5LRMA

Structure of di-zinc mcr-1 in p41212 space group
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
Knots found
sequence length
323
structure length
312
Chain Sequence
TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords phosphatidylethanolamine transferase Mcr-1
publication title Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1.
pubmed doi rcsb
source organism Escherichia coli
total genus 126
structure length 312
sequence length 323
other databases KnotProt 2.0: S +31
ec nomenclature ec 2.7.-.-:
pdb deposition date 2016-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5lrmA00
1AJBA 5DLVA 5LRMA 3NKRA 1URBA 5LQQA 1AJCA 3UN2A 5L0KA 3NKOA 1ALJA 4LR8A 1ELXA 4UORA 3M8YA 4CXSA 4LR2A 1E2SP 1K7HA 4NWJA 2D1GA 5L0EA 4KJGA 1KHKA 1ALKA 4LRAA 5IJQA 3UO0A 1KHNA 5LIAA 1ANJA 1ELYA 1E33P 4ZGAA 2GSOA 3WAVA 1EW2A 2IUCA 3TX0A 4LREA 1SHQA 1EJJA 3T02A 1O98A 2ANHA 5DLWA 4N7TA 4CXUA 1ELZA 5LRNA 1AJDA 4GTZA 4TN0A 1N2LA 2IUCB 3UNYA 3T01A 4QAXA 4KAVA 4GTWA 4ZG9A 3M8ZA 4LRCA 4LRBA 3M8WA 4CYRA 3A52A 1ALIA 3ED4A 1URAA 1HDHA 3NVLA 2IFYA 4MY4A 3WBHA 1KHJA 4GTXA 4FDJA 4ZG7A 2QZUA 3OT9A 4ZG6A 2W8DA 1EW8A 1EI6A 3NKQA 4UOOA 5C66A 1FSUA 4LRDA 4UPKA 4CXKA 4UPLA 2W5WA 1KH5A 5KXAA 3SZYA 5TJ3A 2GSUA 4KJDA 3IGYB 1AJAA 3BDGA 3DPCA 3DYCA 4UPIA 1HJKA 2W8SA 1ALHA 1EQJA 1HQAA 3NKMA 2W5VA 3BDFA 1EW9A 4LR9A 3NKNA 1ZEDA 4LRFA 2XR9A 4FDIA 5DLTA 3BDGB 2RH6A 1KH4A 4YR1A 1ANIA 2W5XA 4MIVA 3M7VA 3UN5A 2X98A 2W5QA 2W5RA 1SHNA 1Y6VA 3MK2A 5INHA 1AUKA 1ED9A 3E2DA 3WAXA 4CYSA 5L0BA 3BDHA 3MK1A 3WAYA 4KAYA 3LXQA 2GLQA 3B5QA 1O99A 4MHXA 3MK0A 2W5SA 4NWXA 5AJ9A 4KM4A 5HRTA 2ZKTA 2VQRA 4GTYA 1E1ZP 3UN3A 5GRRA 5IJSA 3NKPA 1P49A 4B56A 1Y7AA 3CMRA 4LQYA 1E3CP 5EGEA 3IDDA 4UOPA 2G9YA 1ED8A 3SZZA 4UPHA 2GA3A 3KD8A 3TG0A 1N2KA 3Q3QA 1ZEFA 5K4PA 3WAWA 1KH9A 2GSNA 2W5TA 3TWZA 1KHLA 1B8JA 3IGZB 5EGHA 2XRGA 1ZEBA 3T00A 4LR7A 5GOVA 1KH7A
chains in the Genus database with same CATH superfamily
