2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
molecule tags Rna methyltransferase
source organism Aquifex aeolicus
molecule keywords UPF0088 protein aq_165
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
4YQSA 1MXIA 3E5YA 4J3CA 1IPAA 3AXZA 3N4KA 4JAKA 4YVGA 1GZ0A 1J85A 3ILKA 4YPXA 1Z85A 3L8UA 4YQQA 4YQCA 4YQ6A 4X3LA 4X3MA 4H3YA 1V2XA 4YQ5A 4YQ3A 2V3KA 4H3ZA 5FAIA 4IG6A 2QWVA 3O7BA 1VH0A 4YQDA 2V3JA 3AIAA 2NWAA 5D9FA 4YQIA 4YQGA 3KNUA 3QUVA 4YQAA 4YQPA 3KY7A 1VHKA 4YQTA 3OIJA 4CNGA 3BBDA 5GM8A 1VHYA 1OY5A 4YQ8A 1ZJRA 4L69A 4YQNA 1UAJA 1UAMA 4FAKA 2CX8A 5GMBA 1UAKA 4E8BA 4XBOA 3AI9X 1NS5A 3DCMX 4CNEA 4YVIA 3BBHA 4YPYA 2QMMA 4RG1A 2O3AA 3IC6A 4PZKA 2I6DA 3KTYA 4CNDA 4YQ4A 1X7OA 3IEFA 4YQ0A 4YQKA 4YQLA 1TO0A 2YY8A 5GMCA 2EGVA 1X7PA 4YVHA 3BBEA 2EGWA 4YVKA 3GYQA 4KDZA 3N4JA 3ONPA 4YQ9A 4YQRA 4YVJA 3NK6A 1NXZA 4YQ2A 2HA8A 1V6ZA 4YQ1A 5CO4A 2Z0YA 4CNFA 3KW2A 3OINA 4MCCA 4YQOA 4JALA 1P9PA 1O6DA 4YPZA 4YQJA 4YQ7A 1UALA 3NK7A 1K3RA 3OIIA 4MCDA 4YQBA 4YPWA 4KGNA 4MCBA
chains in the Genus database with same CATH superfamily
4YQSA 1MXIA 3E5YA 1ZJWA 4J3CA 4IO9S 4H3SA 1IPAA 3AXZA 3PIPS 3N4KA 4JAKA 4YVGA 3DLLS 1GZ0A 2RE8A 1J85A 3ILKA 4YPXA 4FMWA 5GADW 1Z85A 5DM6S 3L8UA 1GTRA 2PI8A 4YQQA 4YQCA 4H4KA 4YQ6A 3W2VB 4X3LA 4X3MA 4JYZA 2ZJRS 4H3YA 5BNZA 1V2XA 4YQ5A 4YQ3A 2V3KA 4H3ZA 5FAIA 4IG6A 4WFAS 2HZ7A 2QWVA 2PNWA 4WFBS 3W2WB 3O7BA 1VH0A 1NYLA 4YQDA 4UY88 2V3JA 3AIAA 2NWAA 5D9FA 4YQIA 4YQGA 3KNUA 3QUVA 4YQAA 2G5DA 4YQPA 3KY7A 1VHKA 4YQTA 3OIJA 4CNGA 3BBDA 5GM8A 1VHYA 1OY5A 4YQ8A 1ZJRA 4L69A 4YQNA 1UAJA 1UAMA 4FAKA 1QRUA 2CX8A 5GMBA 1UAKA 4WFNS 4E8BA 4XBOA 1D6KA 4JWHA 5DM7S 3AI9X 1EUQA 4IOAS 1NS5A 3DCMX 2G6GA 2ZJPS 4CNEA 4YVIA 3BBHA 4YPYA 2QMMA 4RG1A 1EXDA 1DFUP 4P2BA 1O0CA 2O3AA 5HL7S 3IC6A 4PZKA 2I6DA 4JXXA 3KTYA 4CNDA 2PICA 4YQ4A 1X7OA 3IEFA 4YQ0A 4YQKA 4YQLA 1TO0A 2YY8A 5GMCA 2EGVA 5GAGW 1QTQA 2AE0X 1EUYA 1X7PA 4JWJA 3CZBA 4YVHA 3BBEA 2GAEA 2EGWA 5GAHW 4YVKA 4IOCS 4JXZA 3GYQA 1FEUA 2ZJQS 2RD2A 4WF9S 3N4JA 3ONPA 4KDZA 4YQ9A 1QRSA 3NK6A 4YQRA 1NXZA 4YQ2A 1QRTA 2HA8A 1V6ZA 4YQ1A 5CO4A 2Z0YA 4CNFA 1O0BA 3J7ZV 3KW2A 1GTSA 3OINA 4MCCA 4YQOA 4YVJA 2PJJA 5IZNA 3PIOS 4JWFA 4JALA 1P9PA 1O6DA 4YPZA 4YQJA 4U67S 4YQ7A 1UALA 5JVGS 3NK7A 3CF5S 3X1LB 1K3RA 3OIIA 3AIIA 4MCDA 5JVHS 5GAEW 4JWGA 4YQBA 1B75A 4YPWA 4V194 4KGNA 1UDXA 4MCBA 4WCES
chains in the Genus database with same CATH topology
4YQSA 1MXIA 3E5YA 4J3CA 1IPAA 3AXZA 3N4KA 4JAKA 4YVGA 1GZ0A 1J85A 3ILKA 4YPXA 4FMWA 1Z85A 3L8UA 4YQQA 4YQCA 4YQ6A 4X3LA 4X3MA 4H3YA 1V2XA 4YQ5A 4YQ3A 2V3KA 4H3ZA 5FAIA 4IG6A 2QWVA 3O7BA 1VH0A 4YQDA 2V3JA 3AIAA 2NWAA 5D9FA 4YQIA 4YQGA 3KNUA 3QUVA 4YQAA 4YQPA 3KY7A 1VHKA 4YQTA 3OIJA 4CNGA 3BBDA 5GM8A 1VHYA 1OY5A 4YQ8A 1ZJRA 4L69A 4YQNA 1UAJA 1UAMA 4FAKA 2CX8A 5GMBA 1UAKA 4E8BA 4XBOA 4JWHA 3AI9X 1NS5A 3DCMX 4CNEA 4YVIA 3BBHA 4YPYA 2QMMA 4RG1A 2O3AA 3IC6A 4PZKA 2I6DA 3KTYA 4CNDA 4YQ4A 1X7OA 3IEFA 4YQ0A 4YQKA 4YQLA 1TO0A 2YY8A 5GMCA 2EGVA 1X7PA 4JWJA 4YVHA 3BBEA 2EGWA 4YVKA 3GYQA 4KDZA 3N4JA 3ONPA 4YQ9A 4YQRA 4YVJA 3NK6A 1NXZA 4YQ2A 2HA8A 1V6ZA 4YQ1A 5CO4A 2Z0YA 4CNFA 3KW2A 3OINA 4MCCA 4YQOA 4JWFA 4JALA 1P9PA 1O6DA 4YPZA 4YQJA 4YQ7A 1UALA 3NK7A 1K3RA 3OIIA 4MCDA 4JWGA 4YQBA 4YPWA 4KGNA 4MCBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQS A;  1MXI A;  3E5Y A;  4J3C A;  1IPA A;  3AXZ A;  3N4K A;  4JAK A;  4YVG A;  1GZ0 A;  1J85 A;  3ILK A;  4YPX A;  1Z85 A;  3L8U A;  4YQQ A;  4YQC A;  4YQ6 A;  4X3L A;  4X3M A;  4H3Y A;  1V2X A;  4YQ5 A;  4YQ3 A;  2V3K A;  4H3Z A;  5FAI A;  4IG6 A;  2QWV A;  3O7B A;  1VH0 A;  4YQD A;  2V3J A;  3AIA A;  2NWA A;  5D9F A;  4YQI A;  4YQG A;  3KNU A;  3QUV A;  4YQA A;  4YQP A;  3KY7 A;  1VHK A;  4YQT A;  3OIJ A;  4CNG A;  3BBD A;  5GM8 A;  1VHY A;  1OY5 A;  4YQ8 A;  1ZJR A;  4L69 A;  4YQN A;  1UAJ A;  1UAM A;  4FAK A;  2CX8 A;  5GMB A;  1UAK A;  4E8B A;  4XBO A;  3AI9 X;  1NS5 A;  3DCM X;  4CNE A;  4YVI A;  3BBH A;  4YPY A;  2QMM A;  4RG1 A;  2O3A A;  3IC6 A;  4PZK A;  2I6D A;  3KTY A;  4CND A;  4YQ4 A;  1X7O A;  3IEF A;  4YQ0 A;  4YQK A;  4YQL A;  1TO0 A;  2YY8 A;  5GMC A;  2EGV A;  1X7P A;  4YVH A;  3BBE A;  2EGW A;  4YVK A;  3GYQ A;  4KDZ A;  3N4J A;  3ONP A;  4YQ9 A;  4YQR A;  4YVJ A;  3NK6 A;  1NXZ A;  4YQ2 A;  2HA8 A;  1V6Z A;  4YQ1 A;  5CO4 A;  2Z0Y A;  4CNF A;  3KW2 A;  3OIN A;  4MCC A;  4YQO A;  4JAL A;  1P9P A;  1O6D A;  4YPZ A;  4YQJ A;  4YQ7 A;  1UAL A;  3NK7 A;  1K3R A;  3OII A;  4MCD A;  4YQB A;  4YPW A;  4KGN A;  4MCB A; 
#chains in the Genus database with same CATH topology
 4YQS A;  1MXI A;  3E5Y A;  1ZJW A;  4J3C A;  4IO9 S;  4H3S A;  1IPA A;  3AXZ A;  3PIP S;  3N4K A;  4JAK A;  4YVG A;  3DLL S;  1GZ0 A;  2RE8 A;  1J85 A;  3ILK A;  4YPX A;  4FMW A;  5GAD W;  1Z85 A;  5DM6 S;  3L8U A;  1GTR A;  2PI8 A;  4YQQ A;  4YQC A;  4H4K A;  4YQ6 A;  3W2V B;  4X3L A;  4X3M A;  4JYZ A;  2ZJR S;  4H3Y A;  5BNZ A;  1V2X A;  4YQ5 A;  4YQ3 A;  2V3K A;  4H3Z A;  5FAI A;  4IG6 A;  4WFA S;  2HZ7 A;  2QWV A;  2PNW A;  4WFB S;  3W2W B;  3O7B A;  1VH0 A;  1NYL A;  4YQD A;  4UY8 8;  2V3J A;  3AIA A;  2NWA A;  5D9F A;  4YQI A;  4YQG A;  3KNU A;  3QUV A;  4YQA A;  2G5D A;  4YQP A;  3KY7 A;  1VHK A;  4YQT A;  3OIJ A;  4CNG A;  3BBD A;  5GM8 A;  1VHY A;  1OY5 A;  4YQ8 A;  1ZJR A;  4L69 A;  4YQN A;  1UAJ A;  1UAM A;  4FAK A;  1QRU A;  2CX8 A;  5GMB A;  1UAK A;  4WFN S;  4E8B A;  4XBO A;  1D6K A;  4JWH A;  5DM7 S;  3AI9 X;  1EUQ A;  4IOA S;  1NS5 A;  3DCM X;  2G6G A;  2ZJP S;  4CNE A;  4YVI A;  3BBH A;  4YPY A;  2QMM A;  4RG1 A;  1EXD A;  1DFU P;  4P2B A;  1O0C A;  2O3A A;  5HL7 S;  3IC6 A;  4PZK A;  2I6D A;  4JXX A;  3KTY A;  4CND A;  2PIC A;  4YQ4 A;  1X7O A;  3IEF A;  4YQ0 A;  4YQK A;  4YQL A;  1TO0 A;  2YY8 A;  5GMC A;  2EGV A;  5GAG W;  1QTQ A;  2AE0 X;  1EUY A;  1X7P A;  4JWJ A;  3CZB A;  4YVH A;  3BBE A;  2GAE A;  2EGW A;  5GAH W;  4YVK A;  4IOC S;  4JXZ A;  3GYQ A;  1FEU A;  2ZJQ S;  2RD2 A;  4WF9 S;  3N4J A;  3ONP A;  4KDZ A;  4YQ9 A;  1QRS A;  3NK6 A;  4YQR A;  1NXZ A;  4YQ2 A;  1QRT A;  2HA8 A;  1V6Z A;  4YQ1 A;  5CO4 A;  2Z0Y A;  4CNF A;  1O0B A;  3J7Z V;  3KW2 A;  1GTS A;  3OIN A;  4MCC A;  4YQO A;  4YVJ A;  2PJJ A;  5IZN A;  3PIO S;  4JWF A;  4JAL A;  1P9P A;  1O6D A;  4YPZ A;  4YQJ A;  4U67 S;  4YQ7 A;  1UAL A;  5JVG S;  3NK7 A;  3CF5 S;  3X1L B;  1K3R A;  3OII A;  3AII A;  4MCD A;  5JVH S;  5GAE W;  4JWG A;  4YQB A;  1B75 A;  4YPW A;  4V19 4;  4KGN A;  1UDX A;  4MCB A;  4WCE S; 
#chains in the Genus database with same CATH homology
 4YQS A;  1MXI A;  3E5Y A;  4J3C A;  1IPA A;  3AXZ A;  3N4K A;  4JAK A;  4YVG A;  1GZ0 A;  1J85 A;  3ILK A;  4YPX A;  4FMW A;  1Z85 A;  3L8U A;  4YQQ A;  4YQC A;  4YQ6 A;  4X3L A;  4X3M A;  4H3Y A;  1V2X A;  4YQ5 A;  4YQ3 A;  2V3K A;  4H3Z A;  5FAI A;  4IG6 A;  2QWV A;  3O7B A;  1VH0 A;  4YQD A;  2V3J A;  3AIA A;  2NWA A;  5D9F A;  4YQI A;  4YQG A;  3KNU A;  3QUV A;  4YQA A;  4YQP A;  3KY7 A;  1VHK A;  4YQT A;  3OIJ A;  4CNG A;  3BBD A;  5GM8 A;  1VHY A;  1OY5 A;  4YQ8 A;  1ZJR A;  4L69 A;  4YQN A;  1UAJ A;  1UAM A;  4FAK A;  2CX8 A;  5GMB A;  1UAK A;  4E8B A;  4XBO A;  4JWH A;  3AI9 X;  1NS5 A;  3DCM X;  4CNE A;  4YVI A;  3BBH A;  4YPY A;  2QMM A;  4RG1 A;  2O3A A;  3IC6 A;  4PZK A;  2I6D A;  3KTY A;  4CND A;  4YQ4 A;  1X7O A;  3IEF A;  4YQ0 A;  4YQK A;  4YQL A;  1TO0 A;  2YY8 A;  5GMC A;  2EGV A;  1X7P A;  4JWJ A;  4YVH A;  3BBE A;  2EGW A;  4YVK A;  3GYQ A;  4KDZ A;  3N4J A;  3ONP A;  4YQ9 A;  4YQR A;  4YVJ A;  3NK6 A;  1NXZ A;  4YQ2 A;  2HA8 A;  1V6Z A;  4YQ1 A;  5CO4 A;  2Z0Y A;  4CNF A;  3KW2 A;  3OIN A;  4MCC A;  4YQO A;  4JWF A;  4JAL A;  1P9P A;  1O6D A;  4YPZ A;  4YQJ A;  4YQ7 A;  1UAL A;  3NK7 A;  1K3R A;  3OII A;  4MCD A;  4JWG A;  4YQB A;  4YPW A;  4KGN A;  4MCB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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