2IUCA

Structure of alkaline phosphatase from the antarctic bacterium tab5
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
Knots found
sequence length
344
structure length
340
Chain Sequence
KTPKNVILLISDGAGLSQISSTFYFKEGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNNIKTGVVATSSITHATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTSRKDKKDVLAILKGNQFTINTTGLTDFSSIASNRKMGFLLADEAMPTMESGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKKDGNTLVIVTSDHETGGFTLAAKKNKREYSDYTSIGPSFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
pubmed doi rcsb
molecule keywords ALKALINE PHOSPHATASE
molecule tags Hydrolase
source organism Antarctic bacterium tab5
total genus 133
structure length 340
sequence length 344
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2iucA00
1URAA 4GTWA 4KAVA 4UOPA 5DLVA 4FDJA 2XR9A 1E3CP 1ANIA 4LR2A 2GA3A 1N2LA 4LRDA 4NWJA 4MY4A 5K4PA 4NWXA 3MK2A 4LQYA 4B56A 1O99A 1E33P 4LR8A 2ANHA 4KAYA 3SZYA 4CXKA 1ZEFA 4KJDA 3ED4A 2W5WA 3WAYA 3BDGB 1ELZA 1EW2A 4LR9A 3NKQA 1O98A 3KD8A 1ED9A 1FSUA 4UORA 3TG0A 3UN5A 4ZG7A 1HDHA 2W5VA 5EGEA 5GRRA 5L0KA 5TJ3A 1KH5A 1AJBA 1ZEDA 4ZG9A 3WBHA 1Y7AA 2G9YA 2W5QA 5DLWA 4ZG6A 1K7HA 3BDGA 1EQJA 3WAWA 4UPHA 5HRTA 3T00A 4CXUA 2IUCA 3OT9A 2IFYA 3DPCA 1ALJA 3IDDA 3LXQA 1KHNA 4CYSA 1URBA 5IJQA 2QZUA 3T02A 1ALIA 2GSNA 1ELXA 4LRBA 5LIAA 1B8JA 5L0BA 1ZEBA 1AUKA 3A52A 1ALKA 1ANJA 1SHNA 3NKNA 2W5XA 1EI6A 1KHLA 1ED8A 4GTZA 4LREA 4UPIA 3B5QA 4ZGAA 3T01A 3NKMA 3BDHA 2XRGA 3M8YA 3MK0A 4LRCA 4LRFA 5INHA 1EW9A 2W8SA 3CMRA 3M8ZA 5DLTA 5GOVA 3NVLA 1KH4A 4KM4A 4UPKA 2RH6A 1N2KA 4GTYA 4UOOA 3Q3QA 1SHQA 2W8DA 1E2SP 2W5RA 3WAXA 4N7TA 1HQAA 3MK1A 2VQRA 4LR7A 3DYCA 5C66A 5L0EA 3NKRA 5EGHA 5KXAA 4YR1A 5LRMA 3UNYA 3IGZB 4GTXA 1KH9A 5IJSA 2W5SA 2ZKTA 1P49A 4QAXA 1AJAA 2GLQA 2D1GA 3WAVA 3UN3A 3M7VA 4CYRA 3IGYB 4FDIA 3M8WA 1ELYA 3TX0A 1HJKA 1AJDA 1KHKA 2GSUA 2W5TA 4UPLA 1EW8A 4CXSA 2X98A 1KH7A 3NKOA 3SZZA 4MHXA 3NKPA 1KHJA 5LQQA 3E2DA 1AJCA 5LRNA 5AJ9A 3UN2A 2GSOA 2IUCB 4LRAA 3BDFA 3TWZA 3UO0A 1E1ZP 1Y6VA 4KJGA 4MIVA 1EJJA 4TN0A 1ALHA
chains in the Genus database with same CATH superfamily
