1ELZA

E. coli alkaline phosphatase mutant (s102g)
Total Genus 157
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
157
Knots found
sequence length
449
structure length
449
Chain Sequence
b'TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDGAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords ALKALINE PHOSPHATASE
publication title Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 157
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1998-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1elzA00
1AJCA 1URBA 1EW9A 1E1ZP 1ZEFA 1KHNA 2XRGA 1ELZA 4LR2A 1ELYA 4LQYA 1EJJA 2W5VA 3M8YA 4LRFA 2VQRA 2RH6A 3SZZA 3TX0A 4LRBA 5EGEA 3BDGB 4FDIA 3T00A 1KHLA 1ED8A 3UO0A 5DLWA 1KH4A 3UN2A 5LRMA 5TJ3A 3A52A 3NKQA 2W5SA 4QAXA 1KHKA 2W5RA 3MK2A 4CYRA 3DYCA 5L0EA 1ZEDA 4CXKA 1KHJA 5AJ9A 3E2DA 3NVLA 3T01A 1ALJA 3KD8A 3MK0A 4GTWA 4KAVA 4ZG6A 4YR1A 1ALKA 2GLQA 4LRCA 3NKMA 1AJBA 1ED9A 3T02A 1K7HA 3NKOA 5LQQA 3TWZA 1E33P 1EW2A 2QZUA 3BDHA 4GTZA 4KM4A 4ZG7A 3CMRA 5HRTA 3M8ZA 3WAVA 1AJAA 2G9YA 5DLVA 1KH7A 3WAYA 1ALHA 3WAXA 4UOOA 4LRAA 2GSNA 4CXSA 1EW8A 1ALIA 1HQAA 4ZGAA 5GRRA 4FDJA 2ANHA 3SZYA 1SHQA 1ZEBA 1FSUA 4CYSA 2W8DA 3BDGA 5IJQA 3ED4A 1N2KA 1Y7AA 1E3CP 4LREA 4UORA 3BDFA 1ANJA 3WBHA 1KH5A 3IGZB 3M8WA 4N7TA 1SHNA 4LR7A 3NKNA 4GTYA 1URAA 1HDHA 4LR9A 1KH9A 4LR8A 4MIVA 1O98A 1Y6VA 4GTXA 4TN0A 1E2SP 5IJSA 5L0BA 4UPIA 5LIAA 3MK1A 2IFYA 4NWJA 3UN3A 4UOPA 5EGHA 4KJDA 2GSUA 3NKPA 4KAYA 3LXQA 5GOVA 4UPKA 4B56A 4CXUA 2W5WA 3DPCA 5KXAA 5L0KA 1P49A 5DLTA 3WAWA 4KJGA 2IUCB 2W5QA 2W8SA 5LRNA 3NKRA 1AJDA 3B5QA 3M7VA 1HJKA 2XR9A 4NWXA 1B8JA 1EQJA 1N2LA 5K4PA 2ZKTA 2GSOA 5INHA 4LRDA 4MHXA 2GA3A 1AUKA 2X98A 4MY4A 2IUCA 3UNYA 3IDDA 3IGYB 3Q3QA 1ELXA 1O99A 2D1GA 4UPHA 4UPLA 3OT9A 3UN5A 2W5TA 5C66A 4ZG9A 1ANIA 3TG0A 2W5XA 1EI6A
chains in the Genus database with same CATH superfamily
