A;  3KD8 A;  2IUC B;  1SHQ A;  3A52 A;  4NWJ A;  2QZU A;  3M8Y A;  1AJA A;  4GTX A;  1KH5 A;  1N2L A;  3NKP A;  4YR1 A;  3NKQ A;  1ALK A;  2W8S A;  5AJ9 A;  4CXK A;  4LR7 A;  3SZY A;  3LXQ A;  4UPI A;  2GSN A;  4LR9 A;  3T01 A;  2W8D A;  3WAV A;  4MIV A;  4CYR A;  3BDH A;  3M8W A;  1KH4 A;  4GTZ A;  5IJS A;  3CMR A;  2W5Q A;  3NVL A;  4LRE A;  5EGE A;  1EJJ A;  1Y6V A;  3B5Q A;  3NKO A;  1ED8 A;  1ALJ A;  1O98 A;  1EW2 A;  2XRG A;  3NKM A;  3MK1 A;  3DYC A;  5DLW A;  3NKN A;  2GA3 A;  4KJD A;  4ZG7 A;  3BDG B;  4FDI A;  4LRD A;  1FSU A;  1K7H A;  5EGH A;  5L0B A;  5LRN A;  1ELX A;  1ED9 A;  1E3C P;  5L0K A;  2W5W A;  3TX0 A;  1O99 A;  2W5V A;  2GLQ A;  2W5S A;  1EI6 A;  2GSO A;  3Q3Q A;  2G9Y A;  4ZG9 A;  4KJG A;  4N7T A;  3DPC A;  1URA A;  5LRM A;  4FDJ A;  1EW8 A;  5K4P A;  5L0E A;  1B8J A;  4NWX A; 
#chains in the Genus database with same CATH homology
 3UNY A;  3MK0 A;  4QAX A;  1HDH A;  1KHK A;  5IJQ A;  3UN3 A;  2IFY A;  3UN5 A;  3WAY A;  1ELY A;  3IDD A;  4MHX A;  5GOV A;  5INH A;  1ANI A;  4KAV A;  4ZGA A;  1KHN A;  1HJK A;  4LQY A;  2W5R A;  2IUC A;  3NKR A;  1AJC A;  5KXA A;  1KHL A;  4LRF A;  3T00 A;  2W5T A;  5C66 A;  1ALI A;  4UOP A;  4GTW A;  1E1Z P;  1EQJ A;  2W5X A;  1AUK A;  5LIA A;  4UOR A;  3TG0 A;  2VQR A;  2X98 A;  4LRB A;  3ED4 A;  2GSU A;  4UPL A;  4CYS A;  5HRT A;  2XR9 A;  3IGZ B;  5DLT A;  1EW9 A;  4UPH A;  3WAX A;  3M7V A;  1ZED A;  4MY4 A;  1P49 A;  3SZZ A;  3BDG A;  4CXU A;  4CXS A;  1AJB A;  4B56 A;  3TWZ A;  3WBH A;  1N2K A;  3IGY B;  4KAY A;  4LRA A;  4TN0 A;  2ANH A;  4KM4 A;  3T02 A;  4UOO A;  5DLV A;  4LRC A;  3BDF A;  1ZEF A;  3M8Z A;  3E2D A;  1SHN A;  5GRR A;  1ALH A;  4GTY A;  2ZKT A;  3UO0 A;  1E33 P;  1Y7A A;  3UN2 A;  2RH6 A;  1E2S P;  5LQQ A;  3WAW A;  1ANJ A;  1KH9 A;  1URB A;  1ZEB A;  4LR8 A;  1KHJ A;  5TJ3 A;  2D1G A;  1KH7 A;  3MK2 A;  1ELZ A;  4LR2 A;  1HQA A;  4UPK A;  1AJD A;  4ZG6 A;  3OT9 A;  3KD8 A;  2IUC B;  1SHQ A;  3A52 A;  4NWJ A;  2QZU A;  3M8Y A;  1AJA A;  4GTX A;  1KH5 A;  1N2L A;  3NKP A;  4YR1 A;  3NKQ A;  1ALK A;  2W8S A;  5AJ9 A;  4CXK A;  4LR7 A;  3SZY A;  3LXQ A;  4UPI A;  2GSN A;  4LR9 A;  3T01 A;  2W8D A;  3WAV A;  4MIV A;  4CYR A;  3BDH A;  3M8W A;  1KH4 A;  4GTZ A;  5IJS A;  3CMR A;  2W5Q A;  3NVL A;  4LRE A;  5EGE A;  1EJJ A;  1Y6V A;  3B5Q A;  3NKO A;  1ED8 A;  1ALJ A;  1O98 A;  1EW2 A;  2XRG A;  3NKM A;  3MK1 A;  3DYC A;  5DLW A;  3NKN A;  2GA3 A;  4KJD A;  4ZG7 A;  3BDG B;  4FDI A;  4LRD A;  1FSU A;  1K7H A;  5EGH A;  5L0B A;  5LRN A;  1ELX A;  1ED9 A;  1E3C P;  5L0K A;  2W5W A;  3TX0 A;  1O99 A;  2W5V A;  2GLQ A;  2W5S A;  1EI6 A;  2GSO A;  3Q3Q A;  2G9Y A;  4ZG9 A;  4KJG A;  4N7T A;  3DPC A;  1URA A;  5LRM A;  4FDJ A;  1EW8 A;  5K4P A;  5L0E A;  1B8J A;  4NWX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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