2EGWA

Crystal structure of rrna methyltransferase with sah ligand
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of rRNA methyltransferase with SAH ligand
rcsb
molecule tags Rna methyltransferase
source organism Aquifex aeolicus
molecule keywords UPF0088 protein aq_165
total genus 71
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egwA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egwA02
4CNDA 1J85A 4YQLA 4YQPA 2QMMA 3KNUA 1TO0A 4YQ7A 2V3JA 3N4JA 3BBEA 4CNGA 1O6DA 3ILKA 4YQ1A 4YQ0A 1Z85A 3O7BA 4CNEA 4YVHA 1IPAA 2EGVA 1K3RA 1UAKA 3KTYA 4J3CA 1X7PA 2HA8A 4YQBA 1VHKA 3IEFA 1UAMA 5GMCA 4YQSA 3AIAA 4YQRA 5GMBA 4FAKA 1NXZA 4YQTA 4E8BA 4YVKA 4YPZA 1VH0A 4JALA 4YPYA 1MXIA 1UAJA 2CX8A 4YQQA 4MCBA 5CO4A 4YQNA 4YPWA 4YQ2A 1GZ0A 3L8UA 4YQAA 4YQCA 2Z0YA 3GYQA 3DCMX 4JAKA 5FAIA 4YVIA 3OIJA 3QUVA 4H3YA 4YQ8A 3IC6A 4CNFA 3OIIA 2V3KA 4YQDA 4YVJA 1VHYA 4KDZA 4YQKA 4YQOA 4X3MA 1OY5A 4YQ6A 3E5YA 3KW2A 3ONPA 3NK6A 1ZJRA 4YQGA 4L69A 4YQ4A 4X3LA 5GM8A 4H3ZA 4YPXA 3KY7A 4XBOA 2NWAA 1NS5A 3N4KA 2O3AA 4IG6A 4YQ9A 3AXZA 4YVGA 4PZKA 4YQ3A 2I6DA 1P9PA 4KGNA 2QWVA 3BBDA 5D9FA 2YY8A 4YQIA 1UALA 3OINA 4RG1A 1V6ZA 4MCDA 4MCCA 4YQ5A 2EGWA 3NK7A 3AI9X 4YQJA 3BBHA 1X7OA 1V2XA
chains in the Genus database with same CATH superfamily
4CNDA 1J85A 1D6KA 4YQLA 2GAEA 4YQPA 2QMMA 3KNUA 1TO0A 4YQ7A 2V3JA 5DM7S 3W2VB 1GTRA 4JXZA 4H4KA 3N4JA 4WCES 4JYZA 4P2BA 3BBEA 4CNGA 4WF9S 1O6DA 3ILKA 4YQ1A 4JWHA 4YQ0A 1Z85A 3O7BA 4CNEA 4YVHA 1IPAA 2EGVA 1K3RA 1UAKA 1EXDA 1O0BA 3KTYA 4J3CA 4H3SA 1X7PA 2HA8A 2PJJA 4YQBA 2RD2A 1QRUA 1VHKA 4IOAS 3IEFA 1UAMA 5GMCA 4YQSA 4UY88 3AIAA 4FMWA 4YQRA 5GMBA 1GTSA 4FAKA 1NXZA 4YQTA 4E8BA 4YVKA 1B75A 4YPZA 3PIOS 4WFNS 5JVGS 4JXXA 1VH0A 4JALA 4YPYA 1MXIA 1UAJA 2ZJPS 2CX8A 1QRSA 4YQQA 5GAHW 1NYLA 3X1LB 4MCBA 5CO4A 4YQNA 4YPWA 4YQ2A 2ZJQS 5JVHS 1GZ0A 3L8UA 4YQAA 4WFAS 4YQCA 2Z0YA 3GYQA 3DCMX 4JAKA 4JWFA 4V194 5FAIA 4YVIA 3OIJA 3QUVA 4H3YA 4YQ8A 2RE8A 3IC6A 4CNFA 3OIIA 4JWGA 2G6GA 2V3KA 4YQDA 1EUQA 1QTQA 4YVJA 2HZ7A 1VHYA 4KDZA 2G5DA 1UDXA 1EUYA 3DLLS 2ZJRS 5HL7S 3CF5S 4YQKA 4YQOA 1FEUA 4X3MA 4JWJA 1OY5A 5IZNA 1DFUP 4IO9S 4YQ6A 3E5YA 4U67S 2PICA 3PIPS 1QRTA 3KW2A 2PNWA 5GAEW 3J7ZV 3ONPA 3NK6A 1ZJRA 4YQGA 4L69A 5GAGW 4YQ4A 4X3LA 5GM8A 4H3ZA 4IOCS 4YPXA 3CZBA 3AIIA 3KY7A 4XBOA 2NWAA 1O0CA 1NS5A 2PI8A 3N4KA 2O3AA 1ZJWA 2AE0X 4IG6A 4YQ9A 3AXZA 4YVGA 4PZKA 4YQ3A 5DM6S 2I6DA 1P9PA 4KGNA 2QWVA 3BBDA 5BNZA 4WFBS 5D9FA 2YY8A 4YQIA 1UALA 3OINA 4RG1A 1V6ZA 4MCDA 5GADW 4MCCA 4YQ5A 2EGWA 3NK7A 3AI9X 4YQJA 3BBHA 3W2WB 1X7OA 1V2XA
chains in the Genus database with same CATH topology
4CNDA 1J85A 4YQLA 4YQPA 2QMMA 3KNUA 1TO0A 4YQ7A 2V3JA 3N4JA 3BBEA 4CNGA 1O6DA 3ILKA 4YQ1A 4JWHA 4YQ0A 1Z85A 3O7BA 4CNEA 4YVHA 1IPAA 2EGVA 1K3RA 1UAKA 3KTYA 4J3CA 1X7PA 2HA8A 4YQBA 1VHKA 3IEFA 1UAMA 5GMCA 4YQSA 3AIAA 4FMWA 4YQRA 5GMBA 4FAKA 1NXZA 4YQTA 4E8BA 4YVKA 4YPZA 1VH0A 4JALA 4YPYA 1MXIA 1UAJA 2CX8A 4YQQA 4MCBA 5CO4A 4YQNA 4YPWA 4YQ2A 1GZ0A 3L8UA 4YQAA 4YQCA 2Z0YA 3GYQA 3DCMX 4JAKA 4JWFA 5FAIA 4YVIA 3OIJA 3QUVA 4H3YA 4YQ8A 3IC6A 4CNFA 3OIIA 4JWGA 2V3KA 4YQDA 4YVJA 1VHYA 4KDZA 4YQKA 4YQOA 4X3MA 4JWJA 1OY5A 4YQ6A 3E5YA 3KW2A 3ONPA 3NK6A 1ZJRA 4YQGA 4L69A 4YQ4A 4X3LA 5GM8A 4H3ZA 4YPXA 3KY7A 4XBOA 2NWAA 1NS5A 3N4KA 2O3AA 4IG6A 4YQ9A 3AXZA 4YVGA 4PZKA 4YQ3A 2I6DA 1P9PA 4KGNA 2QWVA 3BBDA 5D9FA 2YY8A 4YQIA 1UALA 3OINA 4RG1A 1V6ZA 4MCDA 4MCCA 4YQ5A 2EGWA 3NK7A 3AI9X 4YQJA 3BBHA 1X7OA 1V2XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CND A;  1J85 A;  4YQL A;  4YQP A;  2QMM A;  3KNU A;  1TO0 A;  4YQ7 A;  2V3J A;  3N4J A;  3BBE A;  4CNG A;  1O6D A;  3ILK A;  4YQ1 A;  4YQ0 A;  1Z85 A;  3O7B A;  4CNE A;  4YVH A;  1IPA A;  2EGV A;  1K3R A;  1UAK A;  3KTY A;  4J3C A;  1X7P A;  2HA8 A;  4YQB A;  1VHK A;  3IEF A;  1UAM A;  5GMC A;  4YQS A;  3AIA A;  4YQR A;  5GMB A;  4FAK A;  1NXZ A;  4YQT A;  4E8B A;  4YVK A;  4YPZ A;  1VH0 A;  4JAL A;  4YPY A;  1MXI A;  1UAJ A;  2CX8 A;  4YQQ A;  4MCB A;  5CO4 A;  4YQN A;  4YPW A;  4YQ2 A;  1GZ0 A;  3L8U A;  4YQA A;  4YQC A;  2Z0Y A;  3GYQ A;  3DCM X;  4JAK A;  5FAI A;  4YVI A;  3OIJ A;  3QUV A;  4H3Y A;  4YQ8 A;  3IC6 A;  4CNF A;  3OII A;  2V3K A;  4YQD A;  4YVJ A;  1VHY A;  4KDZ A;  4YQK A;  4YQO A;  4X3M A;  1OY5 A;  4YQ6 A;  3E5Y A;  3KW2 A;  3ONP A;  3NK6 A;  1ZJR A;  4YQG A;  4L69 A;  4YQ4 A;  4X3L A;  5GM8 A;  4H3Z A;  4YPX A;  3KY7 A;  4XBO A;  2NWA A;  1NS5 A;  3N4K A;  2O3A A;  4IG6 A;  4YQ9 A;  3AXZ A;  4YVG A;  4PZK A;  4YQ3 A;  2I6D A;  1P9P A;  4KGN A;  2QWV A;  3BBD A;  5D9F A;  2YY8 A;  4YQI A;  1UAL A;  3OIN A;  4RG1 A;  1V6Z A;  4MCD A;  4MCC A;  4YQ5 A;  2EGW A;  3NK7 A;  3AI9 X;  4YQJ A;  3BBH A;  1X7O A;  1V2X A; 
#chains in the Genus database with same CATH topology
 4CND A;  1J85 A;  1D6K A;  4YQL A;  2GAE A;  4YQP A;  2QMM A;  3KNU A;  1TO0 A;  4YQ7 A;  2V3J A;  5DM7 S;  3W2V B;  1GTR A;  4JXZ A;  4H4K A;  3N4J A;  4WCE S;  4JYZ A;  4P2B A;  3BBE A;  4CNG A;  4WF9 S;  1O6D A;  3ILK A;  4YQ1 A;  4JWH A;  4YQ0 A;  1Z85 A;  3O7B A;  4CNE A;  4YVH A;  1IPA A;  2EGV A;  1K3R A;  1UAK A;  1EXD A;  1O0B A;  3KTY A;  4J3C A;  4H3S A;  1X7P A;  2HA8 A;  2PJJ A;  4YQB A;  2RD2 A;  1QRU A;  1VHK A;  4IOA S;  3IEF A;  1UAM A;  5GMC A;  4YQS A;  4UY8 8;  3AIA A;  4FMW A;  4YQR A;  5GMB A;  1GTS A;  4FAK A;  1NXZ A;  4YQT A;  4E8B A;  4YVK A;  1B75 A;  4YPZ A;  3PIO S;  4WFN S;  5JVG S;  4JXX A;  1VH0 A;  4JAL A;  4YPY A;  1MXI A;  1UAJ A;  2ZJP S;  2CX8 A;  1QRS A;  4YQQ A;  5GAH W;  1NYL A;  3X1L B;  4MCB A;  5CO4 A;  4YQN A;  4YPW A;  4YQ2 A;  2ZJQ S;  5JVH S;  1GZ0 A;  3L8U A;  4YQA A;  4WFA S;  4YQC A;  2Z0Y A;  3GYQ A;  3DCM X;  4JAK A;  4JWF A;  4V19 4;  5FAI A;  4YVI A;  3OIJ A;  3QUV A;  4H3Y A;  4YQ8 A;  2RE8 A;  3IC6 A;  4CNF A;  3OII A;  4JWG A;  2G6G A;  2V3K A;  4YQD A;  1EUQ A;  1QTQ A;  4YVJ A;  2HZ7 A;  1VHY A;  4KDZ A;  2G5D A;  1UDX A;  1EUY A;  3DLL S;  2ZJR S;  5HL7 S;  3CF5 S;  4YQK A;  4YQO A;  1FEU A;  4X3M A;  4JWJ A;  1OY5 A;  5IZN A;  1DFU P;  4IO9 S;  4YQ6 A;  3E5Y A;  4U67 S;  2PIC A;  3PIP S;  1QRT A;  3KW2 A;  2PNW A;  5GAE W;  3J7Z V;  3ONP A;  3NK6 A;  1ZJR A;  4YQG A;  4L69 A;  5GAG W;  4YQ4 A;  4X3L A;  5GM8 A;  4H3Z A;  4IOC S;  4YPX A;  3CZB A;  3AII A;  3KY7 A;  4XBO A;  2NWA A;  1O0C A;  1NS5 A;  2PI8 A;  3N4K A;  2O3A A;  1ZJW A;  2AE0 X;  4IG6 A;  4YQ9 A;  3AXZ A;  4YVG A;  4PZK A;  4YQ3 A;  5DM6 S;  2I6D A;  1P9P A;  4KGN A;  2QWV A;  3BBD A;  5BNZ A;  4WFB S;  5D9F A;  2YY8 A;  4YQI A;  1UAL A;  3OIN A;  4RG1 A;  1V6Z A;  4MCD A;  5GAD W;  4MCC A;  4YQ5 A;  2EGW A;  3NK7 A;  3AI9 X;  4YQJ A;  3BBH A;  3W2W B;  1X7O A;  1V2X A; 
#chains in the Genus database with same CATH homology
 4CND A;  1J85 A;  4YQL A;  4YQP A;  2QMM A;  3KNU A;  1TO0 A;  4YQ7 A;  2V3J A;  3N4J A;  3BBE A;  4CNG A;  1O6D A;  3ILK A;  4YQ1 A;  4JWH A;  4YQ0 A;  1Z85 A;  3O7B A;  4CNE A;  4YVH A;  1IPA A;  2EGV A;  1K3R A;  1UAK A;  3KTY A;  4J3C A;  1X7P A;  2HA8 A;  4YQB A;  1VHK A;  3IEF A;  1UAM A;  5GMC A;  4YQS A;  3AIA A;  4FMW A;  4YQR A;  5GMB A;  4FAK A;  1NXZ A;  4YQT A;  4E8B A;  4YVK A;  4YPZ A;  1VH0 A;  4JAL A;  4YPY A;  1MXI A;  1UAJ A;  2CX8 A;  4YQQ A;  4MCB A;  5CO4 A;  4YQN A;  4YPW A;  4YQ2 A;  1GZ0 A;  3L8U A;  4YQA A;  4YQC A;  2Z0Y A;  3GYQ A;  3DCM X;  4JAK A;  4JWF A;  5FAI A;  4YVI A;  3OIJ A;  3QUV A;  4H3Y A;  4YQ8 A;  3IC6 A;  4CNF A;  3OII A;  4JWG A;  2V3K A;  4YQD A;  4YVJ A;  1VHY A;  4KDZ A;  4YQK A;  4YQO A;  4X3M A;  4JWJ A;  1OY5 A;  4YQ6 A;  3E5Y A;  3KW2 A;  3ONP A;  3NK6 A;  1ZJR A;  4YQG A;  4L69 A;  4YQ4 A;  4X3L A;  5GM8 A;  4H3Z A;  4YPX A;  3KY7 A;  4XBO A;  2NWA A;  1NS5 A;  3N4K A;  2O3A A;  4IG6 A;  4YQ9 A;  3AXZ A;  4YVG A;  4PZK A;  4YQ3 A;  2I6D A;  1P9P A;  4KGN A;  2QWV A;  3BBD A;  5D9F A;  2YY8 A;  4YQI A;  1UAL A;  3OIN A;  4RG1 A;  1V6Z A;  4MCD A;  4MCC A;  4YQ5 A;  2EGW A;  3NK7 A;  3AI9 X;  4YQJ A;  3BBH A;  1X7O A;  1V2X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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