2D1GA

Structure of francisella tularensis acid phosphatase a (acpa) bound to orthovanadate
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
Knots found
sequence length
485
structure length
481
Chain Sequence
NSKPNDYGTLQKLFNNANTLKTTTPIKHVVIIFQENNSFDRYFGMYPNAKNPEGEPKFVAKENTPNVNGLTKQLLENNPNTKNPYRLDRNFQPCSQNHEYHQEISSFNGGLMNKFVEHGGHDNDTYKQNCDGQVMGYYDGNTVTALWNYAQNFALNDNTFGTTFGPSTPGALNLVAGANGPAMSPSGNLENIENNYIIDDPNPYYDDCSYGTSKSGDTNTAVAKITDGYNIGHYLTQKGITWGWFQGGFKPTSYSGKTAICDAMSTNKFGVKSRDYIPHHEPFNYWKETSNPHHLAPSDDKYIGSNDQANHQYDISEFWKALDQNNMPAVSYLKAPGYQDGHGGYSNPLDEQEWLVNTINRIQQSKDWDSTAIIIIYDDSDGDYDHVYSPKSQFSDIKGRQGYGPRLPMLVISPYAKANYVDHSLLNQASVLKFIEYNWGIGSVSKYSNDKYSNNILNMFDFNKEQKTLKLILDPKTGLVM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of Francisella tularensis AcpA: prototype of a unique superfamily of acid phosphatases and phospholipases C
pubmed doi rcsb
molecule tags Hydrolase
source organism Francisella tularensis subsp. novicida
molecule keywords acid phosphatase
total genus 180
structure length 481
sequence length 485
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.2: Acid phosphatase.
pdb deposition date 2005-08-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04185 Phosphoesterase Phosphoesterase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2d1gA02
1N2KA 2W5WA 4MHXA 1URBA 3M7VA 3MK0A 3UN5A 2W5XA 1AJDA 4GTZA 3BDGB 5AJ9A 5DLVA 2D1GA 2ANHA 4N7TA 5DLWA 2GA3A 5INHA 3A52A 4CXKA 2W5QA 4ZGAA 1HQAA 1N2LA 2W5VA 3TWZA 3M8WA 4KJDA 1EW9A 2GLQA 4KM4A 3WBHA 3NVLA 1EQJA 2X98A 3WAYA 4LR2A 4NWXA 5GOVA 5LIAA 4LR8A 1AJCA 1EW8A 3DPCA 4CYSA 3UO0A 4ZG7A 1ELYA 2W5TA 4CXSA 4CYRA 4LRAA 5LRMA 4YR1A 3SZZA 1EW2A 4LR9A 3IDDA 3T01A 2VQRA 2QZUA 2W8DA 5EGEA 2W5SA 1E33P 4LRCA 3UN2A 2GSOA 4UPIA 1ZEBA 4CXUA 1ALHA 5IJQA 3E2DA 3NKRA 3OT9A 1KHJA 4B56A 3UNYA 3ED4A 4UPKA 2RH6A 4UPHA 3UN3A 1ALKA 2XR9A 4GTYA 1B8JA 1HDHA 3SZYA 2XRGA 1ZEFA 1ZEDA 3M8ZA 3NKQA 2IUCA 3WAXA 3CMRA 4UPLA 1Y6VA 1AJAA 3WAWA 1ELZA 2G9YA 4UOOA 3B5QA 4LRDA 1E2SP 1O98A 1KH9A 2W5RA 1SHQA 4KAYA 4ZG6A 1FSUA 1P49A 2IFYA 3BDFA 1ANJA 2GSUA 4LRFA 3KD8A 4MY4A 5TJ3A 1ALJA 1KHKA 1SHNA 3TX0A 4GTXA 2GSNA 1EI6A 1KH5A 4LQYA 2ZKTA 1ED9A 4UOPA 1HJKA 1AJBA 5DLTA 3BDGA 4LR7A 