1AJCA 1URBA 1EW9A 1E1ZP 1ZEFA 1KHNA 2XRGA 1ELZA 4LR2A 1ELYA 4LQYA 1EJJA 2W5VA 3M8YA 4LRFA 2VQRA 2RH6A 3SZZA 3TX0A 4LRBA 5EGEA 3BDGB 4FDIA 3T00A 1KHLA 1ED8A 3UO0A 5DLWA 1KH4A 3UN2A 5LRMA 5TJ3A 3A52A 3NKQA 2W5SA 4QAXA 1KHKA 2W5RA 3MK2A 4CYRA 3DYCA 5L0EA 1ZEDA 4CXKA 1KHJA 5AJ9A 3E2DA 3NVLA 3T01A 1ALJA 3KD8A 3MK0A 4GTWA 4KAVA 4ZG6A 4YR1A 1ALKA 2GLQA 4LRCA 3NKMA 1AJBA 1ED9A 3T02A 1K7HA 3NKOA 5LQQA 3TWZA 1E33P 1EW2A 2QZUA 3BDHA 4GTZA 4KM4A 4ZG7A 3CMRA 5HRTA 3M8ZA 3WAVA 1AJAA 2G9YA 5DLVA 1KH7A 3WAYA 1ALHA 3WAXA 4UOOA 4LRAA 2GSNA 4CXSA 1EW8A 1ALIA 1HQAA 4ZGAA 5GRRA 4FDJA 2ANHA 3SZYA 1SHQA 1ZEBA 1FSUA 4CYSA 2W8DA 3BDGA 5IJQA 3ED4A 1N2KA 1Y7AA 1E3CP 4LREA 4UORA 3BDFA 1ANJA 3WBHA 1KH5A 3IGZB 3M8WA 4N7TA 1SHNA 4LR7A 3NKNA 4GTYA 1URAA 1HDHA 4LR9A 1KH9A 4LR8A 4MIVA 1O98A 1Y6VA 4GTXA 4TN0A 1E2SP 5IJSA 5L0BA 4UPIA 5LIAA 3MK1A 2IFYA 4NWJA 3UN3A 4UOPA 5EGHA 4KJDA 2GSUA 3NKPA 4KAYA 3LXQA 5GOVA 4UPKA 4B56A 4CXUA 2W5WA 3DPCA 5KXAA 5L0KA 1P49A 5DLTA 3WAWA 4KJGA 2IUCB 2W5QA 2W8SA 5LRNA 3NKRA 1AJDA 3B5QA 3M7VA 1HJKA 2XR9A 4NWXA 1B8JA 1EQJA 1N2LA 5K4PA 2ZKTA 2GSOA 5INHA 4LRDA 4MHXA 2GA3A 1AUKA 2X98A 4MY4A 2IUCA 3UNYA 3IDDA 3IGYB 3Q3QA 1ELXA 1O99A 2D1GA 4UPHA 4UPLA 3OT9A 3UN5A 2W5TA 5C66A 4ZG9A 1ANIA 3TG0A 2W5XA 1EI6A
chains in the Genus database with same CATH topology
1AJCA 1URBA 1EW9A 1E1ZP 1ZEFA 1KHNA 2XRGA 1ELZA 4LR2A 1ELYA 4LQYA 1EJJA 2W5VA 3M8YA 4LRFA 2VQRA 2RH6A 3SZZA 3TX0A 4LRBA 5EGEA 3BDGB 4FDIA 3T00A 1KHLA 1ED8A 3UO0A 5DLWA 1KH4A 3UN2A 5LRMA 5TJ3A 3A52A 3NKQA 2W5SA 4QAXA 1KHKA 2W5RA 3MK2A 4CYRA 3DYCA 5L0EA 1ZEDA 4CXKA 1KHJA 5AJ9A 3E2DA 3NVLA 3T01A 1ALJA 3KD8A 3MK0A 4GTWA 4KAVA 4ZG6A 4YR1A 1ALKA 2GLQA 4LRCA 3NKMA 1AJBA 1ED9A 3T02A 1K7HA 3NKOA 5LQQA 3TWZA 1E33P 1EW2A 2QZUA 3BDHA 4GTZA 4KM4A 4ZG7A 3CMRA 5HRTA 3M8ZA 3WAVA 1AJAA 2G9YA 5DLVA 1KH7A 3WAYA 1ALHA 3WAXA 4UOOA 4LRAA 2GSNA 4CXSA 1EW8A 1ALIA 1HQAA 4ZGAA 5GRRA 4FDJA 2ANHA 3SZYA 1SHQA 1ZEBA 1FSUA 4CYSA 2W8DA 3BDGA 5IJQA 3ED4A 1N2KA 1Y7AA 1E3CP 4LREA 4UORA 3BDFA 1ANJA 3WBHA 1KH5A 3IGZB 3M8WA 4N7TA 1SHNA 4LR7A 3NKNA 4GTYA 1URAA 1HDHA 4LR9A 1KH9A 4LR8A 4MIVA 1O98A 1Y6VA 4GTXA 4TN0A 1E2SP 5IJSA 5L0BA 4UPIA 5LIAA 3MK1A 2IFYA 4NWJA 3UN3A 4UOPA 5EGHA 4KJDA 2GSUA 3NKPA 4KAYA 3LXQA 5GOVA 4UPKA 4B56A 4CXUA 2W5WA 3DPCA 