1EQJ | Genus

Total Genus 192

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	192
Knots found	KnotProt 2.0: S +3₁
sequence length	508
structure length	508
Chain Sequence	KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Isomerase
source organism	Geobacillus stearothermophilus
publication title	Mechanism of catalysis of the cofactor-independent phosphoglycerate mutase from Bacillus stearothermophilus. Crystal structure of the complex with 2-phosphoglycerate. pubmed doi rcsb
molecule keywords	PHOSPHOGLYCERATE MUTASE
total genus	192
structure length	508
sequence length	508
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date	2000-04-05

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01676	Metalloenzyme	Metalloenzyme superfamily
A	PF06415	iPGM_N	BPG-independent PGAM N-terminus (iPGM_N)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	1eqjA02
3.40.1450.10	Alpha Beta	3-Layer(aba) Sandwich	2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	BPG-independent phosphoglycerate mutase, domain B	1eqjA01

4GTZA 1AJAA 3WBHA 3SZZA 1EW2A 4B56A 3CMRA 1O99A 3NKRA 1KH9A 4YR1A 1SHQA 5L0EA 2GA3A 5DLWA 3DPCA 1EW8A 3IDDA 5K4PA 3BDFA 3NKPA 5GOVA 1AJDA 4LRDA 1EW9A 2QZUA 2XRGA 4ZGAA 3A52A 1KH7A 2W8SA 4LR7A 3M8WA 4LRBA 5AJ9A 3NVLA 4GTXA 1K7HA 1KHKA 4MIVA 4NWXA 4UPHA 1URAA 1KHLA 3B5QA 3BDGA 2IUCB 1E1ZP 1ANJA 1EQJA 4UPLA 1ELXA 5IJSA 2G9YA 4LREA 2W5XA 4QAXA 3Q3QA 1O98A 3ED4A 4LR9A 3T00A 5INHA 2ANHA 1ELZA 1AJCA 1E2SP 5LQQA 4N7TA 1KH5A 4LR8A 3WAYA 2W5TA 2X98A 4GTYA 4FDIA 3M8ZA 4UORA 3MK2A 3M8YA 4MHXA 5GRRA 4LRCA 3T02A 4CXUA 4LR2A 2IFYA 1E33P 3SZYA 5L0KA 3NKNA 2VQRA 4CYRA 1E3CP 4NWJA 5EGEA 3WAXA 1ALIA 4KAVA 1Y7AA 1HJKA 1AJBA 1ELYA 4TN0A 1ALHA 4KJGA 4ZG7A 3BDGB 5EGHA 1ED9A 3MK1A 2W5RA 4FDJA 3T01A 4KJDA 5DLTA 2W5VA 5TJ3A 5LIAA 3E2DA 2XR9A 3NKOA 2D1GA 4CXSA 1B8JA 4LQYA 3UN5A 4ZG6A 2GSOA 1N2LA 1ED8A 3UN2A 2W5WA 2GSNA 1ZEBA 1Y6VA 3BDHA 2ZKTA 5HRTA 1ANIA 4LRFA 3IGYB 4KM4A 2W5QA 1ALKA 3IGZB 1KHJA 5LRNA 4ZG9A 2W5SA 4UOPA 3TG0A 3LXQA 1ALJA 2W8DA 2GSUA 4GTWA 4MY4A 4UPIA 1KHNA 1HDHA 3WAWA 5LRMA 4UPKA 2RH6A 3DYCA 1KH4A 3MK0A 4KAYA 4LRAA 1EI6A 3NKQA 1HQAA 5L0BA 1N2KA 3WAVA 4UOOA 1ZEFA 3M7VA 4CYSA 5C66A 1SHNA 1FSUA 1AUKA 5DLVA 2IUCA 3OT9A 3UN3A 3KD8A 5KXAA 1URBA 5IJQA 3UNYA 4CXKA 3TWZA 3NKMA 3TX0A 1P49A 1ZEDA 1EJJA 2GLQA 3UO0A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4GTZ A;  1AJA A;  3WBH A;  3SZZ A;  1EW2 A;  4B56 A;  3CMR A;  1O99 A;  3NKR A;  1KH9 A;  4YR1 A;  1SHQ A;  5L0E A;  2GA3 A;  5DLW A;  3DPC A;  1EW8 A;  3IDD A;  5K4P A;  3BDF A;  3NKP A;  5GOV A;  1AJD A;  4LRD A;  1EW9 A;  2QZU A;  2XRG A;  4ZGA A;  3A52 A;  1KH7 A;  2W8S A;  4LR7 A;  3M8W A;  4LRB A;  5AJ9 A;  3NVL A;  4GTX A;  1K7H A;  1KHK A;  4MIV A;  