3TG0A

E. coli alkaline phosphatase with bound inorganic phosphate
Total Genus 164
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
164
Knots found
sequence length
440
structure length
440
Chain Sequence
NRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Alkaline phosphatase
publication title High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography.
pubmed doi rcsb
source organism Escherichia coli
total genus 164
structure length 440
sequence length 440
chains with identical sequence B, C, D
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 3tg0A00
1ELXA 3T01A 5GRRA 1SHNA 1ZEFA 2ZKTA 3TX0A 5IJSA 4LQYA 3UN2A 3LXQA 4TN0A 1AUKA 1E3CP 2ANHA 1KHNA 3TG0A 2GSUA 3M7VA 4LRBA 4CXSA 5LRNA 4CXUA 4NWJA 5IJQA 3IGZB 5DLTA 4LRDA 1ED9A 5LIAA 1ALKA 1ANJA 3WAYA 3A52A 3IDDA 5HRTA 1ED8A 3NVLA 2XRGA 4KAVA 2W5XA 2W5QA 1KHKA 3M8WA 2VQRA 1EJJA 1KH9A 4LRFA 4UOOA 1URAA 1ZEDA 2W5TA 5TJ3A 1K7HA 3SZZA 1EW2A 3UO0A 1N2KA 2QZUA 2W5SA 4GTYA 1HJKA 3NKQA 3T02A 2IUCA 4ZG6A 5LQQA 2W5RA 5INHA 4CYRA 4ZGAA 5L0BA 1ANIA 1B8JA 2IUCB 5KXAA 4KJGA 4CXKA 2GSNA 2GA3A 5DLVA 3ED4A 5AJ9A 1Y6VA 3WAXA 4LRAA 1EQJA 3B5QA 3WAVA 4GTWA 4KAYA 4MHXA 2W8SA 3E2DA 2GSOA 5EGEA 1AJAA 1ALHA 1ZEBA 1KHJA 1E1ZP 4LRCA 4ZG7A 4LR7A 4GTXA 5K4PA 4UPLA 2G9YA 3NKPA 1ELZA 3NKMA 4UPHA 1E2SP 4FDIA 1Y7AA 3BDGB 4UPKA 4ZG9A 4B56A 1AJBA 3UN3A 1P49A 4LR2A 3KD8A 3UN5A 3CMRA 4LR9A 5EGHA 3IGYB 3DYCA 4GTZA 4UOPA 3BDHA 1URBA 3NKNA 1AJCA 3M8YA 2W5VA 4LREA 3OT9A 3WAWA 2RH6A 5LRMA 4YR1A 4UPIA 1SHQA 1N2LA 1FSUA 4MIVA 1E33P 3MK1A 2XR9A 4CYSA 1KHLA 1O99A 3BDFA 1EI6A 4UORA 1ALIA 3NKOA 4QAXA 1EW8A 4MY4A 3SZYA 1O98A 3M8ZA 2GLQA 5C66A 4FDJA 1ALJA 4NWXA 3UNYA 3WBHA 1KH5A 2W8DA 3TWZA 4N7TA 2D1GA 2W5WA 3MK2A 2IFYA 5L0KA 5L0EA 4LR8A 1HQAA 1ELYA 1KH4A 1EW9A 3BDGA 3DPCA 4KM4A 3Q3QA 2X98A 3NKRA 3MK0A 1AJDA 5GOVA 1KH7A 3T00A 4KJDA 1HDHA 5DLWA
chains in the Genus database with same CATH superfamily
