4L69A

Rv2372c of mycobacterium tuberculosis is rsme like methyltransferse
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
247
structure length
244
Chain Sequence
VAMLFYVDTLPDTGAVAVVDGDEGFHAATVRRIRPGEQLVLGDGVGRLARCVVEQGGLRARVLRRWSVPPVRPPVTVVQALPKSERSELAIELATEAGADAFLAWQAARCVANWDGARVDKGLRRWRAVVRSAARQSRRARIPPVDGVLSTPMLVQRVREEVAAGAAVLVLHEEATERIVDIAAAQAGSLMLVVGPEGGIAPDELAALTDAGAVAVRLGPTVLRTSTAAAVALGAVGVLTSRWD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Ribosomal RNA small subunit methyltransferase E
total genus 66
structure length 244
sequence length 247
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2013-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 4l69A01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4l69A02
4JAKA 2I6DA 4X3LA 3KNUA 5FAIA 4J3CA 4YQRA 4YQDA 1UALA 1VHKA 4MCBA 4KDZA 1VHYA 3BBDA 4YQKA 1IPAA 4YQAA 4YVGA 2HA8A 2Z0YA 4YQ2A 4YQ9A 4L69A 4YVKA 2YY8A 4YQTA 5CO4A 4YQSA 3O7BA 5GMBA 4E8BA 4YVHA 1X7OA 2O3AA 4YPZA 1GZ0A 4XBOA 4YPWA 4H3ZA 1V2XA 2QWVA 4H3YA 4YQGA 2V3KA 1P9PA 3ILKA 4CNDA 4JALA 3BBHA 1OY5A 4YQ0A 4YQ6A 3OIIA 4YQJA 1UAJA 4KGNA 3ONPA 3KW2A 4YQCA 4YQQA 1O6DA 4YPYA 3AIAA 3AI9X 4YVIA 4YQ1A 4YVJA 4FAKA 3NK7A 3AXZA 2EGVA 1X7PA 1V6ZA 4YPXA 2QMMA 4PZKA 3OINA 3BBEA 4YQIA 4YQOA 3DCMX 1J85A 1Z85A 2EGWA 3IEFA 4YQLA 4CNFA 4YQPA 3QUVA 3N4JA 1K3RA 4MCDA 3NK6A 4YQ4A 1MXIA 2CX8A 4MCCA 1NXZA 4YQ7A 4YQBA 1UAKA 1NS5A 1UAMA 1VH0A 3KY7A 1ZJRA 4RG1A 4YQ3A 4YQ8A 4CNEA 3E5YA 3OIJA 4CNGA 3N4KA 3KTYA 4IG6A 4YQ5A 4YQNA 4X3MA 2V3JA 3IC6A 3L8UA 2NWAA 1TO0A 5GMCA 5GM8A 3GYQA 5D9FA
chains in the Genus database with same CATH superfamily
4WFAS 4JAKA 2I6DA 4X3LA 3KNUA 5FAIA 4J3CA 4YQRA 4YQDA 1UALA 4JWFA 1VHKA 3J7ZV 3X1LB 4MCBA 4KDZA 1VHYA 3BBDA 4YQKA 1IPAA 4YQAA 2PJJA 4IOCS 4YVGA 4JYZA 2HA8A 2Z0YA 4YQ2A 4YQ9A 2RD2A 1D6KA 4IOAS 4L69A 4YVKA 1GTSA 2YY8A 1NYLA 3PIPS 4YQTA 3PIOS 5GADW 5CO4A 4YQSA 5DM7S 1UDXA 3O7BA 2HZ7A 5GMBA 2AE0X 4E8BA 1FEUA 4YVHA 1X7OA 2O3AA 5JVGS 4JWGA 2PICA 4YPZA 1GZ0A 4XBOA 4YPWA 4H3ZA 4H3SA 4H4KA 3W2WB 4UY88 1V2XA 2QWVA 2V3KA 1P9PA 4H3YA 4WFBS 1EUQA 4YQGA 