4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
2QWVA 5CO4A 1J85A 4YPYA 2EGWA 4MCDA 1MXIA 3OIIA 2O3AA 1V2XA 2QMMA 4YQKA 1GZ0A 1K3RA 4YQSA 1Z85A 4YQBA 4YVKA 1VH0A 4CNEA 5GMBA 3AI9X 3KW2A 3DCMX 2HA8A 4JALA 1O6DA 4YQ1A 4IG6A 2YY8A 3E5YA 4YQ3A 1V6ZA 4YQNA 4YVIA 4L69A 2V3JA 1VHYA 1P9PA 4YQ7A 4YQOA 4JAKA 4XBOA 2EGVA 4YQCA 3QUVA 4YQ8A 4RG1A 4YQQA 2CX8A 1TO0A 4YPXA 2Z0YA 4YQTA 1OY5A 4YQ2A 3NK6A 2I6DA 2NWAA 4YVJA 1IPAA 3AIAA 1X7PA 4YQGA 4YQDA 4YPWA 4J3CA 3O7BA 4CNDA 4YQLA 3AXZA 3BBDA 4KDZA 1ZJRA 1UAJA 3KY7A 3OINA 4E8BA 3ONPA 4X3MA 4YQ5A 3IEFA 4KGNA 1UALA 1UAMA 1NXZA 4YQ4A 4YQ0A 3ILKA 4YVHA 4YQ6A 1VHKA 5GMCA 4YQIA 4CNGA 4PZKA 4YVGA 5D9FA 4YPZA 4FAKA 4X3LA 3L8UA 4H3YA 4YQRA 2V3KA 3BBHA 1UAKA 4YQJA 3GYQA 3NK7A 3IC6A 4MCCA 3BBEA 3N4KA 3KTYA 3OIJA 4MCBA 4YQAA 5FAIA 4YQPA 4CNFA 3N4JA 5GM8A 1X7OA 3KNUA 4YQ9A 4H3ZA 1NS5A
chains in the Genus database with same CATH superfamily
2QWVA 5CO4A 1J85A 4YPYA 2EGWA 4MCDA 1MXIA 5GADW 5GAGW 3OIIA 3CZBA 2O3AA 1V2XA 2G6GA 4JXZA 2QMMA 4WCES 4YQKA 1GZ0A 1K3RA 2HZ7A 4YQSA 1Z85A 1QRUA 4YQBA 4YQ9A 4YVKA 1VH0A 1DFUP 1QTQA 1FEUA 2ZJQS 4CNEA 5GMBA 4WFAS 2GAEA 3AI9X 3KW2A 3DCMX 2HA8A 4JALA 1O6DA 4YQ1A 4U67S 4IG6A 1QRTA 2YY8A 3E5YA 4JWFA 5GAHW 4YQ3A 5DM7S 1V6ZA 2PNWA 4JXXA 4YQNA 2AE0X 4YVIA 4L69A 2PI8A 5IZNA 1VHYA 3X1LB 1P9PA 2V3JA 4YQ7A 4YQOA 4JAKA 2ZJPS 4XBOA 2EGVA 2PJJA 4YQCA 4WFBS 3QUVA 4YQ8A 4RG1A 4YQQA 2CX8A 1TO0A 4JWJA 4YPXA 2Z0YA 4YQTA 1OY5A 4YQ2A 3NK6A 2RD2A 2I6DA 2NWAA 4YVJA 3J7ZV 4IOCS 1IPAA 3AIAA 1X7PA 4FMWA 4YQGA 4YQDA 4JWGA 4YPWA 4J3CA 3CF5S 3O7BA 4H3SA 1O0CA 2ZJRS 4YQLA 4CNDA 1NYLA 3AXZA 3BBDA 4KDZA 1ZJRA 1UAJA 3KY7A 5BNZA 1GTRA 1D6KA 3OINA 4E8BA 3ONPA 3W2WB 4X3MA 4YQ5A 2G5DA 3IEFA 4KGNA 1UALA 4IOAS 1UAMA 1NXZA 4YQ4A 4YQ0A 3ILKA 4YVHA 4H4KA 4YQ6A 1VHKA 5GMCA 1GTSA 4YQIA 4CNGA 4WF9S 1EXDA 4PZKA 4YVGA 5D9FA 5DM6S 4YPZA 5GAEW 4FAKA 4V194 3DLLS 2RE8A 5HL7S 4X3LA 1EUQA 3L8UA 4H3YA 1O0BA 3PIOS 4YQRA 2V3KA 3BBHA 3PIPS 1B75A 4JWHA 5JVGS 4IO9S 1QRSA 1UAKA 4YQJA 3W2VB 3GYQA 3NK7A 4UY88 3IC6A 4MCCA 3BBEA 3N4KA 3KTYA 3OIJA 4MCBA 4JYZA 4YQAA 5FAIA 4YQPA 4WFNS 1ZJWA 3N4JA 4CNFA 2PICA 3AIIA 5GM8A 1UDXA 1X7OA 5JVHS 3KNUA 4P2BA 4H3ZA 1EUYA 1NS5A