1ELXA 3T01A 5GRRA 1SHNA 1ZEFA 2ZKTA 3TX0A 5IJSA 4LQYA 3UN2A 3LXQA 4TN0A 1AUKA 1E3CP 2ANHA 1KHNA 3TG0A 2GSUA 3M7VA 4LRBA 4CXSA 5LRNA 4CXUA 4NWJA 5IJQA 3IGZB 5DLTA 4LRDA 1ED9A 5LIAA 1ALKA 1ANJA 3WAYA 3A52A 3IDDA 5HRTA 1ED8A 3NVLA 2XRGA 4KAVA 2W5XA 2W5QA 1KHKA 3M8WA 2VQRA 1EJJA 1KH9A 4LRFA 4UOOA 1URAA 1ZEDA 2W5TA 5TJ3A 1K7HA 3SZZA 1EW2A 3UO0A 1N2KA 2QZUA 2W5SA 4GTYA 1HJKA 3NKQA 3T02A 2IUCA 4ZG6A 5LQQA 2W5RA 5INHA 4CYRA 4ZGAA 5L0BA 1ANIA 1B8JA 2IUCB 5KXAA 4KJGA 4CXKA 2GSNA 2GA3A 5DLVA 3ED4A 5AJ9A 1Y6VA 3WAXA 4LRAA 1EQJA 3B5QA 3WAVA 4GTWA 4KAYA 4MHXA 2W8SA 3E2DA 2GSOA 5EGEA 1AJAA 1ALHA 1ZEBA 1KHJA 1E1ZP 4LRCA 4ZG7A 4LR7A 4GTXA 5K4PA 4UPLA 2G9YA 3NKPA 1ELZA 3NKMA 4UPHA 1E2SP 4FDIA 1Y7AA 3BDGB 4UPKA 4ZG9A 4B56A 1AJBA 3UN3A 1P49A 4LR2A 3KD8A 3UN5A 3CMRA 4LR9A 5EGHA 3IGYB 3DYCA 4GTZA 4UOPA 3BDHA 1URBA 3NKNA 1AJCA 3M8YA 2W5VA 4LREA 3OT9A 3WAWA 2RH6A 5LRMA 4YR1A 4UPIA 1SHQA 1N2LA 1FSUA 4MIVA 1E33P 3MK1A 2XR9A 4CYSA 1KHLA 1O99A 3BDFA 1EI6A 4UORA 1ALIA 3NKOA 4QAXA 1EW8A 4MY4A 3SZYA 1O98A 3M8ZA 2GLQA 5C66A 4FDJA 1ALJA 4NWXA 3UNYA 3WBHA 1KH5A 2W8DA 3TWZA 4N7TA 2D1GA 2W5WA 3MK2A 2IFYA 5L0KA 5L0EA 4LR8A 1HQAA 1ELYA 1KH4A 1EW9A 3BDGA 3DPCA 4KM4A 3Q3QA 2X98A 3NKRA 3MK0A 1AJDA 5GOVA 1KH7A 3T00A 4KJDA 1HDHA 5DLWA
chains in the Genus database with same CATH topology
1ELXA 3T01A 5GRRA 1SHNA 1ZEFA 2ZKTA 3TX0A 5IJSA 4LQYA 3UN2A 3LXQA 4TN0A 1AUKA 1E3CP 2ANHA 1KHNA 3TG0A 2GSUA 3M7VA 4LRBA 4CXSA 5LRNA 4CXUA 4NWJA 5IJQA 3IGZB 5DLTA 4LRDA 1ED9A 5LIAA 1ALKA 1ANJA 3WAYA 3A52A 3IDDA 5HRTA 1ED8A 3NVLA 2XRGA 4KAVA 2W5XA 2W5QA 1KHKA 3M8WA 2VQRA 1EJJA 1KH9A 4LRFA 4UOOA 1URAA 1ZEDA 2W5TA 5TJ3A 1K7HA 3SZZA 1EW2A 3UO0A 1N2KA 2QZUA 2W5SA 4GTYA 1HJKA 3NKQA 3T02A 2IUCA 4ZG6A 5LQQA 2W5RA 5INHA 4CYRA 4ZGAA 5L0BA 1ANIA 1B8JA 2IUCB 5KXAA 4KJGA 4CXKA 2GSNA 2GA3A 5DLVA 3ED4A 5AJ9A 1Y6VA 3WAXA 4LRAA 1EQJA 3B5QA 3WAVA 4GTWA 4KAYA 4MHXA 2W8SA 3E2DA 2GSOA 5EGEA 1AJAA 1ALHA 1ZEBA 1KHJA 1E1ZP 4LRCA 4ZG7A 4LR7A 4GTXA 5K4PA 4UPLA 2G9YA 3NKPA 1ELZA 3NKMA 4UPHA 1E2SP 4FDIA 1Y7AA 3BDGB 4UPKA 4ZG9A 4B56A 1AJBA 3UN3A 1P49A 4LR2A 3KD8A 3UN5A 3CMRA 4LR9A 5EGHA 3IGYB 3DYCA 4GTZA 4UOPA 3BDHA 1URBA 3NKNA 1AJCA 3M8YA 2W5VA 4LREA 3OT9A 3WAWA 2RH6A 5LRMA 4YR1A 4UPIA 1SHQA 1N2LA 1FSUA 4MIVA 1E33P 3MK1A 2XR9A 4CYSA 1KHLA 1O99A 3BDFA 1EI6A 4UORA 1ALIA 3NKOA 4QAXA 1EW8A 4MY4A 3SZYA 1O98A 3M8ZA 2GLQA 5C66A 4FDJA 1ALJA 4NWXA 3UNYA 3WBHA 1KH5A 2W8DA 3TWZA 4N7TA 2D1GA 2W5WA 3MK2A 2IFYA 5L0KA 5L0EA 4LR8A 1HQAA 1ELYA 1KH4A 1EW9A 3BDGA 3DPCA 4KM4A 3Q3QA 2X98A 3NKRA 3MK0A 1AJDA 5GOVA 1KH7A 3T00A 4KJDA 1HDHA 5DLWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ELX A;  3T01 A;  5GRR A;  1SHN A;  1ZEF A;  2ZKT A;  3TX0 A;  5IJS A;  4LQY A;  3UN2 A;  3LXQ A;  4TN0 A;  1AUK A;  1E3C P;  2ANH A;  1KHN A;  3TG0 A;  2GSU A;  3M7V A;  4LRB A;  4CXS A;  5LRN A;  4CXU A;  4NWJ A;  5IJQ A;  3IGZ B;  5DLT A;  4LRD A;  1ED9 A;  5LIA A;  1ALK A;  1ANJ A;  3WAY A;  3A52 A;  3IDD A;  5HRT A;  1ED8 A;  3NVL A;  2XRG A;  4KAV A;  2W5X A;  2W5Q A;  1KHK A;  3M8W A;  2VQR A;  1EJJ A;  1KH9 A;  4LRF A;  4UOO A;  1URA A;  1ZED A;  2W5T A;  5TJ3 A;  1K7H A;  3SZZ A;  1EW2 A;  3UO0 A;  1N2K A;  2QZU A;  2W5S A;  4GTY A;  1HJK A;  3NKQ A;  3T02 A;  2IUC A;  4ZG6 A;  5LQQ A;  2W5R A;  5INH A;  4CYR A;  4ZGA A;  5L0B A;  1ANI A;  1B8J A;  2IUC B;  5KXA A;  4KJG A;  4CXK A;  2GSN A;  2GA3 A;  5DLV A;  3ED4 A;  5AJ9 A;  1Y6V A;  3WAX A;  4LRA A;  1EQJ A;  3B5Q A;  3WAV A;  4GTW A;  4KAY A;  4MHX A;  2W8S A;  3E2D A;  2GSO A;  5EGE A;  1AJA A;  1ALH A;  1ZEB A;  1KHJ A;  1E1Z P;  4LRC A;  4ZG7 A;  4LR7 A;  4GTX A;  5K4P A;  4UPL A;  2G9Y A;  3NKP A;  1ELZ A;  3NKM A;  4UPH A;  1E2S P;  4FDI A;  1Y7A A;  3BDG B;  4UPK A;  4ZG9 A;  4B56 A;  1AJB A;  3UN3 A;  1P49 A;  4LR2 A;  3KD8 A;  3UN5 A;  3CMR A;  4LR9 A;  5EGH A;  3IGY B;  3DYC A;  4GTZ A;  4UOP A;  3BDH A;  1URB A;  3NKN A;  1AJC A;  3M8Y A;  2W5V A;  4LRE A;  3OT9 A;  3WAW A;  2RH6 A;  5LRM A;  4YR1 A;  4UPI A;  1SHQ A;  1N2L A;  1FSU A;  4MIV A;  1E33 P;  3MK1 A;  2XR9 A;  4CYS A;  1KHL A;  1O99 A;  3BDF A;  1EI6 A;  4UOR A;  1ALI A;  3NKO A;  4QAX A;  1EW8 A;  4MY4 A;  3SZY A;  1O98 A;  3M8Z A;  2GLQ A;  5C66 A;  4FDJ A;  1ALJ A;  4NWX A;  3UNY A;  3WBH A;  1KH5 A;  2W8D A;  3TWZ A;  4N7T A;  2D1G A;  2W5W A;  3MK2 A;  2IFY A;  5L0K A;  5L0E A;  4LR8 A;  1HQA A;  1ELY A;  1KH4 A;  1EW9 A;  3BDG A;  3DPC A;  4KM4 A;  3Q3Q A;  2X98 A;  3NKR A;  3MK0 A;  1AJD A;  5GOV A;  1KH7 A;  3T00 A;  4KJD A;  1HDH A;  5DLW A; 
#chains in the Genus database with same CATH topology
 1ELX A;  3T01 A;  5GRR A;  1SHN A;  1ZEF A;  2ZKT A;  3TX0 A;  5IJS A;  4LQY A;  3UN2 A;  3LXQ A;  4TN0 A;  1AUK A;  1E3C P;  2ANH A;  1KHN A;  3TG0 A;  2GSU A;  3M7V A;  4LRB A;  4CXS A;  5LRN A;  4CXU A;  4NWJ A;  5IJQ A;  3IGZ B;  5DLT A;  4LRD A;  1ED9 A;  5LIA A;  1ALK A;  1ANJ A;  3WAY A;  3A52 A;  3IDD A;  5HRT A;  1ED8 A;  3NVL A;  2XRG A;  4KAV A;  2W5X A;  2W5Q A;  1KHK A;  3M8W A;  2VQR A;  1EJJ A;  1KH9 A;  4LRF A;  4UOO A;  1URA A;  1ZED A;  2W5T A;  5TJ3 A;  1K7H A;  3SZZ A;  1EW2 A;  3UO0 A;  1N2K A;  2QZU A;  2W5S A;  4GTY A;  1HJK A;  3NKQ A;  3T02 A;  2IUC A;  4ZG6 A;  5LQQ A;  2W5R A;  5INH A;  4CYR A;  4ZGA A;  5L0B A;  1ANI A;  1B8J A;  2IUC B;  5KXA A;  4KJG A;  4CXK A;  2GSN A;  2GA3 A;  5DLV A;  3ED4 A;  5AJ9 A;  1Y6V A;  3WAX A;  4LRA A;  1EQJ A;  3B5Q A;  3WAV A;  4GTW A;  4KAY A;  4MHX A;  2W8S A;  3E2D A;  2GSO A;  5EGE A;  1AJA A;  1ALH A;  1ZEB A;  1KHJ A;  1E1Z P;  4LRC A;  4ZG7 A;  4LR7 A;  4GTX A;  5K4P A;  4UPL A;  2G9Y A;  3NKP A;  1ELZ A;  3NKM A;  4UPH A;  1E2S P;  4FDI A;  1Y7A A;  3BDG B;  4UPK A;  4ZG9 A;  4B56 A;  1AJB A;  3UN3 A;  1P49 A;  4LR2 A;  3KD8 A;  3UN5 A;  3CMR A;  4LR9 A;  5EGH A;  3IGY B;  3DYC A;  4GTZ A;  4UOP A;  3BDH A;  1URB A;  3NKN A;  1AJC A;  3M8Y A;  2W5V A;  4LRE A;  3OT9 A;  3WAW A;  2RH6 A;  5LRM A;  4YR1 A;  4UPI A;  1SHQ A;  1N2L A;  1FSU A;  4MIV A;  1E33 P;  3MK1 A;  2XR9 A;  4CYS A;  1KHL A;  1O99 A;  3BDF A;  1EI6 A;  4UOR A;  1ALI A;  3NKO A;  4QAX A;  1EW8 A;  4MY4 A;  3SZY A;  1O98 A;  3M8Z A;  2GLQ A;  5C66 A;  4FDJ A;  1ALJ A;  4NWX A;  3UNY A;  3WBH A;  1KH5 A;  2W8D A;  3TWZ A;  4N7T A;  2D1G A;  2W5W A;  3MK2 A;  2IFY A;  5L0K A;  5L0E A;  4LR8 A;  1HQA A;  1ELY A;  1KH4 A;  1EW9 A;  3BDG A;  3DPC A;  4KM4 A;  3Q3Q A;  2X98 A;  3NKR A;  3MK0 A;  1AJD A;  5GOV A;  1KH7 A;  3T00 A;  4KJD A;  1HDH A;  5DLW A; 
#chains in the Genus database with same CATH homology
 1ELX A;  3T01 A;  5GRR A;  1SHN A;  1ZEF A;  2ZKT A;  3TX0 A;  5IJS A;  4LQY A;  3UN2 A;  3LXQ A;  4TN0 A;  1AUK A;  1E3C P;  2ANH A;  1KHN A;  3TG0 A;  2GSU A;  3M7V A;  4LRB A;  4CXS A;  5LRN A;  4CXU A;  4NWJ A;  5IJQ A;  3IGZ B;  5DLT A;  4LRD A;  1ED9 A;  5LIA A;  1ALK A;  1ANJ A;  3WAY A;  3A52 A;  3IDD A;  5HRT A;  1ED8 A;  3NVL A;  2XRG A;  4KAV A;  2W5X A;  2W5Q A;  1KHK A;  3M8W A;  2VQR A;  1EJJ A;  1KH9 A;  4LRF A;  4UOO A;  1URA A;  1ZED A;  2W5T A;  5TJ3 A;  1K7H A;  3SZZ A;  1EW2 A;  3UO0 A;  1N2K A;  2QZU A;  2W5S A;  4GTY A;  1HJK A;  3NKQ A;  3T02 A;  2IUC A;  4ZG6 A;  5LQQ A;  2W5R A;  5INH A;  4CYR A;  4ZGA A;  5L0B A;  1ANI A;  1B8J A;  2IUC B;  5KXA A;  4KJG A;  4CXK A;  2GSN A;  2GA3 A;  5DLV A;  3ED4 A;  5AJ9 A;  1Y6V A;  3WAX A;  4LRA A;  1EQJ A;  3B5Q A;  3WAV A;  4GTW A;  4KAY A;  4MHX A;  2W8S A;  3E2D A;  2GSO A;  5EGE A;  1AJA A;  1ALH A;  1ZEB A;  1KHJ A;  1E1Z P;  4LRC A;  4ZG7 A;  4LR7 A;  4GTX A;  5K4P A;  4UPL A;  2G9Y A;  3NKP A;  1ELZ A;  3NKM A;  4UPH A;  1E2S P;  4FDI A;  1Y7A A;  3BDG B;  4UPK A;  4ZG9 A;  4B56 A;  1AJB A;  3UN3 A;  1P49 A;  4LR2 A;  3KD8 A;  3UN5 A;  3CMR A;  4LR9 A;  5EGH A;  3IGY B;  3DYC A;  4GTZ A;  4UOP A;  3BDH A;  1URB A;  3NKN A;  1AJC A;  3M8Y A;  2W5V A;  4LRE A;  3OT9 A;  3WAW A;  2RH6 A;  5LRM A;  4YR1 A;  4UPI A;  1SHQ A;  1N2L A;  1FSU A;  4MIV A;  1E33 P;  3MK1 A;  2XR9 A;  4CYS A;  1KHL A;  1O99 A;  3BDF A;  1EI6 A;  4UOR A;  1ALI A;  3NKO A;  4QAX A;  1EW8 A;  4MY4 A;  3SZY A;  1O98 A;  3M8Z A;  2GLQ A;  5C66 A;  4FDJ A;  1ALJ A;  4NWX A;  3UNY A;  3WBH A;  1KH5 A;  2W8D A;  3TWZ A;  4N7T A;  2D1G A;  2W5W A;  3MK2 A;  2IFY A;  5L0K A;  5L0E A;  4LR8 A;  1HQA A;  1ELY A;  1KH4 A;  1EW9 A;  3BDG A;  3DPC A;  4KM4 A;  3Q3Q A;  2X98 A;  3NKR A;  3MK0 A;  1AJD A;  5GOV A;  1KH7 A;  3T00 A;  4KJD A;  1HDH A;  5DLW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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