1AJBA 5DLVA 5LRMA 3NKRA 1URBA 5LQQA 1AJCA 3UN2A 5L0KA 3NKOA 1ALJA 4LR8A 1ELXA 4UORA 3M8YA 4CXSA 4LR2A 1E2SP 1K7HA 4NWJA 2D1GA 5L0EA 4KJGA 1KHKA 1ALKA 4LRAA 5IJQA 3UO0A 1KHNA 5LIAA 1ANJA 1ELYA 1E33P 4ZGAA 2GSOA 3WAVA 1EW2A 2IUCA 3TX0A 4LREA 1SHQA 1EJJA 3T02A 1O98A 2ANHA 5DLWA 4N7TA 4CXUA 1ELZA 5LRNA 1AJDA 4GTZA 4TN0A 1N2LA 2IUCB 3UNYA 3T01A 4QAXA 4KAVA 4GTWA 4ZG9A 3M8ZA 4LRCA 4LRBA 3M8WA 4CYRA 3A52A 1ALIA 3ED4A 1URAA 1HDHA 3NVLA 2IFYA 4MY4A 3WBHA 1KHJA 4GTXA 4FDJA 4ZG7A 2QZUA 3OT9A 4ZG6A 2W8DA 1EW8A 1EI6A 3NKQA 4UOOA 5C66A 1FSUA 4LRDA 4UPKA 4CXKA 4UPLA 2W5WA 1KH5A 5KXAA 3SZYA 5TJ3A 2GSUA 4KJDA 3IGYB 1AJAA 3BDGA 3DPCA 3DYCA 4UPIA 1HJKA 2W8SA 1ALHA 1EQJA 1HQAA 3NKMA 2W5VA 3BDFA 1EW9A 4LR9A 3NKNA 1ZEDA 4LRFA 2XR9A 4FDIA 5DLTA 3BDGB 2RH6A 1KH4A 4YR1A 1ANIA 2W5XA 4MIVA 3M7VA 3UN5A 2X98A 2W5QA 2W5RA 1SHNA 1Y6VA 3MK2A 5INHA 1AUKA 1ED9A 3E2DA 3WAXA 4CYSA 5L0BA 3BDHA 3MK1A 3WAYA 4KAYA 3LXQA 2GLQA 3B5QA 1O99A 4MHXA 3MK0A 2W5SA 4NWXA 5AJ9A 4KM4A 5HRTA 2ZKTA 2VQRA 4GTYA 1E1ZP 3UN3A 5GRRA 5IJSA 3NKPA 1P49A 4B56A 1Y7AA 3CMRA 4LQYA 1E3CP 5EGEA 3IDDA 4UOPA 2G9YA 1ED8A 3SZZA 4UPHA 2GA3A 3KD8A 3TG0A 1N2KA 3Q3QA 1ZEFA 5K4PA 3WAWA 1KH9A 2GSNA 2W5TA 3TWZA 1KHLA 1B8JA 3IGZB 5EGHA 2XRGA 1ZEBA 3T00A 4LR7A 5GOVA 1KH7A
chains in the Genus database with same CATH topology
1AJBA 5DLVA 5LRMA 3NKRA 1URBA 5LQQA 1AJCA 3UN2A 5L0KA 3NKOA 1ALJA 4LR8A 1ELXA 4UORA 3M8YA 4CXSA 4LR2A 1E2SP 1K7HA 4NWJA 2D1GA 5L0EA 4KJGA 1KHKA 1ALKA 4LRAA 5IJQA 3UO0A 1KHNA 5LIAA 1ANJA 1ELYA 1E33P 4ZGAA 2GSOA 3WAVA 1EW2A 2IUCA 3TX0A 4LREA 1SHQA 1EJJA 3T02A 1O98A 2ANHA 5DLWA 4N7TA 4CXUA 1ELZA 5LRNA 1AJDA 4GTZA 4TN0A 1N2LA 2IUCB 3UNYA 3T01A 4QAXA 4KAVA 4GTWA 4ZG9A 3M8ZA 4LRCA 4LRBA 3M8WA 4CYRA 3A52A 1ALIA 3ED4A 1URAA 1HDHA 3NVLA 2IFYA 4MY4A 3WBHA 1KHJA 4GTXA 4FDJA 4ZG7A 2QZUA 3OT9A 4ZG6A 2W8DA 1EW8A 1EI6A 3NKQA 4UOOA 5C66A 1FSUA 4LRDA 4UPKA 4CXKA 4UPLA 2W5WA 1KH5A 5KXAA 3SZYA 5TJ3A 2GSUA 4KJDA 3IGYB 1AJAA 3BDGA 3DPCA 3DYCA 4UPIA 1HJKA 2W8SA 1ALHA 1EQJA 1HQAA 3NKMA 2W5VA 3BDFA 1EW9A 4LR9A 3NKNA 1ZEDA 4LRFA 2XR9A 4FDIA 5DLTA 3BDGB 2RH6A 1KH4A 4YR1A 1ANIA 2W5XA 4MIVA 3M7VA 3UN5A 2X98A 2W5QA 2W5RA 1SHNA 1Y6VA 3MK2A 5INHA 1AUKA 1ED9A 3E2DA 3WAXA 4CYSA 5L0BA 3BDHA 3MK1A 3WAYA 4KAYA 