3BDHA

Crystal structure of zinc-deficient wild-type e. coli alkaline phosphatase
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
Knots found
sequence length
449
structure length
449
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Alkaline phosphatase
publication title The Active-Site Trimetallic Cluster of Alkaline Phosphatase is Lost Upon Isosteric Mutation at the Mg2+-Coordinating Residue Threonine-155
rcsb
source organism Escherichia coli
total genus 154
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2007-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3bdhA00
4LRBA 3SZZA 3IGYB 4KJGA 3T02A 1AJAA 5DLTA 4LR7A 4UOPA 2G9YA 3KD8A 5L0BA 5EGEA 4LRCA 3MK0A 4UPHA 2GSOA 3UN3A 4FDJA 1EW9A 4CYSA 2W5VA 3CMRA 3M8ZA 4MHXA 1ZEFA 2VQRA 4MY4A 1AUKA 4KAYA 3E2DA 1KHJA 5LQQA 4ZG6A 1ALKA 4GTXA 4KAVA 5GRRA 3TWZA 1ALHA 1SHNA 3DYCA 4GTZA 4UORA 3UN2A 4CYRA 3NKOA 4LQYA 3M7VA 4KM4A 1URAA 4KJDA 4ZG9A 5IJSA 2GSNA 3M8WA 3NVLA 5C66A 1ELZA 1AJCA 1EW2A 3WBHA 3DPCA 1Y6VA 3MK1A 3TX0A 5INHA 3T01A 5LIAA 1EW8A 1URBA 5DLWA 4QAXA 1B8JA 2W5QA 4UOOA 1ANIA 2W5XA 3BDGA 2XRGA 2X98A 3A52A 3LXQA 5LRNA 1KHLA 3BDGB 3OT9A 4N7TA 2GA3A 4CXKA 1ALIA 1ELXA 3IGZB 5AJ9A 4NWXA 2GSUA 1ALJA 1K7HA 1KH4A 2GLQA 2W5WA 2IFYA 1FSUA 2ZKTA 1ZEDA 5K4PA 2IUCA 4GTYA 5IJQA 5TJ3A 1P49A 2QZUA 3NKMA 3WAXA 2RH6A 2IUCB 2W5RA 3NKRA 4LR8A 3UO0A 1E2SP 3SZYA 5L0KA 1EI6A 5HRTA 1HJKA 4B56A 1N2KA 4MIVA 2XR9A 1KH9A 4LR9A 4GTWA 4ZG7A 1E33P 3TG0A 3UN5A 3NKPA 5KXAA 2W5SA 1O98A 3WAVA 1HQAA 5L0EA 4LREA 4CXUA 2W8SA 3NKNA 1E1ZP 3M8YA 3T00A 4ZGAA 3BDHA 1Y7AA 4LRDA 1ED8A 1O99A 1ELYA 4UPLA 1ANJA 1EQJA 1HDHA 1KH5A 4TN0A 5EGHA 3Q3QA 3ED4A 3WAWA 1EJJA 3IDDA 4NWJA 3MK2A 4LRFA 4FDIA 1AJDA 2W8DA 1AJBA 5GOVA 1KHNA 2D1GA 4YR1A 3B5QA 4LR2A 4UPIA 1ZEBA 3BDFA 1KHKA 1SHQA 2W5TA 3UNYA 1ED9A 5DLVA 3WAYA 5LRMA 1E3CP 2ANHA 4LRAA 4UPKA 1N2LA 3NKQA 4CXSA 1KH7A
chains in the Genus database with same CATH superfamily
