5LRMA

Structure of di-zinc mcr-1 in p41212 space group
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
Knots found
sequence length
323
structure length
312
Chain Sequence
TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords phosphatidylethanolamine transferase Mcr-1
publication title Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 126
structure length 312
sequence length 323
other databases KnotProt 2.0: S +31
ec nomenclature ec 2.7.-.-:
pdb deposition date 2016-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5lrmA00
2XR9A 3UN2A 4UPHA 5LRNA 3SZYA 4KAYA 3KD8A 3UN5A 1KH7A 3UNYA 1KHJA 2W5WA 3UN3A 3DPCA 1KH4A 2GSUA 3SZZA 1EI6A 1ALKA 1Y7AA 2GSNA 3T01A 3BDFA 4LR2A 3NKMA 5DLTA 2VQRA 1EW9A 1URBA 4UORA 2W5RA 3NKQA 1HQAA 4MHXA 4CXUA 5C66A 1SHQA 2IUCA 4TN0A 1KHNA 1AJDA 1N2LA 3NKNA 1E33P 4LRDA 4NWXA 4LRBA 3UO0A 2ANHA 3BDGA 3ED4A 4GTYA 5DLVA 4LR9A 1B8JA 4GTXA 1ELXA 3DYCA 5L0KA 3M8YA 3T00A 5LQQA 1P49A 2W5SA 5TJ3A 4LRAA 2GLQA 3M7VA 1ED8A 1ZEBA 2IUCB 1KHLA 3WAYA 5LIAA 5HRTA 4CXSA 5GOVA 4FDIA 4FDJA 4ZG9A 1EJJA 3BDGB 3WBHA 4LREA 3NVLA 1HDHA 4KJDA 5LRMA 1ZEFA 1KH5A 4UPIA 1ED9A 1Y6VA 2X98A 5KXAA 1K7HA 2XRGA 1HJKA 2G9YA 5IJQA 1ALJA 4LRFA 1AUKA 4ZG7A 2QZUA 3IGZB 1ALIA 1O98A 4QAXA 3BDHA 4LR7A 5GRRA 4KM4A 4MY4A 4UOPA 4MIVA 4GTWA 5AJ9A 1ALHA 4KAVA 1AJAA 3A52A 5DLWA 1ELYA 3NKPA 3IGYB 3WAWA 4LR8A 3TG0A 3Q3QA 3MK2A 3OT9A 5L0EA 4CXKA 1EW8A 1EQJA 2W5VA 1ELZA 1KH9A 2IFYA 3M8ZA 3MK1A 3WAXA 3WAVA 3LXQA 2W8SA 2W8DA 3TWZA 5EGEA 3TX0A 1ANIA 3NKRA 2RH6A 1SHNA 3NKOA 1ANJA 1E2SP 4KJGA 3CMRA 1AJCA 4NWJA 4ZGAA 2GA3A 1E1ZP 3E2DA 5INHA 1FSUA 4CYRA 2W5QA 2W5TA 3MK0A 4UPKA 4UOOA 3M8WA 3IDDA 4GTZA 3T02A 1AJBA 1URAA 4ZG6A 2D1GA 5EGHA 4B56A 5L0BA 1N2KA 1ZEDA 4UPLA 3B5QA 2ZKTA 1EW2A 5K4PA 4LRCA 4YR1A 5IJSA 1O99A 1KHKA 1E3CP 4LQYA 4N7TA 2W5XA 2GSOA 4CYSA
chains in the Genus database with same CATH superfamily