chains in the Genus database with same CATH topology
2QWVA 5CO4A 1J85A 4YPYA 2EGWA 4MCDA 1MXIA 3OIIA 2O3AA 1V2XA 2QMMA 4YQKA 1GZ0A 1K3RA 4YQSA 1Z85A 4YQBA 4YVKA 1VH0A 4CNEA 5GMBA 3AI9X 3KW2A 3DCMX 2HA8A 4JALA 1O6DA 4YQ1A 4IG6A 2YY8A 3E5YA 4JWFA 4YQ3A 1V6ZA 4YQNA 4YVIA 4L69A 2V3JA 1VHYA 1P9PA 4YQ7A 4YQOA 4JAKA 4XBOA 2EGVA 4YQCA 3QUVA 4YQ8A 4RG1A 4YQQA 2CX8A 1TO0A 4JWJA 4YPXA 2Z0YA 4YQTA 1OY5A 4YQ2A 3NK6A 2I6DA 2NWAA 4YVJA 1IPAA 3AIAA 1X7PA 4FMWA 4YQGA 4YQDA 4JWGA 4YPWA 4J3CA 3O7BA 4CNDA 4YQLA 3AXZA 3BBDA 4KDZA 1ZJRA 1UAJA 3KY7A 3OINA 4E8BA 3ONPA 4X3MA 4YQ5A 3IEFA 4KGNA 1UALA 1UAMA 1NXZA 4YQ4A 4YQ0A 3ILKA 4YVHA 4YQ6A 1VHKA 5GMCA 4YQIA 4CNGA 4PZKA 4YVGA 5D9FA 4YPZA 4FAKA 4X3LA 3L8UA 4H3YA 4YQRA 2V3KA 3BBHA 4JWHA 1UAKA 4YQJA 3GYQA 3NK7A 3IC6A 4MCCA 3BBEA 3N4KA 3KTYA 3OIJA 4MCBA 4YQAA 5FAIA 4YQPA 4CNFA 3N4JA 5GM8A 1X7OA 3KNUA 4YQ9A 4H3ZA 1NS5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QWV A;  5CO4 A;  1J85 A;  4YPY A;  2EGW A;  4MCD A;  1MXI A;  3OII A;  2O3A A;  1V2X A;  2QMM A;  4YQK A;  1GZ0 A;  1K3R A;  4YQS A;  1Z85 A;  4YQB A;  4YVK A;  1VH0 A;  4CNE A;  5GMB A;  3AI9 X;  3KW2 A;  3DCM X;  2HA8 A;  4JAL A;  1O6D A;  4YQ1 A;  4IG6 A;  2YY8 A;  3E5Y A;  4YQ3 A;  1V6Z A;  4YQN A;  4YVI A;  4L69 A;  2V3J A;  1VHY A;  1P9P A;  4YQ7 A;  4YQO A;  4JAK A;  4XBO A;  2EGV A;  4YQC A;  3QUV A;  4YQ8 A;  4RG1 A;  4YQQ A;  2CX8 A;  1TO0 A;  4YPX A;  2Z0Y A;  4YQT A;  1OY5 A;  4YQ2 A;  3NK6 A;  2I6D A;  2NWA A;  4YVJ A;  1IPA A;  3AIA A;  1X7P A;  4YQG A;  4YQD A;  4YPW A;  4J3C A;  3O7B A;  4CND A;  4YQL A;  3AXZ A;  3BBD A;  4KDZ A;  1ZJR A;  1UAJ A;  3KY7 A;  3OIN A;  