1SHNA

Crystal structure of shrimp alkaline phosphatase with phosphate bound
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords alkaline phosphatase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shnA00
3SZYA 4CXSA 5TJ3A 5GRRA 4LR7A 3DYCA 5DLTA 3SZZA 1ANIA 3UO0A 1ED9A 1KH9A 3M7VA 1AJCA 1HQAA 2W8SA 2QZUA 1ZEBA 5DLWA 2W8DA 3WAVA 2W5VA 1ED8A 4LR8A 2IUCA 4KAVA 3BDGB 3NVLA 4GTZA 3E2DA 3UN3A 1KH7A 3MK0A 4LREA 4UPKA 4GTXA 4UPIA 2W5SA 1ALKA 2W5WA 4N7TA 1N2LA 1KHJA 4FDJA 4NWJA 4LR2A 3CMRA 5K4PA 3IGZB 3LXQA 1ELZA 3TX0A 1E33P 4GTWA 5HRTA 1EJJA 1O98A 4LR9A 1KHNA 3NKMA 2ZKTA 1AJDA 2RH6A 3WAWA 3TWZA 5IJSA 2W5TA 2X98A 3IGYB 3NKOA 3NKNA 4KJGA 5AJ9A 4UOOA 3BDGA 2VQRA 2W5XA 4QAXA 4UPLA 1N2KA 2W5QA 1HJKA 1K7HA 4KJDA 1URAA 3M8WA 4LRCA 3TG0A 5LQQA 1ELYA 1EW9A 5EGEA 4LRBA 3WBHA 3NKRA 5DLVA 1HDHA 4MIVA 1Y6VA 3OT9A 4LRFA 1KH5A 3UNYA 1AJAA 1SHNA 4LRAA 1EI6A 4ZG9A 4UORA 2IFYA 1ZEFA 3BDHA 3NKQA 1EW8A 1ZEDA 4NWXA 2ANHA 2GSUA 3UN5A 3NKPA 1KHKA 4MHXA 1SHQA 4ZGAA 4MY4A 3DPCA 4B56A 1B8JA 4ZG6A 4CXKA 3A52A 1URBA 5LRNA 1Y7AA 1ALHA 5IJQA 1ALIA 1E2SP 3WAYA 4CXUA 1O99A 2XRGA 4ZG7A 2GSOA 1KHLA 3M8YA 3WAXA 1EQJA 1FSUA 5INHA 1KH4A 5GOVA 3T02A 2XR9A 1EW2A 4LRDA 5LIAA 2GA3A 4GTYA 3B5QA 3T01A 1P49A 5LRMA 3BDFA 4FDIA 5KXAA 4KM4A 1ALJA 3UN2A 1AJBA 1ANJA 4CYRA 4UOPA 3T00A 2GLQA 2W5RA 3M8ZA 1E3CP 4TN0A 2GSNA 3KD8A 4UPHA 1ELXA 4YR1A 4CYSA 4LQYA 3MK1A 4KAYA 5EGHA 2IUCB 5L0EA 2D1GA 3ED4A 5L0KA 1E1ZP 3IDDA 2G9YA 5C66A 3MK2A 3Q3QA 5L0BA 1AUKA
chains in the Genus database with same CATH superfamily
3SZYA 4CXSA 5TJ3A 5GRRA 4LR7A 3DYCA 5DLTA 3SZZA 1ANIA 3UO0A 1ED9A 1KH9A 3M7VA 1AJCA 1HQAA 2W8SA 2QZUA 1ZEBA 5DLWA 2W8DA 3WAVA 2W5VA 1ED8A 4LR8A 2IUCA 4KAVA 3BDGB 3NVLA 4GTZA 3E2DA 3UN3A 1KH7A 3MK0A 4LREA 4UPKA 4GTXA 4UPIA 2W5SA 1ALKA 2W5WA 4N7TA 1N2LA 1KHJA 4FDJA 4NWJA 4LR2A 3CMRA 5K4PA 3IGZB 3LXQA 1ELZA 3TX0A 1E33P 4GTWA 5HRTA 1EJJA 1O98A 4LR9A 1KHNA 3NKMA 2ZKTA 1AJDA 2RH6A 3WAWA 3TWZA 5IJSA 2W5TA 2X98A 3IGYB 3NKOA 3NKNA 4KJGA 5AJ9A 4UOOA 3BDGA 