4WF9S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with telithromycin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
molecule keywords 23S ribosomal RNA
publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
total genus 24
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wf9S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wf9S02
4WFBS 4WFAS 1QRTA 1QTQA 4WCES 5GADW 5HL7S 1O0CA 4P2BA 1EXDA 4WF9S 1GTRA 2ZJPS 4JYZA 3CF5S 4JXXA 3AIIA 5GAGW 1ZJWA 1EUQA 1QRUA 5JVGS 4IOAS 4IOCS 2RE8A 1EUYA 2HZ7A 1O0BA 1FEUA 5GAEW 2ZJQS 2RD2A 5DM7S 1DFUP 1QRSA 5BNZA 5DM6S 5JVHS 4H3SA 1NYLA 3PIPS 3DLLS 1B75A 1D6KA 4UY88 1GTSA 5GAHW 4IO9S 5IZNA 4WFNS 3PIOS 4JXZA 2ZJRS 4U67S 3J7ZV
chains in the Genus database with same CATH superfamily
2JA5C 4XSZA 2CX8A 4WFAS 2VUMC 3DXJA 3I4MC 3S1NC 4WCES 3K7AC 4XLPA 3CZBA 1TWHC 2G5DA 1IW7A 2KQ1A 3KW2A 5IYBC 4JYZA 2A69A 5GAGW 1ZJWA 4OIQA 5JVGS 4LLGA 5FLMC 2KPUA 4C3JC 4G7HA 3S1RC 4IOCS 2JA8C 4BY7C 2HZ7A 1O0BA 1K83C 1I6HC 5IYDC 2ZJQS 4QIWD 2O5IA 2RD2A 4AYBD 2NWAA 2A6EA 4H3SA 4BBSC 1SMYA 5IYCC 4XLNA 4A3IC 3HOUC 5GAHW 3S2DC 3S1MC 4YFNA 5IZNA 2PPBA 3PO3C 2ZJRS 1TWGC 4XSXA 5TMCA 1TWCC 3H3VD 3X1LB 4H4KA 1TWAC 2Y0SD 1I6VA 1Y1WC 2WAQD 4Y7NC 3EQLA 4X6AC 1GTRA 3LYWA 4A3BC 4LK1A 3GTPC 1HQMA 4YFXA 1QRUA 4BXXC 1VHYA 2EGVA 3CQZC 3GTGC 2AE0X 2PA8D 3HOVC 2NVQC 4OIPA 2GAEA 4G7ZA 1VHKA 2A6HA 5DM7S 4E8BA 1QRSA 4KN7A 4JK1A 4A93C 1NYLA 3I4NC 3DLLS 1B75A 1D6KA 1WCMC 5HQHA 4U67S 1TWFC 5C4JC 4Q4ZA 2E2IC 3HOWC 4V194 3FKIC 4WFNS 2PMZD 4L69A 4JXZA 1Z85A 2JA7C 3W2WB 2EGWA 3J7ZV 3HKZD 4WFBS 4QJVA 3HOXC 1SFOC 2R7ZC 1QTQA 3W2VB 3M3YC 5HL7S 2CW0A 1EXDA 4YFKA 4WF9S 3GTMC 2ZJPS 2O5JA 3CF5S 3AIIA 4C3IC 4C3HC 4OIOA 4IOAS 2RE8A 5C3EC 1ZYRA 4A3MC 5GAEW 4MEXA 2NVTC 3S16C 4A3JC 2PICA 1DFUP 2PI8A 4LK0A 3PO2C 3GTOC 3S15C 1V6ZA 5DM6S 4A3GC 1I50C 3GTQC 3S14C 3M4OC 3PIPS 2WB1D 5D4DA 4A3FC 2E2JC 4A3LC 4Q5SA 4MEYA 1GTSA 2L3UA 1YNNA 3GTLC 3PIOS 4OINA 4G7OA 2BE5A 3GTKC 3RZOC 4KN4A 2PNWA 1QRTA 4J3CA 4GZYA 4BY1C 2G6GA 5GADW 1O0CA 1BDFA 4P2BA 5IP9C 3HOYC 2KXYA 4A3DC 4C2MC 1NXZA 3WODA 4JXXA 1EUQA 4Y52C 4A3CC 4YG2A 2A68A 1Y1VC 2NVYC 1R9TC 2B63C 4A3KC 3S2HC 4LJZA 1FEUA 3S17C 1YNJA 5C44C 4MQ9A 2R92C 2PJJA 4KMUA 2L5NA 1UDXA 5BNZA 5JVHS 4NOIA 2E2HC 5IP7C 2NVXC 4ZH4A 4OIRA 3HOZC 4A3EC 5C4XC 3GTJC 4UY88 2YU9C 3S1QC 4IO9S 2Z0YA 3H0GC 2R93C 3RZDC 1EUYA 1I3QC 5TMFA 4BBRC 2JA6C
