4C85A

Zebrafish znrf3 ectodomain crystal form ii
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
151
structure length
143
Chain Sequence
DTAFVEVVLFESSPNGDYTTYTTGLQGRFSRAGATISAEGEIVQMHPLGDLYEYGWVGVVKLEQPELDPSCLTVLGKAKRAVQRGATAVIFDVSENPDAIDQLNQVSEDPLKRPVVYVKGADAVKLMNIVNKQKVARARIQHR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords E3 UBIQUITIN-PROTEIN LIGASE ZNRF3
publication title Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
pubmed doi rcsb
source organism Danio rerio
molecule tags Ligase
total genus 36
structure length 143
sequence length 151
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18212 ZNRF_3_ecto ZNRF-3 Ectodomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 4c85A00
1Z8LA 2CIJA 5ELYA 4C99A 3EIFA 4P4FA 4P4EA 4C85A 1Y9ZA 3SJXA 4C86A 4C9VA 4TJVA 4MCQA 5D29A 3FEEA 3SJGA 3IWWA 4OC5A 3SJFA 2PVVA 3FEDA 4MCSA 4JZ0A 3FF3A 4CDJA 3BHXA 4P4BA 2XEIA 3S9LA 3D7GA 2OOTA 4P45A 4OC2A 3IIBA 4P4IA 3ICUA 3D7FA 4KNGE 4C8CA 4NGMA 2C6CA 3I6SA 4MCPA 4X3RA 4TWEA 4P44A 3D7DA 1V6CA 5F09A 3I74A 3BI1A 4OC3A 4TJXA 4NGSA 4P4DA 4OC1A 4MCRA 4C8FA 4CDKA 3D7HA 1CX8A 4C8PA 4C9UA 4W9YA 1DE4C 2JBKA 3BXMA 4NGPA 4YN3A 3S9MA 2C6PA 2JBJA 1WVMA 2OR4A 3RBUA 3VTAA 4NGTA 4P4JA 4NGQA 3S9NA 4OC0A 2PVWA 5IB9A 4C9AA 4C8UA 2XEJA 4OMEA 3BI0A 2XEGA 3FECA 4C84A 2C6GA 2XEFA 2EK8A 4JYWA 4C9EA 4OC4A 4C8TA 4C8AA 4NGRA 4LQGA 4C9RA 4NGNA 3SJEA 1XF1A 3KASA 2EK9A
chains in the Genus database with same CATH superfamily
1KEEB 1Z8LA 2CIJA 5ELYA 4C99A 2GP4A 3EIFA 1Q5XA 2EZBA 4P4FA 2D0OA 4J0NA 4P4EA 4C85A 3KASA 1VBHA 1C30B 2B0AA 1Y9ZA 3SJXA 4E94A 4C86A 4C9VA 4TJVA 4MCQA 1ZYMA 1KC7A 5D29A 3FEEA 1GGOA 1BXRB 5FD8A 3K9TA 2C5QA 4JVOA 3SJGA 1VI4A 3IWWA 3TLAA 4OC5A 3T0TA 2EZAA 2FM4A 3SJFA 2PVVA 3FEDA 4MCSA 3TLGB 4JZ0A 1KBLA 3TLYA 2E28A 3FF3A 2DIKA 3G23A 4CDJA 3BHXA 4P4BA 2XEIA 5F1YA 3NOJA 3S9LA 3D7GA 2EZCA 4INJA 2OOTA 1EZBA 3TLGA 3TYXA 4P45A 3T07A 5IR2A 4OC2A 5JYBA 2R82A 3IIBA 4IIYA 4P4IA 3ICUA 4EYSA 3D7FA 4KNGE 1NBWA 4C8CA 3EZEA 3EZAA 1VBGA 3TLZA 2HI6A 1JDEA 3KRVA 4NGMA 1ZL0A 3I6SA 4MI1A 4MCPA 4X3RA 4CO9A 1JDBC 4TWEA 4P44A 1C3OB 1EZAA 3D7DA 2PCNA 1V6CA 1M6VB 2AUNA 3I74A 5F09A 2OLSA 1CS0B 3BI1A 1DIKA 4COBA 4OC3A 4TJXA 4NGSA 3TLCA 4P4DA 2D0PA 4OC1A 4MCRA 4C8FA 4CDKA 3D7HA 1CX8A 4C8PA 3U1BA 5F5XA 1J3LA 1NXJA 1T36B 4C9UA 4W9YA 1DE4C 2JBKA 4E5SA 3BXMA 4NGPA 4COGA 4YN3A 3TLBA 3S9MA 2C6PA 2JBJA 4H1HA 1WVMA 2OR4A 3RBUA 3VTAA 5JVLA 4NGTA 4P4JA 4NGQA 3K4IA 3S9NA 2PVWA 4OC0A 5IB9A 4C9AA 3C8OA 1R61A 4C8UA 3T5MA 2XEJA 4OMEA 3BI0A 2XEGA 2X0SA 3GJZA 3FECA 4IIXA 4C84A 2MP0A 5F9MA 3EZBA 2HROA 3T05A 2HWGA 5K99A 4MJXA 2C6GA 2XEFA 2EK8A 1A9XB 4M8DA 4JYWA 3TLEA 4OC4A 4C9EA 2YJTA 4C8TA 2AUMA 3SR3A 1ZRSA 4C8AA 1CE8B 4NGRA 4LQGA 4C9RA 4NGNA 4CZ1A 3SJEA 1XF1A 2C6CA 2EK9A 2YJVA
