5LRMA

Structure of di-zinc mcr-1 in p41212 space group
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
Knots found
sequence length
323
structure length
312
Chain Sequence
TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords phosphatidylethanolamine transferase Mcr-1
publication title Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.
pubmed doi rcsb
source organism Escherichia coli
total genus 126
structure length 312
sequence length 323
other databases KnotProt 2.0: S +31
ec nomenclature ec 2.7.-.-:
pdb deposition date 2016-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5lrmA00
4LQYA 3WAVA 3UO0A 2W8SA 3TX0A 5LQQA 4KJDA 4MY4A 3NKPA 4NWJA 1EW9A 4UORA 2ANHA 5EGEA 1E3CP 1ZEFA 1K7HA 3NKQA 1KH4A 3B5QA 4LRFA 4CXKA 2XRGA 1AJBA 3TWZA 5EGHA 4GTYA 4CYRA 4LR2A 4TN0A 2W5TA 3OT9A 5LRNA 2IUCB 4YR1A 5INHA 2GA3A 4KJGA 1AJDA 2ZKTA 1ELXA 5TJ3A 2GSUA 1ANIA 4GTXA 1KHLA 4KAVA 1EJJA 3Q3QA 1Y7AA 3T02A 4ZG6A 5DLVA 5C66A 1ELYA 1SHNA 2X98A 3M7VA 3NKRA 4LRCA 2W5QA 3T01A 1ALKA 5L0EA 3NKOA 3E2DA 3UNYA 1AJCA 3LXQA 1ALIA 4LR9A 4ZG7A 1AJAA 1EW8A 1AUKA 1Y6VA 1HJKA 2W5WA 3KD8A 4B56A 1URAA 4UOOA 1EQJA 3M8WA 1KHKA 3BDGA 3BDFA 1HQAA 1URBA 1KH9A 3IGZB 3IDDA 1E33P 1P49A 5GRRA 5HRTA 1O98A 3M8ZA 4MIVA 4LR7A 4UPKA 2VQRA 2GSNA 4UPHA 2GLQA 4QAXA 3ED4A 3WAYA 3DPCA 5LRMA 1ELZA 1ALHA 5DLTA 3DYCA 3IGYB 4UPIA 3TG0A 4UOPA 1SHQA 5AJ9A 3UN3A 3UN5A 2W5RA 3BDGB 2D1GA 1FSUA 2RH6A 3WBHA 2QZUA 3A52A 3NVLA 4LRDA 5LIAA 3MK1A 4CXSA 1B8JA 4NWXA 5L0BA 3BDHA 3MK0A 4KAYA 4LRBA 5K4PA 5L0KA 4GTZA 2W8DA 4GTWA 5KXAA 2XR9A 2IFYA 1EI6A 4ZG9A 1N2KA 4N7TA 3SZYA 3UN2A 1ED8A 1ED9A 1N2LA 1KH5A 2W5XA 3T00A 1ZEBA 5IJSA 4UPLA 4KM4A 2GSOA 4LRAA 5IJQA 3SZZA 4FDIA 3M8YA 4CYSA 1E1ZP 4ZGAA 3WAXA 1KH7A 1O99A 5GOVA 5DLWA 3NKNA 3CMRA 1E2SP 3NKMA 4LREA 4MHXA 1ZEDA 3MK2A 2W5SA 2W5VA 1ANJA 1KHNA 1KHJA 2G9YA 4LR8A 4CXUA 3WAWA 4FDJA 1EW2A 1ALJA 1HDHA 2IUCA
chains in the Genus database with same CATH superfamily
