3ICUA

Protease-associated domain of the e3 ligase grail
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
171
structure length
171
Chain Sequence
GAMDGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title PA Domain of the E3 Ligase Grail
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase RNF128
total genus 42
structure length 171
sequence length 171
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02225 PA PA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 3icuA01
4C8CA 2PVWA 2C6PA 1DE4C 5IB9A 4JZ0A 4OC2A 2EK8A 3IIBA 4C8UA 4C9RA 4CDJA 1Y9ZA 3S9MA 4C8TA 4KNGE 4C9EA 2XEJA 3D7HA 4MCSA 4NGTA 4OC0A 3I6SA 4C9VA 4JYWA 5D29A 4OMEA 3IWWA 4C8FA 4TJXA 4P4EA 2EK9A 4P4JA 4C84A 4TJVA 1WVMA 2JBKA 4P44A 4NGNA 3FECA 3S9NA 3ICUA 4NGRA 2XEFA 4C8AA 4OC1A 4OC5A 3FF3A 4TWEA 4NGPA 2OR4A 3SJEA 4NGQA 2XEGA 3VTAA 3D7FA 4C9AA 3BI0A 3KASA 2C6GA 3SJXA 5ELYA 4MCPA 3D7GA 4W9YA 3FEEA 1V6CA 4C9UA 4C99A 3BXMA 3BI1A 4OC4A 3D7DA 3S9LA 3I74A 1CX8A 1Z8LA 4C86A 2C6CA 2PVVA 4P4DA 4P45A 4OC3A 4P4BA 4LQGA 1XF1A 4C8PA 4NGMA 2OOTA 4X3RA 4YN3A 3EIFA 3SJFA 3SJGA 4MCRA 3FEDA 3RBUA 4P4IA 2XEIA 4C85A 5F09A 2CIJA 4CDKA 4NGSA 2JBJA 4P4FA 4MCQA 3BHXA
chains in the Genus database with same CATH superfamily
1C3OB 3TLCA 1CS0B 4C8CA 5F5XA 2B0AA 1C30B 3EZBA 2PVWA 2C6PA 1DE4C 4E5SA 4E94A 5IR2A 5IB9A 1NBWA 4INJA 4JZ0A 4OC2A 1ZRSA 2YJVA 2EK8A 3EZAA 3IIBA 3TLYA 4C8UA 5FD8A 4C9RA 4CDJA 1JDBC 1Y9ZA 3S9MA 4C8TA 4KNGE 3K4IA 4C9EA 2XEJA 3NOJA 3EZEA 3GJZA 3D7HA 2OLSA 2DIKA 4MCSA 4NGTA 4OC0A 1J3LA 1BXRB 3I6SA 5F9MA 2YJTA 4JYWA 4MJXA 3TLGB 4C9VA 5D29A 4OMEA 3IWWA 4C8FA 4TJXA 4P4EA 1KBLA 2EK9A 4P4JA 3TLBA 2AUNA 1A9XB 3G23A 4C84A 4TJVA 3TYXA 1WVMA 1VBGA 2JBKA 4P44A 4NGNA 3FECA 3S9NA 3ICUA 3TLAA 4NGRA 3TLGA 3TLZA 2AUMA 2XEFA 4C8AA 1CE8B 4EYSA 4OC1A 4J0NA 2EZBA 4OC5A 2MP0A 3FF3A 1T36B 1ZL0A 2EZCA 2FM4A 2E28A 4NGPA 4TWEA 1Q5XA 2OR4A 3SJEA 4NGQA 1R61A 4M8DA 2HWGA 2D0PA 2EZAA 2XEGA 3VTAA 2GP4A 3D7FA 4C9AA 3T05A 2D0OA 3BI0A 3KASA 2C6GA 3SJXA 5ELYA 4H1HA 4MCPA 3T5MA 4COBA 3D7GA 1M6VB 4W9YA 3FEEA 3T07A 2C5QA 1V6CA 2R82A 5K99A 1EZAA 4CZ1A 4C9UA 4C99A 3BXMA 2X0SA 1VBHA 3BI1A 3D7DA 4OC4A 3S9LA 3I74A 1CX8A 1Z8LA 4C86A 2C6CA 2PVVA 4P4DA 4P45A 4IIXA 1ZYMA 3KRVA 4OC3A 4P4BA 2HI6A 3SR3A 4LQGA 3K9TA 1XF1A 3T0TA 3U1BA 4C8PA 4NGMA 2OOTA 4JVOA 4X3RA 4YN3A 3EIFA 5JVLA 1EZBA 1NXJA 5F1YA 3SJFA 3SJGA 4MCRA 3FEDA 4IIYA 2PCNA 1DIKA 3RBUA 4P4IA 3TLEA 2XEIA 4C85A 4CO9A 5F09A 2CIJA 4CDKA 4NGSA 3C8OA 5JYBA 2JBJA 2HROA 1GGOA 4COGA 1VI4A 4P4FA 1JDEA 4MCQA 1KEEB 1KC7A 4MI1A 3BHXA
chains in the Genus database with same CATH topology
4C8CA 2PVWA 2C6PA 1DE4C 5IR2A 5IB9A 4JZ0A 4OC2A 2EK8A 3IIBA 4C8UA 4C9RA 4CDJA 1Y9ZA 3S9MA 4C8TA 4KNGE 4C9EA 2XEJA 3D7HA 4MCSA 4NGTA 4OC0A 3I6SA 4C9VA 4JYWA 5D29A 4OMEA 3IWWA 4C8FA 4TJXA 4P4EA 2EK9A 4P4JA 4C84A 4TJVA 1WVMA 2JBKA 4P44A 4NGNA 3FECA 3S9NA 3ICUA 4NGRA 2XEFA 4C8AA 4OC1A 4OC5A 3FF3A 4TWEA 4NGPA 2OR4A 3SJEA 4NGQA 2XEGA 3VTAA 2GP4A 3D7FA 4C9AA 3BI0A 3KASA 2C6GA 3SJXA 5ELYA 4MCPA 3D7GA 4W9YA 3FEEA 2C5QA 1V6CA 4C9UA 4C99A 3BXMA 3BI1A 4OC4A 3D7DA 3S9LA 3I74A 1CX8A 1Z8LA 4C86A 2C6CA 2PVVA 4P4DA 4P45A 4OC3A 4P4BA 4LQGA 3K9TA 1XF1A 4C8PA 4NGMA 2OOTA 4X3RA 4YN3A 3EIFA 3SJFA 3SJGA 4MCRA 3FEDA 3RBUA 4P4IA 2XEIA 4C85A 5F09A 2CIJA 4CDKA 4NGSA 2JBJA 4P4FA 4MCQA 3BHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C8C A;  2PVW A;  2C6P A;  1DE4 C;  5IB9 A;  4JZ0 A;  4OC2 A;  2EK8 A;  3IIB A;  4C8U A;  4C9R A;  4CDJ A;  1Y9Z A;  3S9M A;  4C8T A;  4KNG E;  4C9E A;  2XEJ A;  3D7H A;  4MCS A;  4NGT A;  4OC0 A;  3I6S A;  4C9V A;  4JYW A;  5D29 A;  4OME A;  3IWW A;  4C8F A;  4TJX A;  4P4E A;  2EK9 A;  4P4J A;  4C84 A;  4TJV A;  1WVM A;  2JBK A;  4P44 A;  4NGN A;  3FEC A;  3S9N A;  3ICU A;  4NGR A;  2XEF A;  4C8A A;  4OC1 A;  4OC5 A;  3FF3 A;  4TWE A;  4NGP A;  2OR4 A;  3SJE A;  4NGQ A;  2XEG A;  3VTA A;  3D7F A;  4C9A A;  3BI0 A;  3KAS A;  2C6G A;  3SJX A;  5ELY A;  4MCP A;  3D7G A;  4W9Y A;  3FEE A;  1V6C A;  4C9U A;  4C99 A;  3BXM A;  3BI1 A;  4OC4 A;  3D7D A;  3S9L A;  3I74 A;  1CX8 A;  1Z8L A;  4C86 A;  2C6C A;  2PVV A;  4P4D A;  4P45 A;  4OC3 A;  4P4B A;  4LQG A;  1XF1 A;  4C8P A;  4NGM A;  2OOT A;  4X3R A;  4YN3 A;  3EIF A;  3SJF A;  3SJG A;  4MCR A;  3FED A;  3RBU A;  4P4I A;  2XEI A;  4C85 A;  5F09 A;  2CIJ A;  4CDK A;  4NGS A;  2JBJ A;  4P4F A;  4MCQ A;  3BHX A; 
#chains in the Genus database with same CATH topology
 1C3O B;  3TLC A;  1CS0 B;  4C8C A;  5F5X A;  2B0A A;  1C30 B;  3EZB A;  2PVW A;  2C6P A;  1DE4 C;  4E5S A;  4E94 A;  5IR2 A;  5IB9 A;  1NBW A;  4INJ A;  4JZ0 A;  4OC2 A;  1ZRS A;  2YJV A;  2EK8 A;  3EZA A;  3IIB A;  3TLY A;  4C8U A;  5FD8 A;  4C9R A;  4CDJ A;  1JDB C;  1Y9Z A;  3S9M A;  4C8T A;  4KNG E;  3K4I A;  4C9E A;  2XEJ A;  3NOJ A;  3EZE A;  3GJZ A;  3D7H A;  2OLS A;  2DIK A;  4MCS A;  4NGT A;  4OC0 A;  1J3L A;  1BXR B;  3I6S A;  5F9M A;  2YJT A;  4JYW A;  4MJX A;  3TLG B;  4C9V A;  5D29 A;  4OME A;  3IWW A;  4C8F A;  4TJX A;  4P4E A;  1KBL A;  2EK9 A;  4P4J A;  3TLB A;  2AUN A;  1A9X B;  3G23 A;  4C84 A;  4TJV A;  3TYX A;  1WVM A;  1VBG A;  2JBK A;  4P44 A;  4NGN A;  3FEC A;  3S9N A;  3ICU A;  3TLA A;  4NGR A;  3TLG A;  3TLZ A;  2AUM A;  2XEF A;  4C8A A;  1CE8 B;  4EYS A;  4OC1 A;  4J0N A;  2EZB A;  4OC5 A;  2MP0 A;  3FF3 A;  1T36 B;  1ZL0 A;  2EZC A;  2FM4 A;  2E28 A;  4NGP A;  4TWE A;  1Q5X A;  2OR4 A;  3SJE A;  4NGQ A;  1R61 A;  4M8D A;  2HWG A;  2D0P A;  2EZA A;  2XEG A;  3VTA A;  2GP4 A;  3D7F A;  4C9A A;  3T05 A;  2D0O A;  3BI0 A;  3KAS A;  2C6G A;  3SJX A;  5ELY A;  4H1H A;  4MCP A;  3T5M A;  4COB A;  3D7G A;  1M6V B;  4W9Y A;  3FEE A;  3T07 A;  2C5Q A;  1V6C A;  2R82 A;  5K99 A;  1EZA A;  4CZ1 A;  4C9U A;  4C99 A;  3BXM A;  2X0S A;  1VBH A;  3BI1 A;  3D7D A;  4OC4 A;  3S9L A;  3I74 A;  1CX8 A;  1Z8L A;  4C86 A;  2C6C A;  2PVV A;  4P4D A;  4P45 A;  4IIX A;  1ZYM A;  3KRV A;  4OC3 A;  4P4B A;  2HI6 A;  3SR3 A;  4LQG A;  3K9T A;  1XF1 A;  3T0T A;  3U1B A;  4C8P A;  4NGM A;  2OOT A;  4JVO A;  4X3R A;  4YN3 A;  3EIF A;  5JVL A;  1EZB A;  1NXJ A;  5F1Y A;  3SJF A;  3SJG A;  4MCR A;  3FED A;  4IIY A;  2PCN A;  1DIK A;  3RBU A;  4P4I A;  3TLE A;  2XEI A;  4C85 A;  4CO9 A;  5F09 A;  2CIJ A;  4CDK A;  4NGS A;  3C8O A;  5JYB A;  2JBJ A;  2HRO A;  1GGO A;  4COG A;  1VI4 A;  4P4F A;  1JDE A;  4MCQ A;  1KEE B;  1KC7 A;  4MI1 A;  3BHX A; 
#chains in the Genus database with same CATH homology
 4C8C A;  2PVW A;  2C6P A;  1DE4 C;  5IR2 A;  5IB9 A;  4JZ0 A;  4OC2 A;  2EK8 A;  3IIB A;  4C8U A;  4C9R A;  4CDJ A;  1Y9Z A;  3S9M A;  4C8T A;  4KNG E;  4C9E A;  2XEJ A;  3D7H A;  4MCS A;  4NGT A;  4OC0 A;  3I6S A;  4C9V A;  4JYW A;  5D29 A;  4OME A;  3IWW A;  4C8F A;  4TJX A;  4P4E A;  2EK9 A;  4P4J A;  4C84 A;  4TJV A;  1WVM A;  2JBK A;  4P44 A;  4NGN A;  3FEC A;  3S9N A;  3ICU A;  4NGR A;  2XEF A;  4C8A A;  4OC1 A;  4OC5 A;  3FF3 A;  4TWE A;  4NGP A;  2OR4 A;  3SJE A;  4NGQ A;  2XEG A;  3VTA A;  2GP4 A;  3D7F A;  4C9A A;  3BI0 A;  3KAS A;  2C6G A;  3SJX A;  5ELY A;  4MCP A;  3D7G A;  4W9Y A;  3FEE A;  2C5Q A;  1V6C A;  4C9U A;  4C99 A;  3BXM A;  3BI1 A;  4OC4 A;  3D7D A;  3S9L A;  3I74 A;  1CX8 A;  1Z8L A;  4C86 A;  2C6C A;  2PVV A;  4P4D A;  4P45 A;  4OC3 A;  4P4B A;  4LQG A;  3K9T A;  1XF1 A;  4C8P A;  4NGM A;  2OOT A;  4X3R A;  4YN3 A;  3EIF A;  3SJF A;  3SJG A;  4MCR A;  3FED A;  3RBU A;  4P4I A;  2XEI A;  4C85 A;  5F09 A;  2CIJ A;  4CDK A;  4NGS A;  2JBJ A;  4P4F A;  4MCQ A;  3BHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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