4E8BA

Crystal structure of 16s rrna methyltransferase rsme from e.coli
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
242
structure length
242
Chain Sequence
IPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWCAEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFGDLGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 72
structure length 242
sequence length 242
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2012-03-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4e8bA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4e8bA02
4YQLA 3N4KA 2QMMA 2V3KA 3QUVA 1IPAA 3AI9X 3L8UA 3BBDA 4YPYA 1Z85A 4CNDA 4YQPA 4YQ0A 4YQNA 4J3CA 3IC6A 5GMBA 3GYQA 2CX8A 3ILKA 1O6DA 1GZ0A 3DCMX 4YQ9A 1UAKA 4YQIA 1VHKA 1P9PA 4IG6A 3OIJA 2EGWA 4YQAA 4YQKA 1J85A 4E8BA 3O7BA 3NK6A 1TO0A 4YQSA 4H3YA 4YVHA 5GM8A 5D9FA 5GMCA 4YQDA 1VH0A 3BBHA 1UAMA 4JAKA 4YQOA 2NWAA 4XBOA 4YQBA 1MXIA 3N4JA 2O3AA 4YPWA 4YPXA 4YQ1A 4MCBA 4YQ2A 4YQ7A 3BBEA 4X3LA 2QWVA 4YQGA 2EGVA 3KY7A 3KTYA 4YVJA 4PZKA 1V6ZA 4YQ3A 2YY8A 4CNFA 4YPZA 4MCCA 3AIAA 1UAJA 2HA8A 3E5YA 1V2XA 1X7OA 4H3ZA 3KNUA 1OY5A 4YQ5A 1NS5A 1X7PA 4FAKA 3KW2A 4YQRA 4YQTA 4YVIA 4CNGA 4YVKA 2Z0YA 3NK7A 4YQJA 4JALA 5FAIA 4KGNA 4L69A 4YQ6A 1NXZA 2I6DA 1K3RA 3OINA 3IEFA 5CO4A 4YQ8A 4CNEA 2V3JA 4X3MA 1ZJRA 4YQQA 3OIIA 4RG1A 4YVGA 1UALA 3ONPA 3AXZA 4MCDA 4YQ4A 1VHYA 4KDZA 4YQCA
chains in the Genus database with same CATH superfamily
4YQLA 3N4KA 2QMMA 2V3KA 3QUVA 5DM6S 1IPAA 4JWJA 3AI9X 3L8UA 3BBDA 4YPYA 4JWGA 1Z85A 2G6GA 4CNDA 4YQPA 4YQ0A 3J7ZV 4YQNA 2AE0X 2PNWA 4J3CA 5GAHW 4U67S 3IC6A 4JWFA 1O0BA 5GMBA 3GYQA 2CX8A 5JVHS 1GTSA 3ILKA 5GAEW 1GZ0A 1O6DA 1O0CA 4WCES 1UAKA 3DCMX 4YQ9A 4YQIA 1QRSA 1VHKA 1P9PA 4IG6A 3OIJA 2EGWA 5HL7S 1DFUP 4YQAA 4YQKA 1J85A 4E8BA 3NK6A 1D6KA 1TO0A 3O7BA 4YQSA 4H3YA 4WFBS 4YVHA 2PI8A 3CF5S 5GM8A 5JVGS 5D9FA 5GMCA 4YQDA 1VH0A 3BBHA 1UAMA 4JAKA 4YQOA 2NWAA 4XBOA 4YQBA 4IOCS 1MXIA 1ZJWA 3PIPS 3N4JA 2O3AA 4YPWA 1B75A 4YPXA 1QRUA 4YQ1A 5DM7S 4MCBA 4YQ2A 3PIOS 3DLLS 4YQ7A 5GAGW 3BBEA 4X3LA 