1SHNA

Crystal structure of shrimp alkaline phosphatase with phosphate bound
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords alkaline phosphatase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shnA00
1E1ZP 1N2LA 1ZEFA 4B56A 1O99A 4KAVA 4CYRA 3UN3A 1ED8A 3KD8A 3T02A 2W8SA 5LRNA 5LRMA 4LR8A 1AJBA 3NKMA 4LRAA 5HRTA 3DYCA 1ZEDA 3CMRA 3BDGB 2GSUA 5AJ9A 4LRCA 3MK1A 4UPHA 4ZGAA 1KH4A 3ED4A 5DLWA 3BDFA 1E33P 2W5RA 3WAYA 4ZG6A 1KH5A 5INHA 2X98A 2GLQA 3M8YA 3Q3QA 5IJSA 3WAVA 3WAWA 3M8WA 1KHNA 3DPCA 2GSOA 1FSUA 2RH6A 1P49A 2D1GA 2XR9A 3NVLA 1KHLA 4KJGA 4CXUA 1N2KA 3UN2A 1ELZA 5L0BA 4TN0A 2W8DA 1ZEBA 4MHXA 1ALIA 1KH7A 3NKOA 1HDHA 3M7VA 4GTWA 3WAXA 4UPLA 4LRFA 4ZG9A 4LQYA 3UN5A 1E2SP 5KXAA 2IFYA 4CXSA 4KJDA 4LREA 5DLTA 4CYSA 3NKQA 5L0KA 4UPIA 3UNYA 1EW2A 2ZKTA 1HJKA 4LR7A 1ALHA 2ANHA 3NKNA 1ELYA 2IUCA 2W5TA 3NKPA 5EGEA 3SZYA 1SHNA 3NKRA 4UORA 2G9YA 1KHJA 1ANIA 1K7HA 1ALJA 1EQJA 4LRDA 5GRRA 4ZG7A 3BDHA 1ED9A 1Y7AA 5LQQA 1ANJA 4N7TA 2W5WA 4UOPA 1EW9A 3T01A 1KHKA 1SHQA 1KH9A 2IUCB 2XRGA 5TJ3A 5LIAA 2GSNA 3MK0A 4YR1A 4NWJA 3TX0A 3E2DA 3TG0A 1AUKA 5C66A 4KM4A 2GA3A 2W5SA 1AJAA 1B8JA 1AJDA 2W5VA 4MIVA 1ALKA 4UOOA 1URAA 1E3CP 3T00A 3IDDA 3IGYB 4LR2A 5GOVA 4FDJA 2QZUA 5IJQA 3TWZA 5DLVA 1EW8A 3SZZA 3IGZB 1URBA 4LR9A 3WBHA 4LRBA 5EGHA 1EJJA 3MK2A 4MY4A 4CXKA 1ELXA 5L0EA 4QAXA 1O98A 1HQAA 4FDIA 2W5QA 4KAYA 5K4PA 3UO0A 4UPKA 1AJCA 1Y6VA 3OT9A 1EI6A 2W5XA 3B5QA 4GTXA 4GTYA 3LXQA 4NWXA 2VQRA 3M8ZA 3BDGA 3A52A 4GTZA
chains in the Genus database with same CATH superfamily
1E1ZP 1N2LA 1ZEFA 4B56A 1O99A 4KAVA 4CYRA 3UN3A 1ED8A 3KD8A 3T02A 2W8SA 5LRNA 5LRMA 4LR8A 1AJBA 3NKMA 4LRAA 5HRTA 3DYCA 1ZEDA 3CMRA 3BDGB 2GSUA 5AJ9A 4LRCA 3MK1A 4UPHA 4ZGAA 1KH4A 3ED4A 5DLWA 3BDFA 1E33P 2W5RA 3WAYA 4ZG6A 1KH5A 5INHA 2X98A 2GLQA 3M8YA 3Q3QA 5IJSA 3WAVA 3WAWA 3M8WA 1KHNA 3DPCA 2GSOA 1FSUA 2RH6A 1P49A 2D1GA 2XR9A 3NVLA 1KHLA 4KJGA 4CXUA 1N2KA 3UN2A 1ELZA 5L0BA 4TN0A 2W8DA 1ZEBA 4MHXA 1ALIA 1KH7A 3NKOA 1HDHA 3M7VA 4GTWA 3WAXA 4UPLA 