1E1ZP 3TG0A 5L0BA 5HRTA 1KH4A 1EJJA 1ELXA 4QAXA 1K7HA 3NKMA 4GTWA 1KHLA 4MIVA 3IGYB 5K4PA 1E3CP 4KJGA 5L0EA 5EGHA 5KXAA 3WAVA 3MK2A 3Q3QA 5LRNA 5LQQA 3LXQA 3MK1A 3NKOA 1ALIA 1Y7AA 4LRBA 3DYCA 3NKNA 1AUKA 2IUCB 3BDHA 5IJSA 3T02A 4KAVA 4LREA 4UORA 5L0KA 3M8YA 1KH7A 4FDJA 3NKPA 1O99A 1KHNA 1ANIA 1ED8A 2W8SA 3IGZB 4ZG9A 1URAA 5C66A 4FDIA 3T00A 5GRRA 4TN0A 4NWJA
chains in the Genus database with same CATH superfamily
1N2KA 2W5WA 4MHXA 1URBA 3M7VA 3MK0A 3UN5A 2W5XA 1AJDA 4GTZA 3BDGB 5AJ9A 5DLVA 2D1GA 2ANHA 4N7TA 5DLWA 2GA3A 5INHA 3A52A 4CXKA 2W5QA 4ZGAA 1HQAA 1N2LA 2W5VA 3TWZA 3M8WA 4KJDA 1EW9A 2GLQA 4KM4A 3WBHA 3NVLA 1EQJA 2X98A 3WAYA 4LR2A 4NWXA 5GOVA 5LIAA 4LR8A 1AJCA 1EW8A 3DPCA 4CYSA 3UO0A 4ZG7A 1ELYA 2W5TA 4CXSA 4CYRA 4LRAA 5LRMA 4YR1A 3SZZA 1EW2A 4LR9A 3IDDA 3T01A 2VQRA 2QZUA 2W8DA 5EGEA 2W5SA 1E33P 4LRCA 3UN2A 2GSOA 4UPIA 1ZEBA 4CXUA 1ALHA 5IJQA 3E2DA 3NKRA 3OT9A 1KHJA 4B56A 3UNYA 3ED4A 4UPKA 2RH6A 4UPHA 3UN3A 1ALKA 2XR9A 4GTYA 1B8JA 1HDHA 3SZYA 2XRGA 1ZEFA 1ZEDA 3M8ZA 3NKQA 2IUCA 3WAXA 3CMRA 4UPLA 1Y6VA 1AJAA 3WAWA 1ELZA 2G9YA 4UOOA 3B5QA 4LRDA 1E2SP 1O98A 1KH9A 2W5RA 1SHQA 4KAYA 4ZG6A 1FSUA 1P49A 2IFYA 3BDFA 1ANJA 2GSUA 4LRFA 3KD8A 4MY4A 5TJ3A 1ALJA 1KHKA 1SHNA 3TX0A 4GTXA 2GSNA 1EI6A 1KH5A 4LQYA 2ZKTA 1ED9A 4UOPA 1HJKA 1AJBA 5DLTA 3BDGA 4LR7A 1E1ZP 3TG0A 5L0BA 5HRTA 1KH4A 1EJJA 1ELXA 4QAXA 1K7HA 3NKMA 4GTWA 1KHLA 4MIVA 3IGYB 5K4PA 1E3CP 4KJGA 5L0EA 5EGHA 5KXAA 3WAVA 3MK2A 3Q3QA 5LRNA 5LQQA 3LXQA 3MK1A 3NKOA 1ALIA 1Y7AA 4LRBA 3DYCA 3NKNA 1AUKA 2IUCB 3BDHA 5IJSA 3T02A 4KAVA 4LREA 4UORA 5L0KA 3M8YA 1KH7A 4FDJA 3NKPA 1O99A 1KHNA 1ANIA 1ED8A 2W8SA 3IGZB 4ZG9A 1URAA 5C66A 4FDIA 3T00A 5GRRA 4TN0A 4NWJA
chains in the Genus database with same CATH topology
1N2KA 2W5WA 4MHXA 1URBA 3M7VA 3MK0A 3UN5A 2W5XA 1AJDA 4GTZA 3BDGB 5AJ9A 5DLVA 2D1GA 2ANHA 4N7TA 5DLWA 2GA3A 5INHA 3A52A 4CXKA 2W5QA 4ZGAA 1HQAA 1N2LA 2W5VA 3TWZA 3M8WA 4KJDA 1EW9A 2GLQA 4KM4A 3WBHA 3NVLA 1EQJA 2X98A 3WAYA 4LR2A 4NWXA 5GOVA 5LIAA 4LR8A 1AJCA 1EW8A 3DPCA 4CYSA 3UO0A 4ZG7A 1ELYA 2W5TA 4CXSA 4CYRA 4LRAA 5LRMA 4YR1A 3SZZA 1EW2A 4LR9A 3IDDA 3T01A 2VQRA 2QZUA 2W8DA 5EGEA 2W5SA 1E33P 4LRCA 3UN2A 2GSOA 4UPIA 1ZEBA 4CXUA 1ALHA 5IJQA 3E2DA 3NKRA 3OT9A 1KHJA 4B56A 