2IUCB

Structure of alkaline phosphatase from the antarctic bacterium tab5
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
Knots found
sequence length
346
structure length
342
Chain Sequence
QLKTPKNVILLISDGAGLSQISSTFYFKSGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNSIKTGVVATSSITHATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTSRSDSKDVLAILKGNQFTINTTGLTDFSSIASNRKMGFLLADEAMPTMEKGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKSDGNTLVIVTSDHETGGFTLAAKSNKSEYSDYTEIGPTFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
pubmed doi rcsb
molecule tags Hydrolase
source organism Antarctic bacterium tab5
molecule keywords ALKALINE PHOSPHATASE
total genus 125
structure length 342
sequence length 346
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2iucB00
1P49A 5L0EA 1AJAA 2XRGA 1AJBA 4MHXA 3WBHA 4FDJA 2IUCB 1ED8A 1Y6VA 2W8DA 3TX0A 3M8YA 3UNYA 4QAXA 3BDFA 4LRCA 3NKQA 4KAYA 3Q3QA 3NKMA 4LR2A 4TN0A 4CYRA 1AJDA 4KJGA 2IUCA 3SZZA 5LIAA 3OT9A 4UPKA 3WAVA 2D1GA 1E1ZP 4ZG9A 1KH9A 1ZEFA 2W5XA 2W5TA 1ALKA 1E33P 5EGEA 5L0BA 4FDIA 3NKOA 1E2SP 3IGYB 4GTZA 1URBA 1KHJA 2GLQA 2IFYA 4CYSA 2W5VA 4LRDA 1EQJA 4LRBA 4UORA 5GOVA 1EI6A 2VQRA 5EGHA 4LRAA 3CMRA 5LQQA 2X98A 3BDHA 3MK2A 1URAA 5TJ3A 1EW2A 2ANHA 1ELZA 5IJSA 3M7VA 4CXSA 4NWJA 5INHA 1Y7AA 1ALHA 1EW9A 1K7HA 2GSOA 3MK1A 4GTXA 4UOOA 4MY4A 3T00A 2W5QA 2W5SA 1EJJA 4NWXA 5IJQA 1AUKA 3ED4A 4UPLA 1EW8A 4GTYA 3TWZA 1ALIA 4UPHA 4YR1A 3DYCA 3KD8A 1B8JA 1KH5A 4LREA 3A52A 1ED9A 4LRFA 3NKRA 1HQAA 3T01A 2XR9A 3MK0A 4ZG6A 5DLWA 1AJCA 2W5RA 1KHLA 3NKPA 2QZUA 2ZKTA 3UO0A 5GRRA 1N2LA 5LRNA 4N7TA 4CXUA 4CXKA 4LR7A 3NVLA 3NKNA 5LRMA 2G9YA 3UN3A 2GA3A 2GSNA 4LQYA 3WAXA 1ELYA 1ALJA 1FSUA 1KH4A 1N2KA 4UOPA 1SHQA 5AJ9A 1O98A 3WAYA 4B56A 4KAVA 1KH7A 5C66A 3UN2A 2GSUA 4UPIA 1O99A 2RH6A 4LR8A 3UN5A 1KHKA 3M8ZA 2W5WA 3B5QA 4KM4A 1SHNA 3T02A 4KJDA 3DPCA 1HDHA 1ANIA 4ZG7A 3M8WA 1ELXA 4GTWA 1ZEDA 5DLVA 1ANJA 3BDGB 5K4PA 4LR9A 5HRTA 1E3CP 2W8SA 1KHNA 1HJKA 3WAWA 5KXAA 1ZEBA 3IGZB 4MIVA 3SZYA 3LXQA 3TG0A 4ZGAA 3IDDA 3BDGA 3E2DA 5L0KA 5DLTA
chains in the Genus database with same CATH superfamily
1P49A 5L0EA 1AJAA 2XRGA 1AJBA 4MHXA 3WBHA 4FDJA 2IUCB 1ED8A 1Y6VA 2W8DA 3TX0A 3M8YA 3UNYA 4QAXA 3BDFA 4LRCA 3NKQA 4KAYA 3Q3QA 3NKMA 4LR2A 4TN0A 4CYRA 1AJDA 4KJGA 2IUCA 3SZZA 5LIAA 3OT9A 4UPKA 3WAVA 2D1GA 1E1ZP 4ZG9A 1KH9A 1ZEFA 2W5XA 2W5TA 1ALKA 1E33P 5EGEA 5L0BA 4FDIA 3NKOA 1E2SP 3IGYB 4GTZA 1URBA 1KHJA 2GLQA 2IFYA 4CYSA 2W5VA 4LRDA 1EQJA 4LRBA 4UORA 5GOVA 1EI6A 2VQRA 5EGHA 4LRAA 3CMRA 5LQQA 2X98A 3BDHA 3MK2A 1URAA 5TJ3A 1EW2A 2ANHA 1ELZA 5IJSA 3M7VA 4CXSA 4NWJA 5INHA 1Y7AA 1ALHA 1EW9A 1K7HA 2GSOA 3MK1A 4GTXA 4UOOA 4MY4A 3T00A 2W5QA 2W5SA 1EJJA 4NWXA 5IJQA 1AUKA 3ED4A 4UPLA 1EW8A 4GTYA 3TWZA 1ALIA 4UPHA 4YR1A 3DYCA 3KD8A 1B8JA 1KH5A 4LREA 3A52A 1ED9A 4LRFA 3NKRA 1HQAA 3T01A 2XR9A 3MK0A 4ZG6A 5DLWA 1AJCA 2W5RA 1KHLA 3NKPA 2QZUA 2ZKTA 3UO0A 5GRRA 1N2LA 5LRNA 4N7TA 4CXUA 4CXKA 4LR7A 3NVLA 3NKNA 5LRMA 2G9YA 3UN3A 2GA3A 2GSNA 4LQYA 3WAXA 1ELYA 1ALJA 1FSUA 1KH4A 1N2KA 4UOPA 1SHQA 5AJ9A 1O98A 3WAYA 4B56A 4KAVA 1KH7A 5C66A 3UN2A 2GSUA 4UPIA 1O99A 2RH6A 4LR8A 3UN5A 1KHKA 3M8ZA 2W5WA 3B5QA 4KM4A 1SHNA 3T02A 4KJDA 3DPCA 1HDHA 1ANIA 4ZG7A 3M8WA 1ELXA 4GTWA 1ZEDA 5DLVA 1ANJA 3BDGB 5K4PA 4LR9A 5HRTA 1E3CP 2W8SA 1KHNA 1HJKA 3WAWA 5KXAA 1ZEBA 3IGZB 4MIVA 3SZYA 3LXQA 3TG0A 4ZGAA 3IDDA 3BDGA 3E2DA 5L0KA 5DLTA
chains in the Genus database with same CATH topology
1P49A 5L0EA 1AJAA 2XRGA 1AJBA 4MHXA 3WBHA 4FDJA 2IUCB 1ED8A 1Y6VA 2W8DA 3TX0A 3M8YA 3UNYA 4QAXA 3BDFA 4LRCA 3NKQA 4KAYA 3Q3QA 3NKMA 4LR2A 4TN0A 4CYRA 1AJDA 4KJGA 2IUCA 3SZZA 5LIAA 3OT9A 4UPKA 3WAVA 2D1GA 1E1ZP 4ZG9A 1KH9A 1ZEFA 2W5XA 2W5TA 1ALKA 1E33P 5EGEA 5L0BA 4FDIA 3NKOA 1E2SP 3IGYB 4GTZA 1URBA 1KHJA 2GLQA 2IFYA 4CYSA 2W5VA 4LRDA 1EQJA 4LRBA 4UORA 5GOVA 1EI6A 2VQRA 5EGHA 4LRAA 3CMRA 5LQQA 2X98A 3BDHA 3MK2A 1URAA 5TJ3A 1EW2A 2ANHA 1ELZA 5IJSA 3M7VA 4CXSA 4NWJA 5INHA 1Y7AA 1ALHA 1EW9A 1K7HA 2GSOA 3MK1A 4GTXA 4UOOA 4MY4A 3T00A 2W5QA 2W5SA 1EJJA 4NWXA 5IJQA 1AUKA 3ED4A 4UPLA 1EW8A 4GTYA 3TWZA 1ALIA 4UPHA 4YR1A 3DYCA 3KD8A 1B8JA 1KH5A 4LREA 3A52A 1ED9A 4LRFA 3NKRA 1HQAA 3T01A 2XR9A 3MK0A 4ZG6A 5DLWA 1AJCA 2W5RA 1KHLA 3NKPA 2QZUA 2ZKTA 3UO0A 5GRRA 1N2LA 5LRNA 4N7TA 4CXUA 