2QWVA 4P2BA 4WF9S 4YQGA 2EGVA 3KY7A 3KTYA 4YVJA 4PZKA 1V6ZA 2GAEA 4YQ3A 1QTQA 2YY8A 1GTRA 4CNFA 5IZNA 1EUYA 2PJJA 4YPZA 1QRTA 4UY88 4MCCA 4WFNS 3AIAA 1UAJA 4V194 4JXZA 2HA8A 3E5YA 1V2XA 1X7OA 4H3ZA 4H4KA 1NYLA 2HZ7A 3KNUA 4IOAS 1OY5A 4YQ5A 3AIIA 2RE8A 1NS5A 1X7PA 4FAKA 3KW2A 4YQRA 1EXDA 4YQTA 4YVIA 4WFAS 4JWHA 3W2VB 3CZBA 4FMWA 4CNGA 4YVKA 2Z0YA 3W2WB 3NK7A 4JALA 4YQJA 5FAIA 2G5DA 4JYZA 4KGNA 2PICA 2ZJQS 4L69A 4YQ6A 2RD2A 3X1LB 1NXZA 2I6DA 1EUQA 5GADW 1K3RA 3IEFA 3OINA 1FEUA 5CO4A 4H3SA 4JXXA 4YQ8A 4CNEA 2ZJRS 2V3JA 4X3MA 1ZJRA 4YQQA 5BNZA 3OIIA 4RG1A 2ZJPS 4YVGA 1UALA 3ONPA 3AXZA 4MCDA 4YQ4A 4IO9S 1UDXA 1VHYA 4KDZA 4YQCA
chains in the Genus database with same CATH topology
4YQLA 3N4KA 2QMMA 2V3KA 3QUVA 1IPAA 4JWJA 3AI9X 3L8UA 3BBDA 4YPYA 4JWGA 1Z85A 4CNDA 4YQPA 4YQ0A 4YQNA 4J3CA 3IC6A 4JWFA 5GMBA 3GYQA 2CX8A 3ILKA 1O6DA 1GZ0A 3DCMX 4YQ9A 1UAKA 4YQIA 1VHKA 1P9PA 4IG6A 3OIJA 2EGWA 4YQAA 4YQKA 1J85A 4E8BA 3O7BA 3NK6A 1TO0A 4YQSA 4H3YA 4YVHA 5GM8A 5D9FA 5GMCA 4YQDA 1VH0A 3BBHA 1UAMA 4JAKA 4YQOA 2NWAA 4XBOA 4YQBA 1MXIA 3N4JA 2O3AA 4YPWA 4YPXA 4YQ1A 4MCBA 4YQ2A 4YQ7A 3BBEA 4X3LA 2QWVA 4YQGA 2EGVA 3KY7A 3KTYA 4YVJA 4PZKA 1V6ZA 4YQ3A 2YY8A 4CNFA 4YPZA 4MCCA 3AIAA 1UAJA 2HA8A 3E5YA 1V2XA 1X7OA 4H3ZA 3KNUA 1OY5A 4YQ5A 1NS5A 1X7PA 4FAKA 3KW2A 4YQRA 4YQTA 4YVIA 4JWHA 4FMWA 4CNGA 4YVKA 2Z0YA 3NK7A 4YQJA 4JALA 5FAIA 4KGNA 4L69A 4YQ6A 1NXZA 2I6DA 1K3RA 3OINA 3IEFA 5CO4A 4YQ8A 4CNEA 2V3JA 4X3MA 1ZJRA 4YQQA 3OIIA 4RG1A 4YVGA 1UALA 3ONPA 3AXZA 4MCDA 4YQ4A 1VHYA 4KDZA 4YQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQL A;  3N4K A;  2QMM A;  2V3K A;  3QUV A;  1IPA A;  3AI9 X;  3L8U A;  3BBD A;  4YPY A;  1Z85 A;  4CND A;  4YQP A;  4YQ0 A;  4YQN A;  4J3C A;  3IC6 A;  5GMB A;  3GYQ A;  2CX8 A;  3ILK A;  1O6D A;  1GZ0 A;  3DCM X;  4YQ9 A;  1UAK A;  4YQI A;  1VHK A;  1P9P A;  4IG6 A;  3OIJ A;  2EGW A;  4YQA A;  4YQK A;  1J85 A;  4E8B A;  3O7B A;  3NK6 A;  1TO0 A;  4YQS A;  4H3Y A;  4YVH A;  5GM8 A;  5D9F A;  5GMC A;  4YQD A;  1VH0 A;  3BBH A;  1UAM A;  