4C8CA

Mouse znrf3 ectodomain crystal form iii
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
151
structure length
146
Chain Sequence
ETAFVEVVLFESSPSGDYTTHTTGLTGRFSRAGAMLSAEGEIVQMHPLGLCEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPVVYVKGADAIKLMNIVNKQKVARARIQH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
source organism Mus musculus
publication title Structural and Molecular Basis of Znrf3/Rnf43 Transmembrane Ubiquitin Ligase Inhibition by the Wnt Agonist R-Spondin.
pubmed doi rcsb
molecule keywords E3 UBIQUITIN-PROTEIN LIGASE ZNRF3
total genus 37
structure length 146
sequence length 151
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18212 ZNRF_3_ecto ZNRF-3 Ectodomain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.30.30 Alpha Beta 3-Layer(bba) Sandwich Glucose Oxidase; domain 1 Glucose Oxidase; domain 1 4c8cA00
3BI1A 4JZ0A 3FECA 2OOTA 3D7DA 2EK8A 2XEIA 3IWWA 4JYWA 4NGTA 4CDJA 4NGSA 3RBUA 3D7GA 4C9RA 1V6CA 4C8PA 3EIFA 3ICUA 3IIBA 2OR4A 2XEJA 5D29A 4NGPA 3D7HA 4OC0A 3FEDA 3SJXA 3S9MA 4TJXA 4CDKA 4OC3A 2EK9A 3SJFA 4C8AA 4C8FA 4C8UA 4X3RA 2C6PA 1CX8A 3BXMA 4TWEA 4P4DA 1Z8LA 4OC4A 4NGMA 2CIJA 4MCPA 4P4IA 4C85A 3VTAA 5F09A 4C99A 4C8TA 5IB9A 4C9VA 5ELYA 4NGQA 2JBKA 4P4JA 4MCRA 4P4EA 4C9AA 3BHXA 4OMEA 4C9EA 2C6CA 4P4FA 2XEFA 4NGNA 4OC5A 1WVMA 4C8CA 4C84A 3D7FA 4P4BA 3SJEA 4P45A 2JBJA 2PVVA 4C86A 4NGRA 4C9UA 2XEGA 3BI0A 3FEEA 4OC2A 2PVWA 4YN3A 4P44A 3I74A 1Y9ZA 1XF1A 4KNGE 2C6GA 3SJGA 4OC1A 3FF3A 3S9LA 1DE4C 4MCSA 4LQGA 4TJVA 3KASA 4MCQA 3I6SA 4W9YA 3S9NA
chains in the Genus database with same CATH superfamily
2OLSA 3BI1A 1T36B 2DIKA 2YJTA 4JZ0A 1KC7A 2EZAA 3T05A 3FECA 2OOTA 3SR3A 3D7DA 5K99A 2EK8A 2HWGA 4H1HA 3TLZA 2XEIA 1EZAA 3IWWA 4JYWA 4NGTA 4CDJA 4NGSA 1DIKA 2E28A 3RBUA 3D7GA 4C9RA 1NXJA 1V6CA 5F1YA 4C8PA 3EIFA 3ICUA 1ZRSA 2GP4A 4MJXA 1VBHA 3IIBA 1VBGA 2X0SA 4COBA 1Q5XA 2OR4A 4IIXA 2XEJA 5D29A 3TLAA 4NGPA 3D7HA 4OC0A 3FEDA 5IR2A 3S9MA 4TJXA 3SJXA 4CDKA 3G23A 4OC3A 3EZBA 3TLCA 1M6VB 2EK9A 4CZ1A 3SJFA 4C8AA 4C8FA 4C8UA 4X3RA 3TLBA 2C6PA 1CX8A 3BXMA 4P4DA 4TWEA 1ZL0A 4J0NA 1Z8LA 4OC4A 4NGMA 2CIJA 4E94A 4MCPA 1J3LA 4P4IA 2HI6A 4C85A 2EZCA 3VTAA 3TLEA 5F09A 1C30B 1ZYMA 4C99A 4EYSA 4C8TA 5IB9A 4C9VA 5ELYA 4NGQA 5F9MA 4COGA 3NOJA 2JBKA 4P4JA 4MCRA 1NBWA 4P4EA 1KEEB 3BHXA 4C9AA 2D0OA 4JVOA 4OMEA 3T5MA 3TLGA 4C9EA 2C6CA 1JDBC 4P4FA 5JYBA 1VI4A 2XEFA 4NGNA 4IIYA 4OC5A 1WVMA 4C8CA 4C84A 3D7FA 4P4BA 1CE8B 2B0AA 5FD8A 3SJEA 1JDEA 1BXRB 2R82A 2HROA 1A9XB 4CO9A 4P45A 2JBJA 2PVVA 3T0TA 4C86A 4E5SA 4NGRA 3K4IA 2MP0A 3K9TA 2AUNA 4C9UA 2XEGA 5JVLA 4MI1A 3T07A 3U1BA 1C3OB 3BI0A 3GJZA 2D0PA 3FEEA 4OC2A 2PVWA 4YN3A 4P44A 3I74A 2PCNA 1Y9ZA 3TLGB 1XF1A 3EZAA 2C6GA 4KNGE 3TYXA 3SJGA 4OC1A 2FM4A 5F5XA 4INJA 3FF3A 2EZBA 3EZEA 1KBLA 1GGOA 3KRVA 1EZBA 3S9LA 1DE4C 1CS0B 2YJVA 3TLYA 4M8DA 4MCSA 4LQGA 4TJVA 3KASA 4MCQA 2AUMA 2C5QA 1R61A 3I6SA 4W9YA 3C8OA 3S9NA