4CXKA 4LR7A 3NVLA 3NKNA 5LRMA 2G9YA 3UN3A 2GA3A 2GSNA 4LQYA 3WAXA 1ELYA 1ALJA 1FSUA 1KH4A 1N2KA 4UOPA 1SHQA 5AJ9A 1O98A 3WAYA 4B56A 4KAVA 1KH7A 5C66A 3UN2A 2GSUA 4UPIA 1O99A 2RH6A 4LR8A 3UN5A 1KHKA 3M8ZA 2W5WA 3B5QA 4KM4A 1SHNA 3T02A 4KJDA 3DPCA 1HDHA 1ANIA 4ZG7A 3M8WA 1ELXA 4GTWA 1ZEDA 5DLVA 1ANJA 3BDGB 5K4PA 4LR9A 5HRTA 1E3CP 2W8SA 1KHNA 1HJKA 3WAWA 5KXAA 1ZEBA 3IGZB 4MIVA 3SZYA 3LXQA 3TG0A 4ZGAA 3IDDA 3BDGA 3E2DA 5L0KA 5DLTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P49 A;  5L0E A;  1AJA A;  2XRG A;  1AJB A;  4MHX A;  3WBH A;  4FDJ A;  2IUC B;  1ED8 A;  1Y6V A;  2W8D A;  3TX0 A;  3M8Y A;  3UNY A;  4QAX A;  3BDF A;  4LRC A;  3NKQ A;  4KAY A;  3Q3Q A;  3NKM A;  4LR2 A;  4TN0 A;  4CYR A;  1AJD A;  4KJG A;  2IUC A;  3SZZ A;  5LIA A;  3OT9 A;  4UPK A;  3WAV A;  2D1G A;  1E1Z P;  4ZG9 A;  1KH9 A;  1ZEF A;  2W5X A;  2W5T A;  1ALK A;  1E33 P;  5EGE A;  5L0B A;  4FDI A;  3NKO A;  1E2S P;  3IGY B;  4GTZ A;  1URB A;  1KHJ A;  2GLQ A;  2IFY A;  4CYS A;  2W5V A;  4LRD A;  1EQJ A;  4LRB A;  4UOR A;  5GOV A;  1EI6 A;  2VQR A;  5EGH A;  4LRA A;  3CMR A;  5LQQ A;  2X98 A;  3BDH A;  3MK2 A;  1URA A;  5TJ3 A;  1EW2 A;  2ANH A;  1ELZ A;  5IJS A;  3M7V A;  4CXS A;  4NWJ A;  5INH A;  1Y7A A;  1ALH A;  1EW9 A;  1K7H A;  2GSO A;  3MK1 A;  4GTX A;  4UOO A;  4MY4 A;  3T00 A;  2W5Q A;  2W5S A;  1EJJ A;  4NWX A;  5IJQ A;  1AUK A;  3ED4 A;  4UPL A;  1EW8 A;  4GTY A;  3TWZ A;  1ALI A;  4UPH A;  4YR1 A;  3DYC A;  3KD8 A;  1B8J A;  1KH5 A;  4LRE A;  3A52 A;  1ED9 A;  4LRF A;  3NKR A;  1HQA A;  3T01 A;  2XR9 A;  3MK0 A;  4ZG6 A;  5DLW A;  1AJC A;  2W5R A;  1KHL A;  3NKP A;  2QZU A;  2ZKT A;  3UO0 A;  5GRR A;  1N2L A;  5LRN A;  4N7T A;  4CXU A;  4CXK A;  4LR7 A;  3NVL A;  3NKN A;  5LRM A;  2G9Y A;  3UN3 A;  2GA3 A;  2GSN A;  4LQY A;  3WAX A;  1ELY A;  1ALJ A;  1FSU A;  1KH4 A;  1N2K A;  4UOP A;  1SHQ A;  5AJ9 A;  1O98 A;  3WAY A;  4B56 A;  4KAV A;  1KH7 A;  5C66 A;  3UN2 A;  2GSU A;  4UPI A;  1O99 A;  2RH6 A;  4LR8 A;  3UN5 A;  1KHK A;  3M8Z A;  2W5W A;  3B5Q A;  4KM4 A;  1SHN A;  3T02 A;  4KJD A;  3DPC A;  1HDH A;  1ANI A;  4ZG7 A;  3M8W A;  1ELX A;  4GTW A;  1ZED A;  5DLV A;  1ANJ A;  3BDG B;  5K4P A;  4LR9 A;  5HRT A;  1E3C P;  2W8S A;  1KHN A;  1HJK A;  3WAW A;  5KXA A;  1ZEB A;  3IGZ B;  4MIV A;  3SZY A;  3LXQ A;  3TG0 A;  4ZGA A;  3IDD A;  3BDG A;  3E2D A;  5L0K A;  5DLT A; 