5KXAA 5L0KA 1P49A 5DLTA 3WAWA 4KJGA 2IUCB 2W5QA 2W8SA 5LRNA 3NKRA 1AJDA 3B5QA 3M7VA 1HJKA 2XR9A 4NWXA 1B8JA 1EQJA 1N2LA 5K4PA 2ZKTA 2GSOA 5INHA 4LRDA 4MHXA 2GA3A 1AUKA 2X98A 4MY4A 2IUCA 3UNYA 3IDDA 3IGYB 3Q3QA 1ELXA 1O99A 2D1GA 4UPHA 4UPLA 3OT9A 3UN5A 2W5TA 5C66A 4ZG9A 1ANIA 3TG0A 2W5XA 1EI6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AJC A;  1URB A;  1EW9 A;  1E1Z P;  1ZEF A;  1KHN A;  2XRG A;  1ELZ A;  4LR2 A;  1ELY A;  4LQY A;  1EJJ A;  2W5V A;  3M8Y A;  4LRF A;  2VQR A;  2RH6 A;  3SZZ A;  3TX0 A;  4LRB A;  5EGE A;  3BDG B;  4FDI A;  3T00 A;  1KHL A;  1ED8 A;  3UO0 A;  5DLW A;  1KH4 A;  3UN2 A;  5LRM A;  5TJ3 A;  3A52 A;  3NKQ A;  2W5S A;  4QAX A;  1KHK A;  2W5R A;  3MK2 A;  4CYR A;  3DYC A;  5L0E A;  1ZED A;  4CXK A;  1KHJ A;  5AJ9 A;  3E2D A;  3NVL A;  3T01 A;  1ALJ A;  3KD8 A;  3MK0 A;  4GTW A;  4KAV A;  4ZG6 A;  4YR1 A;  1ALK A;  2GLQ A;  4LRC A;  3NKM A;  1AJB A;  1ED9 A;  3T02 A;  1K7H A;  3NKO A;  5LQQ A;  3TWZ A;  1E33 P;  1EW2 A;  2QZU A;  3BDH A;  4GTZ A;  4KM4 A;  4ZG7 A;  3CMR A;  5HRT A;  3M8Z A;  3WAV A;  1AJA A;  2G9Y A;  5DLV A;  1KH7 A;  3WAY A;  1ALH A;  3WAX A;  4UOO A;  4LRA A;  2GSN A;  4CXS A;  1EW8 A;  1ALI A;  1HQA A;  4ZGA A;  5GRR A;  4FDJ A;  2ANH A;  3SZY A;  1SHQ A;  1ZEB A;  1FSU A;  4CYS A;  2W8D A;  3BDG A;  5IJQ A;  3ED4 A;  1N2K A;  1Y7A A;  1E3C P;  4LRE A;  4UOR A;  3BDF A;  1ANJ A;  3WBH A;  1KH5 A;  3IGZ B;  3M8W A;  4N7T A;  1SHN A;  4LR7 A;  3NKN A;  4GTY A;  1URA A;  1HDH A;  4LR9 A;  1KH9 A;  4LR8 A;  4MIV A;  1O98 A;  1Y6V A;  4GTX A;  4TN0 A;  1E2S P;  5IJS A;  5L0B A;  4UPI A;  5LIA A;  3MK1 A;  2IFY A;  4NWJ A;  3UN3 A;  4UOP A;  5EGH A;  4KJD A;  2GSU A;  3NKP A;  4KAY A;  3LXQ A;  5GOV A;  4UPK A;  4B56 A;  4CXU A;  2W5W A;  3DPC A;  5KXA A;  5L0K A;  1P49 A;  5DLT A;  3WAW A;  4KJG A;  2IUC B;  2W5Q A;  2W8S A;  5LRN A;  3NKR A;  1AJD A;  3B5Q A;  3M7V A;  1HJK A;  2XR9 A;  4NWX A;  1B8J A;  1EQJ A;  1N2L A;  5K4P A;  2ZKT A;  2GSO A;  5INH A;  4LRD A;  4MHX A;  2GA3 A;  1AUK A;  2X98 A;  4MY4 A;  2IUC A;  3UNY A;  3IDD A;  3IGY B;  3Q3Q A;  1ELX A;  1O99 A;  2D1G A;  4UPH A;  4UPL A;  3OT9 A;  3UN5 A;  2W5T A;  5C66 A;  4ZG9 A;  1ANI A;  3TG0 A;  2W5X A;  1EI6 A; 
