3ICUA

Protease-associated domain of the e3 ligase grail
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
171
structure length
171
Chain Sequence
GAMDGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
source organism Homo sapiens
publication title PA Domain of the E3 Ligase Grail
rcsb
molecule keywords E3 ubiquitin-protein ligase RNF128
total genus 42
structure length 171
sequence length 171
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02225 PA PA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 3icuA01
4TWEA 4MCPA 4P45A 5D29A 3D7GA 4OC2A 4CDKA 4OC3A 3IIBA 4W9YA 4CDJA 4X3RA 1Z8LA 3SJXA 2XEJA 4P4JA 3BI0A 4C9RA 3D7FA 1CX8A 1DE4C 2JBKA 2EK9A 3IWWA 4P4FA 4MCSA 4P4EA 1V6CA 3FF3A 2JBJA 4C9AA 4NGTA 3SJFA 1Y9ZA 2PVVA 2EK8A 5F09A 4P4BA 2C6CA 4C99A 5IB9A 3S9LA 4C9VA 4NGQA 4TJXA 3FEEA 2XEIA 2C6GA 3BXMA 2XEGA 4OC0A 4NGNA 4NGRA 4C8AA 2PVWA 4P4DA 2XEFA 3FEDA 2OOTA 4KNGE 4OC1A 3SJEA 1XF1A 4NGSA 4C8FA 3BI1A 3S9NA 4NGPA 4YN3A 2CIJA 1WVMA 4C9EA 3D7HA 3KASA 4P4IA 4C8PA 4MCRA 4OC5A 3EIFA 3BHXA 3I74A 4OC4A 4JZ0A 4NGMA 4MCQA 3VTAA 4C9UA 4P44A 4C85A 3D7DA 3S9MA 2OR4A 4LQGA 3RBUA 4JYWA 4OMEA 5ELYA 4C86A 2C6PA 3I6SA 4C8CA 3SJGA 3ICUA 4TJVA 4C8TA 3FECA 4C8UA 4C84A
chains in the Genus database with same CATH superfamily
2OLSA 5FD8A 1ZRSA 4TWEA 4MCPA 3TLAA 4P45A 2B0AA 3U1BA 5D29A 2YJVA 3D7GA 4OC2A 4CDKA 1KC7A 4OC3A 1EZBA 3IIBA 4E5SA 4W9YA 4CDJA 4X3RA 1VBHA 1Z8LA 3TLCA 3GJZA 1NBWA 2YJTA 3SJXA 2XEJA 4J0NA 4P4JA 3BI0A 4C9RA 4H1HA 3D7FA 3G23A 1Q5XA 1CX8A 2D0PA 1DE4C 2JBKA 5K99A 2EK9A 3IWWA 4P4FA 4CO9A 4MCSA 2D0OA 4P4EA 1V6CA 1CS0B 3FF3A 2E28A 2HI6A 2JBJA 3T07A 2EZBA 2X0SA 1NXJA 4IIYA 4C9AA 4NGTA 3SJFA 3TLZA 1Y9ZA 3TLGB 2PVVA 2EK8A 5IR2A 5F09A 4P4BA 1VI4A 3KRVA 3TLGA 2C6CA 4C99A 5IB9A 3S9LA 3TLEA 1VBGA 4C9VA 4M8DA 2HROA 4NGQA 4TJXA 3FEEA 2XEIA 2C6GA 3BXMA 4JVOA 4E94A 3EZEA 2XEGA 4OC0A 5F5XA 4NGNA 1GGOA 1KEEB 2DIKA 4NGRA 4C8AA 2PVWA 4P4DA 2XEFA 3FEDA 3SR3A 1C3OB 2OOTA 4KNGE 3TLBA 2AUNA 4OC1A 3SJEA 1XF1A 4NGSA 1BXRB 1R61A 1ZL0A 4C8FA 3BI1A 3S9NA 4NGPA 4YN3A 2GP4A 4MJXA 2MP0A 5JYBA 4COBA 4COGA 1CE8B 2CIJA 1WVMA 2EZCA 2R82A 4C9EA 4CZ1A 3D7HA 3KASA 4P4IA 4C8PA 3T0TA 4MCRA 1C30B 4OC5A 3EIFA 3BHXA 3I74A 4OC4A 4JZ0A 2FM4A 4MCQA 4NGMA 1A9XB 2EZAA 5F1YA 3TYXA 2PCNA 3VTAA 1ZYMA 1DIKA 3EZBA 1T36B 4C9UA 3T05A 1JDEA 4P44A 4C85A 3D7DA 3S9MA 3TLYA 1EZAA 2HWGA 2OR4A 3EZAA 4LQGA 3RBUA 5F9MA 4JYWA 4OMEA 5ELYA 4C86A 1M6VB 2C5QA 2C6PA 3K4IA 3NOJA 3K9TA 3T5MA 5JVLA 3I6SA 4C8CA 1KBLA 4IIXA 2AUMA 4INJA 3SJGA 3ICUA 4EYSA 4TJVA 4MI1A 1J3LA 4C8TA 3FECA 3C8OA 4C8UA 4C84A 1JDBC