1URAA 4GTWA 4KAVA 4UOPA 5DLVA 4FDJA 2XR9A 1E3CP 1ANIA 4LR2A 2GA3A 1N2LA 4LRDA 4NWJA 4MY4A 5K4PA 4NWXA 3MK2A 4LQYA 4B56A 1O99A 1E33P 4LR8A 2ANHA 4KAYA 3SZYA 4CXKA 1ZEFA 4KJDA 3ED4A 2W5WA 3WAYA 3BDGB 1ELZA 1EW2A 4LR9A 3NKQA 1O98A 3KD8A 1ED9A 1FSUA 4UORA 3TG0A 3UN5A 4ZG7A 1HDHA 2W5VA 5EGEA 5GRRA 5L0KA 5TJ3A 1KH5A 1AJBA 1ZEDA 4ZG9A 3WBHA 1Y7AA 2G9YA 2W5QA 5DLWA 4ZG6A 1K7HA 3BDGA 1EQJA 3WAWA 4UPHA 5HRTA 3T00A 4CXUA 2IUCA 3OT9A 2IFYA 3DPCA 1ALJA 3IDDA 3LXQA 1KHNA 4CYSA 1URBA 5IJQA 2QZUA 3T02A 1ALIA 2GSNA 1ELXA 4LRBA 5LIAA 1B8JA 5L0BA 1ZEBA 1AUKA 3A52A 1ALKA 1ANJA 1SHNA 3NKNA 2W5XA 1EI6A 1KHLA 1ED8A 4GTZA 4LREA 4UPIA 3B5QA 4ZGAA 3T01A 3NKMA 3BDHA 2XRGA 3M8YA 3MK0A 4LRCA 4LRFA 5INHA 1EW9A 2W8SA 3CMRA 3M8ZA 5DLTA 5GOVA 3NVLA 1KH4A 4KM4A 4UPKA 2RH6A 1N2KA 4GTYA 4UOOA 3Q3QA 1SHQA 2W8DA 1E2SP 2W5RA 3WAXA 4N7TA 1HQAA 3MK1A 2VQRA 4LR7A 3DYCA 5C66A 5L0EA 3NKRA 5EGHA 5KXAA 4YR1A 5LRMA 3UNYA 3IGZB 4GTXA 1KH9A 5IJSA 2W5SA 2ZKTA 1P49A 4QAXA 1AJAA 2GLQA 2D1GA 3WAVA 3UN3A 3M7VA 4CYRA 3IGYB 4FDIA 3M8WA 1ELYA 3TX0A 1HJKA 1AJDA 1KHKA 2GSUA 2W5TA 4UPLA 1EW8A 4CXSA 2X98A 1KH7A 3NKOA 3SZZA 4MHXA 3NKPA 1KHJA 5LQQA 3E2DA 1AJCA 5LRNA 5AJ9A 3UN2A 2GSOA 2IUCB 4LRAA 3BDFA 3TWZA 3UO0A 1E1ZP 1Y6VA 4KJGA 4MIVA 1EJJA 4TN0A 1ALHA
chains in the Genus database with same CATH topology
1URAA 4GTWA 4KAVA 4UOPA 5DLVA 4FDJA 2XR9A 1E3CP 1ANIA 4LR2A 2GA3A 1N2LA 4LRDA 4NWJA 4MY4A 5K4PA 4NWXA 3MK2A 4LQYA 4B56A 1O99A 1E33P 4LR8A 2ANHA 4KAYA 3SZYA 4CXKA 1ZEFA 4KJDA 3ED4A 2W5WA 3WAYA 3BDGB 1ELZA 1EW2A 4LR9A 3NKQA 1O98A 3KD8A 1ED9A 1FSUA 4UORA 3TG0A 3UN5A 4ZG7A 1HDHA 2W5VA 5EGEA 5GRRA 5L0KA 5TJ3A 1KH5A 1AJBA 1ZEDA 4ZG9A 3WBHA 1Y7AA 2G9YA 2W5QA 5DLWA 4ZG6A 1K7HA 3BDGA 1EQJA 3WAWA 4UPHA 5HRTA 3T00A 4CXUA 2IUCA 3OT9A 2IFYA 3DPCA 1ALJA 3IDDA 3LXQA 1KHNA 4CYSA 1URBA 5IJQA 2QZUA 3T02A 1ALIA 2GSNA 1ELXA 4LRBA 5LIAA 1B8JA 5L0BA 1ZEBA 1AUKA 3A52A 1ALKA 1ANJA 1SHNA 3NKNA 2W5XA 1EI6A 1KHLA 1ED8A 4GTZA 4LREA 4UPIA 3B5QA 4ZGAA 3T01A 3NKMA 3BDHA 2XRGA 3M8YA 3MK0A 4LRCA 4LRFA 5INHA 1EW9A 2W8SA 3CMRA 3M8ZA 5DLTA 5GOVA 3NVLA 1KH4A 4KM4A 4UPKA 2RH6A 1N2KA 4GTYA 4UOOA 3Q3QA 1SHQA 