chains in the Genus database with same CATH topology
4WFBS 4WFAS 1QRTA 4H4KA 1QTQA 3X1LB 3W2VB 4WCES 5GADW 5HL7S 1O0CA 4P2BA 1EXDA 4WF9S 1GTRA 2ZJPS 4JYZA 3CF5S 4JXXA 3AIIA 5GAGW 1ZJWA 1EUQA 1QRUA 5JVGS 4IOAS 4IOCS 2RE8A 1EUYA 2HZ7A 1O0BA 1FEUA 5GAEW 2ZJQS 2RD2A 1UDXA 5DM7S 1DFUP 1QRSA 5BNZA 5DM6S 5JVHS 4H3SA 1NYLA 3PIPS 3DLLS 1B75A 1D6KA 4UY88 1GTSA 5GAHW 4IO9S 4V194 5IZNA 4WFNS 3PIOS 4JXZA 2ZJRS 4U67S 3W2WB 3J7ZV
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFB S;  4WFA S;  1QRT A;  1QTQ A;  4WCE S;  5GAD W;  5HL7 S;  1O0C A;  4P2B A;  1EXD A;  4WF9 S;  1GTR A;  2ZJP S;  4JYZ A;  3CF5 S;  4JXX A;  3AII A;  5GAG W;  1ZJW A;  1EUQ A;  1QRU A;  5JVG S;  4IOA S;  4IOC S;  2RE8 A;  1EUY A;  2HZ7 A;  1O0B A;  1FEU A;  5GAE W;  2ZJQ S;  2RD2 A;  5DM7 S;  1DFU P;  1QRS A;  5BNZ A;  5DM6 S;  5JVH S;  4H3S A;  1NYL A;  3PIP S;  3DLL S;  1B75 A;  1D6K A;  4UY8 8;  1GTS A;  5GAH W;  4IO9 S;  5IZN A;  4WFN S;  3PIO S;  4JXZ A;  2ZJR S;  4U67 S;  3J7Z V; 
#chains in the Genus database with same CATH topology
 2JA5 C;  4XSZ A;  2CX8 A;  4WFA S;  2VUM C;  3DXJ A;  3I4M C;  3S1N C;  4WCE S;  3K7A C;  4XLP A;  3CZB A;  1TWH C;  2G5D A;  1IW7 A;  2KQ1 A;  3KW2 A;  5IYB C;  4JYZ A;  2A69 A;  5GAG W;  1ZJW A;  4OIQ A;  5JVG S;  4LLG A;  5FLM C;  2KPU A;  4C3J C;  4G7H A;  3S1R C;  4IOC S;  2JA8 C;  4BY7 C;  2HZ7 A;  1O0B A;  1K83 C;  1I6H C;  5IYD C;  2ZJQ S;  4QIW D;  2O5I A;  2RD2 A;  4AYB D;  2NWA A;  2A6E A;  4H3S A;  4BBS C;  1SMY A;  5IYC C;  4XLN A;  4A3I C;  3HOU C;  5GAH W;  3S2D C;  3S1M C;  4YFN A;  5IZN A;  2PPB A;  3PO3 C;  2ZJR S;  1TWG C;  4XSX A;  5TMC A;  1TWC C;  3H3V D;  3X1L B;  4H4K A;  1TWA C;  2Y0S D;  1I6V A;  1Y1W C;  2WAQ D;  4Y7N C;  3EQL A;  4X6A C;  1GTR A;  3LYW A;  4A3B C;  4LK1 A;  3GTP C;  1HQM A;  4YFX A;  1QRU A;  4BXX C;  1VHY A;  2EGV A;  3CQZ C;  3GTG C;  2AE0 X;  2PA8 D;  3HOV C;  2NVQ C;  4OIP A;  2GAE A;  4G7Z A;  1VHK A;  2A6H A;  5DM7 S;  4E8B A;  1QRS A;  4KN7 A;  4JK1 