chains in the Genus database with same CATH topology
1Z8LA 2CIJA 5ELYA 4C99A 2GP4A 3EIFA 4P4FA 4P4EA 4C85A 1Y9ZA 3SJXA 4C86A 4C9VA 4TJVA 4MCQA 5D29A 3FEEA 3K9TA 2C5QA 3SJGA 3IWWA 4OC5A 3SJFA 2PVVA 3FEDA 4MCSA 4JZ0A 3FF3A 4CDJA 3BHXA 4P4BA 2XEIA 3S9LA 3D7GA 2OOTA 4P45A 5IR2A 4OC2A 3IIBA 4P4IA 3ICUA 3D7FA 4KNGE 4C8CA 4NGMA 2C6CA 3I6SA 4MCPA 4X3RA 4TWEA 4P44A 3D7DA 1V6CA 5F09A 3I74A 3BI1A 4OC3A 4TJXA 4NGSA 4P4DA 4OC1A 4MCRA 4C8FA 4CDKA 3D7HA 1CX8A 4C8PA 4C9UA 4W9YA 1DE4C 2JBKA 3BXMA 4NGPA 4YN3A 3S9MA 2C6PA 2JBJA 1WVMA 2OR4A 3RBUA 3VTAA 4NGTA 4P4JA 4NGQA 3S9NA 2PVWA 4OC0A 5IB9A 4C9AA 4C8UA 2XEJA 4OMEA 3BI0A 2XEGA 3FECA 4C84A 2C6GA 2XEFA 2EK8A 4JYWA 4C9EA 4OC4A 4C8TA 4C8AA 4NGRA 4LQGA 4C9RA 4NGNA 3SJEA 1XF1A 3KASA 2EK9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z8L A;  2CIJ A;  5ELY A;  4C99 A;  3EIF A;  4P4F A;  4P4E A;  4C85 A;  1Y9Z A;  3SJX A;  4C86 A;  4C9V A;  4TJV A;  4MCQ A;  5D29 A;  3FEE A;  3SJG A;  3IWW A;  4OC5 A;  3SJF A;  2PVV A;  3FED A;  4MCS A;  4JZ0 A;  3FF3 A;  4CDJ A;  3BHX A;  4P4B A;  2XEI A;  3S9L A;  3D7G A;  2OOT A;  4P45 A;  4OC2 A;  3IIB A;  4P4I A;  3ICU A;  3D7F A;  4KNG E;  4C8C A;  4NGM A;  2C6C A;  3I6S A;  4MCP A;  4X3R A;  4TWE A;  4P44 A;  3D7D A;  1V6C A;  5F09 A;  3I74 A;  3BI1 A;  4OC3 A;  4TJX A;  4NGS A;  4P4D A;  4OC1 A;  4MCR A;  4C8F A;  4CDK A;  3D7H A;  1CX8 A;  4C8P A;  4C9U A;  4W9Y A;  1DE4 C;  2JBK A;  3BXM A;  4NGP A;  4YN3 A;  3S9M A;  2C6P A;  2JBJ A;  1WVM A;  2OR4 A;  3RBU A;  3VTA A;  4NGT A;  4P4J A;  4NGQ A;  3S9N A;  4OC0 A;  2PVW A;  5IB9 A;  4C9A A;  4C8U A;  2XEJ A;  4OME A;  3BI0 A;  2XEG A;  3FEC A;  4C84 A;  2C6G A;  2XEF A;  2EK8 A;  4JYW A;  4C9E A;  4OC4 A;  4C8T A;  4C8A A;  4NGR A;  4LQG A;  4C9R A;  4NGN A;  3SJE A;  1XF1 A;  3KAS A;  2EK9 A; 
#chains in the Genus database with same CATH topology
 1KEE B;  1Z8L A;  2CIJ A;  5ELY A;  4C99 A;  2GP4 A;  3EIF A;  1Q5X A;  2EZB A;  4P4F A;  2D0O A;  4J0N A;  4P4E A;  4C85 A;  3KAS A;  1VBH A;  1C30 B;  2B0A A;  1Y9Z A;  3SJX A;  4E94 A;  4C86 A;  4C9V A;  4TJV A;  4MCQ A;  1ZYM A;  1KC7 A;  5D29 A;  3FEE A;  1GGO A;  1BXR B;  5FD8 A;  3K9T A;  2C5Q A;  4JVO A;  3SJG A;  1VI4 A;  3IWW A;  3TLA A;  4OC5 A;  3T0T A;  2EZA A;  2FM4 A;  3SJF A;  2PVV A;  3FED A;  4MCS A;  3TLG B;  4JZ0 A;  1KBL A;  3TLY A;  2E28 A;  3FF3 A;  2DIK A;  3G23 A;  4CDJ A;  3BHX A;  4P4B A;  2XEI A;  5F1Y A;  3NOJ A;  3S9L A;  3D7G A;  2EZC A;  4INJ A;  2OOT A;  1EZB A;  3TLG A;  3TYX A;  4P45 A;  3T07 A;  5IR2 A;  4OC2 A;  5JYB A;  2R82 A;  3IIB A;  4IIY A;  4P4I A;  3ICU A;  4EYS A;  3D7F A;  4KNG E;  1NBW A;  4C8C A;  3EZE A;  3EZA A;  1VBG A;  3TLZ A;  2HI6 A;  1JDE A;  3KRV A;  4NGM A;  1ZL0 A;  3I6S A;  4MI1 A;  4MCP A;  4X3R A;  4CO9 A;  1JDB C;  4TWE A;  4P44 A;  1C3O B;  1EZA A;  3D7D A;  2PCN A;  1V6C A;  1M6V B;  2AUN A;  3I74 A;  5F09 A;  2OLS A;  1CS0 B;  3BI1 A;  1DIK A;  4COB A;  4OC3 A;  4TJX A;  4NGS A;  3TLC A;  4P4D A;  2D0P A;  4OC1 A;  4MCR A;  4C8F A;  4CDK A;  3D7H A;  1CX8 A;  4C8P A;  3U1B A;  5F5X A;  1J3L A;  1NXJ A;  1T36 B;  4C9U A;  4W9Y A;  1DE4 C;  2JBK A;  4E5S A;  3BXM A;  4NGP A;  4COG A;  4YN3 A;  3TLB A;  3S9M A;  2C6P A;  2JBJ A;  4H1H A;  1WVM A;  2OR4 A;  3RBU A;  3VTA A;  5JVL A;  4NGT A;  4P4J A;  4NGQ A;  3K4I A;  3S9N A;  2PVW A;  4OC0 A;  5IB9 A;  4C9A A;  3C8O A;  1R61 A;  4C8U A;  3T5M A;  2XEJ A;  4OME A;  3BI0 A;  2XEG A;  2X0S A;  3GJZ A;  3FEC A;  4IIX A;  4C84 A;  2MP0 A;  5F9M A;  3EZB A;  2HRO A;  3T05 A;  2HWG A;  5K99 A;  4MJX A;  2C6G A;  2XEF A;  2EK8 A;  1A9X B;  4M8D A;  4JYW A;  3TLE A;  4OC4 A;  4C9E A;  2YJT A;  4C8T A;  2AUM A;  3SR3 A;  1ZRS A;  4C8A A;  1CE8 B;  4NGR A;  4LQG A;  4C9R A;  4NGN A;  4CZ1 A;  3SJE A;  1XF1 A;  2C6C A;  2EK9 A;  2YJV A; 
#chains in the Genus database with same CATH homology
 1Z8L A;  2CIJ A;  5ELY A;  4C99 A;  2GP4 A;  3EIF A;  4P4F A;  4P4E A;  4C85 A;  1Y9Z A;  3SJX A;  4C86 A;  4C9V A;  4TJV A;  4MCQ A;  5D29 A;  3FEE A;  3K9T A;  2C5Q A;  3SJG A;  3IWW A;  4OC5 A;  3SJF A;  2PVV A;  3FED A;  4MCS A;  4JZ0 A;  3FF3 A;  4CDJ A;  3BHX A;  4P4B A;  2XEI A;  3S9L A;  3D7G A;  2OOT A;  4P45 A;  5IR2 A;  4OC2 A;  3IIB A;  4P4I A;  3ICU A;  3D7F A;  4KNG E;  4C8C A;  4NGM A;  2C6C A;  3I6S A;  4MCP A;  4X3R A;  4TWE A;  4P44 A;  3D7D A;  1V6C A;  5F09 A;  3I74 A;  3BI1 A;  4OC3 A;  4TJX A;  4NGS A;  4P4D A;  4OC1 A;  4MCR A;  4C8F A;  4CDK A;  3D7H A;  1CX8 A;  4C8P A;  4C9U A;  4W9Y A;  1DE4 C;  2JBK A;  3BXM A;  4NGP A;  4YN3 A;  3S9M A;  2C6P A;  2JBJ A;  1WVM A;  2OR4 A;  3RBU A;  3VTA A;  4NGT A;  4P4J A;  4NGQ A;  3S9N A;  2PVW A;  4OC0 A;  5IB9 A;  4C9A A;  4C8U A;  2XEJ A;  4OME A;  3BI0 A;  2XEG A;  3FEC A;  4C84 A;  2C6G A;  2XEF A;  2EK8 A;  4JYW A;  4C9E A;  4OC4 A;  4C8T A;  4C8A A;  4NGR A;  4LQG A;  4C9R A;  4NGN A;  3SJE A;  1XF1 A;  3KAS A;  2EK9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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