2XR9A 3UN2A 4UPHA 5LRNA 3SZYA 4KAYA 3KD8A 3UN5A 1KH7A 3UNYA 1KHJA 2W5WA 3UN3A 3DPCA 1KH4A 2GSUA 3SZZA 1EI6A 1ALKA 1Y7AA 2GSNA 3T01A 3BDFA 4LR2A 3NKMA 5DLTA 2VQRA 1EW9A 1URBA 4UORA 2W5RA 3NKQA 1HQAA 4MHXA 4CXUA 5C66A 1SHQA 2IUCA 4TN0A 1KHNA 1AJDA 1N2LA 3NKNA 1E33P 4LRDA 4NWXA 4LRBA 3UO0A 2ANHA 3BDGA 3ED4A 4GTYA 5DLVA 4LR9A 1B8JA 4GTXA 1ELXA 3DYCA 5L0KA 3M8YA 3T00A 5LQQA 1P49A 2W5SA 5TJ3A 4LRAA 2GLQA 3M7VA 1ED8A 1ZEBA 2IUCB 1KHLA 3WAYA 5LIAA 5HRTA 4CXSA 5GOVA 4FDIA 4FDJA 4ZG9A 1EJJA 3BDGB 3WBHA 4LREA 3NVLA 1HDHA 4KJDA 5LRMA 1ZEFA 1KH5A 4UPIA 1ED9A 1Y6VA 2X98A 5KXAA 1K7HA 2XRGA 1HJKA 2G9YA 5IJQA 1ALJA 4LRFA 1AUKA 4ZG7A 2QZUA 3IGZB 1ALIA 1O98A 4QAXA 3BDHA 4LR7A 5GRRA 4KM4A 4MY4A 4UOPA 4MIVA 4GTWA 5AJ9A 1ALHA 4KAVA 1AJAA 3A52A 5DLWA 1ELYA 3NKPA 3IGYB 3WAWA 4LR8A 3TG0A 3Q3QA 3MK2A 3OT9A 5L0EA 4CXKA 1EW8A 1EQJA 2W5VA 1ELZA 1KH9A 2IFYA 3M8ZA 3MK1A 3WAXA 3WAVA 3LXQA 2W8SA 2W8DA 3TWZA 5EGEA 3TX0A 1ANIA 3NKRA 2RH6A 1SHNA 3NKOA 1ANJA 1E2SP 4KJGA 3CMRA 1AJCA 4NWJA 4ZGAA 2GA3A 1E1ZP 3E2DA 5INHA 1FSUA 4CYRA 2W5QA 2W5TA 3MK0A 4UPKA 4UOOA 3M8WA 3IDDA 4GTZA 3T02A 1AJBA 1URAA 4ZG6A 2D1GA 5EGHA 4B56A 5L0BA 1N2KA 1ZEDA 4UPLA 3B5QA 2ZKTA 1EW2A 5K4PA 4LRCA 4YR1A 5IJSA 1O99A 1KHKA 1E3CP 4LQYA 4N7TA 2W5XA 2GSOA 4CYSA
chains in the Genus database with same CATH topology
2XR9A 3UN2A 4UPHA 5LRNA 3SZYA 4KAYA 3KD8A 3UN5A 1KH7A 3UNYA 1KHJA 2W5WA 3UN3A 3DPCA 1KH4A 2GSUA 3SZZA 1EI6A 1ALKA 1Y7AA 2GSNA 3T01A 3BDFA 4LR2A 3NKMA 5DLTA 2VQRA 1EW9A 1URBA 4UORA 2W5RA 3NKQA 1HQAA 4MHXA 4CXUA 5C66A 1SHQA 2IUCA 4TN0A 1KHNA 1AJDA 1N2LA 3NKNA 1E33P 4LRDA 4NWXA 4LRBA 3UO0A 2ANHA 3BDGA 3ED4A 4GTYA 5DLVA 4LR9A 1B8JA 4GTXA 1ELXA 3DYCA 5L0KA 3M8YA 3T00A 5LQQA 1P49A 2W5SA 5TJ3A 4LRAA 2GLQA 3M7VA 1ED8A 1ZEBA 2IUCB 1KHLA 3WAYA 5LIAA 5HRTA 4CXSA 5GOVA 4FDIA 4FDJA 4ZG9A 1EJJA 3BDGB 3WBHA 4LREA 3NVLA 1HDHA 4KJDA 5LRMA 1ZEFA 1KH5A 4UPIA 1ED9A 1Y6VA 2X98A 5KXAA 1K7HA 2XRGA 1HJKA 2G9YA 5IJQA 1ALJA 4LRFA 1AUKA 4ZG7A 2QZUA 3IGZB 1ALIA 1O98A 4QAXA 3BDHA 4LR7A 5GRRA 4KM4A 4MY4A 4UOPA 4MIVA 4GTWA 5AJ9A 1ALHA 4KAVA 1AJAA 3A52A 5DLWA 1ELYA 3NKPA 3IGYB 3WAWA 4LR8A 3TG0A 3Q3QA 3MK2A 3OT9A 5L0EA 4CXKA 1EW8A 1EQJA 2W5VA 1ELZA 1KH9A 2IFYA 3M8ZA 3MK1A 3WAXA 3WAVA 3LXQA 2W8SA 2W8DA 3TWZA 5EGEA 3TX0A 1ANIA 3NKRA 2RH6A 1SHNA 