1SHNA

Crystal structure of shrimp alkaline phosphatase with phosphate bound
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
b'EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords alkaline phosphatase
publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shnA00
1ANJA 1Y6VA 2W5QA 1ED9A 1KH9A 4LR7A 3A52A 4CYRA 2X98A 4LR8A 3BDHA 3MK1A 4UPLA 4CXKA 5KXAA 3BDFA 5IJQA 4ZG9A 3WAVA 5IJSA 2W5XA 2W5WA 4GTXA 3DPCA 2XR9A 1KH7A 5L0KA 5TJ3A 4ZG6A 1SHNA 2W5VA 2D1GA 4UPIA 5AJ9A 4KJGA 2RH6A 3ED4A 1URBA 3KD8A 3T02A 4LRCA 2G9YA 1N2LA 1AJCA 3NKPA 1AJDA 3SZZA 4KAYA 4CXUA 3UNYA 4ZG7A 5EGHA 5K4PA 1EW9A 4LRFA 2W8DA 3BDGB 1HQAA 3BDGA 3TWZA 1ED8A 3E2DA 3NKOA 5LRMA 3NKMA 5INHA 1ZEDA 5HRTA 1EJJA 1O99A 3UO0A 3MK2A 1KHKA 1ANIA 4TN0A 5GRRA 4ZGAA 1B8JA 4GTWA 4FDIA 1HDHA 5LIAA 3B5QA 4LQYA 4UPHA 4KM4A 3T01A 5L0BA 4UOOA 5L0EA 4GTYA 2GA3A 2GSOA 1EQJA 1KH4A 3DYCA 4N7TA 1ALIA 2QZUA 1ELYA 2W5RA 2ZKTA 4YR1A 1ZEBA 2ANHA 4KJDA 3SZYA 2IUCB 1E3CP 4LRAA 2IUCA 2GSNA 1E1ZP 1P49A 4UOPA 5DLTA 3UN3A 3NKQA 4GTZA 3UN2A 3WAYA 1E2SP 3TG0A 5DLWA 5DLVA 1ALKA 4MY4A 1EI6A 2W8SA 4B56A 1AUKA 1O98A 3M8ZA 1SHQA 1E33P 1KH5A 4KAVA 3WAWA 4MHXA 1ZEFA 5LQQA 1N2KA 1KHJA 3NKRA 4NWJA 1ALJA 2W5TA 3WAXA 1K7HA 1EW2A 4FDJA 1KHNA 1AJBA 4MIVA 1FSUA 5GOVA 1AJAA 2GLQA 3M7VA 2W5SA 3M8WA 4LREA 4UORA 4LRDA 5C66A 5LRNA 3NKNA 1EW8A 4CXSA 3T00A 2VQRA 1HJKA 3IDDA 4QAXA 2GSUA 4NWXA 1ELZA 4LR9A 3M8YA 1ALHA 1ELXA 1KHLA 4UPKA 2IFYA 3OT9A 3CMRA 3NVLA 3UN5A 1Y7AA 4LR2A 3TX0A 3IGZB 4LRBA 4CYSA 5EGEA 2XRGA 3LXQA 3IGYB 3Q3QA 3WBHA 1URAA 3MK0A
chains in the Genus database with same CATH superfamily
1ANJA 1Y6VA 2W5QA 1ED9A 1KH9A 4LR7A 3A52A 4CYRA 2X98A 4LR8A 3BDHA 3MK1A 4UPLA 4CXKA 5KXAA 3BDFA 5IJQA 4ZG9A 3WAVA 5IJSA 2W5XA 2W5WA 4GTXA 3DPCA 2XR9A 1KH7A 5L0KA 5TJ3A 4ZG6A 1SHNA 2W5VA 2D1GA 4UPIA 5AJ9A 4KJGA 2RH6A 3ED4A 1URBA 3KD8A 3T02A 4LRCA 2G9YA 1N2LA 1AJCA 3NKPA 1AJDA 3SZZA 4KAYA 4CXUA 3UNYA 4ZG7A 5EGHA 5K4PA 1EW9A 4LRFA 2W8DA 3BDGB 1HQAA 3BDGA 3TWZA 1ED8A 3E2DA 3NKOA 5LRMA 3NKMA 5INHA 1ZEDA 