4LRFA 4ZG9A 4LQYA 3UN5A 1E2SP 5KXAA 2IFYA 4CXSA 4KJDA 4LREA 5DLTA 4CYSA 3NKQA 5L0KA 4UPIA 3UNYA 1EW2A 2ZKTA 1HJKA 4LR7A 1ALHA 2ANHA 3NKNA 1ELYA 2IUCA 2W5TA 3NKPA 5EGEA 3SZYA 1SHNA 3NKRA 4UORA 2G9YA 1KHJA 1ANIA 1K7HA 1ALJA 1EQJA 4LRDA 5GRRA 4ZG7A 3BDHA 1ED9A 1Y7AA 5LQQA 1ANJA 4N7TA 2W5WA 4UOPA 1EW9A 3T01A 1KHKA 1SHQA 1KH9A 2IUCB 2XRGA 5TJ3A 5LIAA 2GSNA 3MK0A 4YR1A 4NWJA 3TX0A 3E2DA 3TG0A 1AUKA 5C66A 4KM4A 2GA3A 2W5SA 1AJAA 1B8JA 1AJDA 2W5VA 4MIVA 1ALKA 4UOOA 1URAA 1E3CP 3T00A 3IDDA 3IGYB 4LR2A 5GOVA 4FDJA 2QZUA 5IJQA 3TWZA 5DLVA 1EW8A 3SZZA 3IGZB 1URBA 4LR9A 3WBHA 4LRBA 5EGHA 1EJJA 3MK2A 4MY4A 4CXKA 1ELXA 5L0EA 4QAXA 1O98A 1HQAA 4FDIA 2W5QA 4KAYA 5K4PA 3UO0A 4UPKA 1AJCA 1Y6VA 3OT9A 1EI6A 2W5XA 3B5QA 4GTXA 4GTYA 3LXQA 4NWXA 2VQRA 3M8ZA 3BDGA 3A52A 4GTZA
chains in the Genus database with same CATH topology
1E1ZP 1N2LA 1ZEFA 4B56A 1O99A 4KAVA 4CYRA 3UN3A 1ED8A 3KD8A 3T02A 2W8SA 5LRNA 5LRMA 4LR8A 1AJBA 3NKMA 4LRAA 5HRTA 3DYCA 1ZEDA 3CMRA 3BDGB 2GSUA 5AJ9A 4LRCA 3MK1A 4UPHA 4ZGAA 1KH4A 3ED4A 5DLWA 3BDFA 1E33P 2W5RA 3WAYA 4ZG6A 1KH5A 5INHA 2X98A 2GLQA 3M8YA 3Q3QA 5IJSA 3WAVA 3WAWA 3M8WA 1KHNA 3DPCA 2GSOA 1FSUA 2RH6A 1P49A 2D1GA 2XR9A 3NVLA 1KHLA 4KJGA 4CXUA 1N2KA 3UN2A 1ELZA 5L0BA 4TN0A 2W8DA 1ZEBA 4MHXA 1ALIA 1KH7A 3NKOA 1HDHA 3M7VA 4GTWA 3WAXA 4UPLA 4LRFA 4ZG9A 4LQYA 3UN5A 1E2SP 5KXAA 2IFYA 4CXSA 4KJDA 4LREA 5DLTA 4CYSA 3NKQA 5L0KA 4UPIA 3UNYA 1EW2A 2ZKTA 1HJKA 4LR7A 1ALHA 2ANHA 3NKNA 1ELYA 2IUCA 2W5TA 3NKPA 5EGEA 3SZYA 1SHNA 3NKRA 4UORA 2G9YA 1KHJA 1ANIA 1K7HA 1ALJA 1EQJA 4LRDA 5GRRA 4ZG7A 3BDHA 1ED9A 1Y7AA 5LQQA 1ANJA 4N7TA 2W5WA 4UOPA 1EW9A 3T01A 1KHKA 1SHQA 1KH9A 2IUCB 2XRGA 5TJ3A 5LIAA 2GSNA 3MK0A 4YR1A 4NWJA 3TX0A 3E2DA 3TG0A 1AUKA 5C66A 4KM4A 2GA3A 2W5SA 1AJAA 1B8JA 1AJDA 2W5VA 4MIVA 1ALKA 4UOOA 1URAA 1E3CP 3T00A 3IDDA 3IGYB 4LR2A 5GOVA 4FDJA 2QZUA 5IJQA 3TWZA 5DLVA 1EW8A 3SZZA 3IGZB 1URBA 4LR9A 3WBHA 4LRBA 5EGHA 1EJJA 3MK2A 4MY4A 4CXKA 1ELXA 5L0EA 4QAXA 1O98A 1HQAA 4FDIA 2W5QA 4KAYA 5K4PA 3UO0A 4UPKA 