4WF9S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with telithromycin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 24
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wf9S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wf9S02
4WFNS 1EUYA 4IOCS 1O0BA 2RD2A 4JXXA 5BNZA 1O0CA 4WFBS 1EXDA 4WF9S 3CF5S 4P2BA 1QRUA 3J7ZV 2ZJQS 1GTSA 4IO9S 1QRTA 5DM7S 4U67S 2HZ7A 5GAEW 1QRSA 1EUQA 1DFUP 4JXZA 4H3SA 5JVHS 5DM6S 5GAGW 2ZJRS 1GTRA 4UY88 3PIPS 4JYZA 3PIOS 2RE8A 4WFAS 1ZJWA 5GADW 1NYLA 5JVGS 5HL7S 2ZJPS 1QTQA 5IZNA 3AIIA 4WCES 4IOAS 1FEUA 3DLLS 5GAHW 1B75A 1D6KA
chains in the Genus database with same CATH superfamily
4WFNS 4XLNA 4AYBD 4IOCS 4Y7NC 1O0BA 2KQ1A 4BXXC 2O5JA 2KXYA 4A93C 5C3EC 4LK0A 1Y1WC 1QRUA 2NVTC 2CX8A 3GTKC 3H3VD 4OIQA 5IYCC 1QRTA 3X1LB 2CW0A 1WCMC 1YNJA 2JA7C 1SFOC 1DFUP 2YU9C 5JVHS 2GAEA 3S1NC 4G7OA 4A3MC 3GTQC 2PA8D 1GTRA 4BY7C 3HOYC 4WFAS 3HOWC 3HOZC 4LK1A 2A69A 3I4MC 3RZOC 3GTJC 4A3IC 2R93C 1QTQA 5IZNA 1IW7A 1NXZA 3HKZD 1UDXA 1Z85A 2PI8A 5HQHA 2PMZD 2VUMC 2E2JC 1BDFA 3FKIC 3K7AC 1K83C 4A3CC 4XLPA 1SMYA 4OIRA 1I50C 4Y52C 2Z0YA 1O0CA 2EGVA 4LLGA 2E2HC 4G7HA 3CF5S 2A6EA 5IP7C 4H4KA 4A3KC 1I6HC 1VHYA 4GZYA 3CQZC 2NWAA 4MQ9A 4ZH4A 2WB1D 4Q5SA 2JA8C 1TWFC 5TMCA 1QRSA 1EUQA 1TWCC 1TWGC 5IP9C 4A3GC 4MEXA 5DM6S 5GAGW 3S2HC 4YG2A 2A6HA 1YNNA 3PIPS 2BE5A 3DXJA 3PIOS 2EGWA 4L69A 3WODA 1HQMA 1V6ZA 1R9TC 2ZJPS 2R92C 4V194 3AIIA 4WCES 4IOAS 2NVXC 4KN4A 1B75A 2PJJA 1EUYA 1TWAC 4A3LC 2JA6C 2L3UA 5C4XC 2RD2A 4JXXA 3S16C 5TMFA 4NOIA 4YFNA 4WFBS 3HOXC 4A3JC 4A3FC 3S1RC 2PPBA 3PO2C 4C2MC 1Y1VC 4KMUA 3J7ZV 3GTLC 2ZJQS 5DM7S 4OIPA 2R7ZC 3GTOC 3GTPC 1I3QC 4LJZA 4JXZA 2AE0X 4H3SA 1I6VA 5C4JC 4E8BA 3S17C 3W2VB 4X6AC 5GADW 1NYLA 4XSXA 4BBRC 2B63C 3S14C 3KW2A 4C3HC 3RZDC 3CZBA 4C3IC 3EQLA 4YFXA 1FEUA 3DLLS 4G7ZA 4XSZA 2A68A 5C44C 4A3EC 1TWHC 2G5DA 2JA5C 5FLMC 3PO3C 5BNZA 1EXDA 4WF9S 3GTMC 2WAQD 4OINA 2KPUA 4JK1A 4P2BA 4OIOA 1ZYRA 3M4OC 1GTSA 4IO9S 3S2DC 2PICA 4U67S 2O5IA 2HZ7A 4J3CA 3W2WB 5GAEW 4YFKA 3M3YC 5IYDC 2E2IC 2Y0SD 4Q4ZA 2ZJRS 2L5NA 2PNWA 4UY88 4JYZA 4BY1C 4QIWD 3S1QC 2RE8A 2NVYC 1ZJWA 4QJVA 5JVGS 3HOVC 5HL7S 5IYBC 4BBSC 4MEYA 2G6GA 1VHKA 3LYWA 2NVQC 3H0GC 3S1MC 4A3BC 3HOUC 3I4NC 3S15C 4A3DC 4KN7A 5GAHW 5D4DA 1D6KA 3GTGC 4C3JC