3LXQA 2GLQA 3B5QA 1O99A 4MHXA 3MK0A 2W5SA 4NWXA 5AJ9A 4KM4A 5HRTA 2ZKTA 2VQRA 4GTYA 1E1ZP 3UN3A 5GRRA 5IJSA 3NKPA 1P49A 4B56A 1Y7AA 3CMRA 4LQYA 1E3CP 5EGEA 3IDDA 4UOPA 2G9YA 1ED8A 3SZZA 4UPHA 2GA3A 3KD8A 3TG0A 1N2KA 3Q3QA 1ZEFA 5K4PA 3WAWA 1KH9A 2GSNA 2W5TA 3TWZA 1KHLA 1B8JA 3IGZB 5EGHA 2XRGA 1ZEBA 3T00A 4LR7A 5GOVA 1KH7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AJB A;  5DLV A;  5LRM A;  3NKR A;  1URB A;  5LQQ A;  1AJC A;  3UN2 A;  5L0K A;  3NKO A;  1ALJ A;  4LR8 A;  1ELX A;  4UOR A;  3M8Y A;  4CXS A;  4LR2 A;  1E2S P;  1K7H A;  4NWJ A;  2D1G A;  5L0E A;  4KJG A;  1KHK A;  1ALK A;  4LRA A;  5IJQ A;  3UO0 A;  1KHN A;  5LIA A;  1ANJ A;  1ELY A;  1E33 P;  4ZGA A;  2GSO A;  3WAV A;  1EW2 A;  2IUC A;  3TX0 A;  4LRE A;  1SHQ A;  1EJJ A;  3T02 A;  1O98 A;  2ANH A;  5DLW A;  4N7T A;  4CXU A;  1ELZ A;  5LRN A;  1AJD A;  4GTZ A;  4TN0 A;  1N2L A;  2IUC B;  3UNY A;  3T01 A;  4QAX A;  4KAV A;  4GTW A;  4ZG9 A;  3M8Z A;  4LRC A;  4LRB A;  3M8W A;  4CYR A;  3A52 A;  1ALI A;  3ED4 A;  1URA A;  1HDH A;  3NVL A;  2IFY A;  4MY4 A;  3WBH A;  1KHJ A;  4GTX A;  4FDJ A;  4ZG7 A;  2QZU A;  3OT9 A;  4ZG6 A;  2W8D A;  1EW8 A;  1EI6 A;  3NKQ A;  4UOO A;  5C66 A;  1FSU A;  4LRD A;  4UPK A;  4CXK A;  4UPL A;  2W5W A;  1KH5 A;  5KXA A;  3SZY A;  5TJ3 A;  2GSU A;  4KJD A;  3IGY B;  1AJA A;  3BDG A;  3DPC A;  3DYC A;  4UPI A;  1HJK A;  2W8S A;  1ALH A;  1EQJ A;  1HQA A;  3NKM A;  2W5V A;  3BDF A;  1EW9 A;  4LR9 A;  3NKN A;  1ZED A;  4LRF A;  2XR9 A;  4FDI A;  5DLT A;  3BDG B;  2RH6 A;  1KH4 A;  4YR1 A;  1ANI A;  2W5X A;  4MIV A;  3M7V A;  3UN5 A;  2X98 A;  2W5Q A;  2W5R A;  1SHN A;  1Y6V A;  3MK2 A;  5INH A;  1AUK A;  1ED9 A;  3E2D A;  3WAX A;  4CYS A;  5L0B A;  3BDH A;  3MK1 A;  3WAY A;  4KAY A;  3LXQ A;  2GLQ A;  3B5Q A;  1O99 A;  4MHX A;  3MK0 A;  2W5S A;  4NWX A;  5AJ9 A;  4KM4 A;  5HRT A;  2ZKT A;  2VQR A;  4GTY A;  1E1Z P;  3UN3 A;  5GRR A;  5IJS A;  3NKP A;  1P49 A;  4B56 A;  1Y7A A;  3CMR A;  4LQY A;  1E3C P;  5EGE A;  3IDD A;  4UOP A;  2G9Y A;  1ED8 A;  3SZZ A;  4UPH A;  2GA3 A;  3KD8 A;  3TG0 A;  1N2K A;  3Q3Q A;  1ZEF A;  5K4P A;  3WAW A;  1KH9 A;  2GSN A;  2W5T A;  3TWZ A;  1KHL A;  1B8J A;  3IGZ B;  5EGH A;  2XRG A;  1ZEB A;  3T00 A;  4LR7 A;  5GOV A;  1KH7 A; 