2W8DA 1E2SP 2W5RA 3WAXA 4N7TA 1HQAA 3MK1A 2VQRA 4LR7A 3DYCA 5C66A 5L0EA 3NKRA 5EGHA 5KXAA 4YR1A 5LRMA 3UNYA 3IGZB 4GTXA 1KH9A 5IJSA 2W5SA 2ZKTA 1P49A 4QAXA 1AJAA 2GLQA 2D1GA 3WAVA 3UN3A 3M7VA 4CYRA 3IGYB 4FDIA 3M8WA 1ELYA 3TX0A 1HJKA 1AJDA 1KHKA 2GSUA 2W5TA 4UPLA 1EW8A 4CXSA 2X98A 1KH7A 3NKOA 3SZZA 4MHXA 3NKPA 1KHJA 5LQQA 3E2DA 1AJCA 5LRNA 5AJ9A 3UN2A 2GSOA 2IUCB 4LRAA 3BDFA 3TWZA 3UO0A 1E1ZP 1Y6VA 4KJGA 4MIVA 1EJJA 4TN0A 1ALHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1URA A;  4GTW A;  4KAV A;  4UOP A;  5DLV A;  4FDJ A;  2XR9 A;  1E3C P;  1ANI A;  4LR2 A;  2GA3 A;  1N2L A;  4LRD A;  4NWJ A;  4MY4 A;  5K4P A;  4NWX A;  3MK2 A;  4LQY A;  4B56 A;  1O99 A;  1E33 P;  4LR8 A;  2ANH A;  4KAY A;  3SZY A;  4CXK A;  1ZEF A;  4KJD A;  3ED4 A;  2W5W A;  3WAY A;  3BDG B;  1ELZ A;  1EW2 A;  4LR9 A;  3NKQ A;  1O98 A;  3KD8 A;  1ED9 A;  1FSU A;  4UOR A;  3TG0 A;  3UN5 A;  4ZG7 A;  1HDH A;  2W5V A;  5EGE A;  5GRR A;  5L0K A;  5TJ3 A;  1KH5 A;  1AJB A;  1ZED A;  4ZG9 A;  3WBH A;  1Y7A A;  2G9Y A;  2W5Q A;  5DLW A;  4ZG6 A;  1K7H A;  3BDG A;  1EQJ A;  3WAW A;  4UPH A;  5HRT A;  3T00 A;  4CXU A;  2IUC A;  3OT9 A;  2IFY A;  3DPC A;  1ALJ A;  3IDD A;  3LXQ A;  1KHN A;  4CYS A;  1URB A;  5IJQ A;  2QZU A;  3T02 A;  1ALI A;  2GSN A;  1ELX A;  4LRB A;  5LIA A;  1B8J A;  5L0B A;  1ZEB A;  1AUK A;  3A52 A;  1ALK A;  1ANJ A;  1SHN A;  3NKN A;  2W5X A;  1EI6 A;  1KHL A;  1ED8 A;  4GTZ A;  4LRE A;  4UPI A;  3B5Q A;  4ZGA A;  3T01 A;  3NKM A;  3BDH A;  2XRG A;  3M8Y A;  3MK0 A;  4LRC A;  4LRF A;  5INH A;  1EW9 A;  2W8S A;  3CMR A;  3M8Z A;  5DLT A;  5GOV A;  3NVL A;  1KH4 A;  4KM4 A;  4UPK A;  2RH6 A;  1N2K A;  4GTY A;  4UOO A;  3Q3Q A;  1SHQ A;  2W8D A;  1E2S P;  2W5R A;  3WAX A;  4N7T A;  1HQA A;  3MK1 A;  2VQR A;  4LR7 A;  3DYC A;  5C66 A;  5L0E A;  3NKR A;  5EGH A;  5KXA A;  4YR1 A;  5LRM A;  3UNY A;  3IGZ B;  4GTX A;  1KH9 A;  5IJS A;  2W5S A;  2ZKT A;  1P49 A;  4QAX A;  1AJA A;  2GLQ A;  2D1G A;  3WAV A;  3UN3 A;  3M7V A;  4CYR A;  3IGY B;  4FDI A;  3M8W A;  1ELY A;  3TX0 A;  1HJK A;  1AJD A;  1KHK A;  2GSU A;  2W5T A;  4UPL A;  1EW8 A;  4CXS A;  2X98 A;  1KH7 A;  3NKO A;  3SZZ A;  4MHX A;  3NKP A;  1KHJ A;  5LQQ A;  3E2D A;  1AJC A;  5LRN A;  5AJ9 A;  3UN2 A;  2GSO A;  2IUC B;  4LRA A;  3BDF A;  3TWZ A;  3UO0 A;  1E1Z P;  1Y6V A;  4KJG A;  4MIV A;  1EJJ A;  4TN0 A;  1ALH A; 