3UNYA 3ED4A 4UPKA 2RH6A 4UPHA 3UN3A 1ALKA 2XR9A 4GTYA 1B8JA 1HDHA 3SZYA 2XRGA 1ZEFA 1ZEDA 3M8ZA 3NKQA 2IUCA 3WAXA 3CMRA 4UPLA 1Y6VA 1AJAA 3WAWA 1ELZA 2G9YA 4UOOA 3B5QA 4LRDA 1E2SP 1O98A 1KH9A 2W5RA 1SHQA 4KAYA 4ZG6A 1FSUA 1P49A 2IFYA 3BDFA 1ANJA 2GSUA 4LRFA 3KD8A 4MY4A 5TJ3A 1ALJA 1KHKA 1SHNA 3TX0A 4GTXA 2GSNA 1EI6A 1KH5A 4LQYA 2ZKTA 1ED9A 4UOPA 1HJKA 1AJBA 5DLTA 3BDGA 4LR7A 1E1ZP 3TG0A 5L0BA 5HRTA 1KH4A 1EJJA 1ELXA 4QAXA 1K7HA 3NKMA 4GTWA 1KHLA 4MIVA 3IGYB 5K4PA 1E3CP 4KJGA 5L0EA 5EGHA 5KXAA 3WAVA 3MK2A 3Q3QA 5LRNA 5LQQA 3LXQA 3MK1A 3NKOA 1ALIA 1Y7AA 4LRBA 3DYCA 3NKNA 1AUKA 2IUCB 3BDHA 5IJSA 3T02A 4KAVA 4LREA 4UORA 5L0KA 3M8YA 1KH7A 4FDJA 3NKPA 1O99A 1KHNA 1ANIA 1ED8A 2W8SA 3IGZB 4ZG9A 1URAA 5C66A 4FDIA 3T00A 5GRRA 4TN0A 4NWJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N2K A;  2W5W A;  4MHX A;  1URB A;  3M7V A;  3MK0 A;  3UN5 A;  2W5X A;  1AJD A;  4GTZ A;  3BDG B;  5AJ9 A;  5DLV A;  2D1G A;  2ANH A;  4N7T A;  5DLW A;  2GA3 A;  5INH A;  3A52 A;  4CXK A;  2W5Q A;  4ZGA A;  1HQA A;  1N2L A;  2W5V A;  3TWZ A;  3M8W A;  4KJD A;  1EW9 A;  2GLQ A;  4KM4 A;  3WBH A;  3NVL A;  1EQJ A;  2X98 A;  3WAY A;  4LR2 A;  4NWX A;  5GOV A;  5LIA A;  4LR8 A;  1AJC A;  1EW8 A;  3DPC A;  4CYS A;  3UO0 A;  4ZG7 A;  1ELY A;  2W5T A;  4CXS A;  4CYR A;  4LRA A;  5LRM A;  4YR1 A;  3SZZ A;  1EW2 A;  4LR9 A;  3IDD A;  3T01 A;  2VQR A;  2QZU A;  2W8D A;  5EGE A;  2W5S A;  1E33 P;  4LRC A;  3UN2 A;  2GSO A;  4UPI A;  1ZEB A;  4CXU A;  1ALH A;  5IJQ A;  3E2D A;  3NKR A;  3OT9 A;  1KHJ A;  4B56 A;  3UNY A;  3ED4 A;  4UPK A;  2RH6 A;  4UPH A;  3UN3 A;  1ALK A;  2XR9 A;  4GTY A;  1B8J A;  1HDH A;  3SZY A;  2XRG A;  1ZEF A;  1ZED A;  3M8Z A;  3NKQ A;  2IUC A;  3WAX A;  3CMR A;  4UPL A;  1Y6V A;  1AJA A;  3WAW A;  1ELZ A;  2G9Y A;  4UOO A;  3B5Q A;  4LRD A;  1E2S P;  1O98 A;  1KH9 A;  2W5R A;  1SHQ A;  4KAY A;  4ZG6 A;  1FSU A;  1P49 A;  2IFY A;  3BDF A;  1ANJ A;  2GSU A;  4LRF A;  3KD8 A;  4MY4 A;  5TJ3 A;  1ALJ A;  1KHK A;  1SHN A;  3TX0 A;  4GTX A;  2GSN A;  1EI6 A;  1KH5 A;  4LQY A;  2ZKT A;  1ED9 A;  4UOP A;  1HJK A;  1AJB A;  5DLT A;  3BDG A;  4LR7 A;  1E1Z P;  3TG0 A;  5L0B A;  5HRT A;  1KH4 A;  1EJJ A;  1ELX A;  4QAX A;  1K7H A;  3NKM