4LRBA 3SZZA 3IGYB 4KJGA 3T02A 1AJAA 5DLTA 4LR7A 4UOPA 2G9YA 3KD8A 5L0BA 5EGEA 4LRCA 3MK0A 4UPHA 2GSOA 3UN3A 4FDJA 1EW9A 4CYSA 2W5VA 3CMRA 3M8ZA 4MHXA 1ZEFA 2VQRA 4MY4A 1AUKA 4KAYA 3E2DA 1KHJA 5LQQA 4ZG6A 1ALKA 4GTXA 4KAVA 5GRRA 3TWZA 1ALHA 1SHNA 3DYCA 4GTZA 4UORA 3UN2A 4CYRA 3NKOA 4LQYA 3M7VA 4KM4A 1URAA 4KJDA 4ZG9A 5IJSA 2GSNA 3M8WA 3NVLA 5C66A 1ELZA 1AJCA 1EW2A 3WBHA 3DPCA 1Y6VA 3MK1A 3TX0A 5INHA 3T01A 5LIAA 1EW8A 1URBA 5DLWA 4QAXA 1B8JA 2W5QA 4UOOA 1ANIA 2W5XA 3BDGA 2XRGA 2X98A 3A52A 3LXQA 5LRNA 1KHLA 3BDGB 3OT9A 4N7TA 2GA3A 4CXKA 1ALIA 1ELXA 3IGZB 5AJ9A 4NWXA 2GSUA 1ALJA 1K7HA 1KH4A 2GLQA 2W5WA 2IFYA 1FSUA 2ZKTA 1ZEDA 5K4PA 2IUCA 4GTYA 5IJQA 5TJ3A 1P49A 2QZUA 3NKMA 3WAXA 2RH6A 2IUCB 2W5RA 3NKRA 4LR8A 3UO0A 1E2SP 3SZYA 5L0KA 1EI6A 5HRTA 1HJKA 4B56A 1N2KA 4MIVA 2XR9A 1KH9A 4LR9A 4GTWA 4ZG7A 1E33P 3TG0A 3UN5A 3NKPA 5KXAA 2W5SA 1O98A 3WAVA 1HQAA 5L0EA 4LREA 4CXUA 2W8SA 3NKNA 1E1ZP 3M8YA 3T00A 4ZGAA 3BDHA 1Y7AA 4LRDA 1ED8A 1O99A 1ELYA 4UPLA 1ANJA 1EQJA 1HDHA 1KH5A 4TN0A 5EGHA 3Q3QA 3ED4A 3WAWA 1EJJA 3IDDA 4NWJA 3MK2A 4LRFA 4FDIA 1AJDA 2W8DA 1AJBA 5GOVA 1KHNA 2D1GA 4YR1A 3B5QA 4LR2A 4UPIA 1ZEBA 3BDFA 1KHKA 1SHQA 2W5TA 3UNYA 1ED9A 5DLVA 3WAYA 5LRMA 1E3CP 2ANHA 4LRAA 4UPKA 1N2LA 3NKQA 4CXSA 1KH7A
chains in the Genus database with same CATH topology
4LRBA 3SZZA 3IGYB 4KJGA 3T02A 1AJAA 5DLTA 4LR7A 4UOPA 2G9YA 3KD8A 5L0BA 5EGEA 4LRCA 3MK0A 4UPHA 2GSOA 3UN3A 4FDJA 1EW9A 4CYSA 2W5VA 3CMRA 3M8ZA 4MHXA 1ZEFA 2VQRA 4MY4A 1AUKA 4KAYA 3E2DA 1KHJA 5LQQA 4ZG6A 1ALKA 4GTXA 4KAVA 5GRRA 3TWZA 1ALHA 1SHNA 3DYCA 4GTZA 4UORA 3UN2A 4CYRA 3NKOA 4LQYA 3M7VA 4KM4A 1URAA 4KJDA 4ZG9A 5IJSA 2GSNA 3M8WA 3NVLA 5C66A 1ELZA 1AJCA 1EW2A 3WBHA 3DPCA 1Y6VA 3MK1A 3TX0A 5INHA 3T01A 5LIAA 1EW8A 1URBA 5DLWA 4QAXA 1B8JA 2W5QA 4UOOA 1ANIA 2W5XA 3BDGA 2XRGA 2X98A 3A52A 3LXQA 5LRNA 1KHLA 3BDGB 3OT9A 4N7TA 2GA3A 4CXKA 1ALIA 1ELXA 3IGZB 5AJ9A 4NWXA 2GSUA 1ALJA 1K7HA 1KH4A 2GLQA 2W5WA 2IFYA 1FSUA 2ZKTA 1ZEDA 5K4PA 2IUCA 4GTYA 5IJQA 5TJ3A 1P49A 2QZUA 3NKMA 3WAXA 2RH6A 2IUCB 2W5RA 3NKRA 4LR8A 3UO0A 1E2SP 3SZYA 5L0KA 1EI6A 5HRTA 1HJKA 4B56A 1N2KA 4MIVA 2XR9A 1KH9A 4LR9A 4GTWA 4ZG7A 1E33P 3TG0A 3UN5A 3NKPA 5KXAA 2W5SA 1O98A 3WAVA 1HQAA 5L0EA 4LREA 4CXUA 2W8SA 3NKNA 1E1ZP 