2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
molecule tags Rna methyltransferase
source organism Aquifex aeolicus
molecule keywords UPF0088 protein aq_165
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
4H3YA 2YY8A 4XBOA 3O7BA 4YVGA 2V3JA 1VHKA 4YPWA 1V6ZA 2CX8A 4MCBA 4YPZA 4YQ3A 3N4JA 1ZJRA 3IEFA 4L69A 4YQ7A 1Z85A 4YQSA 2Z0YA 4YQBA 4YQ5A 4X3MA 3NK7A 4YPYA 5GMBA 1K3RA 1OY5A 1MXIA 4YPXA 4IG6A 4YQ9A 3L8UA 4CNFA 2V3KA 3BBHA 1UAJA 3KY7A 4YQRA 1VH0A 5FAIA 1IPAA 4CNGA 1X7OA 1UALA 4JALA 4YQOA 4KDZA 2O3AA 4YQ1A 3KNUA 3AI9X 4YQ8A 3ILKA 3BBEA 4MCCA 4YQTA 3ONPA 4H3ZA 3BBDA 4E8BA 5CO4A 4YVJA 3KTYA 4CNDA 4YQLA 3QUVA 2NWAA 4J3CA 4YQPA 3AXZA 1VHYA 4YQDA 2I6DA 3E5YA 2QWVA 4JAKA 4YQ2A 1NS5A 5GMCA 4FAKA 3OINA 1O6DA 4YQ6A 4YVIA 4YQGA 4YQ0A 3IC6A 3OIIA 1TO0A 5D9FA 4KGNA 1NXZA 4YQIA 4YQCA 5GM8A 1J85A 4MCDA 3GYQA 4YQKA 2EGVA 2EGWA 3OIJA 1UAMA 4X3LA 3DCMX 1V2XA 4PZKA 3KW2A 2HA8A 3AIAA 4YQJA 2QMMA 4YVHA 3N4KA 4RG1A 4YQ4A 4YQNA 1P9PA 3NK6A 1GZ0A 4YVKA 4YQQA 1X7PA 4CNEA 4YQAA 1UAKA
chains in the Genus database with same CATH superfamily
4H3YA 2YY8A 4XBOA 4WFNS 3O7BA 4YVGA 2V3JA 1VHKA 4V194 1O0CA 1V6ZA 2CX8A 4MCBA 1QRUA 4YPWA 3N4JA 4YPZA 1ZJRA 4YQ3A 1QRSA 3IEFA 4L69A 4YQ7A 4U67S 1Z85A 4YQSA 5GAEW 2PNWA 2Z0YA 4YQBA 4YQ5A 4X3MA 3NK7A 4YPYA 5GMBA 1K3RA 4H4KA 1NYLA 1OY5A 3CZBA 4WFBS 4WCES 1MXIA 4JXZA 5JVHS 4JWHA 4YPXA 3W2WB 4IO9S 4UY88 1EUQA 4IG6A 3J7ZV 4YQ9A 3L8UA 4CNFA 2V3KA 3BBHA 1GTRA 3AIIA 1UAJA 3KY7A 4YQRA 1VH0A 5FAIA 1O0BA 5DM6S 1IPAA 4CNGA 4JWJA 1X7OA 1UALA 4JALA 1UDXA 4YQOA 4KDZA 2O3AA 4IOAS 2G6GA 3KNUA 3AI9X 4YQ1A 4YQ8A 3ILKA 3BBEA 4MCCA 2HZ7A 4H3SA 4YQTA 5JVGS 3ONPA 2RD2A 4H3ZA 2ZJPS 5GADW 3BBDA 1D6KA 2PI8A 1GTSA 4E8BA 2AE0X 2G5DA 5CO4A 4YVJA 4JXXA 3KTYA 4CNDA 4YQLA 4WFAS 3QUVA 2NWAA 4J3CA 4YQPA 3AXZA 1QTQA 1VHYA 1FEUA 2I6DA 4YQDA 1EUYA 3E5YA 2QWVA 4JAKA 4WF9S 4YQ2A 1NS5A 3PIOS 3DLLS 5GMCA 4FAKA 2PICA 3OINA 1O6DA 4YQ6A 5HL7S 4YVIA 4YQGA 3CF5S 4YQ0A 2RE8A 3IC6A 