4WFAS

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with linezolid
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
molecule keywords 23S rRNA
publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
total genus 18
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfaS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfaS02
2ZJPS 2RE8A 1QRTA 4P2BA 5GAEW 4H3SA 4IO9S 1O0BA 2RD2A 2ZJRS 1EXDA 1O0CA 1FEUA 5HL7S 5DM6S 4WFAS 1NYLA 3AIIA 3J7ZV 1EUQA 4U67S 5GAGW 1B75A 4IOAS 3PIOS 1EUYA 4WCES 3DLLS 4WFNS 4JXXA 1QRUA 4WF9S 5BNZA 4JXZA 1QTQA 5JVHS 5IZNA 1ZJWA 4WFBS 5JVGS 1QRSA 4UY88 3PIPS 1GTRA 4JYZA 1GTSA 5DM7S 4IOCS 5GAHW 2HZ7A 1D6KA 1DFUP 2ZJQS 3CF5S 5GADW
chains in the Genus database with same CATH superfamily
3HOVC 2WAQD 2ZJPS 2YU9C 2Y0SD 3I4MC 2PICA 4H3SA 2NWAA 1K83C 4YFXA 1EXDA 4YFNA 4KN4A 1IW7A 4A3BC 5DM6S 2G5DA 4Q4ZA 2PPBA 4U67S 5GAGW 1B75A 4OIRA 4WCES 2BE5A 4QJVA 2E2HC 2PNWA 3KW2A 3DLLS 1BDFA 5IYCC 4WF9S 2A68A 4OIQA 5BNZA 4BBRC 4JXZA 3GTKC 1I6HC 3S15C 3GTMC 5IZNA 4KN7A 4A3CC 2E2JC 4OIOA 2A6HA 4G7OA 1NXZA 1GTSA 4J3CA 4YFKA 3RZDC 2ZJQS 2AE0X 1UDXA 2E2IC 3HOUC 3CQZC 4A93C 2L3UA 1Z85A 1TWGC 3S14C 2RE8A 1QRTA 5C3EC 2JA5C 4P2BA 2PA8D 5GAEW 2G6GA 2NVTC 4V194 1O0CA 1FEUA 5HQHA 1VHKA 1TWFC 2KQ1A 4A3JC 4A3FC 4Y52C 1YNJA 2Z0YA 1TWCC 4GZYA 4LLGA 4C2MC 4A3DC 4IOAS 3PIOS 5C4JC 3GTOC 2WB1D 5IP7C 4A3EC 2JA6C 3LYWA 2PI8A 1HQMA 1R9TC 3S1NC 4LJZA 5JVHS 5C44C 4WFBS 1YNNA 1QRSA 2KPUA 3H3VD 2O5IA 2PMZD 4YG2A 4H4KA 5FLMC 4JYZA 3S1MC 5GAHW 4XLNA 1VHYA 1D6KA 4E8BA 2R92C 4G7HA 3S17C 3S16C 1I3QC 2RD2A 3DXJA 2R7ZC 3X1LB 1I6VA 2L5NA 2A69A 4AYBD 5TMFA 3GTLC 4BBSC 4KMUA 4MEYA 3HOWC 3W2WB 5IYBC 2KXYA 4X6AC 5HL7S 2EGVA 3AIIA 3GTJC 3HOZC 1EUYA 4A3MC 1Y1VC 4WFNS 4Q5SA 4JXXA 3EQLA 3HKZD 3S1RC 3GTPC 1ZYRA 4LK1A 1SMYA 2NVQC 1QTQA 4ZH4A 1ZJWA 4C3IC 2NVXC 3I4NC 5JVGS 3HOXC 3CZBA 1TWHC 4QIWD 3M3YC 3PO2C 3PIPS 4BXXC 5DM7S 4IOCS 2HZ7A 2CW0A 4G7ZA 2R93C 4XSXA 3CF5S 3PO3C 4A3GC 1GTRA 5GADW 1WCMC 5D4DA 2JA7C 5IYDC 4A3IC 4L69A 4IO9S 4MEXA 1O0BA 4OIPA 2ZJRS 4NOIA 1SFOC 2JA8C 3GTQC 1NYLA 3W2VB 4WFAS 3J7ZV 1EUQA 4XLPA 4C3HC 4A3LC 4A3KC 2O5JA 1I50C 4C3JC 1QRUA 2NVYC 2EGWA 3FKIC 2CX8A 3K7AC 3RZOC 2B63C 3HOYC 4MQ9A 2GAEA 4JK1A 3WODA 1V6ZA 3H0GC 4XSZA 4UY88 5IP9C 3M4OC 5C4XC 3S1QC 2PJJA 4LK0A 3GTGC 4Y7NC 4BY1C 5TMCA 1TWAC 2VUMC 1DFUP 2A6EA 4OINA 3S2HC 1Y1WC 3S2DC 4BY7C