3ILKA 5GAEW 4CNDA 4JALA 3DLLS 3BBHA 3CF5S 1OY5A 4YQ0A 4YQ6A 3OIIA 4WF9S 1UAJA 4KGNA 4YQJA 4P2BA 3ONPA 2PI8A 3KW2A 5HL7S 4YQCA 5IZNA 2G5DA 4YQQA 1O6DA 4YPYA 3AIAA 4JWHA 3AI9X 4YVIA 2RE8A 4YQ1A 4YVJA 5GAHW 4FAKA 3NK7A 3AXZA 2EGVA 1X7PA 2ZJRS 1V6ZA 5DM6S 5JVHS 2QMMA 1GTRA 4PZKA 4YPXA 3OINA 3BBEA 1O0CA 1QRSA 4YQIA 4YQOA 3W2VB 3DCMX 1J85A 1Z85A 2EGWA 3IEFA 4YQLA 4JWJA 4CNFA 4JXXA 1EUYA 4YQPA 3QUVA 1QRTA 3N4JA 1K3RA 4MCDA 3NK6A 4YQ4A 4V194 1MXIA 4U67S 2CX8A 4MCCA 1NXZA 4YQ7A 4WFNS 1QTQA 4WCES 4YQBA 1UAKA 4IO9S 1B75A 4FMWA 1DFUP 1O0BA 1QRUA 1NS5A 2PNWA 1UAMA 1VH0A 3KY7A 5D9FA 1ZJRA 4RG1A 4YQ3A 4JXZA 2ZJQS 2ZJPS 4YQ8A 4CNEA 3E5YA 3OIJA 4CNGA 3N4KA 5BNZA 3KTYA 4IG6A 4YQ5A 3AIIA 2G6GA 4YQNA 5GAGW 1ZJWA 4X3MA 2V3JA 3IC6A 3L8UA 3CZBA 2NWAA 1TO0A 5GMCA 5GM8A 2GAEA 3GYQA 1EXDA
chains in the Genus database with same CATH topology
4JAKA 2I6DA 4X3LA 3KNUA 5FAIA 4J3CA 4YQRA 4YQDA 1UALA 4JWFA 1VHKA 4MCBA 4KDZA 1VHYA 3BBDA 4YQKA 1IPAA 4YQAA 4YVGA 2HA8A 2Z0YA 4YQ2A 4YQ9A 4L69A 4YVKA 2YY8A 4YQTA 5CO4A 4YQSA 3O7BA 5GMBA 4E8BA 4YVHA 1X7OA 2O3AA 4JWGA 4YPZA 1GZ0A 4XBOA 4YPWA 4H3ZA 1V2XA 2QWVA 4H3YA 4YQGA 2V3KA 1P9PA 3ILKA 4CNDA 4JALA 3BBHA 1OY5A 4YQ0A 4YQ6A 3OIIA 4YQJA 1UAJA 4KGNA 3ONPA 3KW2A 4YQCA 4YQQA 1O6DA 4YPYA 3AIAA 4JWHA 3AI9X 4YVIA 4YQ1A 4YVJA 4FAKA 3NK7A 3AXZA 2EGVA 1X7PA 1V6ZA 4YPXA 2QMMA 4PZKA 3OINA 3BBEA 4YQIA 4YQOA 3DCMX 1J85A 1Z85A 2EGWA 3IEFA 4YQLA 4JWJA 4CNFA 4YQPA 3QUVA 3N4JA 1K3RA 4MCDA 3NK6A 4YQ4A 1MXIA 2CX8A 4MCCA 1NXZA 4YQ7A 4YQBA 1UAKA 4FMWA 1NS5A 1UAMA 1VH0A 3KY7A 1ZJRA 4RG1A 4YQ3A 4YQ8A 4CNEA 3E5YA 3OIJA 4CNGA 3N4KA 3KTYA 4IG6A 4YQ5A 4YQNA 4X3MA 2V3JA 3IC6A 3L8UA 2NWAA 1TO0A 5GMCA 5GM8A 3GYQA 5D9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JAK A;  2I6D A;  4X3L A;  3KNU A;  5FAI A;  4J3C A;  4YQR A;  4YQD A;  1UAL A;  1VHK A;  4MCB A;  4KDZ A;  1VHY A;  3BBD A;  4YQK A;  1IPA A;  4YQA A;  4YVG A;  2HA8 A;  2Z0Y A;  4YQ2 A;  4YQ9 A;  4L69 A;  4YVK A;  2YY8 A;  4YQT A;  5CO4 A;  4YQS A;  3O7B A;  5GMB A;  4E8B A;  4YVH A;  1X7O A;  2O3A A;  4YPZ A;  1GZ0 A;  4XBO A;  4YPW A;  4H3Z