1AJCA 1Y6VA 3OT9A 1EI6A 2W5XA 3B5QA 4GTXA 4GTYA 3LXQA 4NWXA 2VQRA 3M8ZA 3BDGA 3A52A 4GTZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E1Z P;  1N2L A;  1ZEF A;  4B56 A;  1O99 A;  4KAV A;  4CYR A;  3UN3 A;  1ED8 A;  3KD8 A;  3T02 A;  2W8S A;  5LRN A;  5LRM A;  4LR8 A;  1AJB A;  3NKM A;  4LRA A;  5HRT A;  3DYC A;  1ZED A;  3CMR A;  3BDG B;  2GSU A;  5AJ9 A;  4LRC A;  3MK1 A;  4UPH A;  4ZGA A;  1KH4 A;  3ED4 A;  5DLW A;  3BDF A;  1E33 P;  2W5R A;  3WAY A;  4ZG6 A;  1KH5 A;  5INH A;  2X98 A;  2GLQ A;  3M8Y A;  3Q3Q A;  5IJS A;  3WAV A;  3WAW A;  3M8W A;  1KHN A;  3DPC A;  2GSO A;  1FSU A;  2RH6 A;  1P49 A;  2D1G A;  2XR9 A;  3NVL A;  1KHL A;  4KJG A;  4CXU A;  1N2K A;  3UN2 A;  1ELZ A;  5L0B A;  4TN0 A;  2W8D A;  1ZEB A;  4MHX A;  1ALI A;  1KH7 A;  3NKO A;  1HDH A;  3M7V A;  4GTW A;  3WAX A;  4UPL A;  4LRF A;  4ZG9 A;  4LQY A;  3UN5 A;  1E2S P;  5KXA A;  2IFY A;  4CXS A;  4KJD A;  4LRE A;  5DLT A;  4CYS A;  3NKQ A;  5L0K A;  4UPI A;  3UNY A;  1EW2 A;  2ZKT A;  1HJK A;  4LR7 A;  1ALH A;  2ANH A;  3NKN A;  1ELY A;  2IUC A;  2W5T A;  3NKP A;  5EGE A;  3SZY A;  1SHN A;  3NKR A;  4UOR A;  2G9Y A;  1KHJ A;  1ANI A;  1K7H A;  1ALJ A;  1EQJ A;  4LRD A;  5GRR A;  4ZG7 A;  3BDH A;  1ED9 A;  1Y7A A;  5LQQ A;  1ANJ A;  4N7T A;  2W5W A;  4UOP A;  1EW9 A;  3T01 A;  1KHK A;  1SHQ A;  1KH9 A;  2IUC B;  2XRG A;  5TJ3 A;  5LIA A;  2GSN A;  3MK0 A;  4YR1 A;  4NWJ A;  3TX0 A;  3E2D A;  3TG0 A;  1AUK A;  5C66 A;  4KM4 A;  2GA3 A;  2W5S A;  1AJA A;  1B8J A;  1AJD A;  2W5V A;  4MIV A;  1ALK A;  4UOO A;  1URA A;  1E3C P;  3T00 A;  3IDD A;  3IGY B;  4LR2 A;  5GOV A;  4FDJ A;  2QZU A;  5IJQ A;  3TWZ A;  5DLV A;  1EW8 A;  3SZZ A;  3IGZ B;  1URB A;  4LR9 A;  3WBH A;  4LRB A;  5EGH A;  1EJJ A;  3MK2 A;  4MY4 A;  4CXK A;  1ELX A;  5L0E A;  4QAX A;  1O98 A;  1HQA A;  4FDI A;  2W5Q A;  4KAY A;  5K4P A;  3UO0 A;  4UPK A;  1AJC A;  1Y6V A;  3OT9 A;  1EI6 A;  2W5X A;  3B5Q A;  4GTX A;  4GTY A;  3LXQ A;  4NWX A;  2VQR A;  3M8Z A;  3BDG A;  3A52 A;  4GTZ A; 