4LQYA 3WAVA 3UO0A 2W8SA 3TX0A 5LQQA 4KJDA 4MY4A 3NKPA 4NWJA 1EW9A 4UORA 2ANHA 5EGEA 1E3CP 1ZEFA 1K7HA 3NKQA 1KH4A 3B5QA 4LRFA 4CXKA 2XRGA 1AJBA 3TWZA 5EGHA 4GTYA 4CYRA 4LR2A 4TN0A 2W5TA 3OT9A 5LRNA 2IUCB 4YR1A 5INHA 2GA3A 4KJGA 1AJDA 2ZKTA 1ELXA 5TJ3A 2GSUA 1ANIA 4GTXA 1KHLA 4KAVA 1EJJA 3Q3QA 1Y7AA 3T02A 4ZG6A 5DLVA 5C66A 1ELYA 1SHNA 2X98A 3M7VA 3NKRA 4LRCA 2W5QA 3T01A 1ALKA 5L0EA 3NKOA 3E2DA 3UNYA 1AJCA 3LXQA 1ALIA 4LR9A 4ZG7A 1AJAA 1EW8A 1AUKA 1Y6VA 1HJKA 2W5WA 3KD8A 4B56A 1URAA 4UOOA 1EQJA 3M8WA 1KHKA 3BDGA 3BDFA 1HQAA 1URBA 1KH9A 3IGZB 3IDDA 1E33P 1P49A 5GRRA 5HRTA 1O98A 3M8ZA 4MIVA 4LR7A 4UPKA 2VQRA 2GSNA 4UPHA 2GLQA 4QAXA 3ED4A 3WAYA 3DPCA 5LRMA 1ELZA 1ALHA 5DLTA 3DYCA 3IGYB 4UPIA 3TG0A 4UOPA 1SHQA 5AJ9A 3UN3A 3UN5A 2W5RA 3BDGB 2D1GA 1FSUA 2RH6A 3WBHA 2QZUA 3A52A 3NVLA 4LRDA 5LIAA 3MK1A 4CXSA 1B8JA 4NWXA 5L0BA 3BDHA 3MK0A 4KAYA 4LRBA 5K4PA 5L0KA 4GTZA 2W8DA 4GTWA 5KXAA 2XR9A 2IFYA 1EI6A 4ZG9A 1N2KA 4N7TA 3SZYA 3UN2A 1ED8A 1ED9A 1N2LA 1KH5A 2W5XA 3T00A 1ZEBA 5IJSA 4UPLA 4KM4A 2GSOA 4LRAA 5IJQA 3SZZA 4FDIA 3M8YA 4CYSA 1E1ZP 4ZGAA 3WAXA 1KH7A 1O99A 5GOVA 5DLWA 3NKNA 3CMRA 1E2SP 3NKMA 4LREA 4MHXA 1ZEDA 3MK2A 2W5SA 2W5VA 1ANJA 1KHNA 1KHJA 2G9YA 4LR8A 4CXUA 3WAWA 4FDJA 1EW2A 1ALJA 1HDHA 2IUCA
chains in the Genus database with same CATH topology
4LQYA 3WAVA 3UO0A 2W8SA 3TX0A 5LQQA 4KJDA 4MY4A 3NKPA 4NWJA 1EW9A 4UORA 2ANHA 5EGEA 1E3CP 1ZEFA 1K7HA 3NKQA 1KH4A 3B5QA 4LRFA 4CXKA 2XRGA 1AJBA 3TWZA 5EGHA 4GTYA 4CYRA 4LR2A 4TN0A 2W5TA 3OT9A 5LRNA 2IUCB 4YR1A 5INHA 2GA3A 4KJGA 1AJDA 2ZKTA 1ELXA 5TJ3A 2GSUA 1ANIA 4GTXA 1KHLA 4KAVA 1EJJA 3Q3QA 1Y7AA 3T02A 4ZG6A 5DLVA 5C66A 1ELYA 1SHNA 2X98A 3M7VA 3NKRA 4LRCA 2W5QA 3T01A 1ALKA 5L0EA 3NKOA 3E2DA 3UNYA 1AJCA 3LXQA 1ALIA 4LR9A 4ZG7A 1AJAA 1EW8A 1AUKA 1Y6VA 1HJKA 2W5WA 3KD8A 4B56A 1URAA 4UOOA 1EQJA 3M8WA 1KHKA 3BDGA 3BDFA 1HQAA 1URBA 1KH9A 3IGZB 3IDDA 1E33P 1P49A 5GRRA 5HRTA 1O98A 3M8ZA 4MIVA 4LR7A 4UPKA 2VQRA 2GSNA 4UPHA 2GLQA 4QAXA 3ED4A 3WAYA 3DPCA 5LRMA 1ELZA 1ALHA 5DLTA 3DYCA 3IGYB 4UPIA 3TG0A 4UOPA 1SHQA 5AJ9A 3UN3A 3UN5A 2W5RA 3BDGB 2D1GA 1FSUA 2RH6A 3WBHA 2QZUA 3A52A 3NVLA 4LRDA 5LIAA 3MK1A 4CXSA 1B8JA 4NWXA 5L0BA 3BDHA 3MK0A 4KAYA 4LRBA 5K4PA 5L0KA 4GTZA 2W8DA 4GTWA 5KXAA 