A;  1V2X A;  2QWV A;  4H3Y A;  4YQG A;  2V3K A;  1P9P A;  3ILK A;  4CND A;  4JAL A;  3BBH A;  1OY5 A;  4YQ0 A;  4YQ6 A;  3OII A;  4YQJ A;  1UAJ A;  4KGN A;  3ONP A;  3KW2 A;  4YQC A;  4YQQ A;  1O6D A;  4YPY A;  3AIA A;  3AI9 X;  4YVI A;  4YQ1 A;  4YVJ A;  4FAK A;  3NK7 A;  3AXZ A;  2EGV A;  1X7P A;  1V6Z A;  4YPX A;  2QMM A;  4PZK A;  3OIN A;  3BBE A;  4YQI A;  4YQO A;  3DCM X;  1J85 A;  1Z85 A;  2EGW A;  3IEF A;  4YQL A;  4CNF A;  4YQP A;  3QUV A;  3N4J A;  1K3R A;  4MCD A;  3NK6 A;  4YQ4 A;  1MXI A;  2CX8 A;  4MCC A;  1NXZ A;  4YQ7 A;  4YQB A;  1UAK A;  1NS5 A;  1UAM A;  1VH0 A;  3KY7 A;  1ZJR A;  4RG1 A;  4YQ3 A;  4YQ8 A;  4CNE A;  3E5Y A;  3OIJ A;  4CNG A;  3N4K A;  3KTY A;  4IG6 A;  4YQ5 A;  4YQN A;  4X3M A;  2V3J A;  3IC6 A;  3L8U A;  2NWA A;  1TO0 A;  5GMC A;  5GM8 A;  3GYQ A;  5D9F A; 
#chains in the Genus database with same CATH topology
 4WFA S;  4JAK A;  2I6D A;  4X3L A;  3KNU A;  5FAI A;  4J3C A;  4YQR A;  4YQD A;  1UAL A;  4JWF A;  1VHK A;  3J7Z V;  3X1L B;  4MCB A;  4KDZ A;  1VHY A;  3BBD A;  4YQK A;  1IPA A;  4YQA A;  2PJJ A;  4IOC S;  4YVG A;  4JYZ A;  2HA8 A;  2Z0Y A;  4YQ2 A;  4YQ9 A;  2RD2 A;  1D6K A;  4IOA S;  4L69 A;  4YVK A;  1GTS A;  2YY8 A;  1NYL A;  3PIP S;  4YQT A;  3PIO S;  5GAD W;  5CO4 A;  4YQS A;  5DM7 S;  1UDX A;  3O7B A;  2HZ7 A;  5GMB A;  2AE0 X;  4E8B A;  1FEU A;  4YVH A;  1X7O A;  2O3A A;  5JVG S;  4JWG A;  2PIC A;  4YPZ A;  1GZ0 A;  4XBO A;  4YPW A;  4H3Z A;  4H3S A;  4H4K A;  3W2W B;  4UY8 8;  1V2X A;  2QWV A;  2V3K A;  1P9P A;  4H3Y A;  4WFB S;  1EUQ A;  4YQG A;  3ILK A;  5GAE W;  4CND A;  4JAL A;  3DLL S;  3BBH A;  3CF5 S;  1OY5 A;  4YQ0 A;  4YQ6 A;  3OII A;  4WF9 S;  1UAJ A;  4KGN A;  4YQJ A;  4P2B A;  3ONP A;  2PI8 A;  3KW2 A;  5HL7 S;  4YQC A;  5IZN A;  2G5D A;  4YQQ A;  1O6D A;  4YPY A;  3AIA A;  4JWH A;  3AI9 X;  4YVI A;  2RE8 A;  4YQ1 A;  4YVJ A;  5GAH W;  4FAK A;  3NK7 A;  3AXZ A;  2EGV A;  1X7P A;  2ZJR S;  1V6Z A;  5DM6 S;  5JVH S;  2QMM A;  1GTR A;  4PZK A;  4YPX A;  3OIN A;  3BBE A;  1O0C A;  1QRS A;  4YQI A;  4YQO A;  3W2V B;  3DCM X;  