5HRTA 1EJJA 1O99A 3UO0A 3MK2A 1KHKA 1ANIA 4TN0A 5GRRA 4ZGAA 1B8JA 4GTWA 4FDIA 1HDHA 5LIAA 3B5QA 4LQYA 4UPHA 4KM4A 3T01A 5L0BA 4UOOA 5L0EA 4GTYA 2GA3A 2GSOA 1EQJA 1KH4A 3DYCA 4N7TA 1ALIA 2QZUA 1ELYA 2W5RA 2ZKTA 4YR1A 1ZEBA 2ANHA 4KJDA 3SZYA 2IUCB 1E3CP 4LRAA 2IUCA 2GSNA 1E1ZP 1P49A 4UOPA 5DLTA 3UN3A 3NKQA 4GTZA 3UN2A 3WAYA 1E2SP 3TG0A 5DLWA 5DLVA 1ALKA 4MY4A 1EI6A 2W8SA 4B56A 1AUKA 1O98A 3M8ZA 1SHQA 1E33P 1KH5A 4KAVA 3WAWA 4MHXA 1ZEFA 5LQQA 1N2KA 1KHJA 3NKRA 4NWJA 1ALJA 2W5TA 3WAXA 1K7HA 1EW2A 4FDJA 1KHNA 1AJBA 4MIVA 1FSUA 5GOVA 1AJAA 2GLQA 3M7VA 2W5SA 3M8WA 4LREA 4UORA 4LRDA 5C66A 5LRNA 3NKNA 1EW8A 4CXSA 3T00A 2VQRA 1HJKA 3IDDA 4QAXA 2GSUA 4NWXA 1ELZA 4LR9A 3M8YA 1ALHA 1ELXA 1KHLA 4UPKA 2IFYA 3OT9A 3CMRA 3NVLA 3UN5A 1Y7AA 4LR2A 3TX0A 3IGZB 4LRBA 4CYSA 5EGEA 2XRGA 3LXQA 3IGYB 3Q3QA 3WBHA 1URAA 3MK0A
chains in the Genus database with same CATH topology
1ANJA 1Y6VA 2W5QA 1ED9A 1KH9A 4LR7A 3A52A 4CYRA 2X98A 4LR8A 3BDHA 3MK1A 4UPLA 4CXKA 5KXAA 3BDFA 5IJQA 4ZG9A 3WAVA 5IJSA 2W5XA 2W5WA 4GTXA 3DPCA 2XR9A 1KH7A 5L0KA 5TJ3A 4ZG6A 1SHNA 2W5VA 2D1GA 4UPIA 5AJ9A 4KJGA 2RH6A 3ED4A 1URBA 3KD8A 3T02A 4LRCA 2G9YA 1N2LA 1AJCA 3NKPA 1AJDA 3SZZA 4KAYA 4CXUA 3UNYA 4ZG7A 5EGHA 5K4PA 1EW9A 4LRFA 2W8DA 3BDGB 1HQAA 3BDGA 3TWZA 1ED8A 3E2DA 3NKOA 5LRMA 3NKMA 5INHA 1ZEDA 5HRTA 1EJJA 1O99A 3UO0A 3MK2A 1KHKA 1ANIA 4TN0A 5GRRA 4ZGAA 1B8JA 4GTWA 4FDIA 1HDHA 5LIAA 3B5QA 4LQYA 4UPHA 4KM4A 3T01A 5L0BA 4UOOA 5L0EA 4GTYA 2GA3A 2GSOA 1EQJA 1KH4A 3DYCA 4N7TA 1ALIA 2QZUA 1ELYA 2W5RA 2ZKTA 4YR1A 1ZEBA 2ANHA 4KJDA 3SZYA 2IUCB 1E3CP 4LRAA 2IUCA 2GSNA 1E1ZP 1P49A 4UOPA 5DLTA 3UN3A 3NKQA 4GTZA 3UN2A 3WAYA 1E2SP 3TG0A 5DLWA 5DLVA 1ALKA 4MY4A 1EI6A 2W8SA 4B56A 1AUKA 1O98A 3M8ZA 1SHQA 1E33P 1KH5A 4KAVA 3WAWA 4MHXA 1ZEFA 5LQQA 1N2KA 1KHJA 3NKRA 4NWJA 1ALJA 2W5TA 3WAXA 1K7HA 1EW2A 4FDJA 1KHNA 1AJBA 4MIVA 1FSUA 5GOVA 1AJAA 2GLQA 3M7VA 2W5SA 3M8WA 4LREA 4UORA 4LRDA 5C66A 5LRNA 3NKNA 1EW8A 4CXSA 3T00A 2VQRA 1HJKA 3IDDA 4QAXA 2GSUA 4NWXA 1ELZA 4LR9A 3M8YA 1ALHA 1ELXA 