#chains in the Genus database with same CATH topology
 1AJB A;  5DLV A;  5LRM A;  3NKR A;  1URB A;  5LQQ A;  1AJC A;  3UN2 A;  5L0K A;  3NKO A;  1ALJ A;  4LR8 A;  1ELX A;  4UOR A;  3M8Y A;  4CXS A;  4LR2 A;  1E2S P;  1K7H A;  4NWJ A;  2D1G A;  5L0E A;  4KJG A;  1KHK A;  1ALK A;  4LRA A;  5IJQ A;  3UO0 A;  1KHN A;  5LIA A;  1ANJ A;  1ELY A;  1E33 P;  4ZGA A;  2GSO A;  3WAV A;  1EW2 A;  2IUC A;  3TX0 A;  4LRE A;  1SHQ A;  1EJJ A;  3T02 A;  1O98 A;  2ANH A;  5DLW A;  4N7T A;  4CXU A;  1ELZ A;  5LRN A;  1AJD A;  4GTZ A;  4TN0 A;  1N2L A;  2IUC B;  3UNY A;  3T01 A;  4QAX A;  4KAV A;  4GTW A;  4ZG9 A;  3M8Z A;  4LRC A;  4LRB A;  3M8W A;  4CYR A;  3A52 A;  1ALI A;  3ED4 A;  1URA A;  1HDH A;  3NVL A;  2IFY A;  4MY4 A;  3WBH A;  1KHJ A;  4GTX A;  4FDJ A;  4ZG7 A;  2QZU A;  3OT9 A;  4ZG6 A;  2W8D A;  1EW8 A;  1EI6 A;  3NKQ A;  4UOO A;  5C66 A;  1FSU A;  4LRD A;  4UPK A;  4CXK A;  4UPL A;  2W5W A;  1KH5 A;  5KXA A;  3SZY A;  5TJ3 A;  2GSU A;  4KJD A;  3IGY B;  1AJA A;  3BDG A;  3DPC A;  3DYC A;  4UPI A;  1HJK A;  2W8S A;  1ALH A;  1EQJ A;  1HQA A;  3NKM A;  2W5V A;  3BDF A;  1EW9 A;  4LR9 A;  3NKN A;  1ZED A;  4LRF A;  2XR9 A;  4FDI A;  5DLT A;  3BDG B;  2RH6 A;  1KH4 A;  4YR1 A;  1ANI A;  2W5X A;  4MIV A;  3M7V A;  3UN5 A;  2X98 A;  2W5Q A;  2W5R A;  1SHN A;  1Y6V A;  3MK2 A;  5INH A;  1AUK A;  1ED9 A;  3E2D A;  3WAX A;  4CYS A;  5L0B A;  3BDH A;  3MK1 A;  3WAY A;  4KAY A;  3LXQ A;  2GLQ A;  3B5Q A;  1O99 A;  4MHX A;  3MK0 A;  2W5S A;  4NWX A;  5AJ9 A;  4KM4 A;  5HRT A;  2ZKT A;  2VQR A;  4GTY A;  1E1Z P;  3UN3 A;  5GRR A;  5IJS A;  3NKP A;  1P49 A;  4B56 A;  1Y7A A;  3CMR A;  4LQY A;  1E3C P;  5EGE A;  3IDD A;  4UOP A;  2G9Y A;  1ED8 A;  3SZZ A;  4UPH A;  2GA3 A;  3KD8 A;  3TG0 A;  1N2K A;  3Q3Q A;  1ZEF A;  5K4P A;  3WAW A;  1KH9 A;  2GSN A;  2W5T A;  3TWZ A;  1KHL A;  1B8J A;  3IGZ B;  5EGH A;  2XRG A;  1ZEB A;  3T00 A;  4LR7 A;  5GOV A;  1KH7 A; 
