4WFAS

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with linezolid
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
167
structure length
167
Chain Sequence
b'SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 23S rRNA
publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
total genus 18
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfaS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfaS02
4UY88 4IOAS 3J7ZV 2ZJPS 5HL7S 5DM7S 4JYZA 3AIIA 4WCES 1QRUA 5DM6S 4WF9S 1EUQA 4P2BA 2RD2A 4IOCS 5GAGW 1DFUP 5GAHW 5JVGS 2RE8A 4U67S 1GTSA 4H3SA 4IO9S 1NYLA 1EXDA 3DLLS 2ZJQS 5BNZA 3CF5S 4JXZA 4WFBS 5GADW 1QRTA 1O0CA 4WFAS 1D6KA 5JVHS 1O0BA 5IZNA 1QTQA 3PIPS 5GAEW 1ZJWA 1B75A 1GTRA 2HZ7A 3PIOS 1FEUA 4WFNS 2ZJRS 4JXXA 1QRSA 1EUYA
chains in the Genus database with same CATH superfamily
4BBSC 5IP7C 4UY88 1BDFA 2ZJPS 5HL7S 2EGWA 1QRUA 3GTPC 4A3BC 3K7AC 4WF9S 3S1MC 2AE0X 2RD2A 1DFUP 2PJJA 2CX8A 3WODA 4U67S 3LYWA 4MEYA 1V6ZA 4H3SA 1ZYRA 5D4DA 2R7ZC 1NYLA 2KXYA 3DXJA 3HKZD 1EXDA 1TWAC 1HQMA 3DLLS 1TWFC 3FKIC 4OIPA 4C2MC 1Y1WC 1Z85A 4WFBS 4G7OA 5C3EC 1WCMC 4A3JC 4MEXA 1SMYA 5JVHS 1QTQA 3PIPS 1GTRA 2B63C 5HQHA 3S1RC 3GTJC 4J3CA 1VHKA 5IYCC 4Y7NC 4E8BA 2A68A 4L69A 3H0GC 2EGVA 4A3MC 2R93C 3HOZC 4XLNA 4LK0A 4G7ZA 3J7ZV 2L5NA 3X1LB 5DM7S 2PPBA 4A3GC 1Y1VC 4Q5SA 5DM6S 4X6AC 2NVYC 3CQZC 5GAGW 3GTQC 2O5IA 4BY1C 3S1NC 4A3IC 4OIQA 2PNWA 2PI8A 2WAQD 4OIOA 1UDXA 4YFNA 5BNZA 4H4KA 3EQLA 2R92C 5TMCA 4A3FC 4A3LC 3S16C 4A3DC 5FLMC 3W2WB 5IYBC 5IYDC 2BE5A 3GTKC 3I4NC 3RZDC 1IW7A 2ZJRS 4JXXA 4LJZA 3HOUC 5C44C 2NWAA 1EUYA 2G6GA 4BY7C 4BBRC 3GTGC 3S2HC 3S2DC 1R9TC 2Y0SD 1TWHC 2JA6C 4WCES 2E2IC 4A93C 1EUQA 1I3QC 4C3IC 2Z0YA 2NVXC 3GTLC 4IOCS 4XLPA 1I50C 5GAHW 1SFOC 4JK1A 3W2VB 5IP9C 2RE8A 2CW0A 2WB1D 3KW2A 4IO9S 4NOIA 4C3JC 4G7HA 3HOVC 4C3HC 2O5JA 4MQ9A 1I6VA 3M3YC 4OIRA 4JXZA 4BXXC 5TMFA 3CZBA 1K83C 4WFAS 5C4XC 1YNNA 3S1QC 4XSZA 1NXZA 1O0BA 4KN7A 5IZNA 2E2HC 4KN4A 2PMZD 1ZJWA 1YNJA 2A6EA 2L3UA 4AYBD 4Y52C 4ZH4A 2KQ1A 2HZ7A 5C4JC 4YFKA 2YU9C 3S14C 4WFNS 4XSXA 2PICA 3RZOC 2KPUA 2E2JC 2JA5C 4IOAS 4QIWD 4JYZA 2JA7C 4YG2A 4KMUA 3AIIA 2PA8D 4P2BA 2A6HA 3PO3C 1I6HC 1VHYA 2A69A 2NVTC 1TWCC 3GTOC 3S15C 4GZYA 5JVGS 2NVQC 1TWGC 1GTSA 2VUMC 4A3CC 4QJVA 4YFXA 2ZJQS 3HOXC 3CF5S 4LLGA 5GADW 1QRTA 1O0CA 3H3VD 3I4MC 4OINA 4V194 2GAEA 3M4OC 1D6KA 4A3EC 3HOWC 4A3KC 5GAEW 3S17C 1B75A 2JA8C 3PIOS 1FEUA 3GTMC 2G5DA 4Q4ZA 1QRSA 3PO2C 3HOYC 4LK1A