#chains in the Genus database with same CATH topology
 1AJC A;  1URB A;  1EW9 A;  1E1Z P;  1ZEF A;  1KHN A;  2XRG A;  1ELZ A;  4LR2 A;  1ELY A;  4LQY A;  1EJJ A;  2W5V A;  3M8Y A;  4LRF A;  2VQR A;  2RH6 A;  3SZZ A;  3TX0 A;  4LRB A;  5EGE A;  3BDG B;  4FDI A;  3T00 A;  1KHL A;  1ED8 A;  3UO0 A;  5DLW A;  1KH4 A;  3UN2 A;  5LRM A;  5TJ3 A;  3A52 A;  3NKQ A;  2W5S A;  4QAX A;  1KHK A;  2W5R A;  3MK2 A;  4CYR A;  3DYC A;  5L0E A;  1ZED A;  4CXK A;  1KHJ A;  5AJ9 A;  3E2D A;  3NVL A;  3T01 A;  1ALJ A;  3KD8 A;  3MK0 A;  4GTW A;  4KAV A;  4ZG6 A;  4YR1 A;  1ALK A;  2GLQ A;  4LRC A;  3NKM A;  1AJB A;  1ED9 A;  3T02 A;  1K7H A;  3NKO A;  5LQQ A;  3TWZ A;  1E33 P;  1EW2 A;  2QZU A;  3BDH A;  4GTZ A;  4KM4 A;  4ZG7 A;  3CMR A;  5HRT A;  3M8Z A;  3WAV A;  1AJA A;  2G9Y A;  5DLV A;  1KH7 A;  3WAY A;  1ALH A;  3WAX A;  4UOO A;  4LRA A;  2GSN A;  4CXS A;  1EW8 A;  1ALI A;  1HQA A;  4ZGA A;  5GRR A;  4FDJ A;  2ANH A;  3SZY A;  1SHQ A;  1ZEB A;  1FSU A;  4CYS A;  2W8D A;  3BDG A;  5IJQ A;  3ED4 A;  1N2K A;  1Y7A A;  1E3C P;  4LRE A;  4UOR A;  3BDF A;  1ANJ A;  3WBH A;  1KH5 A;  3IGZ B;  3M8W A;  4N7T A;  1SHN A;  4LR7 A;  3NKN A;  4GTY A;  1URA A;  1HDH A;  4LR9 A;  1KH9 A;  4LR8 A;  4MIV A;  1O98 A;  1Y6V A;  4GTX A;  4TN0 A;  1E2S P;  5IJS A;  5L0B A;  4UPI A;  5LIA A;  3MK1 A;  2IFY A;  4NWJ A;  3UN3 A;  4UOP A;  5EGH A;  4KJD A;  2GSU A;  3NKP A;  4KAY A;  3LXQ A;  5GOV A;  4UPK A;  4B56 A;  4CXU A;  2W5W A;  3DPC A;  5KXA A;  5L0K A;  1P49 A;  5DLT A;  3WAW A;  4KJG A;  2IUC B;  2W5Q A;  2W8S A;  5LRN A;  3NKR A;  1AJD A;  3B5Q A;  3M7V A;  1HJK A;  2XR9 A;  4NWX A;  1B8J A;  1EQJ A;  1N2L A;  5K4P A;  2ZKT A;  2GSO A;  5INH A;  4LRD A;  4MHX A;  2GA3 A;  1AUK A;  2X98 A;  4MY4 A;  2IUC A;  3UNY A;  3IDD A;  3IGY B;  3Q3Q A;  1ELX A;  1O99 A;  2D1G A;  4UPH A;  4UPL A;  3OT9 A;  3UN5 A;  2W5T A;  5C66 A;  4ZG9 A;  1ANI A;  3TG0 A;  2W5X A;  1EI6 A; 
