1SHNA

Crystal structure of shrimp alkaline phosphatase with phosphate bound
Total Genus 187
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
187
Knots found
sequence length
476
structure length
476
Chain Sequence
EEDKAYWNKDAQDALDKQLGIKLREKQAKNVIFFLGDGMSLSTVTAARIYKGGLTGKFEREKISWEEFDFAALSKTYNTDKQVTDSAASATAYLTGVKTNQGVIGLDANTVRTNCSYQLDESLFTYSIAHWFQEAGRSTGVVTSTRVTHATPAGTYAHVADRDWENDSDVVHDREDPEICDDIAEQLVFREPGKNFKVIMGGGRRGFFPEEALDIEDGIPGEREDGKHLITDWLDDKASQGATASYVWNRDDLLAVDIRNTDYLMGLFSYTHLDTVLTRDAEMDPTLPEMTKVAIEMLTKDENGFFLLVEGGRIDHMHHANQIRQSLAETLDMEEAVSMALSMTDPEETIILVTADHGHTLTITGYADRNTDILDFAGISDLDDRRYTILDYGSGPGYHITEDGKRYEPTEEDLKDINFRYASAAPKHSVTHDGTDVGIWVNGPFAHLFTGVYEENYIPHALAYAACVGTGRTFCD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords alkaline phosphatase
total genus 187
structure length 476
sequence length 476
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2004-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1shnA00
4UPKA 1ALIA 3B5QA 4ZG6A 2W5WA 3NKRA 2IUCB 4LRBA 4B56A 4CYSA 3UN3A 1O99A 5KXAA 4UPHA 5IJSA 4GTZA 4ZGAA 4CXSA 1AJBA 5LRMA 3DYCA 4N7TA 4MIVA 1FSUA 1KHKA 3ED4A 4KAYA 1EW9A 2GSUA 4GTYA 2GSNA 1HDHA 1E33P 5AJ9A 3SZZA 1ELZA 1AJCA 1KHLA 1KH9A 1EW8A 1N2KA 5L0BA 1HQAA 2W5QA 4GTWA 3NKNA 3KD8A 4LR2A 2IUCA 1EJJA 2D1GA 1URAA 1ED9A 4LR8A 3WAVA 3BDFA 3T01A 3M8YA 4FDIA 1AJAA 1EW2A 2RH6A 1ANIA 3NKOA 2VQRA 5EGEA 1AUKA 4KJGA 5L0KA 3WAXA 4UOPA 5EGHA 4UPLA 1SHNA 1ANJA 5DLWA 4FDJA 2ANHA 4LRDA 1ALKA 5LQQA 5GOVA 1EQJA 1P49A 3MK1A 2W5XA 3NKMA 1KHJA 1O98A 3UO0A 2ZKTA 5C66A 2W5SA 1KH5A 3NKQA 3T00A 5DLVA 3TX0A 1N2LA 1ZEDA 1B8JA 2GLQA 4NWXA 3Q3QA 3IGYB 1ZEFA 4LR7A 2W5RA 1KH7A 4LRCA 5LRNA 1Y6VA 3UN2A 1ELXA 5TJ3A 2XRGA 1ED8A 4QAXA 1Y7AA 3CMRA 1KHNA 3TG0A 4CXKA 3LXQA 1ALJA 1ELYA 1SHQA 1ZEBA 5HRTA 3BDHA 4KAVA 3WBHA 3OT9A 3TWZA 5INHA 3M8ZA 2W5VA 1EI6A 4CYRA 5IJQA 2W8SA 4KJDA 2QZUA 4KM4A 5GRRA 4ZG9A 2W5TA 3MK2A 1E2SP 3T02A 3E2DA 3WAWA 3NKPA 5K4PA 3A52A 3MK0A 4MY4A 3IDDA 3SZYA 1E1ZP 4UPIA 4LQYA 3BDGA 4UOOA 2GA3A 1E3CP 2XR9A 3NVLA 2IFYA 4LREA 3M7VA 4YR1A 3M8WA 4TN0A 2W8DA 3IGZB 1KH4A 4ZG7A 5LIAA 1AJDA 4MHXA 4GTXA 3BDGB 3DPCA 3UNYA 3WAYA 1ALHA 1K7HA 2G9YA 4LRFA 4LRAA 1HJKA 2X98A 3UN5A 4NWJA 5L0EA 5DLTA 2GSOA 4CXUA 4LR9A 1URBA 4UORA