1KHLA 4UPKA 2IFYA 3OT9A 3CMRA 3NVLA 3UN5A 1Y7AA 4LR2A 3TX0A 3IGZB 4LRBA 4CYSA 5EGEA 2XRGA 3LXQA 3IGYB 3Q3QA 3WBHA 1URAA 3MK0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ANJ A;  1Y6V A;  2W5Q A;  1ED9 A;  1KH9 A;  4LR7 A;  3A52 A;  4CYR A;  2X98 A;  4LR8 A;  3BDH A;  3MK1 A;  4UPL A;  4CXK A;  5KXA A;  3BDF A;  5IJQ A;  4ZG9 A;  3WAV A;  5IJS A;  2W5X A;  2W5W A;  4GTX A;  3DPC A;  2XR9 A;  1KH7 A;  5L0K A;  5TJ3 A;  4ZG6 A;  1SHN A;  2W5V A;  2D1G A;  4UPI A;  5AJ9 A;  4KJG A;  2RH6 A;  3ED4 A;  1URB A;  3KD8 A;  3T02 A;  4LRC A;  2G9Y A;  1N2L A;  1AJC A;  3NKP A;  1AJD A;  3SZZ A;  4KAY A;  4CXU A;  3UNY A;  4ZG7 A;  5EGH A;  5K4P A;  1EW9 A;  4LRF A;  2W8D A;  3BDG B;  1HQA A;  3BDG A;  3TWZ A;  1ED8 A;  3E2D A;  3NKO A;  5LRM A;  3NKM A;  5INH A;  1ZED A;  5HRT A;  1EJJ A;  1O99 A;  3UO0 A;  3MK2 A;  1KHK A;  1ANI A;  4TN0 A;  5GRR A;  4ZGA A;  1B8J A;  4GTW A;  4FDI A;  1HDH A;  5LIA A;  3B5Q A;  4LQY A;  4UPH A;  4KM4 A;  3T01 A;  5L0B A;  4UOO A;  5L0E A;  4GTY A;  2GA3 A;  2GSO A;  1EQJ A;  1KH4 A;  3DYC A;  4N7T A;  1ALI A;  2QZU A;  1ELY A;  2W5R A;  2ZKT A;  4YR1 A;  1ZEB A;  2ANH A;  4KJD A;  3SZY A;  2IUC B;  1E3C P;  4LRA A;  2IUC A;  2GSN A;  1E1Z P;  1P49 A;  4UOP A;  5DLT A;  3UN3 A;  3NKQ A;  4GTZ A;  3UN2 A;  3WAY A;  1E2S P;  3TG0 A;  5DLW A;  5DLV A;  1ALK A;  4MY4 A;  1EI6 A;  2W8S A;  4B56 A;  1AUK A;  1O98 A;  3M8Z A;  1SHQ A;  1E33 P;  1KH5 A;  4KAV A;  3WAW A;  4MHX A;  1ZEF A;  5LQQ A;  1N2K A;  1KHJ A;  3NKR A;  4NWJ A;  1ALJ A;  2W5T A;  3WAX A;  1K7H A;  1EW2 A;  4FDJ A;  1KHN A;  1AJB A;  4MIV A;  1FSU A;  5GOV A;  1AJA A;  2GLQ A;  3M7V A;  2W5S A;  3M8W A;  4LRE A;  4UOR A;  4LRD A;  5C66 A;  5LRN A;  3NKN A;  1EW8 A;  4CXS A;  3T00 A;  2VQR A;  1HJK A;  3IDD A;  4QAX A;  2GSU A;  4NWX A;  1ELZ A;  4LR9 A;  3M8Y A;  1ALH A;  1ELX A;  1KHL A;  4UPK A;  2IFY A;  3OT9 A;  3CMR A;  3NVL A;  3UN5 A;  1Y7A A;  4LR2 A;  3TX0 A;  3IGZ B;  4LRB A;  4CYS A;  5EGE A;  2XRG A;  3LXQ A;  3IGY B;  3Q3Q A;  3WBH A;  1URA A;  3MK0 A; 
#chains in the Genus database with same CATH topology
 1ANJ A;  1Y6V A;  2W5Q A;  1ED9 A;  1KH9 A;  4LR7 A;  3A52 A;  4CYR A;  2X98 A;  4LR8 A;  3BDH A;  3MK1 A;  4UPL A;  4CXK A;  5KXA A;  3BDF A;  5IJQ A;  4ZG9 A;  3WAV A;  5IJS A;  2W5X A;  2W5W A;  4GTX A;  3DPC A;  2XR9 A;  1KH7 A;  5L0K A;  5TJ3 A;  4ZG6 A;  1SHN A;  2W5V A;  2D1G A;  4UPI A;  5AJ9 A;  4KJG A;  2RH6 A;  3ED4 A;  1URB A;  3KD8 A;  3T02 A;  4LRC A;  2G9Y A;  1N2L A;  1AJC A;  3NKP A;  1AJD A;  3SZZ A;  4KAY A;  4CXU A;  3UNY A;  4ZG7 A;  5EGH A;  5K4P A;  1EW9 A;  4LRF A;  2W8D A;  3BDG B;  1HQA A;  3BDG A;  3TWZ A;  1ED8 A;  3E2D A;  3NKO A;  5LRM A;  3NKM A;  5INH A;  1ZED A;  5HRT A;  1EJJ A;  1O99 A;  3UO0 A;  3MK2 A;  1KHK A;  1ANI A;  4TN0 A;  5GRR A;  4ZGA A;  1B8J A;  4GTW A;  4FDI A;  1HDH A;  5LIA A;  3B5Q A;  4LQY A;  4UPH A;  4KM4 A;  3T01 A;  5L0B A;  4UOO A;  5L0E A;  4GTY A;  2GA3 A;  2GSO A;  1EQJ A;  1KH4 A;  3DYC A;  4N7T A;  1ALI A;  2QZU A;  1ELY A;  2W5R A;  2ZKT A;  4YR1 A;  1ZEB A;  2ANH A;  4KJD A;  3SZY A;  2IUC B;  1E3C P;  4LRA A;  2IUC A;  2GSN A;  1E1Z P;  1P49 A;  4UOP A;  5DLT A;  3UN3 A;  3NKQ A;  4GTZ A;  3UN2 A;  3WAY A;  1E2S P;  3TG0 A;  5DLW A;  5DLV A;  1ALK A;  4MY4 A;  1EI6 A;  2W8S A;  4B56 A;  1AUK A;  1O98 A;  3M8Z A;  1SHQ A;  1E33 P;  1KH5 A;  4KAV A;  3WAW A;  4MHX A;  1ZEF A;  5LQQ A;  1N2K A;  1KHJ A;  3NKR A;  4NWJ A;  1ALJ A;  2W5T A;  3WAX A;  1K7H A;  1EW2 A;  4FDJ A;  1KHN A;  1AJB A;  4MIV A;  1FSU A;  5GOV A;  1AJA A;  2GLQ A;  3M7V A;  2W5S A;  3M8W A;  4LRE A;  4UOR A;  4LRD A;  5C66 A;  5LRN A;  3NKN A;  1EW8 A;  4CXS A;  3T00 A;  2VQR A;  1HJK A;  3IDD A;  4QAX A;  2GSU A;  4NWX A;  1ELZ A;  4LR9 A;  3M8Y A;  1ALH A;  1ELX A;  1KHL A;  4UPK A;  2IFY A;  3OT9 A;  3CMR A;  3NVL A;  3UN5 A;  1Y7A A;  4LR2 A;  3TX0 A;  3IGZ B;  4LRB A;  4CYS A;  5EGE A;  2XRG A;  3LXQ A;  3IGY B;  3Q3Q A;  3WBH A;  1URA A;  3MK0 A; 
#chains in the Genus database with same CATH homology
 1ANJ A;  1Y6V A;  2W5Q A;  1ED9 A;  1KH9 A;  4LR7 A;  3A52 A;  4CYR A;  2X98 A;  4LR8 A;  3BDH A;  3MK1 A;  4UPL A;  4CXK A;  5KXA A;  3BDF A;  5IJQ A;  4ZG9 A;  3WAV A;  5IJS A;  2W5X A;  2W5W A;  4GTX A;  3DPC A;  2XR9 A;  1KH7 A;  5L0K A;  5TJ3 A;  4ZG6 A;  1SHN A;  2W5V A;  2D1G A;  4UPI A;  5AJ9 A;  4KJG A;  2RH6 A;  3ED4 A;  1URB A;  3KD8 A;  3T02 A;  4LRC A;  2G9Y A;  1N2L A;  1AJC A;  3NKP A;  1AJD A;  3SZZ A;  4KAY A;  4CXU A;  3UNY A;  4ZG7 A;  5EGH A;  5K4P A;  1EW9 A;  4LRF A;  2W8D A;  3BDG B;  1HQA A;  3BDG A;  3TWZ A;  1ED8 A;  3E2D A;  3NKO A;  5LRM A;  3NKM A;  5INH A;  1ZED A;  5HRT A;  1EJJ A;  1O99 A;  3UO0 A;  3MK2 A;  1KHK A;  1ANI A;  4TN0 A;  5GRR A;  4ZGA A;  1B8J A;  4GTW A;  4FDI A;  1HDH A;  5LIA A;  3B5Q A;  4LQY A;  4UPH A;  4KM4 A;  3T01 A;  5L0B A;  4UOO A;  5L0E A;  4GTY A;  2GA3 A;  2GSO A;  1EQJ A;  1KH4 A;  3DYC A;  4N7T A;  1ALI A;  2QZU A;  1ELY A;  2W5R A;  2ZKT A;  4YR1 A;  1ZEB A;  2ANH A;  4KJD A;  3SZY A;  2IUC B;  1E3C P;  4LRA A;  2IUC A;  2GSN A;  1E1Z P;  1P49 A;  4UOP A;  5DLT A;  3UN3 A;  3NKQ A;  4GTZ A;  3UN2 A;  3WAY A;  1E2S P;  3TG0 A;  5DLW A;  5DLV A;  1ALK A;  4MY4 A;  1EI6 A;  2W8S A;  4B56 A;  1AUK A;  1O98 A;  3M8Z A;  1SHQ A;  1E33 P;  1KH5 A;  4KAV A;  3WAW A;  4MHX A;  1ZEF A;  5LQQ A;  1N2K A;  1KHJ A;  3NKR A;  4NWJ A;  1ALJ A;  2W5T A;  3WAX A;  1K7H A;  1EW2 A;  4FDJ A;  1KHN A;  1AJB A;  4MIV A;  1FSU A;  5GOV A;  1AJA A;  2GLQ A;  3M7V A;  2W5S A;  3M8W A;  4LRE A;  4UOR A;  4LRD A;  5C66 A;  5LRN A;  3NKN A;  1EW8 A;  4CXS A;  3T00 A;  2VQR A;  1HJK A;  3IDD A;  4QAX A;  2GSU A;  4NWX A;  1ELZ A;  4LR9 A;  3M8Y A;  1ALH A;  1ELX A;  1KHL A;  4UPK A;  2IFY A;  3OT9 A;  3CMR A;  3NVL A;  3UN5 A;  1Y7A A;  4LR2 A;  3TX0 A;  3IGZ B;  4LRB A;  4CYS A;  5EGE A;  2XRG A;  3LXQ A;  3IGY B;  3Q3Q A;  3WBH A;  1URA A;  3MK0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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