1SHNA

Crystal structure of shrimp alkaline phosphatase with phosphate bound
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords alkaline phosphatase
publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shnA00
1EQJA 3DYCA 4LR2A 2W5RA 3NKRA 3BDGA 1EW9A 4MIVA 3NKOA 3NKPA 3OT9A 4MHXA 4LQYA 3M8ZA 5EGHA 4CYSA 5LRNA 3NKMA 4UPIA 1Y7AA 1ALHA 2ANHA 4LRDA 3M8WA 4CXKA 2ZKTA 5DLTA 1SHQA 2IFYA 3SZYA 4LRFA 1ANIA 1URAA 2IUCB 1FSUA 3A52A 2W5VA 1B8JA 3TX0A 1EI6A 2G9YA 4YR1A 1ALKA 2XR9A 1ALJA 3TG0A 4ZGAA 4KM4A 4KJDA 3CMRA 5LQQA 1AJCA 1KHNA 1EJJA 2W5XA 4GTXA 1O98A 1SHNA 4GTZA 4CYRA 3UNYA 3T02A 4UPLA 1P49A 2GLQA 1ELZA 1O99A 3IDDA 4LRCA 1ELYA 4CXSA 5HRTA 4LRAA 3IGYB 3WAVA 4ZG7A 1HQAA 3MK2A 4GTYA 1ZEBA 4UORA 5INHA 1N2LA 2W5SA 3LXQA 1KHKA 4QAXA 4KAVA 4ZG6A 3IGZB 5DLVA 3T00A 2W5TA 1HDHA 1E1ZP 3WAWA 4UOOA 1KH7A 4UPHA 3TWZA 1AUKA 1KH5A 4FDJA 1Y6VA 3BDGB 4GTWA 3NKQA 4FDIA 2D1GA 3DPCA 4LREA 4LR8A 2GSOA 1K7HA 3BDFA 5L0BA 2W5WA 3M8YA 3MK0A 1KHLA 4UPKA 1KH9A 5C66A 1ZEDA 1EW8A 3NVLA 2QZUA 5LIAA 3B5QA 1AJAA 1ALIA 5LRMA 4LR9A 2IUCA 1E3CP 4LRBA 1EW2A 4TN0A 3UN5A 1N2KA 3BDHA 4MY4A 2XRGA 1ED8A 2VQRA 3MK1A 1KH4A 3T01A 3E2DA 5KXAA 3Q3QA 3UN2A 4UOPA 3NKNA 1KHJA 3UN3A 1AJDA 3SZZA 1ED9A 2GA3A 1URBA 2W8SA 4B56A 3WBHA 1HJKA 4N7TA 2RH6A 4KJGA 2X98A 4LR7A 5IJSA 3ED4A 1AJBA 1ANJA 4NWXA 5IJQA 2W8DA 4ZG9A 3WAYA 3M7VA 5GRRA 5L0KA 3KD8A 3UO0A 4NWJA 2GSNA 4CXUA 5K4PA 5TJ3A 4KAYA 5DLWA 5L0EA 2GSUA 3WAXA 5GOVA 1ZEFA 1E33P 5AJ9A 5EGEA 2W5QA 1ELXA 1E2SP
chains in the Genus database with same CATH superfamily
1EQJA 3DYCA 4LR2A 2W5RA 3NKRA 3BDGA 1EW9A 4MIVA 3NKOA 3NKPA 3OT9A 4MHXA 4LQYA 3M8ZA 5EGHA 4CYSA 5LRNA 3NKMA 4UPIA 1Y7AA 1ALHA 2ANHA 4LRDA 3M8WA 4CXKA 2ZKTA 5DLTA 1SHQA 2IFYA 3SZYA 4LRFA 1ANIA 1URAA 2IUCB 1FSUA 3A52A 2W5VA 1B8JA 3TX0A 1EI6A 2G9YA 4YR1A 1ALKA 2XR9A 1ALJA 3TG0A 4ZGAA 4KM4A 4KJDA 3CMRA 5LQQA 1AJCA 1KHNA 1EJJA 2W5XA 4GTXA 1O98A 1SHNA 4GTZA 4CYRA 3UNYA 3T02A 4UPLA 1P49A 2GLQA 1ELZA 1O99A 3IDDA 4LRCA 1ELYA 4CXSA 5HRTA 4LRAA 3IGYB 3WAVA 