4WFAS

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with linezolid
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S rRNA
total genus 18
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfaS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfaS02
1QRSA 2ZJQS 1EUQA 1EUYA 4H3SA 4WFAS 4WFBS 3CF5S 3AIIA 4WFNS 1ZJWA 1QRUA 1GTSA 5GAHW 1O0BA 3J7ZV 5IZNA 5JVHS 1NYLA 5DM7S 3PIPS 1DFUP 5GADW 5DM6S 1FEUA 1EXDA 3PIOS 2RD2A 4IO9S 2ZJPS 4P2BA 2HZ7A 1QTQA 1QRTA 1B75A 3DLLS 5HL7S 2ZJRS 4JYZA 4IOAS 1D6KA 5JVGS 2RE8A 4WF9S 5GAGW 1O0CA 4UY88 4JXZA 1GTRA 5BNZA 4JXXA 4U67S 4IOCS 5GAEW 4WCES
chains in the Genus database with same CATH superfamily
4XLNA 2EGVA 4MQ9A 4QIWD 4WFAS 1R9TC 3W2WB 2O5IA 3RZOC 4LJZA 2EGWA 5D4DA 5GAHW 5IZNA 2E2JC 3S15C 5DM7S 4KN4A 1Z85A 1I6HC 4ZH4A 3RZDC 2RD2A 3PO2C 4BBRC 2R7ZC 5HQHA 1UDXA 3HOXC 3DXJA 2WAQD 2HZ7A 4BBSC 3GTPC 3S1MC 1Y1WC 1QRTA 1IW7A 2E2HC 2NVXC 3S1QC 2O5JA 5C4XC 1B75A 2ZJRS 3W2VB 2A6EA 2A6HA 4C3HC 3HOUC 4A3CC 4Q4ZA 1D6KA 2PNWA 4WF9S 2CW0A 5GAGW 4A3FC 4NOIA 3S2HC 1O0CA 3HOZC 5BNZA 4JXXA 4U67S 4WCES 4XSZA 1TWGC 2PPBA 2A69A 1QRSA 2AE0X 4X6AC 3CF5S 1V6ZA 1YNJA 3GTOC 2JA5C 4BXXC 4A3GC 3HKZD 4V194 3HOVC 4J3CA 2JA7C 3CZBA 2A68A 1NYLA 4OINA 3HOWC 5DM6S 4LK0A 1VHKA 4IO9S 4A3MC 5TMFA 4A3DC 4C3IC 2JA8C 3HOYC 3M4OC 3KW2A 4C2MC 2KXYA 2R93C 1I50C 4Y52C 4BY1C 3S17C 4IOAS 1NXZA 2Z0YA 5C44C 1Y1VC 3S1RC 2KQ1A 2WB1D 4KN7A 1K83C 4IOCS 4GZYA 4L69A 4Y7NC 3GTKC 1HQMA 5TMCA 2R92C 4OIQA 1EUQA 4WFBS 3AIIA 1ZJWA 3GTQC 5IP7C 2NWAA 2NVYC 3GTJC 3S1NC 2L5NA 3J7ZV 5JVHS 2PJJA 2NVTC 4AYBD 4E8BA 1WCMC 3PIPS 1DFUP 5GADW 2PI8A 1TWCC 1EXDA 3PIOS 1BDFA 1TWFC 1SFOC 1QTQA 2KPUA 4OIOA 2G5DA 2Y0SD 5IYCC 3DLLS 4JYZA 4YG2A 5IP9C 5FLMC 4C3JC 5JVGS 4JK1A 4UY88 4XLPA 4BY7C 1I3QC 3EQLA 2ZJQS 2RE8A 5GAEW 3FKIC 4KMUA 4A3BC 2BE5A 4A93C 4Q5SA 1EUYA 4H3SA 4QJVA 1VHYA 4XSXA 5IYBC 4WFNS 2PMZD 3M3YC 1QRUA 3S2DC 4A3LC 2B63C 1GTSA 2PICA 4YFKA 3PO3C 1O0BA 3S14C 2CX8A 3GTMC 3GTLC 1I6VA 4G7OA 4A3KC 3H3VD 3I4NC 1TWAC 1FEUA 4G7HA 2VUMC 3K7AC 2ZJPS 4LLGA 3X1LB 4P2BA 4A3EC 3GTGC 4G7ZA 2L3UA 4OIPA 3H0GC 5IYDC 4A3IC 3S16C 3WODA 4A3JC 2E2IC 4MEYA 2NVQC 1YNNA 5HL7S 3I4MC 4H4KA 2PA8D 1ZYRA 2G6GA 3LYWA 5C3EC 2JA6C 2GAEA 4MEXA 3CQZC 4OIRA 4LK1A 4JXZA 1GTRA 4YFXA 4YFNA 1SMYA 1TWHC 2YU9C 5C4JC