2VQRA 2W5XA 4QAXA 4UPLA 1N2KA 2W5QA 1HJKA 1K7HA 4KJDA 1URAA 3M8WA 4LRCA 3TG0A 5LQQA 1ELYA 1EW9A 5EGEA 4LRBA 3WBHA 3NKRA 5DLVA 1HDHA 4MIVA 1Y6VA 3OT9A 4LRFA 1KH5A 3UNYA 1AJAA 1SHNA 4LRAA 1EI6A 4ZG9A 4UORA 2IFYA 1ZEFA 3BDHA 3NKQA 1EW8A 1ZEDA 4NWXA 2ANHA 2GSUA 3UN5A 3NKPA 1KHKA 4MHXA 1SHQA 4ZGAA 4MY4A 3DPCA 4B56A 1B8JA 4ZG6A 4CXKA 3A52A 1URBA 5LRNA 1Y7AA 1ALHA 5IJQA 1ALIA 1E2SP 3WAYA 4CXUA 1O99A 2XRGA 4ZG7A 2GSOA 1KHLA 3M8YA 3WAXA 1EQJA 1FSUA 5INHA 1KH4A 5GOVA 3T02A 2XR9A 1EW2A 4LRDA 5LIAA 2GA3A 4GTYA 3B5QA 3T01A 1P49A 5LRMA 3BDFA 4FDIA 5KXAA 4KM4A 1ALJA 3UN2A 1AJBA 1ANJA 4CYRA 4UOPA 3T00A 2GLQA 2W5RA 3M8ZA 1E3CP 4TN0A 2GSNA 3KD8A 4UPHA 1ELXA 4YR1A 4CYSA 4LQYA 3MK1A 4KAYA 5EGHA 2IUCB 5L0EA 2D1GA 3ED4A 5L0KA 1E1ZP 3IDDA 2G9YA 5C66A 3MK2A 3Q3QA 5L0BA 1AUKA
chains in the Genus database with same CATH topology
3SZYA 4CXSA 5TJ3A 5GRRA 4LR7A 3DYCA 5DLTA 3SZZA 1ANIA 3UO0A 1ED9A 1KH9A 3M7VA 1AJCA 1HQAA 2W8SA 2QZUA 1ZEBA 5DLWA 2W8DA 3WAVA 2W5VA 1ED8A 4LR8A 2IUCA 4KAVA 3BDGB 3NVLA 4GTZA 3E2DA 3UN3A 1KH7A 3MK0A 4LREA 4UPKA 4GTXA 4UPIA 2W5SA 1ALKA 2W5WA 4N7TA 1N2LA 1KHJA 4FDJA 4NWJA 4LR2A 3CMRA 5K4PA 3IGZB 3LXQA 1ELZA 3TX0A 1E33P 4GTWA 5HRTA 1EJJA 1O98A 4LR9A 1KHNA 3NKMA 2ZKTA 1AJDA 2RH6A 3WAWA 3TWZA 5IJSA 2W5TA 2X98A 3IGYB 3NKOA 3NKNA 4KJGA 5AJ9A 4UOOA 3BDGA 2VQRA 2W5XA 4QAXA 4UPLA 1N2KA 2W5QA 1HJKA 1K7HA 4KJDA 1URAA 3M8WA 4LRCA 3TG0A 5LQQA 1ELYA 1EW9A 5EGEA 4LRBA 3WBHA 3NKRA 5DLVA 1HDHA 4MIVA 1Y6VA 3OT9A 4LRFA 1KH5A 3UNYA 1AJAA 1SHNA 4LRAA 1EI6A 4ZG9A 4UORA 2IFYA 1ZEFA 3BDHA 3NKQA 1EW8A 1ZEDA 4NWXA 2ANHA 2GSUA 3UN5A 3NKPA 1KHKA 4MHXA 1SHQA 4ZGAA 4MY4A 3DPCA 4B56A 1B8JA 4ZG6A 4CXKA 3A52A 1URBA 5LRNA 1Y7AA 1ALHA 5IJQA 1ALIA 1E2SP 3WAYA 4CXUA 1O99A 2XRGA 4ZG7A 2GSOA 1KHLA 3M8YA 3WAXA 1EQJA 1FSUA 5INHA 1KH4A 5GOVA 3T02A 2XR9A 1EW2A 4LRDA 5LIAA 2GA3A 4GTYA 3B5QA 3T01A 1P49A 5LRMA 3BDFA 4FDIA 5KXAA 4KM4A 1ALJA 3UN2A 1AJBA 1ANJA 4CYRA 4UOPA 3T00A 2GLQA 2W5RA 3M8ZA 1E3CP 4TN0A 2GSNA 3KD8A 4UPHA 1ELXA 4YR1A 4CYSA 4LQYA 3MK1A 