4E8B A;  3ONP A;  4X3M A;  4YQ5 A;  3IEF A;  4KGN A;  1UAL A;  1UAM A;  1NXZ A;  4YQ4 A;  4YQ0 A;  3ILK A;  4YVH A;  4YQ6 A;  1VHK A;  5GMC A;  4YQI A;  4CNG A;  4PZK A;  4YVG A;  5D9F A;  4YPZ A;  4FAK A;  4X3L A;  3L8U A;  4H3Y A;  4YQR A;  2V3K A;  3BBH A;  1UAK A;  4YQJ A;  3GYQ A;  3NK7 A;  3IC6 A;  4MCC A;  3BBE A;  3N4K A;  3KTY A;  3OIJ A;  4MCB A;  4YQA A;  5FAI A;  4YQP A;  4CNF A;  3N4J A;  5GM8 A;  1X7O A;  3KNU A;  4YQ9 A;  4H3Z A;  1NS5 A; 
#chains in the Genus database with same CATH topology
 2QWV A;  5CO4 A;  1J85 A;  4YPY A;  2EGW A;  4MCD A;  1MXI A;  5GAD W;  5GAG W;  3OII A;  3CZB A;  2O3A A;  1V2X A;  2G6G A;  4JXZ A;  2QMM A;  4WCE S;  4YQK A;  1GZ0 A;  1K3R A;  2HZ7 A;  4YQS A;  1Z85 A;  1QRU A;  4YQB A;  4YQ9 A;  4YVK A;  1VH0 A;  1DFU P;  1QTQ A;  1FEU A;  2ZJQ S;  4CNE A;  5GMB A;  4WFA S;  2GAE A;  3AI9 X;  3KW2 A;  3DCM X;  2HA8 A;  4JAL A;  1O6D A;  4YQ1 A;  4U67 S;  4IG6 A;  1QRT A;  2YY8 A;  3E5Y A;  4JWF A;  5GAH W;  4YQ3 A;  5DM7 S;  1V6Z A;  2PNW A;  4JXX A;  4YQN A;  2AE0 X;  4YVI A;  4L69 A;  2PI8 A;  5IZN A;  1VHY A;  3X1L B;  1P9P A;  2V3J A;  4YQ7 A;  4YQO A;  4JAK A;  2ZJP S;  4XBO A;  2EGV A;  2PJJ A;  4YQC A;  4WFB S;  3QUV A;  4YQ8 A;  4RG1 A;  4YQQ A;  2CX8 A;  1TO0 A;  4JWJ A;  4YPX A;  2Z0Y A;  4YQT A;  1OY5 A;  4YQ2 A;  3NK6 A;  2RD2 A;  2I6D A;  2NWA A;  4YVJ A;  3J7Z V;  4IOC S;  1IPA A;  3AIA A;  1X7P A;  4FMW A;  4YQG A;  4YQD A;  4JWG A;  4YPW A;  4J3C A;  3CF5 S;  3O7B A;  4H3S A;  1O0C A;  2ZJR S;  4YQL A;  4CND A;  1NYL A;  3AXZ A;  3BBD A;  4KDZ A;  1ZJR A;  1UAJ A;  3KY7 A;  5BNZ A;  1GTR A;  1D6K A;  3OIN A;  4E8B A;  3ONP A;  3W2W B;  4X3M A;  4YQ5 A;  2G5D A;  3IEF A;  4KGN A;  1UAL A;  4IOA S;  1UAM A;  1NXZ A;  4YQ4 A;  4YQ0 A;  3ILK A;  4YVH A;  4H4K A;  4YQ6 A;  1VHK A;  5GMC A;  1GTS A;  4YQI A;  4CNG A;  4WF9 S;  1EXD A;  4PZK A;  4YVG A;  5D9F A;  