1J85 A;  1Z85 A;  2EGW A;  3IEF A;  4YQL A;  4JWJ A;  4CNF A;  4JXX A;  1EUY A;  4YQP A;  3QUV A;  1QRT A;  3N4J A;  1K3R A;  4MCD A;  3NK6 A;  4YQ4 A;  4V19 4;  1MXI A;  4U67 S;  2CX8 A;  4MCC A;  1NXZ A;  4YQ7 A;  4WFN S;  1QTQ A;  4WCE S;  4YQB A;  1UAK A;  4IO9 S;  1B75 A;  4FMW A;  1DFU P;  1O0B A;  1QRU A;  1NS5 A;  2PNW A;  1UAM A;  1VH0 A;  3KY7 A;  5D9F A;  1ZJR A;  4RG1 A;  4YQ3 A;  4JXZ A;  2ZJQ S;  2ZJP S;  4YQ8 A;  4CNE A;  3E5Y A;  3OIJ A;  4CNG A;  3N4K A;  5BNZ A;  3KTY A;  4IG6 A;  4YQ5 A;  3AII A;  2G6G A;  4YQN A;  5GAG W;  1ZJW A;  4X3M A;  2V3J A;  3IC6 A;  3L8U A;  3CZB A;  2NWA A;  1TO0 A;  5GMC A;  5GM8 A;  2GAE A;  3GYQ A;  1EXD A; 
#chains in the Genus database with same CATH homology
 4JAK A;  2I6D A;  4X3L A;  3KNU A;  5FAI A;  4J3C A;  4YQR A;  4YQD A;  1UAL A;  4JWF A;  1VHK A;  4MCB A;  4KDZ A;  1VHY A;  3BBD A;  4YQK A;  1IPA A;  4YQA A;  4YVG A;  2HA8 A;  2Z0Y A;  4YQ2 A;  4YQ9 A;  4L69 A;  4YVK A;  2YY8 A;  4YQT A;  5CO4 A;  4YQS A;  3O7B A;  5GMB A;  4E8B A;  4YVH A;  1X7O A;  2O3A A;  4JWG A;  4YPZ A;  1GZ0 A;  4XBO A;  4YPW A;  4H3Z A;  1V2X A;  2QWV A;  4H3Y A;  4YQG A;  2V3K A;  1P9P A;  3ILK A;  4CND A;  4JAL A;  3BBH A;  1OY5 A;  4YQ0 A;  4YQ6 A;  3OII A;  4YQJ A;  1UAJ A;  4KGN A;  3ONP A;  3KW2 A;  4YQC A;  4YQQ A;  1O6D A;  4YPY A;  3AIA A;  4JWH A;  3AI9 X;  4YVI A;  4YQ1 A;  4YVJ A;  4FAK A;  3NK7 A;  3AXZ A;  2EGV A;  1X7P A;  1V6Z A;  4YPX A;  2QMM A;  4PZK A;  3OIN A;  3BBE A;  4YQI A;  4YQO A;  3DCM X;  1J85 A;  1Z85 A;  2EGW A;  3IEF A;  4YQL A;  4JWJ A;  4CNF A;  4YQP A;  3QUV A;  3N4J A;  1K3R A;  4MCD A;  3NK6 A;  4YQ4 A;  1MXI A;  2CX8 A;  4MCC A;  1NXZ A;  4YQ7 A;  4YQB A;  1UAK A;  4FMW A;  1NS5 A;  1UAM A;  1VH0 A;  3KY7 A;  1ZJR A;  4RG1 A;  4YQ3 A;  4YQ8 A;  4CNE A;  3E5Y A;  3OIJ A;  4CNG A;  3N4K A;  3KTY A;  4IG6 A;  4YQ5 A;  4YQN A;  4X3M A;  2V3J A;  3IC6 A;  3L8U A;  2NWA A;  1TO0 A;  5GMC A;  5GM8 A;  3GYQ A;  5D9F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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