3OIIA 1DFUP 3PIPS 1TO0A 5D9FA 4KGNA 1NXZA 2PJJA 4YQIA 4YQCA 1QRTA 5GM8A 5DM7S 1J85A 4P2BA 1B75A 4MCDA 3GYQA 4YQKA 2EGVA 2EGWA 3OIJA 1UAMA 4FMWA 4X3LA 3DCMX 4JWGA 3X1LB 1V2XA 2ZJQS 4PZKA 5BNZA 3KW2A 2HA8A 3AIAA 4YQJA 2QMMA 4YVHA 3N4KA 5GAGW 4IOCS 4JWFA 4RG1A 5IZNA 5GAHW 4YQ4A 3W2VB 4YQNA 1P9PA 1ZJWA 1EXDA 3NK6A 2ZJRS 1GZ0A 4YVKA 2GAEA 4JYZA 4YQQA 1X7PA 4CNEA 4YQAA 1UAKA
chains in the Genus database with same CATH topology
4H3YA 2YY8A 4XBOA 3O7BA 4YVGA 2V3JA 1VHKA 4YPWA 1V6ZA 2CX8A 4MCBA 4YPZA 4YQ3A 3N4JA 1ZJRA 3IEFA 4L69A 4YQ7A 1Z85A 4YQSA 2Z0YA 4YQBA 4YQ5A 4X3MA 3NK7A 4YPYA 5GMBA 1K3RA 1OY5A 1MXIA 4JWHA 4YPXA 4IG6A 4YQ9A 3L8UA 4CNFA 2V3KA 3BBHA 1UAJA 3KY7A 4YQRA 1VH0A 5FAIA 1IPAA 4CNGA 4JWJA 1X7OA 1UALA 4JALA 4YQOA 4KDZA 2O3AA 4YQ1A 3KNUA 3AI9X 4YQ8A 3ILKA 3BBEA 4MCCA 4YQTA 3ONPA 4H3ZA 3BBDA 4E8BA 5CO4A 4YVJA 3KTYA 4CNDA 4YQLA 3QUVA 2NWAA 4J3CA 4YQPA 3AXZA 1VHYA 4YQDA 2I6DA 3E5YA 2QWVA 4JAKA 4YQ2A 1NS5A 5GMCA 4FAKA 3OINA 1O6DA 4YQ6A 4YVIA 4YQGA 4YQ0A 3IC6A 3OIIA 1TO0A 5D9FA 4KGNA 1NXZA 4YQIA 4YQCA 5GM8A 1J85A 4MCDA 3GYQA 4YQKA 2EGVA 2EGWA 3OIJA 1UAMA 4FMWA 4X3LA 3DCMX 4JWGA 1V2XA 4PZKA 3KW2A 2HA8A 3AIAA 4YQJA 2QMMA 4YVHA 3N4KA 4JWFA 4RG1A 4YQ4A 4YQNA 1P9PA 3NK6A 1GZ0A 4YVKA 4YQQA 1X7PA 4CNEA 4YQAA 1UAKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4H3Y A;  2YY8 A;  4XBO A;  3O7B A;  4YVG A;  2V3J A;  1VHK A;  4YPW A;  1V6Z A;  2CX8 A;  4MCB A;  4YPZ A;  4YQ3 A;  3N4J A;  1ZJR A;  3IEF A;  4L69 A;  4YQ7 A;  1Z85 A;  4YQS A;  2Z0Y A;  4YQB A;  4YQ5 A;  4X3M A;  3NK7 A;  4YPY A;  5GMB A;  1K3R A;  1OY5 A;  1MXI A;  4YPX A;  4IG6 A;  4YQ9 A;  3L8U A;  4CNF A;  2V3K A;  3BBH A;  1UAJ A;  3KY7 A;  4YQR A;  1VH0 A;  5FAI A;  1IPA A;  4CNG A;  1X7O A;  1UAL A;  4JAL A;  4YQO A;  4KDZ A;  2O3A A;  4YQ1 A;  3KNU A;  3AI9 X;  4YQ8 A;  3ILK A;  3BBE A;  4MCC A;  4YQT A;  3ONP A;  4H3Z A;  3BBD A;  4E8B A;  5CO4 A;  4YVJ A;  3KTY A;  4CND A;  4YQL A;  3QUV A;  