4L69A

Rv2372c of mycobacterium tuberculosis is rsme like methyltransferse
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
247
structure length
244
Chain Sequence
VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 66
structure length 244
sequence length 247
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4l69A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4l69A02
5GMBA 2V3JA 4YQ6A 3KTYA 4JALA 5D9FA 1NXZA 1UAMA 4YQ5A 1UAKA 3IC6A 4YQSA 2Z0YA 3KY7A 1GZ0A 3OINA 5FAIA 2CX8A 4CNEA 4YVGA 4E8BA 1K3RA 1VHYA 4YQ9A 4KGNA 5CO4A 3DCMX 4YQRA 4YQQA 3OIIA 4YPYA 4YPXA 4MCBA 1VH0A 4YQJA 4L69A 4YQNA 4CNDA 1NS5A 1V2XA 1TO0A 3AIAA 4MCCA 4YQ2A 2V3KA 4JAKA 3ILKA 4YQ4A 4RG1A 4YQIA 1Z85A 3OIJA 4YQ3A 4H3ZA 3NK6A 4YQKA 2EGWA 4PZKA 2EGVA 4YQPA 1OY5A 3BBEA 3GYQA 1VHKA 4YQDA 4YVIA 4XBOA 2NWAA 3QUVA 4X3MA 5GMCA 4YVKA 1ZJRA 4YQGA 4YQTA 1UALA 3N4KA 1P9PA 1O6DA 2QWVA 4X3LA 4YQBA 1J85A 4MCDA 1X7OA 4YQ8A 4YPZA 3KW2A 3KNUA 3AXZA 4YPWA 4YQ7A 4YQ1A 4IG6A 3BBHA 3E5YA 4CNGA 1MXIA 4YVJA 2YY8A 1UAJA 3BBDA 4YQAA 4YQCA 3NK7A 3O7BA 4YVHA 2O3AA 3L8UA 4KDZA 2QMMA 4YQ0A 4YQOA 2I6DA 3AI9X 4FAKA 3N4JA 5GM8A 1IPAA 4H3YA 3ONPA 1V6ZA 2HA8A 1X7PA 4CNFA 4YQLA 4J3CA 3IEFA
chains in the Genus database with same CATH superfamily
5GMBA 1ZJWA 5GAEW 2V3JA 4UY88 3X1LB 4YQ6A 3KTYA 3DLLS 4JALA 4P2BA 5D9FA 1NXZA 1UAMA 4YQ5A 1UAKA 3IC6A 3PIPS 4JXXA 4YQSA 2Z0YA 4V194 4U67S 3KY7A 1GZ0A 3OINA 4JWJA 5FAIA 2CX8A 4CNEA 4YVGA 3CF5S 4E8BA 2GAEA 1K3RA 1VHYA 4YQ9A 4KGNA 2G6GA 5CO4A 4WFAS 2RD2A 2PJJA 2ZJQS 3DCMX 4YQRA 4YQQA 3OIIA 4YPYA 2PICA 1EUQA 4YPXA 4MCBA 1VH0A 4YQJA 4L69A 4YQNA 5JVGS 4CNDA 1NS5A 1V2XA 1TO0A 3AIAA 4MCCA 4YQ2A 2V3KA 5HL7S 4JAKA 3W2WB 3ILKA 4YQ4A 4WFBS 4RG1A 4YQIA 1Z85A 5IZNA 3OIJA 4YQ3A 1EUYA 4JXZA 4H3ZA 1QTQA 4JYZA 4IOCS 3NK6A 4YQKA 2EGWA 1D6KA 4PZKA 2EGVA 4YQPA 1OY5A 3BBEA 4H4KA 3GYQA 1VHKA 4YQDA 4YVIA 4XBOA 3AIIA 1O0CA 1QRUA 2NWAA 3QUVA 2HZ7A 4X3MA 5GMCA 2G5DA 4YVKA 1ZJRA 4YQGA 4YQTA 5GAHW 1UALA 3N4KA 1P9PA 1O6DA 2RE8A 2QWVA 3CZBA 4WFNS 4WCES 1QRSA 1GTSA 2AE0X 4X3LA 4FMWA 1J85A 5GADW 4YQBA 4MCDA 2ZJRS 1X7OA 4YQ8A 1B75A 4YPZA 3KW2A 3AXZA 2ZJPS 3KNUA 4YPWA 4YQ7A 4IG6A 3BBHA 4YQ1A 3E5YA 4CNGA 1MXIA 4YVJA 2YY8A 1UDXA 1UAJA 2PI8A 1NYLA 3BBDA 4IOAS 4YQAA 4JWHA 4YQCA 3NK7A 3O7BA 4YVHA 4JWFA 2O3AA 5BNZA 3L8UA 1O0BA 2PNWA 5JVHS 2QMMA 4KDZA 4YQ0A 4YQOA 1FEUA 1GTRA 2I6DA 4WF9S 1QRTA 3AI9X 4IO9S 4JWGA 4H3SA 5DM6S 5DM7S 3N4JA 5GM8A 4FAKA 1EXDA 1IPAA 3W2VB 4H3YA 1DFUP 1V6ZA 2HA8A 3ONPA 1X7PA 5GAGW 4CNFA 4YQLA 4J3CA 3IEFA 3J7ZV 3PIOS
chains in the Genus database with same CATH topology
5GMBA 2V3JA 4YQ6A 3KTYA 4JALA 5D9FA 1NXZA 1UAMA 4YQ5A 1UAKA 3IC6A 4YQSA 2Z0YA 3KY7A 1GZ0A 3OINA 4JWJA 5FAIA 2CX8A 4CNEA 4YVGA 4E8BA 1K3RA 1VHYA 4YQ9A 4KGNA 5CO4A 3DCMX 4YQRA 4YQQA 3OIIA 4YPYA 4YPXA 4MCBA 1VH0A 4YQJA 4L69A 4YQNA 4CNDA 1NS5A 1V2XA 1TO0A 3AIAA 4MCCA 4YQ2A 2V3KA 4JAKA 3ILKA 4YQ4A 4RG1A 4YQIA 1Z85A 3OIJA 4YQ3A 4H3ZA 3NK6A 4YQKA 2EGWA 4PZKA 2EGVA 4YQPA 1OY5A 3BBEA 3GYQA 1VHKA 4YQDA 4YVIA 4XBOA 2NWAA 3QUVA 4X3MA 5GMCA 4YVKA 1ZJRA 4YQGA 4YQTA 1UALA 3N4KA 1P9PA 1O6DA 2QWVA 4X3LA 4FMWA 1J85A 4YQBA 4MCDA 1X7OA 4YQ8A 4YPZA 3KW2A 3KNUA 3AXZA 4YPWA 4YQ7A 4YQ1A 4IG6A 3BBHA 3E5YA 4CNGA 1MXIA 4YVJA 2YY8A 1UAJA 3BBDA 4YQAA 4JWHA 4YQCA 3NK7A 3O7BA 4YVHA 4JWFA 2O3AA 3L8UA 4KDZA 2QMMA 4YQ0A 4YQOA 2I6DA 3AI9X 4JWGA 4FAKA 3N4JA 5GM8A 1IPAA 4H3YA 3ONPA 1V6ZA 2HA8A 1X7PA 4CNFA 4YQLA 4J3CA 3IEFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GMB A;  2V3J A;  4YQ6 A;  3KTY A;  4JAL A;  5D9F A;  1NXZ A;  1UAM A;  4YQ5 A;  1UAK A;  3IC6 A;  4YQS A;  2Z0Y A;  3KY7 A;  1GZ0 A;  3OIN A;  5FAI A;  2CX8 A;  4CNE A;  4YVG A;  4E8B A;  1K3R A;  1VHY A;  4YQ9 A;  4KGN A;  5CO4 A;  3DCM X;  4YQR A;  4YQQ A;  3OII A;  4YPY A;  4YPX A;  4MCB A;  1VH0 A;  4YQJ A;  4L69 A;  4YQN A;  4CND A;  1NS5 A;  1V2X A;  1TO0 A;  3AIA A;  4MCC A;  4YQ2 A;  2V3K A;  4JAK A;  3ILK A;  4YQ4 A;  4RG1 A;  4YQI A;  1Z85 A;  3OIJ A;  4YQ3 A;  4H3Z A;  3NK6 A;  4YQK A;  2EGW A;  4PZK A;  2EGV A;  4YQP A;  1OY5 A;  3BBE A;  3GYQ A;  1VHK A;  4YQD A;  4YVI A;  4XBO A;  2NWA A;  3QUV A;  4X3M A;  5GMC A;  4YVK A;  1ZJR A;  4YQG A;  4YQT A;  1UAL A;  3N4K A;  1P9P A;  1O6D A;  2QWV A;  4X3L A;  4YQB A;  1J85 A;  4MCD A;  1X7O A;  4YQ8 A;  4YPZ A;  3KW2 A;  3KNU A;  3AXZ A;  4YPW A;  4YQ7 A;  4YQ1 A;  4IG6 A;  3BBH A;  3E5Y A;  4CNG A;  1MXI A;  4YVJ A;  2YY8 A;  1UAJ A;  3BBD A;  4YQA A;  4YQC A;  3NK7 A;  3O7B A;  4YVH A;  2O3A A;  3L8U A;  4KDZ A;  2QMM A;  4YQ0 A;  4YQO A;  2I6D A;  3AI9 X;  4FAK A;  3N4J A;  5GM8 A;  1IPA A;  4H3Y A;  3ONP A;  1V6Z A;  2HA8 A;  1X7P A;  4CNF A;  4YQL A;  4J3C A;  3IEF A; 
#chains in the Genus database with same CATH topology
 5GMB A;  1ZJW A;  5GAE W;  2V3J A;  4UY8 8;  3X1L B;  4YQ6 A;  3KTY A;  3DLL S;  4JAL A;  4P2B A;  5D9F A;  1NXZ A;  1UAM A;  4YQ5 A;  1UAK A;  3IC6 A;  3PIP S;  4JXX A;  4YQS A;  2Z0Y A;  4V19 4;  4U67 S;  3KY7 A;  1GZ0 A;  3OIN A;  4JWJ A;  5FAI A;  2CX8 A;  4CNE A;  4YVG A;  3CF5 S;  4E8B A;  2GAE A;  1K3R A;  1VHY A;  4YQ9 A;  4KGN A;  2G6G A;  5CO4 A;  4WFA S;  2RD2 A;  2PJJ A;  2ZJQ S;  3DCM X;  4YQR A;  4YQQ A;  3OII A;  4YPY A;  2PIC A;  1EUQ A;  4YPX A;  4MCB A;  1VH0 A;  4YQJ A;  4L69 A;  4YQN A;  5JVG S;  4CND A;  1NS5 A;  1V2X A;  1TO0 A;  3AIA A;  4MCC A;  4YQ2 A;  2V3K A;  5HL7 S;  4JAK A;  3W2W B;  3ILK A;  4YQ4 A;  4WFB S;  4RG1 A;  4YQI A;  1Z85 A;  5IZN A;  3OIJ A;  4YQ3 A;  1EUY A;  4JXZ A;  4H3Z A;  1QTQ A;  4JYZ A;  4IOC S;  3NK6 A;  4YQK A;  2EGW A;  1D6K A;  4PZK A;  2EGV A;  4YQP A;  1OY5 A;  3BBE A;  4H4K A;  3GYQ A;  1VHK A;  4YQD A;  4YVI A;  4XBO A;  3AII A;  1O0C A;  1QRU A;  2NWA A;  3QUV A;  2HZ7 A;  4X3M A;  5GMC A;  2G5D A;  4YVK A;  1ZJR A;  4YQG A;  4YQT A;  5GAH W;  1UAL A;  3N4K A;  1P9P A;  1O6D A;  2RE8 A;  2QWV A;  3CZB A;  4WFN S;  4WCE S;  1QRS A;  1GTS A;  2AE0 X;  4X3L A;  4FMW A;  1J85 A;  5GAD W;  4YQB A;  4MCD A;  2ZJR S;  1X7O A;  4YQ8 A;  1B75 A;  4YPZ A;  3KW2 A;  3AXZ A;  2ZJP S;  3KNU A;  4YPW A;  4YQ7 A;  4IG6 A;  3BBH A;  4YQ1 A;  3E5Y A;  4CNG A;  1MXI A;  4YVJ A;  2YY8 A;  1UDX A;  1UAJ A;  2PI8 A;  1NYL A;  3BBD A;  4IOA S;  4YQA A;  4JWH A;  4YQC A;  3NK7 A;  3O7B A;  4YVH A;  4JWF A;  2O3A A;  5BNZ A;  3L8U A;  1O0B A;  2PNW A;  5JVH S;  2QMM A;  4KDZ A;  4YQ0 A;  4YQO A;  1FEU A;  1GTR A;  2I6D A;  4WF9 S;  1QRT A;  3AI9 X;  4IO9 S;  4JWG A;  4H3S A;  5DM6 S;  5DM7 S;  3N4J A;  5GM8 A;  4FAK A;  1EXD A;  1IPA A;  3W2V B;  4H3Y A;  1DFU P;  1V6Z A;  2HA8 A;  3ONP A;  1X7P A;  5GAG W;  4CNF A;  4YQL A;  4J3C A;  3IEF A;  3J7Z V;  3PIO S; 
#chains in the Genus database with same CATH homology
 5GMB A;  2V3J A;  4YQ6 A;  3KTY A;  4JAL A;  5D9F A;  1NXZ A;  1UAM A;  4YQ5 A;  1UAK A;  3IC6 A;  4YQS A;  2Z0Y A;  3KY7 A;  1GZ0 A;  3OIN A;  4JWJ A;  5FAI A;  2CX8 A;  4CNE A;  4YVG A;  4E8B A;  1K3R A;  1VHY A;  4YQ9 A;  4KGN A;  5CO4 A;  3DCM X;  4YQR A;  4YQQ A;  3OII A;  4YPY A;  4YPX A;  4MCB A;  1VH0 A;  4YQJ A;  4L69 A;  4YQN A;  4CND A;  1NS5 A;  1V2X A;  1TO0 A;  3AIA A;  4MCC A;  4YQ2 A;  2V3K A;  4JAK A;  3ILK A;  4YQ4 A;  4RG1 A;  4YQI A;  1Z85 A;  3OIJ A;  4YQ3 A;  4H3Z A;  3NK6 A;  4YQK A;  2EGW A;  4PZK A;  2EGV A;  4YQP A;  1OY5 A;  3BBE A;  3GYQ A;  1VHK A;  4YQD A;  4YVI A;  4XBO A;  2NWA A;  3QUV A;  4X3M A;  5GMC A;  4YVK A;  1ZJR A;  4YQG A;  4YQT A;  1UAL A;  3N4K A;  1P9P A;  1O6D A;  2QWV A;  4X3L A;  4FMW A;  1J85 A;  4YQB A;  4MCD A;  1X7O A;  4YQ8 A;  4YPZ A;  3KW2 A;  3KNU A;  3AXZ A;  4YPW A;  4YQ7 A;  4YQ1 A;  4IG6 A;  3BBH A;  3E5Y A;  4CNG A;  1MXI A;  4YVJ A;  2YY8 A;  1UAJ A;  3BBD A;  4YQA A;  4JWH A;  4YQC A;  3NK7 A;  3O7B A;  4YVH A;  4JWF A;  2O3A A;  3L8U A;  4KDZ A;  2QMM A;  4YQ0 A;  4YQO A;  2I6D A;  3AI9 X;  4JWG A;  4FAK A;  3N4J A;  5GM8 A;  1IPA A;  4H3Y A;  3ONP A;  1V6Z A;  2HA8 A;  1X7P A;  4CNF A;  4YQL A;  4J3C A;  3IEF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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