4ZG7A 1HQAA 3MK2A 4GTYA 1ZEBA 4UORA 5INHA 1N2LA 2W5SA 3LXQA 1KHKA 4QAXA 4KAVA 4ZG6A 3IGZB 5DLVA 3T00A 2W5TA 1HDHA 1E1ZP 3WAWA 4UOOA 1KH7A 4UPHA 3TWZA 1AUKA 1KH5A 4FDJA 1Y6VA 3BDGB 4GTWA 3NKQA 4FDIA 2D1GA 3DPCA 4LREA 4LR8A 2GSOA 1K7HA 3BDFA 5L0BA 2W5WA 3M8YA 3MK0A 1KHLA 4UPKA 1KH9A 5C66A 1ZEDA 1EW8A 3NVLA 2QZUA 5LIAA 3B5QA 1AJAA 1ALIA 5LRMA 4LR9A 2IUCA 1E3CP 4LRBA 1EW2A 4TN0A 3UN5A 1N2KA 3BDHA 4MY4A 2XRGA 1ED8A 2VQRA 3MK1A 1KH4A 3T01A 3E2DA 5KXAA 3Q3QA 3UN2A 4UOPA 3NKNA 1KHJA 3UN3A 1AJDA 3SZZA 1ED9A 2GA3A 1URBA 2W8SA 4B56A 3WBHA 1HJKA 4N7TA 2RH6A 4KJGA 2X98A 4LR7A 5IJSA 3ED4A 1AJBA 1ANJA 4NWXA 5IJQA 2W8DA 4ZG9A 3WAYA 3M7VA 5GRRA 5L0KA 3KD8A 3UO0A 4NWJA 2GSNA 4CXUA 5K4PA 5TJ3A 4KAYA 5DLWA 5L0EA 2GSUA 3WAXA 5GOVA 1ZEFA 1E33P 5AJ9A 5EGEA 2W5QA 1ELXA 1E2SP
chains in the Genus database with same CATH topology
1EQJA 3DYCA 4LR2A 2W5RA 3NKRA 3BDGA 1EW9A 4MIVA 3NKOA 3NKPA 3OT9A 4MHXA 4LQYA 3M8ZA 5EGHA 4CYSA 5LRNA 3NKMA 4UPIA 1Y7AA 1ALHA 2ANHA 4LRDA 3M8WA 4CXKA 2ZKTA 5DLTA 1SHQA 2IFYA 3SZYA 4LRFA 1ANIA 1URAA 2IUCB 1FSUA 3A52A 2W5VA 1B8JA 3TX0A 1EI6A 2G9YA 4YR1A 1ALKA 2XR9A 1ALJA 3TG0A 4ZGAA 4KM4A 4KJDA 3CMRA 5LQQA 1AJCA 1KHNA 1EJJA 2W5XA 4GTXA 1O98A 1SHNA 4GTZA 4CYRA 3UNYA 3T02A 4UPLA 1P49A 2GLQA 1ELZA 1O99A 3IDDA 4LRCA 1ELYA 4CXSA 5HRTA 4LRAA 3IGYB 3WAVA 4ZG7A 1HQAA 3MK2A 4GTYA 1ZEBA 4UORA 5INHA 1N2LA 2W5SA 3LXQA 1KHKA 4QAXA 4KAVA 4ZG6A 3IGZB 5DLVA 3T00A 2W5TA 1HDHA 1E1ZP 3WAWA 4UOOA 1KH7A 4UPHA 3TWZA 1AUKA 1KH5A 4FDJA 1Y6VA 3BDGB 4GTWA 3NKQA 4FDIA 2D1GA 3DPCA 4LREA 4LR8A 2GSOA 1K7HA 3BDFA 5L0BA 2W5WA 3M8YA 3MK0A 1KHLA 4UPKA 1KH9A 5C66A 1ZEDA 1EW8A 3NVLA 2QZUA 5LIAA 3B5QA 1AJAA 1ALIA 5LRMA 4LR9A 2IUCA 1E3CP 4LRBA 1EW2A 4TN0A 3UN5A 1N2KA 3BDHA 4MY4A 2XRGA 1ED8A 2VQRA 3MK1A 1KH4A 3T01A 3E2DA 5KXAA 3Q3QA 3UN2A 4UOPA 3NKNA 1KHJA 3UN3A 1AJDA 3SZZA 1ED9A 2GA3A 1URBA 2W8SA 4B56A 3WBHA 1HJKA 4N7TA 2RH6A 4KJGA 2X98A 4LR7A 5IJSA 3ED4A 1AJBA 1ANJA 4NWXA 5IJQA 2W8DA 4ZG9A 3WAYA 3M7VA 5GRRA 5L0KA 3KD8A 3UO0A 4NWJA 2GSNA 4CXUA 5K4PA 5TJ3A 4KAYA 5DLWA 5L0EA 2GSUA 3WAXA 5GOVA 1ZEFA 1E33P 5AJ9A 5EGEA 2W5QA 1ELXA 1E2SP
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EQJ A;  3DYC A;  4LR2 A;  2W5R A;  3NKR A;  3BDG A;  1EW9 A;  4MIV A;  3NKO A;  3NKP A;  3OT9 A;  4MHX A;  4LQY A;  3M8Z A;  5EGH A;  4CYS A;  5LRN A;  3NKM A;  4UPI A;  1Y7A A;  1ALH A;  2ANH A;  4LRD A;  3M8W A;  4CXK A;  2ZKT A;  5DLT A;  1SHQ A;  2IFY A;  3SZY A;  4LRF A;  1ANI A;  1URA A;  2IUC B;  1FSU A;  3A52 A;  2W5V A;  1B8J A;  3TX0 A;  1EI6 A;  2G9Y A;  4YR1 A;  1ALK A;  2XR9 A;  1ALJ A;  3TG0 A;  4ZGA A;  4KM4 A;  4KJD A;  3CMR A;  5LQQ A;  1AJC A;  1KHN A;  1EJJ A;  2W5X A;  4GTX A;  1O98 A;  1SHN A;  4GTZ A;  4CYR A;  3UNY A;  3T02 A;  4UPL A;  1P49 A;  2GLQ A;  1ELZ A;  1O99 A;  3IDD A;  4LRC A;  1ELY A;  4CXS A;  5HRT A;  4LRA A;  3IGY B;  3WAV A;  4ZG7 A;  1HQA A;  3MK2 A;  4GTY A;  1ZEB A;  4UOR A;  5INH A;  1N2L A;  2W5S A;  3LXQ A;  1KHK A;  4QAX A;  4KAV A;  4ZG6 A;  3IGZ B;  5DLV A;  3T00 A;  2W5T A;  1HDH A;  1E1Z P;  3WAW A;  4UOO A;  1KH7 A;  4UPH A;  3TWZ A;  1AUK A;  1KH5 A;  4FDJ A;  1Y6V A;  3BDG B;  4GTW A;  3NKQ A;  4FDI A;  2D1G A;  3DPC A;  4LRE A;  4LR8 A;  2GSO A;  1K7H A;  3BDF A;  5L0B A;  2W5W A;  3M8Y A;  3MK0 A;  1KHL A;  4UPK A;  1KH9 A;  5C66 A;  1ZED A;  1EW8 A;  3NVL A;  2QZU A;  5LIA A;  3B5Q A;  1AJA A;  1ALI A;  5LRM A;  4LR9 A;  2IUC A;  1E3C P;  4LRB A;  1EW2 A;  4TN0 A;  3UN5 A;  1N2K A;  3BDH A;  4MY4 A;  2XRG A;  1ED8 A;  2VQR A;  3MK1 A;  1KH4 A;  3T01 A;  3E2D A;  5KXA A;  3Q3Q A;  3UN2 A;  4UOP A;  3NKN A;  1KHJ A;  3UN3 A;  1AJD A;  3SZZ A;  1ED9 A;  2GA3 A;  1URB A;  2W8S A;  4B56 A;  3WBH A;  1HJK A;  4N7T A;  2RH6 A;  4KJG A;  2X98 A;  4LR7 A;  5IJS A;  3ED4 A;  1AJB A;  1ANJ A;  4NWX A;  5IJQ A;  2W8D A;  4ZG9 A;  3WAY A;  3M7V A;  5GRR A;  5L0K A;  3KD8 A;  3UO0 A;  4NWJ A;  2GSN A;  4CXU A;  5K4P A;  5TJ3 A;  4KAY A;  5DLW A;  5L0E A;  2GSU A;  3WAX A;  5GOV A;  1ZEF A;  1E33 P;  5AJ9 A;  5EGE A;  2W5Q A;  1ELX A;  1E2S P; 