3M8YA 3T00A 4ZGAA 3BDHA 1Y7AA 4LRDA 1ED8A 1O99A 1ELYA 4UPLA 1ANJA 1EQJA 1HDHA 1KH5A 4TN0A 5EGHA 3Q3QA 3ED4A 3WAWA 1EJJA 3IDDA 4NWJA 3MK2A 4LRFA 4FDIA 1AJDA 2W8DA 1AJBA 5GOVA 1KHNA 2D1GA 4YR1A 3B5QA 4LR2A 4UPIA 1ZEBA 3BDFA 1KHKA 1SHQA 2W5TA 3UNYA 1ED9A 5DLVA 3WAYA 5LRMA 1E3CP 2ANHA 4LRAA 4UPKA 1N2LA 3NKQA 4CXSA 1KH7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LRB A;  3SZZ A;  3IGY B;  4KJG A;  3T02 A;  1AJA A;  5DLT A;  4LR7 A;  4UOP A;  2G9Y A;  3KD8 A;  5L0B A;  5EGE A;  4LRC A;  3MK0 A;  4UPH A;  2GSO A;  3UN3 A;  4FDJ A;  1EW9 A;  4CYS A;  2W5V A;  3CMR A;  3M8Z A;  4MHX A;  1ZEF A;  2VQR A;  4MY4 A;  1AUK A;  4KAY A;  3E2D A;  1KHJ A;  5LQQ A;  4ZG6 A;  1ALK A;  4GTX A;  4KAV A;  5GRR A;  3TWZ A;  1ALH A;  1SHN A;  3DYC A;  4GTZ A;  4UOR A;  3UN2 A;  4CYR A;  3NKO A;  4LQY A;  3M7V A;  4KM4 A;  1URA A;  4KJD A;  4ZG9 A;  5IJS A;  2GSN A;  3M8W A;  3NVL A;  5C66 A;  1ELZ A;  1AJC A;  1EW2 A;  3WBH A;  3DPC A;  1Y6V A;  3MK1 A;  3TX0 A;  5INH A;  3T01 A;  5LIA A;  1EW8 A;  1URB A;  5DLW A;  4QAX A;  1B8J A;  2W5Q A;  4UOO A;  1ANI A;  2W5X A;  3BDG A;  2XRG A;  2X98 A;  3A52 A;  3LXQ A;  5LRN A;  1KHL A;  3BDG B;  3OT9 A;  4N7T A;  2GA3 A;  4CXK A;  1ALI A;  1ELX A;  3IGZ B;  5AJ9 A;  4NWX A;  2GSU A;  1ALJ A;  1K7H A;  1KH4 A;  2GLQ A;  2W5W A;  2IFY A;  1FSU A;  2ZKT A;  1ZED A;  5K4P A;  2IUC A;  4GTY A;  5IJQ A;  5TJ3 A;  1P49 A;  2QZU A;  3NKM A;  3WAX A;  2RH6 A;  2IUC B;  2W5R A;  3NKR A;  4LR8 A;  3UO0 A;  1E2S P;  3SZY A;  5L0K A;  1EI6 A;  5HRT A;  1HJK A;  4B56 A;  1N2K A;  4MIV A;  2XR9 A;  1KH9 A;  4LR9 A;  4GTW A;  4ZG7 A;  1E33 P;  3TG0 A;  3UN5 A;  3NKP A;  5KXA A;  2W5S A;  1O98 A;  3WAV A;  1HQA A;  5L0E A;  4LRE A;  4CXU A;  2W8S A;  3NKN A;  1E1Z P;  3M8Y A;  3T00 A;  4ZGA A;  3BDH A;  1Y7A A;  4LRD A;  1ED8 A;  1O99 A;  1ELY A;  4UPL A;  1ANJ A;  1EQJ A;  1HDH A;  1KH5 A;  4TN0 A;  5EGH A;  3Q3Q A;  3ED4 A;  3WAW A;  1EJJ A;  3IDD A;  4NWJ A;  3MK2 A;  4LRF A;  4FDI A;  1AJD A;  2W8D A;  1AJB A;  5GOV A;  1KHN A;  2D1G A;  4YR1 A;  3B5Q A;  4LR2 A;  4UPI A;  1ZEB A;  3BDF A;  1KHK A;  1SHQ A;  2W5T A;  3UNY A;  1ED9 A;  5DLV A;  3WAY A;  5LRM A;  1E3C P;  2ANH A;  4LRA A;  4UPK A;  1N2L A;  3NKQ A;  4CXS A;  1KH7 A; 