#chains in the Genus database with same CATH topology
 1P49 A;  5L0E A;  1AJA A;  2XRG A;  1AJB A;  4MHX A;  3WBH A;  4FDJ A;  2IUC B;  1ED8 A;  1Y6V A;  2W8D A;  3TX0 A;  3M8Y A;  3UNY A;  4QAX A;  3BDF A;  4LRC A;  3NKQ A;  4KAY A;  3Q3Q A;  3NKM A;  4LR2 A;  4TN0 A;  4CYR A;  1AJD A;  4KJG A;  2IUC A;  3SZZ A;  5LIA A;  3OT9 A;  4UPK A;  3WAV A;  2D1G A;  1E1Z P;  4ZG9 A;  1KH9 A;  1ZEF A;  2W5X A;  2W5T A;  1ALK A;  1E33 P;  5EGE A;  5L0B A;  4FDI A;  3NKO A;  1E2S P;  3IGY B;  4GTZ A;  1URB A;  1KHJ A;  2GLQ A;  2IFY A;  4CYS A;  2W5V A;  4LRD A;  1EQJ A;  4LRB A;  4UOR A;  5GOV A;  1EI6 A;  2VQR A;  5EGH A;  4LRA A;  3CMR A;  5LQQ A;  2X98 A;  3BDH A;  3MK2 A;  1URA A;  5TJ3 A;  1EW2 A;  2ANH A;  1ELZ A;  5IJS A;  3M7V A;  4CXS A;  4NWJ A;  5INH A;  1Y7A A;  1ALH A;  1EW9 A;  1K7H A;  2GSO A;  3MK1 A;  4GTX A;  4UOO A;  4MY4 A;  3T00 A;  2W5Q A;  2W5S A;  1EJJ A;  4NWX A;  5IJQ A;  1AUK A;  3ED4 A;  4UPL A;  1EW8 A;  4GTY A;  3TWZ A;  1ALI A;  4UPH A;  4YR1 A;  3DYC A;  3KD8 A;  1B8J A;  1KH5 A;  4LRE A;  3A52 A;  1ED9 A;  4LRF A;  3NKR A;  1HQA A;  3T01 A;  2XR9 A;  3MK0 A;  4ZG6 A;  5DLW A;  1AJC A;  2W5R A;  1KHL A;  3NKP A;  2QZU A;  2ZKT A;  3UO0 A;  5GRR A;  1N2L A;  5LRN A;  4N7T A;  4CXU A;  4CXK A;  4LR7 A;  3NVL A;  3NKN A;  5LRM A;  2G9Y A;  3UN3 A;  2GA3 A;  2GSN A;  4LQY A;  3WAX A;  1ELY A;  1ALJ A;  1FSU A;  1KH4 A;  1N2K A;  4UOP A;  1SHQ A;  5AJ9 A;  1O98 A;  3WAY A;  4B56 A;  4KAV A;  1KH7 A;  5C66 A;  3UN2 A;  2GSU A;  4UPI A;  1O99 A;  2RH6 A;  4LR8 A;  3UN5 A;  1KHK A;  3M8Z A;  2W5W A;  3B5Q A;  4KM4 A;  1SHN A;  3T02 A;  4KJD A;  3DPC A;  1HDH A;  1ANI A;  4ZG7 A;  3M8W A;  1ELX A;  4GTW A;  1ZED A;  5DLV A;  1ANJ A;  3BDG B;  5K4P A;  4LR9 A;  5HRT A;  1E3C P;  2W8S A;  1KHN A;  1HJK A;  3WAW A;  5KXA A;  1ZEB A;  3IGZ B;  4MIV A;  3SZY A;  3LXQ A;  3TG0 A;  4ZGA A;  3IDD A;  3BDG A;  3E2D A;  5L0K A;  5DLT A; 