4NWX A;  4UPH A;  1URA A;  1KHL A;  3B5Q A;  3BDG A;  2IUC B;  1E1Z P;  1ANJ A;  1EQJ A;  4UPL A;  1ELX A;  5IJS A;  2G9Y A;  4LRE A;  2W5X A;  4QAX A;  3Q3Q A;  1O98 A;  3ED4 A;  4LR9 A;  3T00 A;  5INH A;  2ANH A;  1ELZ A;  1AJC A;  1E2S P;  5LQQ A;  4N7T A;  1KH5 A;  4LR8 A;  3WAY A;  2W5T A;  2X98 A;  4GTY A;  4FDI A;  3M8Z A;  4UOR A;  3MK2 A;  3M8Y A;  4MHX A;  5GRR A;  4LRC A;  3T02 A;  4CXU A;  4LR2 A;  2IFY A;  1E33 P;  3SZY A;  5L0K A;  3NKN A;  2VQR A;  4CYR A;  1E3C P;  4NWJ A;  5EGE A;  3WAX A;  1ALI A;  4KAV A;  1Y7A A;  1HJK A;  1AJB A;  1ELY A;  4TN0 A;  1ALH A;  4KJG A;  4ZG7 A;  3BDG B;  5EGH A;  1ED9 A;  3MK1 A;  2W5R A;  4FDJ A;  3T01 A;  4KJD A;  5DLT A;  2W5V A;  5TJ3 A;  5LIA A;  3E2D A;  2XR9 A;  3NKO A;  2D1G A;  4CXS A;  1B8J A;  4LQY A;  3UN5 A;  4ZG6 A;  2GSO A;  1N2L A;  1ED8 A;  3UN2 A;  2W5W A;  2GSN A;  1ZEB A;  1Y6V A;  3BDH A;  2ZKT A;  5HRT A;  1ANI A;  4LRF A;  3IGY B;  4KM4 A;  2W5Q A;  1ALK A;  3IGZ B;  1KHJ A;  5LRN A;  4ZG9 A;  2W5S A;  4UOP A;  3TG0 A;  3LXQ A;  1ALJ A;  2W8D A;  2GSU A;  4GTW A;  4MY4 A;  4UPI A;  1KHN A;  1HDH A;  3WAW A;  5LRM A;  4UPK A;  2RH6 A;  3DYC A;  1KH4 A;  3MK0 A;  4KAY A;  4LRA A;  1EI6 A;  3NKQ A;  1HQA A;  5L0B A;  1N2K A;  3WAV A;  4UOO A;  1ZEF A;  3M7V A;  4CYS A;  5C66 A;  1SHN A;  1FSU A;  1AUK A;  5DLV A;  2IUC A;  3OT9 A;  3UN3 A;  3KD8 A;  5KXA A;  1URB A;  5IJQ A;  3UNY A;  4CXK A;  3TWZ A;  3NKM A;  3TX0 A;  1P49 A;  1ZED A;  1EJJ A;  2GLQ A;  3UO0 A; 
#chains in the Genus database with same CATH topology
 4GTZ A;  1AJA A;  3WBH A;  3SZZ A;  1EW2 A;  4B56 A;  3CMR A;  1O99 A;  3NKR A;  1KH9 A;  4YR1 A;  1SHQ A;  5L0E A;  2GA3 A;  5DLW A;  3DPC A;  1EW8 A;  3IDD A;  5K4P A;  3BDF A;  3NKP A;  5GOV A;  1AJD A;  4LRD A;  1EW9 A;  2QZU A;  2XRG A;  4ZGA A;  3A52 A;  1KH7 A;  2W8S A;  4LR7 A;  3M8W A;  4LRB A;  5AJ9 A;  3NVL A;  4GTX A;  1K7H A;  1KHK A;  4MIV A;  4NWX A;  4UPH A;  1URA A;  1KHL A;  3B5Q A;  3BDG A;  2IUC B;  1E1Z P;  1ANJ A;  1EQJ A;  4UPL A;  1ELX A;  5IJS A;  2G9Y A;  4LRE A;  2W5X A;  4QAX A;  3Q3Q A;  1O98 A;  3ED4 A;  4LR9 A;  3T00 A;  5INH A;  2ANH A;  1ELZ A;  1AJC A;  1E2S P;  5LQQ A;  4N7T A;  1KH5 A;  4LR8 A;  3WAY A;  2W5T A;  2X98 A;  4GTY A;  4FDI A;  3M8Z A;  4UOR A;  3MK2 A;  3M8Y A;  4MHX A;  5GRR A;  4LRC A;  3T02 A;  4CXU A;  4LR2 A;  2IFY A;  1E33 P;  3SZY A;  5L0K A;  3NKN A;  2VQR A;  4CYR A;  1E3C P;  4NWJ A;  5EGE A;  3WAX A;  1ALI A;  4KAV A;  1Y7A A;  1HJK A;  1AJB A;  1ELY A;  4TN0 A;  1ALH A;  4KJG A;  4ZG7 A;  3BDG B;  5EGH A;  1ED9 A;  3MK1 A;  2W5R A;  4FDJ A;  3T01 A;  4KJD A;  5DLT A;  2W5V A;  5TJ3 A;  5LIA A;  3E2D A;  2XR9 A;  3NKO A;  2D1G A;  4CXS A;  1B8J A;  4LQY A;  3UN5 A;  