chains in the Genus database with same CATH topology
4WFNS 1EUYA 4IOCS 1O0BA 2RD2A 4JXXA 5BNZA 1O0CA 4WFBS 1EXDA 4WF9S 3CF5S 4H4KA 4P2BA 1QRUA 3J7ZV 2ZJQS 1GTSA 4IO9S 1QRTA 5DM7S 4U67S 3X1LB 2HZ7A 3W2WB 5GAEW 1QRSA 1EUQA 1DFUP 4JXZA 4H3SA 5JVHS 3W2VB 5DM6S 5GAGW 2ZJRS 1GTRA 4UY88 3PIPS 4JYZA 3PIOS 2RE8A 4WFAS 1ZJWA 5GADW 1NYLA 5JVGS 5HL7S 2ZJPS 1QTQA 5IZNA 3AIIA 4WCES 4V194 1UDXA 4IOAS 1FEUA 3DLLS 5GAHW 1B75A 1D6KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFN S;  1EUY A;  4IOC S;  1O0B A;  2RD2 A;  4JXX A;  5BNZ A;  1O0C A;  4WFB S;  1EXD A;  4WF9 S;  3CF5 S;  4P2B A;  1QRU A;  3J7Z V;  2ZJQ S;  1GTS A;  4IO9 S;  1QRT A;  5DM7 S;  4U67 S;  2HZ7 A;  5GAE W;  1QRS A;  1EUQ A;  1DFU P;  4JXZ A;  4H3S A;  5JVH S;  5DM6 S;  5GAG W;  2ZJR S;  1GTR A;  4UY8 8;  3PIP S;  4JYZ A;  3PIO S;  2RE8 A;  4WFA S;  1ZJW A;  5GAD W;  1NYL A;  5JVG S;  5HL7 S;  2ZJP S;  1QTQ A;  5IZN A;  3AII A;  4WCE S;  4IOA S;  1FEU A;  3DLL S;  5GAH W;  1B75 A;  1D6K A; 
#chains in the Genus database with same CATH topology
 4WFN S;  4XLN A;  4AYB D;  4IOC S;  4Y7N C;  1O0B A;  2KQ1 A;  4BXX C;  2O5J A;  2KXY A;  4A93 C;  5C3E C;  4LK0 A;  1Y1W C;  1QRU A;  2NVT C;  2CX8 A;  3GTK C;  3H3V D;  4OIQ A;  5IYC C;  1QRT A;  3X1L B;  2CW0 A;  1WCM C;  1YNJ A;  2JA7 C;  1SFO C;  1DFU P;  2YU9 C;  5JVH S;  2GAE A;  3S1N C;  4G7O A;  4A3M C;  3GTQ C;  2PA8 D;  1GTR A;  4BY7 C;  3HOY C;  4WFA S;  3HOW C;  3HOZ C;  4LK1 A;  2A69 A;  3I4M C;  3RZO C;  3GTJ C;  4A3I C;  2R93 C;  1QTQ A;  5IZN A;  1IW7 A;  1NXZ A;  3HKZ D;  1UDX A;  1Z85 A;  2PI8 A;  5HQH A;  2PMZ D;  2VUM C;  2E2J C;  1BDF A;  3FKI C;  3K7A C;  1K83 C;  4A3C C;  4XLP A;  1SMY A;  4OIR A;  1I50 C;  4Y52 C;  2Z0Y A;  1O0C A;  2EGV A;  4LLG A;  2E2H C;  4G7H A;  3CF5 S;  2A6E A;  5IP7 C;  4H4K A;  4A3K C;  1I6H C;  1VHY A;  4GZY A;  3CQZ C;  2NWA A;  4MQ9 A;  4ZH4 A;  2WB1 D;  4Q5S A;  2JA8 C;  1TWF C;  5TMC A;  1QRS A;  1EUQ A;  1TWC C;  1TWG C;  5IP9 C;  4A3G C;  4MEX A;  5DM6 S;  5GAG W;  3S2H C;  4YG2 A;  2A6H A;  1YNN A;  3PIP S;  2BE5 A;  3DXJ A;  3PIO S;  2EGW A;  4L69 A;  3WOD A;  1HQM A;  1V6Z A;  1R9T C;  2ZJP S;  2R92 C;  4V19 4;  3AII A;  4WCE S;  4IOA S;  2NVX C;  4KN4 A;  1B75 A;  2PJJ A;  1EUY A;  1TWA C;  4A3L C;  2JA6 C;  2L3U A;  5C4X C;  2RD2 A;  4JXX A;  3S16 C;  5TMF A;  4NOI A;  4YFN A;  4WFB S;  3HOX C;  4A3J C;  4A3F C;  3S1R C;  2PPB A;  3PO2 C;  4C2M C;  1Y1V C;  4KMU A;  3J7Z V;  3GTL C;  2ZJQ S;  5DM7 S;  4OIP A;  2R7Z C;  3GTO C;  3GTP C;  1I3Q C;  4LJZ A;  4JXZ A;  2AE0 X;  4H3S A;  1I6V A;  5C4J C;  4E8B A;  3S17 C;  3W2V B;  4X6A C;  5GAD W;  1NYL A;  4XSX A;  4BBR C;  2B63 C;  3S14 C;  3KW2 A;  4C3H C;  3RZD C;  3CZB A;  4C3I C;  3EQL A;  4YFX A;  1FEU A;  3DLL S;  4G7Z A;  4XSZ A;  2A68 A;  5C44 C;  4A3E C;  1TWH C;  2G5D A;  2JA5 C;  5FLM C;  3PO3 C;  5BNZ A;  1EXD A;  4WF9 S;  3GTM C;  2WAQ D;  4OIN A;  2KPU A;  4JK1 A;  4P2B A;  4OIO A;  1ZYR A;  3M4O C;  1GTS A;  4IO9 S;  3S2D C;  2PIC A;  4U67 S;  2O5I A;  2HZ7 A;  4J3C A;  3W2W B;  5GAE W;  4YFK A;  3M3Y C;  5IYD C;  2E2I C;  2Y0S D;  4Q4Z A;  2ZJR S;  2L5N A;  2PNW A;  4UY8 8;  4JYZ A;  4BY1 C;  4QIW D;  3S1Q C;  2RE8 A;  2NVY C;  1ZJW A;  4QJV A;  5JVG S;  3HOV C;  5HL7 S;  5IYB C;  4BBS C;  4MEY A;  2G6G A;  1VHK A;  3LYW A;  2NVQ C;  3H0G C;  3S1M C;  4A3B C;  3HOU C;  3I4N C;  3S15 C;  4A3D C;  4KN7 A;  5GAH W;  5D4D A;  1D6K A;  3GTG C;  4C3J C; 
#chains in the Genus database with same CATH homology
 4WFN S;  1EUY A;  4IOC S;  1O0B A;  2RD2 A;  4JXX A;  5BNZ A;  1O0C A;  4WFB S;  1EXD A;  4WF9 S;  3CF5 S;  4H4K A;  4P2B A;  1QRU A;  3J7Z V;  2ZJQ S;  1GTS A;  4IO9 S;  1QRT A;  5DM7 S;  4U67 S;  3X1L B;  2HZ7 A;  3W2W B;  5GAE W;  1QRS A;  1EUQ A;  1DFU P;  4JXZ A;  4H3S A;  5JVH S;  3W2V B;  5DM6 S;  5GAG W;  2ZJR S;  1GTR A;  4UY8 8;  3PIP S;  4JYZ A;  3PIO S;  2RE8 A;  4WFA S;  1ZJW A;  5GAD W;  1NYL A;  5JVG S;  5HL7 S;  2ZJP S;  1QTQ A;  5IZN A;  3AII A;  4WCE S;  4V19 4;  1UDX A;  4IOA S;  1FEU A;  3DLL S;  5GAH W;  1B75 A;  1D6K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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