chains in the Genus database with same CATH topology
2ZJPS 2RE8A 1QRTA 3X1LB 4P2BA 5GAEW 4H3SA 4IO9S 1O0BA 2RD2A 2ZJRS 1EXDA 4V194 1O0CA 1FEUA 3W2WB 5HL7S 5DM6S 1NYLA 3W2VB 3AIIA 4WFAS 3J7ZV 4U67S 5GAGW 1EUQA 4IOAS 3PIOS 1EUYA 1B75A 4WCES 3DLLS 4WFNS 4JXXA 1QRUA 4WF9S 5BNZA 4JXZA 1QTQA 5JVHS 5IZNA 1ZJWA 4WFBS 5JVGS 1QRSA 4UY88 3PIPS 4H4KA 1GTRA 4JYZA 1GTSA 5DM7S 4IOCS 5GAHW 2HZ7A 1D6KA 1DFUP 2ZJQS 1UDXA 3CF5S 5GADW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJP S;  2RE8 A;  1QRT A;  4P2B A;  5GAE W;  4H3S A;  4IO9 S;  1O0B A;  2RD2 A;  2ZJR S;  1EXD A;  1O0C A;  1FEU A;  5HL7 S;  5DM6 S;  4WFA S;  1NYL A;  3AII A;  3J7Z V;  1EUQ A;  4U67 S;  5GAG W;  1B75 A;  4IOA S;  3PIO S;  1EUY A;  4WCE S;  3DLL S;  4WFN S;  4JXX A;  1QRU A;  4WF9 S;  5BNZ A;  4JXZ A;  1QTQ A;  5JVH S;  5IZN A;  1ZJW A;  4WFB S;  5JVG S;  1QRS A;  4UY8 8;  3PIP S;  1GTR A;  4JYZ A;  1GTS A;  5DM7 S;  4IOC S;  5GAH W;  2HZ7 A;  1D6K A;  1DFU P;  2ZJQ S;  3CF5 S;  5GAD W; 
#chains in the Genus database with same CATH topology
 3HOV C;  2WAQ D;  2ZJP S;  2YU9 C;  2Y0S D;  3I4M C;  2PIC A;  4H3S A;  2NWA A;  1K83 C;  4YFX A;  1EXD A;  4YFN A;  4KN4 A;  1IW7 A;  4A3B C;  5DM6 S;  2G5D A;  4Q4Z A;  2PPB A;  4U67 S;  5GAG W;  1B75 A;  4OIR A;  4WCE S;  2BE5 A;  4QJV A;  2E2H C;  2PNW A;  3KW2 A;  3DLL S;  1BDF A;  5IYC C;  4WF9 S;  2A68 A;  4OIQ A;  5BNZ A;  4BBR C;  4JXZ A;  3GTK C;  1I6H C;  3S15 C;  3GTM C;  5IZN A;  4KN7 A;  4A3C C;  2E2J C;  4OIO A;  2A6H A;  4G7O A;  1NXZ A;  1GTS A;  4J3C A;  4YFK A;  3RZD C;  2ZJQ S;  2AE0 X;  1UDX A;  2E2I C;  3HOU C;  3CQZ C;  4A93 C;  2L3U A;  1Z85 A;  1TWG C;  3S14 C;  2RE8 A;  1QRT A;  5C3E C;  2JA5 C;  4P2B A;  2PA8 D;  5GAE W;  2G6G A;  2NVT C;  4V19 4;  1O0C A;  1FEU A;  5HQH A;  1VHK A;  1TWF C;  2KQ1 A;  4A3J C;  4A3F C;  4Y52 C;  1YNJ A;  2Z0Y A;  1TWC C;  4GZY A;  4LLG A;  4C2M C;  4A3D C;  4IOA S;  3PIO S;  5C4J C;  3GTO C;  2WB1 D;  5IP7 C;  4A3E C;  2JA6 C;  3LYW A;  2PI8 A;  