#chains in the Genus database with same CATH topology
 4LRB A;  3SZZ A;  3IGY B;  4KJG A;  3T02 A;  1AJA A;  5DLT A;  4LR7 A;  4UOP A;  2G9Y A;  3KD8 A;  5L0B A;  5EGE A;  4LRC A;  3MK0 A;  4UPH A;  2GSO A;  3UN3 A;  4FDJ A;  1EW9 A;  4CYS A;  2W5V A;  3CMR A;  3M8Z A;  4MHX A;  1ZEF A;  2VQR A;  4MY4 A;  1AUK A;  4KAY A;  3E2D A;  1KHJ A;  5LQQ A;  4ZG6 A;  1ALK A;  4GTX A;  4KAV A;  5GRR A;  3TWZ A;  1ALH A;  1SHN A;  3DYC A;  4GTZ A;  4UOR A;  3UN2 A;  4CYR A;  3NKO A;  4LQY A;  3M7V A;  4KM4 A;  1URA A;  4KJD A;  4ZG9 A;  5IJS A;  2GSN A;  3M8W A;  3NVL A;  5C66 A;  1ELZ A;  1AJC A;  1EW2 A;  3WBH A;  3DPC A;  1Y6V A;  3MK1 A;  3TX0 A;  5INH A;  3T01 A;  5LIA A;  1EW8 A;  1URB A;  5DLW A;  4QAX A;  1B8J A;  2W5Q A;  4UOO A;  1ANI A;  2W5X A;  3BDG A;  2XRG A;  2X98 A;  3A52 A;  3LXQ A;  5LRN A;  1KHL A;  3BDG B;  3OT9 A;  4N7T A;  2GA3 A;  4CXK A;  1ALI A;  1ELX A;  3IGZ B;  5AJ9 A;  4NWX A;  2GSU A;  1ALJ A;  1K7H A;  1KH4 A;  2GLQ A;  2W5W A;  2IFY A;  1FSU A;  2ZKT A;  1ZED A;  5K4P A;  2IUC A;  4GTY A;  5IJQ A;  5TJ3 A;  1P49 A;  2QZU A;  3NKM A;  3WAX A;  2RH6 A;  2IUC B;  2W5R A;  3NKR A;  4LR8 A;  3UO0 A;  1E2S P;  3SZY A;  5L0K A;  1EI6 A;  5HRT A;  1HJK A;  4B56 A;  1N2K A;  4MIV A;  2XR9 A;  1KH9 A;  4LR9 A;  4GTW A;  4ZG7 A;  1E33 P;  3TG0 A;  3UN5 A;  3NKP A;  5KXA A;  2W5S A;  1O98 A;  3WAV A;  1HQA A;  5L0E A;  4LRE A;  4CXU A;  2W8S A;  3NKN A;  1E1Z P;  3M8Y A;  3T00 A;  4ZGA A;  3BDH A;  1Y7A A;  4LRD A;  1ED8 A;  1O99 A;  1ELY A;  4UPL A;  1ANJ A;  1EQJ A;  1HDH A;  1KH5 A;  4TN0 A;  5EGH A;  3Q3Q A;  3ED4 A;  3WAW A;  1EJJ A;  3IDD A;  4NWJ A;  3MK2 A;  4LRF A;  4FDI A;  1AJD A;  2W8D A;  1AJB A;  5GOV A;  1KHN A;  2D1G A;  4YR1 A;  3B5Q A;  4LR2 A;  4UPI A;  1ZEB A;  3BDF A;  1KHK A;  1SHQ A;  2W5T A;  3UNY A;  1ED9 A;  5DLV A;  3WAY A;  5LRM A;  1E3C P;  2ANH A;  4LRA A;  4UPK A;  1N2L A;  3NKQ A;  4CXS A;  1KH7 A; 