A;  4GTW A;  1KHL A;  4MIV A;  3IGY B;  5K4P A;  1E3C P;  4KJG A;  5L0E A;  5EGH A;  5KXA A;  3WAV A;  3MK2 A;  3Q3Q A;  5LRN A;  5LQQ A;  3LXQ A;  3MK1 A;  3NKO A;  1ALI A;  1Y7A A;  4LRB A;  3DYC A;  3NKN A;  1AUK A;  2IUC B;  3BDH A;  5IJS A;  3T02 A;  4KAV A;  4LRE A;  4UOR A;  5L0K A;  3M8Y A;  1KH7 A;  4FDJ A;  3NKP A;  1O99 A;  1KHN A;  1ANI A;  1ED8 A;  2W8S A;  3IGZ B;  4ZG9 A;  1URA A;  5C66 A;  4FDI A;  3T00 A;  5GRR A;  4TN0 A;  4NWJ A; 
#chains in the Genus database with same CATH topology
 1N2K A;  2W5W A;  4MHX A;  1URB A;  3M7V A;  3MK0 A;  3UN5 A;  2W5X A;  1AJD A;  4GTZ A;  3BDG B;  5AJ9 A;  5DLV A;  2D1G A;  2ANH A;  4N7T A;  5DLW A;  2GA3 A;  5INH A;  3A52 A;  4CXK A;  2W5Q A;  4ZGA A;  1HQA A;  1N2L A;  2W5V A;  3TWZ A;  3M8W A;  4KJD A;  1EW9 A;  2GLQ A;  4KM4 A;  3WBH A;  3NVL A;  1EQJ A;  2X98 A;  3WAY A;  4LR2 A;  4NWX A;  5GOV A;  5LIA A;  4LR8 A;  1AJC A;  1EW8 A;  3DPC A;  4CYS A;  3UO0 A;  4ZG7 A;  1ELY A;  2W5T A;  4CXS A;  4CYR A;  4LRA A;  5LRM A;  4YR1 A;  3SZZ A;  1EW2 A;  4LR9 A;  3IDD A;  3T01 A;  2VQR A;  2QZU A;  2W8D A;  5EGE A;  2W5S A;  1E33 P;  4LRC A;  3UN2 A;  2GSO A;  4UPI A;  1ZEB A;  4CXU A;  1ALH A;  5IJQ A;  3E2D A;  3NKR A;  3OT9 A;  1KHJ A;  4B56 A;  3UNY A;  3ED4 A;  4UPK A;  2RH6 A;  4UPH A;  3UN3 A;  1ALK A;  2XR9 A;  4GTY A;  1B8J A;  1HDH A;  3SZY A;  2XRG A;  1ZEF A;  1ZED A;  3M8Z A;  3NKQ A;  2IUC A;  3WAX A;  3CMR A;  4UPL A;  1Y6V A;  1AJA A;  3WAW A;  1ELZ A;  2G9Y A;  4UOO A;  3B5Q A;  4LRD A;  1E2S P;  1O98 A;  1KH9 A;  2W5R A;  1SHQ A;  4KAY A;  4ZG6 A;  1FSU A;  1P49 A;  2IFY A;  3BDF A;  1ANJ A;  2GSU A;  4LRF A;  3KD8 A;  4MY4 A;  5TJ3 A;  1ALJ A;  1KHK A;  1SHN A;  3TX0 A;  4GTX A;  2GSN A;  1EI6 A;  1KH5 A;  4LQY A;  2ZKT A;  1ED9 A;  4UOP A;  1HJK A;  1AJB A;  5DLT A;  3BDG A;  4LR7 A;  1E1Z P;  3TG0 A;  5L0B A;  5HRT A;  1KH4 A;  1EJJ A;  1ELX A;  4QAX A;  1K7H A;  3NKM A;  4GTW A;  1KHL A;  4MIV A;  3IGY B;  5K4P A;  1E3C P;  4KJG A;  5L0E A;  5EGH A;  5KXA A;  3WAV A;  3MK2 A;  3Q3Q A;  5LRN A;  5LQQ A;  3LXQ A;  3MK1 A;  3NKO A;  1ALI A;  1Y7A A;  4LRB A;  3DYC A;  3NKN A;  1AUK A;  2IUC B;  3BDH A;  5IJS A;  3T02 A;  4KAV A;  4LRE A;  4UOR A;  5L0K A;  3M8Y A;  1KH7 A;  4FDJ A;  3NKP A;  1O99 A;  1KHN A;  1ANI A;  1ED8 A;  2W8S A;  3IGZ B;  4ZG9 A;  1URA A;  5C66 A;  4FDI A;  3T00 A;  5GRR A;  4TN0 A;  4NWJ A; 
#chains in the Genus database with same CATH homology
 1N2K A;  2W5W A;  4MHX A;  1URB A;  3M7V A;  3MK0 A;  3UN5 A;  2W5X A;  1AJD A;  4GTZ A;  3BDG B;  5AJ9 A;  5DLV A;  2D1G A;  2ANH A;  4N7T A;  5DLW A;  2GA3 A;  5INH A;  3A52 A;  4CXK A;  2W5Q A;  4ZGA A;  1HQA A;  1N2L A;  2W5V A;  3TWZ A;  3M8W A;  4KJD A;  1EW9 A;  2GLQ A;  4KM4 A;  3WBH A;  3NVL A;  1EQJ A;  2X98 A;  3WAY A;  4LR2 A;  4NWX A;  5GOV A;  5LIA A;  4LR8 A;  1AJC A;  1EW8 A;  3DPC A;  4CYS A;  3UO0 A;  4ZG7 A;  1ELY A;  2W5T A;  4CXS A;  4CYR A;  4LRA A;  5LRM A;  4YR1 A;  3SZZ A;  1EW2 A;  4LR9 A;  3IDD A;  3T01 A;  2VQR A;  2QZU A;  2W8D A;  5EGE A;  2W5S A;  1E33 P;  4LRC A;  3UN2 A;  2GSO A;  4UPI A;  1ZEB A;  4CXU A;  1ALH A;  5IJQ A;  3E2D A;  3NKR A;  3OT9 A;  1KHJ A;  4B56 A;  3UNY A;  3ED4 A;  4UPK A;  2RH6 A;  4UPH A;  3UN3 A;  1ALK A;  2XR9 A;  4GTY A;  1B8J A;  1HDH A;  3SZY A;  2XRG A;  1ZEF A;  1ZED A;  3M8Z A;  3NKQ A;  2IUC A;  3WAX A;  3CMR A;  4UPL A;  1Y6V A;  1AJA A;  3WAW A;  1ELZ A;  2G9Y A;  4UOO A;  3B5Q A;  4LRD A;  1E2S P;  1O98 A;  1KH9 A;  2W5R A;  1SHQ A;  4KAY A;  4ZG6 A;  1FSU A;  1P49 A;  2IFY A;  3BDF A;  1ANJ A;  2GSU A;  4LRF A;  3KD8 A;  4MY4 A;  5TJ3 A;  1ALJ A;  1KHK A;  1SHN A;  3TX0 A;  4GTX A;  2GSN A;  1EI6 A;  1KH5 A;  4LQY A;  2ZKT A;  1ED9 A;  4UOP A;  1HJK A;  1AJB A;  5DLT A;  3BDG A;  4LR7 A;  1E1Z P;  3TG0 A;  5L0B A;  5HRT A;  1KH4 A;  1EJJ A;  1ELX A;  4QAX A;  1K7H A;  3NKM A;  4GTW A;  1KHL A;  4MIV A;  3IGY B;  5K4P A;  1E3C P;  4KJG A;  5L0E A;  5EGH A;  5KXA A;  3WAV A;  3MK2 A;  3Q3Q A;  5LRN A;  5LQQ A;  3LXQ A;  3MK1 A;  3NKO A;  1ALI A;  1Y7A A;  4LRB A;  3DYC A;  3NKN A;  1AUK A;  2IUC B;  3BDH A;  5IJS A;  3T02 A;  4KAV A;  4LRE A;  4UOR A;  5L0K A;  3M8Y A;  1KH7 A;  4FDJ A;  3NKP A;  1O99 A;  1KHN A;  1ANI A;  1ED8 A;  2W8S A;  3IGZ B;  4ZG9 A;  1URA A;  5C66 A;  4FDI A;  3T00 A;  5GRR A;  4TN0 A;  4NWJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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