4MY4 | Genus

Total Genus 192

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	192
Knots found	KnotProt 2.0: S +3₁
sequence length	503
structure length	503
Chain Sequence	KKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Isomerase
source organism	Staphylococcus aureus subsp. aureus
publication title	Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism pubmed doi rcsb
molecule keywords	2,3-bisphosphoglycerate-independent phosphoglycerate mutase
total genus	192
structure length	503
sequence length	503
other databases	KnotProt 2.0: S +3₁
ec nomenclature	ec 5.4.2.1: Transferred entry: 5.4.2.11 and 5.4.2.12.
pdb deposition date	2013-09-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01676	Metalloenzyme	Metalloenzyme superfamily
A	PF06415	iPGM_N	BPG-independent PGAM N-terminus (iPGM_N)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.720.10	Alpha Beta	3-Layer(aba) Sandwich	Alkaline Phosphatase, subunit A	Alkaline Phosphatase, subunit A	4my4A01
3.40.1450.10	Alpha Beta	3-Layer(aba) Sandwich	2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	BPG-independent phosphoglycerate mutase, domain B	4my4A02

4LRBA 4LR2A 1ZEFA 4NWXA 2W5TA 3NKMA 4GTWA 2GA3A 4MHXA 3TWZA 3NKPA 5LIAA 1ALJA 4KAVA 1E2SP 1KH5A 5IJQA 2W8SA 1EW8A 5GOVA 3LXQA 2IUCA 2ZKTA 4LRAA 4ZG7A 4KJGA 1ALKA 4TN0A 2W5WA 4LRFA 5LQQA 3MK2A 3WAXA 2IUCB 3BDHA 3M8YA 3KD8A 5C66A 4LQYA 3UO0A 1KH7A 3TX0A 1SHQA 1ELXA 1ALHA 4CYRA 4UPHA 4ZG9A 1E33P 1KHJA 3NKRA 4GTYA 1KH9A 5LRNA 5DLTA 1K7HA 3ED4A 3T02A 1HDHA 3NKNA 2RH6A 3T01A 1E3CP 5DLWA 4CXKA 1Y7AA 3UNYA 4KM4A 1URAA 3IDDA 2X98A 3BDFA 4GTZA 3WAYA 3WAWA 4B56A 3M8WA 3UN3A 1AJDA 3NVLA 2XR9A 4UOPA 2QZUA 3DYCA 2W5SA 5HRTA 5IJSA 3T00A 5DLVA 1KHKA 1EW2A 1ANJA 4UOOA 3SZYA 5KXAA 1ED9A 2GSOA 3SZZA 1KHLA 4NWJA 1HQAA 4QAXA 5L0EA 1AJAA 1N2KA 1HJKA 3B5QA 4UPKA 2W5RA 4LR9A 4CXSA 2VQRA 1KH4A 1ALIA 4LR7A 5TJ3A 5L0BA 3A52A 4MIVA 4UPLA 4LRCA 3NKQA 2W5VA 1E1ZP 3IGZB 4LREA 4CXUA 2IFYA 1ZEBA 1URBA 5GRRA 3WAVA 2ANHA 3IGYB 1N2LA 3NKOA 4FDIA 5AJ9A 3MK0A 4LR8A 1EI6A 1ED8A 1P49A 1Y6VA 3WBHA 4LRDA 3OT9A 