2XR9A 2IFYA 1EI6A 4ZG9A 1N2KA 4N7TA 3SZYA 3UN2A 1ED8A 1ED9A 1N2LA 1KH5A 2W5XA 3T00A 1ZEBA 5IJSA 4UPLA 4KM4A 2GSOA 4LRAA 5IJQA 3SZZA 4FDIA 3M8YA 4CYSA 1E1ZP 4ZGAA 3WAXA 1KH7A 1O99A 5GOVA 5DLWA 3NKNA 3CMRA 1E2SP 3NKMA 4LREA 4MHXA 1ZEDA 3MK2A 2W5SA 2W5VA 1ANJA 1KHNA 1KHJA 2G9YA 4LR8A 4CXUA 3WAWA 4FDJA 1EW2A 1ALJA 1HDHA 2IUCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LQY A;  3WAV A;  3UO0 A;  2W8S A;  3TX0 A;  5LQQ A;  4KJD A;  4MY4 A;  3NKP A;  4NWJ A;  1EW9 A;  4UOR A;  2ANH A;  5EGE A;  1E3C P;  1ZEF A;  1K7H A;  3NKQ A;  1KH4 A;  3B5Q A;  4LRF A;  4CXK A;  2XRG A;  1AJB A;  3TWZ A;  5EGH A;  4GTY A;  4CYR A;  4LR2 A;  4TN0 A;  2W5T A;  3OT9 A;  5LRN A;  2IUC B;  4YR1 A;  5INH A;  2GA3 A;  4KJG A;  1AJD A;  2ZKT A;  1ELX A;  5TJ3 A;  2GSU A;  1ANI A;  4GTX A;  1KHL A;  4KAV A;  1EJJ A;  3Q3Q A;  1Y7A A;  3T02 A;  4ZG6 A;  5DLV A;  5C66 A;  1ELY A;  1SHN A;  2X98 A;  3M7V A;  3NKR A;  4LRC A;  2W5Q A;  3T01 A;  1ALK A;  5L0E A;  3NKO A;  3E2D A;  3UNY A;  1AJC A;  3LXQ A;  1ALI A;  4LR9 A;  4ZG7 A;  1AJA A;  1EW8 A;  1AUK A;  1Y6V A;  1HJK A;  2W5W A;  3KD8 A;  4B56 A;  1URA A;  4UOO A;  1EQJ A;  3M8W A;  1KHK A;  3BDG A;  3BDF A;  1HQA A;  1URB A;  1KH9 A;  3IGZ B;  3IDD A;  1E33 P;  1P49 A;  5GRR A;  5HRT A;  1O98 A;  3M8Z A;  4MIV A;  4LR7 A;  4UPK A;  2VQR A;  2GSN A;  4UPH A;  2GLQ A;  4QAX A;  3ED4 A;  3WAY A;  3DPC A;  5LRM A;  1ELZ A;  1ALH A;  5DLT A;  3DYC A;  3IGY B;  4UPI A;  3TG0 A;  4UOP A;  1SHQ A;  5AJ9 A;  3UN3 A;  3UN5 A;  2W5R A;  3BDG B;  2D1G A;  1FSU A;  2RH6 A;  3WBH A;  2QZU A;  3A52 A;  3NVL A;  4LRD A;  5LIA A;  3MK1 A;  4CXS A;  1B8J A;  4NWX A;  5L0B A;  3BDH A;  3MK0 A;  4KAY A;  4LRB A;  5K4P A;  5L0K A;  4GTZ A;  2W8D A;  4GTW A;  5KXA A;  2XR9 A;  2IFY A;  1EI6 A;  4ZG9 A;  1N2K A;  4N7T A;  3SZY A;  3UN2 A;  1ED8 A;  1ED9 A;  1N2L A;  1KH5 A;  2W5X A;  3T00 A;  1ZEB A;  5IJS A;  4UPL A;  4KM4 A;  2GSO A;  4LRA A;  5IJQ A;  3SZZ A;  4FDI A;  3M8Y A;  4CYS A;  1E1Z P;  4ZGA A;  3WAX A;  1KH7 A;  1O99 A;  5GOV A;  5DLW A;  3NKN A;  3CMR A;  1E2S P;  3NKM A;  4LRE A;  4MHX A;  1ZED A;  3MK2 A;  2W5S A;  2W5V A;  1ANJ A;  1KHN A;  1KHJ A;  2G9Y A;  4LR8 A;  4CXU A;  3WAW A;  4FDJ A;  1EW2 A;  1ALJ A;  1HDH A;  2IUC A; 
#chains in the Genus database with same CATH topology
 4LQY A;  3WAV A;  3UO0 A;  2W8S A;  3TX0 A;  5LQQ A;  4KJD A;  4MY4 A;  3NKP A;  4NWJ A;  1EW9 A;  4UOR A;  2ANH A;  5EGE A;  1E3C P;  1ZEF A;  1K7H A;  3NKQ A;  1KH4 A;  3B5Q A;  4LRF A;  4CXK A;  2XRG A;  1AJB A;  3TWZ A;  5EGH A;  4GTY A;  4CYR A;  4LR2 A;  4TN0 A;  2W5T A;  3OT9 A;  5LRN A;  2IUC B;  4YR1 A;  5INH A;  2GA3 A;  4KJG A;  1AJD A;  2ZKT A;  1ELX A;  5TJ3 A;  2GSU A;  1ANI A;  4GTX A;  1KHL A;  4KAV A;  1EJJ A;  3Q3Q A;  1Y7A A;  3T02 A;  4ZG6 A;  5DLV A;  5C66 A;  1ELY A;  1SHN A;  2X98 A;  3M7V A;  3NKR A;  4LRC A;  2W5Q A;  3T01 A;  1ALK A;  5L0E A;  3NKO A;  3E2D A;  3UNY A;  1AJC A;  3LXQ A;  1ALI A;  4LR9 A;  4ZG7 A;  1AJA A;  1EW8 A;  1AUK A;  1Y6V A;  1HJK A;  2W5W A;  3KD8 A;  4B56 A;  1URA A;  4UOO A;  1EQJ A;  3M8W A;  1KHK A;  3BDG A;  3BDF A;  1HQA A;  1URB A;  1KH9 A;  3IGZ B;  3IDD A;  1E33 P;  1P49 A;  5GRR A;  5HRT A;  1O98 A;  3M8Z A;  4MIV A;  4LR7 A;  4UPK A;  2VQR A;  2GSN A;  4UPH A;  2GLQ A;  4QAX A;  3ED4 A;  3WAY A;  3DPC A;  5LRM A;  1ELZ A;  1ALH A;  5DLT A;  3DYC A;  3IGY B;  4UPI A;  3TG0 A;  4UOP A;  1SHQ A;  5AJ9 A;  3UN3 A;  3UN5 A;  2W5R A;  3BDG B;  2D1G A;  1FSU A;  2RH6 A;  3WBH A;  2QZU A;  3A52 A;  3NVL A;  4LRD A;  5LIA A;  3MK1 A;  4CXS A;  1B8J A;  4NWX A;  5L0B A;  3BDH A;  3MK0 A;  4KAY A;  4LRB A;  5K4P A;  5L0K A;  4GTZ A;  2W8D A;  4GTW A;  5KXA A;  2XR9 A;  2IFY A;  1EI6 A;  4ZG9 A;  1N2K A;  4N7T A;  3SZY A;  3UN2 A;  1ED8 A;  1ED9 A;  1N2L A;  1KH5 A;  2W5X A;  3T00 A;  1ZEB A;  5IJS A;  4UPL A;  4KM4 A;  2GSO A;  4LRA A;  5IJQ A;  3SZZ A;  4FDI A;  3M8Y A;  4CYS A;  1E1Z P;  4ZGA A;  3WAX A;  1KH7 A;  1O99 A;  5GOV A;  5DLW A;  3NKN A;  3CMR A;  1E2S P;  3NKM A;  4LRE A;  4MHX A;  1ZED A;  3MK2 A;  2W5S A;  2W5V A;  1ANJ A;  1KHN A;  1KHJ A;  2G9Y A;  4LR8 A;  4CXU A;  3WAW A;  4FDJ A;  1EW2 A;  1ALJ A;  1HDH A;  2IUC A; 
#chains in the Genus database with same CATH homology
 4LQY A;  3WAV A;  3UO0 A;  2W8S A;  3TX0 A;  5LQQ A;  4KJD A;  4MY4 A;  3NKP A;  4NWJ A;  1EW9 A;  4UOR A;  2ANH A;  5EGE A;  1E3C P;  1ZEF A;  1K7H A;  3NKQ A;  1KH4 A;  3B5Q A;  4LRF A;  4CXK A;  2XRG A;  1AJB A;  3TWZ A;  5EGH A;  4GTY A;  4CYR A;  4LR2 A;  4TN0 A;  2W5T A;  3OT9 A;  5LRN A;  2IUC B;  4YR1 A;  5INH A;  2GA3 A;  4KJG A;  1AJD A;  2ZKT A;  1ELX A;  5TJ3 A;  2GSU A;  1ANI A;  4GTX A;  1KHL A;  4KAV A;  1EJJ A;  3Q3Q A;  1Y7A A;  3T02 A;  4ZG6 A;  5DLV A;  5C66 A;  1ELY A;  1SHN A;  2X98 A;  3M7V A;  3NKR A;  4LRC A;  2W5Q A;  3T01 A;  1ALK A;  5L0E A;  3NKO A;  3E2D A;  3UNY A;  1AJC A;  3LXQ A;  1ALI A;  4LR9 A;  4ZG7 A;  1AJA A;  1EW8 A;  1AUK A;  1Y6V A;  1HJK A;  2W5W A;  3KD8 A;  4B56 A;  1URA A;  4UOO A;  1EQJ A;  3M8W A;  1KHK A;  3BDG A;  3BDF A;  1HQA A;  1URB A;  1KH9 A;  3IGZ B;  3IDD A;  1E33 P;  1P49 A;  5GRR A;  5HRT A;  1O98 A;  3M8Z A;  4MIV A;  4LR7 A;  4UPK A;  2VQR A;  2GSN A;  4UPH A;  2GLQ A;  4QAX A;  3ED4 A;  3WAY A;  3DPC A;  5LRM A;  1ELZ A;  1ALH A;  5DLT A;  3DYC A;  3IGY B;  4UPI A;  3TG0 A;  4UOP A;  1SHQ A;  5AJ9 A;  3UN3 A;  3UN5 A;  2W5R A;  3BDG B;  2D1G A;  1FSU A;  2RH6 A;  3WBH A;  2QZU A;  3A52 A;  3NVL A;  4LRD A;  5LIA A;  3MK1 A;  4CXS A;  1B8J A;  4NWX A;  5L0B A;  3BDH A;  3MK0 A;  4KAY A;  4LRB A;  5K4P A;  5L0K A;  4GTZ A;  2W8D A;  4GTW A;  5KXA A;  2XR9 A;  2IFY A;  1EI6 A;  4ZG9 A;  1N2K A;  4N7T A;  3SZY A;  3UN2 A;  1ED8 A;  1ED9 A;  1N2L A;  1KH5 A;  2W5X A;  3T00 A;  1ZEB A;  5IJS A;  4UPL A;  4KM4 A;  2GSO A;  4LRA A;  5IJQ A;  3SZZ A;  4FDI A;  3M8Y A;  4CYS A;  1E1Z P;  4ZGA A;  3WAX A;  1KH7 A;  1O99 A;  5GOV A;  5DLW A;  3NKN A;  3CMR A;  1E2S P;  3NKM A;  4LRE A;  4MHX A;  1ZED A;  3MK2 A;  2W5S A;  2W5V A;  1ANJ A;  1KHN A;  1KHJ A;  2G9Y A;  4LR8 A;  4CXU A;  3WAW A;  4FDJ A;  1EW2 A;  1ALJ A;  1HDH A;  2IUC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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