2NWA A;  4J3C A;  4YQP A;  3AXZ A;  1VHY A;  4YQD A;  2I6D A;  3E5Y A;  2QWV A;  4JAK A;  4YQ2 A;  1NS5 A;  5GMC A;  4FAK A;  3OIN A;  1O6D A;  4YQ6 A;  4YVI A;  4YQG A;  4YQ0 A;  3IC6 A;  3OII A;  1TO0 A;  5D9F A;  4KGN A;  1NXZ A;  4YQI A;  4YQC A;  5GM8 A;  1J85 A;  4MCD A;  3GYQ A;  4YQK A;  2EGV A;  2EGW A;  3OIJ A;  1UAM A;  4X3L A;  3DCM X;  1V2X A;  4PZK A;  3KW2 A;  2HA8 A;  3AIA A;  4YQJ A;  2QMM A;  4YVH A;  3N4K A;  4RG1 A;  4YQ4 A;  4YQN A;  1P9P A;  3NK6 A;  1GZ0 A;  4YVK A;  4YQQ A;  1X7P A;  4CNE A;  4YQA A;  1UAK A; 
#chains in the Genus database with same CATH topology
 4H3Y A;  2YY8 A;  4XBO A;  4WFN S;  3O7B A;  4YVG A;  2V3J A;  1VHK A;  4V19 4;  1O0C A;  1V6Z A;  2CX8 A;  4MCB A;  1QRU A;  4YPW A;  3N4J A;  4YPZ A;  1ZJR A;  4YQ3 A;  1QRS A;  3IEF A;  4L69 A;  4YQ7 A;  4U67 S;  1Z85 A;  4YQS A;  5GAE W;  2PNW A;  2Z0Y A;  4YQB A;  4YQ5 A;  4X3M A;  3NK7 A;  4YPY A;  5GMB A;  1K3R A;  4H4K A;  1NYL A;  1OY5 A;  3CZB A;  4WFB S;  4WCE S;  1MXI A;  4JXZ A;  5JVH S;  4JWH A;  4YPX A;  3W2W B;  4IO9 S;  4UY8 8;  1EUQ A;  4IG6 A;  3J7Z V;  4YQ9 A;  3L8U A;  4CNF A;  2V3K A;  3BBH A;  1GTR A;  3AII A;  1UAJ A;  3KY7 A;  4YQR A;  1VH0 A;  5FAI A;  1O0B A;  5DM6 S;  1IPA A;  4CNG A;  4JWJ A;  1X7O A;  1UAL A;  4JAL A;  1UDX A;  4YQO A;  4KDZ A;  2O3A A;  4IOA S;  2G6G A;  3KNU A;  3AI9 X;  4YQ1 A;  4YQ8 A;  3ILK A;  3BBE A;  4MCC A;  2HZ7 A;  4H3S A;  4YQT A;  5JVG S;  3ONP A;  2RD2 A;  4H3Z A;  2ZJP S;  5GAD W;  3BBD A;  1D6K A;  2PI8 A;  1GTS A;  4E8B A;  2AE0 X;  2G5D A;  5CO4 A;  4YVJ A;  4JXX A;  3KTY A;  4CND A;  4YQL A;  4WFA S;  3QUV A;  2NWA A;  4J3C A;  4YQP A;  3AXZ A;  1QTQ A;  1VHY A;  1FEU A;  2I6D A;  4YQD A;  1EUY A;  3E5Y A;  2QWV A;  4JAK A;  4WF9 S;  4YQ2 A;  1NS5 A;  3PIO S;  3DLL S;  5GMC A;  4FAK A;  2PIC A;  3OIN A;  1O6D A;  4YQ6 A;  5HL7 S;  4YVI A;  4YQG A;  3CF5 S;  4YQ0 A;  2RE8 A;  3IC6 A;  3OII A;  1DFU P;  3PIP S;  1TO0 A;  5D9F A;  4KGN A;  1NXZ A;  2PJJ A;  4YQI A;  4YQC A;  1QRT A;  5GM8 A;  5DM7 S;  1J85 A;  4P2B A;  1B75 A;  4MCD A;  3GYQ A;  4YQK A;  2EGV A;  2EGW A;  3OIJ A;  1UAM A;  4FMW A;  4X3L A;  3DCM X;  4JWG A;  3X1L B;  1V2X A;  2ZJQ S;  4PZK A;  5BNZ A;  3KW2 A;  2HA8 A;  3AIA A;  4YQJ A;  2QMM A;  4YVH A;  3N4K A;  5GAG W;  4IOC S;  4JWF A;  4RG1 A;  5IZN A;  5GAH W;  4YQ4 A;  3W2V B;  4YQN A;  1P9P A;  1ZJW A;  1EXD A;  3NK6 A;  2ZJR S;  1GZ0 A;  4YVK A;  2GAE A;  4JYZ A;  4YQQ A;  1X7P A;  4CNE A;  4YQA A;  1UAK A; 
#chains in the Genus database with same CATH homology
 4H3Y A;  2YY8 A;  4XBO A;  3O7B A;  4YVG A;  2V3J A;  1VHK A;  4YPW A;  1V6Z A;  2CX8 A;  4MCB A;  4YPZ A;  4YQ3 A;  3N4J A;  1ZJR A;  3IEF A;  4L69 A;  4YQ7 A;  1Z85 A;  4YQS A;  2Z0Y A;  4YQB A;  4YQ5 A;  4X3M A;  3NK7 A;  4YPY A;  5GMB A;  1K3R A;  1OY5 A;  1MXI A;  4JWH A;  4YPX A;  4IG6 A;  4YQ9 A;  3L8U A;  4CNF A;  2V3K A;  3BBH A;  1UAJ A;  3KY7 A;  4YQR A;  1VH0 A;  5FAI A;  1IPA A;  4CNG A;  4JWJ A;  1X7O A;  1UAL A;  4JAL A;  4YQO A;  4KDZ A;  2O3A A;  4YQ1 A;  3KNU A;  3AI9 X;  4YQ8 A;  3ILK A;  3BBE A;  4MCC A;  4YQT A;  3ONP A;  4H3Z A;  3BBD A;  4E8B A;  5CO4 A;  4YVJ A;  3KTY A;  4CND A;  4YQL A;  3QUV A;  2NWA A;  4J3C A;  4YQP A;  3AXZ A;  1VHY A;  4YQD A;  2I6D A;  3E5Y A;  2QWV A;  4JAK A;  4YQ2 A;  1NS5 A;  5GMC A;  4FAK A;  3OIN A;  1O6D A;  4YQ6 A;  4YVI A;  4YQG A;  4YQ0 A;  3IC6 A;  3OII A;  1TO0 A;  5D9F A;  4KGN A;  1NXZ A;  4YQI A;  4YQC A;  5GM8 A;  1J85 A;  4MCD A;  3GYQ A;  4YQK A;  2EGV A;  2EGW A;  3OIJ A;  1UAM A;  4FMW A;  4X3L A;  3DCM X;  4JWG A;  1V2X A;  4PZK A;  3KW2 A;  2HA8 A;  3AIA A;  4YQJ A;  2QMM A;  4YVH A;  3N4K A;  4JWF A;  4RG1 A;  4YQ4 A;  4YQN A;  1P9P A;  3NK6 A;  1GZ0 A;  4YVK A;  4YQQ A;  1X7P A;  4CNE A;  4YQA A;  1UAK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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