3NKOA 1ANJA 1E2SP 4KJGA 3CMRA 1AJCA 4NWJA 4ZGAA 2GA3A 1E1ZP 3E2DA 5INHA 1FSUA 4CYRA 2W5QA 2W5TA 3MK0A 4UPKA 4UOOA 3M8WA 3IDDA 4GTZA 3T02A 1AJBA 1URAA 4ZG6A 2D1GA 5EGHA 4B56A 5L0BA 1N2KA 1ZEDA 4UPLA 3B5QA 2ZKTA 1EW2A 5K4PA 4LRCA 4YR1A 5IJSA 1O99A 1KHKA 1E3CP 4LQYA 4N7TA 2W5XA 2GSOA 4CYSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XR9 A;  3UN2 A;  4UPH A;  5LRN A;  3SZY A;  4KAY A;  3KD8 A;  3UN5 A;  1KH7 A;  3UNY A;  1KHJ A;  2W5W A;  3UN3 A;  3DPC A;  1KH4 A;  2GSU A;  3SZZ A;  1EI6 A;  1ALK A;  1Y7A A;  2GSN A;  3T01 A;  3BDF A;  4LR2 A;  3NKM A;  5DLT A;  2VQR A;  1EW9 A;  1URB A;  4UOR A;  2W5R A;  3NKQ A;  1HQA A;  4MHX A;  4CXU A;  5C66 A;  1SHQ A;  2IUC A;  4TN0 A;  1KHN A;  1AJD A;  1N2L A;  3NKN A;  1E33 P;  4LRD A;  4NWX A;  4LRB A;  3UO0 A;  2ANH A;  3BDG A;  3ED4 A;  4GTY A;  5DLV A;  4LR9 A;  1B8J A;  4GTX A;  1ELX A;  3DYC A;  5L0K A;  3M8Y A;  3T00 A;  5LQQ A;  1P49 A;  2W5S A;  5TJ3 A;  4LRA A;  2GLQ A;  3M7V A;  1ED8 A;  1ZEB A;  2IUC B;  1KHL A;  3WAY A;  5LIA A;  5HRT A;  4CXS A;  5GOV A;  4FDI A;  4FDJ A;  4ZG9 A;  1EJJ A;  3BDG B;  3WBH A;  4LRE A;  3NVL A;  1HDH A;  4KJD A;  5LRM A;  1ZEF A;  1KH5 A;  4UPI A;  1ED9 A;  1Y6V A;  2X98 A;  5KXA A;  1K7H A;  2XRG A;  1HJK A;  2G9Y A;  5IJQ A;  1ALJ A;  4LRF A;  1AUK A;  4ZG7 A;  2QZU A;  3IGZ B;  1ALI A;  1O98 A;  4QAX A;  3BDH A;  4LR7 A;  5GRR A;  4KM4 A;  4MY4 A;  4UOP A;  4MIV A;  4GTW A;  5AJ9 A;  1ALH A;  4KAV A;  1AJA A;  3A52 A;  5DLW A;  1ELY A;  3NKP A;  3IGY B;  3WAW A;  4LR8 A;  3TG0 A;  3Q3Q A;  3MK2 A;  3OT9 A;  5L0E A;  4CXK A;  1EW8 A;  1EQJ A;  2W5V A;  1ELZ A;  1KH9 A;  2IFY A;  3M8Z A;  3MK1 A;  3WAX A;  3WAV A;  3LXQ A;  2W8S A;  2W8D A;  3TWZ A;  5EGE A;  3TX0 A;  1ANI A;  3NKR A;  2RH6 A;  1SHN A;  3NKO A;  1ANJ A;  1E2S P;  4KJG A;  3CMR A;  1AJC A;  4NWJ A;  4ZGA A;  2GA3 A;  1E1Z P;  3E2D A;  5INH A;  1FSU A;  4CYR A;  2W5Q A;  2W5T A;  3MK0 A;  4UPK A;  4UOO A;  3M8W A;  3IDD A;  4GTZ A;  3T02 A;  1AJB A;  1URA A;  4ZG6 A;  2D1G A;  5EGH A;  4B56 A;  5L0B A;  1N2K A;  1ZED A;  4UPL A;  3B5Q A;  2ZKT A;  1EW2 A;  5K4P A;  4LRC A;  4YR1 A;  5IJS A;  1O99 A;  1KHK A;  1E3C P;  4LQY A;  4N7T A;  2W5X A;  2GSO A;  4CYS A; 