A;  4A93 C;  1NYL A;  3I4N C;  3DLL S;  1B75 A;  1D6K A;  1WCM C;  5HQH A;  4U67 S;  1TWF C;  5C4J C;  4Q4Z A;  2E2I C;  3HOW C;  4V19 4;  3FKI C;  4WFN S;  2PMZ D;  4L69 A;  4JXZ A;  1Z85 A;  2JA7 C;  3W2W B;  2EGW A;  3J7Z V;  3HKZ D;  4WFB S;  4QJV A;  3HOX C;  1SFO C;  2R7Z C;  1QTQ A;  3W2V B;  3M3Y C;  5HL7 S;  2CW0 A;  1EXD A;  4YFK A;  4WF9 S;  3GTM C;  2ZJP S;  2O5J A;  3CF5 S;  3AII A;  4C3I C;  4C3H C;  4OIO A;  4IOA S;  2RE8 A;  5C3E C;  1ZYR A;  4A3M C;  5GAE W;  4MEX A;  2NVT C;  3S16 C;  4A3J C;  2PIC A;  1DFU P;  2PI8 A;  4LK0 A;  3PO2 C;  3GTO C;  3S15 C;  1V6Z A;  5DM6 S;  4A3G C;  1I50 C;  3GTQ C;  3S14 C;  3M4O C;  3PIP S;  2WB1 D;  5D4D A;  4A3F C;  2E2J C;  4A3L C;  4Q5S A;  4MEY A;  1GTS A;  2L3U A;  1YNN A;  3GTL C;  3PIO S;  4OIN A;  4G7O A;  2BE5 A;  3GTK C;  3RZO C;  4KN4 A;  2PNW A;  1QRT A;  4J3C A;  4GZY A;  4BY1 C;  2G6G A;  5GAD W;  1O0C A;  1BDF A;  4P2B A;  5IP9 C;  3HOY C;  2KXY A;  4A3D C;  4C2M C;  1NXZ A;  3WOD A;  4JXX A;  1EUQ A;  4Y52 C;  4A3C C;  4YG2 A;  2A68 A;  1Y1V C;  2NVY C;  1R9T C;  2B63 C;  4A3K C;  3S2H C;  4LJZ A;  1FEU A;  3S17 C;  1YNJ A;  5C44 C;  4MQ9 A;  2R92 C;  2PJJ A;  4KMU A;  2L5N A;  1UDX A;  5BNZ A;  5JVH S;  4NOI A;  2E2H C;  5IP7 C;  2NVX C;  4ZH4 A;  4OIR A;  3HOZ C;  4A3E C;  5C4X C;  3GTJ C;  4UY8 8;  2YU9 C;  3S1Q C;  4IO9 S;  2Z0Y A;  3H0G C;  2R93 C;  3RZD C;  1EUY A;  1I3Q C;  5TMF A;  4BBR C;  2JA6 C; 
#chains in the Genus database with same CATH homology
 4WFB S;  4WFA S;  1QRT A;  4H4K A;  1QTQ A;  3X1L B;  3W2V B;  4WCE S;  5GAD W;  5HL7 S;  1O0C A;  4P2B A;  1EXD A;  4WF9 S;  1GTR A;  2ZJP S;  4JYZ A;  3CF5 S;  4JXX A;  3AII A;  5GAG W;  1ZJW A;  1EUQ A;  1QRU A;  5JVG S;  4IOA S;  4IOC S;  2RE8 A;  1EUY A;  2HZ7 A;  1O0B A;  1FEU A;  5GAE W;  2ZJQ S;  2RD2 A;  1UDX A;  5DM7 S;  1DFU P;  1QRS A;  5BNZ A;  5DM6 S;  5JVH S;  4H3S A;  1NYL A;  3PIP S;  3DLL S;  1B75 A;  1D6K A;  4UY8 8;  1GTS A;  5GAH W;  4IO9 S;  4V19 4;  5IZN A;  4WFN S;  3PIO S;  4JXZ A;  2ZJR S;  4U67 S;  3W2W B;  3J7Z V; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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