chains in the Genus database with same CATH topology
4UY88 4IOAS 3J7ZV 2ZJPS 5HL7S 5DM7S 4JYZA 3AIIA 4WCES 1QRUA 5DM6S 3X1LB 4WF9S 1EUQA 4P2BA 2RD2A 4IOCS 5GAGW 1DFUP 5GAHW 3W2VB 5JVGS 2RE8A 4U67S 1GTSA 4H3SA 4IO9S 1NYLA 1EXDA 1UDXA 3DLLS 5BNZA 2ZJQS 4H4KA 3CF5S 4JXZA 4WFBS 5GADW 1QRTA 1O0CA 4WFAS 4V194 3W2WB 1D6KA 5JVHS 1O0BA 5IZNA 1QTQA 3PIPS 5GAEW 1ZJWA 1B75A 1GTRA 2HZ7A 3PIOS 1FEUA 4WFNS 2ZJRS 4JXXA 1QRSA 1EUYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UY8 8;  4IOA S;  3J7Z V;  2ZJP S;  5HL7 S;  5DM7 S;  4JYZ A;  3AII A;  4WCE S;  1QRU A;  5DM6 S;  4WF9 S;  1EUQ A;  4P2B A;  2RD2 A;  4IOC S;  5GAG W;  1DFU P;  5GAH W;  5JVG S;  2RE8 A;  4U67 S;  1GTS A;  4H3S A;  4IO9 S;  1NYL A;  1EXD A;  3DLL S;  2ZJQ S;  5BNZ A;  3CF5 S;  4JXZ A;  4WFB S;  5GAD W;  1QRT A;  1O0C A;  4WFA S;  1D6K A;  5JVH S;  1O0B A;  5IZN A;  1QTQ A;  3PIP S;  5GAE W;  1ZJW A;  1B75 A;  1GTR A;  2HZ7 A;  3PIO S;  1FEU A;  4WFN S;  2ZJR S;  4JXX A;  1QRS A;  1EUY A; 
#chains in the Genus database with same CATH topology
 4BBS C;  5IP7 C;  4UY8 8;  1BDF A;  2ZJP S;  5HL7 S;  2EGW A;  1QRU A;  3GTP C;  4A3B C;  3K7A C;  4WF9 S;  3S1M C;  2AE0 X;  2RD2 A;  1DFU P;  2PJJ A;  2CX8 A;  3WOD A;  4U67 S;  3LYW A;  4MEY A;  1V6Z A;  4H3S A;  1ZYR A;  5D4D A;  2R7Z C;  1NYL A;  2KXY A;  3DXJ A;  3HKZ D;  1EXD A;  1TWA C;  1HQM A;  3DLL S;  1TWF C;  3FKI C;  4OIP A;  4C2M C;  1Y1W C;  1Z85 A;  4WFB S;  4G7O A;  5C3E C;  1WCM C;  4A3J C;  4MEX A;  1SMY A;  5JVH S;  1QTQ A;  3PIP S;  1GTR A;  2B63 C;  5HQH A;  3S1R C;  3GTJ C;  4J3C A;  1VHK A;  5IYC C;  4Y7N C;  4E8B A;  2A68 A;  4L69 A;  3H0G C;  2EGV A;  4A3M C;  2R93 C;  3HOZ C;  4XLN A;  4LK0 A;  4G7Z A;  3J7Z V;  2L5N A;  3X1L B;  5DM7 S;  2PPB A;  4A3G C;  1Y1V C;  4Q5S A;  5DM6 S;  4X6A C;  2NVY C;  3CQZ C;  5GAG W;  3GTQ C;  2O5I A;  4BY1 C;  3S1N C;  4A3I C;  4OIQ A;  2PNW A;  2PI8 A;  2WAQ D;  4OIO A;  1UDX A;  4YFN A;  5BNZ A;  4H4K A;  3EQL