#chains in the Genus database with same CATH topology
 2XR9 A;  3UN2 A;  4UPH A;  5LRN A;  3SZY A;  4KAY A;  3KD8 A;  3UN5 A;  1KH7 A;  3UNY A;  1KHJ A;  2W5W A;  3UN3 A;  3DPC A;  1KH4 A;  2GSU A;  3SZZ A;  1EI6 A;  1ALK A;  1Y7A A;  2GSN A;  3T01 A;  3BDF A;  4LR2 A;  3NKM A;  5DLT A;  2VQR A;  1EW9 A;  1URB A;  4UOR A;  2W5R A;  3NKQ A;  1HQA A;  4MHX A;  4CXU A;  5C66 A;  1SHQ A;  2IUC A;  4TN0 A;  1KHN A;  1AJD A;  1N2L A;  3NKN A;  1E33 P;  4LRD A;  4NWX A;  4LRB A;  3UO0 A;  2ANH A;  3BDG A;  3ED4 A;  4GTY A;  5DLV A;  4LR9 A;  1B8J A;  4GTX A;  1ELX A;  3DYC A;  5L0K A;  3M8Y A;  3T00 A;  5LQQ A;  1P49 A;  2W5S A;  5TJ3 A;  4LRA A;  2GLQ A;  3M7V A;  1ED8 A;  1ZEB A;  2IUC B;  1KHL A;  3WAY A;  5LIA A;  5HRT A;  4CXS A;  5GOV A;  4FDI A;  4FDJ A;  4ZG9 A;  1EJJ A;  3BDG B;  3WBH A;  4LRE A;  3NVL A;  1HDH A;  4KJD A;  5LRM A;  1ZEF A;  1KH5 A;  4UPI A;  1ED9 A;  1Y6V A;  2X98 A;  5KXA A;  1K7H A;  2XRG A;  1HJK A;  2G9Y A;  5IJQ A;  1ALJ A;  4LRF A;  1AUK A;  4ZG7 A;  2QZU A;  3IGZ B;  1ALI A;  1O98 A;  4QAX A;  3BDH A;  4LR7 A;  5GRR A;  4KM4 A;  4MY4 A;  4UOP A;  4MIV A;  4GTW A;  5AJ9 A;  1ALH A;  4KAV A;  1AJA A;  3A52 A;  5DLW A;  1ELY A;  3NKP A;  3IGY B;  3WAW A;  4LR8 A;  3TG0 A;  3Q3Q A;  3MK2 A;  3OT9 A;  5L0E A;  4CXK A;  1EW8 A;  1EQJ A;  2W5V A;  1ELZ A;  1KH9 A;  2IFY A;  3M8Z A;  3MK1 A;  3WAX A;  3WAV A;  3LXQ A;  2W8S A;  2W8D A;  3TWZ A;  5EGE A;  3TX0 A;  1ANI A;  3NKR A;  2RH6 A;  1SHN A;  3NKO A;  1ANJ A;  1E2S P;  4KJG A;  3CMR A;  1AJC A;  4NWJ A;  4ZGA A;  2GA3 A;  1E1Z P;  3E2D A;  5INH A;  1FSU A;  4CYR A;  2W5Q A;  2W5T A;  3MK0 A;  4UPK A;  4UOO A;  3M8W A;  3IDD A;  4GTZ A;  3T02 A;  1AJB A;  1URA A;  4ZG6 A;  2D1G A;  5EGH A;  4B56 A;  5L0B A;  1N2K A;  1ZED A;  4UPL A;  3B5Q A;  2ZKT A;  1EW2 A;  5K4P A;  4LRC A;  4YR1 A;  5IJS A;  1O99 A;  1KHK A;  1E3C P;  4LQY A;  4N7T A;  2W5X A;  2GSO A;  4CYS A; 