chains in the Genus database with same CATH superfamily
4UPKA 1ALIA 3B5QA 4ZG6A 2W5WA 3NKRA 2IUCB 4LRBA 4B56A 4CYSA 3UN3A 1O99A 5KXAA 4UPHA 5IJSA 4GTZA 4ZGAA 4CXSA 1AJBA 5LRMA 3DYCA 4N7TA 4MIVA 1FSUA 1KHKA 3ED4A 4KAYA 1EW9A 2GSUA 4GTYA 2GSNA 1HDHA 1E33P 5AJ9A 3SZZA 1ELZA 1AJCA 1KHLA 1KH9A 1EW8A 1N2KA 5L0BA 1HQAA 2W5QA 4GTWA 3NKNA 3KD8A 4LR2A 2IUCA 1EJJA 2D1GA 1URAA 1ED9A 4LR8A 3WAVA 3BDFA 3T01A 3M8YA 4FDIA 1AJAA 1EW2A 2RH6A 1ANIA 3NKOA 2VQRA 5EGEA 1AUKA 4KJGA 5L0KA 3WAXA 4UOPA 5EGHA 4UPLA 1SHNA 1ANJA 5DLWA 4FDJA 2ANHA 4LRDA 1ALKA 5LQQA 5GOVA 1EQJA 1P49A 3MK1A 2W5XA 3NKMA 1KHJA 1O98A 3UO0A 2ZKTA 5C66A 2W5SA 1KH5A 3NKQA 3T00A 5DLVA 3TX0A 1N2LA 1ZEDA 1B8JA 2GLQA 4NWXA 3Q3QA 3IGYB 1ZEFA 4LR7A 2W5RA 1KH7A 4LRCA 5LRNA 1Y6VA 3UN2A 1ELXA 5TJ3A 2XRGA 1ED8A 4QAXA 1Y7AA 3CMRA 1KHNA 3TG0A 4CXKA 3LXQA 1ALJA 1ELYA 1SHQA 1ZEBA 5HRTA 3BDHA 4KAVA 3WBHA 3OT9A 3TWZA 5INHA 3M8ZA 2W5VA 1EI6A 4CYRA 5IJQA 2W8SA 4KJDA 2QZUA 4KM4A 5GRRA 4ZG9A 2W5TA 3MK2A 1E2SP 3T02A 3E2DA 3WAWA 3NKPA 5K4PA 3A52A 3MK0A 4MY4A 3IDDA 3SZYA 1E1ZP 4UPIA 4LQYA 3BDGA 4UOOA 2GA3A 1E3CP 2XR9A 3NVLA 2IFYA 4LREA 3M7VA 4YR1A 3M8WA 4TN0A 2W8DA 3IGZB 1KH4A 4ZG7A 5LIAA 1AJDA 4MHXA 4GTXA 3BDGB 3DPCA 3UNYA 3WAYA 1ALHA 1K7HA 2G9YA 4LRFA 4LRAA 1HJKA 2X98A 3UN5A 4NWJA 5L0EA 5DLTA 2GSOA 4CXUA 4LR9A 1URBA 4UORA
chains in the Genus database with same CATH topology
4UPKA 1ALIA 3B5QA 4ZG6A 2W5WA 3NKRA 2IUCB 4LRBA 4B56A 4CYSA 3UN3A 1O99A 5KXAA 4UPHA 5IJSA 4GTZA 4ZGAA 4CXSA 1AJBA 5LRMA 3DYCA 4N7TA 4MIVA 1FSUA 1KHKA 3ED4A 4KAYA 1EW9A 2GSUA 4GTYA 2GSNA 1HDHA 1E33P 5AJ9A 3SZZA 1ELZA 1AJCA 1KHLA 1KH9A 1EW8A 1N2KA 5L0BA 1HQAA 2W5QA 4GTWA 3NKNA 3KD8A 4LR2A 2IUCA 1EJJA 2D1GA 1URAA 1ED9A 4LR8A 3WAVA 3BDFA 3T01A 3M8YA 4FDIA 1AJAA 1EW2A 2RH6A 1ANIA 3NKOA 2VQRA 5EGEA 1AUKA 4KJGA 5L0KA 3WAXA 4UOPA 5EGHA 4UPLA 1SHNA 1ANJA 5DLWA 4FDJA 2ANHA 4LRDA 1ALKA 5LQQA 5GOVA 1EQJA 1P49A 3MK1A 2W5XA 3NKMA 1KHJA 1O98A 3UO0A 2ZKTA 5C66A 2W5SA 1KH5A 3NKQA 3T00A 5DLVA 3TX0A 1N2LA 1ZEDA 1B8JA 2GLQA 4NWXA 3Q3QA 3IGYB 1ZEFA 4LR7A 2W5RA 1KH7A 4LRCA 5LRNA 1Y6VA 3UN2A 1ELXA 