#chains in the Genus database with same CATH homology
 4LRB A;  3SZZ A;  3IGY B;  4KJG A;  3T02 A;  1AJA A;  5DLT A;  4LR7 A;  4UOP A;  2G9Y A;  3KD8 A;  5L0B A;  5EGE A;  4LRC A;  3MK0 A;  4UPH A;  2GSO A;  3UN3 A;  4FDJ A;  1EW9 A;  4CYS A;  2W5V A;  3CMR A;  3M8Z A;  4MHX A;  1ZEF A;  2VQR A;  4MY4 A;  1AUK A;  4KAY A;  3E2D A;  1KHJ A;  5LQQ A;  4ZG6 A;  1ALK A;  4GTX A;  4KAV A;  5GRR A;  3TWZ A;  1ALH A;  1SHN A;  3DYC A;  4GTZ A;  4UOR A;  3UN2 A;  4CYR A;  3NKO A;  4LQY A;  3M7V A;  4KM4 A;  1URA A;  4KJD A;  4ZG9 A;  5IJS A;  2GSN A;  3M8W A;  3NVL A;  5C66 A;  1ELZ A;  1AJC A;  1EW2 A;  3WBH A;  3DPC A;  1Y6V A;  3MK1 A;  3TX0 A;  5INH A;  3T01 A;  5LIA A;  1EW8 A;  1URB A;  5DLW A;  4QAX A;  1B8J A;  2W5Q A;  4UOO A;  1ANI A;  2W5X A;  3BDG A;  2XRG A;  2X98 A;  3A52 A;  3LXQ A;  5LRN A;  1KHL A;  3BDG B;  3OT9 A;  4N7T A;  2GA3 A;  4CXK A;  1ALI A;  1ELX A;  3IGZ B;  5AJ9 A;  4NWX A;  2GSU A;  1ALJ A;  1K7H A;  1KH4 A;  2GLQ A;  2W5W A;  2IFY A;  1FSU A;  2ZKT A;  1ZED A;  5K4P A;  2IUC A;  4GTY A;  5IJQ A;  5TJ3 A;  1P49 A;  2QZU A;  3NKM A;  3WAX A;  2RH6 A;  2IUC B;  2W5R A;  3NKR A;  4LR8 A;  3UO0 A;  1E2S P;  3SZY A;  5L0K A;  1EI6 A;  5HRT A;  1HJK A;  4B56 A;  1N2K A;  4MIV A;  2XR9 A;  1KH9 A;  4LR9 A;  4GTW A;  4ZG7 A;  1E33 P;  3TG0 A;  3UN5 A;  3NKP A;  5KXA A;  2W5S A;  1O98 A;  3WAV A;  1HQA A;  5L0E A;  4LRE A;  4CXU A;  2W8S A;  3NKN A;  1E1Z P;  3M8Y A;  3T00 A;  4ZGA A;  3BDH A;  1Y7A A;  4LRD A;  1ED8 A;  1O99 A;  1ELY A;  4UPL A;  1ANJ A;  1EQJ A;  1HDH A;  1KH5 A;  4TN0 A;  5EGH A;  3Q3Q A;  3ED4 A;  3WAW A;  1EJJ A;  3IDD A;  4NWJ A;  3MK2 A;  4LRF A;  4FDI A;  1AJD A;  2W8D A;  1AJB A;  5GOV A;  1KHN A;  2D1G A;  4YR1 A;  3B5Q A;  4LR2 A;  4UPI A;  1ZEB A;  3BDF A;  1KHK A;  1SHQ A;  2W5T A;  3UNY A;  1ED9 A;  5DLV A;  3WAY A;  5LRM A;  1E3C P;  2ANH A;  4LRA A;  4UPK A;  1N2L A;  3NKQ A;  4CXS A;  1KH7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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