4KAYA 5EGHA 2IUCB 5L0EA 2D1GA 3ED4A 5L0KA 1E1ZP 3IDDA 2G9YA 5C66A 3MK2A 3Q3QA 5L0BA 1AUKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SZY A;  4CXS A;  5TJ3 A;  5GRR A;  4LR7 A;  3DYC A;  5DLT A;  3SZZ A;  1ANI A;  3UO0 A;  1ED9 A;  1KH9 A;  3M7V A;  1AJC A;  1HQA A;  2W8S A;  2QZU A;  1ZEB A;  5DLW A;  2W8D A;  3WAV A;  2W5V A;  1ED8 A;  4LR8 A;  2IUC A;  4KAV A;  3BDG B;  3NVL A;  4GTZ A;  3E2D A;  3UN3 A;  1KH7 A;  3MK0 A;  4LRE A;  4UPK A;  4GTX A;  4UPI A;  2W5S A;  1ALK A;  2W5W A;  4N7T A;  1N2L A;  1KHJ A;  4FDJ A;  4NWJ A;  4LR2 A;  3CMR A;  5K4P A;  3IGZ B;  3LXQ A;  1ELZ A;  3TX0 A;  1E33 P;  4GTW A;  5HRT A;  1EJJ A;  1O98 A;  4LR9 A;  1KHN A;  3NKM A;  2ZKT A;  1AJD A;  2RH6 A;  3WAW A;  3TWZ A;  5IJS A;  2W5T A;  2X98 A;  3IGY B;  3NKO A;  3NKN A;  4KJG A;  5AJ9 A;  4UOO A;  3BDG A;  2VQR A;  2W5X A;  4QAX A;  4UPL A;  1N2K A;  2W5Q A;  1HJK A;  1K7H A;  4KJD A;  1URA A;  3M8W A;  4LRC A;  3TG0 A;  5LQQ A;  1ELY A;  1EW9 A;  5EGE A;  4LRB A;  3WBH A;  3NKR A;  5DLV A;  1HDH A;  4MIV A;  1Y6V A;  3OT9 A;  4LRF A;  1KH5 A;  3UNY A;  1AJA A;  1SHN A;  4LRA A;  1EI6 A;  4ZG9 A;  4UOR A;  2IFY A;  1ZEF A;  3BDH A;  3NKQ A;  1EW8 A;  1ZED A;  4NWX A;  2ANH A;  2GSU A;  3UN5 A;  3NKP A;  1KHK A;  4MHX A;  1SHQ A;  4ZGA A;  4MY4 A;  3DPC A;  4B56 A;  1B8J A;  4ZG6 A;  4CXK A;  3A52 A;  1URB A;  5LRN A;  1Y7A A;  1ALH A;  5IJQ A;  1ALI A;  1E2S P;  3WAY A;  4CXU A;  1O99 A;  2XRG A;  4ZG7 A;  2GSO A;  1KHL A;  3M8Y A;  3WAX A;  1EQJ A;  1FSU A;  5INH A;  1KH4 A;  5GOV A;  3T02 A;  2XR9 A;  1EW2 A;  4LRD A;  5LIA A;  2GA3 A;  4GTY A;  3B5Q A;  3T01 A;  1P49 A;  5LRM A;  3BDF A;  4FDI A;  5KXA A;  4KM4 A;  1ALJ A;  3UN2 A;  1AJB A;  1ANJ A;  4CYR A;  4UOP A;  3T00 A;  2GLQ A;  2W5R A;  3M8Z A;  1E3C P;  4TN0 A;  2GSN A;  3KD8 A;  4UPH A;  1ELX A;  4YR1 A;  4CYS A;  4LQY A;  3MK1 A;  4KAY A;  5EGH A;  2IUC B;  5L0E A;  2D1G A;  3ED4 A;  5L0K A;  1E1Z P;  3IDD A;  2G9Y A;  5C66 A;  3MK2 A;  3Q3Q A;  5L0B A;  1AUK A; 