#chains in the Genus database with same CATH topology
 1URA A;  4GTW A;  4KAV A;  4UOP A;  5DLV A;  4FDJ A;  2XR9 A;  1E3C P;  1ANI A;  4LR2 A;  2GA3 A;  1N2L A;  4LRD A;  4NWJ A;  4MY4 A;  5K4P A;  4NWX A;  3MK2 A;  4LQY A;  4B56 A;  1O99 A;  1E33 P;  4LR8 A;  2ANH A;  4KAY A;  3SZY A;  4CXK A;  1ZEF A;  4KJD A;  3ED4 A;  2W5W A;  3WAY A;  3BDG B;  1ELZ A;  1EW2 A;  4LR9 A;  3NKQ A;  1O98 A;  3KD8 A;  1ED9 A;  1FSU A;  4UOR A;  3TG0 A;  3UN5 A;  4ZG7 A;  1HDH A;  2W5V A;  5EGE A;  5GRR A;  5L0K A;  5TJ3 A;  1KH5 A;  1AJB A;  1ZED A;  4ZG9 A;  3WBH A;  1Y7A A;  2G9Y A;  2W5Q A;  5DLW A;  4ZG6 A;  1K7H A;  3BDG A;  1EQJ A;  3WAW A;  4UPH A;  5HRT A;  3T00 A;  4CXU A;  2IUC A;  3OT9 A;  2IFY A;  3DPC A;  1ALJ A;  3IDD A;  3LXQ A;  1KHN A;  4CYS A;  1URB A;  5IJQ A;  2QZU A;  3T02 A;  1ALI A;  2GSN A;  1ELX A;  4LRB A;  5LIA A;  1B8J A;  5L0B A;  1ZEB A;  1AUK A;  3A52 A;  1ALK A;  1ANJ A;  1SHN A;  3NKN A;  2W5X A;  1EI6 A;  1KHL A;  1ED8 A;  4GTZ A;  4LRE A;  4UPI A;  3B5Q A;  4ZGA A;  3T01 A;  3NKM A;  3BDH A;  2XRG A;  3M8Y A;  3MK0 A;  4LRC A;  4LRF A;  5INH A;  1EW9 A;  2W8S A;  3CMR A;  3M8Z A;  5DLT A;  5GOV A;  3NVL A;  1KH4 A;  4KM4 A;  4UPK A;  2RH6 A;  1N2K A;  4GTY A;  4UOO A;  3Q3Q A;  1SHQ A;  2W8D A;  1E2S P;  2W5R A;  3WAX A;  4N7T A;  1HQA A;  3MK1 A;  2VQR A;  4LR7 A;  3DYC A;  5C66 A;  5L0E A;  3NKR A;  5EGH A;  5KXA A;  4YR1 A;  5LRM A;  3UNY A;  3IGZ B;  4GTX A;  1KH9 A;  5IJS A;  2W5S A;  2ZKT A;  1P49 A;  4QAX A;  1AJA A;  2GLQ A;  2D1G A;  3WAV A;  3UN3 A;  3M7V A;  4CYR A;  3IGY B;  4FDI A;  3M8W A;  1ELY A;  3TX0 A;  1HJK A;  1AJD A;  1KHK A;  2GSU A;  2W5T A;  4UPL A;  1EW8 A;  4CXS A;  2X98 A;  1KH7 A;  3NKO A;  3SZZ A;  4MHX A;  3NKP A;  1KHJ A;  5LQQ A;  3E2D A;  1AJC A;  5LRN A;  5AJ9 A;  3UN2 A;  2GSO A;  2IUC B;  4LRA A;  3BDF A;  3TWZ A;  3UO0 A;  1E1Z P;  1Y6V A;  4KJG A;  4MIV A;  1EJJ A;  4TN0 A;  1ALH A; 
