3ICUA

Protease-associated domain of the e3 ligase grail
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
171
structure length
171
Chain Sequence
GAMDGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title PA Domain of the E3 Ligase Grail
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase RNF128
total genus 42
structure length 171
sequence length 171
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02225 PA PA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 3icuA01
3SJFA 4OMEA 1Y9ZA 4OC2A 5D29A 4C9RA 3FECA 2JBKA 4C8TA 5F09A 4NGQA 3KASA 4C8PA 2XEJA 2PVWA 2XEFA 4MCPA 3D7GA 4MCRA 4P45A 3FF3A 3SJEA 4CDJA 4NGTA 3S9NA 4P4JA 4NGSA 3S9MA 3VTAA 1XF1A 4C8UA 3D7FA 5ELYA 4TWEA 3D7DA 3I74A 1DE4C 3IWWA 4LQGA 3FEEA 3SJGA 4C99A 3BXMA 4C8CA 2EK8A 4OC3A 3EIFA 4JZ0A 4P4IA 2PVVA 4OC0A 4P4BA 4C86A 2JBJA 4YN3A 4C9EA 4C8FA 4X3RA 4P4DA 3BI1A 4P4EA 2C6CA 2OOTA 2CIJA 4NGNA 1CX8A 3D7HA 4NGRA 4C9UA 4NGPA 4P44A 1Z8LA 4NGMA 4MCSA 3RBUA 4C84A 3S9LA 3SJXA 2XEGA 4TJVA 3FEDA 4KNGE 4JYWA 4OC4A 4CDKA 4C85A 4TJXA 3BI0A 3ICUA 4W9YA 1WVMA 2C6GA 3I6SA 4OC5A 4C9VA 4MCQA 5IB9A 3BHXA 4C8AA 4OC1A 2OR4A 4C9AA 2C6PA 1V6CA 4P4FA 3IIBA 2XEIA 2EK9A
chains in the Genus database with same CATH superfamily
3SJFA 2YJVA 4OMEA 3T05A 1Y9ZA 3EZBA 4OC2A 4IIXA 5D29A 4C9RA 3FECA 2HROA 2JBKA 4C8TA 4E5SA 1DIKA 5F09A 2AUMA 3G23A 4NGQA 5F5XA 1ZRSA 3KASA 1GGOA 4C8PA 2XEJA 2PVWA 2XEFA 4J0NA 2YJTA 3D7GA 4MCPA 4MCRA 1CE8B 3T0TA 3TLBA 1CS0B 2PCNA 3TYXA 4P45A 3FF3A 1KBLA 3TLYA 5FD8A 2HI6A 3SJEA 3TLGA 4NGTA 1VBHA 1ZL0A 4CDJA 4P4JA 3S9NA 4NGSA 1J3LA 2D0PA 1XF1A 3S9MA 3VTAA 4C8UA 4CZ1A 3D7FA 5ELYA 4TWEA 4CO9A 3D7DA 4MI1A 5F1YA 3I74A 1DE4C 3IWWA 4LQGA 3TLZA 2OLSA 3FEEA 3SJGA 4C99A 5F9MA 3K4IA 1NXJA 1EZBA 3BXMA 4EYSA 4C8CA 2EK8A 4OC3A 1C30B 3EIFA 4JZ0A 4P4IA 2PVVA 3T5MA 2C5QA 3KRVA 4OC0A 2D0OA 2MP0A 4P4BA 1Q5XA 4C86A 2JBJA 4YN3A 3TLEA 4C9EA 4C8FA 4JVOA 3U1BA 4X3RA 4COGA 4P4DA 3BI1A 3TLGB 4P4EA 2C6CA 4COBA 2EZAA 1VI4A 2OOTA 3T07A 2CIJA 4NGNA 4E94A 1CX8A 3D7HA 4NGRA 4C9UA 4NGPA 4P44A 3EZAA 1Z8LA 4NGMA 2EZBA 1BXRB 1KEEB 4MCSA 1M6VB 3SR3A 1JDBC 3GJZA 3RBUA 4C84A 3S9LA 1ZYMA 2XEGA 4TJVA 3SJXA 2B0AA 1A9XB 4MJXA 3FEDA 2GP4A 4KNGE 4JYWA 1C3OB 3TLAA 3TLCA 4OC4A 4CDKA 2HWGA 1NBWA 1T36B 4C85A 3EZEA 2EZCA 4INJA 4TJXA 4IIYA 3BI0A 3K9TA 2E28A 3ICUA 4M8DA 4W9YA 1WVMA 2C6GA 3I6SA 4OC5A 1JDEA 4C9VA 1R61A 4MCQA 2DIKA 4H1HA 5IB9A 2R82A 1EZAA 5JVLA 1KC7A 3BHXA 4C8AA 4OC1A 2OR4A 4C9AA 2C6PA 2AUNA 2X0SA 5JYBA 1V6CA 2FM4A 3IIBA 4P4FA 1VBGA 5K99A 2XEIA 5IR2A 3C8OA 2EK9A 3NOJA