#chains in the Genus database with same CATH topology
 1EQJ A;  3DYC A;  4LR2 A;  2W5R A;  3NKR A;  3BDG A;  1EW9 A;  4MIV A;  3NKO A;  3NKP A;  3OT9 A;  4MHX A;  4LQY A;  3M8Z A;  5EGH A;  4CYS A;  5LRN A;  3NKM A;  4UPI A;  1Y7A A;  1ALH A;  2ANH A;  4LRD A;  3M8W A;  4CXK A;  2ZKT A;  5DLT A;  1SHQ A;  2IFY A;  3SZY A;  4LRF A;  1ANI A;  1URA A;  2IUC B;  1FSU A;  3A52 A;  2W5V A;  1B8J A;  3TX0 A;  1EI6 A;  2G9Y A;  4YR1 A;  1ALK A;  2XR9 A;  1ALJ A;  3TG0 A;  4ZGA A;  4KM4 A;  4KJD A;  3CMR A;  5LQQ A;  1AJC A;  1KHN A;  1EJJ A;  2W5X A;  4GTX A;  1O98 A;  1SHN A;  4GTZ A;  4CYR A;  3UNY A;  3T02 A;  4UPL A;  1P49 A;  2GLQ A;  1ELZ A;  1O99 A;  3IDD A;  4LRC A;  1ELY A;  4CXS A;  5HRT A;  4LRA A;  3IGY B;  3WAV A;  4ZG7 A;  1HQA A;  3MK2 A;  4GTY A;  1ZEB A;  4UOR A;  5INH A;  1N2L A;  2W5S A;  3LXQ A;  1KHK A;  4QAX A;  4KAV A;  4ZG6 A;  3IGZ B;  5DLV A;  3T00 A;  2W5T A;  1HDH A;  1E1Z P;  3WAW A;  4UOO A;  1KH7 A;  4UPH A;  3TWZ A;  1AUK A;  1KH5 A;  4FDJ A;  1Y6V A;  3BDG B;  4GTW A;  3NKQ A;  4FDI A;  2D1G A;  3DPC A;  4LRE A;  4LR8 A;  2GSO A;  1K7H A;  3BDF A;  5L0B A;  2W5W A;  3M8Y A;  3MK0 A;  1KHL A;  4UPK A;  1KH9 A;  5C66 A;  1ZED A;  1EW8 A;  3NVL A;  2QZU A;  5LIA A;  3B5Q A;  1AJA A;  1ALI A;  5LRM A;  4LR9 A;  2IUC A;  1E3C P;  4LRB A;  1EW2 A;  4TN0 A;  3UN5 A;  1N2K A;  3BDH A;  4MY4 A;  2XRG A;  1ED8 A;  2VQR A;  3MK1 A;  1KH4 A;  3T01 A;  3E2D A;  5KXA A;  3Q3Q A;  3UN2 A;  4UOP A;  3NKN A;  1KHJ A;  3UN3 A;  1AJD A;  3SZZ A;  1ED9 A;  2GA3 A;  1URB A;  2W8S A;  4B56 A;  3WBH A;  1HJK A;  4N7T A;  2RH6 A;  4KJG A;  2X98 A;  4LR7 A;  5IJS A;  3ED4 A;  1AJB A;  1ANJ A;  4NWX A;  5IJQ A;  2W8D A;  4ZG9 A;  3WAY A;  3M7V A;  5GRR A;  5L0K A;  3KD8 A;  3UO0 A;  4NWJ A;  2GSN A;  4CXU A;  5K4P A;  5TJ3 A;  4KAY A;  5DLW A;  5L0E A;  2GSU A;  3WAX A;  5GOV A;  1ZEF A;  1E33 P;  5AJ9 A;  5EGE A;  2W5Q A;  1ELX A;  1E2S P; 
#chains in the Genus database with same CATH homology