#chains in the Genus database with same CATH homology
 1P49 A;  5L0E A;  1AJA A;  2XRG A;  1AJB A;  4MHX A;  3WBH A;  4FDJ A;  2IUC B;  1ED8 A;  1Y6V A;  2W8D A;  3TX0 A;  3M8Y A;  3UNY A;  4QAX A;  3BDF A;  4LRC A;  3NKQ A;  4KAY A;  3Q3Q A;  3NKM A;  4LR2 A;  4TN0 A;  4CYR A;  1AJD A;  4KJG A;  2IUC A;  3SZZ A;  5LIA A;  3OT9 A;  4UPK A;  3WAV A;  2D1G A;  1E1Z P;  4ZG9 A;  1KH9 A;  1ZEF A;  2W5X A;  2W5T A;  1ALK A;  1E33 P;  5EGE A;  5L0B A;  4FDI A;  3NKO A;  1E2S P;  3IGY B;  4GTZ A;  1URB A;  1KHJ A;  2GLQ A;  2IFY A;  4CYS A;  2W5V A;  4LRD A;  1EQJ A;  4LRB A;  4UOR A;  5GOV A;  1EI6 A;  2VQR A;  5EGH A;  4LRA A;  3CMR A;  5LQQ A;  2X98 A;  3BDH A;  3MK2 A;  1URA A;  5TJ3 A;  1EW2 A;  2ANH A;  1ELZ A;  5IJS A;  3M7V A;  4CXS A;  4NWJ A;  5INH A;  1Y7A A;  1ALH A;  1EW9 A;  1K7H A;  2GSO A;  3MK1 A;  4GTX A;  4UOO A;  4MY4 A;  3T00 A;  2W5Q A;  2W5S A;  1EJJ A;  4NWX A;  5IJQ A;  1AUK A;  3ED4 A;  4UPL A;  1EW8 A;  4GTY A;  3TWZ A;  1ALI A;  4UPH A;  4YR1 A;  3DYC A;  3KD8 A;  1B8J A;  1KH5 A;  4LRE A;  3A52 A;  1ED9 A;  4LRF A;  3NKR A;  1HQA A;  3T01 A;  2XR9 A;  3MK0 A;  4ZG6 A;  5DLW A;  1AJC A;  2W5R A;  1KHL A;  3NKP A;  2QZU A;  2ZKT A;  3UO0 A;  5GRR A;  1N2L A;  5LRN A;  4N7T A;  4CXU A;  4CXK A;  4LR7 A;  3NVL A;  3NKN A;  5LRM A;  2G9Y A;  3UN3 A;  2GA3 A;  2GSN A;  4LQY A;  3WAX A;  1ELY A;  1ALJ A;  1FSU A;  1KH4 A;  1N2K A;  4UOP A;  1SHQ A;  5AJ9 A;  1O98 A;  3WAY A;  4B56 A;  4KAV A;  1KH7 A;  5C66 A;  3UN2 A;  2GSU A;  4UPI A;  1O99 A;  2RH6 A;  4LR8 A;  3UN5 A;  1KHK A;  3M8Z A;  2W5W A;  3B5Q A;  4KM4 A;  1SHN A;  3T02 A;  4KJD A;  3DPC A;  1HDH A;  1ANI A;  4ZG7 A;  3M8W A;  1ELX A;  4GTW A;  1ZED A;  5DLV A;  1ANJ A;  3BDG B;  5K4P A;  4LR9 A;  5HRT A;  1E3C P;  2W8S A;  1KHN A;  1HJK A;  3WAW A;  5KXA A;  1ZEB A;  3IGZ B;  4MIV A;  3SZY A;  3LXQ A;  3TG0 A;  4ZGA A;  3IDD A;  3BDG A;  3E2D A;  5L0K A;  5DLT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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