chains in the Genus database with same CATH topology
3SJFA 4OMEA 1Y9ZA 4OC2A 5D29A 4C9RA 3FECA 2JBKA 4C8TA 5F09A 4NGQA 3KASA 4C8PA 2XEJA 2PVWA 2XEFA 4MCPA 3D7GA 4MCRA 4P45A 3FF3A 3SJEA 4CDJA 4NGTA 3S9NA 4P4JA 4NGSA 3S9MA 3VTAA 1XF1A 4C8UA 3D7FA 5ELYA 4TWEA 3D7DA 3I74A 1DE4C 3IWWA 4LQGA 3FEEA 3SJGA 4C99A 3BXMA 4C8CA 2EK8A 4OC3A 3EIFA 4JZ0A 4P4IA 2PVVA 2C5QA 4OC0A 4P4BA 4C86A 2JBJA 4YN3A 4C9EA 4C8FA 4X3RA 4P4DA 3BI1A 4P4EA 2C6CA 2OOTA 2CIJA 4NGNA 1CX8A 3D7HA 4NGRA 4C9UA 4NGPA 4P44A 1Z8LA 4NGMA 4MCSA 3RBUA 4C84A 3S9LA 3SJXA 2XEGA 4TJVA 3FEDA 2GP4A 4KNGE 4JYWA 4OC4A 4CDKA 4C85A 4TJXA 3BI0A 3K9TA 3ICUA 4W9YA 1WVMA 2C6GA 3I6SA 4OC5A 4C9VA 4MCQA 5IB9A 3BHXA 4C8AA 4OC1A 2OR4A 4C9AA 2C6PA 1V6CA 4P4FA 3IIBA 2XEIA 5IR2A 2EK9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SJF A;  4OME A;  1Y9Z A;  4OC2 A;  5D29 A;  4C9R A;  3FEC A;  2JBK A;  4C8T A;  5F09 A;  4NGQ A;  3KAS A;  4C8P A;  2XEJ A;  2PVW A;  2XEF A;  4MCP A;  3D7G A;  4MCR A;  4P45 A;  3FF3 A;  3SJE A;  4CDJ A;  4NGT A;  3S9N A;  4P4J A;  4NGS A;  3S9M A;  3VTA A;  1XF1 A;  4C8U A;  3D7F A;  5ELY A;  4TWE A;  3D7D A;  3I74 A;  1DE4 C;  3IWW A;  4LQG A;  3FEE A;  3SJG A;  4C99 A;  3BXM A;  4C8C A;  2EK8 A;  4OC3 A;  3EIF A;  4JZ0 A;  4P4I A;  2PVV A;  4OC0 A;  4P4B A;  4C86 A;  2JBJ A;  4YN3 A;  4C9E A;  4C8F A;  4X3R A;  4P4D A;  3BI1 A;  4P4E A;  2C6C A;  2OOT A;  2CIJ A;  4NGN A;  1CX8 A;  3D7H A;  4NGR A;  4C9U A;  4NGP A;  4P44 A;  1Z8L A;  4NGM A;  4MCS A;  3RBU A;  4C84 A;  3S9L A;  3SJX A;  2XEG A;  4TJV A;  3FED A;  4KNG E;  4JYW A;  4OC4 A;  4CDK A;  4C85 A;  4TJX A;  3BI0 A;  3ICU A;  4W9Y A;  1WVM A;  2C6G A;  3I6S A;  4OC5 A;  4C9V A;  4MCQ A;  5IB9 A;  3BHX A;  4C8A A;  4OC1 A;  2OR4 A;  4C9A A;  2C6P A;  1V6C A;  4P4F A;  3IIB A;  2XEI A;  2EK9 A; 
#chains in the Genus database with same CATH topology
 3SJF A;  2YJV A;  4OME A;  3T05 A;  1Y9Z A;  3EZB A;  4OC2 A;  4IIX A;  5D29 A;  4C9R A;  3FEC A;  2HRO A;  2JBK A;  4C8T A;  4E5S A;  1DIK A;  5F09 A;  2AUM A;  3G23 A;  4NGQ A;  5F5X A;  1ZRS A;  3KAS A;  1GGO A;  4C8P A;  2XEJ A;  2PVW A;  2XEF A;  4J0N A;  2YJT A;  3D7G A;  4MCP A;  4MCR A;  1CE8 B;  3T0T A;  3TLB A;  1CS0 B;  2PCN A;  3TYX A;  4P45 A;  3FF3 A;  1KBL A;  3TLY A;  5FD8 A;  2HI6 A;  3SJE A;  3TLG A;  4NGT A;  1VBH A;  1ZL0 A;  4CDJ A;  4P4J A;  3S9N A;  4NGS A;  1J3L A;  2D0P A;  1XF1 A;  3S9M A;  3VTA A;  4C8U A;  4CZ1 A;  3D7F A;  5ELY A;  4TWE A;  4CO9 A;  3D7D A;  4MI1 A;  5F1Y