#chains in the Genus database with same CATH homology
 1URA A;  4GTW A;  4KAV A;  4UOP A;  5DLV A;  4FDJ A;  2XR9 A;  1E3C P;  1ANI A;  4LR2 A;  2GA3 A;  1N2L A;  4LRD A;  4NWJ A;  4MY4 A;  5K4P A;  4NWX A;  3MK2 A;  4LQY A;  4B56 A;  1O99 A;  1E33 P;  4LR8 A;  2ANH A;  4KAY A;  3SZY A;  4CXK A;  1ZEF A;  4KJD A;  3ED4 A;  2W5W A;  3WAY A;  3BDG B;  1ELZ A;  1EW2 A;  4LR9 A;  3NKQ A;  1O98 A;  3KD8 A;  1ED9 A;  1FSU A;  4UOR A;  3TG0 A;  3UN5 A;  4ZG7 A;  1HDH A;  2W5V A;  5EGE A;  5GRR A;  5L0K A;  5TJ3 A;  1KH5 A;  1AJB A;  1ZED A;  4ZG9 A;  3WBH A;  1Y7A A;  2G9Y A;  2W5Q A;  5DLW A;  4ZG6 A;  1K7H A;  3BDG A;  1EQJ A;  3WAW A;  4UPH A;  5HRT A;  3T00 A;  4CXU A;  2IUC A;  3OT9 A;  2IFY A;  3DPC A;  1ALJ A;  3IDD A;  3LXQ A;  1KHN A;  4CYS A;  1URB A;  5IJQ A;  2QZU A;  3T02 A;  1ALI A;  2GSN A;  1ELX A;  4LRB A;  5LIA A;  1B8J A;  5L0B A;  1ZEB A;  1AUK A;  3A52 A;  1ALK A;  1ANJ A;  1SHN A;  3NKN A;  2W5X A;  1EI6 A;  1KHL A;  1ED8 A;  4GTZ A;  4LRE A;  4UPI A;  3B5Q A;  4ZGA A;  3T01 A;  3NKM A;  3BDH A;  2XRG A;  3M8Y A;  3MK0 A;  4LRC A;  4LRF A;  5INH A;  1EW9 A;  2W8S A;  3CMR A;  3M8Z A;  5DLT A;  5GOV A;  3NVL A;  1KH4 A;  4KM4 A;  4UPK A;  2RH6 A;  1N2K A;  4GTY A;  4UOO A;  3Q3Q A;  1SHQ A;  2W8D A;  1E2S P;  2W5R A;  3WAX A;  4N7T A;  1HQA A;  3MK1 A;  2VQR A;  4LR7 A;  3DYC A;  5C66 A;  5L0E A;  3NKR A;  5EGH A;  5KXA A;  4YR1 A;  5LRM A;  3UNY A;  3IGZ B;  4GTX A;  1KH9 A;  5IJS A;  2W5S A;  2ZKT A;  1P49 A;  4QAX A;  1AJA A;  2GLQ A;  2D1G A;  3WAV A;  3UN3 A;  3M7V A;  4CYR A;  3IGY B;  4FDI A;  3M8W A;  1ELY A;  3TX0 A;  1HJK A;  1AJD A;  1KHK A;  2GSU A;  2W5T A;  4UPL A;  1EW8 A;  4CXS A;  2X98 A;  1KH7 A;  3NKO A;  3SZZ A;  4MHX A;  3NKP A;  1KHJ A;  5LQQ A;  3E2D A;  1AJC A;  5LRN A;  5AJ9 A;  3UN2 A;  2GSO A;  2IUC B;  4LRA A;  3BDF A;  3TWZ A;  3UO0 A;  1E1Z P;  1Y6V A;  4KJG A;  4MIV A;  1EJJ A;  4TN0 A;  1ALH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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