4JAK A;  4YQO A;  2NWA A;  4XBO A;  4YQB A;  1MXI A;  3N4J A;  2O3A A;  4YPW A;  4YPX A;  4YQ1 A;  4MCB A;  4YQ2 A;  4YQ7 A;  3BBE A;  4X3L A;  2QWV A;  4YQG A;  2EGV A;  3KY7 A;  3KTY A;  4YVJ A;  4PZK A;  1V6Z A;  4YQ3 A;  2YY8 A;  4CNF A;  4YPZ A;  4MCC A;  3AIA A;  1UAJ A;  2HA8 A;  3E5Y A;  1V2X A;  1X7O A;  4H3Z A;  3KNU A;  1OY5 A;  4YQ5 A;  1NS5 A;  1X7P A;  4FAK A;  3KW2 A;  4YQR A;  4YQT A;  4YVI A;  4CNG A;  4YVK A;  2Z0Y A;  3NK7 A;  4YQJ A;  4JAL A;  5FAI A;  4KGN A;  4L69 A;  4YQ6 A;  1NXZ A;  2I6D A;  1K3R A;  3OIN A;  3IEF A;  5CO4 A;  4YQ8 A;  4CNE A;  2V3J A;  4X3M A;  1ZJR A;  4YQQ A;  3OII A;  4RG1 A;  4YVG A;  1UAL A;  3ONP A;  3AXZ A;  4MCD A;  4YQ4 A;  1VHY A;  4KDZ A;  4YQC A; 
#chains in the Genus database with same CATH topology
 4YQL A;  3N4K A;  2QMM A;  2V3K A;  3QUV A;  5DM6 S;  1IPA A;  4JWJ A;  3AI9 X;  3L8U A;  3BBD A;  4YPY A;  4JWG A;  1Z85 A;  2G6G A;  4CND A;  4YQP A;  4YQ0 A;  3J7Z V;  4YQN A;  2AE0 X;  2PNW A;  4J3C A;  5GAH W;  4U67 S;  3IC6 A;  4JWF A;  1O0B A;  5GMB A;  3GYQ A;  2CX8 A;  5JVH S;  1GTS A;  3ILK A;  5GAE W;  1GZ0 A;  1O6D A;  1O0C A;  4WCE S;  1UAK A;  3DCM X;  4YQ9 A;  4YQI A;  1QRS A;  1VHK A;  1P9P A;  4IG6 A;  3OIJ A;  2EGW A;  5HL7 S;  1DFU P;  4YQA A;  4YQK A;  1J85 A;  4E8B A;  3NK6 A;  1D6K A;  1TO0 A;  3O7B A;  4YQS A;  4H3Y A;  4WFB S;  4YVH A;  2PI8 A;  3CF5 S;  5GM8 A;  5JVG S;  5D9F A;  5GMC A;  4YQD A;  1VH0 A;  3BBH A;  1UAM A;  4JAK A;  4YQO A;  2NWA A;  4XBO A;  4YQB A;  4IOC S;  1MXI A;  1ZJW A;  3PIP S;  3N4J A;  2O3A A;  4YPW A;  1B75 A;  4YPX A;  1QRU A;  4YQ1 A;  5DM7 S;  4MCB A;  4YQ2 A;  3PIO S;  3DLL S;  4YQ7 A;  5GAG W;  3BBE A;  4X3L A;  2QWV A;  4P2B A;  4WF9 S;  4YQG A;  2EGV A;  3KY7 A;  3KTY A;  4YVJ A;  4PZK A;  1V6Z A;  2GAE A;  4YQ3 A;  1QTQ A;  2YY8 A;  1GTR A;  4CNF A;  5IZN A;  1EUY A;  2PJJ A;  4YPZ A;  1QRT A;  4UY8 8;  4MCC A;  4WFN S;  3AIA A;  1UAJ A;  4V19 4;  4JXZ A;  2HA8 A;  3E5Y A;  1V2X A;  1X7O A;  4H3Z A;  4H4K A;  1NYL A;  2HZ7 A;  