chains in the Genus database with same CATH topology
1QRSA 2ZJQS 1EUQA 1EUYA 4H3SA 4WFAS 3W2WB 4WFBS 3CF5S 3AIIA 4WFNS 1ZJWA 1QRUA 1GTSA 4V194 5GAHW 1O0BA 5IZNA 3J7ZV 5JVHS 1NYLA 5DM7S 3PIPS 1DFUP 5GADW 5DM6S 1FEUA 1EXDA 3PIOS 2RD2A 4IO9S 2ZJPS 1UDXA 3X1LB 4P2BA 2HZ7A 1QTQA 1QRTA 1B75A 3DLLS 5HL7S 3W2VB 2ZJRS 4H4KA 4JYZA 4IOAS 1D6KA 5JVGS 2RE8A 4WF9S 5GAGW 1O0CA 4UY88 4JXZA 1GTRA 5BNZA 4JXXA 4U67S 4IOCS 5GAEW 4WCES
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QRS A;  2ZJQ S;  1EUQ A;  1EUY A;  4H3S A;  4WFA S;  4WFB S;  3CF5 S;  3AII A;  4WFN S;  1ZJW A;  1QRU A;  1GTS A;  5GAH W;  1O0B A;  3J7Z V;  5IZN A;  5JVH S;  1NYL A;  5DM7 S;  3PIP S;  1DFU P;  5GAD W;  5DM6 S;  1FEU A;  1EXD A;  3PIO S;  2RD2 A;  4IO9 S;  2ZJP S;  4P2B A;  2HZ7 A;  1QTQ A;  1QRT A;  1B75 A;  3DLL S;  5HL7 S;  2ZJR S;  4JYZ A;  4IOA S;  1D6K A;  5JVG S;  2RE8 A;  4WF9 S;  5GAG W;  1O0C A;  4UY8 8;  4JXZ A;  1GTR A;  5BNZ A;  4JXX A;  4U67 S;  4IOC S;  5GAE W;  4WCE S; 
#chains in the Genus database with same CATH topology
 4XLN A;  2EGV A;  4MQ9 A;  4QIW D;  4WFA S;  1R9T C;  3W2W B;  2O5I A;  3RZO C;  4LJZ A;  2EGW A;  5D4D A;  5GAH W;  5IZN A;  2E2J C;  3S15 C;  5DM7 S;  4KN4 A;  1Z85 A;  1I6H C;  4ZH4 A;  3RZD C;  2RD2 A;  3PO2 C;  4BBR C;  2R7Z C;  5HQH A;  1UDX A;  3HOX C;  3DXJ A;  2WAQ D;  2HZ7 A;  4BBS C;  3GTP C;  3S1M C;  1Y1W C;  1QRT A;  1IW7 A;  2E2H C;  2NVX C;  3S1Q C;  2O5J A;  5C4X C;  1B75 A;  2ZJR S;  3W2V B;  2A6E A;  2A6H A;  4C3H C;  3HOU C;  4A3C C;  4Q4Z A;  1D6K A;  2PNW A;  4WF9 S;  2CW0 A;  5GAG W;  4A3F C;  4NOI A;  3S2H C;  1O0C A;  3HOZ C;  5BNZ A;  4JXX A;  4U67 S;  4WCE S;  4XSZ A;  1TWG C;  2PPB A;  2A69 A;  1QRS A;  2AE0 X;  4X6A C;  3CF5 S;  1V6Z A;  1YNJ A;  3GTO C;  2JA5 C;  4BXX C;  4A3G C;  3HKZ D;  4V19 4;  3HOV C;  4J3C A;  2JA7 C;  3CZB A;  2A68 A;  1NYL A;  4OIN A;  3HOW C;  5DM6 S;  4LK0 A;  1VHK A;  4IO9 S;  4A3M C;  5TMF A;  4A3D C;  4C3I C;  2JA8 C;  3HOY C;  3M4O C;  3KW2 A;  4C2M C;  2KXY A;  2R93 C;  1I50 C;  4Y52 C;  4BY1 C;  3S17 C;  4IOA S;  1NXZ A;  2Z0Y A;  5C44 C;  1Y1V C;  3S1R C;  2KQ1 A;  2WB1 D;  4KN7 A;  1K83 C;  4IOC S;  4GZY A;  4L69 A;  4Y7N C;  3GTK C;  1HQM A;  5TMC A;  2R92 C;  4OIQ A;  1EUQ A;  4WFB S;  3AII A;  1ZJW A;  3GTQ C;  5IP7 C;  2NWA A;  2NVY C;  3GTJ C;  3S1N C;  2L5N A;  3J7Z V;  5JVH S;  2PJJ A;  2NVT C;  4AYB D;  4E8B A;  1WCM C;  3PIP S;  1DFU P;  5GAD W;  2PI8 A;  1TWC C;  1EXD A;  3PIO S;  1BDF A;  1TWF C;  1SFO C;  1QTQ A;  2KPU A;  4OIO A;  2G5D A;  2Y0S D;  5IYC C;  3DLL S;  4JYZ A;  4YG2 A;  5IP9 C;  5FLM C;  4C3J C;  5JVG S;  4JK1 A;  4UY8 8;  4XLP A;  4BY7 C;  1I3Q C;  3EQL A;  2ZJQ S;  2RE8 A;  5GAE W;  3FKI C;  4KMU A;  4A3B C;  2BE5 A;  4A93 C;  4Q5S A;  1EUY A;  4H3S A;  4QJV A;  1VHY A;  4XSX A;  5IYB C;  4WFN S;  2PMZ D;  3M3Y C;  1QRU A;  3S2D C;  4A3L C;  2B63 C;  1GTS A;  2PIC A;  4YFK A;  3PO3 C;  1O0B A;  3S14 C;  2CX8 A;  3GTM C;  3GTL C;  1I6V A;  4G7O A;  4A3K C;  3H3V D;  3I4N C;  1TWA C;  1FEU A;  4G7H A;  2VUM C;  3K7A C;  2ZJP S;  4LLG A;  3X1L B;  4P2B A;  4A3E C;  3GTG C;  4G7Z A;  2L3U A;  4OIP A;  3H0G C;  5IYD C;  4A3I C;  3S16 C;  3WOD A;  4A3J C;  2E2I C;  4MEY A;  2NVQ C;  1YNN A;  5HL7 S;  3I4M C;  4H4K A;  2PA8 D;  1ZYR A;  2G6G A;  3LYW A;  5C3E C;  2JA6 C;  2GAE A;  4MEX A;  3CQZ C;  4OIR A;  4LK1 A;  4JXZ A;  1GTR A;  4YFX A;  4YFN A;  1SMY A;  1TWH C;  2YU9 C;  5C4J C; 
#chains in the Genus database with same CATH homology
 1QRS A;  2ZJQ S;  1EUQ A;  1EUY A;  4H3S A;  4WFA S;  3W2W B;  4WFB S;  3CF5 S;  3AII A;  4WFN S;  1ZJW A;  1QRU A;  1GTS A;  4V19 4;  5GAH W;  1O0B A;  5IZN A;  3J7Z V;  5JVH S;  1NYL A;  5DM7 S;  3PIP S;  1DFU P;  5GAD W;  5DM6 S;  1FEU A;  1EXD A;  3PIO S;  2RD2 A;  4IO9 S;  2ZJP S;  1UDX A;  3X1L B;  4P2B A;  2HZ7 A;  1QTQ A;  1QRT A;  1B75 A;  3DLL S;  5HL7 S;  3W2V B;  2ZJR S;  4H4K A;  4JYZ A;  4IOA S;  1D6K A;  5JVG S;  2RE8 A;  4WF9 S;  5GAG W;  1O0C A;  4UY8 8;  4JXZ A;  1GTR A;  5BNZ A;  4JXX A;  4U67 S;  4IOC S;  5GAE W;  4WCE S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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