A;  3I74 A;  1DE4 C;  3IWW A;  4LQG A;  3TLZ A;  2OLS A;  3FEE A;  3SJG A;  4C99 A;  5F9M A;  3K4I A;  1NXJ A;  1EZB A;  3BXM A;  4EYS A;  4C8C A;  2EK8 A;  4OC3 A;  1C30 B;  3EIF A;  4JZ0 A;  4P4I A;  2PVV A;  3T5M A;  2C5Q A;  3KRV A;  4OC0 A;  2D0O A;  2MP0 A;  4P4B A;  1Q5X A;  4C86 A;  2JBJ A;  4YN3 A;  3TLE A;  4C9E A;  4C8F A;  4JVO A;  3U1B A;  4X3R A;  4COG A;  4P4D A;  3BI1 A;  3TLG B;  4P4E A;  2C6C A;  4COB A;  2EZA A;  1VI4 A;  2OOT A;  3T07 A;  2CIJ A;  4NGN A;  4E94 A;  1CX8 A;  3D7H A;  4NGR A;  4C9U A;  4NGP A;  4P44 A;  3EZA A;  1Z8L A;  4NGM A;  2EZB A;  1BXR B;  1KEE B;  4MCS A;  1M6V B;  3SR3 A;  1JDB C;  3GJZ A;  3RBU A;  4C84 A;  3S9L A;  1ZYM A;  2XEG A;  4TJV A;  3SJX A;  2B0A A;  1A9X B;  4MJX A;  3FED A;  2GP4 A;  4KNG E;  4JYW A;  1C3O B;  3TLA A;  3TLC A;  4OC4 A;  4CDK A;  2HWG A;  1NBW A;  1T36 B;  4C85 A;  3EZE A;  2EZC A;  4INJ A;  4TJX A;  4IIY A;  3BI0 A;  3K9T A;  2E28 A;  3ICU A;  4M8D A;  4W9Y A;  1WVM A;  2C6G A;  3I6S A;  4OC5 A;  1JDE A;  4C9V A;  1R61 A;  4MCQ A;  2DIK A;  4H1H A;  5IB9 A;  2R82 A;  1EZA A;  5JVL A;  1KC7 A;  3BHX A;  4C8A A;  4OC1 A;  2OR4 A;  4C9A A;  2C6P A;  2AUN A;  2X0S A;  5JYB A;  1V6C A;  2FM4 A;  3IIB A;  4P4F A;  1VBG A;  5K99 A;  2XEI A;  5IR2 A;  3C8O A;  2EK9 A;  3NOJ A; 
#chains in the Genus database with same CATH homology
 3SJF A;  4OME A;  1Y9Z A;  4OC2 A;  5D29 A;  4C9R A;  3FEC A;  2JBK A;  4C8T A;  5F09 A;  4NGQ A;  3KAS A;  4C8P A;  2XEJ A;  2PVW A;  2XEF A;  4MCP A;  3D7G A;  4MCR A;  4P45 A;  3FF3 A;  3SJE A;  4CDJ A;  4NGT A;  3S9N A;  4P4J A;  4NGS A;  3S9M A;  3VTA A;  1XF1 A;  4C8U A;  3D7F A;  5ELY A;  4TWE A;  3D7D A;  3I74 A;  1DE4 C;  3IWW A;  4LQG A;  3FEE A;  3SJG A;  4C99 A;  3BXM A;  4C8C A;  2EK8 A;  4OC3 A;  3EIF A;  4JZ0 A;  4P4I A;  2PVV A;  2C5Q A;  4OC0 A;  4P4B A;  4C86 A;  2JBJ A;  4YN3 A;  4C9E A;  4C8F A;  4X3R A;  4P4D A;  3BI1 A;  4P4E A;  2C6C A;  2OOT A;  2CIJ A;  4NGN A;  1CX8 A;  3D7H A;  4NGR A;  4C9U A;  4NGP A;  4P44 A;  1Z8L A;  4NGM A;  4MCS A;  3RBU A;  4C84 A;  3S9L A;  3SJX A;  2XEG A;  4TJV A;  3FED A;  2GP4 A;  4KNG E;  4JYW A;  4OC4 A;  4CDK A;  4C85 A;  4TJX A;  3BI0 A;  3K9T A;  3ICU A;  4W9Y A;  1WVM A;  2C6G A;  3I6S A;  4OC5 A;  4C9V A;  4MCQ A;  5IB9 A;  3BHX A;  4C8A A;  4OC1 A;  2OR4 A;  4C9A A;  2C6P A;  1V6C A;  4P4F A;  3IIB A;  2XEI A;  5IR2 A;  2EK9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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