A;  2R92 C;  5TMC A;  4A3F C;  4A3L C;  3S16 C;  4A3D C;  5FLM C;  3W2W B;  5IYB C;  5IYD C;  2BE5 A;  3GTK C;  3I4N C;  3RZD C;  1IW7 A;  2ZJR S;  4JXX A;  4LJZ A;  3HOU C;  5C44 C;  2NWA A;  1EUY A;  2G6G A;  4BY7 C;  4BBR C;  3GTG C;  3S2H C;  3S2D C;  1R9T C;  2Y0S D;  1TWH C;  2JA6 C;  4WCE S;  2E2I C;  4A93 C;  1EUQ A;  1I3Q C;  4C3I C;  2Z0Y A;  2NVX C;  3GTL C;  4IOC S;  4XLP A;  1I50 C;  5GAH W;  1SFO C;  4JK1 A;  3W2V B;  5IP9 C;  2RE8 A;  2CW0 A;  2WB1 D;  3KW2 A;  4IO9 S;  4NOI A;  4C3J C;  4G7H A;  3HOV C;  4C3H C;  2O5J A;  4MQ9 A;  1I6V A;  3M3Y C;  4OIR A;  4JXZ A;  4BXX C;  5TMF A;  3CZB A;  1K83 C;  4WFA S;  5C4X C;  1YNN A;  3S1Q C;  4XSZ A;  1NXZ A;  1O0B A;  4KN7 A;  5IZN A;  2E2H C;  4KN4 A;  2PMZ D;  1ZJW A;  1YNJ A;  2A6E A;  2L3U A;  4AYB D;  4Y52 C;  4ZH4 A;  2KQ1 A;  2HZ7 A;  5C4J C;  4YFK A;  2YU9 C;  3S14 C;  4WFN S;  4XSX A;  2PIC A;  3RZO C;  2KPU A;  2E2J C;  2JA5 C;  4IOA S;  4QIW D;  4JYZ A;  2JA7 C;  4YG2 A;  4KMU A;  3AII A;  2PA8 D;  4P2B A;  2A6H A;  3PO3 C;  1I6H C;  1VHY A;  2A69 A;  2NVT C;  1TWC C;  3GTO C;  3S15 C;  4GZY A;  5JVG S;  2NVQ C;  1TWG C;  1GTS A;  2VUM C;  4A3C C;  4QJV A;  4YFX A;  2ZJQ S;  3HOX C;  3CF5 S;  4LLG A;  5GAD W;  1QRT A;  1O0C A;  3H3V D;  3I4M C;  4OIN A;  4V19 4;  2GAE A;  3M4O C;  1D6K A;  4A3E C;  3HOW C;  4A3K C;  5GAE W;  3S17 C;  1B75 A;  2JA8 C;  3PIO S;  1FEU A;  3GTM C;  2G5D A;  4Q4Z A;  1QRS A;  3PO2 C;  3HOY C;  4LK1 A; 
#chains in the Genus database with same CATH homology
 4UY8 8;  4IOA S;  3J7Z V;  2ZJP S;  5HL7 S;  5DM7 S;  4JYZ A;  3AII A;  4WCE S;  1QRU A;  5DM6 S;  3X1L B;  4WF9 S;  1EUQ A;  4P2B A;  2RD2 A;  4IOC S;  5GAG W;  1DFU P;  5GAH W;  3W2V B;  5JVG S;  2RE8 A;  4U67 S;  1GTS A;  4H3S A;  4IO9 S;  1NYL A;  1EXD A;  1UDX A;  3DLL S;  5BNZ A;  2ZJQ S;  4H4K A;  3CF5 S;  4JXZ A;  4WFB S;  5GAD W;  1QRT A;  1O0C A;  4WFA S;  4V19 4;  3W2W B;  1D6K A;  5JVH S;  1O0B A;  5IZN A;  1QTQ A;  3PIP S;  5GAE W;  1ZJW A;  1B75 A;  1GTR A;  2HZ7 A;  3PIO S;  1FEU A;  4WFN S;  2ZJR S;  4JXX A;  1QRS A;  1EUY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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