2GLQA 1AUKA 5INHA 5L0KA 4ZG6A 3TG0A 3MK1A 5K4PA 4N7TA 2W5XA 2G9YA 1AJBA 4FDJA 2W5QA 4GTXA 1ELZA 5LRMA 3UN5A 1AJCA 2W8DA 5EGHA 4CYSA 3CMRA 2GSNA 1ELYA 1SHNA 4MY4A 1ANIA 1EJJA 5EGEA 3BDGA 3DPCA 3E2DA 1KHNA 3M8ZA 2XRGA 4KJDA 2GSUA 4UPIA 1O98A 1FSUA 1O99A 4YR1A 3BDGB 2D1GA 4UORA 1B8JA 1EQJA 3UN2A 1ZEDA 4ZGAA 1EW9A 4KAYA 3Q3QA 3M7VA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4LRB A;  4LR2 A;  1ZEF A;  4NWX A;  2W5T A;  3NKM A;  4GTW A;  2GA3 A;  4MHX A;  3TWZ A;  3NKP A;  5LIA A;  1ALJ A;  4KAV A;  1E2S P;  1KH5 A;  5IJQ A;  2W8S A;  1EW8 A;  5GOV A;  3LXQ A;  2IUC A;  2ZKT A;  4LRA A;  4ZG7 A;  4KJG A;  1ALK A;  4TN0 A;  2W5W A;  4LRF A;  5LQQ A;  3MK2 A;  3WAX A;  2IUC B;  3BDH A;  3M8Y A;  3KD8 A;  5C66 A;  4LQY A;  3UO0 A;  1KH7 A;  3TX0 A;  1SHQ A;  1ELX A;  1ALH A;  4CYR A;  4UPH A;  4ZG9 A;  1E33 P;  1KHJ A;  3NKR A;  4GTY A;  1KH9 A;  5LRN A;  5DLT A;  1K7H A;  3ED4 A;  3T02 A;  1HDH A;  3NKN A;  2RH6 A;  3T01 A;  1E3C P;  5DLW A;  4CXK A;  1Y7A A;  3UNY A;  4KM4 A;  1URA A;  3IDD A;  2X98 A;  3BDF A;  4GTZ A;  3WAY A;  3WAW A;  4B56 A;  3M8W A;  3UN3 A;  1AJD A;  3NVL A;  2XR9 A;  4UOP A;  2QZU A;  3DYC A;  2W5S A;  5HRT A;  5IJS A;  3T00 A;  5DLV A;  1KHK A;  1EW2 A;  1ANJ A;  4UOO A;  3SZY A;  5KXA A;  1ED9 A;  2GSO A;  3SZZ A;  1KHL A;  4NWJ A;  1HQA A;  4QAX A;  5L0E A;  1AJA A;  1N2K A;  1HJK A;  3B5Q A;  4UPK A;  2W5R A;  4LR9 A;  4CXS A;  2VQR A;  1KH4 A;  1ALI A;  4LR7 A;  5TJ3 A;  5L0B A;  3A52 A;  4MIV A;  4UPL A;  4LRC A;  3NKQ A;  2W5V A;  1E1Z P;  3IGZ B;  4LRE A;  4CXU A;  2IFY A;  1ZEB A;  1URB A;  5GRR A;  3WAV A;  2ANH A;  3IGY B;  1N2L A;  3NKO A;  4FDI A;  5AJ9 A;  3MK0 A;  4LR8 A;  1EI6 A;  1ED8 A;  1P49 A;  1Y6V A;  3WBH A;  4LRD A;  3OT9 A;  2GLQ A;  1AUK A;  5INH A;  5L0K A;  4ZG6 A;  3TG0 A;  3MK1 A;  5K4P A;  4N7T A;  2W5X A;  2G9Y A;  1AJB A;  4FDJ A;  2W5Q A;  4GTX A;  1ELZ A;  5LRM A;  3UN5 A;  1AJC A;  2W8D A;  5EGH A;  4CYS A;  3CMR A;  2GSN A;  1ELY A;  1SHN A;  4MY4 A;  1ANI A;  1EJJ A;  5EGE A;  3BDG A;  3DPC A;  3E2D A;  1KHN A;  3M8Z A;  2XRG A;  4KJD A;  2GSU A;  4UPI A;  1O98 A;  1FSU A;  1O99 A;  4YR1 A;  3BDG B;  2D1G A;  4UOR A;  1B8J A;  1EQJ A;  3UN2 A;  1ZED A;  4ZGA A;  1EW9 A;  4KAY A;  3Q3Q A;  3M7V A; 
