2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
molecule tags Rna methyltransferase
source organism Aquifex aeolicus
molecule keywords UPF0088 protein aq_165
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
4YQNA 4YQOA 1O6DA 2EGWA 4CNGA 1UAJA 4KGNA 5GMBA 4YQ3A 4YQGA 3BBHA 1VH0A 3NK7A 4YQJA 2QWVA 3BBEA 3BBDA 1NS5A 3KTYA 1X7PA 2HA8A 3E5YA 3O7BA 4MCDA 3KY7A 4H3ZA 4X3LA 4FAKA 4YVJA 5CO4A 4MCBA 5D9FA 4YQSA 3KNUA 4YQPA 3AXZA 4PZKA 4JALA 4YPYA 1VHYA 3OIJA 4YVKA 1X7OA 4YQQA 3N4JA 3ONPA 4JAKA 1MXIA 4YQKA 1K3RA 2CX8A 4J3CA 4X3MA 3L8UA 2Z0YA 1Z85A 4YQ4A 1NXZA 1TO0A 3OIIA 4YQ7A 1IPAA 4KDZA 4YPZA 4YQCA 1V2XA 4YQDA 4YQIA 4E8BA 4YQ5A 2I6DA 3IEFA 5GMCA 2QMMA 3OINA 4YQ8A 4MCCA 4YPWA 4YQTA 1UALA 4YQ0A 3DCMX 2V3KA 1OY5A 3GYQA 2NWAA 1VHKA 5GM8A 1P9PA 4CNEA 3IC6A 4H3YA 4CNDA 4YQ1A 3ILKA 1UAMA 4YQ9A 4YVGA 1UAKA 2V3JA 3QUVA 4RG1A 4YVIA 1ZJRA 2YY8A 4YQLA 2O3AA 3AI9X 3NK6A 2EGVA 3N4KA 4YQRA 3AIAA 1J85A 4IG6A 4YQ2A 4YQ6A 4XBOA 4CNFA 4L69A 1GZ0A 4YVHA 3KW2A 1V6ZA 4YPXA 5FAIA 4YQBA 4YQAA
chains in the Genus database with same CATH superfamily
2GAEA 2G5DA 1EXDA 4H4KA 4YQNA 4YQOA 5GAGW 1O6DA 2EGWA 4CNGA 2ZJRS 1UAJA 4KGNA 5GMBA 1EUYA 4YQ3A 4YQGA 4WFAS 5JVGS 3BBHA 1VH0A 3NK7A 2HZ7A 4H3SA 4YQJA 2QWVA 4JWHA 5GADW 2PICA 3BBEA 3BBDA 1NS5A 3KTYA 1X7PA 2HA8A 3E5YA 5IZNA 3O7BA 3KY7A 4H3ZA 4MCDA 4X3LA 4FAKA 1GTRA 4YVJA 5CO4A 4MCBA 3CF5S 4YQSA 3AIIA 3KNUA 5D9FA 4YQPA 3AXZA 4PZKA 1GTSA 2RD2A 4JALA 4YPYA 1VHYA 3OIJA 4YVKA 1X7OA 4FMWA 2PI8A 4YQQA 3N4JA 3ONPA 4JAKA 3J7ZV 5DM7S 1MXIA 4IO9S 2AE0X 2RE8A 4YQKA 1K3RA 2CX8A 4J3CA 4X3MA 2PJJA 2Z0YA 3L8UA 4V194 1QRUA 1Z85A 3CZBA 4YQ4A 1NXZA 1FEUA 2ZJQS 3X1LB 1TO0A 3OIIA 4YQ7A 4JWFA 1IPAA 4KDZA 1QTQA 4YPZA 5DM6S 4JXZA 5BNZA 4YQCA 4JWJA 1V2XA 4YQDA 4YQIA 4WCES 4E8BA 4YQ5A 2I6DA 3IEFA 5GMCA 5HL7S 2QMMA 1NYLA 3OINA 4YQ8A 4MCCA 4YPWA 4YQTA 2PNWA 1UALA 4YQ0A 3DCMX 2V3KA 1UDXA 1OY5A 3GYQA 3PIOS 1O0CA 1B75A 2NWAA 1DFUP 4U67S 1VHKA 5GM8A 1P9PA 4CNEA 4WF9S 3DLLS 4JXXA 3IC6A 4UY88 4WFBS 4H3YA 1D6KA 4CNDA 4YQ1A 3ILKA 5GAHW 1UAMA 4YQ9A 5JVHS 4YVGA 1UAKA 1O0BA 2V3JA 3QUVA 4RG1A 1QRTA 4YVIA 1ZJRA 2YY8A 1ZJWA 4YQLA 1QRSA 2O3AA 3AI9X 4IOCS 2EGVA 2ZJPS 3W2VB 3N4KA 3NK6A 4YQRA 3AIAA 1J85A 4IG6A 4YQ2A 4YQ6A 3W2WB 4XBOA 4CNFA 4L69A 1GZ0A 4YVHA 1V6ZA 3KW2A 4WFNS 4YPXA 5FAIA 4JYZA 2G6GA 4IOAS 4JWGA 5GAEW 1EUQA 4P2BA 4YQBA 4YQAA 3PIPS
chains in the Genus database with same CATH topology
4YQNA 4YQOA 1O6DA 2EGWA 4CNGA 1UAJA 4KGNA 5GMBA 4YQ3A 4YQGA 3BBHA 1VH0A 3NK7A 4YQJA 2QWVA 4JWHA 3BBEA 3BBDA 1NS5A 3KTYA 1X7PA 2HA8A 3E5YA 3O7BA 4MCDA 3KY7A 4H3ZA 4X3LA 4FAKA 4YVJA 5CO4A 4MCBA 5D9FA 4YQSA 3KNUA 4YQPA 3AXZA 4PZKA 4JALA 4YPYA 1VHYA 3OIJA 4YVKA 1X7OA 4FMWA 4YQQA 3N4JA 3ONPA 4JAKA 1MXIA 4YQKA 1K3RA 2CX8A 4J3CA 4X3MA 3L8UA 2Z0YA 1Z85A 4YQ4A 1NXZA 1TO0A 3OIIA 4YQ7A 4JWFA 1IPAA 4KDZA 4YPZA 4YQCA 4JWJA 1V2XA 4YQDA 4YQIA 4E8BA 4YQ5A 2I6DA 3IEFA 5GMCA 2QMMA 3OINA 4YQ8A 4MCCA 4YPWA 4YQTA 1UALA 4YQ0A 3DCMX 2V3KA 1OY5A 3GYQA 2NWAA 1VHKA 5GM8A 1P9PA 4CNEA 3IC6A 4H3YA 4CNDA 4YQ1A 3ILKA 1UAMA 4YQ9A 4YVGA 1UAKA 2V3JA 3QUVA 4RG1A 4YVIA 1ZJRA 2YY8A 4YQLA 2O3AA 3AI9X 3NK6A 2EGVA 3N4KA 4YQRA 3AIAA 1J85A 4IG6A 4YQ2A 4YQ6A 4XBOA 4CNFA 4L69A 1GZ0A 4YVHA 3KW2A 1V6ZA 4YPXA 5FAIA 4JWGA 4YQBA 4YQAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQN A;  4YQO A;  1O6D A;  2EGW A;  4CNG A;  1UAJ A;  4KGN A;  5GMB A;  4YQ3 A;  4YQG A;  3BBH A;  1VH0 A;  3NK7 A;  4YQJ A;  2QWV A;  3BBE A;  3BBD A;  1NS5 A;  3KTY A;  1X7P A;  2HA8 A;  3E5Y A;  3O7B A;  4MCD A;  3KY7 A;  4H3Z A;  4X3L A;  4FAK A;  4YVJ A;  5CO4 A;  4MCB A;  5D9F A;  4YQS A;  3KNU A;  4YQP A;  3AXZ A;  4PZK A;  4JAL A;  4YPY A;  1VHY A;  3OIJ A;  4YVK A;  1X7O A;  4YQQ A;  3N4J A;  3ONP A;  4JAK A;  1MXI A;  4YQK A;  1K3R A;  2CX8 A;  4J3C A;  4X3M A;  3L8U A;  2Z0Y A;  1Z85 A;  4YQ4 A;  1NXZ A;  1TO0 A;  3OII A;  4YQ7 A;  1IPA A;  4KDZ A;  4YPZ A;  4YQC A;  1V2X A;  4YQD A;  4YQI A;  4E8B A;  4YQ5 A;  2I6D A;  3IEF A;  5GMC A;  2QMM A;  3OIN A;  4YQ8 A;  4MCC A;  4YPW A;  4YQT A;  1UAL A;  4YQ0 A;  3DCM X;  2V3K A;  1OY5 A;  3GYQ A;  2NWA A;  1VHK A;  5GM8 A;  1P9P A;  4CNE A;  3IC6 A;  4H3Y A;  4CND A;  4YQ1 A;  3ILK A;  1UAM A;  4YQ9 A;  4YVG A;  1UAK A;  2V3J A;  3QUV A;  4RG1 A;  4YVI A;  1ZJR A;  2YY8 A;  4YQL A;  2O3A A;  3AI9 X;  3NK6 A;  2EGV A;  3N4K A;  4YQR A;  3AIA A;  1J85 A;  4IG6 A;  4YQ2 A;  4YQ6 A;  4XBO A;  4CNF A;  4L69 A;  1GZ0 A;  4YVH A;  3KW2 A;  1V6Z A;  4YPX A;  5FAI A;  4YQB A;  4YQA A; 
#chains in the Genus database with same CATH topology
 2GAE A;  2G5D A;  1EXD A;  4H4K A;  4YQN A;  4YQO A;  5GAG W;  1O6D A;  2EGW A;  4CNG A;  2ZJR S;  1UAJ A;  4KGN A;  5GMB A;  1EUY A;  4YQ3 A;  4YQG A;  4WFA S;  5JVG S;  3BBH A;  1VH0 A;  3NK7 A;  2HZ7 A;  4H3S A;  4YQJ A;  2QWV A;  4JWH A;  5GAD W;  2PIC A;  3BBE A;  3BBD A;  1NS5 A;  3KTY A;  1X7P A;  2HA8 A;  3E5Y A;  5IZN A;  3O7B A;  3KY7 A;  4H3Z A;  4MCD A;  4X3L A;  4FAK A;  1GTR A;  4YVJ A;  5CO4 A;  4MCB A;  3CF5 S;  4YQS A;  3AII A;  3KNU A;  5D9F A;  4YQP A;  3AXZ A;  4PZK A;  1GTS A;  2RD2 A;  4JAL A;  4YPY A;  1VHY A;  3OIJ A;  4YVK A;  1X7O A;  4FMW A;  2PI8 A;  4YQQ A;  3N4J A;  3ONP A;  4JAK A;  3J7Z V;  5DM7 S;  1MXI A;  4IO9 S;  2AE0 X;  2RE8 A;  4YQK A;  1K3R A;  2CX8 A;  4J3C A;  4X3M A;  2PJJ A;  2Z0Y A;  3L8U A;  4V19 4;  1QRU A;  1Z85 A;  3CZB A;  4YQ4 A;  1NXZ A;  1FEU A;  2ZJQ S;  3X1L B;  1TO0 A;  3OII A;  4YQ7 A;  4JWF A;  1IPA A;  4KDZ A;  1QTQ A;  4YPZ A;  5DM6 S;  4JXZ A;  5BNZ A;  4YQC A;  4JWJ A;  1V2X A;  4YQD A;  4YQI A;  4WCE S;  4E8B A;  4YQ5 A;  2I6D A;  3IEF A;  5GMC A;  5HL7 S;  2QMM A;  1NYL A;  3OIN A;  4YQ8 A;  4MCC A;  4YPW A;  4YQT A;  2PNW A;  1UAL A;  4YQ0 A;  3DCM X;  2V3K A;  1UDX A;  1OY5 A;  3GYQ A;  3PIO S;  1O0C A;  1B75 A;  2NWA A;  1DFU P;  4U67 S;  1VHK A;  5GM8 A;  1P9P A;  4CNE A;  4WF9 S;  3DLL S;  4JXX A;  3IC6 A;  4UY8 8;  4WFB S;  4H3Y A;  1D6K A;  4CND A;  4YQ1 A;  3ILK A;  5GAH W;  1UAM A;  4YQ9 A;  5JVH S;  4YVG A;  1UAK A;  1O0B A;  2V3J A;  3QUV A;  4RG1 A;  1QRT A;  4YVI A;  1ZJR A;  2YY8 A;  1ZJW A;  4YQL A;  1QRS A;  2O3A A;  3AI9 X;  4IOC S;  2EGV A;  2ZJP S;  3W2V B;  3N4K A;  3NK6 A;  4YQR A;  3AIA A;  1J85 A;  4IG6 A;  4YQ2 A;  4YQ6 A;  3W2W B;  4XBO A;  4CNF A;  4L69 A;  1GZ0 A;  4YVH A;  1V6Z A;  3KW2 A;  4WFN S;  4YPX A;  5FAI A;  4JYZ A;  2G6G A;  4IOA S;  4JWG A;  5GAE W;  1EUQ A;  4P2B A;  4YQB A;  4YQA A;  3PIP S; 
#chains in the Genus database with same CATH homology
 4YQN A;  4YQO A;  1O6D A;  2EGW A;  4CNG A;  1UAJ A;  4KGN A;  5GMB A;  4YQ3 A;  4YQG A;  3BBH A;  1VH0 A;  3NK7 A;  4YQJ A;  2QWV A;  4JWH A;  3BBE A;  3BBD A;  1NS5 A;  3KTY A;  1X7P A;  2HA8 A;  3E5Y A;  3O7B A;  4MCD A;  3KY7 A;  4H3Z A;  4X3L A;  4FAK A;  4YVJ A;  5CO4 A;  4MCB A;  5D9F A;  4YQS A;  3KNU A;  4YQP A;  3AXZ A;  4PZK A;  4JAL A;  4YPY A;  1VHY A;  3OIJ A;  4YVK A;  1X7O A;  4FMW A;  4YQQ A;  3N4J A;  3ONP A;  4JAK A;  1MXI A;  4YQK A;  1K3R A;  2CX8 A;  4J3C A;  4X3M A;  3L8U A;  2Z0Y A;  1Z85 A;  4YQ4 A;  1NXZ A;  1TO0 A;  3OII A;  4YQ7 A;  4JWF A;  1IPA A;  4KDZ A;  4YPZ A;  4YQC A;  4JWJ A;  1V2X A;  4YQD A;  4YQI A;  4E8B A;  4YQ5 A;  2I6D A;  3IEF A;  5GMC A;  2QMM A;  3OIN A;  4YQ8 A;  4MCC A;  4YPW A;  4YQT A;  1UAL A;  4YQ0 A;  3DCM X;  2V3K A;  1OY5 A;  3GYQ A;  2NWA A;  1VHK A;  5GM8 A;  1P9P A;  4CNE A;  3IC6 A;  4H3Y A;  4CND A;  4YQ1 A;  3ILK A;  1UAM A;  4YQ9 A;  4YVG A;  1UAK A;  2V3J A;  3QUV A;  4RG1 A;  4YVI A;  1ZJR A;  2YY8 A;  4YQL A;  2O3A A;  3AI9 X;  3NK6 A;  2EGV A;  3N4K A;  4YQR A;  3AIA A;  1J85 A;  4IG6 A;  4YQ2 A;  4YQ6 A;  4XBO A;  4CNF A;  4L69 A;  1GZ0 A;  4YVH A;  3KW2 A;  1V6Z A;  4YPX A;  5FAI A;  4JWG A;  4YQB A;  4YQA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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