chains in the Genus database with same CATH topology
3BI1A 4JZ0A 3FECA 2OOTA 3D7DA 2EK8A 2XEIA 3IWWA 4JYWA 4NGTA 4CDJA 4NGSA 3RBUA 3D7GA 4C9RA 1V6CA 4C8PA 3EIFA 3ICUA 2GP4A 3IIBA 2OR4A 2XEJA 5D29A 4NGPA 3D7HA 4OC0A 3FEDA 5IR2A 3S9MA 4TJXA 3SJXA 4CDKA 4OC3A 2EK9A 3SJFA 4C8AA 4C8FA 4C8UA 4X3RA 2C6PA 1CX8A 3BXMA 4TWEA 4P4DA 1Z8LA 4OC4A 4NGMA 2CIJA 4MCPA 4P4IA 4C85A 3VTAA 5F09A 4C99A 4C8TA 5IB9A 4C9VA 5ELYA 4NGQA 2JBKA 4P4JA 4MCRA 4P4EA 4C9AA 3BHXA 4OMEA 4C9EA 2C6CA 4P4FA 2XEFA 4NGNA 4OC5A 1WVMA 4C8CA 4C84A 3D7FA 4P4BA 3SJEA 4P45A 2JBJA 2PVVA 4C86A 4NGRA 3K9TA 4C9UA 2XEGA 3BI0A 3FEEA 4OC2A 2PVWA 4YN3A 4P44A 3I74A 1Y9ZA 1XF1A 4KNGE 2C6GA 3SJGA 4OC1A 3FF3A 3S9LA 1DE4C 4MCSA 4LQGA 4TJVA 3KASA 4MCQA 2C5QA 3I6SA 4W9YA 3S9NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BI1 A;  4JZ0 A;  3FEC A;  2OOT A;  3D7D A;  2EK8 A;  2XEI A;  3IWW A;  4JYW A;  4NGT A;  4CDJ A;  4NGS A;  3RBU A;  3D7G A;  4C9R A;  1V6C A;  4C8P A;  3EIF A;  3ICU A;  3IIB A;  2OR4 A;  2XEJ A;  5D29 A;  4NGP A;  3D7H A;  4OC0 A;  3FED A;  3SJX A;  3S9M A;  4TJX A;  4CDK A;  4OC3 A;  2EK9 A;  3SJF A;  4C8A A;  4C8F A;  4C8U A;  4X3R A;  2C6P A;  1CX8 A;  3BXM A;  4TWE A;  4P4D A;  1Z8L A;  4OC4 A;  4NGM A;  2CIJ A;  4MCP A;  4P4I A;  4C85 A;  3VTA A;  5F09 A;  4C99 A;  4C8T A;  5IB9 A;  4C9V A;  5ELY A;  4NGQ A;  2JBK A;  4P4J A;  4MCR A;  4P4E A;  4C9A A;  3BHX A;  4OME A;  4C9E A;  2C6C A;  4P4F A;  2XEF A;  4NGN A;  4OC5 A;  1WVM A;  4C8C A;  4C84 A;  3D7F A;  4P4B A;  3SJE A;  4P45 A;  2JBJ A;  2PVV A;  4C86 A;  4NGR A;  4C9U A;  2XEG A;  3BI0 A;  3FEE A;  4OC2 A;  2PVW A;  4YN3 A;  4P44 A;  3I74 A;  1Y9Z A;  1XF1 A;  4KNG E;  2C6G A;  3SJG A;  4OC1 A;  3FF3 A;  3S9L A;  1DE4 C;  4MCS A;  4LQG A;  4TJV A;  3KAS A;  4MCQ A;  3I6S A;  4W9Y A;  3S9N A; 
#chains in the Genus database with same CATH topology
 2OLS A;  3BI1 A;  1T36 B;  2DIK A;  2YJT A;  4JZ0 A;  1KC7 A;  2EZA A;  3T05 A;  3FEC A;  2OOT A;  3SR3 A;  3D7D A;  5K99 A;  2EK8 A;  2HWG A;  4H1H A;  3TLZ A;  2XEI A;  1EZA A;  3IWW A;  4JYW A;  4NGT A;  4CDJ A;  4NGS A;  1DIK A;  2E28 A;  3RBU A;  3D7G A;  4C9R A;  1NXJ A;  1V6C A;  5F1Y A;  4C8P A;  3EIF A;  3ICU A;  1ZRS A;  2GP4 A;  4MJX A;  1VBH A;  3IIB A;  1VBG A;  2X0S A;  4COB A;  1Q5X A;  2OR4 A;  4IIX A;  2XEJ A;  5D29 A;  3TLA A;  4NGP A;  3D7H A;  4OC0 A;  3FED A;  5IR2 A;  3S9M A;  4TJX A;  3SJX A;  4CDK A;  3G23 A;  4OC3 A;  3EZB A;  3TLC A;  1M6V B;  2EK9 A;  4CZ1 A;  3SJF A;  4C8A A;  4C8F A;  4C8U A;  4X3R A;  3TLB A;  2C6P A;  1CX8 A;  3BXM A;  4P4D A;  4TWE A;  1ZL0 A;  4J0N A;  1Z8L A;  4OC4 A;  4NGM A;  2CIJ A;  4E94 A;  4MCP A;  1J3L A;  4P4I A;  2HI6 A;  4C85 A;  2EZC A;  3VTA A;  3TLE A;  5F09 A;  1C30 B;  1ZYM A;  4C99 A;  4EYS A;  4C8T A;  5IB9 A;  4C9V A;  5ELY A;  4NGQ A;  5F9M A;  4COG A;  3NOJ A;  2JBK A;  4P4J A;  4MCR A;  1NBW A;  4P4E A;  1KEE B;  3BHX A;  4C9A A;  2D0O A;  4JVO A;  4OME A;  3T5M A;  3TLG A;  4C9E A;  2C6C A;  1JDB C;  4P4F A;  5JYB A;  1VI4 A;  2XEF A;  4NGN A;  4IIY A;  4OC5 A;  1WVM A;  4C8C A;  4C84 A;  3D7F A;  4P4B A;  1CE8 B;  2B0A A;  5FD8 A;  3SJE A;  1JDE A;  1BXR B;  2R82 A;  2HRO A;  1A9X B;  4CO9 A;  4P45 A;  2JBJ A;  2PVV A;  3T0T A;  4C86 A;  4E5S A;  4NGR A;  3K4I A;  2MP0 A;  3K9T A;  2AUN A;  4C9U A;  2XEG A;  5JVL A;  4MI1 A;  3T07 A;  3U1B A;  1C3O B;  3BI0 A;  3GJZ A;  2D0P A;  3FEE A;  4OC2 A;  2PVW A;  4YN3 A;  4P44 A;  3I74 A;  2PCN A;  1Y9Z A;  3TLG B;  1XF1 A;  3EZA A;  2C6G A;  4KNG E;  3TYX A;  3SJG A;  4OC1 A;  2FM4 A;  5F5X A;  4INJ A;  3FF3 A;  2EZB A;  3EZE A;  1KBL A;  1GGO A;  3KRV A;  1EZB A;  3S9L A;  1DE4 C;  1CS0 B;  2YJV A;  3TLY A;  4M8D A;  4MCS A;  4LQG A;  4TJV A;  3KAS A;  4MCQ A;  2AUM A;  2C5Q A;  1R61 A;  3I6S A;  4W9Y A;  3C8O A;  3S9N A; 
#chains in the Genus database with same CATH homology
 3BI1 A;  4JZ0 A;  3FEC A;  2OOT A;  3D7D A;  2EK8 A;  2XEI A;  3IWW A;  4JYW A;  4NGT A;  4CDJ A;  4NGS A;  3RBU A;  3D7G A;  4C9R A;  1V6C A;  4C8P A;  3EIF A;  3ICU A;  2GP4 A;  3IIB A;  2OR4 A;  2XEJ A;  5D29 A;  4NGP A;  3D7H A;  4OC0 A;  3FED A;  5IR2 A;  3S9M A;  4TJX A;  3SJX A;  4CDK A;  4OC3 A;  2EK9 A;  3SJF A;  4C8A A;  4C8F A;  4C8U A;  4X3R A;  2C6P A;  1CX8 A;  3BXM A;  4TWE A;  4P4D A;  1Z8L A;  4OC4 A;  4NGM A;  2CIJ A;  4MCP A;  4P4I A;  4C85 A;  3VTA A;  5F09 A;  4C99 A;  4C8T A;  5IB9 A;  4C9V A;  5ELY A;  4NGQ A;  2JBK A;  4P4J A;  4MCR A;  4P4E A;  4C9A A;  3BHX A;  4OME A;  4C9E A;  2C6C A;  4P4F A;  2XEF A;  4NGN A;  4OC5 A;  1WVM A;  4C8C A;  4C84 A;  3D7F A;  4P4B A;  3SJE A;  4P45 A;  2JBJ A;  2PVV A;  4C86 A;  4NGR A;  3K9T A;  4C9U A;  2XEG A;  3BI0 A;  3FEE A;  4OC2 A;  2PVW A;  4YN3 A;  4P44 A;  3I74 A;  1Y9Z A;  1XF1 A;  4KNG E;  2C6G A;  3SJG A;  4OC1 A;  3FF3 A;  3S9L A;  1DE4 C;  4MCS A;  4LQG A;  4TJV A;  3KAS A;  4MCQ A;  2C5Q A;  3I6S A;  4W9Y A;  3S9N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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