5DM6 S;  4YPZ A;  5GAE W;  4FAK A;  4V19 4;  3DLL S;  2RE8 A;  5HL7 S;  4X3L A;  1EUQ A;  3L8U A;  4H3Y A;  1O0B A;  3PIO S;  4YQR A;  2V3K A;  3BBH A;  3PIP S;  1B75 A;  4JWH A;  5JVG S;  4IO9 S;  1QRS A;  1UAK A;  4YQJ A;  3W2V B;  3GYQ A;  3NK7 A;  4UY8 8;  3IC6 A;  4MCC A;  3BBE A;  3N4K A;  3KTY A;  3OIJ A;  4MCB A;  4JYZ A;  4YQA A;  5FAI A;  4YQP A;  4WFN S;  1ZJW A;  3N4J A;  4CNF A;  2PIC A;  3AII A;  5GM8 A;  1UDX A;  1X7O A;  5JVH S;  3KNU A;  4P2B A;  4H3Z A;  1EUY A;  1NS5 A; 
#chains in the Genus database with same CATH homology
 2QWV A;  5CO4 A;  1J85 A;  4YPY A;  2EGW A;  4MCD A;  1MXI A;  3OII A;  2O3A A;  1V2X A;  2QMM A;  4YQK A;  1GZ0 A;  1K3R A;  4YQS A;  1Z85 A;  4YQB A;  4YVK A;  1VH0 A;  4CNE A;  5GMB A;  3AI9 X;  3KW2 A;  3DCM X;  2HA8 A;  4JAL A;  1O6D A;  4YQ1 A;  4IG6 A;  2YY8 A;  3E5Y A;  4JWF A;  4YQ3 A;  1V6Z A;  4YQN A;  4YVI A;  4L69 A;  2V3J A;  1VHY A;  1P9P A;  4YQ7 A;  4YQO A;  4JAK A;  4XBO A;  2EGV A;  4YQC A;  3QUV A;  4YQ8 A;  4RG1 A;  4YQQ A;  2CX8 A;  1TO0 A;  4JWJ A;  4YPX A;  2Z0Y A;  4YQT A;  1OY5 A;  4YQ2 A;  3NK6 A;  2I6D A;  2NWA A;  4YVJ A;  1IPA A;  3AIA A;  1X7P A;  4FMW A;  4YQG A;  4YQD A;  4JWG A;  4YPW A;  4J3C A;  3O7B A;  4CND A;  4YQL A;  3AXZ A;  3BBD A;  4KDZ A;  1ZJR A;  1UAJ A;  3KY7 A;  3OIN A;  4E8B A;  3ONP A;  4X3M A;  4YQ5 A;  3IEF A;  4KGN A;  1UAL A;  1UAM A;  1NXZ A;  4YQ4 A;  4YQ0 A;  3ILK A;  4YVH A;  4YQ6 A;  1VHK A;  5GMC A;  4YQI A;  4CNG A;  4PZK A;  4YVG A;  5D9F A;  4YPZ A;  4FAK A;  4X3L A;  3L8U A;  4H3Y A;  4YQR A;  2V3K A;  3BBH A;  4JWH A;  1UAK A;  4YQJ A;  3GYQ A;  3NK7 A;  3IC6 A;  4MCC A;  3BBE A;  3N4K A;  3KTY A;  3OIJ A;  4MCB A;  4YQA A;  5FAI A;  4YQP A;  4CNF A;  3N4J A;  5GM8 A;  1X7O A;  3KNU A;  4YQ9 A;  4H3Z A;  1NS5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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