#chains in the Genus database with same CATH topology
 1E1Z P;  1N2L A;  1ZEF A;  4B56 A;  1O99 A;  4KAV A;  4CYR A;  3UN3 A;  1ED8 A;  3KD8 A;  3T02 A;  2W8S A;  5LRN A;  5LRM A;  4LR8 A;  1AJB A;  3NKM A;  4LRA A;  5HRT A;  3DYC A;  1ZED A;  3CMR A;  3BDG B;  2GSU A;  5AJ9 A;  4LRC A;  3MK1 A;  4UPH A;  4ZGA A;  1KH4 A;  3ED4 A;  5DLW A;  3BDF A;  1E33 P;  2W5R A;  3WAY A;  4ZG6 A;  1KH5 A;  5INH A;  2X98 A;  2GLQ A;  3M8Y A;  3Q3Q A;  5IJS A;  3WAV A;  3WAW A;  3M8W A;  1KHN A;  3DPC A;  2GSO A;  1FSU A;  2RH6 A;  1P49 A;  2D1G A;  2XR9 A;  3NVL A;  1KHL A;  4KJG A;  4CXU A;  1N2K A;  3UN2 A;  1ELZ A;  5L0B A;  4TN0 A;  2W8D A;  1ZEB A;  4MHX A;  1ALI A;  1KH7 A;  3NKO A;  1HDH A;  3M7V A;  4GTW A;  3WAX A;  4UPL A;  4LRF A;  4ZG9 A;  4LQY A;  3UN5 A;  1E2S P;  5KXA A;  2IFY A;  4CXS A;  4KJD A;  4LRE A;  5DLT A;  4CYS A;  3NKQ A;  5L0K A;  4UPI A;  3UNY A;  1EW2 A;  2ZKT A;  1HJK A;  4LR7 A;  1ALH A;  2ANH A;  3NKN A;  1ELY A;  2IUC A;  2W5T A;  3NKP A;  5EGE A;  3SZY A;  1SHN A;  3NKR A;  4UOR A;  2G9Y A;  1KHJ A;  1ANI A;  1K7H A;  1ALJ A;  1EQJ A;  4LRD A;  5GRR A;  4ZG7 A;  3BDH A;  1ED9 A;  1Y7A A;  5LQQ A;  1ANJ A;  4N7T A;  2W5W A;  4UOP A;  1EW9 A;  3T01 A;  1KHK A;  1SHQ A;  1KH9 A;  2IUC B;  2XRG A;  5TJ3 A;  5LIA A;  2GSN A;  3MK0 A;  4YR1 A;  4NWJ A;  3TX0 A;  3E2D A;  3TG0 A;  1AUK A;  5C66 A;  4KM4 A;  2GA3 A;  2W5S A;  1AJA A;  1B8J A;  1AJD A;  2W5V A;  4MIV A;  1ALK A;  4UOO A;  1URA A;  1E3C P;  3T00 A;  3IDD A;  3IGY B;  4LR2 A;  5GOV A;  4FDJ A;  2QZU A;  5IJQ A;  3TWZ A;  5DLV A;  1EW8 A;  3SZZ A;  3IGZ B;  1URB A;  4LR9 A;  3WBH A;  4LRB A;  5EGH A;  1EJJ A;  3MK2 A;  4MY4 A;  4CXK A;  1ELX A;  5L0E A;  4QAX A;  1O98 A;  1HQA A;  4FDI A;  2W5Q A;  4KAY A;  5K4P A;  3UO0 A;  4UPK A;  1AJC A;  1Y6V A;  3OT9 A;  1EI6 A;  2W5X A;  3B5Q A;  4GTX A;  4GTY A;  3LXQ A;  4NWX A;  2VQR A;  3M8Z A;  3BDG A;  3A52 A;  4GTZ A; 
#chains in the Genus database with same CATH homology