#chains in the Genus database with same CATH homology
 1AJB A;  5DLV A;  5LRM A;  3NKR A;  1URB A;  5LQQ A;  1AJC A;  3UN2 A;  5L0K A;  3NKO A;  1ALJ A;  4LR8 A;  1ELX A;  4UOR A;  3M8Y A;  4CXS A;  4LR2 A;  1E2S P;  1K7H A;  4NWJ A;  2D1G A;  5L0E A;  4KJG A;  1KHK A;  1ALK A;  4LRA A;  5IJQ A;  3UO0 A;  1KHN A;  5LIA A;  1ANJ A;  1ELY A;  1E33 P;  4ZGA A;  2GSO A;  3WAV A;  1EW2 A;  2IUC A;  3TX0 A;  4LRE A;  1SHQ A;  1EJJ A;  3T02 A;  1O98 A;  2ANH A;  5DLW A;  4N7T A;  4CXU A;  1ELZ A;  5LRN A;  1AJD A;  4GTZ A;  4TN0 A;  1N2L A;  2IUC B;  3UNY A;  3T01 A;  4QAX A;  4KAV A;  4GTW A;  4ZG9 A;  3M8Z A;  4LRC A;  4LRB A;  3M8W A;  4CYR A;  3A52 A;  1ALI A;  3ED4 A;  1URA A;  1HDH A;  3NVL A;  2IFY A;  4MY4 A;  3WBH A;  1KHJ A;  4GTX A;  4FDJ A;  4ZG7 A;  2QZU A;  3OT9 A;  4ZG6 A;  2W8D A;  1EW8 A;  1EI6 A;  3NKQ A;  4UOO A;  5C66 A;  1FSU A;  4LRD A;  4UPK A;  4CXK A;  4UPL A;  2W5W A;  1KH5 A;  5KXA A;  3SZY A;  5TJ3 A;  2GSU A;  4KJD A;  3IGY B;  1AJA A;  3BDG A;  3DPC A;  3DYC A;  4UPI A;  1HJK A;  2W8S A;  1ALH A;  1EQJ A;  1HQA A;  3NKM A;  2W5V A;  3BDF A;  1EW9 A;  4LR9 A;  3NKN A;  1ZED A;  4LRF A;  2XR9 A;  4FDI A;  5DLT A;  3BDG B;  2RH6 A;  1KH4 A;  4YR1 A;  1ANI A;  2W5X A;  4MIV A;  3M7V A;  3UN5 A;  2X98 A;  2W5Q A;  2W5R A;  1SHN A;  1Y6V A;  3MK2 A;  5INH A;  1AUK A;  1ED9 A;  3E2D A;  3WAX A;  4CYS A;  5L0B A;  3BDH A;  3MK1 A;  3WAY A;  4KAY A;  3LXQ A;  2GLQ A;  3B5Q A;  1O99 A;  4MHX A;  3MK0 A;  2W5S A;  4NWX A;  5AJ9 A;  4KM4 A;  5HRT A;  2ZKT A;  2VQR A;  4GTY A;  1E1Z P;  3UN3 A;  5GRR A;  5IJS A;  3NKP A;  1P49 A;  4B56 A;  1Y7A A;  3CMR A;  4LQY A;  1E3C P;  5EGE A;  3IDD A;  4UOP A;  2G9Y A;  1ED8 A;  3SZZ A;  4UPH A;  2GA3 A;  3KD8 A;  3TG0 A;  1N2K A;  3Q3Q A;  1ZEF A;  5K4P A;  3WAW A;  1KH9 A;  2GSN A;  2W5T A;  3TWZ A;  1KHL A;  1B8J A;  3IGZ B;  5EGH A;  2XRG A;  1ZEB A;  3T00 A;  4LR7 A;  5GOV A;  1KH7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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