#chains in the Genus database with same CATH homology
 2XR9 A;  3UN2 A;  4UPH A;  5LRN A;  3SZY A;  4KAY A;  3KD8 A;  3UN5 A;  1KH7 A;  3UNY A;  1KHJ A;  2W5W A;  3UN3 A;  3DPC A;  1KH4 A;  2GSU A;  3SZZ A;  1EI6 A;  1ALK A;  1Y7A A;  2GSN A;  3T01 A;  3BDF A;  4LR2 A;  3NKM A;  5DLT A;  2VQR A;  1EW9 A;  1URB A;  4UOR A;  2W5R A;  3NKQ A;  1HQA A;  4MHX A;  4CXU A;  5C66 A;  1SHQ A;  2IUC A;  4TN0 A;  1KHN A;  1AJD A;  1N2L A;  3NKN A;  1E33 P;  4LRD A;  4NWX A;  4LRB A;  3UO0 A;  2ANH A;  3BDG A;  3ED4 A;  4GTY A;  5DLV A;  4LR9 A;  1B8J A;  4GTX A;  1ELX A;  3DYC A;  5L0K A;  3M8Y A;  3T00 A;  5LQQ A;  1P49 A;  2W5S A;  5TJ3 A;  4LRA A;  2GLQ A;  3M7V A;  1ED8 A;  1ZEB A;  2IUC B;  1KHL A;  3WAY A;  5LIA A;  5HRT A;  4CXS A;  5GOV A;  4FDI A;  4FDJ A;  4ZG9 A;  1EJJ A;  3BDG B;  3WBH A;  4LRE A;  3NVL A;  1HDH A;  4KJD A;  5LRM A;  1ZEF A;  1KH5 A;  4UPI A;  1ED9 A;  1Y6V A;  2X98 A;  5KXA A;  1K7H A;  2XRG A;  1HJK A;  2G9Y A;  5IJQ A;  1ALJ A;  4LRF A;  1AUK A;  4ZG7 A;  2QZU A;  3IGZ B;  1ALI A;  1O98 A;  4QAX A;  3BDH A;  4LR7 A;  5GRR A;  4KM4 A;  4MY4 A;  4UOP A;  4MIV A;  4GTW A;  5AJ9 A;  1ALH A;  4KAV A;  1AJA A;  3A52 A;  5DLW A;  1ELY A;  3NKP A;  3IGY B;  3WAW A;  4LR8 A;  3TG0 A;  3Q3Q A;  3MK2 A;  3OT9 A;  5L0E A;  4CXK A;  1EW8 A;  1EQJ A;  2W5V A;  1ELZ A;  1KH9 A;  2IFY A;  3M8Z A;  3MK1 A;  3WAX A;  3WAV A;  3LXQ A;  2W8S A;  2W8D A;  3TWZ A;  5EGE A;  3TX0 A;  1ANI A;  3NKR A;  2RH6 A;  1SHN A;  3NKO A;  1ANJ A;  1E2S P;  4KJG A;  3CMR A;  1AJC A;  4NWJ A;  4ZGA A;  2GA3 A;  1E1Z P;  3E2D A;  5INH A;  1FSU A;  4CYR A;  2W5Q A;  2W5T A;  3MK0 A;  4UPK A;  4UOO A;  3M8W A;  3IDD A;  4GTZ A;  3T02 A;  1AJB A;  1URA A;  4ZG6 A;  2D1G A;  5EGH A;  4B56 A;  5L0B A;  1N2K A;  1ZED A;  4UPL A;  3B5Q A;  2ZKT A;  1EW2 A;  5K4P A;  4LRC A;  4YR1 A;  5IJS A;  1O99 A;  1KHK A;  1E3C P;  4LQY A;  4N7T A;  2W5X A;  2GSO A;  4CYS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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