 1E1Z P;  1N2L A;  1ZEF A;  4B56 A;  1O99 A;  4KAV A;  4CYR A;  3UN3 A;  1ED8 A;  3KD8 A;  3T02 A;  2W8S A;  5LRN A;  5LRM A;  4LR8 A;  1AJB A;  3NKM A;  4LRA A;  5HRT A;  3DYC A;  1ZED A;  3CMR A;  3BDG B;  2GSU A;  5AJ9 A;  4LRC A;  3MK1 A;  4UPH A;  4ZGA A;  1KH4 A;  3ED4 A;  5DLW A;  3BDF A;  1E33 P;  2W5R A;  3WAY A;  4ZG6 A;  1KH5 A;  5INH A;  2X98 A;  2GLQ A;  3M8Y A;  3Q3Q A;  5IJS A;  3WAV A;  3WAW A;  3M8W A;  1KHN A;  3DPC A;  2GSO A;  1FSU A;  2RH6 A;  1P49 A;  2D1G A;  2XR9 A;  3NVL A;  1KHL A;  4KJG A;  4CXU A;  1N2K A;  3UN2 A;  1ELZ A;  5L0B A;  4TN0 A;  2W8D A;  1ZEB A;  4MHX A;  1ALI A;  1KH7 A;  3NKO A;  1HDH A;  3M7V A;  4GTW A;  3WAX A;  4UPL A;  4LRF A;  4ZG9 A;  4LQY A;  3UN5 A;  1E2S P;  5KXA A;  2IFY A;  4CXS A;  4KJD A;  4LRE A;  5DLT A;  4CYS A;  3NKQ A;  5L0K A;  4UPI A;  3UNY A;  1EW2 A;  2ZKT A;  1HJK A;  4LR7 A;  1ALH A;  2ANH A;  3NKN A;  1ELY A;  2IUC A;  2W5T A;  3NKP A;  5EGE A;  3SZY A;  1SHN A;  3NKR A;  4UOR A;  2G9Y A;  1KHJ A;  1ANI A;  1K7H A;  1ALJ A;  1EQJ A;  4LRD A;  5GRR A;  4ZG7 A;  3BDH A;  1ED9 A;  1Y7A A;  5LQQ A;  1ANJ A;  4N7T A;  2W5W A;  4UOP A;  1EW9 A;  3T01 A;  1KHK A;  1SHQ A;  1KH9 A;  2IUC B;  2XRG A;  5TJ3 A;  5LIA A;  2GSN A;  3MK0 A;  4YR1 A;  4NWJ A;  3TX0 A;  3E2D A;  3TG0 A;  1AUK A;  5C66 A;  4KM4 A;  2GA3 A;  2W5S A;  1AJA A;  1B8J A;  1AJD A;  2W5V A;  4MIV A;  1ALK A;  4UOO A;  1URA A;  1E3C P;  3T00 A;  3IDD A;  3IGY B;  4LR2 A;  5GOV A;  4FDJ A;  2QZU A;  5IJQ A;  3TWZ A;  5DLV A;  1EW8 A;  3SZZ A;  3IGZ B;  1URB A;  4LR9 A;  3WBH A;  4LRB A;  5EGH A;  1EJJ A;  3MK2 A;  4MY4 A;  4CXK A;  1ELX A;  5L0E A;  4QAX A;  1O98 A;  1HQA A;  4FDI A;  2W5Q A;  4KAY A;  5K4P A;  3UO0 A;  4UPK A;  1AJC A;  1Y6V A;  3OT9 A;  1EI6 A;  2W5X A;  3B5Q A;  4GTX A;  4GTY A;  3LXQ A;  4NWX A;  2VQR A;  3M8Z A;  3BDG A;  3A52 A;  4GTZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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