chains in the Genus database with same CATH topology
4TWEA 4MCPA 4P45A 5D29A 3D7GA 4OC2A 4CDKA 4OC3A 3IIBA 4W9YA 4CDJA 4X3RA 1Z8LA 3SJXA 2XEJA 4P4JA 3BI0A 4C9RA 3D7FA 1CX8A 1DE4C 2JBKA 2EK9A 3IWWA 4P4FA 4MCSA 4P4EA 1V6CA 3FF3A 2JBJA 4C9AA 4NGTA 3SJFA 1Y9ZA 2PVVA 2EK8A 5IR2A 5F09A 4P4BA 2C6CA 4C99A 5IB9A 3S9LA 4C9VA 4NGQA 4TJXA 3FEEA 2XEIA 2C6GA 3BXMA 2XEGA 4OC0A 4NGNA 4NGRA 4C8AA 2PVWA 4P4DA 2XEFA 3FEDA 2OOTA 4KNGE 4OC1A 3SJEA 1XF1A 4NGSA 4C8FA 3BI1A 3S9NA 4NGPA 4YN3A 2GP4A 2CIJA 1WVMA 4C9EA 3D7HA 3KASA 4P4IA 4C8PA 4MCRA 4OC5A 3EIFA 3BHXA 3I74A 4OC4A 4JZ0A 4NGMA 4MCQA 3VTAA 4C9UA 4P44A 4C85A 3D7DA 3S9MA 2OR4A 4LQGA 3RBUA 4JYWA 4OMEA 5ELYA 4C86A 2C5QA 2C6PA 3K9TA 3I6SA 4C8CA 3SJGA 3ICUA 4TJVA 4C8TA 3FECA 4C8UA 4C84A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TWE A;  4MCP A;  4P45 A;  5D29 A;  3D7G A;  4OC2 A;  4CDK A;  4OC3 A;  3IIB A;  4W9Y A;  4CDJ A;  4X3R A;  1Z8L A;  3SJX A;  2XEJ A;  4P4J A;  3BI0 A;  4C9R A;  3D7F A;  1CX8 A;  1DE4 C;  2JBK A;  2EK9 A;  3IWW A;  4P4F A;  4MCS A;  4P4E A;  1V6C A;  3FF3 A;  2JBJ A;  4C9A A;  4NGT A;  3SJF A;  1Y9Z A;  2PVV A;  2EK8 A;  5F09 A;  4P4B A;  2C6C A;  4C99 A;  5IB9 A;  3S9L A;  4C9V A;  4NGQ A;  4TJX A;  3FEE A;  2XEI A;  2C6G A;  3BXM A;  2XEG A;  4OC0 A;  4NGN A;  4NGR A;  4C8A A;  2PVW A;  4P4D A;  2XEF A;  3FED A;  2OOT A;  4KNG E;  4OC1 A;  3SJE A;  1XF1 A;  4NGS A;  4C8F A;  3BI1 A;  3S9N A;  4NGP A;  4YN3 A;  2CIJ A;  1WVM A;  4C9E A;  3D7H A;  3KAS A;  4P4I A;  4C8P A;  4MCR A;  4OC5 A;  3EIF A;  3BHX A;  3I74 A;  4OC4 A;  4JZ0 A;  4NGM A;  4MCQ A;  3VTA A;  4C9U A;  4P44 A;  4C85 A;  3D7D A;  3S9M A;  2OR4 A;  4LQG A;  3RBU A;  4JYW A;  4OME A;  5ELY A;  4C86 A;  2C6P A;  3I6S A;  4C8C A;  3SJG A;  3ICU A;  4TJV A;  4C8T A;  3FEC A;  4C8U A;  4C84 A; 
#chains in the Genus database with same CATH topology
 2OLS A;  5FD8 A;  1ZRS A;  4TWE A;  4MCP A;  3TLA A;  4P45 A;  2B0A A;  3U1B A;  5D29 A;  2YJV A;  3D7G A;  4OC2 A;  4CDK A;  1KC7 A;  4OC3 A;  1EZB A;  3IIB A;  4E5S A;  4W9Y A;  4CDJ A;  4X3R A;  1VBH A;  1Z8L A;  3TLC A;  3GJZ A;  1NBW A;  2YJT A;  3SJX A;  2XEJ A;  4J0N A;  4P4J A;  3BI0 A;  4C9R A;  4H1H A;  3D7F A;  3G23 A;  1Q5X A;  1CX8 A;  2D0P A;  1DE4 C;  2JBK A;  5K99 A;  2EK9 A;  3IWW A;  4P4F A;  4CO9 A;  4MCS A;  2D0O A;  4P4E A;  1V6C A;  1CS0 B;  3FF3 A;  2E28 A;  2HI6 A;  2JBJ A;  3T07 A;  2EZB A;  2X0S A;  1NXJ A;  4IIY A;  4C9A A;  4NGT A;  3SJF A;  3TLZ A;  1Y9Z A;  3TLG B;  2PVV A;  2EK8 A;  5IR2 A;  5F09 A;  4P4B A;  1VI4 A;  3KRV A;  3TLG A;  2C6C A;  4C99 A;  5IB9 A;  3S9L A;  3TLE A;  1VBG A;  4C9V A;  4M8D A;  2HRO A;  4NGQ A;  4TJX A;  3FEE A;  2XEI A;  2C6G A;  3BXM A;  4JVO A;  4E94 A;  3EZE A;  2XEG A;  4OC0 A;  5F5X A;  4NGN A;  1GGO A;  1KEE B;  2DIK A;  4NGR A;  4C8A A;  2PVW A;  4P4D A;  2XEF A;  3FED A;  3SR3 A;  1C3O B;  2OOT A;  4KNG E;  3TLB A;  2AUN A;  4OC1 A;  3SJE A;  1XF1 A;  4NGS A;  1BXR B;  1R61 A;  1ZL0 A;  4C8F A;  3BI1 A;  3S9N A;  4NGP A;  4YN3 A;  2GP4 A;  4MJX A;  2MP0 A;  5JYB A;  4COB A;  4COG A;  1CE8 B;  2CIJ A;  1WVM A;  2EZC A;  2R82 A;  4C9E A;  4CZ1 A;  3D7H A;  3KAS A;  4P4I A;  4C8P A;  3T0T A;  4MCR A;  1C30 B;  4OC5 A;  3EIF A;  3BHX A;  3I74 A;  4OC4 A;  4JZ0 A;  2FM4 A;  4MCQ A;  4NGM A;  1A9X B;  2EZA A;  5F1Y A;  3TYX A;  2PCN A;  3VTA A;  1ZYM A;  1DIK A;  3EZB A;  1T36 B;  4C9U A;  3T05 A;  1JDE A;  4P44 A;  4C85 A;  3D7D A;  3S9M A;  3TLY A;  1EZA A;  2HWG A;  2OR4 A;  3EZA A;  4LQG A;  3RBU A;  5F9M A;  4JYW A;  4OME A;  5ELY A;  4C86 A;  1M6V B;  2C5Q A;  2C6P A;  3K4I A;  3NOJ A;  3K9T A;  3T5M A;  5JVL A;  3I6S A;  4C8C A;  1KBL A;  4IIX A;  2AUM A;  4INJ A;  3SJG A;  3ICU A;  4EYS A;  4TJV A;  4MI1 A;  1J3L A;  4C8T A;  3FEC A;  3C8O A;  4C8U A;  4C84 A;  1JDB C; 
#chains in the Genus database with same CATH homology
 4TWE A;  4MCP A;  4P45 A;  5D29 A;  3D7G A;  4OC2 A;  4CDK A;  4OC3 A;  3IIB A;  4W9Y A;  4CDJ A;  4X3R A;  1Z8L A;  3SJX A;  2XEJ A;  4P4J A;  3BI0 A;  4C9R A;  3D7F A;  1CX8 A;  1DE4 C;  2JBK A;  2EK9 A;  3IWW A;  4P4F A;  4MCS A;  4P4E A;  1V6C A;  3FF3 A;  2JBJ A;  4C9A A;  4NGT A;  3SJF A;  1Y9Z A;  2PVV A;  2EK8 A;  5IR2 A;  5F09 A;  4P4B A;  2C6C A;  4C99 A;  5IB9 A;  3S9L A;  4C9V A;  4NGQ A;  4TJX A;  3FEE A;  2XEI A;  2C6G A;  3BXM A;  2XEG A;  4OC0 A;  4NGN A;  4NGR A;  4C8A A;  2PVW A;  4P4D A;  2XEF A;  3FED A;  2OOT A;  4KNG E;  4OC1 A;  3SJE A;  1XF1 A;  4NGS A;  4C8F A;  3BI1 A;  3S9N A;  4NGP A;  4YN3 A;  2GP4 A;  2CIJ A;  1WVM A;  4C9E A;  3D7H A;  3KAS A;  4P4I A;  4C8P A;  4MCR A;  4OC5 A;  3EIF A;  3BHX A;  3I74 A;  4OC4 A;  4JZ0 A;  4NGM A;  4MCQ A;  3VTA A;  4C9U A;  4P44 A;  4C85 A;  3D7D A;  3S9M A;  2OR4 A;  4LQG A;  3RBU A;  4JYW A;  4OME A;  5ELY A;  4C86 A;  2C5Q A;  2C6P A;  3K9T A;  3I6S A;  4C8C A;  3SJG A;  3ICU A;  4TJV A;  4C8T A;  3FEC A;  4C8U A;  4C84 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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