 1EQJ A;  3DYC A;  4LR2 A;  2W5R A;  3NKR A;  3BDG A;  1EW9 A;  4MIV A;  3NKO A;  3NKP A;  3OT9 A;  4MHX A;  4LQY A;  3M8Z A;  5EGH A;  4CYS A;  5LRN A;  3NKM A;  4UPI A;  1Y7A A;  1ALH A;  2ANH A;  4LRD A;  3M8W A;  4CXK A;  2ZKT A;  5DLT A;  1SHQ A;  2IFY A;  3SZY A;  4LRF A;  1ANI A;  1URA A;  2IUC B;  1FSU A;  3A52 A;  2W5V A;  1B8J A;  3TX0 A;  1EI6 A;  2G9Y A;  4YR1 A;  1ALK A;  2XR9 A;  1ALJ A;  3TG0 A;  4ZGA A;  4KM4 A;  4KJD A;  3CMR A;  5LQQ A;  1AJC A;  1KHN A;  1EJJ A;  2W5X A;  4GTX A;  1O98 A;  1SHN A;  4GTZ A;  4CYR A;  3UNY A;  3T02 A;  4UPL A;  1P49 A;  2GLQ A;  1ELZ A;  1O99 A;  3IDD A;  4LRC A;  1ELY A;  4CXS A;  5HRT A;  4LRA A;  3IGY B;  3WAV A;  4ZG7 A;  1HQA A;  3MK2 A;  4GTY A;  1ZEB A;  4UOR A;  5INH A;  1N2L A;  2W5S A;  3LXQ A;  1KHK A;  4QAX A;  4KAV A;  4ZG6 A;  3IGZ B;  5DLV A;  3T00 A;  2W5T A;  1HDH A;  1E1Z P;  3WAW A;  4UOO A;  1KH7 A;  4UPH A;  3TWZ A;  1AUK A;  1KH5 A;  4FDJ A;  1Y6V A;  3BDG B;  4GTW A;  3NKQ A;  4FDI A;  2D1G A;  3DPC A;  4LRE A;  4LR8 A;  2GSO A;  1K7H A;  3BDF A;  5L0B A;  2W5W A;  3M8Y A;  3MK0 A;  1KHL A;  4UPK A;  1KH9 A;  5C66 A;  1ZED A;  1EW8 A;  3NVL A;  2QZU A;  5LIA A;  3B5Q A;  1AJA A;  1ALI A;  5LRM A;  4LR9 A;  2IUC A;  1E3C P;  4LRB A;  1EW2 A;  4TN0 A;  3UN5 A;  1N2K A;  3BDH A;  4MY4 A;  2XRG A;  1ED8 A;  2VQR A;  3MK1 A;  1KH4 A;  3T01 A;  3E2D A;  5KXA A;  3Q3Q A;  3UN2 A;  4UOP A;  3NKN A;  1KHJ A;  3UN3 A;  1AJD A;  3SZZ A;  1ED9 A;  2GA3 A;  1URB A;  2W8S A;  4B56 A;  3WBH A;  1HJK A;  4N7T A;  2RH6 A;  4KJG A;  2X98 A;  4LR7 A;  5IJS A;  3ED4 A;  1AJB A;  1ANJ A;  4NWX A;  5IJQ A;  2W8D A;  4ZG9 A;  3WAY A;  3M7V A;  5GRR A;  5L0K A;  3KD8 A;  3UO0 A;  4NWJ A;  2GSN A;  4CXU A;  5K4P A;  5TJ3 A;  4KAY A;  5DLW A;  5L0E A;  2GSU A;  3WAX A;  5GOV A;  1ZEF A;  1E33 P;  5AJ9 A;  5EGE A;  2W5Q A;  1ELX A;  1E2S P; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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