3KNU A;  4IOA S;  1OY5 A;  4YQ5 A;  3AII A;  2RE8 A;  1NS5 A;  1X7P A;  4FAK A;  3KW2 A;  4YQR A;  1EXD A;  4YQT A;  4YVI A;  4WFA S;  4JWH A;  3W2V B;  3CZB A;  4FMW A;  4CNG A;  4YVK A;  2Z0Y A;  3W2W B;  3NK7 A;  4JAL A;  4YQJ A;  5FAI A;  2G5D A;  4JYZ A;  4KGN A;  2PIC A;  2ZJQ S;  4L69 A;  4YQ6 A;  2RD2 A;  3X1L B;  1NXZ A;  2I6D A;  1EUQ A;  5GAD W;  1K3R A;  3IEF A;  3OIN A;  1FEU A;  5CO4 A;  4H3S A;  4JXX A;  4YQ8 A;  4CNE A;  2ZJR S;  2V3J A;  4X3M A;  1ZJR A;  4YQQ A;  5BNZ A;  3OII A;  4RG1 A;  2ZJP S;  4YVG A;  1UAL A;  3ONP A;  3AXZ A;  4MCD A;  4YQ4 A;  4IO9 S;  1UDX A;  1VHY A;  4KDZ A;  4YQC A; 
#chains in the Genus database with same CATH homology
 4YQL A;  3N4K A;  2QMM A;  2V3K A;  3QUV A;  1IPA A;  4JWJ A;  3AI9 X;  3L8U A;  3BBD A;  4YPY A;  4JWG A;  1Z85 A;  4CND A;  4YQP A;  4YQ0 A;  4YQN A;  4J3C A;  3IC6 A;  4JWF A;  5GMB A;  3GYQ A;  2CX8 A;  3ILK A;  1O6D A;  1GZ0 A;  3DCM X;  4YQ9 A;  1UAK A;  4YQI A;  1VHK A;  1P9P A;  4IG6 A;  3OIJ A;  2EGW A;  4YQA A;  4YQK A;  1J85 A;  4E8B A;  3O7B A;  3NK6 A;  1TO0 A;  4YQS A;  4H3Y A;  4YVH A;  5GM8 A;  5D9F A;  5GMC A;  4YQD A;  1VH0 A;  3BBH A;  1UAM A;  4JAK A;  4YQO A;  2NWA A;  4XBO A;  4YQB A;  1MXI A;  3N4J A;  2O3A A;  4YPW A;  4YPX A;  4YQ1 A;  4MCB A;  4YQ2 A;  4YQ7 A;  3BBE A;  4X3L A;  2QWV A;  4YQG A;  2EGV A;  3KY7 A;  3KTY A;  4YVJ A;  4PZK A;  1V6Z A;  4YQ3 A;  2YY8 A;  4CNF A;  4YPZ A;  4MCC A;  3AIA A;  1UAJ A;  2HA8 A;  3E5Y A;  1V2X A;  1X7O A;  4H3Z A;  3KNU A;  1OY5 A;  4YQ5 A;  1NS5 A;  1X7P A;  4FAK A;  3KW2 A;  4YQR A;  4YQT A;  4YVI A;  4JWH A;  4FMW A;  4CNG A;  4YVK A;  2Z0Y A;  3NK7 A;  4YQJ A;  4JAL A;  5FAI A;  4KGN A;  4L69 A;  4YQ6 A;  1NXZ A;  2I6D A;  1K3R A;  3OIN A;  3IEF A;  5CO4 A;  4YQ8 A;  4CNE A;  2V3J A;  4X3M A;  1ZJR A;  4YQQ A;  3OII A;  4RG1 A;  4YVG A;  1UAL A;  3ONP A;  3AXZ A;  4MCD A;  4YQ4 A;  1VHY A;  4KDZ A;  4YQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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