5TJ3A 2XRGA 1ED8A 4QAXA 1Y7AA 3CMRA 1KHNA 3TG0A 4CXKA 3LXQA 1ALJA 1ELYA 1SHQA 1ZEBA 5HRTA 3BDHA 4KAVA 3WBHA 3OT9A 3TWZA 5INHA 3M8ZA 2W5VA 1EI6A 4CYRA 5IJQA 2W8SA 4KJDA 2QZUA 4KM4A 5GRRA 4ZG9A 2W5TA 3MK2A 1E2SP 3T02A 3E2DA 3WAWA 3NKPA 5K4PA 3A52A 3MK0A 4MY4A 3IDDA 3SZYA 1E1ZP 4UPIA 4LQYA 3BDGA 4UOOA 2GA3A 1E3CP 2XR9A 3NVLA 2IFYA 4LREA 3M7VA 4YR1A 3M8WA 4TN0A 2W8DA 3IGZB 1KH4A 4ZG7A 5LIAA 1AJDA 4MHXA 4GTXA 3BDGB 3DPCA 3UNYA 3WAYA 1ALHA 1K7HA 2G9YA 4LRFA 4LRAA 1HJKA 2X98A 3UN5A 4NWJA 5L0EA 5DLTA 2GSOA 4CXUA 4LR9A 1URBA 4UORA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UPK A;  1ALI A;  3B5Q A;  4ZG6 A;  2W5W A;  3NKR A;  2IUC B;  4LRB A;  4B56 A;  4CYS A;  3UN3 A;  1O99 A;  5KXA A;  4UPH A;  5IJS A;  4GTZ A;  4ZGA A;  4CXS A;  1AJB A;  5LRM A;  3DYC A;  4N7T A;  4MIV A;  1FSU A;  1KHK A;  3ED4 A;  4KAY A;  1EW9 A;  2GSU A;  4GTY A;  2GSN A;  1HDH A;  1E33 P;  5AJ9 A;  3SZZ A;  1ELZ A;  1AJC A;  1KHL A;  1KH9 A;  1EW8 A;  1N2K A;  5L0B A;  1HQA A;  2W5Q A;  4GTW A;  3NKN A;  3KD8 A;  4LR2 A;  2IUC A;  1EJJ A;  2D1G A;  1URA A;  1ED9 A;  4LR8 A;  3WAV A;  3BDF A;  3T01 A;  3M8Y A;  4FDI A;  1AJA A;  1EW2 A;  2RH6 A;  1ANI A;  3NKO A;  2VQR A;  5EGE A;  1AUK A;  4KJG A;  5L0K A;  3WAX A;  4UOP A;  5EGH A;  4UPL A;  1SHN A;  1ANJ A;  5DLW A;  4FDJ A;  2ANH A;  4LRD A;  1ALK A;  5LQQ A;  5GOV A;  1EQJ A;  1P49 A;  3MK1 A;  2W5X A;  3NKM A;  1KHJ A;  1O98 A;  3UO0 A;  2ZKT A;  5C66 A;  2W5S A;  1KH5 A;  3NKQ A;  3T00 A;  5DLV A;  3TX0 A;  1N2L A;  1ZED A;  1B8J A;  2GLQ A;  4NWX A;  3Q3Q A;  3IGY B;  1ZEF A;  4LR7 A;  2W5R A;  1KH7 A;  4LRC A;  5LRN A;  1Y6V A;  3UN2 A;  1ELX A;  5TJ3 A;  2XRG A;  1ED8 A;  4QAX A;  1Y7A A;  3CMR A;  1KHN A;  3TG0 A;  4CXK A;  3LXQ A;  1ALJ A;  1ELY A;  1SHQ A;  1ZEB A;  5HRT A;  3BDH A;  4KAV A;  3WBH A;  3OT9 A;  3TWZ A;  5INH A;  3M8Z A;  2W5V A;  1EI6 A;  4CYR A;  5IJQ A;  2W8S A;  4KJD A;  2QZU A;  4KM4 A;  5GRR A;  4ZG9 A;  2W5T A;  3MK2 A;  1E2S P;  3T02 A;  3E2D A;  3WAW A;  3NKP A;  5K4P A;  3A52 A;  3MK0 A;  4MY4 A;  3IDD A;  3SZY A;  1E1Z P;  4UPI A;  4LQY A;  3BDG A;  4UOO A;  2GA3 A;  1E3C P;  2XR9 A;  3NVL A;  2IFY A;  4LRE A;  3M7V A;  4YR1 A;  3M8W A;  4TN0 A;  2W8D A;  3IGZ B;  1KH4 A;  4ZG7 A;  5LIA A;  1AJD A;  4MHX A;  4GTX A;  3BDG B;  3DPC A;  3UNY A;  3WAY A;  1ALH A;  1K7H A;  2G9Y A;  4LRF A;  4LRA A;  1HJK A;  2X98 A;  3UN5 A;  4NWJ A;  5L0E A;  5DLT A;  2GSO A;  4CXU A;  4LR9 A;  1URB A;  4UOR A; 
#chains in the Genus database with same CATH topology
 4UPK A;  1ALI A;  3B5Q A;  4ZG6 A;  2W5W A;  3NKR A;  2IUC B;  4LRB A;  4B56 A;  4CYS A;  3UN3 A;  1O99 A;  5KXA A;  4UPH A;  5IJS A;  4GTZ A;  4ZGA A;  4CXS A;  1AJB A;  5LRM A;  3DYC A;  4N7T A;  4MIV A;  1FSU A;  1KHK A;  3ED4 A;  4KAY A;  1EW9 A;  2GSU A;  4GTY A;  2GSN A;  1HDH A;  1E33 P;  5AJ9 A;  3SZZ A;  1ELZ A;  1AJC A;  1KHL A;  1KH9 A;  1EW8 A;  1N2K A;  5L0B A;  1HQA A;  2W5Q A;  4GTW A;  3NKN A;  3KD8 A;  4LR2 A;  2IUC A;  1EJJ A;  2D1G A;  1URA A;  1ED9 A;  4LR8 A;  3WAV A;  3BDF A;  3T01 A;  3M8Y A;  4FDI A;  1AJA A;  1EW2 A;  2RH6 A;  1ANI A;  3NKO A;  2VQR A;  5EGE A;  1AUK A;  4KJG A;  5L0K A;  3WAX A;  4UOP A;  5EGH A;  4UPL A;  1SHN A;  1ANJ A;  5DLW A;  4FDJ A;  2ANH A;  4LRD A;  1ALK A;  5LQQ A;  5GOV A;  1EQJ A;  1P49 A;  3MK1 A;  2W5X A;  3NKM A;  1KHJ A;  1O98 A;  3UO0 A;  2ZKT A;  5C66 A;  2W5S A;  1KH5 A;  3NKQ A;  3T00 A;  5DLV A;  3TX0 A;  1N2L A;  1ZED A;  1B8J A;  2GLQ A;  4NWX A;  3Q3Q A;  3IGY B;  1ZEF A;  4LR7 A;  2W5R A;  1KH7 A;  4LRC A;  5LRN A;  1Y6V A;  3UN2 A;  1ELX A;  5TJ3 A;  2XRG A;  1ED8 A;  4QAX A;  1Y7A A;  3CMR A;  1KHN A;  3TG0 A;  4CXK A;  3LXQ A;  1ALJ A;  1ELY A;  1SHQ A;  1ZEB A;  5HRT A;  3BDH A;  4KAV A;  3WBH A;  3OT9 A;  3TWZ A;  5INH A;  3M8Z A;  2W5V A;  1EI6 A;  4CYR A;  5IJQ A;  2W8S A;  4KJD A;  2QZU A;  4KM4 A;  5GRR A;  4ZG9 A;  2W5T A;  3MK2 A;  1E2S P;  3T02 A;  3E2D A;  3WAW A;  3NKP A;  5K4P A;  3A52 A;  3MK0 A;  4MY4 A;  3IDD A;  3SZY A;  1E1Z P;  4UPI A;  4LQY A;  3BDG A;  4UOO A;  2GA3 A;  1E3C P;  2XR9 A;  3NVL A;  2IFY A;  4LRE A;  3M7V A;  4YR1 A;  3M8W A;  4TN0 A;  2W8D A;  3IGZ B;  1KH4 A;  4ZG7 A;  5LIA A;  1AJD A;  4MHX A;  4GTX A;  3BDG B;  3DPC A;  3UNY A;  3WAY A;  1ALH A;  1K7H A;  2G9Y A;  4LRF A;  4LRA A;  1HJK A;  2X98 A;  3UN5 A;  4NWJ A;  5L0E A;  5DLT A;  2GSO A;  4CXU A;  4LR9 A;  1URB A;  4UOR A; 