#chains in the Genus database with same CATH homology
 1AJC A;  1URB A;  1EW9 A;  1E1Z P;  1ZEF A;  1KHN A;  2XRG A;  1ELZ A;  4LR2 A;  1ELY A;  4LQY A;  1EJJ A;  2W5V A;  3M8Y A;  4LRF A;  2VQR A;  2RH6 A;  3SZZ A;  3TX0 A;  4LRB A;  5EGE A;  3BDG B;  4FDI A;  3T00 A;  1KHL A;  1ED8 A;  3UO0 A;  5DLW A;  1KH4 A;  3UN2 A;  5LRM A;  5TJ3 A;  3A52 A;  3NKQ A;  2W5S A;  4QAX A;  1KHK A;  2W5R A;  3MK2 A;  4CYR A;  3DYC A;  5L0E A;  1ZED A;  4CXK A;  1KHJ A;  5AJ9 A;  3E2D A;  3NVL A;  3T01 A;  1ALJ A;  3KD8 A;  3MK0 A;  4GTW A;  4KAV A;  4ZG6 A;  4YR1 A;  1ALK A;  2GLQ A;  4LRC A;  3NKM A;  1AJB A;  1ED9 A;  3T02 A;  1K7H A;  3NKO A;  5LQQ A;  3TWZ A;  1E33 P;  1EW2 A;  2QZU A;  3BDH A;  4GTZ A;  4KM4 A;  4ZG7 A;  3CMR A;  5HRT A;  3M8Z A;  3WAV A;  1AJA A;  2G9Y A;  5DLV A;  1KH7 A;  3WAY A;  1ALH A;  3WAX A;  4UOO A;  4LRA A;  2GSN A;  4CXS A;  1EW8 A;  1ALI A;  1HQA A;  4ZGA A;  5GRR A;  4FDJ A;  2ANH A;  3SZY A;  1SHQ A;  1ZEB A;  1FSU A;  4CYS A;  2W8D A;  3BDG A;  5IJQ A;  3ED4 A;  1N2K A;  1Y7A A;  1E3C P;  4LRE A;  4UOR A;  3BDF A;  1ANJ A;  3WBH A;  1KH5 A;  3IGZ B;  3M8W A;  4N7T A;  1SHN A;  4LR7 A;  3NKN A;  4GTY A;  1URA A;  1HDH A;  4LR9 A;  1KH9 A;  4LR8 A;  4MIV A;  1O98 A;  1Y6V A;  4GTX A;  4TN0 A;  1E2S P;  5IJS A;  5L0B A;  4UPI A;  5LIA A;  3MK1 A;  2IFY A;  4NWJ A;  3UN3 A;  4UOP A;  5EGH A;  4KJD A;  2GSU A;  3NKP A;  4KAY A;  3LXQ A;  5GOV A;  4UPK A;  4B56 A;  4CXU A;  2W5W A;  3DPC A;  5KXA A;  5L0K A;  1P49 A;  5DLT A;  3WAW A;  4KJG A;  2IUC B;  2W5Q A;  2W8S A;  5LRN A;  3NKR A;  1AJD A;  3B5Q A;  3M7V A;  1HJK A;  2XR9 A;  4NWX A;  1B8J A;  1EQJ A;  1N2L A;  5K4P A;  2ZKT A;  2GSO A;  5INH A;  4LRD A;  4MHX A;  2GA3 A;  1AUK A;  2X98 A;  4MY4 A;  2IUC A;  3UNY A;  3IDD A;  3IGY B;  3Q3Q A;  1ELX A;  1O99 A;  2D1G A;  4UPH A;  4UPL A;  3OT9 A;  3UN5 A;  2W5T A;  5C66 A;  4ZG9 A;  1ANI A;  3TG0 A;  2W5X A;  1EI6 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...