#chains in the Genus database with same CATH topology
 3SZY A;  4CXS A;  5TJ3 A;  5GRR A;  4LR7 A;  3DYC A;  5DLT A;  3SZZ A;  1ANI A;  3UO0 A;  1ED9 A;  1KH9 A;  3M7V A;  1AJC A;  1HQA A;  2W8S A;  2QZU A;  1ZEB A;  5DLW A;  2W8D A;  3WAV A;  2W5V A;  1ED8 A;  4LR8 A;  2IUC A;  4KAV A;  3BDG B;  3NVL A;  4GTZ A;  3E2D A;  3UN3 A;  1KH7 A;  3MK0 A;  4LRE A;  4UPK A;  4GTX A;  4UPI A;  2W5S A;  1ALK A;  2W5W A;  4N7T A;  1N2L A;  1KHJ A;  4FDJ A;  4NWJ A;  4LR2 A;  3CMR A;  5K4P A;  3IGZ B;  3LXQ A;  1ELZ A;  3TX0 A;  1E33 P;  4GTW A;  5HRT A;  1EJJ A;  1O98 A;  4LR9 A;  1KHN A;  3NKM A;  2ZKT A;  1AJD A;  2RH6 A;  3WAW A;  3TWZ A;  5IJS A;  2W5T A;  2X98 A;  3IGY B;  3NKO A;  3NKN A;  4KJG A;  5AJ9 A;  4UOO A;  3BDG A;  2VQR A;  2W5X A;  4QAX A;  4UPL A;  1N2K A;  2W5Q A;  1HJK A;  1K7H A;  4KJD A;  1URA A;  3M8W A;  4LRC A;  3TG0 A;  5LQQ A;  1ELY A;  1EW9 A;  5EGE A;  4LRB A;  3WBH A;  3NKR A;  5DLV A;  1HDH A;  4MIV A;  1Y6V A;  3OT9 A;  4LRF A;  1KH5 A;  3UNY A;  1AJA A;  1SHN A;  4LRA A;  1EI6 A;  4ZG9 A;  4UOR A;  2IFY A;  1ZEF A;  3BDH A;  3NKQ A;  1EW8 A;  1ZED A;  4NWX A;  2ANH A;  2GSU A;  3UN5 A;  3NKP A;  1KHK A;  4MHX A;  1SHQ A;  4ZGA A;  4MY4 A;  3DPC A;  4B56 A;  1B8J A;  4ZG6 A;  4CXK A;  3A52 A;  1URB A;  5LRN A;  1Y7A A;  1ALH A;  5IJQ A;  1ALI A;  1E2S P;  3WAY A;  4CXU A;  1O99 A;  2XRG A;  4ZG7 A;  2GSO A;  1KHL A;  3M8Y A;  3WAX A;  1EQJ A;  1FSU A;  5INH A;  1KH4 A;  5GOV A;  3T02 A;  2XR9 A;  1EW2 A;  4LRD A;  5LIA A;  2GA3 A;  4GTY A;  3B5Q A;  3T01 A;  1P49 A;  5LRM A;  3BDF A;  4FDI A;  5KXA A;  4KM4 A;  1ALJ A;  3UN2 A;  1AJB A;  1ANJ A;  4CYR A;  4UOP A;  3T00 A;  2GLQ A;  2W5R A;  3M8Z A;  1E3C P;  4TN0 A;  2GSN A;  3KD8 A;  4UPH A;  1ELX A;  4YR1 A;  4CYS A;  4LQY A;  3MK1 A;  4KAY A;  5EGH A;  2IUC B;  5L0E A;  2D1G A;  3ED4 A;  5L0K A;  1E1Z P;  3IDD A;  2G9Y A;  5C66 A;  3MK2 A;  3Q3Q A;  5L0B A;  1AUK A; 
#chains in the Genus database with same CATH homology