#chains in the Genus database with same CATH topology
 4LRB A;  4LR2 A;  1ZEF A;  4NWX A;  2W5T A;  3NKM A;  4GTW A;  2GA3 A;  4MHX A;  3TWZ A;  3NKP A;  5LIA A;  1ALJ A;  4KAV A;  1E2S P;  1KH5 A;  5IJQ A;  2W8S A;  1EW8 A;  5GOV A;  3LXQ A;  2IUC A;  2ZKT A;  4LRA A;  4ZG7 A;  4KJG A;  1ALK A;  4TN0 A;  2W5W A;  4LRF A;  5LQQ A;  3MK2 A;  3WAX A;  2IUC B;  3BDH A;  3M8Y A;  3KD8 A;  5C66 A;  4LQY A;  3UO0 A;  1KH7 A;  3TX0 A;  1SHQ A;  1ELX A;  1ALH A;  4CYR A;  4UPH A;  4ZG9 A;  1E33 P;  1KHJ A;  3NKR A;  4GTY A;  1KH9 A;  5LRN A;  5DLT A;  1K7H A;  3ED4 A;  3T02 A;  1HDH A;  3NKN A;  2RH6 A;  3T01 A;  1E3C P;  5DLW A;  4CXK A;  1Y7A A;  3UNY A;  4KM4 A;  1URA A;  3IDD A;  2X98 A;  3BDF A;  4GTZ A;  3WAY A;  3WAW A;  4B56 A;  3M8W A;  3UN3 A;  1AJD A;  3NVL A;  2XR9 A;  4UOP A;  2QZU A;  3DYC A;  2W5S A;  5HRT A;  5IJS A;  3T00 A;  5DLV A;  1KHK A;  1EW2 A;  1ANJ A;  4UOO A;  3SZY A;  5KXA A;  1ED9 A;  2GSO A;  3SZZ A;  1KHL A;  4NWJ A;  1HQA A;  4QAX A;  5L0E A;  1AJA A;  1N2K A;  1HJK A;  3B5Q A;  4UPK A;  2W5R A;  4LR9 A;  4CXS A;  2VQR A;  1KH4 A;  1ALI A;  4LR7 A;  5TJ3 A;  5L0B A;  3A52 A;  4MIV A;  4UPL A;  4LRC A;  3NKQ A;  2W5V A;  1E1Z P;  3IGZ B;  4LRE A;  4CXU A;  2IFY A;  1ZEB A;  1URB A;  5GRR A;  3WAV A;  2ANH A;  3IGY B;  1N2L A;  3NKO A;  4FDI A;  5AJ9 A;  3MK0 A;  4LR8 A;  1EI6 A;  1ED8 A;  1P49 A;  1Y6V A;  3WBH A;  4LRD A;  3OT9 A;  2GLQ A;  1AUK A;  5INH A;  5L0K A;  4ZG6 A;  3TG0 A;  3MK1 A;  5K4P A;  4N7T A;  2W5X A;  2G9Y A;  1AJB A;  4FDJ A;  2W5Q A;  4GTX A;  1ELZ A;  5LRM A;  3UN5 A;  1AJC A;  2W8D A;  5EGH A;  4CYS A;  3CMR A;  2GSN A;  1ELY A;  1SHN A;  4MY4 A;  1ANI A;  1EJJ A;  5EGE A;  3BDG A;  3DPC A;  3E2D A;  1KHN A;  3M8Z A;  2XRG A;  4KJD A;  2GSU A;  4UPI A;  1O98 A;  1FSU A;  1O99 A;  4YR1 A;  3BDG B;  2D1G A;  4UOR A;  1B8J A;  1EQJ A;  3UN2 A;  1ZED A;  4ZGA A;  1EW9 A;  4KAY A;  3Q3Q A;  3M7V A; 
#chains in the Genus database with same CATH homology
 4LRB A;  4LR2 A;  1ZEF A;  4NWX A;  2W5T A;  3NKM A;  4GTW A;  2GA3 A;  4MHX A;  3TWZ A;  3NKP A;  5LIA A;  1ALJ A;  4KAV A;  1E2S P;  1KH5 A;  5IJQ A;  2W8S A;  1EW8 A;  5GOV A;  3LXQ A;  2IUC A;  2ZKT A;  4LRA A;  4ZG7 A;  4KJG A;  1ALK A;  4TN0 A;  2W5W A;  4LRF A;  5LQQ A;  3MK2 A;  3WAX A;  2IUC B;  3BDH A;  3M8Y A;  3KD8 A;  5C66 A;  4LQY A;  3UO0 A;  1KH7 A;  3TX0 A;  1SHQ A;  1ELX A;  1ALH A;  4CYR A;  4UPH A;  4ZG9 A;  1E33 P;  1KHJ A;  3NKR A;  4GTY A;  1KH9 A;  5LRN A;  5DLT A;  1K7H A;  3ED4 A;  3T02 A;  1HDH A;  3NKN A;  2RH6 A;  3T01 A;  1E3C P;  5DLW A;  4CXK A;  1Y7A A;  3UNY A;  4KM4 A;  1URA A;  3IDD A;  2X98 A;  3BDF A;  4GTZ A;  3WAY A;  3WAW A;  4B56 A;  3M8W A;  3UN3 A;  1AJD A;  3NVL A;  2XR9 A;  4UOP A;  2QZU A;  3DYC A;  2W5S A;  5HRT A;  5IJS A;  3T00 A;  5DLV A;  1KHK A;  1EW2 A;  1ANJ A;  4UOO A;  3SZY A;  5KXA A;  1ED9 A;  2GSO A;  3SZZ A;  1KHL A;  4NWJ A;  1HQA A;  4QAX A;  5L0E A;  1AJA A;  1N2K A;  1HJK A;  3B5Q A;  4UPK A;  2W5R A;  4LR9 A;  4CXS A;  2VQR A;  1KH4 A;  1ALI A;  4LR7 A;  5TJ3 A;  5L0B A;  3A52 A;  4MIV A;  4UPL A;  4LRC A;  3NKQ A;  2W5V A;  1E1Z P;  3IGZ B;  4LRE A;  4CXU A;  2IFY A;  1ZEB A;  1URB A;  5GRR A;  3WAV A;  2ANH A;  3IGY B;  1N2L A;  3NKO A;  4FDI A;  5AJ9 A;  3MK0 A;  4LR8 A;  1EI6 A;  1ED8 A;  1P49 A;  1Y6V A;  3WBH A;  4LRD A;  3OT9 A;  2GLQ A;  1AUK A;  5INH A;  5L0K A;  4ZG6 A;  3TG0 A;  3MK1 A;  5K4P A;  4N7T A;  2W5X A;  2G9Y A;  1AJB A;  4FDJ A;  2W5Q A;  4GTX A;  1ELZ A;  5LRM A;  3UN5 A;  1AJC A;  2W8D A;  5EGH A;  4CYS A;  3CMR A;  2GSN A;  1ELY A;  1SHN A;  4MY4 A;  1ANI A;  1EJJ A;  5EGE A;  3BDG A;  3DPC A;  3E2D A;  1KHN A;  3M8Z A;  2XRG A;  4KJD A;  2GSU A;  4UPI A;  1O98 A;  1FSU A;  1O99 A;  4YR1 A;  3BDG B;  2D1G A;  4UOR A;  1B8J A;  1EQJ A;  3UN2 A;  1ZED A;  4ZGA A;  1EW9 A;  4KAY A;  3Q3Q A;  3M7V A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4MY4A

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations