4WF9S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with telithromycin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 24
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wf9S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wf9S02
1EXDA 4WFBS 1QRUA 2ZJPS 4IOAS 4WF9S 2RE8A 5BNZA 5HL7S 4JYZA 4IO9S 2ZJQS 1O0CA 1D6KA 4JXXA 3PIPS 5DM6S 4U67S 2HZ7A 4JXZA 4P2BA 4WCES 1FEUA 5GADW 3PIOS 1NYLA 3DLLS 5IZNA 1QRTA 1EUQA 3AIIA 5JVGS 5DM7S 3CF5S 3J7ZV 2RD2A 2ZJRS 4H3SA 1O0BA 1EUYA 5GAGW 1QRSA 1DFUP 4UY88 5GAHW 4WFAS 1GTRA 1QTQA 1GTSA 5GAEW 4IOCS 1ZJWA 4WFNS 5JVHS 1B75A
chains in the Genus database with same CATH superfamily
3S1QC 1EXDA 1QRUA 3S1MC 3W2WB 2RE8A 2PA8D 2Y0SD 4LK0A 4IO9S 4OIQA 3GTQC 3HOZC 1O0CA 1TWFC 3LYWA 3PIPS 2AE0X 2PI8A 4A3MC 4J3CA 2R93C 3S17C 4ZH4A 4WCES 1FEUA 3HOVC 5GADW 1TWHC 1BDFA 2PMZD 2JA5C 1EUQA 4C3IC 3HOXC 3I4NC 4KMUA 2RD2A 1EUYA 4A3GC 1IW7A 5GAGW 2E2JC 4MQ9A 2A68A 2NVYC 1GTRA 4Q4ZA 1QTQA 3GTGC 4A3CC 2EGWA 4QJVA 5GAEW 1ZYRA 5TMCA 4C3JC 4C2MC 2R7ZC 3I4MC 5IP9C 2JA6C 2L3UA 1ZJWA 1UDXA 5TMFA 4WFBS 4XSZA 3HOYC 5FLMC 5HL7S 4OIOA 5C4JC 2G6GA 2KPUA 1D6KA 3GTLC 5DM6S 4QIWD 4Y52C 2O5JA 2E2HC 2HZ7A 3HOUC 4Q5SA 4JXZA 4Y7NC 4X6AC 1K83C 5IZNA 4A3EC 4A3KC 3FKIC 1SFOC 2PNWA 4XSXA 1WCMC 3AIIA 4BY7C 4BY1C 2JA8C 4YG2A 4L69A 1Z85A 4XLNA 3CQZC 2ZJRS 4G7ZA 1O0BA 4OINA 4A3BC 1NXZA 1QRSA 4LK1A 4YFNA 4MEXA 4UY88 3GTMC 4YFXA 3HKZD 4JK1A 2CW0A 3S1NC 3RZDC 3S15C 2Z0YA 4OIPA 5IYBC 4A3FC 1TWCC 4G7HA 5C4XC 4BXXC 3X1LB 1YNJA 2ZJPS 4WF9S 3S2DC 5BNZA 3DXJA 4MEYA 5C44C 1HQMA 3GTKC 2BE5A 1I3QC 4JXXA 5IYCC 4BBRC 2E2IC 3S2HC 4GZYA 2CX8A 1V6ZA 3RZOC 5HQHA 2JA7C 2A69A 3HOWC 1SMYA 3EQLA 1QRTA 2YU9C 4NOIA 4YFKA 4V194 4BBSC 2KXYA 3CZBA 2L5NA 2G5DA 5JVGS 2WB1D 3H0GC 3J7ZV 2NVQC 2WAQD 5IYDC 3M4OC 2KQ1A 3PO3C 5GAHW 2NVTC 3W2VB 4OIRA 2GAEA 2NVXC 1GTSA 3S16C 2B63C 4A3JC 3PO2C 2PJJA 3GTOC 4KN4A 2VUMC 1I50C 4WFNS 4IOCS 1NYLA 5JVHS 2O5IA 4IOAS 2A6HA 5C3EC 4KN7A 4A3IC 4JYZA 2PICA 3S1RC 1Y1WC 3KW2A 2ZJQS 1VHYA 3GTJC 4LJZA 3H3VD 4U67S 3GTPC 4A3DC 1I6HC 1YNNA 4P2BA 1Y1VC 4A93C 3PIOS 3DLLS 1TWAC 4H4KA 4G7OA 4E8BA 1R9TC 2A6EA 2PPBA 4A3LC 5DM7S 3CF5S 4AYBD 1VHKA 4H3SA 1TWGC 4LLGA 3S14C 2EGVA 1DFUP 5D4DA 3M3YC 4WFAS 2NWAA 2R92C 1I6VA 3WODA 3K7AC 4XLPA 5IP7C 1B75A 4C3HC
chains in the Genus database with same CATH topology
1EXDA 4WFBS 1QRUA 2ZJPS 4IOAS 3W2WB 2RE8A 4WF9S 5BNZA 5HL7S 4JYZA 4IO9S 2ZJQS 1O0CA 1D6KA 4JXXA 3PIPS 5DM6S 4U67S 2HZ7A 4JXZA 4P2BA 4WCES 1FEUA 5GADW 1NYLA 3PIOS 3DLLS 5IZNA 4H4KA 1QRTA 1EUQA 3AIIA 4V194 1ZJWA 5JVGS 5DM7S 3CF5S 3J7ZV 2RD2A 2ZJRS 4H3SA 1O0BA 1EUYA 5GAGW 1B75A 1QRSA 1DFUP 4UY88 5GAHW 4WFAS 1GTRA 1QTQA 3W2VB 1GTSA 5GAEW 4IOCS 1UDXA 4WFNS 5JVHS 3X1LB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EXD A;  4WFB S;  1QRU A;  2ZJP S;  4IOA S;  4WF9 S;  2RE8 A;  5BNZ A;  5HL7 S;  4JYZ A;  4IO9 S;  2ZJQ S;  1O0C A;  1D6K A;  4JXX A;  3PIP S;  5DM6 S;  4U67 S;  2HZ7 A;  4JXZ A;  4P2B A;  4WCE S;  1FEU A;  5GAD W;  3PIO S;  1NYL A;  3DLL S;  5IZN A;  1QRT A;  1EUQ A;  3AII A;  5JVG S;  5DM7 S;  3CF5 S;  3J7Z V;  2RD2 A;  2ZJR S;  4H3S A;  1O0B A;  1EUY A;  5GAG W;  1QRS A;  1DFU P;  4UY8 8;  5GAH W;  4WFA S;  1GTR A;  1QTQ A;  1GTS A;  5GAE W;  4IOC S;  1ZJW A;  4WFN S;  5JVH S;  1B75 A; 
#chains in the Genus database with same CATH topology
 3S1Q C;  1EXD A;  1QRU A;  3S1M C;  3W2W B;  2RE8 A;  2PA8 D;  2Y0S D;  4LK0 A;  4IO9 S;  4OIQ A;  3GTQ C;  3HOZ C;  1O0C A;  1TWF C;  3LYW A;  3PIP S;  2AE0 X;  2PI8 A;  4A3M C;  4J3C A;  2R93 C;  3S17 C;  4ZH4 A;  4WCE S;  1FEU A;  3HOV C;  5GAD W;  1TWH C;  1BDF A;  2PMZ D;  2JA5 C;  1EUQ A;  4C3I C;  3HOX C;  3I4N C;  4KMU A;  2RD2 A;  1EUY A;  4A3G C;  1IW7 A;  5GAG W;  2E2J C;  4MQ9 A;  2A68 A;  2NVY C;  1GTR A;  4Q4Z A;  1QTQ A;  3GTG C;  4A3C C;  2EGW A;  4QJV A;  5GAE W;  1ZYR A;  5TMC A;  4C3J C;  4C2M C;  2R7Z C;  3I4M C;  5IP9 C;  2JA6 C;  2L3U A;  1ZJW A;  1UDX A;  5TMF A;  4WFB S;  4XSZ A;  3HOY C;  5FLM C;  5HL7 S;  4OIO A;  5C4J C;  2G6G A;  2KPU A;  1D6K A;  3GTL C;  5DM6 S;  4QIW D;  4Y52 C;  2O5J A;  2E2H C;  2HZ7 A;  3HOU C;  4Q5S A;  4JXZ A;  4Y7N C;  4X6A C;  1K83 C;  5IZN A;  4A3E C;  4A3K C;  3FKI C;  1SFO C;  2PNW A;  4XSX A;  1WCM C;  3AII A;  4BY7 C;  4BY1 C;  2JA8 C;  4YG2 A;  4L69 A;  1Z85 A;  4XLN A;  3CQZ C;  2ZJR S;  4G7Z A;  1O0B A;  4OIN A;  4A3B C;  1NXZ A;  1QRS A;  4LK1 A;  4YFN A;  4MEX A;  4UY8 8;  3GTM C;  4YFX A;  3HKZ D;  4JK1 A;  2CW0 A;  3S1N C;  3RZD C;  3S15 C;  2Z0Y A;  4OIP A;  5IYB C;  4A3F C;  1TWC C;  4G7H A;  5C4X C;  4BXX C;  3X1L B;  1YNJ A;  2ZJP S;  4WF9 S;  3S2D C;  5BNZ A;  3DXJ A;  4MEY A;  5C44 C;  1HQM A;  3GTK C;  2BE5 A;  1I3Q C;  4JXX A;  5IYC C;  4BBR C;  2E2I C;  3S2H C;  4GZY A;  2CX8 A;  1V6Z A;  3RZO C;  5HQH A;  2JA7 C;  2A69 A;  3HOW C;  1SMY A;  3EQL A;  1QRT A;  2YU9 C;  4NOI A;  4YFK A;  4V19 4;  4BBS C;  2KXY A;  3CZB A;  2L5N A;  2G5D A;  5JVG S;  2WB1 D;  3H0G C;  3J7Z V;  2NVQ C;  2WAQ D;  5IYD C;  3M4O C;  2KQ1 A;  3PO3 C;  5GAH W;  2NVT C;  3W2V B;  4OIR A;  2GAE A;  2NVX C;  1GTS A;  3S16 C;  2B63 C;  4A3J C;  3PO2 C;  2PJJ A;  3GTO C;  4KN4 A;  2VUM C;  1I50 C;  4WFN S;  4IOC S;  1NYL A;  5JVH S;  2O5I A;  4IOA S;  2A6H A;  5C3E C;  4KN7 A;  4A3I C;  4JYZ A;  2PIC A;  3S1R C;  1Y1W C;  3KW2 A;  2ZJQ S;  1VHY A;  3GTJ C;  4LJZ A;  3H3V D;  4U67 S;  3GTP C;  4A3D C;  1I6H C;  1YNN A;  4P2B A;  1Y1V C;  4A93 C;  3PIO S;  3DLL S;  1TWA C;  4H4K A;  4G7O A;  4E8B A;  1R9T C;  2A6E A;  2PPB A;  4A3L C;  5DM7 S;  3CF5 S;  4AYB D;  1VHK A;  4H3S A;  1TWG C;  4LLG A;  3S14 C;  2EGV A;  1DFU P;  5D4D A;  3M3Y C;  4WFA S;  2NWA A;  2R92 C;  1I6V A;  3WOD A;  3K7A C;  4XLP A;  5IP7 C;  1B75 A;  4C3H C; 
#chains in the Genus database with same CATH homology
 1EXD A;  4WFB S;  1QRU A;  2ZJP S;  4IOA S;  3W2W B;  2RE8 A;  4WF9 S;  5BNZ A;  5HL7 S;  4JYZ A;  4IO9 S;  2ZJQ S;  1O0C A;  1D6K A;  4JXX A;  3PIP S;  5DM6 S;  4U67 S;  2HZ7 A;  4JXZ A;  4P2B A;  4WCE S;  1FEU A;  5GAD W;  1NYL A;  3PIO S;  3DLL S;  5IZN A;  4H4K A;  1QRT A;  1EUQ A;  3AII A;  4V19 4;  1ZJW A;  5JVG S;  5DM7 S;  3CF5 S;  3J7Z V;  2RD2 A;  2ZJR S;  4H3S A;  1O0B A;  1EUY A;  5GAG W;  1B75 A;  1QRS A;  1DFU P;  4UY8 8;  5GAH W;  4WFA S;  1GTR A;  1QTQ A;  3W2V B;  1GTS A;  5GAE W;  4IOC S;  1UDX A;  4WFN S;  5JVH S;  3X1L B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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