4ZG6 A;  2GSO A;  1N2L A;  1ED8 A;  3UN2 A;  2W5W A;  2GSN A;  1ZEB A;  1Y6V A;  3BDH A;  2ZKT A;  5HRT A;  1ANI A;  4LRF A;  3IGY B;  4KM4 A;  2W5Q A;  1ALK A;  3IGZ B;  1KHJ A;  5LRN A;  4ZG9 A;  2W5S A;  4UOP A;  3TG0 A;  3LXQ A;  1ALJ A;  2W8D A;  2GSU A;  4GTW A;  4MY4 A;  4UPI A;  1KHN A;  1HDH A;  3WAW A;  5LRM A;  4UPK A;  2RH6 A;  3DYC A;  1KH4 A;  3MK0 A;  4KAY A;  4LRA A;  1EI6 A;  3NKQ A;  1HQA A;  5L0B A;  1N2K A;  3WAV A;  4UOO A;  1ZEF A;  3M7V A;  4CYS A;  5C66 A;  1SHN A;  1FSU A;  1AUK A;  5DLV A;  2IUC A;  3OT9 A;  3UN3 A;  3KD8 A;  5KXA A;  1URB A;  5IJQ A;  3UNY A;  4CXK A;  3TWZ A;  3NKM A;  3TX0 A;  1P49 A;  1ZED A;  1EJJ A;  2GLQ A;  3UO0 A; 
#chains in the Genus database with same CATH homology
 4GTZ A;  1AJA A;  3WBH A;  3SZZ A;  1EW2 A;  4B56 A;  3CMR A;  1O99 A;  3NKR A;  1KH9 A;  4YR1 A;  1SHQ A;  5L0E A;  2GA3 A;  5DLW A;  3DPC A;  1EW8 A;  3IDD A;  5K4P A;  3BDF A;  3NKP A;  5GOV A;  1AJD A;  4LRD A;  1EW9 A;  2QZU A;  2XRG A;  4ZGA A;  3A52 A;  1KH7 A;  2W8S A;  4LR7 A;  3M8W A;  4LRB A;  5AJ9 A;  3NVL A;  4GTX A;  1K7H A;  1KHK A;  4MIV A;  4NWX A;  4UPH A;  1URA A;  1KHL A;  3B5Q A;  3BDG A;  2IUC B;  1E1Z P;  1ANJ A;  1EQJ A;  4UPL A;  1ELX A;  5IJS A;  2G9Y A;  4LRE A;  2W5X A;  4QAX A;  3Q3Q A;  1O98 A;  3ED4 A;  4LR9 A;  3T00 A;  5INH A;  2ANH A;  1ELZ A;  1AJC A;  1E2S P;  5LQQ A;  4N7T A;  1KH5 A;  4LR8 A;  3WAY A;  2W5T A;  2X98 A;  4GTY A;  4FDI A;  3M8Z A;  4UOR A;  3MK2 A;  3M8Y A;  4MHX A;  5GRR A;  4LRC A;  3T02 A;  4CXU A;  4LR2 A;  2IFY A;  1E33 P;  3SZY A;  5L0K A;  3NKN A;  2VQR A;  4CYR A;  1E3C P;  4NWJ A;  5EGE A;  3WAX A;  1ALI A;  4KAV A;  1Y7A A;  1HJK A;  1AJB A;  1ELY A;  4TN0 A;  1ALH A;  4KJG A;  4ZG7 A;  3BDG B;  5EGH A;  1ED9 A;  3MK1 A;  2W5R A;  4FDJ A;  3T01 A;  4KJD A;  5DLT A;  2W5V A;  5TJ3 A;  5LIA A;  3E2D A;  2XR9 A;  3NKO A;  2D1G A;  4CXS A;  1B8J A;  4LQY A;  3UN5 A;  4ZG6 A;  2GSO A;  1N2L A;  1ED8 A;  3UN2 A;  2W5W A;  2GSN A;  1ZEB A;  1Y6V A;  3BDH A;  2ZKT A;  5HRT A;  1ANI A;  4LRF A;  3IGY B;  4KM4 A;  2W5Q A;  1ALK A;  3IGZ B;  1KHJ A;  5LRN A;  4ZG9 A;  2W5S A;  4UOP A;  3TG0 A;  3LXQ A;  1ALJ A;  2W8D A;  2GSU A;  4GTW A;  4MY4 A;  4UPI A;  1KHN A;  1HDH A;  3WAW A;  5LRM A;  4UPK A;  2RH6 A;  3DYC A;  1KH4 A;  3MK0 A;  4KAY A;  4LRA A;  1EI6 A;  3NKQ A;  1HQA A;  5L0B A;  1N2K A;  3WAV A;  4UOO A;  1ZEF A;  3M7V A;  4CYS A;  5C66 A;  1SHN A;  1FSU A;  1AUK A;  5DLV A;  2IUC A;  3OT9 A;  3UN3 A;  3KD8 A;  5KXA A;  1URB A;  5IJQ A;  3UNY A;  4CXK A;  3TWZ A;  3NKM A;  3TX0 A;  1P49 A;  1ZED A;  1EJJ A;  2GLQ A;  3UO0 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1EQJA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations