4WFAS

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with linezolid
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S rRNA
total genus 18
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfaS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfaS02
1QTQA 1O0CA 1GTRA 5JVGS 1QRSA 4UY88 1DFUP 5GAEW 5IZNA 4JXXA 4IO9S 4U67S 2ZJPS 2RD2A 1FEUA 1QRTA 1O0BA 1NYLA 5GAHW 3CF5S 1B75A 1D6KA 4IOAS 4H3SA 1EUYA 4JYZA 3PIOS 4P2BA 4WFBS 4WFNS 3PIPS 1GTSA 4WF9S 1ZJWA 3J7ZV 5BNZA 4WFAS 5DM7S 3DLLS 1QRUA 2RE8A 3AIIA 4JXZA 2HZ7A 2ZJRS 5JVHS 5DM6S 4IOCS 5HL7S 5GADW 1EXDA 5GAGW 4WCES 2ZJQS 1EUQA
chains in the Genus database with same CATH superfamily
2PPBA 4LK0A 2Z0YA 5JVGS 3HOUC 2EGWA 4G7ZA 4G7OA 5IZNA 4JK1A 3GTQC 3S1QC 1BDFA 4JXXA 1Y1WC 4XSXA 5IYCC 2A6HA 5C4JC 1YNNA 4XLNA 1R9TC 1FEUA 4AYBD 2JA6C 2B63C 2VUMC 4IOAS 4MEXA 2Y0SD 1EUYA 2KXYA 2A68A 2NVQC 4A3EC 4WF9S 3PIPS 2NVTC 3HOWC 4OIPA 3I4NC 1TWFC 1ZJWA 2CX8A 4Q5SA 1YNJA 4LLGA 4XLPA 4C3HC 4G7HA 2A6EA 3K7AC 1V6ZA 1VHYA 3PO3C 1HQMA 4KMUA 3GTPC 3EQLA 4A3IC 4MEYA 2E2IC 2NVYC 4IOCS 4OIQA 3LYWA 2L5NA 5GAGW 4C3JC 4BY1C 3GTKC 2ZJQS 3I4MC 3PO2C 1EUQA 2O5JA 1O0CA 1I6HC 1QRSA 4UY88 3W2WB 1IW7A 2WB1D 2PJJA 4YFXA 3CQZC 4C2MC 3H0GC 3S2HC 4A3GC 2R7ZC 2JA8C 4ZH4A 4IO9S 2RD2A 1SFOC 3S1MC 1O0BA 5GAHW 3CF5S 1B75A 4OIOA 1NXZA 2PMZD 4X6AC 4JYZA 3PIOS 1GTSA 4YFKA 4A93C 5C4XC 1WCMC 2NWAA 2JA5C 2EGVA 5DM7S 3DLLS 2PA8D 4KN4A 4NOIA 4Y7NC 2NVXC 4A3CC 2G6GA 3KW2A 3HOYC 5JVHS 4BBSC 3HOZC 1K83C 5GADW 1EXDA 1TWHC 2KPUA 2G5DA 2GAEA 3CZBA 3GTOC 4A3JC 1Z85A 1TWCC 1GTRA 3HKZD 5IYDC 1DFUP 2JA7C 3S15C 3S1NC 2PNWA 4Q4ZA 4H4KA 5D4DA 3HOVC 4U67S 5IP7C 3S1RC 2ZJPS 2A69A 4MQ9A 4A3DC 4L69A 3W2VB 5FLMC 4P2BA 4WFBS 4WFNS 4GZYA 4BBRC 4A3MC 5TMCA 3J7ZV 1UDXA 2AE0X 4WFAS 5C3EC 2BE5A 3FKIC 3GTLC 3S2DC 4YG2A 3AIIA 4JXZA 2HZ7A 3GTJC 4LJZA 4V194 2ZJRS 4C3IC 4J3CA 1I3QC 1SMYA 4OINA 3M3YC 1QTQA 1VHKA 2CW0A 4A3FC 2PI8A 5GAEW 5TMFA 2PICA 4QJVA 2YU9C 3GTMC 4LK1A 3GTGC 3S17C 4BXXC 4E8BA 4OIRA 1ZYRA 1QRTA 1NYLA 4KN7A 4QIWD 1I50C 4XSZA 1D6KA 3WODA 4H3SA 3S16C 4A3KC 2R92C 3H3VD 3RZOC 1TWAC 5HQHA 2WAQD 5C44C 2E2JC 2O5IA 5BNZA 3RZDC 4BY7C 4Y52C 3S14C 2E2HC 5IP9C 1QRUA 2RE8A 3X1LB 1TWGC 2L3UA 5IYBC 2KQ1A 3M4OC 4YFNA 5DM6S 4A3BC 5HL7S 1Y1VC 3DXJA 4A3LC 2R93C 1I6VA 4WCES 3HOXC
chains in the Genus database with same CATH topology
1QTQA 1O0CA 1GTRA 5JVGS 1QRSA 4UY88 3W2WB 1DFUP 5GAEW 5IZNA 4H4KA 4JXXA 4IO9S 4U67S 2ZJPS 2RD2A 1FEUA 1QRTA 1O0BA 1NYLA 5GAHW 3CF5S 3W2VB 1D6KA 4IOAS 4H3SA 1B75A 1EUYA 4JYZA 4P2BA 4WFBS 3PIOS 4WFNS 3PIPS 1GTSA 4WF9S 1ZJWA 3J7ZV 5BNZA 1UDXA 4WFAS 5DM7S 3DLLS 1QRUA 2RE8A 3X1LB 3AIIA 4JXZA 2HZ7A 4V194 2ZJRS 5JVHS 5DM6S 4IOCS 5HL7S 5GADW 1EXDA 5GAGW 4WCES 2ZJQS 1EUQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QTQ A;  1O0C A;  1GTR A;  5JVG S;  1QRS A;  4UY8 8;  1DFU P;  5GAE W;  5IZN A;  4JXX A;  4IO9 S;  4U67 S;  2ZJP S;  2RD2 A;  1FEU A;  1QRT A;  1O0B A;  1NYL A;  5GAH W;  3CF5 S;  1B75 A;  1D6K A;  4IOA S;  4H3S A;  1EUY A;  4JYZ A;  3PIO S;  4P2B A;  4WFB S;  4WFN S;  3PIP S;  1GTS A;  4WF9 S;  1ZJW A;  3J7Z V;  5BNZ A;  4WFA S;  5DM7 S;  3DLL S;  1QRU A;  2RE8 A;  3AII A;  4JXZ A;  2HZ7 A;  2ZJR S;  5JVH S;  5DM6 S;  4IOC S;  5HL7 S;  5GAD W;  1EXD A;  5GAG W;  4WCE S;  2ZJQ S;  1EUQ A; 
#chains in the Genus database with same CATH topology
 2PPB A;  4LK0 A;  2Z0Y A;  5JVG S;  3HOU C;  2EGW A;  4G7Z A;  4G7O A;  5IZN A;  4JK1 A;  3GTQ C;  3S1Q C;  1BDF A;  4JXX A;  1Y1W C;  4XSX A;  5IYC C;  2A6H A;  5C4J C;  1YNN A;  4XLN A;  1R9T C;  1FEU A;  4AYB D;  2JA6 C;  2B63 C;  2VUM C;  4IOA S;  4MEX A;  2Y0S D;  1EUY A;  2KXY A;  2A68 A;  2NVQ C;  4A3E C;  4WF9 S;  3PIP S;  2NVT C;  3HOW C;  4OIP A;  3I4N C;  1TWF C;  1ZJW A;  2CX8 A;  4Q5S A;  1YNJ A;  4LLG A;  4XLP A;  4C3H C;  4G7H A;  2A6E A;  3K7A C;  1V6Z A;  1VHY A;  3PO3 C;  1HQM A;  4KMU A;  3GTP C;  3EQL A;  4A3I C;  4MEY A;  2E2I C;  2NVY C;  4IOC S;  4OIQ A;  3LYW A;  2L5N A;  5GAG W;  4C3J C;  4BY1 C;  3GTK C;  2ZJQ S;  3I4M C;  3PO2 C;  1EUQ A;  2O5J A;  1O0C A;  1I6H C;  1QRS A;  4UY8 8;  3W2W B;  1IW7 A;  2WB1 D;  2PJJ A;  4YFX A;  3CQZ C;  4C2M C;  3H0G C;  3S2H C;  4A3G C;  2R7Z C;  2JA8 C;  4ZH4 A;  4IO9 S;  2RD2 A;  1SFO C;  3S1M C;  1O0B A;  5GAH W;  3CF5 S;  1B75 A;  4OIO A;  1NXZ A;  2PMZ D;  4X6A C;  4JYZ A;  3PIO S;  1GTS A;  4YFK A;  4A93 C;  5C4X C;  1WCM C;  2NWA A;  2JA5 C;  2EGV A;  5DM7 S;  3DLL S;  2PA8 D;  4KN4 A;  4NOI A;  4Y7N C;  2NVX C;  4A3C C;  2G6G A;  3KW2 A;  3HOY C;  5JVH S;  4BBS C;  3HOZ C;  1K83 C;  5GAD W;  1EXD A;  1TWH C;  2KPU A;  2G5D A;  2GAE A;  3CZB A;  3GTO C;  4A3J C;  1Z85 A;  1TWC C;  1GTR A;  3HKZ D;  5IYD C;  1DFU P;  2JA7 C;  3S15 C;  3S1N C;  2PNW A;  4Q4Z A;  4H4K A;  5D4D A;  3HOV C;  4U67 S;  5IP7 C;  3S1R C;  2ZJP S;  2A69 A;  4MQ9 A;  4A3D C;  4L69 A;  3W2V B;  5FLM C;  4P2B A;  4WFB S;  4WFN S;  4GZY A;  4BBR C;  4A3M C;  5TMC A;  3J7Z V;  1UDX A;  2AE0 X;  4WFA S;  5C3E C;  2BE5 A;  3FKI C;  3GTL C;  3S2D C;  4YG2 A;  3AII A;  4JXZ A;  2HZ7 A;  3GTJ C;  4LJZ A;  4V19 4;  2ZJR S;  4C3I C;  4J3C A;  1I3Q C;  1SMY A;  4OIN A;  3M3Y C;  1QTQ A;  1VHK A;  2CW0 A;  4A3F C;  2PI8 A;  5GAE W;  5TMF A;  2PIC A;  4QJV A;  2YU9 C;  3GTM C;  4LK1 A;  3GTG C;  3S17 C;  4BXX C;  4E8B A;  4OIR A;  1ZYR A;  1QRT A;  1NYL A;  4KN7 A;  4QIW D;  1I50 C;  4XSZ A;  1D6K A;  3WOD A;  4H3S A;  3S16 C;  4A3K C;  2R92 C;  3H3V D;  3RZO C;  1TWA C;  5HQH A;  2WAQ D;  5C44 C;  2E2J C;  2O5I A;  5BNZ A;  3RZD C;  4BY7 C;  4Y52 C;  3S14 C;  2E2H C;  5IP9 C;  1QRU A;  2RE8 A;  3X1L B;  1TWG C;  2L3U A;  5IYB C;  2KQ1 A;  3M4O C;  4YFN A;  5DM6 S;  4A3B C;  5HL7 S;  1Y1V C;  3DXJ A;  4A3L C;  2R93 C;  1I6V A;  4WCE S;  3HOX C; 
#chains in the Genus database with same CATH homology
 1QTQ A;  1O0C A;  1GTR A;  5JVG S;  1QRS A;  4UY8 8;  3W2W B;  1DFU P;  5GAE W;  5IZN A;  4H4K A;  4JXX A;  4IO9 S;  4U67 S;  2ZJP S;  2RD2 A;  1FEU A;  1QRT A;  1O0B A;  1NYL A;  5GAH W;  3CF5 S;  3W2V B;  1D6K A;  4IOA S;  4H3S A;  1B75 A;  1EUY A;  4JYZ A;  4P2B A;  4WFB S;  3PIO S;  4WFN S;  3PIP S;  1GTS A;  4WF9 S;  1ZJW A;  3J7Z V;  5BNZ A;  1UDX A;  4WFA S;  5DM7 S;  3DLL S;  1QRU A;  2RE8 A;  3X1L B;  3AII A;  4JXZ A;  2HZ7 A;  4V19 4;  2ZJR S;  5JVH S;  5DM6 S;  4IOC S;  5HL7 S;  5GAD W;  1EXD A;  5GAG W;  4WCE S;  2ZJQ S;  1EUQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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