1HQM A;  1R9T C;  3S1N C;  4LJZ A;  5JVH S;  5C44 C;  4WFB S;  1YNN A;  1QRS A;  2KPU A;  3H3V D;  2O5I A;  2PMZ D;  4YG2 A;  4H4K A;  5FLM C;  4JYZ A;  3S1M C;  5GAH W;  4XLN A;  1VHY A;  1D6K A;  4E8B A;  2R92 C;  4G7H A;  3S17 C;  3S16 C;  1I3Q C;  2RD2 A;  3DXJ A;  2R7Z C;  3X1L B;  1I6V A;  2L5N A;  2A69 A;  4AYB D;  5TMF A;  3GTL C;  4BBS C;  4KMU A;  4MEY A;  3HOW C;  3W2W B;  5IYB C;  2KXY A;  4X6A C;  5HL7 S;  2EGV A;  3AII A;  3GTJ C;  3HOZ C;  1EUY A;  4A3M C;  1Y1V C;  4WFN S;  4Q5S A;  4JXX A;  3EQL A;  3HKZ D;  3S1R C;  3GTP C;  1ZYR A;  4LK1 A;  1SMY A;  2NVQ C;  1QTQ A;  4ZH4 A;  1ZJW A;  4C3I C;  2NVX C;  3I4N C;  5JVG S;  3HOX C;  3CZB A;  1TWH C;  4QIW D;  3M3Y C;  3PO2 C;  3PIP S;  4BXX C;  5DM7 S;  4IOC S;  2HZ7 A;  2CW0 A;  4G7Z A;  2R93 C;  4XSX A;  3CF5 S;  3PO3 C;  4A3G C;  1GTR A;  5GAD W;  1WCM C;  5D4D A;  2JA7 C;  5IYD C;  4A3I C;  4L69 A;  4IO9 S;  4MEX A;  1O0B A;  4OIP A;  2ZJR S;  4NOI A;  1SFO C;  2JA8 C;  3GTQ C;  1NYL A;  3W2V B;  4WFA S;  3J7Z V;  1EUQ A;  4XLP A;  4C3H C;  4A3L C;  4A3K C;  2O5J A;  1I50 C;  4C3J C;  1QRU A;  2NVY C;  2EGW A;  3FKI C;  2CX8 A;  3K7A C;  3RZO C;  2B63 C;  3HOY C;  4MQ9 A;  2GAE A;  4JK1 A;  3WOD A;  1V6Z A;  3H0G C;  4XSZ A;  4UY8 8;  5IP9 C;  3M4O C;  5C4X C;  3S1Q C;  2PJJ A;  4LK0 A;  3GTG C;  4Y7N C;  4BY1 C;  5TMC A;  1TWA C;  2VUM C;  1DFU P;  2A6E A;  4OIN A;  3S2H C;  1Y1W C;  3S2D C;  4BY7 C; 
#chains in the Genus database with same CATH homology
 2ZJP S;  2RE8 A;  1QRT A;  3X1L B;  4P2B A;  5GAE W;  4H3S A;  4IO9 S;  1O0B A;  2RD2 A;  2ZJR S;  1EXD A;  4V19 4;  1O0C A;  1FEU A;  3W2W B;  5HL7 S;  5DM6 S;  1NYL A;  3W2V B;  3AII A;  4WFA S;  3J7Z V;  4U67 S;  5GAG W;  1EUQ A;  4IOA S;  3PIO S;  1EUY A;  1B75 A;  4WCE S;  3DLL S;  4WFN S;  4JXX A;  1QRU A;  4WF9 S;  5BNZ A;  4JXZ A;  1QTQ A;  5JVH S;  5IZN A;  1ZJW A;  4WFB S;  5JVG S;  1QRS A;  4UY8 8;  3PIP S;  4H4K A;  1GTR A;  4JYZ A;  1GTS A;  5DM7 S;  4IOC S;  5GAH W;  2HZ7 A;  1D6K A;  1DFU P;  2ZJQ S;  1UDX A;  3CF5 S;  5GAD W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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