 3SZY A;  4CXS A;  5TJ3 A;  5GRR A;  4LR7 A;  3DYC A;  5DLT A;  3SZZ A;  1ANI A;  3UO0 A;  1ED9 A;  1KH9 A;  3M7V A;  1AJC A;  1HQA A;  2W8S A;  2QZU A;  1ZEB A;  5DLW A;  2W8D A;  3WAV A;  2W5V A;  1ED8 A;  4LR8 A;  2IUC A;  4KAV A;  3BDG B;  3NVL A;  4GTZ A;  3E2D A;  3UN3 A;  1KH7 A;  3MK0 A;  4LRE A;  4UPK A;  4GTX A;  4UPI A;  2W5S A;  1ALK A;  2W5W A;  4N7T A;  1N2L A;  1KHJ A;  4FDJ A;  4NWJ A;  4LR2 A;  3CMR A;  5K4P A;  3IGZ B;  3LXQ A;  1ELZ A;  3TX0 A;  1E33 P;  4GTW A;  5HRT A;  1EJJ A;  1O98 A;  4LR9 A;  1KHN A;  3NKM A;  2ZKT A;  1AJD A;  2RH6 A;  3WAW A;  3TWZ A;  5IJS A;  2W5T A;  2X98 A;  3IGY B;  3NKO A;  3NKN A;  4KJG A;  5AJ9 A;  4UOO A;  3BDG A;  2VQR A;  2W5X A;  4QAX A;  4UPL A;  1N2K A;  2W5Q A;  1HJK A;  1K7H A;  4KJD A;  1URA A;  3M8W A;  4LRC A;  3TG0 A;  5LQQ A;  1ELY A;  1EW9 A;  5EGE A;  4LRB A;  3WBH A;  3NKR A;  5DLV A;  1HDH A;  4MIV A;  1Y6V A;  3OT9 A;  4LRF A;  1KH5 A;  3UNY A;  1AJA A;  1SHN A;  4LRA A;  1EI6 A;  4ZG9 A;  4UOR A;  2IFY A;  1ZEF A;  3BDH A;  3NKQ A;  1EW8 A;  1ZED A;  4NWX A;  2ANH A;  2GSU A;  3UN5 A;  3NKP A;  1KHK A;  4MHX A;  1SHQ A;  4ZGA A;  4MY4 A;  3DPC A;  4B56 A;  1B8J A;  4ZG6 A;  4CXK A;  3A52 A;  1URB A;  5LRN A;  1Y7A A;  1ALH A;  5IJQ A;  1ALI A;  1E2S P;  3WAY A;  4CXU A;  1O99 A;  2XRG A;  4ZG7 A;  2GSO A;  1KHL A;  3M8Y A;  3WAX A;  1EQJ A;  1FSU A;  5INH A;  1KH4 A;  5GOV A;  3T02 A;  2XR9 A;  1EW2 A;  4LRD A;  5LIA A;  2GA3 A;  4GTY A;  3B5Q A;  3T01 A;  1P49 A;  5LRM A;  3BDF A;  4FDI A;  5KXA A;  4KM4 A;  1ALJ A;  3UN2 A;  1AJB A;  1ANJ A;  4CYR A;  4UOP A;  3T00 A;  2GLQ A;  2W5R A;  3M8Z A;  1E3C P;  4TN0 A;  2GSN A;  3KD8 A;  4UPH A;  1ELX A;  4YR1 A;  4CYS A;  4LQY A;  3MK1 A;  4KAY A;  5EGH A;  2IUC B;  5L0E A;  2D1G A;  3ED4 A;  5L0K A;  1E1Z P;  3IDD A;  2G9Y A;  5C66 A;  3MK2 A;  3Q3Q A;  5L0B A;  1AUK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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