#chains in the Genus database with same CATH homology
 4UPK A;  1ALI A;  3B5Q A;  4ZG6 A;  2W5W A;  3NKR A;  2IUC B;  4LRB A;  4B56 A;  4CYS A;  3UN3 A;  1O99 A;  5KXA A;  4UPH A;  5IJS A;  4GTZ A;  4ZGA A;  4CXS A;  1AJB A;  5LRM A;  3DYC A;  4N7T A;  4MIV A;  1FSU A;  1KHK A;  3ED4 A;  4KAY A;  1EW9 A;  2GSU A;  4GTY A;  2GSN A;  1HDH A;  1E33 P;  5AJ9 A;  3SZZ A;  1ELZ A;  1AJC A;  1KHL A;  1KH9 A;  1EW8 A;  1N2K A;  5L0B A;  1HQA A;  2W5Q A;  4GTW A;  3NKN A;  3KD8 A;  4LR2 A;  2IUC A;  1EJJ A;  2D1G A;  1URA A;  1ED9 A;  4LR8 A;  3WAV A;  3BDF A;  3T01 A;  3M8Y A;  4FDI A;  1AJA A;  1EW2 A;  2RH6 A;  1ANI A;  3NKO A;  2VQR A;  5EGE A;  1AUK A;  4KJG A;  5L0K A;  3WAX A;  4UOP A;  5EGH A;  4UPL A;  1SHN A;  1ANJ A;  5DLW A;  4FDJ A;  2ANH A;  4LRD A;  1ALK A;  5LQQ A;  5GOV A;  1EQJ A;  1P49 A;  3MK1 A;  2W5X A;  3NKM A;  1KHJ A;  1O98 A;  3UO0 A;  2ZKT A;  5C66 A;  2W5S A;  1KH5 A;  3NKQ A;  3T00 A;  5DLV A;  3TX0 A;  1N2L A;  1ZED A;  1B8J A;  2GLQ A;  4NWX A;  3Q3Q A;  3IGY B;  1ZEF A;  4LR7 A;  2W5R A;  1KH7 A;  4LRC A;  5LRN A;  1Y6V A;  3UN2 A;  1ELX A;  5TJ3 A;  2XRG A;  1ED8 A;  4QAX A;  1Y7A A;  3CMR A;  1KHN A;  3TG0 A;  4CXK A;  3LXQ A;  1ALJ A;  1ELY A;  1SHQ A;  1ZEB A;  5HRT A;  3BDH A;  4KAV A;  3WBH A;  3OT9 A;  3TWZ A;  5INH A;  3M8Z A;  2W5V A;  1EI6 A;  4CYR A;  5IJQ A;  2W8S A;  4KJD A;  2QZU A;  4KM4 A;  5GRR A;  4ZG9 A;  2W5T A;  3MK2 A;  1E2S P;  3T02 A;  3E2D A;  3WAW A;  3NKP A;  5K4P A;  3A52 A;  3MK0 A;  4MY4 A;  3IDD A;  3SZY A;  1E1Z P;  4UPI A;  4LQY A;  3BDG A;  4UOO A;  2GA3 A;  1E3C P;  2XR9 A;  3NVL A;  2IFY A;  4LRE A;  3M7V A;  4YR1 A;  3M8W A;  4TN0 A;  2W8D A;  3IGZ B;  1KH4 A;  4ZG7 A;  5LIA A;  1AJD A;  4MHX A;  4GTX A;  3BDG B;  3DPC A;  3UNY A;  3WAY A;  1ALH A;  1K7H A;  2G9Y A;  4LRF A;  4LRA A;  1HJK A;  2X98 A;  3UN5 A;  4NWJ A;  5L0E A;  5DLT A;  2GSO A;  4CXU A;  4LR9 A;  1URB A;  4UOR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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